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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:C4orf32_EIF4E (FusionGDB2 ID:HG132720TG1977)

Fusion Gene Summary for C4orf32_EIF4E

Fusion gene summary

Fusion gene information	Fusion gene name: C4orf32_EIF4E
	Fusion gene ID: hg132720tg1977
		Hgene	Tgene
	Gene symbol	C4orf32	EIF4E
	Gene ID	132720	1977
	Gene name	family with sequence similarity 241 member A	eukaryotic translation initiation factor 4E
	Synonyms	C4orf32	AUTS19\|CBP\|EIF4E1\|EIF4EL1\|EIF4F\|eIF-4E
	Cytomap	4q25	4q23
	Type of gene	protein-coding	protein-coding
	Description	uncharacterized protein FAM241Auncharacterized protein C4orf32	eukaryotic translation initiation factor 4EeIF-4F 25 kDa subuniteukaryotic translation initiation factor 4E-like 1mRNA cap-binding protein
	Modification date	20240305	20240411
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000309733,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 2 X 4=32	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 3 X 6 X 7=126
	# samples	5	16
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(5/3210)=0.643856189774725 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(16/12610)=0.344648171387446 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: C4orf32 [Title/Abstract] AND EIF4E [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	C4orf32(113066889)-EIF4E(99823133), # samples:1

Fusion gene breakpoints across C4orf32 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EIF4E (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for C4orf32_EIF4E

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
C4orf32	chr4	113066889	EIF4E	chr4	99823133

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for C4orf32_EIF4E

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
C4orf32-EIF4E	Promoter / Enhancer Hijacking M6		Promoter swap drives high eIF4E cap-binding protein expression, hyperactivating translation initiation of c-Myc, VEGF, and Cyclin D1.		eIF4E/eIF4F inhibitors (ribavirin, eFT508); MNK1/2 kinase inhibitors		Hyperproliferative solid tumors and lymphomas

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
C4orf32-EIF4E	Promoter / Enhancer Hijacking M6	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 37601696; Title: Biological functions and research progress of eIF4E.	Promoter swap drives high eIF4E cap-binding protein expression, hyperactivating translation initiation of c-Myc, VEGF, and Cyclin D1.	Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 37601696; Title: Biological functions and research progress of eIF4E.	eIF4E/eIF4F inhibitors (ribavirin, eFT508); MNK1/2 kinase inhibitors	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 37601696; Title: Biological functions and research progress of eIF4E.; PMID: 40702697; Title: Discovery of a Novel MNK Inhibitor (NSP-1047) with In Vivo Anti-acute Myeloid Leukemia Activity.	Hyperproliferative solid tumors and lymphomas	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 37601696; Title: Biological functions and research progress of eIF4E.; PMID: 39652777; Title: The GATA-3-dependent transcriptome and tumor microenvironment are regulated by eIF4E and XPO1 in T-cell lymphomas.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	EIF4E	GO:0006417	regulation of translation	22578813

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Fusion Genomic Features for C4orf32_EIF4E

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-	5.67e-06	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for C4orf32_EIF4E

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000309733	ENST00000504472	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-
In-frame	ENST00000309733	ENST00000280892	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-
In-frame	ENST00000309733	ENST00000450253	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-
In-frame	ENST00000309733	ENST00000504432	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-
In-frame	ENST00000309733	ENST00000505992	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000309733	ENST00000280892	C4orf32	chr4	113066889	EIF4E	chr4	99823133	337	300
ENST00000309733	ENST00000450253	C4orf32	chr4	113066889	EIF4E	chr4	99823133	337	417
ENST00000309733	ENST00000504432	C4orf32	chr4	113066889	EIF4E	chr4	99823133	337	300
ENST00000309733	ENST00000505992	C4orf32	chr4	113066889	EIF4E	chr4	99823133	337	300

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000309733	ENST00000280892	C4orf32	chr4	113066889	EIF4E	chr4	99823133	2.11e-03	9.98e-01
ENST00000309733	ENST00000450253	C4orf32	chr4	113066889	EIF4E	chr4	99823133	1.15e-02	9.88e-01
ENST00000309733	ENST00000504432	C4orf32	chr4	113066889	EIF4E	chr4	99823133	2.09e-03	9.98e-01
ENST00000309733	ENST00000505992	C4orf32	chr4	113066889	EIF4E	chr4	99823133	2.06e-03	9.98e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for C4orf32_EIF4E

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

C4orf32_EIF4E_chr4-113066889_chr4-99823133.png

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

EIF4E

chr4:113066889

chr4:99823133

ENST00000280892

P06730

132_139

26.0

238.0

Region

EIF4EBP1/2/3 binding

Tgene

EIF4E

chr4:113066889

chr4:99823133

ENST00000280892

P06730

37_40

26.0

238.0

Region

EIF4EBP1/2/3 binding

Tgene

EIF4E

chr4:113066889

chr4:99823133

ENST00000280892

P06730

73_77

26.0

238.0

Region

EIF4EBP1/2/3 binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

C4orf32

chr4:113066889

chr4:99823133

ENST00000309733

Q8N8J7

1_68

51.0

133.0

Region

Disordered

Hgene

C4orf32

chr4:113066889

chr4:99823133

ENST00000309733

Q8N8J7

100_120

51.0

133.0

Transmembrane

Helical

Tgene

EIF4E

chr4:113066889

chr4:99823133

ENST00000280892

P06730

1_30

26.0

238.0

Region

Disordered

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for C4orf32_EIF4E

In-frame Fusion Transcript Sequences.

