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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:CHMP4B_CBFA2T2 (FusionGDB2 ID:HG128866TG9139)

Fusion Gene Summary for CHMP4B_CBFA2T2

Fusion gene summary

Fusion gene information	Fusion gene name: CHMP4B_CBFA2T2
	Fusion gene ID: hg128866tg9139
		Hgene	Tgene
	Gene symbol	CHMP4B	CBFA2T2
	Gene ID	128866	9139
	Gene name	charged multivesicular body protein 4B	CBFA2/RUNX1 partner transcriptional co-repressor 2
	Synonyms	C20orf178\|CHMP4A\|CTPP3\|CTRCT31\|SNF7\|SNF7-2\|Shax1\|VPS32B\|Vps32-2\|dJ553F4.4	EHT\|MTGR1\|ZMYND3\|p85
	Cytomap	20q11.22	20q11.21-q11.22
	Type of gene	protein-coding	protein-coding
	Description	charged multivesicular body protein 4bSNF7 homolog associated with Alix 1Snf7 homologue associated with Alix 1chromatin modifying protein 4Bchromatin-modifying protein 4bvacuolar protein-sorting-associated protein 32-2	protein CBFA2T2CBFA2/RUNX1 translocation partner 2ETO homolog on chromosome 20ETO homologous on chromosome 20MTG8-like proteinMTG8-related protein 1core-binding factor, runt domain, alpha subunit 2; translocated to, 2myeloid translocation gene-rela
	Modification date	20240407	20240305
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000217402,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 11 X 4 X 9=396	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 7 X 25 X 18=3150
	# samples	25	38
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(25/39610)=-0.663572335417522 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(38/315010)=-3.05128050494369 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CHMP4B [Title/Abstract] AND CBFA2T2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CHMP4B(32399464)-CBFA2T2(32224445), # samples:1

Fusion gene breakpoints across CHMP4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CBFA2T2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for CHMP4B_CBFA2T2

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
CHMP4B	chr20	32399464	CBFA2T2	chr20	32399464
CHMP4B	chr20	32399464	CBFA2T2	chr20	32232153
CHMP4B	chr20	32399464	CBFA2T2	chr20	32224446
CHMP4B	chr20	33811658	CBFA2T2	chr20	33644347
CHMP4B	chr20	33811658	CBFA2T2	chr20	33623115
CHMP4B	chr20	33811658	CBFA2T2	chr20	33636640

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for CHMP4B_CBFA2T2

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CHMP4B	GO:0001778	plasma membrane repair	24482116
Hgene	CHMP4B	GO:0039702	viral budding via host ESCRT complex	24878737
Hgene	CHMP4B	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	17984323
Hgene	CHMP4B	GO:0046761	viral budding from plasma membrane	24878737
Hgene	CHMP4B	GO:0051258	protein polymerization	18209100
Hgene	CHMP4B	GO:0071985	multivesicular body sorting pathway	16554368
Tgene	CBFA2T2	GO:0010976	positive regulation of neuron projection development	19026687
Tgene	CBFA2T2	GO:0045892	negative regulation of DNA-templated transcription	23251453

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Fusion Genomic Features for CHMP4B_CBFA2T2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32224445	+	1.25e-14	1.00e+00
CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32232152	+	6.96e-13	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for CHMP4B_CBFA2T2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000217402	ENST00000491618	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32224445	+
Frame-shift	ENST00000217402	ENST00000342704	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32232152	+
In-frame	ENST00000217402	ENST00000342704	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32224445	+
In-frame	ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32224445	+
In-frame	ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32232152	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000217402	ENST00000342704	CHMP4B	chr20	32399464	CBFA2T2	chr20	32224445	355	94
ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	CBFA2T2	chr20	32224445	355	249
ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	CBFA2T2	chr20	32232152	355	249

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000217402	ENST00000342704	CHMP4B	chr20	32399464	CBFA2T2	chr20	32224445	3.38e-03	9.97e-01
ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	CBFA2T2	chr20	32224445	1.90e-02	9.81e-01
ENST00000217402	ENST00000375279	CHMP4B	chr20	32399464	CBFA2T2	chr20	32232152	6.22e-01	3.78e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000217402	ENST00000491618	CHMP4B	chr20	32399464	CBFA2T2	chr20	32224445	0.00e+00	9.50e-03

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Fusion Protein Retained/Non-Retained Functional Features for CHMP4B_CBFA2T2

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

CHMP4B_CBFA2T2_chr20-32399464_chr20-32224445.png

CHMP4B_CBFA2T2_chr20-32399464_chr20-32232152.png

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CHMP4B

chr20:32399464

chr20:32224445

ENST00000217402

Q9H444

8_19

63.333333333333336

225.0

Compositional bias

Gly residues

Hgene

CHMP4B

chr20:32399464

chr20:32232152

ENST00000217402

Q9H444

8_19

63.333333333333336

225.0

Compositional bias

Gly residues

Hgene

CHMP4B

chr20:32399464

chr20:32224445

ENST00000217402

Q9H444

1_23

63.333333333333336

225.0

Region

Disordered

Hgene

CHMP4B

chr20:32399464

chr20:32232152

ENST00000217402

Q9H444

1_23

63.333333333333336

225.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

451_491

409.3333333333333

596.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

583_598

409.3333333333333

596.0

Compositional bias

Low complexity

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

583_598

505.0

605.0

Compositional bias

Low complexity

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

435_484

409.3333333333333

596.0

Region

Nervy homology region 3 (NHR3)

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

547_604

409.3333333333333

596.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

547_604

505.0

605.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

507_543

409.3333333333333

596.0

Zinc finger

MYND-type

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

507_543

505.0

605.0

Zinc finger

MYND-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CHMP4B

chr20:32399464

chr20:32224445

ENST00000217402

Q9H444

23_183

63.333333333333336

225.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHMP4B

chr20:32399464

chr20:32232152

ENST00000217402

Q9H444

23_183

63.333333333333336

225.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CHMP4B

chr20:32399464

chr20:32224445

ENST00000217402

Q9H444

185_224

63.333333333333336

225.0

Region

Disordered

Hgene

CHMP4B

chr20:32399464

chr20:32232152

ENST00000217402

Q9H444

185_224

63.333333333333336

225.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

451_491

505.0

605.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

236_251

409.3333333333333

596.0

Compositional bias

Basic and acidic residues

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

402_419

409.3333333333333

596.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

46_59

409.3333333333333

596.0

Compositional bias

Pro residues

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

64_79

409.3333333333333

596.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

88_105

409.3333333333333

596.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

236_251

505.0

605.0

Compositional bias

Basic and acidic residues

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

402_419

505.0

605.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

46_59

505.0

605.0

Compositional bias

Pro residues

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

64_79

505.0

605.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

88_105

505.0

605.0

Compositional bias

Polar residues

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

113_208

409.3333333333333

596.0

Domain

TAFH

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

113_208

505.0

605.0

Domain

TAFH

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

229_265

409.3333333333333

596.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

25_105

409.3333333333333

596.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

331_377

409.3333333333333

596.0

Region

Nervy homology region 2 (NHR2)

