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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene Breakpoints

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness

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Fusion Genomic Features

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Fusion Gene ORF Annotations

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Fusion Protein Retained/Non-Retained Functional Features

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Fusion Transcript Sequences

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Fusion Protein Sequences

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Personalized Fusion Protein Sequences

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Fusion Gene Expressed Samples

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Related Drugs

Fusion gene:ABI2_PPP1R1C (FusionGDB2 ID:HG10152TG151242)

Fusion Gene Summary for ABI2_PPP1R1C

check button Fusion gene summary
Fusion gene informationFusion gene name: ABI2_PPP1R1C
Fusion gene ID: hg10152tg151242
HgeneTgene
Gene symbol

ABI2

PPP1R1C

Gene ID

10152

151242

Gene nameabl interactor 2protein phosphatase 1 regulatory inhibitor subunit 1C
SynonymsABI-2|ABI2B|AIP-1|AIP1|AblBP3|SSH3BP2|argBP1|argBPIA|argBPIBIPP5
Cytomap

2q33.2

2q31.3-q32.1

Type of geneprotein-codingprotein-coding
Descriptionabl interactor 2abelson interactor 2abl binding protein 3abl-interacting protein 1 (SH3-containing protein)abl-interactor protein 2barg protein tyrosine kinase-binding proteinarg-binding protein 1protein phosphatase 1 regulatory subunit 1CPP1 inhibitor protein 5inhibitor-5 of protein phosphatase 1protein phosphatase 1 regulatory subunit 1A
Modification date2024041120240305
UniProtAcc

Q9NYB9

.
Ensembl transtripts involved in fusion geneENST00000261017, ENST00000295851, 
ENST00000422511, ENST00000424558, 
ENST00000430418, ENST00000261016, 
ENST00000261018, ENST00000430574, 
Fusion gene scores* DoF score* DoF score (Degree of Frequency) = # partners X # break points X # disease types
18 X 12 X 11=2376		* DoF score (Degree of Frequency) = # partners X # break points X # disease types
2 X 6 X 5=60
# samples 3011
** MAII score** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(30/2376*10)=-2.98550043030489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(11/60*10)=0.874469117916141
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ABI2 [Title/Abstract] AND PPP1R1C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABI2(204193354)-PPP1R1C(182926168), # samples:1


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Fusion Gene Breakpoints for ABI2_PPP1R1C


check button RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbp
ABI2chr2204193354PPP1R1Cchr2204193354
ABI2chr2204193354PPP1R1Cchr2182926169


check button DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbpSV type


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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for ABI2_PPP1R1C


check button To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.
* We have 10 tumorigenic mechanism categories of fusion genes as shown below.
Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand FusionsAberrant Chimeric Transcription Factor / Fusion Transcription Factor ActivityEpigenetic Reprogramming / Histone Modifier DysregulationChromatin Remodeling DysregulationCondensate-Driven Transcriptional Rewiring / LLPPromoter / Enhancer HijackingDominant-Negative AntagonismCell Cycle / Checkpoint Bypass / RNA Processing DysregulationSubcellular Mislocalization / Spatial DysregulationNuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABI2

Q9NYB9

.

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABI2

GO:0010592

positive regulation of lamellipodium assembly

21107423

HgeneABI2

GO:0016601

Rac protein signal transduction

21107423

HgeneABI2

GO:0018108

peptidyl-tyrosine phosphorylation

17101133

HgeneABI2

GO:2000601

positive regulation of Arp2/3 complex-mediated actin nucleation

21107423


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Fusion Genomic Features for ABI2_PPP1R1C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABI2chr2204193354+PPP1R1Cchr2182926168+3.70e-081.00e+00


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).
genomic feature

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Fusion Gene ORF Annotations for ABI2_PPP1R1C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000261017ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000261017ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000261017ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000261017ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000261017ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000295851ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000295851ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000295851ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000295851ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000295851ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000422511ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000422511ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000422511ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000422511ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000422511ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000424558ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000424558ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000424558ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000424558ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000424558ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000430418ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000430418ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000430418ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000430418ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5CDS-3UTRENST00000430418ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5UTR-3UTRENST00000261016ENST00000280295ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5UTR-3UTRENST00000261016ENST00000409137ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5UTR-3UTRENST00000261016ENST00000409702ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5UTR-3UTRENST00000261016ENST00000452904ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+
5UTR-3UTRENST00000261016ENST00000475249ABI2chr2