>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133 length=1236nt 
 Breakpoint=337nt
GAGCCAGTGACAGGAGGGGCCGGGCTGGTACTTCAGGCGCCCAGGCCGGCGGGGCGCGCTCCGGCGGCTCCTGTCAGCGGCGGGTGCGGCGGATCCCAGGGCAGCCTTCGGGCGGCGGCGCTGCCTGGTGCGTCGCGGCGTGGTCCTCCG
GCGGCTGTCCGGGGCGGTAGGAGTTGGCTGCGGGATGTGCTCAGCCGGGGAGCTGCTGCGGGGCGGCGACGGCGGGGAACGCGACGAGGACGGGGACGCGCTGGCGGAGCGGGAGGCGGCAGGGACCGGGTGGGATCCCGGGGCGAGCCC
GCGGCGGCGCGGACAGCGGCCGAAGGAGAGCGAGCAGGAAACCACCCCTACTCCTAATCCCCCGACTACAGAAGAGGAGAAAACGGAATCTAATCAGGAGGTTGCTAACCCAGAACACTATATTAAACATCCCCTACAGAACAGATGGGC
ACTCTGGTTTTTTAAAAATGATAAAAGCAAAACTTGGCAAGCAAACCTGCGGCTGATCTCCAAGTTTGATACTGTTGAAGACTTTTGGGCTCTGTACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTACTCACTTTT
TAAGGATGGTATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGGGGAGGACGATGGCTAATTACATTGAACAAACAGCAGAGACGAAGTGACCTCGATCGCTTTTGGCTAGAGACACTTCTGTGCCTTATTGGAGAATCTTTTGATGA
CTACAGTGATGATGTATGTGGCGCTGTTGTTAATGTTAGAGCTAAAGGTGATAAGATAGCAATATGGACTACTGAATGTGAAAACAGAGAAGCTGTTACACATATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCAAAGATAGT
GATTGGTTATCAGTCCCACGCAGACACAGCTACTAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAGAAGACACCTTCTGAGTATTCTCATAGGAGACTGCGTCAAGCAATCGAGATTTGGGAGCTGAACCAAAGCCTCTTCA
AAAAGCAGAGTGGACTGCATTTAAATTTGATTTCCATCTTAATGTTACTCAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTTTTTTTTTTTTTTTTGGCTAGAGTTTCCACTATCCCAATCAAAGAATTAC
AGTACACATCCCCAGAATCCATAAATGTGTTCCTGG

