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Fusion gene:C9orf85_FXN (FusionGDB2 ID:HG138241TG2395) |
Fusion Gene Summary for C9orf85_FXN |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C9orf85_FXN | Fusion gene ID: hg138241tg2395 | Hgene | Tgene | Gene symbol | C9orf85 | FXN | Gene ID | 138241 | 2395 |
| Gene name | chromosome 9 open reading frame 85 | frataxin | |
| Synonyms | - | CyaY|FA|FARR|FRDA|X25 | |
| Cytomap | 9q21.13 | 9q21.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | uncharacterized protein C9orf85 | frataxin, mitochondrialFriedreich ataxia protein | |
| Modification date | 20240316 | 20240305 | |
| UniProtAcc | Q96MD7 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000334731, ENST00000377031, ENST00000486911, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 4 X 2=32 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 14 X 9=504 |
| # samples | 6 | 19 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(6/32*10)=0.906890595608518 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(19/504*10)=-1.40742431516897 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: C9orf85 [Title/Abstract] AND FXN [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | C9orf85(74526752)-FXN(71679853), # samples:1 | ||
| Fusion gene breakpoints across C9orf85 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FXN (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Breakpoints for C9orf85_FXN |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| C9orf85 | chr9 | 74526752 | FXN | chr9 | 74526752 |
| C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679854 |
| C9ORF85 | chr9 | 71911836 | FXN | chr9 | 69064938 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for C9orf85_FXN |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| C9orf85-FXN | Promoter / Enhancer Hijacking M6 | Promoter swap alters frataxin expression, modifying mitochondrial iron-sulfur cluster assembly and oxidative stress defense. | Iron chelators; ROS-inducing agents | Metabolic carcinomas |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| C9orf85-FXN | Promoter / Enhancer Hijacking M6 | Promoter swap alters frataxin expression, modifying mitochondrial iron-sulfur cluster assembly and oxidative stress defense. | Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 41005206; Title: NFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphoma.; PMID: 39184439; Title: FXN targeting induces cell death in ovarian cancer stem-like cells through PRDX3-Mediated oxidative stress. | Iron chelators; ROS-inducing agents | Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 39184439; Title: FXN targeting induces cell death in ovarian cancer stem-like cells through PRDX3-Mediated oxidative stress.; PMID: 41005206; Title: NFS1, together with FXN, protects cells from ferroptosis and DNA damage in diffuse large B-cell lymphoma. | Metabolic carcinomas |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C9orf85 | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FXN | GO:0010722 | regulation of ferrochelatase activity | 15123683 |
| Tgene | FXN | GO:0016226 | iron-sulfur cluster assembly | 29491838 |
| Tgene | FXN | GO:0016540 | protein autoprocessing | 12785837 |
| Tgene | FXN | GO:0018283 | iron incorporation into metallo-sulfur cluster | 12785837 |
| Tgene | FXN | GO:0044571 | [2Fe-2S] cluster assembly | 24971490|29576242 |
| Tgene | FXN | GO:0044572 | [4Fe-4S] cluster assembly | 29576242 |
| Tgene | FXN | GO:0051349 | positive regulation of lyase activity | 20053667 |
| Tgene | FXN | GO:0070301 | cellular response to hydrogen peroxide | 15641778 |
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Fusion Genomic Features for C9orf85_FXN |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + | 1.50e-03 | 9.98e-01 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for C9orf85_FXN |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000334731 | ENST00000377270 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000334731 | ENST00000396364 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000334731 | ENST00000396366 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000334731 | ENST00000498653 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000377031 | ENST00000377270 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000377031 | ENST00000396364 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000377031 | ENST00000396366 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000377031 | ENST00000498653 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000486911 | ENST00000377270 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000486911 | ENST00000396364 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000486911 | ENST00000396366 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| In-frame | ENST00000486911 | ENST00000498653 | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679853 | + |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000334731 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 95 |
| ENST00000334731 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 318 |
| ENST00000334731 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 120 |
