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Fusion gene:C12orf57_HABP4 (FusionGDB2 ID:HG113246TG22927) |
Fusion Gene Summary for C12orf57_HABP4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C12orf57_HABP4 | Fusion gene ID: hg113246tg22927 | Hgene | Tgene | Gene symbol | C12orf57 | HABP4 | Gene ID | 113246 | 22927 |
| Gene name | chromosome 12 open reading frame 57 | hyaluronan binding protein 4 | |
| Synonyms | C10|GRCC10 | IHABP-4|IHABP4|Ki-1/57|SERBP1L | |
| Cytomap | 12p13.31 | 9q22.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein C10gene rich cluster C10likely ortholog of mouse gene rich cluster, C10 | intracellular hyaluronan-binding protein 4chromodomain helicase DNA binding protein 3 interacting proteinintracellular antigen detected by monoclonal antibody Ki-1ki-1/57 intracellular antigen | |
| Modification date | 20240305 | 20240305 | |
| UniProtAcc | . | Q5JVS0 | |
| Ensembl transtripts involved in fusion gene | ENST00000229281, ENST00000537087, ENST00000544681, ENST00000540506, ENST00000542222, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 2 X 2 X 2=8 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 2 X 9 X 8=144 |
| # samples | 2 | 10 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(2/8*10)=1.32192809488736 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(10/144*10)=-0.526068811667588 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: C12orf57 [Title/Abstract] AND HABP4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | C12orf57(7053336)-HABP4(99220660), # samples:1 | ||
| Fusion gene breakpoints across C12orf57 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across HABP4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Breakpoints for C12orf57_HABP4 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for C12orf57_HABP4 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | HABP4 |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | HABP4 | GO:0030578 | PML body organization | 28695742 |
| Tgene | HABP4 | GO:0043392 | negative regulation of DNA binding | 15862299 |
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Fusion Genomic Features for C12orf57_HABP4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + | 9.03e-06 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + | 9.03e-06 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for C12orf57_HABP4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000540506 | ENST00000375249 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| 5UTR-3CDS | ENST00000540506 | ENST00000375251 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000229281 | ENST00000375249 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000229281 | ENST00000375251 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000537087 | ENST00000375249 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000537087 | ENST00000375251 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000544681 | ENST00000375249 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| In-frame | ENST00000544681 | ENST00000375251 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000229281 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 151 | 209 |
| ENST00000229281 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 151 | 314 |
| ENST00000537087 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 340 | 209 |
| ENST00000537087 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 340 | 314 |
| ENST00000544681 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 357 | 209 |
| ENST00000544681 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 357 | 380 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000540506 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 0 | 69 |
| ENST00000540506 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 0 | 275 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000229281 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 5.06e-03 | 9.95e-01 |
| ENST00000229281 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 1.84e-02 | 9.82e-01 |
| ENST00000537087 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 4.74e-03 | 9.95e-01 |
| ENST00000537087 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 1.82e-02 | 9.82e-01 |
