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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene Breakpoints

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness

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Fusion Genomic Features

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Fusion Gene ORF Annotations

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Fusion Protein Retained/Non-Retained Functional Features

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Fusion Transcript Sequences

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Fusion Protein Sequences

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Personalized Fusion Protein Sequences

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Fusion Gene Expressed Samples

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Related Drugs

Fusion gene:AGAP1_ADAMTS2 (FusionGDB2 ID:HG116987TG9509)

Fusion Gene Summary for AGAP1_ADAMTS2

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1_ADAMTS2
Fusion gene ID: hg116987tg9509
HgeneTgene
Gene symbol

AGAP1

ADAMTS2

Gene ID

116987

9509

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1ADAM metallopeptidase with thrombospondin type 1 motif 2
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2ADAM-TS2|ADAMTS-2|ADAMTS-3|EDSDERMS|NPI|PC I-NP|PCI-NP|PCINP|PCPNI|PNPI
Cytomap

2q37.2

5q35.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2A disintegrin and metalloproteinase with thrombospondin motifs 2a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2procollagen I N-proteinaseprocollagen I/II amino propeptide-processing enzymeprocollagen N-endo
Modification date2024030520240403
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304032, ENST00000336665, 
ENST00000409457, ENST00000409538, 
ENST00000428334, 
Fusion gene scores* DoF score* DoF score (Degree of Frequency) = # partners X # break points X # disease types
59 X 23 X 29=39353		* DoF score (Degree of Frequency) = # partners X # break points X # disease types
4 X 6 X 4=96
# samples 10741
** MAII score** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(107/39353*10)=-5.20079091925792
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(41/96*10)=2.09451759878429
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: AGAP1 [Title/Abstract] AND ADAMTS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236653483)-ADAMTS2(178553131), # samples:1

check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ADAMTS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Fusion Gene Breakpoints for AGAP1_ADAMTS2


check button RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbp
AGAP1chr2236653483ADAMTS2chr5178553131


check button DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbpSV type


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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for AGAP1_ADAMTS2


check button To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.
* We have 10 tumorigenic mechanism categories of fusion genes as shown below.
Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand FusionsAberrant Chimeric Transcription Factor / Fusion Transcription Factor ActivityEpigenetic Reprogramming / Histone Modifier DysregulationChromatin Remodeling DysregulationCondensate-Driven Transcriptional Rewiring / LLPPromoter / Enhancer HijackingDominant-Negative AntagonismCell Cycle / Checkpoint Bypass / RNA Processing DysregulationSubcellular Mislocalization / Spatial DysregulationNuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

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Fusion Genomic Features for AGAP1_ADAMTS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AGAP1chr2236653483-ADAMTS2chr5178553131-1.00e+008.66e-07


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).
genomic feature

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Fusion Gene ORF Annotations for AGAP1_ADAMTS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000304032ENST00000251582AGAP1chr2

236653483

-ADAMTS2chr5

178553131

-
In-frameENST00000336665ENST00000251582AGAP1chr2

236653483

-ADAMTS2chr5

178553131

-
In-frameENST00000409457ENST00000251582AGAP1chr2

236653483

-ADAMTS2chr5

178553131

-
In-frameENST00000409538ENST00000251582AGAP1chr2

236653483

-ADAMTS2chr5

178553131

-
In-frameENST00000428334ENST00000251582AGAP1chr2

236653483

-ADAMTS2chr5

178553131

-

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score
ENST00000304032ENST00000251582AGAP1chr2236653483ADAMTS2chr51785531317.84e-049.99e-01
ENST00000336665ENST00000251582AGAP1chr2236653483ADAMTS2chr51785531317.84e-049.99e-01
ENST00000409457ENST00000251582AGAP1chr2236653483ADAMTS2chr51785531317.73e-049.99e-01
ENST00000409538ENST00000251582AGAP1chr2236653483ADAMTS2chr51785531312.24e-041.00e+00
ENST00000428334ENST00000251582AGAP1chr2236653483ADAMTS2chr51785531316.61e-039.93e-01

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

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Fusion Protein Retained/Non-Retained Functional Features for AGAP1_ADAMTS2

check buttonProtein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.
fgviewer annotation
- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).
AGAP1_ADAMTS2_chr2-236653483_chr5-178553131.png
AGAP1_ADAMTS2_chr2-236653483_chr5-178553131.png

- In-frame and retained protein feature among the 13 regional features (texts).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O9545016221059_1097872.33333333333341212.0DomainPLAC
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622914_971872.33333333333341212.0DomainTSP type-1 3
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622975_1029872.33333333333341212.0DomainTSP type-1 4
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O9545016221170_1191872.33333333333341212.0RegionDisordered

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518275_289179.33333333333334858.0Compositional biasLow complexity
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518322_337179.33333333333334858.0Compositional biasBasic and acidic residues
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518422_449179.33333333333334858.0Compositional biasPolar residues
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518504_514179.33333333333334858.0Compositional biasLow complexity
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518524_534179.33333333333334858.0Compositional biasBasic residues
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518346_588179.33333333333334858.0DomainPH
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518609_729179.33333333333334858.0DomainArf-GAP
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ351867_241179.33333333333334858.0DomainGLD
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518267_343179.33333333333334858.0RegionDisordered
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518406_449179.33333333333334858.0RegionDisordered
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518496_547179.33333333333334858.0RegionDisordered
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ351866_276179.33333333333334858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518768_797179.33333333333334858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518801_830179.33333333333334858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236653483chr5:178553131ENST00000304032Q9UPQ3518624_647179.33333333333334858.0Zinc fingerC4-type
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622266_470872.33333333333341212.0DomainPeptidase M12B
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622480_560872.33333333333341212.0DomainNote=Disintegrin
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622561_616872.33333333333341212.0DomainTSP type-1 1
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622854_912872.33333333333341212.0DomainTSP type-1 2
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622691_693872.33333333333341212.0MotifCell attachment site
TgeneADAMTS2chr2:236653483chr5:178553131ENST00000251582O954501622723_851872.33333333333341212.0RegionNote=Spacer


check button - Retained PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Fusion Transcript Sequence for AGAP1_ADAMTS2