Tgene

CBFA2T2

chr20:32399464

chr20:32224445

ENST00000342704

O43439

397_427

409.3333333333333

596.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

229_265

505.0

605.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

25_105

505.0

605.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

331_377

505.0

605.0

Region

Nervy homology region 2 (NHR2)

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

397_427

505.0

605.0

Region

Disordered

Tgene

CBFA2T2

chr20:32399464

chr20:32232152

ENST00000375279

O43439

435_484

505.0

605.0

Region

Nervy homology region 3 (NHR3)

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for CHMP4B_CBFA2T2

In-frame Fusion Transcript Sequences.

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000342704_32399464_32224445 length=1810nt 
 Breakpoint=355nt
GGTGGCGCGGCCGGGCCCAGCTGCGGGGCGGAGGCGGAGGCGGAGGAGAGGCCTGCGGCGGCAGGGAGCGGCGGGACTGGGAGCGGGCGCCGGAGCCGACCCGAGCCGAGCCGAGCCGAGCCGAGCCGGAGCGGGCGGCGAAGGCCGGCG
CGGCGAGCAGCAACCATGTCGGTGTTCGGGAAGCTGTTCGGGGCTGGAGGGGGTAAGGCCGGCAAGGGCGGCCCGACCCCCCAGGAGGCCATCCAGCGGCTGCGGGACACGGAAGAGATGTTAAGCAAGAAACAGGAGTTCCTGGAGAAG
AAAATCGAGCAGGAGCTGACGGCCGCCAAGAAGCACGGCACCAAAAACAAGCGCGATTCTCAGAGAGAGTTCAACAGCAGGCCAGGTACAGGATACGTACCTGTGGAGTTTTGGAAAAAAACAGAAGAAGCTGTGAATAAGGTGAAAATT
CAGGCCATGTCAGAAGTACAGAAGGCCGTCGCTGAGGCAGAGCAGAAAGCCTTTGAAGTGATTGCAACAGAGAGAGCACGAATGGAGCAAACCATAGCGGATGTCAAGCGGCAGGCCGCAGAGGATGCTTTCCTCGTCATCAATGAGCAA
GAGGAGTCCACGGAGAACTGCTGGAACTGTGGCCGCAAAGCCAGCGAGACATGCAGTGGCTGCAATATCGCGCGATACTGTGGCTCTTTCTGCCAGCACAAGGACTGGGAGCGGCACCACCGCCTCTGTGGTCAGAACCTGCATGGCCAG
AGCCCCCACGGCCAGGGCCGGCCGCTGCTTCCTGTAGGCAGGGGCTCCTCTGCCAGGTCCGCCGACTGCAGCGTGCCCAGCCCAGCCCTCGACAAGACCTCGGCAACCACATCGCGTTCCTCAACACCTGCTTCTGTGACAGCTATCGAC
ACCAACGGACTCTGAGCCCCGGACTCTGCTTACCCTGATGGCTGCTCAGCACCACAGAGTGCTTGGGCTGAGGGACTGACTGTTGGAACCCGTGCATGTAGCTGCCGGGTCATCAGCAAGAAATGAATTGGAGGCAGGAAGAGTCCAAGC
CTGAATAATAACACCCCACAGCCTCTCTGTGCACTTGCTGTCTGCGGAGCCAGTGTGCCATTCTCTGCACATGGGCAGCCAGCCTGAGCTGCCTCCTCCATGGCTTTCCTGGTTTGTTCCTCTCTCCACTGAAGCTGACTTAGCCGGCCC
CTTTTCAGTGTAGACCACCAGCTCCCCTCCCCATCTCCTTGAGTCAGCAGACTGTCCAATGTGCTCAGCCAGGCTGGAGGCGGCAGGCGGCAGGCAGCAGGCTGTGGAGGAGGCCCCTCGGTCAGGGAGCGGCCTGCCTCACCCCTGAAT
AGCTCCTTCGGCCCCATCTCCATCCTCAGCAGATGACACTGATTGGCCTCACGGGGACTTGGGTAAGCAACAGGCGGCATTCAGGACTCTTCTCAACCCTGCTGTTCAGACTTGATAAGATCTCAGAGTCCACAGGAAAGAAGTCACTGT
TGCAATAAAAGCACCCGTAGTAGCAAAAACATAAAACAAATAAAACTTCCCCCACATCACAGATGATTTTGGACAAGATTTTCCAACCTTGCTGGCTACTTTAGTTTGGGACCTGTTTTTTTTCTCATTTGATTTTGCTTGTGCAGAAAA
TAGTTTCCAGCACATGGATTGATCTGAGAGAGAATGAGGCTCAGTTGTGGATAGTCTGTTTTCTCTGAGCATGTTGGCCAACTAGTATCGTCAAATTATTGAGTGGATCATCTCTTGGAAATGCAGAACTTCTGCCACCACTTGGCTATT
TGCACAGTCA