204193354

+PPP1R1Cchr2

182926168

+

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score
ENST00000422511ENST00000409702ABI2chr2204193354PPP1R1Cchr21829261680.00e+007.48e-01
ENST00000430418ENST00000475249ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.68e-03
ENST00000430418ENST00000452904ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.68e-01
ENST00000430418ENST00000409702ABI2chr2204193354PPP1R1Cchr21829261680.00e+006.84e-01
ENST00000430418ENST00000409137ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.60e-01
ENST00000430418ENST00000280295ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.31e-01
ENST00000424558ENST00000475249ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.03e-03
ENST00000424558ENST00000452904ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.64e-01
ENST00000424558ENST00000409702ABI2chr2204193354PPP1R1Cchr21829261680.00e+006.59e-01
ENST00000424558ENST00000409137ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.63e-01
ENST00000424558ENST00000280295ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.19e-01
ENST00000422511ENST00000475249ABI2chr2204193354PPP1R1Cchr21829261680.00e+004.78e-03
ENST00000422511ENST00000452904ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.50e-01
ENST00000261017ENST00000280295ABI2chr2204193354PPP1R1Cchr21829261680.00e+005.96e-01
ENST00000422511ENST00000409137ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.82e-01
ENST00000422511ENST00000280295ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.83e-01
ENST00000295851ENST00000475249ABI2chr2204193354PPP1R1Cchr21829261680.00e+002.78e-02
ENST00000295851ENST00000452904ABI2chr2204193354PPP1R1Cchr21829261680.00e+006.70e-01
ENST00000295851ENST00000409702ABI2chr2204193354PPP1R1Cchr21829261680.00e+005.63e-01
ENST00000295851ENST00000409137ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.40e-01
ENST00000295851ENST00000280295ABI2chr2204193354PPP1R1Cchr21829261680.00e+008.20e-01
ENST00000261017ENST00000475249ABI2chr2204193354PPP1R1Cchr21829261680.00e+002.63e-02
ENST00000261017ENST00000452904ABI2chr2204193354PPP1R1Cchr21829261680.00e+006.36e-01
ENST00000261017ENST00000409702ABI2chr2204193354PPP1R1Cchr21829261680.00e+005.74e-01
ENST00000261017ENST00000409137ABI2chr2204193354PPP1R1Cchr21829261680.00e+009.29e-01

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Fusion Protein Retained/Non-Retained Functional Features for ABI2_PPP1R1C

check buttonProtein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.
fgviewer annotation
- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).
No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


check button - Retained PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Fusion Transcript Sequence for ABI2_PPP1R1C

check button In-frame Fusion Transcript Sequences.

check button N-Truncated Transcript (5UTR-3CDS) Sequences

check button C-Truncated Transcript (5CDS-3UTR) Sequences
>ABI2_PPP1R1C_ENST00000261017_ENST00000280295_204193354_182926168 length=1591nt
Breakpoint=352nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTC
CTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAG
CTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAA
GGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTA
CTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTT
ATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAG
CCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTG
CCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATG
ACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTC
CTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCT
TGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAA

>ABI2_PPP1R1C_ENST00000261017_ENST00000409137_204193354_182926168 length=2971nt
Breakpoint=352nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTC
CTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAG
CTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAA
GGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTA
CTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTT
ATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAG
CCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTG
CCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATG
ACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTC
CTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCT
TGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAATGTTTCCTATGTCTAAATCTATATTTTAAAAATAACCTTTATCATGTAAAATGAGAGAA
TTGCTGAGTTTATGACAATCTTAGGTATAACCTTTTCTTAAAGAACAAGGCATCAATCTTTAATTTGTTTCCCTTTCTTGATTTCTCATAAGTTGCAAAATAAAAATAAAAATAATTTCACAAATTGTTCATTATTATTATCCTCCCTAC
TTGCCCCAGGATTTAAGTACTAACTTTTACTTCCTACTCTTAGACTTTGTATTGCCAAAGAAATAAAATATGAAAAAGCATAATCACCCAGACCTACCTGCGGAATTGTGGATTATGCTGTAGATATTAGATCATTGAAAGGAACAATAT
ACTACTTAATGAGGAGCCAAAGACAACATTCTACCTGCTGCTCCCTTCAAGCTGAGGAATGAGTTTAATTGACTTCAAAGTCCCATTATTCTCAAAAGTAGCAAAGGTACAACATGGCTTTGCATGAATCAAAGGAAGGGAACAACAAGA
ACTTAAAAAAATAGTTTGCAGATGGTTGAACATCTCTTTAATAATTAGAGAAGAATATCTTTTCTTTCTTTATTGTTTACAGATACCAACATTTTTCAAAGCCTTGCAGTAGATGAGTGAGTCTCCTGTTACATTTCTCCTGCAGCATAT
ATTCTGTGGATGTGTTTTCCTAAGCAGACTAATTATATGTTGCTCTCTTCTTTTACCCTAATGAAACATAGATTTTTCTGTTTTGAATTTGTCACTTGTTTGTTACATTTGTCAAGTGTTTTAAATATTACATTGGTCCTTTATTTGCTT
TTGAGAACACCCAATAGTTTAAAAATTAAAATGACATGAAGGTCAATTCTAAGACAGGAATGATACTACTAAATCCTGGACTTGCCTATGATAACAAGCTCGAGCTACACACTTTTATTGTCAGAATAAATGGAATATATAGGAAGGAGT
TAATTGGAACTGGTTAGTACCTAAATAAGATTTTTCAAAGTAAGTTTTTTGTCGTATTGGCAGAACAGTGTTAAAAAATAGACATTGTCATCATAAACACCCACAACTATATCTGTAGAAGATAATTTAATGCAATATTCTGGGGAAAAT
ACAGTTGCCAAAATTAATCTCCTTGTTTTCTTTCATTGTGCAATGTGGAGTTAAATTTTTTTTCTATTGAGCAGTGTGTGTGTGTGTTTGTGTCTATAATTTATATATGTGCTTGTATACATTTCTATATACACATGTATGTGTATGCAA
AATATGTATATATACACATATATATAAAATGTACACTAAATATGTATATATGTATATTCATAAAATGTTTTGCTGTATGGAAATAAAAAAGAAGGTTTCTAAAGGAAAGATAGAGAAGAAA

>ABI2_PPP1R1C_ENST00000261017_ENST00000409702_204193354_182926168 length=1278nt
Breakpoint=352nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTC
CTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAG
CTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAA
GGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTA
TACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTG
TTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAG
AAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTC
TAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTAC
TGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCC

>ABI2_PPP1R1C_ENST00000261017_ENST00000452904_204193354_182926168 length=937nt
Breakpoint=352nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTC
CTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAG
CTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAA
GGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTA
TACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGTACACATTGTTCCACATCACTTATAATTAAAGAATA
AGCATTTATTTTACAGTGATTCTTCTTTTTAACTATGTAAAAATTTGCATACATGTGACTGTTCTAACTTTAATACTGCCAGAGCTTAATCCTTGATGTCCTACTGATAAGGTTTGCATTCTAACAACACATGTAAATAACATCACTTTA
AGAGTAAAAAATAAATAGTAAACACATTTAGACATGA

>ABI2_PPP1R1C_ENST00000261017_ENST00000475249_204193354_182926168 length=352nt
Breakpoint=352nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTC
CTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAG
CTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAG

>ABI2_PPP1R1C_ENST00000295851_ENST00000280295_204193354_182926168 length=1652nt
Breakpoint=413nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTG
TCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGG
CGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGA
ATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTA
ATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGA
AGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGA
TCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTT
CAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTA
TTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCC
ACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAG
GCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAA
AA