>C4orf32_EIF4E_ENST00000309733_ENST00000450253_113066889_99823133 length=10317nt 
 Breakpoint=337nt
GAGCCAGTGACAGGAGGGGCCGGGCTGGTACTTCAGGCGCCCAGGCCGGCGGGGCGCGCTCCGGCGGCTCCTGTCAGCGGCGGGTGCGGCGGATCCCAGGGCAGCCTTCGGGCGGCGGCGCTGCCTGGTGCGTCGCGGCGTGGTCCTCCG
GCGGCTGTCCGGGGCGGTAGGAGTTGGCTGCGGGATGTGCTCAGCCGGGGAGCTGCTGCGGGGCGGCGACGGCGGGGAACGCGACGAGGACGGGGACGCGCTGGCGGAGCGGGAGGCGGCAGGGACCGGGTGGGATCCCGGGGCGAGCCC
GCGGCGGCGCGGACAGCGGCCGAAGGAGAGCGAGCAGGAAACCACCCCTACTCCTAATCCCCCGACTACAGAAGAGGAGAAAACGGAATCTAATCAGGAGGTTGCTAACCCAGAACACTATATTAAACATCCCCTACAGAACAGATGGGC
ACTCTGGTTTTTTAAAAATGATAAAAGCAAAACTTGGCAAGCAAACCTGCGGCTGATCTCCAAGTTTGATACTGTTGAAGACTTTTGGGCTCTGTACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTACTCACTTTT
TAAGGATGGTATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGGGGAGGACGATGGCTAATTACATTGAACAAACAGCAGAGACGAAGTGACCTCGATCGCTTTTGGCTAGAGACACTTCTGTGCCTTATTGGAGAATCTTTTGATGA
CTACAGTGATGATGTATGTGGCGCTGTTGTTAATGTTAGAGCTAAAGGTGATAAGATAGCAATATGGACTACTGAATGTGAAAACAGAGAAGCTGTTACACATATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCAAAGATAGT
GATTGGTTATCAGTCCCACGCAGACACAGCTACTAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAGAAGACACCTTCTGAGTATTCTCATAGGAGACTGCGTCAAGCAATCGAGATTTGGGAGCTGAACCAAAGCCTCTTCA
AAAAGCAGAGTGGACTGCATTTAAATTTGATTTCCATCTTAATGTTACTCAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTTTTTTTTTTTTTTTTGGCTAGAGTTTCCACTATCCCAATCAAAGAATTAC
AGTACACATCCCCAGAATCCATAAATGTGTTCCTGGCCCACTCTGTAATAGTTCAGTAGAATTACCATTAATTACATACAGATTTTACCTATCCACAATAGTCAGAAAACAACTTGGCATTTCTATACTTTACAGGAAAAAAAATTCTGT
TGTTCCATTTTATGCAGAAGCATATTTTGCTGGTTTGAAAGATTATGATGCATACAGTTTTCTAGCAATTTTCTTTGTTTCTTTTTACAGCATTGTCTTTGCTGTACTCTTGCTGATGGCTGCTAGATTTTAATTTATTTGTTTCCCTAC
TTGATAATATTAGTGATTCTGATTTCAGTTTTTCATTTGTTTTGCTTTTGTTTTTTTCCTCATGTAACATTGGTGAAGGATCCAGGAATATGACACAAAGGTGGAATAAACATTAATTTTGTGCATTCTTTGGTAATTTTTTTTGTTTTT
TGTAACTACAAAGCTTTGCTACAAATTTATGCATTTCATTCAAATCAGTGATCTATGTTTGTGTGATTTCCTAAACATAATTGTGGATTATAAAAAATGTAACATCATAATTACATTCCTAACTAGAATTAGTATGTCTGTTTTTGTATC
TTTATGCTGTATTTTAACACTTTGTATTACTTAGGTTATTTTGCTTTGGTTAAAAATGGCTCAAGTAGAAAAGCAGTCCCATTCATATTAAGACAGTGTACAAAACTGTAAATAAAATGTGTACAGTGAATTGTCTTTTAGACAACTAGA
TTTGTCCTTTTATTTCTCCATCTTTATAGAAGGAATTTGTACTTCTTATTGCAAGGCAGTCTCTATATTATGTCTTCTTTTGTGGTGTCTTCCATGTGAACAGCATAAGTTTGGAGCACTAGTTTGATTATTATGTTTATTACAATTTTT
AATAAATTGAATAGGTAGTATCATATATATGGAATTAAATTGATGTGGCTATCTTTGTTTTTTTATAAAGTAAGGCACAGTCATTCAGTCTTAGGTAAATAATGTACTCTCTTAATATGTTAATACTCATGAGAATTGGGATCTGATGCA
TCACCATTTGATTGGTAGCAACAGTGGTTGTAAAACTTGGTTGCTGAATTGAGTTGTTTCTATGTTAAGTGTCAAAATGATAGTGTAGGGAAAGTACAGGTGGTGGGGACATATGCATTAAGAATCTTGTTAGTGTTGCAATCTAAATAG
AATGGAATAAACAGGTGTTAAGACATATTTATAGTGGTAAATTGTTGTAGTATGGTATTCTGTAAACTTGAAAACTTGATCTACTCTTTGTAGGTATCATTTGAAAGCAAACTTGAAAATGTTTTGTACATAGTACATACTTGTATAGTC
CTGTGAGATGAAGTATGGCTATCAGACCAAAGGATAAGCCAAACTGTAGGTAGCAGAATGGAAATTATTATTTTGAGAGGAAAATTTGTCTTTGAATGGTGATTATGACTTAATCATTTTAAAACTGATAAACTTGACAAAAACCCTGTA
TGAAATAAACATGAAATTAATAGCACTGATTTCATTGTAAAATTTTAAAGCAGTTTAAAGGGTACCACAGGTTATCACAGTACTCTCAATGCCACAAACACCTCTTGTTCAGTATTCTAGAAATACTGAATCAGAATTCTGTGTTTATTA
TAATCTCAGCATACTGTACATAATATCTGCTAGTTAAACTTGGGTAATTGGTTAAGGTGACTTACTGTCTATGTCAATATGTATAGTTTTGAGTACTTCAAGAGTTTACTTAAAAGTGATGATGTTACTGGTATGTTGGCAGTGGGTGGG
ACTGAAGTAGTGTATCTATTATAAATTGATCTATTTTCTTAATTCTAAGATGAAGTCCAATTTTAAGCATCAGCTTTTAGGTGCAAAGGAGGAATTAACACATTAAATGTATACAGTTCTAAATTTTTGAAATAACTGATGTGTAGCATT
TGATTATTGGTATTACCATTTTAGAATCATGATGTTATTTTAAACCTTTTTCCTGGGGACAAGAAAGGATAATAAATTACGCTGAATCACTTTTGGCAGTTGCCACTTAAATAGTACAGTGACTTGCAACTTTTATAACTTTATCAGCAT
CTTCTCTAAATACAAAATTAGGCTATATGTTATTTTCCAACTTACTGTTTTCTCTCTGTTTAGCAGGATATTATAAATAGATTAAATAGATATATTTTCTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTTTGTCTCCCAGGCTGG
AGTGCAGTGGCGTGATCTCCCAGTAGCTGGGACTACAAGCACCTGCCACCATGCCCGGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTTAGCCAAGATGGTCTCAATCTCCTGACTTTGTGATCTGCCTGCTTCTG
CCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGTACCCAGCCCAAATAGATGTATTTTCATAATAGAGAATTGAAATAGGCTTTAATGGGTGAATAGCAGTTTATTGTAGGCATGTGACATTTCATTTAATGAATTTAAAGTTTAT
TATCCCAATTCTACAGAAGGATTTAATGCATACTATGCAATTAAATAATTATAACACTACATAGTAATAATTTATGTGCCAGGCAGTAGTTCAGTCACTTTACATGCTTATTAACCTGCAGAATAATCTTTTGAGATGTAGGTGCTGTTA
CTGAGAATTTAACTTTTGCTTGTAAATTGCAAAGGGTGGATTTGAATTCTGGAAATTTGGTTCCAGAGACAATAATTACATAACACTTTCTCCATAGGGTACAGCCTGTCTAATAGGCTATAGTAAATCACCTCAGCTTGTTATAGGTCG
GGCATGCAAACATTTCTCCATTTTACTCCCTTTGGTAATGAATCTAGTAATAGATGGAAATTTTCCCTAGATTCACTGTGTTAGTCAGTTGGGGAAGTTTGGAGGCAAAGATACAGGAGTTTATGGGGAGGTAGTGTACATAAATATAAT
CATATGCTATATAAGGAAGTTTTGGTCAGCAGCAGACCATATATAGGATGGTGGGCCAGTAACATTGTAACACTGTATTTTTACTGTATCTTTTCCATGTTTTGTTATGTTTAGATACACAAATAACATTATGGAGTATTCAGTATGGTA
ACATGCCATACAGGTTTGTAGCCTAGGAGCAGTAATAGACTGTTCCCTGAAACCTATATTTGTGGTAGGTTTATACCATTCAGGTTTGTGTAAGTACACAACGAAATCATCTAATGGCCCATTTCTCAAAACATATTCCCATCATTAATC
AATGCATGGTCATGTTTTCGTATACATTTTAAGCTTCTGTATTCTAATCTAATATAAATGGCAAAATATTCAAACTGATAGGCATTGAGATTCTTAAATGCTAAAGTTGCATTCAAAAGGATAATTTTAGGCGTTGTGACAAAGCAGTGT
TATATTTTAAAGTTAGTGACAAGGCTATGCACCTTTTATCTCTAATTGTTTCTTACAGAATGTTTTTATTATTGAGTAGTAAAACAATAAATGTCAGATCCTTTATACAAATTCAAGATTGACATTGATAAACAAAACTTCAGCATATCA
CTCAAGGTCAGCGTAGAAATTGTGTGTCTGGAAACTTCTATAGTAATTTTATATTACTGTGACATTAGTATGTGATCACTTTTCTAGTAATGTTTTAAAAAAATATATCTTACAGGCCAGGCATAGTGCTTTATGCCTGTAATCCCAGCA
CTTTGGGAGGCCAAGGTGGCAGGATTGCATGAGTCCAGGAGTTCAACACCAGTCTGGGCAATAAAGTGAGACCCCATCGCTACAAACAAATTAAAAAATATTTATGTATGTGTGTAATATATATAATATATAACAAAACACATATGTATG