| ENST00000334731 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 106 |
| ENST00000377031 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 95 |
| ENST00000377031 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 120 |
| ENST00000377031 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 120 |
| ENST00000377031 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 292 | 106 |
| ENST00000486911 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 176 | 81 |
| ENST00000486911 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 176 | 120 |
| ENST00000486911 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 176 | 120 |
| ENST00000486911 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 176 | 106 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000334731 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 3.52e-01 | 6.48e-01 |
| ENST00000334731 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 4.29e-01 | 5.71e-01 |
| ENST00000334731 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 2.17e-01 | 7.83e-01 |
| ENST00000334731 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 8.18e-02 | 9.18e-01 |
| ENST00000377031 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 3.52e-01 | 6.48e-01 |
| ENST00000377031 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 4.29e-01 | 5.71e-01 |
| ENST00000377031 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 2.17e-01 | 7.83e-01 |
| ENST00000377031 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 8.18e-02 | 9.18e-01 |
| ENST00000486911 | ENST00000377270 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 3.56e-01 | 6.44e-01 |
| ENST00000486911 | ENST00000396364 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 4.14e-01 | 5.86e-01 |
| ENST00000486911 | ENST00000396366 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 1.49e-01 | 8.51e-01 |
| ENST00000486911 | ENST00000498653 | C9orf85 | chr9 | 74526752 | FXN | chr9 | 71679853 | 9.27e-02 | 9.07e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
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Fusion Protein Retained/Non-Retained Functional Features for C9orf85_FXN |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
C9orf85_FXN_chr9-74526752_chr9-71679853.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for C9orf85_FXN |
| In-frame Fusion Transcript Sequences. |
>C9orf85_FXN_ENST00000334731_ENST00000377270_74526752_71679853 length=1992nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTC CCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTAT GCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGA TTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCA TTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATT GAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGTGTGTATATATATTTTTTC AATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAAATCATGGAGCTGAGGAGGTGCCTTGTAAACATGA AGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAGAGCCCTGGTCCTAGACATAGTTCAGCCACAAAGTAGTTGTCCCTTTGTGGACAAGTTTCCCAAATTCCCTGGACCTCTGCTTCCCCATCTGTTAAATGAGAGAATAGAG TATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTGCCCTATCGTGATTTCAGT TGAATTCATGTGAAAATAATAGCCATCCTTGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGATGAAACCCCGTCTCTACT AAAAATACAAAAAATTAGCCGGGCATGATGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGCGGAAGAATCGCTTGAACCCAGAGGTGGAGGTTGCAGTGAGCCGAGATCGTGCCATTGCACTGTAACCTGGGTGACTGAGCA AAACTCTGTCTCAAAATAATAATAACAATATAATAATAATAA >C9orf85_FXN_ENST00000334731_ENST00000396364_74526752_71679853 length=668nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTTAACGTGGCTCCTGTGGCTGTTCCATCCCTGAGGAAAAGTGAGGACCATGCTCTCCAA ACAGGCCATGTGCTGGACTACCTCTGTTTCTGTCTCCTGGGATTCCAATCAGCAAGTGAGCAACGAAGCAACCCAGACAGTGTGGTTCATAGGATGGCTGGGTAAGTGGCTGTTTGTTTTTTCCTTACTGTGGATATGTATCAGTGAAGG AATCTGTAGAACATTCTTGATGGGAACATTTAGTCATATCAAGTCAATAAATTAATGTTTAGGCTGGG >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853 length=809nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTATGTAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGAC GGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGC TTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCT ATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTAT >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853 length=884nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTC CCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTAT GCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGA TTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAA >C9orf85_FXN_ENST00000377031_ENST00000377270_74526752_71679853 length=1992nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTC CCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTAT GCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGA TTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAATTGTCTTCACTCTTCA TTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTTTCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATT GAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATATTCACATACGTGTCTGTGTGTATATATATTTTTTC AATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAAATCATGGAGCTGAGGAGGTGCCTTGTAAACATGA AGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAGAGCCCTGGTCCTAGACATAGTTCAGCCACAAAGTAGTTGTCCCTTTGTGGACAAGTTTCCCAAATTCCCTGGACCTCTGCTTCCCCATCTGTTAAATGAGAGAATAGAG TATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAACATTGTTATTGGTGTTGCCCTATCGTGATTTCAGT TGAATTCATGTGAAAATAATAGCCATCCTTGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGATGAAACCCCGTCTCTACT AAAAATACAAAAAATTAGCCGGGCATGATGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGCGGAAGAATCGCTTGAACCCAGAGGTGGAGGTTGCAGTGAGCCGAGATCGTGCCATTGCACTGTAACCTGGGTGACTGAGCA AAACTCTGTCTCAAAATAATAATAACAATATAATAATAATAA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853 length=668nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTTAACGTGGCTCCTGTGGCTGTTCCATCCCTGAGGAAAAGTGAGGACCATGCTCTCCAA ACAGGCCATGTGCTGGACTACCTCTGTTTCTGTCTCCTGGGATTCCAATCAGCAAGTGAGCAACGAAGCAACCCAGACAGTGTGGTTCATAGGATGGCTGGGTAAGTGGCTGTTTGTTTTTTCCTTACTGTGGATATGTATCAGTGAAGG AATCTGTAGAACATTCTTGATGGGAACATTTAGTCATATCAAGTCAATAAATTAATGTTTAGGCTGGG >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853 length=809nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTATGTAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGAC GGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGC TTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCT ATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTAT >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853 length=884nt Breakpoint=292nt GGGAGGGCAGAGCGATGCTCTTTGACCTCCCAGAAGAGTCACGTGGGCTGACCCAGAGCCGGGGCGGAAAGGCTGCGTTTGTTTCTTCCGGGTCATTGACAGAAGCGTCAATTCCTGGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCC TTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACAAGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGT CTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTC CCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTAT GCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGA TTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAATTCCAGGAGGGAAAATGAA >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853 length=1876nt Breakpoint=176nt GGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCCTTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACA AGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTG GGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATT AAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTG CCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAAT TCCAGGAGGGAAAATGAATTGTCTTCACTCTTCATTCTTTGAAGGATTTACTGCAAGAAGTACATGAAGAGCAGCTGGTCAACCTGCTCACTGTTCTATCTCCAAATGAGACACATTAAAGGGTAGCCTACAAATGTTTTCAGGCTTCTT TCAAAGTGTAAGCACTTCTGAGCTCTTTAGCATTGAAGTGTCGAAAGCAACTCACACGGGAAGATCATTTCTTATTTGTGCTCTGTGACTGCCAAGGTGTGGCCTGCACTGGGTTGTCCAGGGAGACCTAGTGCTGTTTCTCCCACATAT TCACATACGTGTCTGTGTGTATATATATTTTTTCAATTTAAAGGTTAGTATGGAATCAGCTGCTACAAGAATGCAAAAAATCTTCCAAAGACAAGAAAAGAGGAAAAAAAGCCGTTTTCATGAGCTGAGTGATGTAGCGTAACAAACAAA ATCATGGAGCTGAGGAGGTGCCTTGTAAACATGAAGGGGCAGATAAAGGAAGGAGATACTCATGTTGATAAAGAGAGCCCTGGTCCTAGACATAGTTCAGCCACAAAGTAGTTGTCCCTTTGTGGACAAGTTTCCCAAATTCCCTGGACC TCTGCTTCCCCATCTGTTAAATGAGAGAATAGAGTATGGTTGATTCCCAGCATTCAGTGGTCCTGTCAAGCAACCTAACAGGCTAGTTCTAATTCCCTATTGGGTAGATGAGGGGATGACAAAGAACAGTTTTTAAGCTATATAGGAAAC ATTGTTATTGGTGTTGCCCTATCGTGATTTCAGTTGAATTCATGTGAAAATAATAGCCATCCTTGGCCTGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACC AGCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGATGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAAGCGGAAGAATCGCTTGAACCCAGAGGTGGAGGTTGCAGTGAGCCGAGAT CGTGCCATTGCACTGTAACCTGGGTGACTGAGCAAAACTCTGTCTCAAAATAATAATAACAATATAATAATAATAA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853 length=552nt Breakpoint=176nt GGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCCTTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACA AGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTTAACGTGGCTCCTGTGGCTGTTCC ATCCCTGAGGAAAAGTGAGGACCATGCTCTCCAAACAGGCCATGTGCTGGACTACCTCTGTTTCTGTCTCCTGGGATTCCAATCAGCAAGTGAGCAACGAAGCAACCCAGACAGTGTGGTTCATAGGATGGCTGGGTAAGTGGCTGTTTG TTTTTTCCTTACTGTGGATATGTATCAGTGAAGGAATCTGTAGAACATTCTTGATGGGAACATTTAGTCATATCAAGTCAATAAATTAATGTTTAGGCTGGG >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853 length=693nt Breakpoint=176nt GGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCCTTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACA AGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGGTATGTAGTGGACCTAAGCGTTATGA CTGGACTGGGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTA AGGACATTAAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTC CTACCTTGCCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTAT >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853 length=768nt Breakpoint=176nt GGGAGTAGTTCGTTGGTTTTCTTTCCCCTCATCCTTTTGCCTGCTCCCGGCGAGGGGTGGCTTTGATTTCGGCGATGAGCTCCCAGAAAGGCAACGTGGCTCGTTCCAGACCTCAGAAGCACCAGAATACGTTTAGCTTCAAAAATGACA AGTTCGATAAAAGTGTGCAGACCAAGAGTGGTGTCTTAACTGTCAAACTGGGTGGAGATCTAGGAACCTATGTGATCAACAAGCAGACGCCAAACAAGCAAATCTGGCTATCTTCTCCATCCAGTGGACCTAAGCGTTATGACTGGACTG GGAAAAACTGGGTGTACTCCCACGACGGCGTGTCCCTCCATGAGCTGCTGGCCGCAGAGCTCACTAAAGCCTTAAAAACCAAACTGGACTTGTCTTCCTTGGCCTATTCCGGAAAAGATGCTTGATGCCCAGCCCCGTTTTAAGGACATT AAAAGCTATCAGGCCAAGACCCCAGCTTCATTATGCAGCTGAGGTCTGTTTTTTGTTGTTGTTGTTGTTTATTTTTTTTATTCCTGCTTTTGAGGACAGTTGGGCTATGTGTCACAGCTCTGTAGAAAGAATGTGTTGCCTCCTACCTTG CCCCCAAGTTCTGATTTTTAATTTCTATGGAAGATTTTTTGGATTGTCGGATTTCCTCCCTCACATGATACCCCTTATCTTTTATAATGTCTTATGCCTATACCTGAATATAACAACCTTTAAAAAAGCAAAATAATAAGAAGGAAAAAT TCCAGGAGGGAAAATGAA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