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445 length=6305nt 
 Breakpoint=355nt
GGTGGCGCGGCCGGGCCCAGCTGCGGGGCGGAGGCGGAGGCGGAGGAGAGGCCTGCGGCGGCAGGGAGCGGCGGGACTGGGAGCGGGCGCCGGAGCCGACCCGAGCCGAGCCGAGCCGAGCCGAGCCGGAGCGGGCGGCGAAGGCCGGCG
CGGCGAGCAGCAACCATGTCGGTGTTCGGGAAGCTGTTCGGGGCTGGAGGGGGTAAGGCCGGCAAGGGCGGCCCGACCCCCCAGGAGGCCATCCAGCGGCTGCGGGACACGGAAGAGATGTTAAGCAAGAAACAGGAGTTCCTGGAGAAG
AAAATCGAGCAGGAGCTGACGGCCGCCAAGAAGCACGGCACCAAAAACAAGCGCGATTCTCAGAGAGAGTTCAACAGCAGGCCAGGTACAGGATACGTACCTGTGGAGTTTTGGAAAAAAACAGAAGAAGCTGTGAATAAGGTGAAAATT
CAGGCCATGTCAGAAGTACAGAAGGCCGTCGCTGAGGCAGAGCAGAAAGCCTTTGAAGTGATTGCAACAGAGAGAGCACGAATGGAGCAAACCATAGCGGATGTCAAGCGGCAGGCCGCAGAGGATGCTTTCCTCGTCATCAATGAGCAA
GAGGAGTCCACGGAGAACTGCTGGAACTGTGGCCGCAAAGCCAGCGAGACATGCAGTGGCTGCAATATCGCGCGATACTGTGGCTCTTTCTGCCAGCACAAGGACTGGGAGCGGCACCACCGCCTCTGTGGTCAGAACCTGCATGGCCAG
AGCCCCCACGGCCAGGGCCGGCCGCTGCTTCCTGTAGGCAGGGGCTCCTCTGCCAGGTCCGCCGACTGCAGCGTGCCCAGCCCAGCCCTCGACAAGACCTCGGCAACCACATCGCGTTCCTCAACACCTGCTTCTGTGACAGCTATCGAC
ACCAACGGACTCTGAGCCCCGGACTCTGCTTACCCTGATGGCTGCTCAGCACCACAGAGTGCTTGGGCTGAGGGACTGACTGTTGGAACCCGTGCATGTAGCTGCCGGGTCATCAGCAAGAAATGAATTGGAGGCAGGAAGAGTCCAAGC
CTGAATAATAACACCCCACAGCCTCTCTGTGCACTTGCTGTCTGCGGAGCCAGTGTGCCATTCTCTGCACATGGGCAGCCAGCCTGAGCTGCCTCCTCCATGGCTTTCCTGGTTTGTTCCTCTCTCCACTGAAGCTGACTTAGCCGGCCC
CTTTTCAGTGTAGACCACCAGCTCCCCTCCCCATCTCCTTGAGTCAGCAGACTGTCCAATGTGCTCAGCCAGGCTGGAGGCGGCAGGCGGCAGGCAGCAGGCTGTGGAGGAGGCCCCTCGGTCAGGGAGCGGCCTGCCTCACCCCTGAAT
AGCTCCTTCGGCCCCATCTCCATCCTCAGCAGATGACACTGATTGGCCTCACGGGGACTTGGGTAAGCAACAGGCGGCATTCAGGACTCTTCTCAACCCTGCTGTTCAGACTTGATAAGATCTCAGAGTCCACAGGAAAGAAGTCACTGT
TGCAATAAAAGCACCCGTAGTAGCAAAAACATAAAACAAATAAAACTTCCCCCACATCACAGATGATTTTGGACAAGATTTTCCAACCTTGCTGGCTACTTTAGTTTGGGACCTGTTTTTTTTCTCATTTGATTTTGCTTGTGCAGAAAA
TAGTTTCCAGCACATGGATTGATCTGAGAGAGAATGAGGCTCAGTTGTGGATAGTCTGTTTTCTCTGAGCATGTTGGCCAACTAGTATCGTCAAATTATTGAGTGGATCATCTCTTGGAAATGCAGAACTTCTGCCACCACTTGGCTATT
TGCACAGTCATCTTGTTCTGTGTCCTTTTATCTCTCAGACCACACACATCTGGAACGCTGTGGGCATCTTCTGCCCATGGGCTCCATTTGGCACCTGCTGAGCCACAGTTGTCCTGCTGGATGTGCTGTGCAGGTTGGTAGGACTTGCCC
CCACTGTCAAGGCCTGGTCTCATCTGAAAAGCCCTCCTGGACCTCAAAGAATTCTTCAGACCTCATAGTTACAGGTCATTATATCTACTATGTTGATTTATCATCAGGCACACAACTTCTGTTTCCTTCTCTTGTGTTATCTGATAGCGT
CCCTCCTTGAGCTCATCAGAAAGGTTTTATGAAATGTGAACCATTTTGGGAAAAGCTGATCAATTTTTCTTCCTAGCTTCCCATTTTCAAATGGGACATCACTCATATCCCTTTCAGAATGTTAGGAACTGCCTCCCACATTCTTCCCTG
TCTTTTTGGGTTTTGTTTTTTGTTGTTGTGGTGGTTTTTTAACACAAAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCTGCCTTCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAG
TAGCTGAGATTACAGGCGCCCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGATCTCGAACTCCTGACCTCAGGTGACCTGCCTTGGCCTCCCAAAGTGCAGGGATTACAAGCGT
GAGCCACCATGCCCGGCCTGTCTTTTTGGTTTTGATGGGAGTCTGAGGACCCCGACCCCTCCTGCTCTCCATCTTTGAGCCTCTGGCATCCTCTCACACCCAGAAATCAGTTGGAGTAAGTTTAATTGGCCCTGCTCCAGCTGGCCTTTG
AAGCACAAGTTTAAATCTCCACCTTCTGTGCACTGACCAGAGTCTAAAATAAAAGTTGTCAGTACCATAAAGGAAAAGGGATCCACACAGGTAGCCTTCTCCTTGGATACAGGTACATCTTACTGTAAGAATTTCAAGTCCTGGCTGGGC
GCAGTGGCTCACTCCTGTAATCCCAGCACTTTGAGAGACCGAGGCAGGCAGATCACTTGAGGTCAGGAATTCAAGACCAACCTGGCCAACATGGTGAAACCCTGTCTCTAATAAAAAAAAAATAGAAAAATCAGCCGGGTGTGGTGGCAC
ACACCTGTAATCCTAGCTACTCAGGAGGCTGAGGCAAGAGAATCTCTTGAACCTGTGAGCCAGAGGTTGCAGTGAGCCGAGATTCCACCACTGCACTCCAGCCTGGGCAACAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAAAAGGCA
AAATTAAAGAATTTCAAGTCCCTAATTTACTCTAACCAAGCATTTTCAGTCTTACAAAGAAATCTAGTGCACGACACCTTTAAAATGCCTAGATTTCCATTGCCTAAAGTAAGGTGTGACCAGTGAAACAACAGCAGAGAATCATGTTCC
TTTGCTGTGGAACACATAAGCCCCACAGTTTTCCAGTCAGCCTAATACATGGGTATCCCCCGACCCCATCTGCCTCCTTAAGCCACAGTCCTTGGTGGGGAACTCTAAGGGGGACGGAGTCAGTACCCCGGACAGGGCCACATTTGCATG
AGACATGGCTGTCTCACAGGTCACAGAGCCATTACAACAGCTTACTAGTTTTTCATGGATTTGTTGGATTAACACCTTAAGCAGGTTTTTTATTGTTATTTTGTTTGTTTGTTTGTTTTGAGACGGGAGTTTCTCTCTTGTCTCCCAGGC
TGGAGTGCAATCGCGCAATCTCGGCTCACGGTAACCTCTGCCTCCCAGGTTCAAGCGAGTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGATTACAGGCATGCGCCACCACGCCCAACTAATTTTGTATTTTTAGTAGAGACGGGGTTTCT
CCTTGTTGGTCAGGCTGGTCTCAAACCCCGGACCTCAGGTGATCCCCCCACCTTGGCCTCCCAAAGTGCCAGGATTACAGGCATGAGCCACTGTGTCCGGTCTTGAGCAGGTTTTTAAAATCTCCAGTGGCCATAAAACTAGCCAGGGTA
GCTCATGCTTTTACTGGTTGGAATAAGGAGCCAAAACCAACAAAATAATATTTATTAGGGCTCGATGCCCATTTCTGTGGCTAAGGCTTAGGTTTGGTGTGCAGAGCCTGGCCTGCTCTTGTGGGCTGTGGTTGCTGTGACAGTTTCGTT
TTCTGAATCTTTGTAATGCTCTTCCACCCTGCTCGTGCTGCCCAGAGGCTGATCTGCAAACCTGGGCAGTATTCCACACTGAAGCTCAGTTTGCAAACCTTCTGCTGTGTTAATTCTGGTCAGTTTCACACAGAAGTCACGAGGGCCTCT
GCCCAGGACCTTCTATTCACATTTCAAGAATCCCTTTCTGAAATTCTCCAACTCTCTGGTCAGGAGGAGGAGCACCATTGGGGCGGGGTAGGCAGCTAGAGGCGCAGGAGCGAATCCAGGTTCCTTGCGTGGTTCCCAGCCTCTGCTGAC
AGCACCTCAGCTACCAGGTGGGGAGTGGAAATTCAGCCTGCTTAGAGGACTGACCTCTACAGTTCATATTTGCAGTGACATAAAAGGCAAAGAGGAGCTGGCATGGTGGTACAGAAGGTATCAGTCAAGCGCAGGCTCTTCAGAAACCTA
GAAACTAAAAAGAGATGCAACATGTGACTGGCCATCAGCCAGACATGTCTAGGGTGAGACCAGTGCTCAGCACCACCCGCCAAGGAACACTGATGAGTTGTGGGACATTATGGTCGGCCAAGTGAGGAATGATTGCAGGGACCAGAGAAG
ACCAAAGATGCCAGATGTCCCCAGAGTTTCTTGAGGGCTGGGTTTCACGTCTTTGCTTGTCCTTTTTGTCCCCACTTGCCTGCACCGTGCCTGACTCATCCAGTGGGGAAGGTGACTCAAGAAGTTGTTTAAGCCTAGGCCTAGGCAGTC
CACTTCGGGAGGTGGGGGCACTCCACACTGGGGGGCCCTGCAGCTCCAGGGCTGGTGCTCTAGCAGATCCGCTCAGGCACGGTTGGGTGACCGTGGGGTCACCGATTGCGTAGATTATTTCTAGGGCAGTGCTGGGTTAGAAATGTCTGT
CTGGAAACAGGACACATCTTGCCACCACAAGTCCACACCTGGCCTTGGCTGCTGCCCGCTCTCTGCAGCGTGGATTTCCTTTGCCCATTTGGGCCAGAAGGTCACCAGGAGTTCATCACTGCTTAGTGTCAACTTGACATCTTCAGCTTC
CAGACAGAAAACCCATGCTTTACTTTGTACAGCCCTGTCCCAGAGTTAGTAAGCCTCGGCTTGTCACCTGCTTGCAAAGGGTATAGACATCATTCTGGGTAGTTCTAGAGGATATCGCAACAAGTGCGTTTGAAGGTTCAGCACAGCTGG
AATTGTACGGTAGTGAGCTCTTCAAAATGAAAACAGAATGACCGGATGGCCATCTGTCCTGGAAACTGTAGAATTGAATAAATCACTGAAAATAGAACACTTCTTGGAGGCTTTCTTCAGAACTGAACTAGAAACAAGGTTTCCAGGCTC
CCAGGTCAGTAGACCAAACCAACTTCCTTAGATTTTTTTTTTTAAGCTGTTTGCAGAAAACTGGGTGGTAGCGTGTCTGAACCAAACGGAAGAATAGCCAGCGGAGCATGGACTGTTCCAGCACGGGCCAGATGGCCAGCTGTCGAGAGC
AGCCCTGCCCAGATTGCGGTGGGGGCTGTGCCAGCGGCTCCGCAGGGCCCTTCCAACTCTGGAGTGTCTGTAGTTCTTGTGAAACCAAAACGTTGACTACCTGCCTCTTTCCTCGGGCATCGACGTGCTCATTTCCAAAGATGATGGTGC
AGGTGACCTTTTCCATCGTGAGCTAAGAGAAGGTTAGGAGGCCTGAGGGGCGGGCCTTGTGTCCCCTCCTCCCCCTCCACAGCCCCTGAGGTGGAGCTTCCCTCACAGACCCCATCTGGTCGAGCCTACGGCTGCCCAGTGTACACTCAG
TGATGCTTATACCAAATAGGGCATGTGCGCTGGTGTCTGTTGGGGACAGCCCCATCCCTACCTTGGAGTCGGCAGAGAAGCAGCAATAAGCATTAGGCGAATGATTGAAAGGGCTGCTGCGCCAAGAGGCCTTCAGTCCCCTTAACGTGG
CTTTCCAACTTCCTGACGAGGCTACAAAGGCTCCGCTCACAAAAGAAAGCCAATAATGTAAATAAATAGAAAACGAAGCCTCCACGCGTGGTTTTTAAAGGGGGATGATGAATGTGACACCACCCACAGAATGCATTAGAATCTGGTTTT
TCTGTGCTTTGTCATTTTACTCTGATAGGAATTTTTGTTACCTAACTCTGTGCATAACTTATTTAATGTACTGTATAAATGAACCAAAACTGTTAAATATGTATTTAGTTTGTTCTACTTAAAGTAGTCAATAAAAAGGCTATATTCCTT
TTCTG

