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Fusion gene:CTSZ_ZHX3 (FusionGDB2 ID:HG1522TG23051) |
Fusion Gene Summary for CTSZ_ZHX3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CTSZ_ZHX3 | Fusion gene ID: hg1522tg23051 | Hgene | Tgene | Gene symbol | CTSZ | ZHX3 | Gene ID | 1522 | 23051 |
| Gene name | cathepsin Z | zinc fingers and homeoboxes 3 | |
| Synonyms | CTSX | TIX1 | |
| Cytomap | 20q13.32 | 20q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cathepsin Zcarboxypeptidase LBcathepsin B2cathepsin IVcathepsin Pcathepsin Xcathepsin Ycathepsin Z1cysteine-type carboxypeptidaselysosomal carboxypeptidase Bpreprocathepsin P | zinc fingers and homeoboxes protein 3triple homeobox 1triple homeobox protein 1zinc finger and homeodomain protein 3 | |
| Modification date | 20240305 | 20240407 | |
| UniProtAcc | Q9UBR2 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000217131, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 5 X 7 X 4=140 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 8 X 7=224 |
| # samples | 169 | 123 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(169/140*10)=3.59352451422458 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(123/224*10)=2.457087678169 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CTSZ [Title/Abstract] AND ZHX3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CTSZ(57572657)-ZHX3(39813841), # samples:1 | ||
| Fusion gene breakpoints across CTSZ (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ZHX3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Breakpoints for CTSZ_ZHX3 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 |
| CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 |
| CTSZ | chr20 | 57571694 | ZHX3 | chr20 | 39813841 |
| CTSZ | chr20 | 58996639 | ZHX3 | chr20 | 41185201 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for CTSZ_ZHX3 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| CTSZ-ZHX3 | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity M2 | Fusion pairs cathepsin Z to ZHX3 zinc-finger homeobox transcription factor, driving aberrant transactivation of survival and EMT genes. | Transcriptional CDK inhibitors; epigenetic modulators | Invasive solid tumors |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| CTSZ-ZHX3 | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity M2 | Fusion pairs cathepsin Z to ZHX3 zinc-finger homeobox transcription factor, driving aberrant transactivation of survival and EMT genes. | Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 33440047; Title: ZHX3 promotes the progression of urothelial carcinoma of the bladder via repressing of RGS2 and is a novel substrate of TRIM21. | Transcriptional CDK inhibitors; epigenetic modulators | Invasive solid tumors | Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 33440047; Title: ZHX3 promotes the progression of urothelial carcinoma of the bladder via repressing of RGS2 and is a novel substrate of TRIM21.; PMID: 28152006; Title: Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma. |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CTSZ | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ZHX3 | GO:0045892 | negative regulation of DNA-templated transcription | 12659632 |
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Fusion Genomic Features for CTSZ_ZHX3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - | 4.34e-04 | 1.00e+00 |
| CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - | 4.67e-06 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for CTSZ_ZHX3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000217131 | ENST00000309060 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000432768 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000540170 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000544979 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000557816 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000558993 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000559234 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| Frame-shift | ENST00000217131 | ENST00000560361 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000309060 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000432768 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000540170 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000544979 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000557816 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000558993 | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000559234 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| In-frame | ENST00000217131 | ENST00000560361 | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000217131 | ENST00000309060 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 920 | 267 |
| ENST00000217131 | ENST00000432768 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 920 | 375 |
| ENST00000217131 | ENST00000540170 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 757 | 375 |
| ENST00000217131 | ENST00000544979 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 920 | 375 |
| ENST00000217131 | ENST00000557816 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 757 | 236 |
| ENST00000217131 | ENST00000558993 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 920 | 375 |
| ENST00000217131 | ENST00000559234 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 757 | 236 |
| ENST00000217131 | ENST00000560361 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 757 | 236 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000217131 | ENST00000309060 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 2.13e-02 | 9.79e-01 |
| ENST00000217131 | ENST00000432768 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 2.56e-04 | 1.00e+00 |
| ENST00000217131 | ENST00000540170 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 5.97e-02 | 9.40e-01 |
| ENST00000217131 | ENST00000544979 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 5.01e-04 | 9.99e-01 |
| ENST00000217131 | ENST00000557816 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 7.91e-04 | 9.99e-01 |
| ENST00000217131 | ENST00000558993 | CTSZ | chr20 | 57571693 | ZHX3 | chr20 | 39813841 | 4.95e-04 | 1.00e+00 |
| ENST00000217131 | ENST00000559234 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 1.80e-02 | 9.82e-01 |
| ENST00000217131 | ENST00000560361 | CTSZ | chr20 | 57572657 | ZHX3 | chr20 | 39813841 | 7.97e-04 | 9.99e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
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Fusion Protein Retained/Non-Retained Functional Features for CTSZ_ZHX3 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
| No matching images found for ${hg}_${tg}. |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 42_58 | 953.3333333333334 | 957.0 | Compositional bias | Low complexity |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 666_677 | 953.3333333333334 | 957.0 | Compositional bias | Basic and acidic residues |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 679_695 | 953.3333333333334 | 957.0 | Compositional bias | Acidic residues |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 42_58 | 953.3333333333334 | 2914.3333333333335 | Compositional bias | Low complexity |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 666_677 | 953.3333333333334 | 2914.3333333333335 | Compositional bias | Basic and acidic residues |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 679_695 | 953.3333333333334 | 2914.3333333333335 | Compositional bias | Acidic residues |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 304_363 | 953.3333333333334 | 957.0 | DNA binding | Homeobox 1 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 494_553 | 953.3333333333334 | 957.0 | DNA binding | Homeobox 2 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 612_671 | 953.3333333333334 | 957.0 | DNA binding | Homeobox 3 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 764_823 | 953.3333333333334 | 957.0 | DNA binding | Homeobox 4 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 835_894 | 953.3333333333334 | 957.0 | DNA binding | Homeobox 5 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 304_363 | 953.3333333333334 | 2914.3333333333335 | DNA binding | Homeobox 1 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 494_553 | 953.3333333333334 | 2914.3333333333335 | DNA binding | Homeobox 2 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 612_671 | 953.3333333333334 | 2914.3333333333335 | DNA binding | Homeobox 3 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 764_823 | 953.3333333333334 | 2914.3333333333335 | DNA binding | Homeobox 4 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 835_894 | 953.3333333333334 | 2914.3333333333335 | DNA binding | Homeobox 5 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 1_107 | 953.3333333333334 | 957.0 | Region | Note=Required for nuclear localization |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 22_66 | 953.3333333333334 | 957.0 | Region | Disordered |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 303_502 | 953.3333333333334 | 957.0 | Region | Note=Required for repressor activity |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 497_555 | 953.3333333333334 | 957.0 | Region | Note=Required for nuclear localization |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 598_618 | 953.3333333333334 | 957.0 | Region | Disordered |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 666_695 | 953.3333333333334 | 957.0 | Region | Disordered |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 890_956 | 953.3333333333334 | 957.0 | Region | Disordered |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 1_107 | 953.3333333333334 | 2914.3333333333335 | Region | Note=Required for nuclear localization |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 22_66 | 953.3333333333334 | 2914.3333333333335 | Region | Disordered |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 303_502 | 953.3333333333334 | 2914.3333333333335 | Region | Note=Required for repressor activity |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 497_555 | 953.3333333333334 | 2914.3333333333335 | Region | Note=Required for nuclear localization |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 598_618 | 953.3333333333334 | 2914.3333333333335 | Region | Disordered |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 666_695 | 953.3333333333334 | 2914.3333333333335 | Region | Disordered |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 890_956 | 953.3333333333334 | 2914.3333333333335 | Region | Disordered |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 109_132 | 953.3333333333334 | 957.0 | Zinc finger | Note=C2H2-type 2 |