>ABI2_PPP1R1C_ENST00000295851_ENST00000409137_204193354_182926168 length=3032nt
Breakpoint=413nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTG
TCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGG
CGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGA
ATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTA
ATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGA
AGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGA
TCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTT
CAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTA
TTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCC
ACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAG
GCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAA
AATGTTTCCTATGTCTAAATCTATATTTTAAAAATAACCTTTATCATGTAAAATGAGAGAATTGCTGAGTTTATGACAATCTTAGGTATAACCTTTTCTTAAAGAACAAGGCATCAATCTTTAATTTGTTTCCCTTTCTTGATTTCTCAT
AAGTTGCAAAATAAAAATAAAAATAATTTCACAAATTGTTCATTATTATTATCCTCCCTACTTGCCCCAGGATTTAAGTACTAACTTTTACTTCCTACTCTTAGACTTTGTATTGCCAAAGAAATAAAATATGAAAAAGCATAATCACCC
AGACCTACCTGCGGAATTGTGGATTATGCTGTAGATATTAGATCATTGAAAGGAACAATATACTACTTAATGAGGAGCCAAAGACAACATTCTACCTGCTGCTCCCTTCAAGCTGAGGAATGAGTTTAATTGACTTCAAAGTCCCATTAT
TCTCAAAAGTAGCAAAGGTACAACATGGCTTTGCATGAATCAAAGGAAGGGAACAACAAGAACTTAAAAAAATAGTTTGCAGATGGTTGAACATCTCTTTAATAATTAGAGAAGAATATCTTTTCTTTCTTTATTGTTTACAGATACCAA
CATTTTTCAAAGCCTTGCAGTAGATGAGTGAGTCTCCTGTTACATTTCTCCTGCAGCATATATTCTGTGGATGTGTTTTCCTAAGCAGACTAATTATATGTTGCTCTCTTCTTTTACCCTAATGAAACATAGATTTTTCTGTTTTGAATT
TGTCACTTGTTTGTTACATTTGTCAAGTGTTTTAAATATTACATTGGTCCTTTATTTGCTTTTGAGAACACCCAATAGTTTAAAAATTAAAATGACATGAAGGTCAATTCTAAGACAGGAATGATACTACTAAATCCTGGACTTGCCTAT
GATAACAAGCTCGAGCTACACACTTTTATTGTCAGAATAAATGGAATATATAGGAAGGAGTTAATTGGAACTGGTTAGTACCTAAATAAGATTTTTCAAAGTAAGTTTTTTGTCGTATTGGCAGAACAGTGTTAAAAAATAGACATTGTC
ATCATAAACACCCACAACTATATCTGTAGAAGATAATTTAATGCAATATTCTGGGGAAAATACAGTTGCCAAAATTAATCTCCTTGTTTTCTTTCATTGTGCAATGTGGAGTTAAATTTTTTTTCTATTGAGCAGTGTGTGTGTGTGTTT
GTGTCTATAATTTATATATGTGCTTGTATACATTTCTATATACACATGTATGTGTATGCAAAATATGTATATATACACATATATATAAAATGTACACTAAATATGTATATATGTATATTCATAAAATGTTTTGCTGTATGGAAATAAAAA
AGAAGGTTTCTAAAGGAAAGATAGAGAAGAAA

>ABI2_PPP1R1C_ENST00000295851_ENST00000409702_204193354_182926168 length=1339nt
Breakpoint=413nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTG
TCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGG
CGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGA
ATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTA
ATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTC
TCCTTGACTGAACTTTAGAACTAAGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCT
ACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTC
TACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTA
TTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCC

>ABI2_PPP1R1C_ENST00000295851_ENST00000452904_204193354_182926168 length=998nt
Breakpoint=413nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTG
TCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGG
CGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGA
ATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTA
ATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTC
TCCTTGACTGAACTTTAGAACTAAGTACACATTGTTCCACATCACTTATAATTAAAGAATAAGCATTTATTTTACAGTGATTCTTCTTTTTAACTATGTAAAAATTTGCATACATGTGACTGTTCTAACTTTAATACTGCCAGAGCTTAA
TCCTTGATGTCCTACTGATAAGGTTTGCATTCTAACAACACATGTAAATAACATCACTTTAAGAGTAAAAAATAAATAGTAAACACATTTAGACATGA

>ABI2_PPP1R1C_ENST00000295851_ENST00000475249_204193354_182926168 length=413nt
Breakpoint=413nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTG
TCGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGG
CGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAG

>ABI2_PPP1R1C_ENST00000422511_ENST00000280295_204193354_182926168 length=1387nt
Breakpoint=148nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAA
ATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAA
GGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCAT
GATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGG
TTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAA
TTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGT
TATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTG
TCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAG
AGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTG
AAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAA

>ABI2_PPP1R1C_ENST00000422511_ENST00000409137_204193354_182926168 length=2767nt
Breakpoint=148nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAA
ATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAA
GGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCAT
GATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGG
TTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAA
TTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGT
TATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTG
TCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAG
AGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTG
AAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAATGTTTCCTATGTCTAAATCTATATTTTAAAAATAACCTTTATCATGTAAAATGAGAGAATTGCTGAGTTTATGACAATCTTAGGTATAACCTTTTCTTAAAGAACAAGGCATC
AATCTTTAATTTGTTTCCCTTTCTTGATTTCTCATAAGTTGCAAAATAAAAATAAAAATAATTTCACAAATTGTTCATTATTATTATCCTCCCTACTTGCCCCAGGATTTAAGTACTAACTTTTACTTCCTACTCTTAGACTTTGTATTG
CCAAAGAAATAAAATATGAAAAAGCATAATCACCCAGACCTACCTGCGGAATTGTGGATTATGCTGTAGATATTAGATCATTGAAAGGAACAATATACTACTTAATGAGGAGCCAAAGACAACATTCTACCTGCTGCTCCCTTCAAGCTG
AGGAATGAGTTTAATTGACTTCAAAGTCCCATTATTCTCAAAAGTAGCAAAGGTACAACATGGCTTTGCATGAATCAAAGGAAGGGAACAACAAGAACTTAAAAAAATAGTTTGCAGATGGTTGAACATCTCTTTAATAATTAGAGAAGA
ATATCTTTTCTTTCTTTATTGTTTACAGATACCAACATTTTTCAAAGCCTTGCAGTAGATGAGTGAGTCTCCTGTTACATTTCTCCTGCAGCATATATTCTGTGGATGTGTTTTCCTAAGCAGACTAATTATATGTTGCTCTCTTCTTTT
ACCCTAATGAAACATAGATTTTTCTGTTTTGAATTTGTCACTTGTTTGTTACATTTGTCAAGTGTTTTAAATATTACATTGGTCCTTTATTTGCTTTTGAGAACACCCAATAGTTTAAAAATTAAAATGACATGAAGGTCAATTCTAAGA
CAGGAATGATACTACTAAATCCTGGACTTGCCTATGATAACAAGCTCGAGCTACACACTTTTATTGTCAGAATAAATGGAATATATAGGAAGGAGTTAATTGGAACTGGTTAGTACCTAAATAAGATTTTTCAAAGTAAGTTTTTTGTCG
TATTGGCAGAACAGTGTTAAAAAATAGACATTGTCATCATAAACACCCACAACTATATCTGTAGAAGATAATTTAATGCAATATTCTGGGGAAAATACAGTTGCCAAAATTAATCTCCTTGTTTTCTTTCATTGTGCAATGTGGAGTTAA
ATTTTTTTTCTATTGAGCAGTGTGTGTGTGTGTTTGTGTCTATAATTTATATATGTGCTTGTATACATTTCTATATACACATGTATGTGTATGCAAAATATGTATATATACACATATATATAAAATGTACACTAAATATGTATATATGTA
TATTCATAAAATGTTTTGCTGTATGGAAATAAAAAAGAAGGTTTCTAAAGGAAAGATAGAGAAGAAA

>ABI2_PPP1R1C_ENST00000422511_ENST00000409702_204193354_182926168 length=1074nt
Breakpoint=148nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAA
ATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAA
GGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCC
ACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACC
ACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGC
CAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTT
TTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAA
AAAGGCTATTTTATTGTTATTGCC

>ABI2_PPP1R1C_ENST00000422511_ENST00000452904_204193354_182926168 length=733nt
Breakpoint=148nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAA
ATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAA
GGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCC
ACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGTACACATTGTTCCACATCACTTATAATTAAAGAATAAGCATTTATTTTACAGTGATTCTTCTTTTTAACTATGTAAAAATTTGCATACAT
GTGACTGTTCTAACTTTAATACTGCCAGAGCTTAATCCTTGATGTCCTACTGATAAGGTTTGCATTCTAACAACACATGTAAATAACATCACTTTAAGAGTAAAAAATAAATAGTAAACACATTTAGACATGA

>ABI2_PPP1R1C_ENST00000422511_ENST00000475249_204193354_182926168 length=148nt
Breakpoint=148nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAG

>ABI2_PPP1R1C_ENST00000424558_ENST00000280295_204193354_182926168 length=1476nt
Breakpoint=237nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAG
GAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAA
GGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAA
CAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAG
TATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTG
ATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATT
TAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACC
TATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAG
TTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAA
GCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAA

>ABI2_PPP1R1C_ENST00000424558_ENST00000409137_204193354_182926168 length=2856nt
Breakpoint=237nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAG
GAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAA
GGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGATAA
CAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACATAAG
TATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAAGTG
ATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTAATT
TAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTCACC
TATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTTGAG
TTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGCTAA
GCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAATGTTTCCTATGTCTAAATCTATAT
TTTAAAAATAACCTTTATCATGTAAAATGAGAGAATTGCTGAGTTTATGACAATCTTAGGTATAACCTTTTCTTAAAGAACAAGGCATCAATCTTTAATTTGTTTCCCTTTCTTGATTTCTCATAAGTTGCAAAATAAAAATAAAAATAA
TTTCACAAATTGTTCATTATTATTATCCTCCCTACTTGCCCCAGGATTTAAGTACTAACTTTTACTTCCTACTCTTAGACTTTGTATTGCCAAAGAAATAAAATATGAAAAAGCATAATCACCCAGACCTACCTGCGGAATTGTGGATTA
TGCTGTAGATATTAGATCATTGAAAGGAACAATATACTACTTAATGAGGAGCCAAAGACAACATTCTACCTGCTGCTCCCTTCAAGCTGAGGAATGAGTTTAATTGACTTCAAAGTCCCATTATTCTCAAAAGTAGCAAAGGTACAACAT
GGCTTTGCATGAATCAAAGGAAGGGAACAACAAGAACTTAAAAAAATAGTTTGCAGATGGTTGAACATCTCTTTAATAATTAGAGAAGAATATCTTTTCTTTCTTTATTGTTTACAGATACCAACATTTTTCAAAGCCTTGCAGTAGATG
AGTGAGTCTCCTGTTACATTTCTCCTGCAGCATATATTCTGTGGATGTGTTTTCCTAAGCAGACTAATTATATGTTGCTCTCTTCTTTTACCCTAATGAAACATAGATTTTTCTGTTTTGAATTTGTCACTTGTTTGTTACATTTGTCAA
GTGTTTTAAATATTACATTGGTCCTTTATTTGCTTTTGAGAACACCCAATAGTTTAAAAATTAAAATGACATGAAGGTCAATTCTAAGACAGGAATGATACTACTAAATCCTGGACTTGCCTATGATAACAAGCTCGAGCTACACACTTT
TATTGTCAGAATAAATGGAATATATAGGAAGGAGTTAATTGGAACTGGTTAGTACCTAAATAAGATTTTTCAAAGTAAGTTTTTTGTCGTATTGGCAGAACAGTGTTAAAAAATAGACATTGTCATCATAAACACCCACAACTATATCTG
TAGAAGATAATTTAATGCAATATTCTGGGGAAAATACAGTTGCCAAAATTAATCTCCTTGTTTTCTTTCATTGTGCAATGTGGAGTTAAATTTTTTTTCTATTGAGCAGTGTGTGTGTGTGTTTGTGTCTATAATTTATATATGTGCTTG
TATACATTTCTATATACACATGTATGTGTATGCAAAATATGTATATATACACATATATATAAAATGTACACTAAATATGTATATATGTATATTCATAAAATGTTTTGCTGTATGGAAATAAAAAAGAAGGTTTCTAAAGGAAAGATAGAG
AAGAAA

>ABI2_PPP1R1C_ENST00000424558_ENST00000409702_204193354_182926168 length=1163nt
Breakpoint=237nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAG
GAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAA
GGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTT
CTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGT
GCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTA
GATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTT
TAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCA
TTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCC

>ABI2_PPP1R1C_ENST00000424558_ENST00000452904_204193354_182926168 length=822nt
Breakpoint=237nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAG
GAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGCAAA
GGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGGCTT
CTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTAAGT
ACACATTGTTCCACATCACTTATAATTAAAGAATAAGCATTTATTTTACAGTGATTCTTCTTTTTAACTATGTAAAAATTTGCATACATGTGACTGTTCTAACTTTAATACTGCCAGAGCTTAATCCTTGATGTCCTACTGATAAGGTTT
GCATTCTAACAACACATGTAAATAACATCACTTTAAGAGTAAAAAATAAATAGTAAACACATTTAGACATGA

>ABI2_PPP1R1C_ENST00000424558_ENST00000475249_204193354_182926168 length=237nt
Breakpoint=237nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAG
GAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAG