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152 length=6045nt 
 Breakpoint=355nt
GGTGGCGCGGCCGGGCCCAGCTGCGGGGCGGAGGCGGAGGCGGAGGAGAGGCCTGCGGCGGCAGGGAGCGGCGGGACTGGGAGCGGGCGCCGGAGCCGACCCGAGCCGAGCCGAGCCGAGCCGAGCCGGAGCGGGCGGCGAAGGCCGGCG
CGGCGAGCAGCAACCATGTCGGTGTTCGGGAAGCTGTTCGGGGCTGGAGGGGGTAAGGCCGGCAAGGGCGGCCCGACCCCCCAGGAGGCCATCCAGCGGCTGCGGGACACGGAAGAGATGTTAAGCAAGAAACAGGAGTTCCTGGAGAAG
AAAATCGAGCAGGAGCTGACGGCCGCCAAGAAGCACGGCACCAAAAACAAGCGCGAACTGCTGGAACTGTGGCCGCAAAGCCAGCGAGACATGCAGTGGCTGCAATATCGCGCGATACTGTGGCTCTTTCTGCCAGCACAAGGACTGGGA
GCGGCACCACCGCCTCTGTGGTCAGAACCTGCATGGCCAGAGCCCCCACGGCCAGGGCCGGCCGCTGCTTCCTGTAGGCAGGGGCTCCTCTGCCAGGTCCGCCGACTGCAGCGTGCCCAGCCCAGCCCTCGACAAGACCTCGGCAACCAC
ATCGCGTTCCTCAACACCTGCTTCTGTGACAGCTATCGACACCAACGGACTCTGAGCCCCGGACTCTGCTTACCCTGATGGCTGCTCAGCACCACAGAGTGCTTGGGCTGAGGGACTGACTGTTGGAACCCGTGCATGTAGCTGCCGGGT
CATCAGCAAGAAATGAATTGGAGGCAGGAAGAGTCCAAGCCTGAATAATAACACCCCACAGCCTCTCTGTGCACTTGCTGTCTGCGGAGCCAGTGTGCCATTCTCTGCACATGGGCAGCCAGCCTGAGCTGCCTCCTCCATGGCTTTCCT
GGTTTGTTCCTCTCTCCACTGAAGCTGACTTAGCCGGCCCCTTTTCAGTGTAGACCACCAGCTCCCCTCCCCATCTCCTTGAGTCAGCAGACTGTCCAATGTGCTCAGCCAGGCTGGAGGCGGCAGGCGGCAGGCAGCAGGCTGTGGAGG
AGGCCCCTCGGTCAGGGAGCGGCCTGCCTCACCCCTGAATAGCTCCTTCGGCCCCATCTCCATCCTCAGCAGATGACACTGATTGGCCTCACGGGGACTTGGGTAAGCAACAGGCGGCATTCAGGACTCTTCTCAACCCTGCTGTTCAGA
CTTGATAAGATCTCAGAGTCCACAGGAAAGAAGTCACTGTTGCAATAAAAGCACCCGTAGTAGCAAAAACATAAAACAAATAAAACTTCCCCCACATCACAGATGATTTTGGACAAGATTTTCCAACCTTGCTGGCTACTTTAGTTTGGG
ACCTGTTTTTTTTCTCATTTGATTTTGCTTGTGCAGAAAATAGTTTCCAGCACATGGATTGATCTGAGAGAGAATGAGGCTCAGTTGTGGATAGTCTGTTTTCTCTGAGCATGTTGGCCAACTAGTATCGTCAAATTATTGAGTGGATCA
TCTCTTGGAAATGCAGAACTTCTGCCACCACTTGGCTATTTGCACAGTCATCTTGTTCTGTGTCCTTTTATCTCTCAGACCACACACATCTGGAACGCTGTGGGCATCTTCTGCCCATGGGCTCCATTTGGCACCTGCTGAGCCACAGTT
GTCCTGCTGGATGTGCTGTGCAGGTTGGTAGGACTTGCCCCCACTGTCAAGGCCTGGTCTCATCTGAAAAGCCCTCCTGGACCTCAAAGAATTCTTCAGACCTCATAGTTACAGGTCATTATATCTACTATGTTGATTTATCATCAGGCA
CACAACTTCTGTTTCCTTCTCTTGTGTTATCTGATAGCGTCCCTCCTTGAGCTCATCAGAAAGGTTTTATGAAATGTGAACCATTTTGGGAAAAGCTGATCAATTTTTCTTCCTAGCTTCCCATTTTCAAATGGGACATCACTCATATCC
CTTTCAGAATGTTAGGAACTGCCTCCCACATTCTTCCCTGTCTTTTTGGGTTTTGTTTTTTGTTGTTGTGGTGGTTTTTTAACACAAAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCTGC
CTTCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGAGATTACAGGCGCCCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGATCTCGAACTCCTGACCTCAGGT
GACCTGCCTTGGCCTCCCAAAGTGCAGGGATTACAAGCGTGAGCCACCATGCCCGGCCTGTCTTTTTGGTTTTGATGGGAGTCTGAGGACCCCGACCCCTCCTGCTCTCCATCTTTGAGCCTCTGGCATCCTCTCACACCCAGAAATCAG
TTGGAGTAAGTTTAATTGGCCCTGCTCCAGCTGGCCTTTGAAGCACAAGTTTAAATCTCCACCTTCTGTGCACTGACCAGAGTCTAAAATAAAAGTTGTCAGTACCATAAAGGAAAAGGGATCCACACAGGTAGCCTTCTCCTTGGATAC
AGGTACATCTTACTGTAAGAATTTCAAGTCCTGGCTGGGCGCAGTGGCTCACTCCTGTAATCCCAGCACTTTGAGAGACCGAGGCAGGCAGATCACTTGAGGTCAGGAATTCAAGACCAACCTGGCCAACATGGTGAAACCCTGTCTCTA
ATAAAAAAAAAATAGAAAAATCAGCCGGGTGTGGTGGCACACACCTGTAATCCTAGCTACTCAGGAGGCTGAGGCAAGAGAATCTCTTGAACCTGTGAGCCAGAGGTTGCAGTGAGCCGAGATTCCACCACTGCACTCCAGCCTGGGCAA
CAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAAAAGGCAAAATTAAAGAATTTCAAGTCCCTAATTTACTCTAACCAAGCATTTTCAGTCTTACAAAGAAATCTAGTGCACGACACCTTTAAAATGCCTAGATTTCCATTGCCTAAAGT