check button In-frame Fusion Transcript Sequences.
>AGAP1_ADAMTS2_ENST00000304032_ENST00000251582_236653483_178553131 length=5153nt
Breakpoint=1118nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGC
CCAGGGGTCGGCCCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCC
GCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCT
GGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTT
CGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCA
CTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGGGTCCCAGTTCACCAAGTATGGCTGCCGCCGGAGGCTGGACCACAAGATGGTACACCGTGGCTTCTGTGCCGCCCTCTCGAA
GCCCAAAGCCATCCGCAGAGCGTGCAACCCACAGGAATGCTCCCAGCCAGTGTGGGTCACAGGCGAATGGGAGCCATGTAGCCAGACCTGTGGGCGGACAGGCATGCAGGTGCGCTCCGTGCGCTGCATTCAGCCGCTACACGACAACAC
CACCCGCTCCGTGCACGCCAAGCACTGCAATGACGCCCGGCCCGAGAGCCGCCGGGCCTGCAGCCGCGAGCTCTGCCCTGGTCGTTGGCGAGCCGGGCCCTGGTCCCAGTGCTCAGTAACCTGTGGCAACGGCACCCAGGAGCGGCCAGT
GCTCTGCCGCACCGCGGACGACAGCTTCGGCATCTGCCAGGAGGAGCGTCCTGAGACAGCGAGGACCTGCAGGCTTGGCCCCTGTCCCCGAAACATCTCAGATCCCTCCAAGAAGAGCTACGTAGTTCAGTGGCTGTCCCGCCCGGACCC
CGACTCGCCCATCCGGAAGATCTCGTCAAAGGGCCACTGCCAAGGCGACAAGTCAATATTCTGTAGGATGGAAGTCTTGTCCCGCTATTGCTCCATCCCAGGCTACAACAAGCTGTGCTGCAAGTCCTGTAACCTGTACAACAACCTCAC
CAACGTGGAGGGCAGGATAGAGCCACCGCCTGGGAAGCACAACGACATTGACGTGTTCATGCCTACCCTCCCAGTGCCCACTGTAGCCATGGAGGTGCGGCCATCACCAAGCACCCCCCTGGAGGTCCCTCTCAATGCCTCCAGCACCAA
TGCCACAGAGGATCACCCAGAAACCAATGCCGTAGATGAACCCTACAAAATCCATGGCCTGGAAGATGAAGTCCAGCCACCCAACCTAATCCCTCGACGACCGAGCCCCTATGAAAAGACCAGAAACCAAAGAATCCAAGAGCTCATTGA
TGAGATGCGGAAGAAAGAGATGCTCGGAAAGTTCTAATAAAATGGAAAGATAGCATCCCTAGCATTTTTTTCTTGCTTATAGAGATATTCCATGGGATAGCAAATCCTGTGTCATGGAGATGAAGTCAAAATTCCTGATTCCAAAAGGTT
TTGAGAAAACAAAGAGGGGGAATGACGTAAGAAAGATAGGCATGAGCATGTGGTAACTAGGTTAGCACGTGTGCTTCCCAGCCCAGGAGCGACCAAATACTGTGGTGGCGTCAGGTGTGCAGTGGAGAGGAATATAGAGGCTGTATGGCC
TCCCTCAGTGAGGGCAGGGCAAGAGGGATCACTCTGAGAGAACAAAAATAGGCCCCAAGTTGCTAAGCAGTGATTGGGAACCTTCCTTTCCTTGGCGGAGATGCATGACATTCCCTACCGATCCCCAGACACAGCCTGTGGGACTCTTAG
GAGAAATGGTGATTTACTGAATAACTGACCCGTTGCCGAGATGAGTACAATGAAGTGGAGGTGATGAACTCAAATCGTCTTCCAGGGCCAGGCGGCTGACCGGGGTGAGCGTAGTGGCCCGCTGGGGACCATGGCCGCCCTGACAGCCAC
ACCCACCTGGAGCTGACTTGGTTCTGGCTGTTGCTGCCACTGTGAAATCTGTATCTCTCTCCATCTCTGCTCTACTATCCCCGGCCTTGCCAGACAGTGTTCTTTTTCGGAAGAAGTCTAGATTTTTGCATGAAAAAAACTCAATCTTTA
AAGGTCGACTCAGAACATTTTAAGGAGGCCTCCACTTGGTCTGATGCAGTCTTGCTAATTAAGAACTAAAGGCCTTCTGACCTTCTTGGTGCTCATGCTGTACGGCATCTGAATGTCTCGACCGAGTCTGAGCCGTGCAGCTGTCCTCCA
CCTGCGAAAGTAATGAGAATCCTATCACGGGACATAAGGATAGGTCTAAACAGGGTCCATGCCAAGAAAACAGTGGGGTGCTCTCCCAGGCCTCTCCCCTGTCCACTAACCCTGGCCTTGCCGGCTGCCTTCCAGGCTCTGGGGGAAGAG
CTCCTGCATTCTTCCCTGGCCACCTTGGCTCCAGGGCTCCCCAGAGAGCCTCTTCCCTCCCCAAGTACCTGAGAAAGATGAGAGAGGCACGTGCTCTGCTGGGAAGGTCCAGTGAGCGGTTCAAGGGCCTGGAATCTCCCTACGGCCAAG
TCTAAGGGTTCTGGGATTCTGGGCTTTGTGGGCTTTGCTTGCTTGCTGGGAATGGGCTTTCCCTGTCCCGCCCTGCCCCACCTCGCCTCTGTCTCTCAGAAGCTCCAGAACCCAGCAGTGACCTGCAAAATGTGGCCTCTGATGGGGGCT
TAGGGTGGGAGATGGGGAGAGCCTACATTGTCTTTTGCTCCTTGAAAACTTTAATAGCTCCTATTTTCCAGAGAATGGTGCTTTGTGAGCAACATGCGAGTAAGAGAGAAATAGGAGGAAGGGGGAGTAGGGGCGGATGGGAGAAGAGTG
GCTCATTTTTACCTCTCACTGCCTTGACATTTTGTGAACGTGAAGCTTAAACTTTCTGGGCTTACAAGACCCAGGGGCACGTCAGCTCCTTAGATGGGCTCAGCCTGACACATAATTCTTAAACCTTTCCTGTTTAAGAAACTTCTAGAG
GCTGTGTACTCTCACCAATCCTCTTCGAGAATTTGTTCATGTGTATTTCCCCATTATATGGATGAGGCTCAGGATAACAGCATAGTGGCTACCTTCTACTGAGTTTTGAGGTGCTAATAAGTATGTTTGTCTGAGGCTGCACATGTGGGT
GGCTCTGTGTGTATGATCCAAGGGACAAAATGACGATGTAGGAACCAGCAAGAACGGAATCTGGGCTGATGCTTCAGTCTCCACCTGGGTGATGGCTAGCCTCCCGCCCTCCACCACCGCATCCCACACGTGCTGCGCACTGTCCCCGTG
TCTCCTGGAGAACCAAACTGGAGAAAACCTTTCTGAGTATCTCTCATAGTACCCCTTCCTTAAGAAGATGTGGTTTAGAGCATGTGTGCAATCCTGCCTCTGTAATTAGGAAACGGAGCCCGAGGCTTTCCATTGTTGGTTGAACCCAGG
ACAGCTGGTGCTATTCACAGGCTGAAGAACTGGGCAGTTCTTACTTGGGTCTGTCCTAGGATGTGGAGGAAGTTCAGGACTAACGCTAGGCAGAGAGTATGACTCGGTTTACCCAGCCTAGGGGCCTCTGGATGGGAACACTCCATTCCA
AGATCTCAGCAGAGCAGGGCTTCCTGGCTTGAGGCTGGAAGCCTTTGGGAAGAGGCCCAGCTGGGACATTCCCTGGGCACCTGTCTTCCGCTGAAGGGAGCAAGGTGCCCTCTGGGACTGACAGCCATGACCCTCTGTGCCATCCTCAAT
CCTTGAGCCATATATCAAGAGTCCTCTAGAGCCGGATGGTCCTCAAAAGTCTGTCCAAGGAATGCCAACGTTCACCGGGCTCTGAGAAACGACGCAAATCTCTGAGCTGGGGACCACTTGGAGAACCGGCTTAGTAACAGTCCTGATCTT
CGCAAGCCAGCTTCTTCTGCATCTGAGGGGCTCCTGGCGCCCAGAGGAGGCAGACAGATGTCTTCTAGCTGAGTTTCTAACCGCATGATGAGACTCAGACCTTCCGCTGCACTAGAAAATCTGCAACAGTGTCCCTGAGTCACTTCTCCT
TAGTGGGCAGACTCGTGTTAGATTTGTGGAACCCAGCTCTCTGATTTACTCCTTTTGGAAAACCCATGGAATTTCATGTATAAGGCTTTCATTTGTATTTTAAGGTTTTTCTGTTTGTTTTGAGTATATACATGGTGCTCAATAGCAACA
TCTTAGCAGATGAAGCAGTTTATGATTCCACTCCCTCCTGTATGACAGGTAGCCACTATACTGAATCAAGGTGCTGAACTCAAATCACAAAATTCTGGCTTACCGATACAACAACCAATACATCTTTGTTCTGTAATGTAAAATTTGACT
CCTTACTTTTATAACTTATTAAAGTTAAAATGTCTGTGTTTTTGCAAATCATG