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Fusion Protein Sequence for C9orf85_FXN |
| In-frame Fusion Protein Sequences. |
>C9orf85_FXN_ENST00000334731_ENST00000377270_74526752_71679853 length=95nt MHTFIELVIFEAKRILVLLRSGTSHVAFLGAHRRNQSHPSPGAGKRMRGKKTNELLPGIDASVNDPEETNAAFPPRLWVSPRDSSGRSKSIALPS >C9orf85_FXN_ENST00000334731_ENST00000396364_74526752_71679853 length=318nt MRMRRPLAGGGKSWGIAHFYKVTKWIGVNRRPRKRKRREKEEVFEKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGR ENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAE MKLRPSNFRNLEGRRKRA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853 length=120nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853 length=106nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000377270_74526752_71679853 length=95nt MHTFIELVIFEAKRILVLLRSGTSHVAFLGAHRRNQSHPSPGAGKRMRGKKTNELLPGIDASVNDPEETNAAFPPRLWVSPRDSSGRSKSIALPS >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853 length=120nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853 length=120nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853 length=106nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853 length=81nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853 length=120nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853 length=120nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853 length=106nt MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for C9orf85_FXN |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.N7I_120_N11I length=120AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.T19M_120_T23M length=120AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.T33I_120_T37I length=120AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.F22I_120_F26I length=120AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.N7I_106_N11I length=106AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.T19M_106_T23M length=106AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.T33I_106_T37I length=106AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.F22I_106_F26I length=106AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000334731_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.N7I_120_N11I length=120AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.T19M_120_T23M length=120AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.T33I_120_T37I length=120AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.F22I_120_F26I length=120AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396364_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.N7I_120_N11I length=120AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.T19M_120_T23M length=120AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.T33I_120_T37I length=120AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.F22I_120_F26I length=120AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.N7I_106_N11I length=106AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.T19M_106_T23M length=106AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.T33I_106_T37I length=106AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.F22I_106_F26I length=106AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000377031_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.N7D_81_N11D length=81AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.N7I_81_N11I length=81AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.T19M_81_T23M length=81AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.T33I_81_T37I length=81AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.F22I_81_F26I length=81AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000377270_74526752_71679853_5-gene_p.N7D_81_N11D length=81AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRLTWLLWLFHP >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.N7I_120_N11I length=120AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.T19M_120_T23M length=120AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.T33I_120_T37I length=120AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.F22I_120_F26I length=120AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396364_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.N7I_120_N11I length=120AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.T19M_120_T23M length=120AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.T33I_120_T37I length=120AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.F22I_120_F26I length=120AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000396366_74526752_71679853_5-gene_p.N7D_120_N11D length=120AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYSGKDA >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.N7I_106_N11I length=106AA MISAMSSQKGIVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.T19M_106_T23M length=106AA MISAMSSQKGNVARSRPQKHQNMFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.T33I_106_T37I length=106AA MISAMSSQKGNVARSRPQKHQNTFSFKNDKFDKSVQIKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.F22I_106_F26I length=106AA MISAMSSQKGNVARSRPQKHQNTFSIKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP >C9orf85_FXN_ENST00000486911_ENST00000498653_74526752_71679853_5-gene_p.N7D_106_N11D length=106AA MISAMSSQKGDVARSRPQKHQNTFSFKNDKFDKSVQTKSGVLTVKLGGDLGTYVINKQTPNKQIWLSSPSRYVVDLSVMTGLGKTGCTPTTACPSMSCWPQSSLKP |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 120 | N11D |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 120 | N11I |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 120 | T23M |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 120 | T37I |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 120 | F26I |