>ABI2_PPP1R1C_ENST00000430418_ENST00000280295_204193354_182926168 length=1479nt
Breakpoint=240nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAA
GAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGC
AAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGA
TAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACAT
AAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAA
GTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTA
ATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTC
ACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTT
GAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGC
TAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAA

>ABI2_PPP1R1C_ENST00000430418_ENST00000409137_204193354_182926168 length=2859nt
Breakpoint=240nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAA
GAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGC
AAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTGCAAAATGAGTTGA
TAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACTTTAGATATTTTATACAT
AAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGAGTTTAGGTACATTTTAA
GTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATTCCATTGGTCTTGATTTA
ATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCCATCCTGCTAGTAAAGATTTATTCAATTATTTATAATTAATTAAGTGGCTTC
ACCTATATTTCTGTTAATAATCACATTAATTATGTATGACAGGTAGGATTTATGTTATAGATAAGAAAACTAGAGTCCAAAGAAAATAAGTGTCCCCAAATGAACCAATAATCCAACAAACGCTTCCACTAACTAGCTTCTGACCTGTTT
GAGTTGTGATAGATTTTAGAATAAAAAAGCCTATCCTCCTTAGGAGCCATAGACTTTTATTCTTTCTTATACTGTCTTATATATTGACTTAGAGCTAAACTTCCTCCAATTCAGACATAAAGCATAGGCAGATACTTTTGCTAATGAGGC
TAAGCTGGGAAGAAAACCCTGAGTTCTACTTTAATTCTTGGGCATTGACTTCAAACTAAGATGACTTATAAGAAATAAAAGAAGTAAATTTGAAACTTTAATAAAAAAAGTACATGGTTCATTTAAAAATGTTTCCTATGTCTAAATCTA
TATTTTAAAAATAACCTTTATCATGTAAAATGAGAGAATTGCTGAGTTTATGACAATCTTAGGTATAACCTTTTCTTAAAGAACAAGGCATCAATCTTTAATTTGTTTCCCTTTCTTGATTTCTCATAAGTTGCAAAATAAAAATAAAAA
TAATTTCACAAATTGTTCATTATTATTATCCTCCCTACTTGCCCCAGGATTTAAGTACTAACTTTTACTTCCTACTCTTAGACTTTGTATTGCCAAAGAAATAAAATATGAAAAAGCATAATCACCCAGACCTACCTGCGGAATTGTGGA
TTATGCTGTAGATATTAGATCATTGAAAGGAACAATATACTACTTAATGAGGAGCCAAAGACAACATTCTACCTGCTGCTCCCTTCAAGCTGAGGAATGAGTTTAATTGACTTCAAAGTCCCATTATTCTCAAAAGTAGCAAAGGTACAA
CATGGCTTTGCATGAATCAAAGGAAGGGAACAACAAGAACTTAAAAAAATAGTTTGCAGATGGTTGAACATCTCTTTAATAATTAGAGAAGAATATCTTTTCTTTCTTTATTGTTTACAGATACCAACATTTTTCAAAGCCTTGCAGTAG
ATGAGTGAGTCTCCTGTTACATTTCTCCTGCAGCATATATTCTGTGGATGTGTTTTCCTAAGCAGACTAATTATATGTTGCTCTCTTCTTTTACCCTAATGAAACATAGATTTTTCTGTTTTGAATTTGTCACTTGTTTGTTACATTTGT
CAAGTGTTTTAAATATTACATTGGTCCTTTATTTGCTTTTGAGAACACCCAATAGTTTAAAAATTAAAATGACATGAAGGTCAATTCTAAGACAGGAATGATACTACTAAATCCTGGACTTGCCTATGATAACAAGCTCGAGCTACACAC
TTTTATTGTCAGAATAAATGGAATATATAGGAAGGAGTTAATTGGAACTGGTTAGTACCTAAATAAGATTTTTCAAAGTAAGTTTTTTGTCGTATTGGCAGAACAGTGTTAAAAAATAGACATTGTCATCATAAACACCCACAACTATAT
CTGTAGAAGATAATTTAATGCAATATTCTGGGGAAAATACAGTTGCCAAAATTAATCTCCTTGTTTTCTTTCATTGTGCAATGTGGAGTTAAATTTTTTTTCTATTGAGCAGTGTGTGTGTGTGTTTGTGTCTATAATTTATATATGTGC
TTGTATACATTTCTATATACACATGTATGTGTATGCAAAATATGTATATATACACATATATATAAAATGTACACTAAATATGTATATATGTATATTCATAAAATGTTTTGCTGTATGGAAATAAAAAAGAAGGTTTCTAAAGGAAAGATA
GAGAAGAAA