| ENST00000544681 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 5.00e-03 | 9.95e-01 |
| ENST00000544681 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 1.91e-02 | 9.81e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000540506 | ENST00000375249 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 0.00e+00 | 6.59e-03 |
| ENST00000540506 | ENST00000375251 | C12orf57 | chr12 | 7053336 | HABP4 | chr9 | 99220660 | 0.00e+00 | 2.63e-02 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
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Fusion Protein Retained/Non-Retained Functional Features for C12orf57_HABP4 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
C12orf57_HABP4_chr12-7053336_chr9-99220660.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 139_182 | 116.33333333333333 | 414.0 | Compositional bias | Basic and acidic residues |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 184_201 | 116.33333333333333 | 414.0 | Compositional bias | Gly residues |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 294_315 | 116.33333333333333 | 414.0 | Compositional bias | Basic and acidic residues |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 404_413 | 116.33333333333333 | 414.0 | Compositional bias | Acidic residues |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 227_320 | 116.33333333333333 | 414.0 | Region | Disordered |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 360_413 | 116.33333333333333 | 414.0 | Region | Disordered |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 40_64 | 116.33333333333333 | 414.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 62_82 | 116.33333333333333 | 414.0 | Compositional bias | Low complexity |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 87_97 | 116.33333333333333 | 414.0 | Compositional bias | Basic and acidic residues |
| Tgene | HABP4 | chr12:7053336 | chr9:99220660 | ENST00000375249 | Q5JVS0 | 0 | 8 | 42_206 | 116.33333333333333 | 414.0 | Region | Disordered |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for C12orf57_HABP4 |
| In-frame Fusion Transcript Sequences. |
>C12orf57_HABP4_ENST00000229281_ENST00000375249_7053336_99220660 length=2342nt Breakpoint=151nt CTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGACGCCCTATGGCGTCCGCCTCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAG GGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAG TTTCCAGATGAAAAACCAGGTGATAGGTTTGATCGAGACAGACCGTTGAGAGGACGTGGAGGCCCGAGAGGGGGTATGCGCGGCAGAGGCAGAGGTGGCCCTGGGAACAGAGTTTTTGACGCTTTTGACCAGAGAGGAAAGCGAGAATTT GAAAGATATGGTGGGAATGACAAAATAGCAGTCAGAACTGAAGACAACATGGGTGGATGTGGAGTTCGAACCTGGGGATCGGGTAAAGATACCAGTGATGTGGAGCCAACTGCACCGATGGAGGAACCCACAGTGGTGGAGGAGTCCCAG GGCACCCCGGAAGAGGAGTCTCCAGCCAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCC ACTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGT CCTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGC CCTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGG GCTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAG GAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACA ATTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTA ATGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCA AATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGT TCTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTG GGCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCC CAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000229281_ENST00000375251_7053336_99220660 length=2027nt Breakpoint=151nt CTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGACGCCCTATGGCGTCCGCCTCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAG GGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAG TTTCCAGATGAAAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAA GCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCC AGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCAC CGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCT CGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAG ACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTT TACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACT ACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTT TCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTT TATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCT GCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTT TTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000537087_ENST00000375249_7053336_99220660 length=2531nt Breakpoint=340nt AGAATTTGTCTAGTAGGCTTTCTGGCTTTTTACCGGAAAGCCCCTCTTATGATGTTTGTTGCCAATGATAGATTGTTTTCACTGTGCAAAAATTATGGGTAGTTTTGGTGGTCTTGATGCAGTTGTAAGCTTGGGGTATGAAGGTTTGGG CCACGCCTGGGCGCTTCCGGCTGCGCCGGATGCTGTTTCCTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGACGCCCTATGGCGTCCGCC TCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAGGGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCC TATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGTTTCCAGATGAAAAACCAGGTGATAGGTTTGATCGAGACAGACCGTTGAGAGGACGTGGAGGCCCGAGAGGGGGTATGCGCGGCAGAGGCAGAGGTGGCCCTGGGAACAGA GTTTTTGACGCTTTTGACCAGAGAGGAAAGCGAGAATTTGAAAGATATGGTGGGAATGACAAAATAGCAGTCAGAACTGAAGACAACATGGGTGGATGTGGAGTTCGAACCTGGGGATCGGGTAAAGATACCAGTGATGTGGAGCCAACT GCACCGATGGAGGAACCCACAGTGGTGGAGGAGTCCCAGGGCACCCCGGAAGAGGAGTCTCCAGCCAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACC AGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATC ACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCA GATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATG TAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAG AGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAG TCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCAC CACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTT AACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGC ACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCA CACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAG TTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000537087_ENST00000375251_7053336_99220660 length=2216nt Breakpoint=340nt AGAATTTGTCTAGTAGGCTTTCTGGCTTTTTACCGGAAAGCCCCTCTTATGATGTTTGTTGCCAATGATAGATTGTTTTCACTGTGCAAAAATTATGGGTAGTTTTGGTGGTCTTGATGCAGTTGTAAGCTTGGGGTATGAAGGTTTGGG CCACGCCTGGGCGCTTCCGGCTGCGCCGGATGCTGTTTCCTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGACGCCCTATGGCGTCCGCC TCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAGGGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCC TATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGTTTCCAGATGAAAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACCAGACCAAAGCCTGAG TTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATCACATCCCAGCTGGAG ATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCAGATGACCCGGAAGAT TTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATGTAAATTTGTTGCACT TTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTC CTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAGTCACAGCTGAGTTTT CGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCACCACTCTGTGACACAG AATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTTAACCTGCCAATCAAA TGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGCACTTATAAGCAGTTT TTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCACACACGCCCGGGAAC ACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTT GAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000544681_ENST00000375249_7053336_99220660 length=2548nt Breakpoint=357nt AGTGTTACAGCTCTTTTAGAATTTGTCTAGTAGGCTTTCTGGCTTTTTACCGGAAAGCCCCTCTTATGATGTTTGTTGCCAATGATAGATTGTTTTCACTGTGCAAAAATTATGGGTAGTTTTGGTGGTCTTGATGCAGTTGTAAGCTTG GGGTATGAAGGTTTGGGCCACGCCTGGGCGCTTCCGGCTGCGCCGGATGCTGTTTCCTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGAC GCCCTATGGCGTCCGCCTCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAGGGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCT ACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGTTTCCAGATGAAAAACCAGGTGATAGGTTTGATCGAGACAGACCGTTGAGAGGACGTGGAGGCCCGAGAGGGGGTATGCGCGGCAGAGGCAGAG GTGGCCCTGGGAACAGAGTTTTTGACGCTTTTGACCAGAGAGGAAAGCGAGAATTTGAAAGATATGGTGGGAATGACAAAATAGCAGTCAGAACTGAAGACAACATGGGTGGATGTGGAGTTCGAACCTGGGGATCGGGTAAAGATACCA GTGATGTGGAGCCAACTGCACCGATGGAGGAACCCACAGTGGTGGAGGAGTCCCAGGGCACCCCGGAAGAGGAGTCTCCAGCCAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAA ATCTTCAAGAACAGACCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGA AACCCGCCAATGACATCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAG ATGTTGCCCCCAACCCAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTT GCTTTTCCCGTGTCATGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGT TTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAA CTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATT GTGTAGCCACTGGCCACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTT CAAAAACCATGTTATTTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATA ACTAGTATTTATTAAGCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAG AGCTGGACCCAGAGCCACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTC TGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000544681_ENST00000375251_7053336_99220660 length=2233nt Breakpoint=357nt AGTGTTACAGCTCTTTTAGAATTTGTCTAGTAGGCTTTCTGGCTTTTTACCGGAAAGCCCCTCTTATGATGTTTGTTGCCAATGATAGATTGTTTTCACTGTGCAAAAATTATGGGTAGTTTTGGTGGTCTTGATGCAGTTGTAAGCTTG GGGTATGAAGGTTTGGGCCACGCCTGGGCGCTTCCGGCTGCGCCGGATGCTGTTTCCTTTCCGCTCCCAGGGGCGTTGGGAACGGTTGTAGGACGTGGCTCTTTATTCGTGAGTTTTCCATTTACCTCCGCTGAACCTAGAGCTTCAGAC GCCCTATGGCGTCCGCCTCGACCCAACCGGCGGCCTTGAGCGCTGAGCAAGCAAAGGGCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCT ACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGTTTCCAGATGAAAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGA CCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACA TCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACC CAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCA TGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATAT AGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGC AGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCC ACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTAT TTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAA GCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGC CACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACAC AGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
>C12orf57_HABP4_ENST00000540506_ENST00000375249_7053336_99220660 length=2191nt Breakpoint=0nt GCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGT TTCCAGATGAAAAACCAGGTGATAGGTTTGATCGAGACAGACCGTTGAGAGGACGTGGAGGCCCGAGAGGGGGTATGCGCGGCAGAGGCAGAGGTGGCCCTGGGAACAGAGTTTTTGACGCTTTTGACCAGAGAGGAAAGCGAGAATTTG AAAGATATGGTGGGAATGACAAAATAGCAGTCAGAACTGAAGACAACATGGGTGGATGTGGAGTTCGAACCTGGGGATCGGGTAAAGATACCAGTGATGTGGAGCCAACTGCACCGATGGAGGAACCCACAGTGGTGGAGGAGTCCCAGG GCACCCCGGAAGAGGAGTCTCCAGCCAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCA CTGTTCCTTCCAAAGCCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTC CTGGGCGTGGAGCCAGAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCC CTGTTTCCCAGCACCGCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGG CTTCTCCAGAGGCTCGAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGG AGGTTGTAAAATAGACTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAA TTGCACTTACTGTTTACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAA TGGTGATTTAAACTACCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAA ATACCGCATCCTTTTCTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTT CTAGAGTTCCTCTTTATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGG GCCTAGGAGGGCCTGCAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCC AGGATCTGTGCTTTTTCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA >C12orf57_HABP4_ENST00000540506_ENST00000375251_7053336_99220660 length=1876nt Breakpoint=0nt GCCAGAAGCGGACTCCTAGAAGAGGGGAGCAGCAAGGATGGAATGACAGCCGTGGGCCGGAGGGGATGCTCGAAAGAGCTGAGCGGAGATCCTACAGGGAATACCGACCCTATGAGACAGAGAGGCAGGCAGACTTCACAGCTGAGAAGT TTCCAGATGAAAAAGTTCCTGAGTTGGAGGTAGAAGAAGAAACCCAAGTTCAAGAGATGACTTTAGATGAGTGGAAAAATCTTCAAGAACAGACCAGACCAAAGCCTGAGTTTAACATCCGGAAACCAGAATCCACTGTTCCTTCCAAAG CCGTGGTGATTCACAAGTCAAAATACAGAGATGATATGGTAAAAGATGACTATGAGGACGATTCCCATGTTTTCCGGAAACCCGCCAATGACATCACATCCCAGCTGGAGATTAATTTTGGTAACCTCCCTCGTCCTGGGCGTGGAGCCA GAGGAGGCACCCGGGGAGGCCGGGGAAGGATCAGGAGGGCAGAGAACTATGGACCCAGAGCAGAAGTGGTGATGCAAGATGTTGCCCCCAACCCAGATGACCCGGAAGATTTCCCTGCGCTGTCTTGAAAGAGCCCTGTTTCCCAGCACC GCGGAGCTGCACTGCACACCTGTGGGGAGACTTTTCCAGCTGGGCCAAGGGAGTCAGACTCTAAGAACAATAGATGTTGCTTTTCCCGTGTCATGTAAATTTGTTGCACTTTTTTGGGCTGAGCTGTTAGAGGGGCTTCTCCAGAGGCTC GAGAGCAGGCCATTTCCCAAGAAGATGAAGAATGGTGACTGTGTTTTTATTGAAGGAATTTCAAATGAAGAATAATGTTTAAAATGTGTATATAGAGATAGTATAGACTCCTCCGCGGAAGCATGGAGGGAAAGGAGGTTGTAAAATAGA