>AGAP1_ADAMTS2_ENST00000336665_ENST00000251582_236653483_178553131 length=5153nt
Breakpoint=1118nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGC
CCAGGGGTCGGCCCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCC
GCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCT
GGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTT
CGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCA
CTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGGGTCCCAGTTCACCAAGTATGGCTGCCGCCGGAGGCTGGACCACAAGATGGTACACCGTGGCTTCTGTGCCGCCCTCTCGAA
GCCCAAAGCCATCCGCAGAGCGTGCAACCCACAGGAATGCTCCCAGCCAGTGTGGGTCACAGGCGAATGGGAGCCATGTAGCCAGACCTGTGGGCGGACAGGCATGCAGGTGCGCTCCGTGCGCTGCATTCAGCCGCTACACGACAACAC
CACCCGCTCCGTGCACGCCAAGCACTGCAATGACGCCCGGCCCGAGAGCCGCCGGGCCTGCAGCCGCGAGCTCTGCCCTGGTCGTTGGCGAGCCGGGCCCTGGTCCCAGTGCTCAGTAACCTGTGGCAACGGCACCCAGGAGCGGCCAGT
GCTCTGCCGCACCGCGGACGACAGCTTCGGCATCTGCCAGGAGGAGCGTCCTGAGACAGCGAGGACCTGCAGGCTTGGCCCCTGTCCCCGAAACATCTCAGATCCCTCCAAGAAGAGCTACGTAGTTCAGTGGCTGTCCCGCCCGGACCC
CGACTCGCCCATCCGGAAGATCTCGTCAAAGGGCCACTGCCAAGGCGACAAGTCAATATTCTGTAGGATGGAAGTCTTGTCCCGCTATTGCTCCATCCCAGGCTACAACAAGCTGTGCTGCAAGTCCTGTAACCTGTACAACAACCTCAC
CAACGTGGAGGGCAGGATAGAGCCACCGCCTGGGAAGCACAACGACATTGACGTGTTCATGCCTACCCTCCCAGTGCCCACTGTAGCCATGGAGGTGCGGCCATCACCAAGCACCCCCCTGGAGGTCCCTCTCAATGCCTCCAGCACCAA
TGCCACAGAGGATCACCCAGAAACCAATGCCGTAGATGAACCCTACAAAATCCATGGCCTGGAAGATGAAGTCCAGCCACCCAACCTAATCCCTCGACGACCGAGCCCCTATGAAAAGACCAGAAACCAAAGAATCCAAGAGCTCATTGA
TGAGATGCGGAAGAAAGAGATGCTCGGAAAGTTCTAATAAAATGGAAAGATAGCATCCCTAGCATTTTTTTCTTGCTTATAGAGATATTCCATGGGATAGCAAATCCTGTGTCATGGAGATGAAGTCAAAATTCCTGATTCCAAAAGGTT
TTGAGAAAACAAAGAGGGGGAATGACGTAAGAAAGATAGGCATGAGCATGTGGTAACTAGGTTAGCACGTGTGCTTCCCAGCCCAGGAGCGACCAAATACTGTGGTGGCGTCAGGTGTGCAGTGGAGAGGAATATAGAGGCTGTATGGCC
TCCCTCAGTGAGGGCAGGGCAAGAGGGATCACTCTGAGAGAACAAAAATAGGCCCCAAGTTGCTAAGCAGTGATTGGGAACCTTCCTTTCCTTGGCGGAGATGCATGACATTCCCTACCGATCCCCAGACACAGCCTGTGGGACTCTTAG
GAGAAATGGTGATTTACTGAATAACTGACCCGTTGCCGAGATGAGTACAATGAAGTGGAGGTGATGAACTCAAATCGTCTTCCAGGGCCAGGCGGCTGACCGGGGTGAGCGTAGTGGCCCGCTGGGGACCATGGCCGCCCTGACAGCCAC
ACCCACCTGGAGCTGACTTGGTTCTGGCTGTTGCTGCCACTGTGAAATCTGTATCTCTCTCCATCTCTGCTCTACTATCCCCGGCCTTGCCAGACAGTGTTCTTTTTCGGAAGAAGTCTAGATTTTTGCATGAAAAAAACTCAATCTTTA
AAGGTCGACTCAGAACATTTTAAGGAGGCCTCCACTTGGTCTGATGCAGTCTTGCTAATTAAGAACTAAAGGCCTTCTGACCTTCTTGGTGCTCATGCTGTACGGCATCTGAATGTCTCGACCGAGTCTGAGCCGTGCAGCTGTCCTCCA
CCTGCGAAAGTAATGAGAATCCTATCACGGGACATAAGGATAGGTCTAAACAGGGTCCATGCCAAGAAAACAGTGGGGTGCTCTCCCAGGCCTCTCCCCTGTCCACTAACCCTGGCCTTGCCGGCTGCCTTCCAGGCTCTGGGGGAAGAG
CTCCTGCATTCTTCCCTGGCCACCTTGGCTCCAGGGCTCCCCAGAGAGCCTCTTCCCTCCCCAAGTACCTGAGAAAGATGAGAGAGGCACGTGCTCTGCTGGGAAGGTCCAGTGAGCGGTTCAAGGGCCTGGAATCTCCCTACGGCCAAG
TCTAAGGGTTCTGGGATTCTGGGCTTTGTGGGCTTTGCTTGCTTGCTGGGAATGGGCTTTCCCTGTCCCGCCCTGCCCCACCTCGCCTCTGTCTCTCAGAAGCTCCAGAACCCAGCAGTGACCTGCAAAATGTGGCCTCTGATGGGGGCT
TAGGGTGGGAGATGGGGAGAGCCTACATTGTCTTTTGCTCCTTGAAAACTTTAATAGCTCCTATTTTCCAGAGAATGGTGCTTTGTGAGCAACATGCGAGTAAGAGAGAAATAGGAGGAAGGGGGAGTAGGGGCGGATGGGAGAAGAGTG
GCTCATTTTTACCTCTCACTGCCTTGACATTTTGTGAACGTGAAGCTTAAACTTTCTGGGCTTACAAGACCCAGGGGCACGTCAGCTCCTTAGATGGGCTCAGCCTGACACATAATTCTTAAACCTTTCCTGTTTAAGAAACTTCTAGAG
GCTGTGTACTCTCACCAATCCTCTTCGAGAATTTGTTCATGTGTATTTCCCCATTATATGGATGAGGCTCAGGATAACAGCATAGTGGCTACCTTCTACTGAGTTTTGAGGTGCTAATAAGTATGTTTGTCTGAGGCTGCACATGTGGGT
GGCTCTGTGTGTATGATCCAAGGGACAAAATGACGATGTAGGAACCAGCAAGAACGGAATCTGGGCTGATGCTTCAGTCTCCACCTGGGTGATGGCTAGCCTCCCGCCCTCCACCACCGCATCCCACACGTGCTGCGCACTGTCCCCGTG
TCTCCTGGAGAACCAAACTGGAGAAAACCTTTCTGAGTATCTCTCATAGTACCCCTTCCTTAAGAAGATGTGGTTTAGAGCATGTGTGCAATCCTGCCTCTGTAATTAGGAAACGGAGCCCGAGGCTTTCCATTGTTGGTTGAACCCAGG
ACAGCTGGTGCTATTCACAGGCTGAAGAACTGGGCAGTTCTTACTTGGGTCTGTCCTAGGATGTGGAGGAAGTTCAGGACTAACGCTAGGCAGAGAGTATGACTCGGTTTACCCAGCCTAGGGGCCTCTGGATGGGAACACTCCATTCCA
AGATCTCAGCAGAGCAGGGCTTCCTGGCTTGAGGCTGGAAGCCTTTGGGAAGAGGCCCAGCTGGGACATTCCCTGGGCACCTGTCTTCCGCTGAAGGGAGCAAGGTGCCCTCTGGGACTGACAGCCATGACCCTCTGTGCCATCCTCAAT
CCTTGAGCCATATATCAAGAGTCCTCTAGAGCCGGATGGTCCTCAAAAGTCTGTCCAAGGAATGCCAACGTTCACCGGGCTCTGAGAAACGACGCAAATCTCTGAGCTGGGGACCACTTGGAGAACCGGCTTAGTAACAGTCCTGATCTT
CGCAAGCCAGCTTCTTCTGCATCTGAGGGGCTCCTGGCGCCCAGAGGAGGCAGACAGATGTCTTCTAGCTGAGTTTCTAACCGCATGATGAGACTCAGACCTTCCGCTGCACTAGAAAATCTGCAACAGTGTCCCTGAGTCACTTCTCCT
TAGTGGGCAGACTCGTGTTAGATTTGTGGAACCCAGCTCTCTGATTTACTCCTTTTGGAAAACCCATGGAATTTCATGTATAAGGCTTTCATTTGTATTTTAAGGTTTTTCTGTTTGTTTTGAGTATATACATGGTGCTCAATAGCAACA
TCTTAGCAGATGAAGCAGTTTATGATTCCACTCCCTCCTGTATGACAGGTAGCCACTATACTGAATCAAGGTGCTGAACTCAAATCACAAAATTCTGGCTTACCGATACAACAACCAATACATCTTTGTTCTGTAATGTAAAATTTGACT
CCTTACTTTTATAACTTATTAAAGTTAAAATGTCTGTGTTTTTGCAAATCATG

