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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:BTN2A1_HIST1H2BC (FusionGDB2 ID:HG11120TG8347)

Fusion Gene Summary for BTN2A1_HIST1H2BC

Fusion gene summary

Fusion gene information	Fusion gene name: BTN2A1_HIST1H2BC
	Fusion gene ID: hg11120tg8347
		Hgene	Tgene
	Gene symbol	BTN2A1	HIST1H2BC
	Gene ID	11120	8347
	Gene name	butyrophilin subfamily 2 member A1	H2B clustered histone 4
	Synonyms	BK14H9.1\|BT2.1\|BTF1\|BTN2.1\|DJ3E1.1	H2B.1\|H2B/l\|H2BC10\|H2BC6\|H2BC7\|H2BC8\|H2BFL\|HIST1H2BC\|dJ221C16.3
	Cytomap	6p22.2	6p22.2
	Type of gene	protein-coding	protein-coding
	Description	butyrophilin subfamily 2 member A1	histone H2B type 1-C/E/F/G/IH2B histone family, member Lhistone 1, H2bchistone H2B.1 Ahistone H2B.lhistone cluster 1 H2B family member chistone cluster 1, H2bc
	Modification date	20240305	20240305
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000312541, ENST00000429381, ENST00000469185, ENST00000541522,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 3 X 5 X 4=60	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 2 X 2 X 3=12
	# samples	5	3
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(5/6010)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(3/1210)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: BTN2A1 [Title/Abstract] AND HIST1H2BC [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	BTN2A1(26463753)-HIST1H2BC(26115363), # samples:1

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Fusion Gene Breakpoints for BTN2A1_HIST1H2BC

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
BTN2A1	chr6	26463753	HIST1H2BC	chr6	26115363
BTN2A1	chr6	26463525	HIST1H2BC	chr6	26115135

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for BTN2A1_HIST1H2BC

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
BTN2A1-HIST1H2BC	Epigenetic Reprogramming / Histone Modifier Dysregulation M3		Promoter swap drives high-level histone H2B type 1-C expression, altering core nucleosomal stoichiometry and chromatin accessibility.		Histone-modifying agents; standard chemotherapy		Solid tumors

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
BTN2A1-HIST1H2BC	Epigenetic Reprogramming / Histone Modifier Dysregulation M3		Promoter swap drives high-level histone H2B type 1-C expression, altering core nucleosomal stoichiometry and chromatin accessibility.		Histone-modifying agents; standard chemotherapy		Solid tumors	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 33633150; Title: CIBERSORT analysis of TCGA and METABRIC identifies subgroups with better outcomes in triple negative breast cancer.; PMID: 36339597; Title: Neutrophil-related genes predict prognosis and response to immune checkpoint inhibitors in bladder cancer.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	HIST1H2BC	GO:0002227	innate immune response in mucosa	12860195
Tgene	HIST1H2BC	GO:0019731	antibacterial humoral response	12860195
Tgene	HIST1H2BC	GO:0050830	defense response to Gram-positive bacterium	12860195
Tgene	HIST1H2BC	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	12860195

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Fusion Genomic Features for BTN2A1_HIST1H2BC

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
BTN2A1	chr6	26463753	+	HIST1H2BC	chr6	26115363	-	2.62e-03	9.97e-01
BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-	9.13e-01	8.69e-02

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for BTN2A1_HIST1H2BC

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000312541	ENST00000314332	BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-
5CDS-3UTR	ENST00000429381	ENST00000314332	BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-
5CDS-3UTR	ENST00000469185	ENST00000314332	BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-
5CDS-3UTR	ENST00000541522	ENST00000314332	BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000312541	ENST00000314332	BTN2A1	chr6	26463753	HIST1H2BC	chr6	26115363	0.00e+00	8.19e-02
ENST00000429381	ENST00000314332	BTN2A1	chr6	26463753	HIST1H2BC	chr6	26115363	0.00e+00	3.96e-02
ENST00000469185	ENST00000314332	BTN2A1	chr6	26463753	HIST1H2BC	chr6	26115363	0.00e+00	4.15e-02
ENST00000541522	ENST00000314332	BTN2A1	chr6	26463753	HIST1H2BC	chr6	26115363	0.00e+00	3.37e-02

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Fusion Protein Retained/Non-Retained Functional Features for BTN2A1_HIST1H2BC

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for BTN2A1_HIST1H2BC

In-frame Fusion Transcript Sequences.