TGTATATATAGTATGTCTGGCAGAGTACAATTTAGGGGTTAAGACTGGTCCCTCACATATGGTGTGAGAAACACTGTTCACAGGTTGCTTTCCCCATTAGCCCAGGGCAACTCATTTGCCCATCATTTCCTAGAACAACCGGGTCTGTTA
CGTCTACAGTTTTCATCTTCATGCAGTTATGGATTTGGTGTCAAAAACTTTGGTCCTGTTCTCTACCATCTTAAAATAAACTCTTGTGTCCTGCTTTACTATGAATTGCAAAGTAGGCATTAGGTAGCCTTCCTACTACCATAGTTTAGA
GTTCAATATTCTTATGACCATTCTACTGGTAGAAGCAAAAAATGAACTTGTAGGCATGTGATCACATGTGCCTATGGTGCTGTCTTTTCCAGTACAGGGGAACTAATTTTCATATTTTAATCTTGCAGCTTTTTGTTTACTTCATGCATT
GTGATTTCTCATAGTTTTGCACAGAACTCACTTCCCTACCTTTTCTGAAACAAAAGTATGTATACACACATACATATGTATTGAGCACCTCTATTTACTGTGTTCCACGTGCTGGGCATATAGCAAGAACAGAATGGTCTGGGGCCCTGC
TCTAAAGAAGATTTAAAAGCAAACATATATTAAAAATGCGTGAGTCTGGCCAGGAGCAGTGGCTCATGCCTGCAACCCCAGCACTTTGGGAGGCTGAAGCGGGTGAATCACCTGAGATCAGGAGTTGAGACCAGCCTGGCCAACATGGTG
AAACCCCGTCTCTACTAAAAATACAAAAATTAGCCTGGCATGGTGGCATGCGCCTGTAATTCCAGCTACTTTGGAGACTGAGACAGGAGAATCACTTGAGCCCAGGAAGTGGAGGTTGCAGTGAGCTGAGATCGCGCCACTGCACTCCAG
CCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAACGTGTCTGTTCATAAGGTTCTACAAATAGCTGTTGTTACAGAAAATAGGACTAGGGTTTTATTACTGGGGATTATGCAGTCGAGGTAAATATAAAATGAGGTTGTT
TCTTCTTTTTTTTATTTGAGACAGAGTCTTGTTTGCCAGGCTGGAGTGCAGTGGCGTGCTCTTAGCTCCGCCTCCCGGGATCAAACGATTCTCTTGCCTCAGCCTCTCGAGTAGCTGGGACTACAGGCGCGTGCCACCACACCCAGCTGA
TTTTTGTATTTTTAGTAGAGATGGGATTTCACCATGATGGCCAGGATGGTCTCGATCTTTTGACCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCACCCGGCCCTGGTTCTAAATACTCTTC
CAGCTCTAAAACATTGATTCTAAACAGATCACATTCCAGGAGGACTCTAGCAAACCAGCATATGCAAATTATAGCTTTTGCAAGACCGTTTCTACTTTTATATTACTGAACTCTATATGATTGTCCAAGTAAAGTTTTGTGTCTCTTTGA
TTATTTGATTGTACTTTAAAATTTTTTCACCATTCATTTAACATTTTTTACCATACTGTAGTATTTTTAATGCAATTGTGTTTGCATTGGTGTGGCTTTAGAGGCTTCTCCAACCACCTTCCCAAAATACTGATCTGTGATTTTTTTCTT
TAATGTTTGGCCAAACATAATACATGCTTATTTTATTTTTCATCCCTACAGAAAGGTAGAAGATGAGAATTCTGTCTCCTACTGTTGTTTTTCAAGGTGCCACTCAAATTTCTTGTACGTGTCTAGAAACTTGTGCATACAATAGAAGTA
CACTGTGGCTGGGCATGGTGGCTCATGCCTGTAATCCCAGCACTTTGTGAAGCTGAGGTGGGTGGATCACCTGAGGTCAGGGAGTTTGAGACCAGCCTGGCCAACATGATGAAACCCCGTCTTTACTAAAATTAGAAAAAATTAGCCAGG
CGTGGTGGTGTGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCATGAGAATCACTTGAACTCGGGTGGCAGAGGCTGCAGTGAGCTGAGATCATGCCACTGCATTCCAGCCTGCGCAGCTGAGCCAGACTCCATCTCCAAAAAAAAA
AAAAAAAAAAAAAAAAGATGTCCAATATATGTAACTTTTTTCTTTGGACACAAAAATTCCATTAGCTTTGTTTTCTCATTTTTACTTGTCATGATGTATGTCGAACACATTATTTTTAGTGTCTGGTGTTCCATTATACAGATGTCTCTC
TTGTTGGTTGAATTTTTGCATTCACAGACCCTCAAGTTGGATTCATATCTTTTTACACTAAGCATAAAGAAGACGGATTGGGGTCGGGTATGGTGGCTCACGCCTGTAATCCCAGCACTTCGGGAGGCTGAGGTGGGCGGATCACGAGGT
CAGGAGTTCGAGACCAGCCTGGCCAACATACTGAAACCCCGTCTCTAAAAATATGAAAAAAAAATTAGCCAGGCGTGGTGGTGCGCAGCTGTAGCCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGG
TTGCAGTGAGCATATTGCACCATTGCATTCCAGCCTGCACGACAGAGGAAGACGCCATTTCAAAAAAAAAAAAAAAAAGACGGATTGATTTTCTTCAGCAGTATCAAGTGGCACTTACCATCCACCCCTTTAACACCCAAACCATTCTAA
TCCATGTATACAGACCATCATCTGTTTCGTTATTGTGTTCTATAATGCAGCTTTGCGAGTTATGCAGTTTTGGTCCTCATGATATTTTTCTGATTGGTTTTTAATGTATTTTGTTCTAACGAGCCAACATTGTTATACATGTAATTTGTT
TATTTGCTAGATTGTACTCTTTCCCAAAGATGGGCTATGAACTAGCATCTACTTTCATTTTACCTATTTACCTGTAAACATTGAAAAAACTGAATCAAATGCAGTGATATCGGACCTAGTTTTATTGTTATGCCTTATAATGAATTTAAC
TTCACAGTTTTCTAAATGAGAGCATTTCCCAAAGACATCTTTATGGTCATAACCAGTTTCCCTTGGCATTTGATTTATTTTTATTTTTATTTATTTATCTTTTTGAGAAGGAGTTTCGCTCTTGTTGCCCAGGCTAGAGTGCAATGGCGT
GATCTCGGGTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCAAGTAGCTGGGATTACAGGCATGCACCACCACGCCCGACTAATTTGTATTTTTAGAGACGGGGTTTCTCCGTGTTGGTCAGGCTGGTCT
CAAACTTCCAACCTCAGGTGATCCGCCCGCCGTGGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACAGTGTCTGGCCTGATTTGTTTTTAAGAGCATTATTTTTCTGCTTTATTTTGTGACTTCAACATTTGACACAATTTTGGGT
GAATGGTTTGTGCATGGTGCCTGACATCGTGTTTTGATGTGTAGTATATGCCATAGGACATGTGAGACAAGATATGTCCCAACTTGACCTTGTTTTGTATTGTTTATGTCAAGGTGTTGAGTGTATTAGATATACTGTTGGGGCTCTGTG
TTCTAGCTCTGCCTTTTAGATAATAACCATGGTTAAATATTGCAATGTCCTGCATGTCTCCACACATGGGTTTTGTAACTGAGTCAGAATGATAAGTGATTAGTAAGCACATTTTTTCTCCTTTCAGGAAACCACTATTTTCCTTTTCTA
CATGCTGTTTTGTAAGTAGTACTTTTATGAAGGTTGTCTTCAAATGTTCGCATCTTCCATTTCTACTGCCCTTGGGTTATCCATCCTGTCATTTTGTGCCAATCACTTTTTTTTTTAACTTTTAAGTTCAGGGATGAAAGTGTAGATTTG
TTACATAGGTAAACTTGTGTCATGGGGTTGTTGTACAGATTATTTCATCACCCAGGTGTTAAGCCTAGTATGCACTAGTTGTTTTTCCTGATCCTCTCCCTGCTCCCACCCTCCACCCTCTGATAGGCCCCAGTGTGTGTTGTTCCCCTC
TGTGTGTCCATGTGTTCTCATCATTTAGCTCCCACTTACAAGTGAGAATGTGGTGTTTGGTTTTCTGTTCCTGCATTAGTTTGCTAAGGATAATGGCCTCGAGCTCCATCCAAGTCCCTGTAAAGGACATGATCTTGTACTTTTTTATGG
CTGCATAGTATTCTGTGGTGTATATGTACCACATTTTCTTTATCCAGTCTATCATTAGGCATTTAGGTTGATTCCATGTTTTTGCTATTGTGAATAGTGCTGCAATGAACATACATGTGCATGTCTTTTTATAATAGAATGATTTATATT
CTGTTGTGTATATACCCAGTAATGGGATTGCTGAGTTGAATGCTATTTCTGCCTTTAGGTCTTTGATGAATTGCCACACTGTCTTCCACAATGGTTGAACTAATTTACACTCCCACCAACGGTGAATAAGTGTTCACTTTTCTCCACAAC
CTTGTCAGCATCTATTATTTTTTGACTTTTTAGTAATAGCCATTCTGACTGCTCACATCTATTTTGTAAATAAAGTTTTATTGAAACATGGCCTTACCCATTTGTTTACATATATTCATGGCTGTTTTTGTGCCACAATGTCAGAGTTGT
CTTAAAGTAGACAGAGACTATCTGGCTGTAAAGCCTGAGATATATACTAACTGGTTCTTTATGTAAAAAGTTTGCTGACCACCTACTCTAAACGTTTTGCAGTGATGGTAGTGTTGGCAAAAAACCAAATAGCTTACCCTCTTTAAATTT
CCCTTTTACTTCTTACAAACTCCTAACACCATTTACGACTTTGTCATCAATATGGTCAACTAAGCTTGGTTTGCATGGCTCTACTTCCTTTCACCTTCCACTTAGGCAGTGTCTCCAAGTCCACTGCAGTTTCTATTTGTCTCCTGACTG
TTACTGTATCAGTTCTTACCTAAATAACATAACAACTGATCTCCCTACTTTTTGCCTATGCCCTCAAATGTGCTCATTGTTGATCTATCTCCCTGTTAGGTGTTCTTTTTCTCCTCTTTAGAAAGCAGCCAAGGAAACCAGGGTTCTCTC
AAAGTGGAAAATACTGGAACTTATGTACTGTTATCATAATGATAGTTGGTGTTTTGAATTATAAGAATGATTCCAGGTGGTTTCTAAATCATCCAATAAAGCTGTATTCACTCTGTA