>AGAP1_ADAMTS2_ENST00000409457_ENST00000251582_236653483_178553131 length=5171nt
Breakpoint=1136nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGA
GCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGCAAGCCTCCTTCG
GGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCAT
GAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCGGGAGCACGTCAT
CGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAG
TTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGGGTCCCAGTTCACCAAGTATGGCTGCCGCCGGAGGCTGGACCACAAGATGGTACACCGTGGCTT
CTGTGCCGCCCTCTCGAAGCCCAAAGCCATCCGCAGAGCGTGCAACCCACAGGAATGCTCCCAGCCAGTGTGGGTCACAGGCGAATGGGAGCCATGTAGCCAGACCTGTGGGCGGACAGGCATGCAGGTGCGCTCCGTGCGCTGCATTCA
GCCGCTACACGACAACACCACCCGCTCCGTGCACGCCAAGCACTGCAATGACGCCCGGCCCGAGAGCCGCCGGGCCTGCAGCCGCGAGCTCTGCCCTGGTCGTTGGCGAGCCGGGCCCTGGTCCCAGTGCTCAGTAACCTGTGGCAACGG
CACCCAGGAGCGGCCAGTGCTCTGCCGCACCGCGGACGACAGCTTCGGCATCTGCCAGGAGGAGCGTCCTGAGACAGCGAGGACCTGCAGGCTTGGCCCCTGTCCCCGAAACATCTCAGATCCCTCCAAGAAGAGCTACGTAGTTCAGTG
GCTGTCCCGCCCGGACCCCGACTCGCCCATCCGGAAGATCTCGTCAAAGGGCCACTGCCAAGGCGACAAGTCAATATTCTGTAGGATGGAAGTCTTGTCCCGCTATTGCTCCATCCCAGGCTACAACAAGCTGTGCTGCAAGTCCTGTAA
CCTGTACAACAACCTCACCAACGTGGAGGGCAGGATAGAGCCACCGCCTGGGAAGCACAACGACATTGACGTGTTCATGCCTACCCTCCCAGTGCCCACTGTAGCCATGGAGGTGCGGCCATCACCAAGCACCCCCCTGGAGGTCCCTCT
CAATGCCTCCAGCACCAATGCCACAGAGGATCACCCAGAAACCAATGCCGTAGATGAACCCTACAAAATCCATGGCCTGGAAGATGAAGTCCAGCCACCCAACCTAATCCCTCGACGACCGAGCCCCTATGAAAAGACCAGAAACCAAAG
AATCCAAGAGCTCATTGATGAGATGCGGAAGAAAGAGATGCTCGGAAAGTTCTAATAAAATGGAAAGATAGCATCCCTAGCATTTTTTTCTTGCTTATAGAGATATTCCATGGGATAGCAAATCCTGTGTCATGGAGATGAAGTCAAAAT
TCCTGATTCCAAAAGGTTTTGAGAAAACAAAGAGGGGGAATGACGTAAGAAAGATAGGCATGAGCATGTGGTAACTAGGTTAGCACGTGTGCTTCCCAGCCCAGGAGCGACCAAATACTGTGGTGGCGTCAGGTGTGCAGTGGAGAGGAA
TATAGAGGCTGTATGGCCTCCCTCAGTGAGGGCAGGGCAAGAGGGATCACTCTGAGAGAACAAAAATAGGCCCCAAGTTGCTAAGCAGTGATTGGGAACCTTCCTTTCCTTGGCGGAGATGCATGACATTCCCTACCGATCCCCAGACAC
AGCCTGTGGGACTCTTAGGAGAAATGGTGATTTACTGAATAACTGACCCGTTGCCGAGATGAGTACAATGAAGTGGAGGTGATGAACTCAAATCGTCTTCCAGGGCCAGGCGGCTGACCGGGGTGAGCGTAGTGGCCCGCTGGGGACCAT
GGCCGCCCTGACAGCCACACCCACCTGGAGCTGACTTGGTTCTGGCTGTTGCTGCCACTGTGAAATCTGTATCTCTCTCCATCTCTGCTCTACTATCCCCGGCCTTGCCAGACAGTGTTCTTTTTCGGAAGAAGTCTAGATTTTTGCATG
AAAAAAACTCAATCTTTAAAGGTCGACTCAGAACATTTTAAGGAGGCCTCCACTTGGTCTGATGCAGTCTTGCTAATTAAGAACTAAAGGCCTTCTGACCTTCTTGGTGCTCATGCTGTACGGCATCTGAATGTCTCGACCGAGTCTGAG
CCGTGCAGCTGTCCTCCACCTGCGAAAGTAATGAGAATCCTATCACGGGACATAAGGATAGGTCTAAACAGGGTCCATGCCAAGAAAACAGTGGGGTGCTCTCCCAGGCCTCTCCCCTGTCCACTAACCCTGGCCTTGCCGGCTGCCTTC
CAGGCTCTGGGGGAAGAGCTCCTGCATTCTTCCCTGGCCACCTTGGCTCCAGGGCTCCCCAGAGAGCCTCTTCCCTCCCCAAGTACCTGAGAAAGATGAGAGAGGCACGTGCTCTGCTGGGAAGGTCCAGTGAGCGGTTCAAGGGCCTGG
AATCTCCCTACGGCCAAGTCTAAGGGTTCTGGGATTCTGGGCTTTGTGGGCTTTGCTTGCTTGCTGGGAATGGGCTTTCCCTGTCCCGCCCTGCCCCACCTCGCCTCTGTCTCTCAGAAGCTCCAGAACCCAGCAGTGACCTGCAAAATG
TGGCCTCTGATGGGGGCTTAGGGTGGGAGATGGGGAGAGCCTACATTGTCTTTTGCTCCTTGAAAACTTTAATAGCTCCTATTTTCCAGAGAATGGTGCTTTGTGAGCAACATGCGAGTAAGAGAGAAATAGGAGGAAGGGGGAGTAGGG
GCGGATGGGAGAAGAGTGGCTCATTTTTACCTCTCACTGCCTTGACATTTTGTGAACGTGAAGCTTAAACTTTCTGGGCTTACAAGACCCAGGGGCACGTCAGCTCCTTAGATGGGCTCAGCCTGACACATAATTCTTAAACCTTTCCTG
TTTAAGAAACTTCTAGAGGCTGTGTACTCTCACCAATCCTCTTCGAGAATTTGTTCATGTGTATTTCCCCATTATATGGATGAGGCTCAGGATAACAGCATAGTGGCTACCTTCTACTGAGTTTTGAGGTGCTAATAAGTATGTTTGTCT
GAGGCTGCACATGTGGGTGGCTCTGTGTGTATGATCCAAGGGACAAAATGACGATGTAGGAACCAGCAAGAACGGAATCTGGGCTGATGCTTCAGTCTCCACCTGGGTGATGGCTAGCCTCCCGCCCTCCACCACCGCATCCCACACGTG
CTGCGCACTGTCCCCGTGTCTCCTGGAGAACCAAACTGGAGAAAACCTTTCTGAGTATCTCTCATAGTACCCCTTCCTTAAGAAGATGTGGTTTAGAGCATGTGTGCAATCCTGCCTCTGTAATTAGGAAACGGAGCCCGAGGCTTTCCA
TTGTTGGTTGAACCCAGGACAGCTGGTGCTATTCACAGGCTGAAGAACTGGGCAGTTCTTACTTGGGTCTGTCCTAGGATGTGGAGGAAGTTCAGGACTAACGCTAGGCAGAGAGTATGACTCGGTTTACCCAGCCTAGGGGCCTCTGGA
TGGGAACACTCCATTCCAAGATCTCAGCAGAGCAGGGCTTCCTGGCTTGAGGCTGGAAGCCTTTGGGAAGAGGCCCAGCTGGGACATTCCCTGGGCACCTGTCTTCCGCTGAAGGGAGCAAGGTGCCCTCTGGGACTGACAGCCATGACC
CTCTGTGCCATCCTCAATCCTTGAGCCATATATCAAGAGTCCTCTAGAGCCGGATGGTCCTCAAAAGTCTGTCCAAGGAATGCCAACGTTCACCGGGCTCTGAGAAACGACGCAAATCTCTGAGCTGGGGACCACTTGGAGAACCGGCTT
AGTAACAGTCCTGATCTTCGCAAGCCAGCTTCTTCTGCATCTGAGGGGCTCCTGGCGCCCAGAGGAGGCAGACAGATGTCTTCTAGCTGAGTTTCTAACCGCATGATGAGACTCAGACCTTCCGCTGCACTAGAAAATCTGCAACAGTGT
CCCTGAGTCACTTCTCCTTAGTGGGCAGACTCGTGTTAGATTTGTGGAACCCAGCTCTCTGATTTACTCCTTTTGGAAAACCCATGGAATTTCATGTATAAGGCTTTCATTTGTATTTTAAGGTTTTTCTGTTTGTTTTGAGTATATACA
TGGTGCTCAATAGCAACATCTTAGCAGATGAAGCAGTTTATGATTCCACTCCCTCCTGTATGACAGGTAGCCACTATACTGAATCAAGGTGCTGAACTCAAATCACAAAATTCTGGCTTACCGATACAACAACCAATACATCTTTGTTCT
GTAATGTAAAATTTGACTCCTTACTTTTATAACTTATTAAAGTTAAAATGTCTGTGTTTTTGCAAATCATG