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

>BTN2A1_HIST1H2BC_ENST00000312541_ENST00000314332_26463753_26115363 length=960nt 
 Breakpoint=960nt
ACTCTTGGGACTGTGGAAGCCCAGGAGACCAGATTTCGTTTCCTGCATCTCCAAACATGGCGACCTAGGAGAAGGGGAAGAACAATTTTTTCTCCTCTTTTGGGAAGGTTTGTGTCTAGTAGTGCCTGTGCCCCTGGGCAGATTGGAGAG
AAGAGGGACGACTGGAGAATCGTCGAGAACCAGCGGAGAAAAGAAAAAGCAACGTTTAATTCTAGAAGGCCTCCTGTCCCTGCCTGCTCTGGGTGCTCATGGAATCAGCTGCTGCCCTGCACTTCTCCCGGCCAGCCTCCCTCCTCCTCC
TCCTCCTCAGCCTGTGTGCACTGGTCTCAGCCCAGTTTATTGTCGTGGGGCCCACTGATCCCATCTTGGCCACGGTTGGAGAAAACACTACGTTACGCTGCCATCTGTCACCCGAGAAAAATGCTGAGGACATGGAGGTGCGGTGGTTCC
GGTCTCAGTTCTCCCCCGCAGTGTTTGTGTATAAAGGTGGCAGAGAGAGAACAGAGGAGCAGATGGAGGAGTACCGAGGAAGAACCACCTTTGTGAGCAAAGACATCAGCAGGGGCAGCGTGGCCCTGGTCATACACAACATCACAGCCC
AGGAAAACGGCACCTACCGCTGTTACTTCCAAGAAGGCAGGTCCTACGATGAGGCCATCCTGCACCTCGTAGTGGCAGGACTAGGCTCTAAGCCCCTCATTTCAATGAGGGGCCATGAAGACGGGGGCATCCGGCTGGAGTGCATATCTA
GAGGGTGGTACCCAAAGCCCCTCACAGTGTGGAGGGACCCCTACGGTGGGGTTGCGCCTGCCCTGAAAGAGGTCTCCATGCCTGATGCAGACGGCCTCTTCATGGTCACCACGGCTGTGATCATCAGAGACAAGTCTGTGAGGAACATGT
CCTGCTCTATCAACAACACCCTGCTCGGCCAGAAGAAAGAAAGTGTCATTTTTATTCCAG

>BTN2A1_HIST1H2BC_ENST00000429381_ENST00000314332_26463753_26115363 length=924nt 
 Breakpoint=924nt
CGTTTCCTGCATCTCCAAACATGGCGACCTAGGAGAAGGGGAAGAACAATTTTTTCTCCTCTTTTGGGAAGGTTTGTGTCTAGTAGTGCCTGTGCCCCTGGGCAGATTGGAGAGAAGAGGGACGACTGGAGAATCGTCGAGAACCAGCGG
AGAAAAGAAAAAGCAACGTTTAATTCTAGAAGGCCTCCTGTCCCTGCCTGCTCTGGGTGCTCATGGAATCAGCTGCTGCCCTGCACTTCTCCCGGCCAGCCTCCCTCCTCCTCCTCCTCCTCAGCCTGTGTGCACTGGTCTCAGCCCAGT
TTATTGTCGTGGGGCCCACTGATCCCATCTTGGCCACGGTTGGAGAAAACACTACGTTACGCTGCCATCTGTCACCCGAGAAAAATGCTGAGGACATGGAGGTGCGGTGGTTCCGGTCTCAGTTCTCCCCCGCAGTGTTTGTGTATAAAG
GTGGCAGAGAGAGAACAGAGGAGCAGATGGAGGAGTACCGAGGAAGAACCACCTTTGTGAGCAAAGACATCAGCAGGGGCAGCGTGGCCCTGGTCATACACAACATCACAGCCCAGGAAAACGGCACCTACCGCTGTTACTTCCAAGAAG
GCAGGTCCTACGATGAGGCCATCCTGCACCTCGTAGTGGCAGGACTAGGCTCTAAGCCCCTCATTTCAATGAGGGGCCATGAAGACGGGGGCATCCGGCTGGAGTGCATATCTAGAGGGTGGTACCCAAAGCCCCTCACAGTGTGGAGGG
ACCCCTACGGTGGGGTTGCGCCTGCCCTGAAAGAGGTCTCCATGCCTGATGCAGACGGCCTCTTCATGGTCACCACGGCTGTGATCATCAGAGACAAGTCTGTGAGGAACATGTCCTGCTCTATCAACAACACCCTGCTCGGCCAGAAGA
AAGAAAGTGTCATTTTTATTCCAG