>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133 length=1156nt 
 Breakpoint=337nt
GAGCCAGTGACAGGAGGGGCCGGGCTGGTACTTCAGGCGCCCAGGCCGGCGGGGCGCGCTCCGGCGGCTCCTGTCAGCGGCGGGTGCGGCGGATCCCAGGGCAGCCTTCGGGCGGCGGCGCTGCCTGGTGCGTCGCGGCGTGGTCCTCCG
GCGGCTGTCCGGGGCGGTAGGAGTTGGCTGCGGGATGTGCTCAGCCGGGGAGCTGCTGCGGGGCGGCGACGGCGGGGAACGCGACGAGGACGGGGACGCGCTGGCGGAGCGGGAGGCGGCAGGGACCGGGTGGGATCCCGGGGCGAGCCC
GCGGCGGCGCGGACAGCGGCCGAAGGAGAGCGAGCAGGAAACCACCCCTACTCCTAATCCCCCGACTACAGAAGAGGAGAAAACGGAATCTAATCAGGAGGTTGCTAACCCAGAACACTATATTAAACATCCCCTACAGAACAGATGGGC
ACTCTGGTTTTTTAAAAATGATAAAAGCAAAACTTGGCAAGCAAACCTGCGGCTGATCTCCAAGTTTGATACTGTTGAAGACTTTTGGGCTCTGTACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTACTCACTTTT
TAAGGATGGTATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGGGGAGGACGATGGCTAATTACATTGAACAAACAGCAGAGACGAAGTGACCTCGATCGCTTTTGGCTAGAGACACTTCTGTGCCTTATTGGAGAATCTTTTGATGA
CTACAGTGATGATGTATGTGGCGCTGTTGTTAATGTTAGAGCTAAAGGTGATAAGATAGCAATATGGACTACTGAATGTGAAAACAGAGAAGCTGTTACACATATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCAAAGATAGT
GATTGGTTATCAGTCCCACGCAGACACAGCTACTAAGAGCGGCTCCACCACTAAAAATAGGTTTGTTGTTTAAGAAGACACCTTCTGAGTATTCTCATAGGAGACTGCGTCAAGCAATCGAGATTTGGGAGCTGAACCAAAGCCTCTTCA
AAAAGCAGAGTGGACTGCATTTAAATTTGATTTCCATCTTAATGTTACTCAGATATAAGAGAAGTCTCATTCGCCTTTGTCTTGTACTTCTGTGTTCATTTTTTTT