CTCCATGGAGACTCTTAGGAAGCAGTAGATTCCCGGGGGCTGTGCCTTTAGCGTTAGAGGAAACACATAGAGCTGGAACTGTTAATGGAAAGCAGTCACAGCTGAGTTTTCGGAGACCAAGAAATTAAAATACAATTGCACTTACTGTTT ACTTGTAAATGTTATCTTCTCTCCTGGAATATTTTGAGTTCTGGTTTTCACTTAACCAATCATTTAAAAATCGCTATTGTGTAGCCACTGGCCACCACTCTGTGACACAGAATCAGAGAAAGCGTTGATTTTTAATGGTGATTTAAACTA CCTCGTGGTTTCTGTGTGTGTGCACACACACATCTAGTGTTTGGGTGGTTTTTAGGAAGAATATTAAGTATGTGACTTCAAAAACCATGTTATTTAACCTGCCAATCAAATGGAAAGGGATCATGGCAAAAGCAAATACCGCATCCTTTT CTTCCGCAGAACTAGAGTCAGAGTTCGGCAGCTGCGTACAAAGGCCTCTGCCCTCGGCTTGAGCAAAAGTTGTAAATAACTAGTATTTATTAAGCACTTATAAGCAGTTTTTCTCACTTAGTCCTGGCTCCAGTTCTAGAGTTCCTCTTT ATTGCTTTTGGTGAAAGTTTGGGGTTGGGGGTACACCTCAGAGGTTCAGTAATTCACCTGGAGTCCCACCCTGAACAGAGCTGGACCCAGAGCCACACACGCCCGGGAACACACACTGTGCTGGGGAGGAAGTGGGCCTAGGAGGGCCTG CAGGTCCAGGCAGCTGTAGAGCTGCTAGAAGCTGGGGTGTTGCTCTCCCCGCTTTCTCATAGACACAGAGGTACTGTCTGCCTGTTGTCACACAGTTCATATGCTCGCTTGAGATGGAATCTGAACCTTGGTCCCAGGATCTGTGCTTTT TCCCACTTTGCCACACTGTCTAAGGTGGCTTTGAACTGGAACCCAAGTGCAAATAAAGGTTGGTATTCGCTCCTGA |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
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Fusion Protein Sequence for C12orf57_HABP4 |
| In-frame Fusion Protein Sequences. |
>C12orf57_HABP4_ENST00000229281_ENST00000375249_7053336_99220660 length=209nt MASASTQPAALSAEQAKGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDIT SQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS >C12orf57_HABP4_ENST00000229281_ENST00000375251_7053336_99220660 length=314nt MASASTQPAALSAEQAKGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRGGPRGGMRGRGRGGPGNRVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGKDTSD VEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDV APNPDDPEDFPALS >C12orf57_HABP4_ENST00000537087_ENST00000375249_7053336_99220660 length=209nt MASASTQPAALSAEQAKGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDIT SQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS >C12orf57_HABP4_ENST00000537087_ENST00000375251_7053336_99220660 length=314nt MASASTQPAALSAEQAKGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRGGPRGGMRGRGRGGPGNRVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGKDTSD VEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDV APNPDDPEDFPALS >C12orf57_HABP4_ENST00000544681_ENST00000375249_7053336_99220660 length=209nt MASASTQPAALSAEQAKGQKRTPRRGEQQGWNDSRGPEGMLERAERRSYREYRPYETERQADFTAEKFPDEKVPELEVEEETQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDIT SQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS >C12orf57_HABP4_ENST00000544681_ENST00000375251_7053336_99220660 length=380nt MKSNSGWLSEPSLPGPPARAANTSQLLGPSRLFASKWRLLGLFGLLLAQVLFLPLGVDPPLRCDHFLRPMGRRANESLNVLIVYHFLFQKGVCQRLQLVQVVLQHLLGVSVGLGHQQSCFMVHHLLQALAEGAPPDAHEALLRLREGDGP DARCHPKLLHHGVGDAGDLPQVVLCPRSDLVEGQCFRGPSSQGHAHPLKQLLLGEEVLVSGEHLSKAQGGVCPRGYGDLHHGLRVLQHPAHQGVARLMKRNHFLFFLGQDLALFGSPCEDALHGVLEVESVHGSVSLPRRVQRSLIADVG DVSPTESWCQLCQTLGVKGAGLGQLQALQVLLKNLPPLLQRGEINEDVPVQSAWPHQSTVQNVSSVRGRQDDDMVCGTHS |
| N-Truncated Protein (5UTR-3CDS) Sequences |
>C12orf57_HABP4_ENST00000540506_ENST00000375249_7053336_99220660 length=69nt MSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP >C12orf57_HABP4_ENST00000540506_ENST00000375251_7053336_99220660 length=275nt MLERAERRSYREYRPYETERQADFTAEKFPDEKPGDRFDRDRPLRGRGGPRGGMRGRGRGGPGNRVFDAFDQRGKREFERYGGNDKIAVRTEDNMGGCGVRTWGSGKDTSDVEPTAPMEEPTVVEESQGTPEEESPAKVPELEVEEETQV QEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSKYRDDMVKDDYEDDSHVFRKPANDITSQLEINFGNLPRPGRGARGGTRGGRGRIRRAENYGPRAEVVMQDVAPNPDDPEDFPALS |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for C12orf57_HABP4 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
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Fusion Gene Exprssed Samples for C12orf57_HABP4 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | FusionScan | GSE122401 | C12orf57 | chr12 | 7053336 | + | HABP4 | chr9 | 99220660 | + |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
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Related Drugs for C12orf57_HABP4 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | HABP4 | Q5JVS0 | DB08818 | Hyaluronic acid | Binder | Small molecule | Approved|Vet_approved |
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