>BTN2A1_HIST1H2BC_ENST00000469185_ENST00000314332_26463753_26115363 length=917nt 
 Breakpoint=917nt
TGCATCTCCAAACATGGCGACCTAGGAGAAGGGGAAGAACAATTTTTTCTCCTCTTTTGGGAAGGTTTGTGTCTAGTAGTGCCTGTGCCCCTGGGCAGATTGGAGAGAAGAGGGACGACTGGAGAATCGTCGAGAACCAGCGGAGAAAAG
AAAAAGCAACGTTTAATTCTAGAAGGCCTCCTGTCCCTGCCTGCTCTGGGTGCTCATGGAATCAGCTGCTGCCCTGCACTTCTCCCGGCCAGCCTCCCTCCTCCTCCTCCTCCTCAGCCTGTGTGCACTGGTCTCAGCCCAGTTTATTGT
CGTGGGGCCCACTGATCCCATCTTGGCCACGGTTGGAGAAAACACTACGTTACGCTGCCATCTGTCACCCGAGAAAAATGCTGAGGACATGGAGGTGCGGTGGTTCCGGTCTCAGTTCTCCCCCGCAGTGTTTGTGTATAAAGGTGGCAG
AGAGAGAACAGAGGAGCAGATGGAGGAGTACCGAGGAAGAACCACCTTTGTGAGCAAAGACATCAGCAGGGGCAGCGTGGCCCTGGTCATACACAACATCACAGCCCAGGAAAACGGCACCTACCGCTGTTACTTCCAAGAAGGCAGGTC
CTACGATGAGGCCATCCTGCACCTCGTAGTGGCAGGACTAGGCTCTAAGCCCCTCATTTCAATGAGGGGCCATGAAGACGGGGGCATCCGGCTGGAGTGCATATCTAGAGGGTGGTACCCAAAGCCCCTCACAGTGTGGAGGGACCCCTA
CGGTGGGGTTGCGCCTGCCCTGAAAGAGGTCTCCATGCCTGATGCAGACGGCCTCTTCATGGTCACCACGGCTGTGATCATCAGAGACAAGTCTGTGAGGAACATGTCCTGCTCTATCAACAACACCCTGCTCGGCCAGAAGAAAGAAAG
TGTCATTTTTATTCCAG

>BTN2A1_HIST1H2BC_ENST00000541522_ENST00000314332_26463753_26115363 length=823nt 
 Breakpoint=823nt
AGACCAGATTTCGTTTCCTGCATCTCCAAACATGGCGACCTAGGAGAAGGGGAAGAACAATTTTTTCTCCTCTTTTGGGAAGGTTTGTGTCTAGTAGTGCCTGTGCCCCTGGGCAGATTGGAGAGAAGAGGGACGACTGGAGAATCGTCG
AGAACCAGCGGAGAAAAGAAAAAGCAACGTTTAATTCTAGAAGCCCAGTTTATTGTCGTGGGGCCCACTGATCCCATCTTGGCCACGGTTGGAGAAAACACTACGTTACGCTGCCATCTGTCACCCGAGAAAAATGCTGAGGACATGGAG
GTGCGGTGGTTCCGGTCTCAGTTCTCCCCCGCAGTGTTTGTGTATAAAGGTGGCAGAGAGAGAACAGAGGAGCAGATGGAGGAGTACCGAGGAAGAACCACCTTTGTGAGCAAAGACATCAGCAGGGGCAGCGTGGCCCTGGTCATACAC
AACATCACAGCCCAGGAAAACGGCACCTACCGCTGTTACTTCCAAGAAGGCAGGTCCTACGATGAGGCCATCCTGCACCTCGTAGTGGCAGGACTAGGCTCTAAGCCCCTCATTTCAATGAGGGGCCATGAAGACGGGGGCATCCGGCTG
GAGTGCATATCTAGAGGGTGGTACCCAAAGCCCCTCACAGTGTGGAGGGACCCCTACGGTGGGGTTGCGCCTGCCCTGAAAGAGGTCTCCATGCCTGATGCAGACGGCCTCTTCATGGTCACCACGGCTGTGATCATCAGAGACAAGTCT
GTGAGGAACATGTCCTGCTCTATCAACAACACCCTGCTCGGCCAGAAGAAAGAAAGTGTCATTTTTATTCCAG

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Fusion Protein Sequence for BTN2A1_HIST1H2BC

In-frame Fusion Protein Sequences.

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for BTN2A1_HIST1H2BC

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for BTN2A1_HIST1H2BC

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		KIRC	TCGA-A3-3313-01A	BTN2A1	chr6	26463753	-	HIST1H2BC	chr6	26115363	-
ChimerDB		KIRC	TCGA-A3-3313-01A	BTN2A1	chr6	26463753	+	HIST1H2BC	chr6	26115363	-
TCGAfusionPortal		KIRC	TCGA-A3-3313-01A	BTN2A1	chr6	26463753	+	HIST1H2BC	chr6	26115363	-
WashU		KIRC	TCGA-A3-3313-01A	BTN2A1	chr6	26463753	+	HIST1H2BC	chr6	26115363	-
cBioPortal	KIRC_TCGA_PAN_CAN_ATLAS_2018	CCRCC	TCGA-A3-3313-01	BTN2A1	chr6	26463525		HIST1H2BC	chr6	26115135

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for BTN2A1_HIST1H2BC

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status