>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133 length=1196nt 
 Breakpoint=337nt
GAGCCAGTGACAGGAGGGGCCGGGCTGGTACTTCAGGCGCCCAGGCCGGCGGGGCGCGCTCCGGCGGCTCCTGTCAGCGGCGGGTGCGGCGGATCCCAGGGCAGCCTTCGGGCGGCGGCGCTGCCTGGTGCGTCGCGGCGTGGTCCTCCG
GCGGCTGTCCGGGGCGGTAGGAGTTGGCTGCGGGATGTGCTCAGCCGGGGAGCTGCTGCGGGGCGGCGACGGCGGGGAACGCGACGAGGACGGGGACGCGCTGGCGGAGCGGGAGGCGGCAGGGACCGGGTGGGATCCCGGGGCGAGCCC
GCGGCGGCGCGGACAGCGGCCGAAGGAGAGCGAGCAGGAAACCACCCCTACTCCTAATCCCCCGACTACAGAAGAGGAGAAAACGGAATCTAATCAGGAGGTTGCTAACCCAGAACACTATATTAAACATCCCCTACAGAACAGATGGGC
ACTCTGGTTTTTTAAAAATGATAAAAGCAAAACTTGGCAAGCAAACCTGCGGCTGATCTCCAAGTTTGATACTGTTGAAGACTTTTGGGCTCTGTACAACCATATCCAGTTGTCTAGTAATTTAATGCCTGGCTGTGACTACTCACTTTT
TAAGGATGGTATTGAGCCTATGTGGGAAGATGAGAAAAACAAACGGGGAGGACGATGGCTAATTACATTGAACAAACAGCAGAGACGAAGTGACCTCGATCGCTTTTGGCTAGAGACAAGATGGGATCTTGCTATGTTGCCCAGGTTGGT
CTCAAACTTCTGGCCTCAAGTGATCCTCCCACTTCAGCCTCCCAAAGTGCTGGAATTACAGCTTCTGTGCCTTATTGGAGAATCTTTTGATGACTACAGTGATGATGTATGTGGCGCTGTTGTTAATGTTAGAGCTAAAGGTGATAAGAT
AGCAATATGGACTACTGAATGTGAAAACAGAGAAGCTGTTACACATATAGGGAGGGTATACAAGGAAAGGTTAGGACTTCCTCCAAAGATAGTGATTGGTTATCAGTCCCACGCAGACACAGCTACTAAGAGCGGCTCCACCACTAAAAA
TAGGTTTGTTGTTTAAGAAGACACCTTCTGAGTATTCTCATAGGAGACTGCGTCAAGCAATCGAGATTTGGGAGCTGAACCAAAGCCTCTTCAAAAAGCAGAGTGGACTGCATTTAAATTTGATTTCCATCTTAATGTTACTCAGA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for C4orf32_EIF4E