>ABI2_PPP1R1C_ENST00000430418_ENST00000409702_204193354_182926168 length=1166nt
Breakpoint=240nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAA
GAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGC
AAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGG
CTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTA
AGTGCAAAATGAGTTGATAACAACCAGAAGTTGACTTGTTAGTGCTGTGCTTCTACTCGAGCTTGGAAAAATCCCAACACAAAACAAACACCACCTCCGATTCCATCATGATGCCACGTTGCTTTCTACTGGATTACCTCCTGAAGCACT
TTAGATATTTTATACATAAGTATTGACATGTTTTTCAGAAGCTGTTTCTTCACTTATTGCTTTTTTCTAATAATTTTTATTACACCATTTGCCAAGTCCTTCCCTTTGGTTTTAGTTTATTCCTCTCTACAACTAAAAAAGGGATCTTGA
GTTTAGGTACATTTTAAGTGATTCATTTTTAGTTTTTCTAATTCTGGAATCTGAGCCTTCTCTTACAACAGGGAGTCTTTCAAAAACATTTTTTTGTTTCTTTTTCAAATTCCACTGTGTTTATTTATTGCCTTGTTTCTTTTTCAAATT
CCATTGGTCTTGATTTAATTTAGTTCCACAGATTTTACTGATAGTCTACTACCTGCCAACTACTGAATTATGCAGCAGACTTATAAAAATAAAAAGGCTATTTTATTGTTATTGCC

>ABI2_PPP1R1C_ENST00000430418_ENST00000452904_204193354_182926168 length=825nt
Breakpoint=240nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAA
GAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGAAATAGATGACAAGAGGGGGCCCAACACACAAGGGGAATTACAGAATGCATCCCCTAAGC
AAAGGAAGCAGAGTGTGTACACACCACCCACCATAAAAGGGGTTAAGCATCTGAAAGGCCAGAATGAATCAGCATTCCCTGAAGAAGAAGAAGGCACCAATGAAAGAGAGGAGCAGCGGGACCATTAATTACTGGTCTGCAGCAAGAAGG
CTTCTTGGAAATAACTGAACTATTAACTTTTCTGAGTATACCATGGAATTCCACTGCTTGACTTCCAGAAGCATCCTCCATCTCTGCACCCCACACTCATACAGTAGCTATGCACATCCTGGAAGTCTCCTTGACTGAACTTTAGAACTA
AGTACACATTGTTCCACATCACTTATAATTAAAGAATAAGCATTTATTTTACAGTGATTCTTCTTTTTAACTATGTAAAAATTTGCATACATGTGACTGTTCTAACTTTAATACTGCCAGAGCTTAATCCTTGATGTCCTACTGATAAGG
TTTGCATTCTAACAACACATGTAAATAACATCACTTTAAGAGTAAAAAATAAATAGTAAACACATTTAGACATGA

>ABI2_PPP1R1C_ENST00000430418_ENST00000475249_204193354_182926168 length=240nt
Breakpoint=240nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAA
GAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAG


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Fusion Protein Sequence for ABI2_PPP1R1C

check button In-frame Fusion Protein Sequences.

check button N-Truncated Protein (5UTR-3CDS) Sequences

check button C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for ABI2_PPP1R1C


check button TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences
NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button TCGA All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

check button CCLE All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

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Fusion Gene Exprssed Samples for ABI2_PPP1R1C


check buttonRNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDBESCATCGA-LN-A49V-01AABI2

chr2

204193354+PPP1R1C

chr2

204193354

+
ChimerDBESCATCGA-LN-A49VABI2

chr2

204193354+PPP1R1C

chr2

204193354

+
WashUESCATCGA-LN-A49V-01AABI2

chr2

204193354+PPP1R1C

chr2

182926169

+

check buttonDNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrandSV type


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Related Drugs for ABI2_PPP1R1C


check button PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.
PMIDFusion Gene NameDrugStudy Title

check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status