>AGAP1_ADAMTS2_ENST00000409538_ENST00000251582_236653483_178553131 length=5864nt
Breakpoint=1829nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCCAGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCAC
GGGCCCCGCGTCGTAGACAATGAAGCCGCGGGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCCCGCCGGCCCATGGCTCGGCGCCCCGGGCCC
GGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCCGCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGCGGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCAT
GGTCAGGAAGGAGCAGCTGGCCGCGCCGGGCTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGAGGCGGAGGGCGCCGAGGAACCGGAGGGTCC
CCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACTGGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCAAGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCC
GTGCGACGAGGCCGCGGCCGGGACCACCCTGGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGACCTGGAGCGTTGGGAACGCAGTAAGAGCAA
GAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGGGGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGGCTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCC
GGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCT
GCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGGGTCCCAGTTCACCAAGTATGGCTGCCGCCGGAGGCTGGACCACAAGATGGTACACCGTGGCTTCTGTGCCGCCCTCTCGAAGCCCAAAGCCATCCGCAGAGCGTGCAACCCACAGGAATG
CTCCCAGCCAGTGTGGGTCACAGGCGAATGGGAGCCATGTAGCCAGACCTGTGGGCGGACAGGCATGCAGGTGCGCTCCGTGCGCTGCATTCAGCCGCTACACGACAACACCACCCGCTCCGTGCACGCCAAGCACTGCAATGACGCCCG
GCCCGAGAGCCGCCGGGCCTGCAGCCGCGAGCTCTGCCCTGGTCGTTGGCGAGCCGGGCCCTGGTCCCAGTGCTCAGTAACCTGTGGCAACGGCACCCAGGAGCGGCCAGTGCTCTGCCGCACCGCGGACGACAGCTTCGGCATCTGCCA
GGAGGAGCGTCCTGAGACAGCGAGGACCTGCAGGCTTGGCCCCTGTCCCCGAAACATCTCAGATCCCTCCAAGAAGAGCTACGTAGTTCAGTGGCTGTCCCGCCCGGACCCCGACTCGCCCATCCGGAAGATCTCGTCAAAGGGCCACTG
CCAAGGCGACAAGTCAATATTCTGTAGGATGGAAGTCTTGTCCCGCTATTGCTCCATCCCAGGCTACAACAAGCTGTGCTGCAAGTCCTGTAACCTGTACAACAACCTCACCAACGTGGAGGGCAGGATAGAGCCACCGCCTGGGAAGCA
CAACGACATTGACGTGTTCATGCCTACCCTCCCAGTGCCCACTGTAGCCATGGAGGTGCGGCCATCACCAAGCACCCCCCTGGAGGTCCCTCTCAATGCCTCCAGCACCAATGCCACAGAGGATCACCCAGAAACCAATGCCGTAGATGA
ACCCTACAAAATCCATGGCCTGGAAGATGAAGTCCAGCCACCCAACCTAATCCCTCGACGACCGAGCCCCTATGAAAAGACCAGAAACCAAAGAATCCAAGAGCTCATTGATGAGATGCGGAAGAAAGAGATGCTCGGAAAGTTCTAATA
AAATGGAAAGATAGCATCCCTAGCATTTTTTTCTTGCTTATAGAGATATTCCATGGGATAGCAAATCCTGTGTCATGGAGATGAAGTCAAAATTCCTGATTCCAAAAGGTTTTGAGAAAACAAAGAGGGGGAATGACGTAAGAAAGATAG
GCATGAGCATGTGGTAACTAGGTTAGCACGTGTGCTTCCCAGCCCAGGAGCGACCAAATACTGTGGTGGCGTCAGGTGTGCAGTGGAGAGGAATATAGAGGCTGTATGGCCTCCCTCAGTGAGGGCAGGGCAAGAGGGATCACTCTGAGA
GAACAAAAATAGGCCCCAAGTTGCTAAGCAGTGATTGGGAACCTTCCTTTCCTTGGCGGAGATGCATGACATTCCCTACCGATCCCCAGACACAGCCTGTGGGACTCTTAGGAGAAATGGTGATTTACTGAATAACTGACCCGTTGCCGA