In-frame Fusion Protein Sequences.

>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133 length=300nt
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000450253_113066889_99823133 length=417nt
MDPPAMRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQT
DQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTF
FRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGVVKAAERSHPAKGGDGSAGLHQGAKRPYPCLNPPLTPLSLVKESEAPGSFFCFLTQQLKNGSR

>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133 length=300nt
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133 length=300nt
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for C4orf32_EIF4E

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.F94C;p.T116A_300_F177C;T199A length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLCKDGIEPMWEDEKNKRGGRWLIALNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.S82C_300_S165C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLCSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.F48S_300_F131S length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFSKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.N13K_300_N96K length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPKPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.E7D_300_E90D length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQDTTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.R128C_300_R211C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDCFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.S24C_300_S107C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTECNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.T22M_300_T105M length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKMESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.T68N_300_T151N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
NVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.R61Q_300_R144Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLQLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.R109W_300_R192W length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKWGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.D127N_300_D210N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.D90G_300_D173G length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCGYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.M101L_300_M184L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPLWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.W43L_300_W126L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRLALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.D90Y_300_D173Y length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCYYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.A58P_300_A141P length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQPNLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.K21Q_300_K104Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEQTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000280892_113066889_99823133_3-gene_p.F47L_300_F130L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWLFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.F94C;p.T116A_300_F177C;T199A length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLCKDGIEPMWEDEKNKRGGRWLIALNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.S82C_300_S165C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLCSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.F48S_300_F131S length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFSKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.N13K_300_N96K length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPKPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.E7D_300_E90D length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQDTTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.R128C_300_R211C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDCFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.S24C_300_S107C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTECNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.T22M_300_T105M length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKMESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.T68N_300_T151N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
NVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.R61Q_300_R144Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLQLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.R109W_300_R192W length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKWGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.D127N_300_D210N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.D90G_300_D173G length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCGYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.M101L_300_M184L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPLWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.W43L_300_W126L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRLALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.D90Y_300_D173Y length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCYYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.A58P_300_A141P length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQPNLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.K21Q_300_K104Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEQTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000504432_113066889_99823133_3-gene_p.F47L_300_F130L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWLFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.F94C;p.T116A_300_F177C;T199A length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLCKDGIEPMWEDEKNKRGGRWLIALNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.S82C_300_S165C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLCSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.F48S_300_F131S length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFSKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.N13K_300_N96K length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPKPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.E7D_300_E90D length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQDTTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.R128H_300_R211H length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDHFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.R128C_300_R211C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDCFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.S24C_300_S107C length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTECNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.T22M_300_T105M length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKMESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.T68N_300_T151N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
NVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.R61Q_300_R144Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLQLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.R109W_300_R192W length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKWGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.D127N_300_D210N length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLNRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.D90G_300_D173G length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCGYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.M101L_300_M184L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPLWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.W43L_300_W126L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRLALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.D90Y_300_D173Y length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCYYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.A58P_300_A141P length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQPNLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.K21Q_300_K104Q length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEQTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV


>C4orf32_EIF4E_ENST00000309733_ENST00000505992_113066889_99823133_3-gene_p.F47L_300_F130L length=300AA
MSAAGAADPRAAFGRRRCLVRRGVVLRRLSGAVGVGCGMCSAGELLRGGDGGERDEDGDALAEREAAGTGWDPGASPRRRGQRPKESEQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWLFKNDKSKTWQANLRLISKFD
TVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-06-5416-01A	3-gene	p.F94C;p.T116A	300	F177C;T199A
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-17-Z000-01A	3-gene	p.S82C	300	S165C
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-2W-A8YY-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-62-8402-01A	3-gene	p.F48S	300	F131S
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-A3-3320-01A	3-gene	p.N13K	300	N96K
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-AA-A00N-01A	3-gene	p.E7D	300	E90D
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-AX-A0J1-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-BF-A3DM-01A	3-gene	p.R128C	300	R211C
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-BR-6458-01A	3-gene	p.S24C	300	S107C
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-CK-6746-01A	3-gene	p.T22M	300	T105M
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-DU-6392-01A	3-gene	p.T68N	300	T151N
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-EA-A3HS-01A	3-gene	p.R61Q	300	R144Q
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-EO-A22U-01A	3-gene	p.R109W	300	R192W
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-F5-6814-01A	3-gene	p.D127N	300	D210N
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-F7-A624-01A	3-gene	p.D90G	300	D173G
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-FR-A3R1-01A	3-gene	p.M101L	300	M184L
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-GN-A265-06A	3-gene	p.W43L	300	W126L
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-KQ-A41N-01A	3-gene	p.D90Y	300	D173Y
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-MP-A4TJ-01A	3-gene	p.A58P	300	A141P
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-VP-A87J-01A	3-gene	p.K21Q	300	K104Q
ENST00000309733_ENST00000280892_113066889_99823133	TCGA-WY-A85D-01A	3-gene	p.F47L	300	F130L
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-06-5416-01A	3-gene	p.F94C;p.T116A	300	F177C;T199A
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-17-Z000-01A	3-gene	p.S82C	300	S165C
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-2W-A8YY-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-62-8402-01A	3-gene	p.F48S	300	F131S
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-A3-3320-01A	3-gene	p.N13K	300	N96K
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-AA-A00N-01A	3-gene	p.E7D	300	E90D
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-AX-A0J1-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-BF-A3DM-01A	3-gene	p.R128C	300	R211C
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-BR-6458-01A	3-gene	p.S24C	300	S107C
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-CK-6746-01A	3-gene	p.T22M	300	T105M
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-DU-6392-01A	3-gene	p.T68N	300	T151N
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-EA-A3HS-01A	3-gene	p.R61Q	300	R144Q
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-EO-A22U-01A	3-gene	p.R109W	300	R192W
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-F5-6814-01A	3-gene	p.D127N	300	D210N
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-F7-A624-01A	3-gene	p.D90G	300	D173G
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-FR-A3R1-01A	3-gene	p.M101L	300	M184L
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-GN-A265-06A	3-gene	p.W43L	300	W126L
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-KQ-A41N-01A	3-gene	p.D90Y	300	D173Y
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-MP-A4TJ-01A	3-gene	p.A58P	300	A141P
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-VP-A87J-01A	3-gene	p.K21Q	300	K104Q
ENST00000309733_ENST00000504432_113066889_99823133	TCGA-WY-A85D-01A	3-gene	p.F47L	300	F130L
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-06-5416-01A	3-gene	p.F94C;p.T116A	300	F177C;T199A
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-17-Z000-01A	3-gene	p.S82C	300	S165C
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-2W-A8YY-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-62-8402-01A	3-gene	p.F48S	300	F131S
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-A3-3320-01A	3-gene	p.N13K	300	N96K
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-AA-A00N-01A	3-gene	p.E7D	300	E90D
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-AX-A0J1-01A	3-gene	p.R128H	300	R211H
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-BF-A3DM-01A	3-gene	p.R128C	300	R211C
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-BR-6458-01A	3-gene	p.S24C	300	S107C
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-CK-6746-01A	3-gene	p.T22M	300	T105M
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-DU-6392-01A	3-gene	p.T68N	300	T151N
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-EA-A3HS-01A	3-gene	p.R61Q	300	R144Q
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-EO-A22U-01A	3-gene	p.R109W	300	R192W
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-F5-6814-01A	3-gene	p.D127N	300	D210N
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-F7-A624-01A	3-gene	p.D90G	300	D173G
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-FR-A3R1-01A	3-gene	p.M101L	300	M184L
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-GN-A265-06A	3-gene	p.W43L	300	W126L
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-KQ-A41N-01A	3-gene	p.D90Y	300	D173Y
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-MP-A4TJ-01A	3-gene	p.A58P	300	A141P
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-VP-A87J-01A	3-gene	p.K21Q	300	K104Q
ENST00000309733_ENST00000505992_113066889_99823133	TCGA-WY-A85D-01A	3-gene	p.F47L	300	F130L

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for C4orf32_EIF4E

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		COAD	TCGA-AA-3858	C4orf32	chr4	113066889	+	EIF4E	chr4	99823133	-

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for C4orf32_EIF4E

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status