| Tgene | ZHX3 | chr20:57571693 | chr20:39813841 | ENST00000309060 | Q9H4I2 | 3 | 5 | 77_100 | 953.3333333333334 | 957.0 | Zinc finger | Note=C2H2-type 1 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 109_132 | 953.3333333333334 | 2914.3333333333335 | Zinc finger | Note=C2H2-type 2 |
| Tgene | ZHX3 | chr20:57572657 | chr20:39813841 | ENST00000540170 | Q9H4I2 | 2 | 5 | 77_100 | 953.3333333333334 | 2914.3333333333335 | Zinc finger | Note=C2H2-type 1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for CTSZ_ZHX3 |
| In-frame Fusion Transcript Sequences. |
>CTSZ_ZHX3_ENST00000217131_ENST00000309060_57571693_39813841 length=7674nt Breakpoint=920nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGG GAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATA GTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGCATTGTCAGTTACGTCAT CTCTAAAAATGACCTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGCAGGGAAGTTATAGGCACAAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTT GAAGAGATCTCTGCTGCATTAAGTGATGACCGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTCAAAAAATGGACTGGCAATGTGATTAGCGTTGGATGCTTTACCATTCT CTTTAGTTGTTACCGTAATTCTGCTTTTTCATGGGAGTTTGAATCATGGACCATAACTTTTCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTTTTTAATCTAGACATGTT TGGAGTGAGAGAAAGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGCTTTGACCACTGCGGTTTTCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACA CTGGCCCATTAGTAAGGGTGAAGGCTGGAGGGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCTGGCAGAACACCCAGAGTGCCCGTGGCTCCCACCCCAGGGTCTGGCCG GTGTGCTGGATGCATGCCCAAGGGTGCTGGGCATCACTGGTCCTTGTGAGGATGCTTTTAAAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGAATTGAGAAAATTACAGG AAATGGTGCCTTTGAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAGACCGGTTGCTCTGAGAGTAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAG AAACCACCTGCTTCCCAGAGTGCCAAGCCACAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAGAGGGCAAGGGCTTTGGGCAAGAAGCACTGGTGGTGTTTTAGGGACCG TCCTTCTCCCCTACCCAGGGAACTGGACCTGGCAGGGCACCGTGCTCATGTGGCTCCAAGGACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTAAAGTGTCATCTTCTGCC CTCCCTGTCCCAATAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAGCCTATTTTTGTATTCTTAATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGA GTGATTGCTTTCCTTCAGAGAACAGACACTTGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATACAGTATAAATACTCATTTGATTCTCGTAAAACGCGCATCTGGCGTGTG CAGTTGAGAAACTTGGTGGCACATGGGTGTTGGGGGAGTAGCCTGTGTTGGAGGGACACCAGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCACCTCCAGATCCTGCTGGC ATCACCTCCAGAGCCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATTCACGGTTAATTTACAACCCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCAT GGGCACTAGCTCATCTTTCAGGTGGAAAAGTACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAAAAGGCAAGAATGCCCATGTAAGGAGCCCAGCAGTCTGGACAGATCCT TCTTCCTCTGCTGTTGGATGAGAGTGAGTGAGTATGCTCTGGACCTTATCCTTGAAAGATGATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGGTTTGGGGGCAAAACCCT GAATCCAGCCAGTCGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAGCCAGGTATGTAGCCCTGTCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCT TCAGTAGAAGGCATTTGTGGGCTGCAGAGTTGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCTGTATGCAGTTGGACTCGTCAGAGATAGTAAAATCATCTTTTAGTGTT TTTTTGTTGCTGATGTCTTGTACCCATTTGTTTTTTACATGGGGTTGTAGATCGAGTTCTCAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTGATACATATGCTTTGTATATTTTGATTACTTGTTTTCGTTTTTG ACTATAAAGGAGCTTTTTTATTTTGGGAGGGGAGGAGTGTCATTTTTGAGAATCTTGGGTTCCTGAAAAAGAACGCCCTAGTTGGATGGCTTGCCAGGGCCTTGGGGTTTGGTAGTGATTGTACAACTTAAAGCTCCTTTCTCTTGGCTG AGTGACAGGTGGCTGTTCAGGTGGACCAAAGCACCTTGACACAAGGACTCCACACTGTGCTCTCTAGTAGCACAAGGAGGAAGTTGGACAGAACATTGGGTAGTGCCTTGCGGGCTCACACATGTACTAGTGGTCTCATCTCCAGCTAGC