GATGAGTACAATGAAGTGGAGGTGATGAACTCAAATCGTCTTCCAGGGCCAGGCGGCTGACCGGGGTGAGCGTAGTGGCCCGCTGGGGACCATGGCCGCCCTGACAGCCACACCCACCTGGAGCTGACTTGGTTCTGGCTGTTGCTGCCA
CTGTGAAATCTGTATCTCTCTCCATCTCTGCTCTACTATCCCCGGCCTTGCCAGACAGTGTTCTTTTTCGGAAGAAGTCTAGATTTTTGCATGAAAAAAACTCAATCTTTAAAGGTCGACTCAGAACATTTTAAGGAGGCCTCCACTTGG
TCTGATGCAGTCTTGCTAATTAAGAACTAAAGGCCTTCTGACCTTCTTGGTGCTCATGCTGTACGGCATCTGAATGTCTCGACCGAGTCTGAGCCGTGCAGCTGTCCTCCACCTGCGAAAGTAATGAGAATCCTATCACGGGACATAAGG
ATAGGTCTAAACAGGGTCCATGCCAAGAAAACAGTGGGGTGCTCTCCCAGGCCTCTCCCCTGTCCACTAACCCTGGCCTTGCCGGCTGCCTTCCAGGCTCTGGGGGAAGAGCTCCTGCATTCTTCCCTGGCCACCTTGGCTCCAGGGCTC
CCCAGAGAGCCTCTTCCCTCCCCAAGTACCTGAGAAAGATGAGAGAGGCACGTGCTCTGCTGGGAAGGTCCAGTGAGCGGTTCAAGGGCCTGGAATCTCCCTACGGCCAAGTCTAAGGGTTCTGGGATTCTGGGCTTTGTGGGCTTTGCT
TGCTTGCTGGGAATGGGCTTTCCCTGTCCCGCCCTGCCCCACCTCGCCTCTGTCTCTCAGAAGCTCCAGAACCCAGCAGTGACCTGCAAAATGTGGCCTCTGATGGGGGCTTAGGGTGGGAGATGGGGAGAGCCTACATTGTCTTTTGCT
CCTTGAAAACTTTAATAGCTCCTATTTTCCAGAGAATGGTGCTTTGTGAGCAACATGCGAGTAAGAGAGAAATAGGAGGAAGGGGGAGTAGGGGCGGATGGGAGAAGAGTGGCTCATTTTTACCTCTCACTGCCTTGACATTTTGTGAAC
GTGAAGCTTAAACTTTCTGGGCTTACAAGACCCAGGGGCACGTCAGCTCCTTAGATGGGCTCAGCCTGACACATAATTCTTAAACCTTTCCTGTTTAAGAAACTTCTAGAGGCTGTGTACTCTCACCAATCCTCTTCGAGAATTTGTTCA
TGTGTATTTCCCCATTATATGGATGAGGCTCAGGATAACAGCATAGTGGCTACCTTCTACTGAGTTTTGAGGTGCTAATAAGTATGTTTGTCTGAGGCTGCACATGTGGGTGGCTCTGTGTGTATGATCCAAGGGACAAAATGACGATGT
AGGAACCAGCAAGAACGGAATCTGGGCTGATGCTTCAGTCTCCACCTGGGTGATGGCTAGCCTCCCGCCCTCCACCACCGCATCCCACACGTGCTGCGCACTGTCCCCGTGTCTCCTGGAGAACCAAACTGGAGAAAACCTTTCTGAGTA
TCTCTCATAGTACCCCTTCCTTAAGAAGATGTGGTTTAGAGCATGTGTGCAATCCTGCCTCTGTAATTAGGAAACGGAGCCCGAGGCTTTCCATTGTTGGTTGAACCCAGGACAGCTGGTGCTATTCACAGGCTGAAGAACTGGGCAGTT
CTTACTTGGGTCTGTCCTAGGATGTGGAGGAAGTTCAGGACTAACGCTAGGCAGAGAGTATGACTCGGTTTACCCAGCCTAGGGGCCTCTGGATGGGAACACTCCATTCCAAGATCTCAGCAGAGCAGGGCTTCCTGGCTTGAGGCTGGA
AGCCTTTGGGAAGAGGCCCAGCTGGGACATTCCCTGGGCACCTGTCTTCCGCTGAAGGGAGCAAGGTGCCCTCTGGGACTGACAGCCATGACCCTCTGTGCCATCCTCAATCCTTGAGCCATATATCAAGAGTCCTCTAGAGCCGGATGG
TCCTCAAAAGTCTGTCCAAGGAATGCCAACGTTCACCGGGCTCTGAGAAACGACGCAAATCTCTGAGCTGGGGACCACTTGGAGAACCGGCTTAGTAACAGTCCTGATCTTCGCAAGCCAGCTTCTTCTGCATCTGAGGGGCTCCTGGCG
CCCAGAGGAGGCAGACAGATGTCTTCTAGCTGAGTTTCTAACCGCATGATGAGACTCAGACCTTCCGCTGCACTAGAAAATCTGCAACAGTGTCCCTGAGTCACTTCTCCTTAGTGGGCAGACTCGTGTTAGATTTGTGGAACCCAGCTC
TCTGATTTACTCCTTTTGGAAAACCCATGGAATTTCATGTATAAGGCTTTCATTTGTATTTTAAGGTTTTTCTGTTTGTTTTGAGTATATACATGGTGCTCAATAGCAACATCTTAGCAGATGAAGCAGTTTATGATTCCACTCCCTCCT
GTATGACAGGTAGCCACTATACTGAATCAAGGTGCTGAACTCAAATCACAAAATTCTGGCTTACCGATACAACAACCAATACATCTTTGTTCTGTAATGTAAAATTTGACTCCTTACTTTTATAACTTATTAAAGTTAAAATGTCTGTGT
TTTTGCAAATCATG