AAGGTGTGACCAGTGAAACAACAGCAGAGAATCATGTTCCTTTGCTGTGGAACACATAAGCCCCACAGTTTTCCAGTCAGCCTAATACATGGGTATCCCCCGACCCCATCTGCCTCCTTAAGCCACAGTCCTTGGTGGGGAACTCTAAGG
GGGACGGAGTCAGTACCCCGGACAGGGCCACATTTGCATGAGACATGGCTGTCTCACAGGTCACAGAGCCATTACAACAGCTTACTAGTTTTTCATGGATTTGTTGGATTAACACCTTAAGCAGGTTTTTTATTGTTATTTTGTTTGTTT
GTTTGTTTTGAGACGGGAGTTTCTCTCTTGTCTCCCAGGCTGGAGTGCAATCGCGCAATCTCGGCTCACGGTAACCTCTGCCTCCCAGGTTCAAGCGAGTCTCCTGCCTCAGCCTTCTGAGTAGCTGGGATTACAGGCATGCGCCACCAC
GCCCAACTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCTTGTTGGTCAGGCTGGTCTCAAACCCCGGACCTCAGGTGATCCCCCCACCTTGGCCTCCCAAAGTGCCAGGATTACAGGCATGAGCCACTGTGTCCGGTCTTGAGCAG
GTTTTTAAAATCTCCAGTGGCCATAAAACTAGCCAGGGTAGCTCATGCTTTTACTGGTTGGAATAAGGAGCCAAAACCAACAAAATAATATTTATTAGGGCTCGATGCCCATTTCTGTGGCTAAGGCTTAGGTTTGGTGTGCAGAGCCTG
GCCTGCTCTTGTGGGCTGTGGTTGCTGTGACAGTTTCGTTTTCTGAATCTTTGTAATGCTCTTCCACCCTGCTCGTGCTGCCCAGAGGCTGATCTGCAAACCTGGGCAGTATTCCACACTGAAGCTCAGTTTGCAAACCTTCTGCTGTGT
TAATTCTGGTCAGTTTCACACAGAAGTCACGAGGGCCTCTGCCCAGGACCTTCTATTCACATTTCAAGAATCCCTTTCTGAAATTCTCCAACTCTCTGGTCAGGAGGAGGAGCACCATTGGGGCGGGGTAGGCAGCTAGAGGCGCAGGAG
CGAATCCAGGTTCCTTGCGTGGTTCCCAGCCTCTGCTGACAGCACCTCAGCTACCAGGTGGGGAGTGGAAATTCAGCCTGCTTAGAGGACTGACCTCTACAGTTCATATTTGCAGTGACATAAAAGGCAAAGAGGAGCTGGCATGGTGGT
ACAGAAGGTATCAGTCAAGCGCAGGCTCTTCAGAAACCTAGAAACTAAAAAGAGATGCAACATGTGACTGGCCATCAGCCAGACATGTCTAGGGTGAGACCAGTGCTCAGCACCACCCGCCAAGGAACACTGATGAGTTGTGGGACATTA
TGGTCGGCCAAGTGAGGAATGATTGCAGGGACCAGAGAAGACCAAAGATGCCAGATGTCCCCAGAGTTTCTTGAGGGCTGGGTTTCACGTCTTTGCTTGTCCTTTTTGTCCCCACTTGCCTGCACCGTGCCTGACTCATCCAGTGGGGAA
GGTGACTCAAGAAGTTGTTTAAGCCTAGGCCTAGGCAGTCCACTTCGGGAGGTGGGGGCACTCCACACTGGGGGGCCCTGCAGCTCCAGGGCTGGTGCTCTAGCAGATCCGCTCAGGCACGGTTGGGTGACCGTGGGGTCACCGATTGCG
TAGATTATTTCTAGGGCAGTGCTGGGTTAGAAATGTCTGTCTGGAAACAGGACACATCTTGCCACCACAAGTCCACACCTGGCCTTGGCTGCTGCCCGCTCTCTGCAGCGTGGATTTCCTTTGCCCATTTGGGCCAGAAGGTCACCAGGA
GTTCATCACTGCTTAGTGTCAACTTGACATCTTCAGCTTCCAGACAGAAAACCCATGCTTTACTTTGTACAGCCCTGTCCCAGAGTTAGTAAGCCTCGGCTTGTCACCTGCTTGCAAAGGGTATAGACATCATTCTGGGTAGTTCTAGAG
GATATCGCAACAAGTGCGTTTGAAGGTTCAGCACAGCTGGAATTGTACGGTAGTGAGCTCTTCAAAATGAAAACAGAATGACCGGATGGCCATCTGTCCTGGAAACTGTAGAATTGAATAAATCACTGAAAATAGAACACTTCTTGGAGG
CTTTCTTCAGAACTGAACTAGAAACAAGGTTTCCAGGCTCCCAGGTCAGTAGACCAAACCAACTTCCTTAGATTTTTTTTTTTAAGCTGTTTGCAGAAAACTGGGTGGTAGCGTGTCTGAACCAAACGGAAGAATAGCCAGCGGAGCATG
GACTGTTCCAGCACGGGCCAGATGGCCAGCTGTCGAGAGCAGCCCTGCCCAGATTGCGGTGGGGGCTGTGCCAGCGGCTCCGCAGGGCCCTTCCAACTCTGGAGTGTCTGTAGTTCTTGTGAAACCAAAACGTTGACTACCTGCCTCTTT
CCTCGGGCATCGACGTGCTCATTTCCAAAGATGATGGTGCAGGTGACCTTTTCCATCGTGAGCTAAGAGAAGGTTAGGAGGCCTGAGGGGCGGGCCTTGTGTCCCCTCCTCCCCCTCCACAGCCCCTGAGGTGGAGCTTCCCTCACAGAC
CCCATCTGGTCGAGCCTACGGCTGCCCAGTGTACACTCAGTGATGCTTATACCAAATAGGGCATGTGCGCTGGTGTCTGTTGGGGACAGCCCCATCCCTACCTTGGAGTCGGCAGAGAAGCAGCAATAAGCATTAGGCGAATGATTGAAA
GGGCTGCTGCGCCAAGAGGCCTTCAGTCCCCTTAACGTGGCTTTCCAACTTCCTGACGAGGCTACAAAGGCTCCGCTCACAAAAGAAAGCCAATAATGTAAATAAATAGAAAACGAAGCCTCCACGCGTGGTTTTTAAAGGGGGATGATG
AATGTGACACCACCCACAGAATGCATTAGAATCTGGTTTTTCTGTGCTTTGTCATTTTACTCTGATAGGAATTTTTGTTACCTAACTCTGTGCATAACTTATTTAATGTACTGTATAAATGAACCAAAACTGTTAAATATGTATTTAGTT
TGTTCTACTTAAAGTAGTCAATAAAAAGGCTATATTCCTTTTCTG