| ENST00000334731_ENST00000396366_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 120 | N11D |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 106 | N11D |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 106 | N11I |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 106 | T23M |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 106 | T37I |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 106 | F26I |
| ENST00000334731_ENST00000498653_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 106 | N11D |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 120 | N11D |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 120 | N11I |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 120 | T23M |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 120 | T37I |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 120 | F26I |
| ENST00000377031_ENST00000396364_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 120 | N11D |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 120 | N11D |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 120 | N11I |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 120 | T23M |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 120 | T37I |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 120 | F26I |
| ENST00000377031_ENST00000396366_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 120 | N11D |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 106 | N11D |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 106 | N11I |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 106 | T23M |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 106 | T37I |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 106 | F26I |
| ENST00000377031_ENST00000498653_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 106 | N11D |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 81 | N11D |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 81 | N11I |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 81 | T23M |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 81 | T37I |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 81 | F26I |
| ENST00000486911_ENST00000377270_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 81 | N11D |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 120 | N11D |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 120 | N11I |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 120 | T23M |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 120 | T37I |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 120 | F26I |
| ENST00000486911_ENST00000396364_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 120 | N11D |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 120 | N11D |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 120 | N11I |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 120 | T23M |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 120 | T37I |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 120 | F26I |
| ENST00000486911_ENST00000396366_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 120 | N11D |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-AA-3672-01A | 5-gene | p.N7D | 106 | N11D |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-B0-5691-01A | 5-gene | p.N7I | 106 | N11I |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-B5-A3FA-01A | 5-gene | p.T19M | 106 | T23M |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-BR-8360-01A | 5-gene | p.T33I | 106 | T37I |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-GC-A3RC-01A | 5-gene | p.F22I | 106 | F26I |
| ENST00000486911_ENST00000498653_74526752_71679853 | TCGA-Z2-A8RT-06A | 5-gene | p.N7D | 106 | N11D |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
Top |
Fusion Gene Exprssed Samples for C9orf85_FXN |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | SKCM | TCGA-FS-A1ZP-06A | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 74526752 | + | |
| WashU | SKCM | TCGA-FS-A1ZP-06A | C9orf85 | chr9 | 74526752 | + | FXN | chr9 | 71679854 | + | |
| cBioPortal | SKCM_TCGA_PAN_CAN_ATLAS_2018 | SKCM | TCGA-FS-A1ZP-06 | C9ORF85 | chr9 | 71911836 | FXN | chr9 | 69064938 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
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Related Drugs for C9orf85_FXN |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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