>AGAP1_ADAMTS2_ENST00000428334_ENST00000251582_236653483_178553131 length=4111nt
Breakpoint=76nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGGGTCCCAGTTCACCAAGTATGGCTGCCGCCGGAGGCTGGACCACAAGATGGTACACCGTGGCTTCTGTGCCGCC
CTCTCGAAGCCCAAAGCCATCCGCAGAGCGTGCAACCCACAGGAATGCTCCCAGCCAGTGTGGGTCACAGGCGAATGGGAGCCATGTAGCCAGACCTGTGGGCGGACAGGCATGCAGGTGCGCTCCGTGCGCTGCATTCAGCCGCTACAC
GACAACACCACCCGCTCCGTGCACGCCAAGCACTGCAATGACGCCCGGCCCGAGAGCCGCCGGGCCTGCAGCCGCGAGCTCTGCCCTGGTCGTTGGCGAGCCGGGCCCTGGTCCCAGTGCTCAGTAACCTGTGGCAACGGCACCCAGGAG
CGGCCAGTGCTCTGCCGCACCGCGGACGACAGCTTCGGCATCTGCCAGGAGGAGCGTCCTGAGACAGCGAGGACCTGCAGGCTTGGCCCCTGTCCCCGAAACATCTCAGATCCCTCCAAGAAGAGCTACGTAGTTCAGTGGCTGTCCCGC
CCGGACCCCGACTCGCCCATCCGGAAGATCTCGTCAAAGGGCCACTGCCAAGGCGACAAGTCAATATTCTGTAGGATGGAAGTCTTGTCCCGCTATTGCTCCATCCCAGGCTACAACAAGCTGTGCTGCAAGTCCTGTAACCTGTACAAC
AACCTCACCAACGTGGAGGGCAGGATAGAGCCACCGCCTGGGAAGCACAACGACATTGACGTGTTCATGCCTACCCTCCCAGTGCCCACTGTAGCCATGGAGGTGCGGCCATCACCAAGCACCCCCCTGGAGGTCCCTCTCAATGCCTCC
AGCACCAATGCCACAGAGGATCACCCAGAAACCAATGCCGTAGATGAACCCTACAAAATCCATGGCCTGGAAGATGAAGTCCAGCCACCCAACCTAATCCCTCGACGACCGAGCCCCTATGAAAAGACCAGAAACCAAAGAATCCAAGAG
CTCATTGATGAGATGCGGAAGAAAGAGATGCTCGGAAAGTTCTAATAAAATGGAAAGATAGCATCCCTAGCATTTTTTTCTTGCTTATAGAGATATTCCATGGGATAGCAAATCCTGTGTCATGGAGATGAAGTCAAAATTCCTGATTCC
AAAAGGTTTTGAGAAAACAAAGAGGGGGAATGACGTAAGAAAGATAGGCATGAGCATGTGGTAACTAGGTTAGCACGTGTGCTTCCCAGCCCAGGAGCGACCAAATACTGTGGTGGCGTCAGGTGTGCAGTGGAGAGGAATATAGAGGCT
GTATGGCCTCCCTCAGTGAGGGCAGGGCAAGAGGGATCACTCTGAGAGAACAAAAATAGGCCCCAAGTTGCTAAGCAGTGATTGGGAACCTTCCTTTCCTTGGCGGAGATGCATGACATTCCCTACCGATCCCCAGACACAGCCTGTGGG
ACTCTTAGGAGAAATGGTGATTTACTGAATAACTGACCCGTTGCCGAGATGAGTACAATGAAGTGGAGGTGATGAACTCAAATCGTCTTCCAGGGCCAGGCGGCTGACCGGGGTGAGCGTAGTGGCCCGCTGGGGACCATGGCCGCCCTG
ACAGCCACACCCACCTGGAGCTGACTTGGTTCTGGCTGTTGCTGCCACTGTGAAATCTGTATCTCTCTCCATCTCTGCTCTACTATCCCCGGCCTTGCCAGACAGTGTTCTTTTTCGGAAGAAGTCTAGATTTTTGCATGAAAAAAACTC
AATCTTTAAAGGTCGACTCAGAACATTTTAAGGAGGCCTCCACTTGGTCTGATGCAGTCTTGCTAATTAAGAACTAAAGGCCTTCTGACCTTCTTGGTGCTCATGCTGTACGGCATCTGAATGTCTCGACCGAGTCTGAGCCGTGCAGCT
GTCCTCCACCTGCGAAAGTAATGAGAATCCTATCACGGGACATAAGGATAGGTCTAAACAGGGTCCATGCCAAGAAAACAGTGGGGTGCTCTCCCAGGCCTCTCCCCTGTCCACTAACCCTGGCCTTGCCGGCTGCCTTCCAGGCTCTGG
GGGAAGAGCTCCTGCATTCTTCCCTGGCCACCTTGGCTCCAGGGCTCCCCAGAGAGCCTCTTCCCTCCCCAAGTACCTGAGAAAGATGAGAGAGGCACGTGCTCTGCTGGGAAGGTCCAGTGAGCGGTTCAAGGGCCTGGAATCTCCCTA
CGGCCAAGTCTAAGGGTTCTGGGATTCTGGGCTTTGTGGGCTTTGCTTGCTTGCTGGGAATGGGCTTTCCCTGTCCCGCCCTGCCCCACCTCGCCTCTGTCTCTCAGAAGCTCCAGAACCCAGCAGTGACCTGCAAAATGTGGCCTCTGA
TGGGGGCTTAGGGTGGGAGATGGGGAGAGCCTACATTGTCTTTTGCTCCTTGAAAACTTTAATAGCTCCTATTTTCCAGAGAATGGTGCTTTGTGAGCAACATGCGAGTAAGAGAGAAATAGGAGGAAGGGGGAGTAGGGGCGGATGGGA