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000491618_32399464_32224445 length=355nt 
 Breakpoint=355nt
GGTGGCGCGGCCGGGCCCAGCTGCGGGGCGGAGGCGGAGGCGGAGGAGAGGCCTGCGGCGGCAGGGAGCGGCGGGACTGGGAGCGGGCGCCGGAGCCGACCCGAGCCGAGCCGAGCCGAGCCGAGCCGGAGCGGGCGGCGAAGGCCGGCG
CGGCGAGCAGCAACCATGTCGGTGTTCGGGAAGCTGTTCGGGGCTGGAGGGGGTAAGGCCGGCAAGGGCGGCCCGACCCCCCAGGAGGCCATCCAGCGGCTGCGGGACACGGAAGAGATGTTAAGCAAGAAACAGGAGTTCCTGGAGAAG
AAAATCGAGCAGGAGCTGACGGCCGCCAAGAAGCACGGCACCAAAAACAAGCGCG

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Fusion Protein Sequence for CHMP4B_CBFA2T2

In-frame Fusion Protein Sequences.

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000342704_32399464_32224445 length=94nt
MERPRRSRPKNWDRVPYRRDCGASACRTSPPSGETAPLLPRAPHHRGLGGPAANTASLRCPGVLLRALAAQAPPRILRSRFRKKSTSSSATETT

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445 length=249nt
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152 length=249nt
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for CHMP4B_CBFA2T2

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.A461T_249_A106T length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVTEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.R487Q;p.A524T_249_R132Q;A169T length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKQQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNITRYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.A483V_249_A128V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIVDVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.G563S_249_G208S length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVSRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.A524V_249_A169V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIVRYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.T592A_249_T237A length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSAPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.V575M_249_V220M length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSMPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.A452V_249_A97V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQVMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.K447N_249_K92N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNNVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.E462K_249_E107K length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAKAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.V575M_249_V220M length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSMPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.S420Y_249_S65Y length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDYQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_5-gene_p.S2L_249_S2L length=249AA
MLVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.E462K_249_E107K length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAKAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.G528S_249_G173S length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCSSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_5-gene_p.P20Q_249_P20Q length=249AA
MSVFGKLFGAGGGKAGKGGQTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.G565D_249_G210D length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRDSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.R538W_249_R183W length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWEWHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.D484N_249_D129N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIANVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.F530L_249_F175L length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSLCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_5-gene_p.G5W_249_G5W length=249AA
MSVFWKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.F424L_249_F69L length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQRELNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_5-gene_p.E34D_249_E34D length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEDMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.A594V_249_A239V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPVSVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.P561R_249_P206R length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLRVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.D419N_249_D64N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRNSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.N522I_249_N167I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCIIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_3-gene_p.F437I_249_F82I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEIWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32224445_5-gene_p.F42I_249_F42I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEILEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.A461T_249_A106T length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVTEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.R487Q;p.A524T_249_R132Q;A169T length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKQQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNITRYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.A483V_249_A128V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIVDVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.G563S_249_G208S length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVSRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.A524V_249_A169V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIVRYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.T592A_249_T237A length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSAPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.V575M_249_V220M length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSMPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.A452V_249_A97V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQVMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.K447N_249_K92N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNNVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.E462K_249_E107K length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAKAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.V575M_249_V220M length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSMPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.S420Y_249_S65Y length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDYQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_5-gene_p.S2L_249_S2L length=249AA
MLVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.E462K_249_E107K length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAKAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.G528S_249_G173S length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCSSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_5-gene_p.P20Q_249_P20Q length=249AA
MSVFGKLFGAGGGKAGKGGQTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.G565D_249_G210D length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRDSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.R538W_249_R183W length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWEWHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.D484N_249_D129N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIANVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.F530L_249_F175L length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSLCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_5-gene_p.G5W_249_G5W length=249AA
MSVFWKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.F424L_249_F69L length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQRELNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_5-gene_p.E34D_249_E34D length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEDMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.A594V_249_A239V length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPVSVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.P561R_249_P206R length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLRVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.D419N_249_D64N length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRNSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.N522I_249_N167I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCIIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_3-gene_p.F437I_249_F82I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEFLEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEIWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

>CHMP4B_CBFA2T2_ENST00000217402_ENST00000375279_32399464_32232152_5-gene_p.F42I_249_F42I length=249AA
MSVFGKLFGAGGGKAGKGGPTPQEAIQRLRDTEEMLSKKQEILEKKIEQELTAAKKHGTKNKRDSQREFNSRPGTGYVPVEFWKKTEEAVNKVKIQAMSEVQKAVAEAEQKAFEVIATERARMEQTIADVKRQAAEDAFLVINEQEESTE
NCWNCGRKASETCSGCNIARYCGSFCQHKDWERHHRLCGQNLHGQSPHGQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNGL

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-20-1686-01A	3-gene	p.A461T	249	A106T
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-2W-A8YY-01A	3-gene	p.R487Q;p.A524T	249	R132Q;A169T
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-A5-A0G2-01A	3-gene	p.A483V	249	A128V
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-A6-6648-01A	3-gene	p.G563S	249	G208S
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-AA-3864-01A	3-gene	p.A524V	249	A169V
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-AN-A046-01A	3-gene	p.T592A	249	T237A
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-AU-6004-01A	3-gene	p.V575M	249	V220M
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-AZ-4315-01A	3-gene	p.A452V	249	A97V
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-BF-A1Q0-01A	3-gene	p.K447N	249	K92N
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-BH-A2L8-01A	3-gene	p.E462K	249	E107K
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-BR-7703-01A	3-gene	p.V575M	249	V220M
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-BS-A0UV-01A	3-gene	p.S420Y	249	S65Y
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-C5-A902-01A	5-gene	p.S2L	249	S2L
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-C8-A274-01A	3-gene	p.E462K	249	E107K
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-CJ-4923-01A	3-gene	p.G528S	249	G173S
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-D3-A3CE-06A	5-gene	p.P20Q	249	P20Q
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-D3-A8GN-06A	3-gene	p.G565D	249	G210D
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-DU-6392-01A	3-gene	p.R538W	249	R183W
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-DU-6407-02B	3-gene	p.D484N	249	D129N
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-E7-A5KE-01A	3-gene	p.F530L	249	F175L
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-EB-A299-01A	5-gene	p.G5W	249	G5W
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-EE-A181-06A	3-gene	p.F424L	249	F69L
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-EO-A3B0-01A	5-gene	p.E34D	249	E34D
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-FW-A3R5-06A	3-gene	p.A594V	249	A239V
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-IB-7651-01A	3-gene	p.P561R	249	P206R
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-JW-A5VL-01A	3-gene	p.D419N	249	D64N
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-OE-A75W-01A	3-gene	p.N522I	249	N167I
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-RD-A8N6-01A	3-gene	p.F437I	249	F82I
ENST00000217402_ENST00000375279_32399464_32224445	TCGA-WP-A9GB-01A	5-gene	p.F42I	249	F42I
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-20-1686-01A	3-gene	p.A461T	249	A106T
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-2W-A8YY-01A	3-gene	p.R487Q;p.A524T	249	R132Q;A169T
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-A5-A0G2-01A	3-gene	p.A483V	249	A128V
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-A6-6648-01A	3-gene	p.G563S	249	G208S
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-AA-3864-01A	3-gene	p.A524V	249	A169V
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-AN-A046-01A	3-gene	p.T592A	249	T237A
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-AU-6004-01A	3-gene	p.V575M	249	V220M
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-AZ-4315-01A	3-gene	p.A452V	249	A97V
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-BF-A1Q0-01A	3-gene	p.K447N	249	K92N
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-BH-A2L8-01A	3-gene	p.E462K	249	E107K
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-BR-7703-01A	3-gene	p.V575M	249	V220M
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-BS-A0UV-01A	3-gene	p.S420Y	249	S65Y
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-C5-A902-01A	5-gene	p.S2L	249	S2L
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-C8-A274-01A	3-gene	p.E462K	249	E107K
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-CJ-4923-01A	3-gene	p.G528S	249	G173S
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-D3-A3CE-06A	5-gene	p.P20Q	249	P20Q
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-D3-A8GN-06A	3-gene	p.G565D	249	G210D
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-DU-6392-01A	3-gene	p.R538W	249	R183W
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-DU-6407-02B	3-gene	p.D484N	249	D129N
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-E7-A5KE-01A	3-gene	p.F530L	249	F175L
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-EB-A299-01A	5-gene	p.G5W	249	G5W
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-EE-A181-06A	3-gene	p.F424L	249	F69L
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-EO-A3B0-01A	5-gene	p.E34D	249	E34D
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-FW-A3R5-06A	3-gene	p.A594V	249	A239V
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-IB-7651-01A	3-gene	p.P561R	249	P206R
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-JW-A5VL-01A	3-gene	p.D419N	249	D64N
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-OE-A75W-01A	3-gene	p.N522I	249	N167I
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-RD-A8N6-01A	3-gene	p.F437I	249	F82I
ENST00000217402_ENST00000375279_32399464_32232152	TCGA-WP-A9GB-01A	5-gene	p.F42I	249	F42I

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for CHMP4B_CBFA2T2

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		BRCA	TCGA-AR-A256-01A	CHMP4B	chr20	32399464	-	CBFA2T2	chr20	0	+
ChimerDB		BRCA	TCGA-AR-A256-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
ChimerDB		BRCA	TCGA-AR-A256	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
ChimerDB		BRCA	TCGA-B6-A0I1-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
ChimerDB		LIHC	TCGA-FV-A496-01A	CHMP4B	chr20	32399464	-	CBFA2T2	chr20	0	+
ChimerDB		LIHC	TCGA-FV-A496-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
ChimerDB		STAD	TCGA-CG-4449-01A	CHMP4B	chr20	32399464	-	CBFA2T2	chr20	0	+
ChimerDB		STAD	TCGA-CG-4449-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
ChimerDB		STAD	TCGA-CG-4449	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32399464	+
TCGAfusionPortal		BRCA	TCGA-AR-A256-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32232153	+
WashU		BRCA	TCGA-AR-A256-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32232153	+
WashU		LIHC	TCGA-FV-A496-01A	CHMP4B	chr20	32399464	+	CBFA2T2	chr20	32224446	+
cBioPortal	BRCA_TCGA_PAN_CAN_ATLAS_2018	BRCA	TCGA-AR-A256-01	CHMP4B	chr20	33811658		CBFA2T2	chr20	33644347
cBioPortal	BRCA_TCGA_PAN_CAN_ATLAS_2018	BRCA	TCGA-B6-A0I1-01	CHMP4B	chr20	33811658		CBFA2T2	chr20	33623115
cBioPortal	LIHC_TCGA_PAN_CAN_ATLAS_2018	HCC	TCGA-FV-A496-01	CHMP4B	chr20	33811658		CBFA2T2	chr20	33636640

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for CHMP4B_CBFA2T2

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status