GAAGAGTGGCTCATTTTTACCTCTCACTGCCTTGACATTTTGTGAACGTGAAGCTTAAACTTTCTGGGCTTACAAGACCCAGGGGCACGTCAGCTCCTTAGATGGGCTCAGCCTGACACATAATTCTTAAACCTTTCCTGTTTAAGAAAC
TTCTAGAGGCTGTGTACTCTCACCAATCCTCTTCGAGAATTTGTTCATGTGTATTTCCCCATTATATGGATGAGGCTCAGGATAACAGCATAGTGGCTACCTTCTACTGAGTTTTGAGGTGCTAATAAGTATGTTTGTCTGAGGCTGCAC
ATGTGGGTGGCTCTGTGTGTATGATCCAAGGGACAAAATGACGATGTAGGAACCAGCAAGAACGGAATCTGGGCTGATGCTTCAGTCTCCACCTGGGTGATGGCTAGCCTCCCGCCCTCCACCACCGCATCCCACACGTGCTGCGCACTG
TCCCCGTGTCTCCTGGAGAACCAAACTGGAGAAAACCTTTCTGAGTATCTCTCATAGTACCCCTTCCTTAAGAAGATGTGGTTTAGAGCATGTGTGCAATCCTGCCTCTGTAATTAGGAAACGGAGCCCGAGGCTTTCCATTGTTGGTTG
AACCCAGGACAGCTGGTGCTATTCACAGGCTGAAGAACTGGGCAGTTCTTACTTGGGTCTGTCCTAGGATGTGGAGGAAGTTCAGGACTAACGCTAGGCAGAGAGTATGACTCGGTTTACCCAGCCTAGGGGCCTCTGGATGGGAACACT
CCATTCCAAGATCTCAGCAGAGCAGGGCTTCCTGGCTTGAGGCTGGAAGCCTTTGGGAAGAGGCCCAGCTGGGACATTCCCTGGGCACCTGTCTTCCGCTGAAGGGAGCAAGGTGCCCTCTGGGACTGACAGCCATGACCCTCTGTGCCA
TCCTCAATCCTTGAGCCATATATCAAGAGTCCTCTAGAGCCGGATGGTCCTCAAAAGTCTGTCCAAGGAATGCCAACGTTCACCGGGCTCTGAGAAACGACGCAAATCTCTGAGCTGGGGACCACTTGGAGAACCGGCTTAGTAACAGTC
CTGATCTTCGCAAGCCAGCTTCTTCTGCATCTGAGGGGCTCCTGGCGCCCAGAGGAGGCAGACAGATGTCTTCTAGCTGAGTTTCTAACCGCATGATGAGACTCAGACCTTCCGCTGCACTAGAAAATCTGCAACAGTGTCCCTGAGTCA
CTTCTCCTTAGTGGGCAGACTCGTGTTAGATTTGTGGAACCCAGCTCTCTGATTTACTCCTTTTGGAAAACCCATGGAATTTCATGTATAAGGCTTTCATTTGTATTTTAAGGTTTTTCTGTTTGTTTTGAGTATATACATGGTGCTCAA
TAGCAACATCTTAGCAGATGAAGCAGTTTATGATTCCACTCCCTCCTGTATGACAGGTAGCCACTATACTGAATCAAGGTGCTGAACTCAAATCACAAAATTCTGGCTTACCGATACAACAACCAATACATCTTTGTTCTGTAATGTAAA
ATTTGACTCCTTACTTTTATAACTTATTAAAGTTAAAATGTCTGTGTTTTTGCAAATCATG


check button N-Truncated Transcript (5UTR-3CDS) Sequences

check button C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for AGAP1_ADAMTS2

check button In-frame Fusion Protein Sequences.

check button N-Truncated Protein (5UTR-3CDS) Sequences

check button C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for AGAP1_ADAMTS2


check button TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences
NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button TCGA All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

check button CCLE All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

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Fusion Gene Exprssed Samples for AGAP1_ADAMTS2


check buttonRNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDBPRADTCGA-HI-7168-01AAGAP1

chr2

236653483-ADAMTS2

chr5

178553131

-

check buttonDNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrandSV type


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Related Drugs for AGAP1_ADAMTS2


check button PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.
PMIDFusion Gene NameDrugStudy Title

check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status