CTTGGGAGGCCGTCCCACCAGGAAATCTCTCTATTCCGTAGCCTGAGATGTGCCCTTGTGGGTTTTATCCTGCTCAGTCAGTGGCCTAGGGGCAGGTCCTGTGTTCTCTCCCTCTCTCTCCTGGCTCTGGGACATCTGTCCCTGGCTGCC TTTCATGGAGGAAGGACACTGGCCTTTCTGGTTGGATGCTGTGTGGATGCTCTCTGCTTGAGCCTCGTGGTCTCTTGTCTCTTTTTGGACCAATATCCTCAGATTGGTGCAGCTTTTTCAGTTCAGATATCACACCCCAAGTGGATAAAG GCAACTTGCAGGAGAGGAGAGCCAGCCAAGAAGAAAATTTTAAAACCAAACCTCGTTTAGGATTTTCCTAAAGTCATCTTCTCTTTTTTCTTGCTCAGAGTTTACCTGGGAGATTTCACCAGTTTGACTCACCATTTGCAGATGTGCTTT TGTATTAAATTTAAATTTTCACATATCACATCCATTCTCAAGGTAGTTATATGCTGGAGAAGAAAAATCCTCTAGACACATGAAGGCCCACATAGTCAAGTCTTCCAGGGCAAAGCCAGCAGCCCACCCAGGTCAGGTAGCCAGCAGGGC TCAGTTCCCCTCACTCCAGACACGGACCCTCCTCTTCAGGGTCTCTTGACCCAGCTTCCTTCTCTCCTTTTACCTGAGAGCACAGACCTCTCTCAGCCAGCCTGCCCAGACCACGGGGGGCTACTCCCATGTAGTTTGGGGAGCACTTGA TCTCAGAAAAGCTCCATTGTCTGAGCAAATGGGCAGTTGTGGAGCTCAAGCCTTTCTCCTGTGCTCAAGTCCCTTCCCCAAGCAAGGCTTCAACCTCATCTACCCACCATGTAGTTTTCTCTGGCCATTTAAGTGGGGCGGCAGGGACAT GGTTGGGCCATGCCACACCAGGGCTGGTGAGGCAACCAGTTTTGATTTTGACAGAGTGGCTGGAGGAAAAGTGGCAATCAAGGTGCTGCTTGGTTTGCTCTGAGTGCAAATGGAACCAACAGGTTTCTGCTGCAATCTGTGTGTTCCCAG TGCCAGGTCACACCAGGAGGGGTGGGGCAGGGCTAACCAAGTGGTCTCTGAACTCACCGAGCGTCTGCACTTGGTTGTGAAGTTAATGGGAGTACAGAGAGCGTCTGGCCTTGGAGAGGGGTTGAGAGCCTCCTTTTTGGTTCTTCATTC CTGAGCTCTTGCCTGCCCACAAATCTGACCTCTTTGAATGGGGACGCAGTCCTTCAACAGAGAAGTTTCTATGGCAAAGAAGTTTCTATTTAGCTCTAGATCCAGCAGAGTCATCCATTCTAACTGCCCTGAAGTCTAGAGCAGGGGAGG GAACCCAGAGGCTGGGGATGAGACTAGGCAGACCCTGGTTACCATATGGACAAGGACAGGGGAAAGCACCCCCTTCCTCAATTTCTGAAAGTTCTATCTTTGGGTTCGCAGGACTTTGAGGATGATAAAGAACATATAGGTACTAGCTTG TTGTTGCTGGTCCAAAGCTTCCACAGCCCTGAGAATTTGGCTTTCGTGGCTGCTCTGGCAGCTGAGCGAAGGGAGGAAGGCAGCCGCTCTGGTGGGGACTCTAGGCACCTTCCCTGCTGTCCACTTGGATAGGCGGTGAGCCCCAGGGTA CTGAGAGGAGCCTGAGCATTTACCTGCCATTAGTGCCTCTTCCTTCAGGAGACTGGCTTGAAACGTGTGTTCATGTGCGCGTGCACACACACACATGAGCACCTGTATGTGTTAATGAATAGTTTTTCTTGGTTAATGCTTTTTAACTTC TGTTCCTTTCCGTAAGTGGATGATTCAAAATTAACGTGACTTGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGGAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGATCGGCATGGTGAAAC CCCGTTTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTG GGCGACAGAGCGAAACTCCGTCTCAAAAAAAAAAAAAAAACTTAATGTGACTGGAGTTAAAAGTGAAATGTCAGGTTGTTTAGTCACTGAATAGAGAGCTACAAGTGCTTGGTCTTTCCCAAGAATCAAACCTGAGTAGAAATACATTTA AAAGAAAAATCTACATGGTACCTATGAATCCTGTAATTTGTTTAGGGAGATCTTGTCACTCATCCCTGGTTCCTGCCCATACTGTTTGGTCTCGTTCTTGCAGTTTGCTTGGAACAGGGCCAGAGCCCCACATGAGATTGTCAGCAGGAG TGAGGAGCGCCAGTCCCTACTCCTCAGCAGGGACCCAGCACAGCAATCCGGTTGTTCTCGGTTAGACTGGGTCGGGGCCAGGGGAGAAGCAGTCACCCCTGTGTAGAGGGTTCCCGCTGTGCTTCTGAGCAGTTGCTTTGTTCAGAAGTG TTAGGAGGGTCAGATTGTGCCATAATTGTTATTAAAGAGAAAACACGCCCACCTTCCTTTCTCCCCTGCTGGCCATTGTTCATTGAGTTTTACTGAGGGCAGCCTTTGTGGAAGTCAGGGAGGTTGCCAAAGGCCTGTAGATGCCTCCTG ACAAGGTCTTGATTCCTGGTTTTCTAGCACCCATTTGCATTTTGGTCTTCAGCACAAAGCCTTGTTCCCTGTGGCCGGACTTCTGGGCAATAAGACTGGGGAGTGACTGTTGAGCAGTCTGCTGTCAGGAGAGATGGCTGAAAAGGTGAT CATCTTGGTGCTAAACAAGTAAGAGGCAACTGCCCTGTTTTTGTTTGTTTTGAGGCACAATGAAACTTTAGCCAAACTCTGCAAGAGGGTCCCATCTCCTGCCATGGCCAGGTGTGAGAGACCAAACCGAGAAAACAGCATACTCTATCA CTTAAGCCTTGGGTAGAATGGGAATTCTTTACCCTGGGTAAACGTTTTAACAAAAAAATGGAACTTAACTTCGGTTTGGACTGTGGTCGTGCTGAGGCAGGAGTGGGGTTGCCCTCTTGGGGCTGAATCTCCAGGCCTCACGAGGTCCCC TGTGGGGATGCTGCTATTTCTAAGATGCAAATTGCACATTTCCTAGATTTTGTATCTGTGGATTTGGATAAGGGAGGGGAACACGGACAAATTGCTTGTACAATTTGAAATGGGCCTCAATGGTACTTCAAACCTTTTGATTATTCCTAA ATAAAAACATAAATATATTTCACA >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841 length=1206nt Breakpoint=920nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGG GAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATA GTTCAG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841 length=6839nt Breakpoint=757nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCAT AGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGCATTGTCAGTTACGTCATCTCTAAAAATGAC CTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGCAGGGAAGTTATAGGCACAAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTG CTGCATTAAGTGATGACCGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTCAAAAAATGGACTGGCAATGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTAC CGTAATTCTGCTTTTTCATGGGAGTTTGAATCATGGACCATAACTTTTCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTTTTTAATCTAGACATGTTTGGAGTGAGAGAA AGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGCTTTGACCACTGCGGTTTTCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGT AAGGGTGAAGGCTGGAGGGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCTGGCAGAACACCCAGAGTGCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGC ATGCCCAAGGGTGCTGGGCATCACTGGTCCTTGTGAGGATGCTTTTAAAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGAATTGAGAAAATTACAGGAAATGGTGCCTTT GAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAGACCGGTTGCTCTGAGAGTAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTT CCCAGAGTGCCAAGCCACAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAGAGGGCAAGGGCTTTGGGCAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTA CCCAGGGAACTGGACCTGGCAGGGCACCGTGCTCATGTGGCTCCAAGGACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTAAAGTGTCATCTTCTGCCCTCCCTGTCCCAA TAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAGCCTATTTTTGTATTCTTAATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCC TTCAGAGAACAGACACTTGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATACAGTATAAATACTCATTTGATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACT TGGTGGCACATGGGTGTTGGGGGAGTAGCCTGTGTTGGAGGGACACCAGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCACCTCCAGATCCTGCTGGCATCACCTCCAGAG CCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATTCACGGTTAATTTACAACCCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCA TCTTTCAGGTGGAAAAGTACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAAAAGGCAAGAATGCCCATGTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTG TTGGATGAGAGTGAGTGAGTATGCTCTGGACCTTATCCTTGAAAGATGATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGGTTTGGGGGCAAAACCCTGAATCCAGCCAGT CGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAGCCAGGTATGTAGCCCTGTCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCA TTTGTGGGCTGCAGAGTTGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCTGTATGCAGTTGGACTCGTCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGA TGTCTTGTACCCATTTGTTTTTTACATGGGGTTGTAGATCGAGTTCTCAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTGATACATATGCTTTGTATATTTTGATTACTTGTTTTCGTTTTTGACTATAAAGGAGC TTTTTTTCTTGCTCAGAGTTTACCTGGGAGATTTCACCAGTTTGACTCACCATTTGCAGATGTGCTTTTGTATTAAATTTAAATTTTCACATATCACATCCATTCTCAAGGTAGTTATATGCTGGAGAAGAAAAATCCTCTAGACACATG AAGGCCCACATAGTCAAGTCTTCCAGGGCAAAGCCAGCAGCCCACCCAGGTCAGGTAGCCAGCAGGGCTCAGTTCCCCTCACTCCAGACACGGACCCTCCTCTTCAGGGTCTCTTGACCCAGCTTCCTTCTCTCCTTTTACCTGAGAGCA CAGACCTCTCTCAGCCAGCCTGCCCAGACCACGGGGGGCTACTCCCATGTAGTTTGGGGAGCACTTGATCTCAGAAAAGCTCCATTGTCTGAGCAAATGGGCAGTTGTGGAGCTCAAGCCTTTCTCCTGTGCTCAAGTCCCTTCCCCAAG CAAGGCTTCAACCTCATCTACCCACCATGTAGTTTTCTCTGGCCATTTAAGTGGGGCGGCAGGGACATGGTTGGGCCATGCCACACCAGGGCTGGTGAGGCAACCAGTTTTGATTTTGACAGAGTGGCTGGAGGAAAAGTGGCAATCAAG GTGCTGCTTGGTTTGCTCTGAGTGCAAATGGAACCAACAGGTTTCTGCTGCAATCTGTGTGTTCCCAGTGCCAGGTCACACCAGGAGGGGTGGGGCAGGGCTAACCAAGTGGTCTCTGAACTCACCGAGCGTCTGCACTTGGTTGTGAAG TTAATGGGAGTACAGAGAGCGTCTGGCCTTGGAGAGGGGTTGAGAGCCTCCTTTTTGGTTCTTCATTCCTGAGCTCTTGCCTGCCCACAAATCTGACCTCTTTGAATGGGGACGCAGTCCTTCAACAGAGAAGTTTCTATGGCAAAGAAG TTTCTATTTAGCTCTAGATCCAGCAGAGTCATCCATTCTAACTGCCCTGAAGTCTAGAGCAGGGGAGGGAACCCAGAGGCTGGGGATGAGACTAGGCAGACCCTGGTTACCATATGGACAAGGACAGGGGAAAGCACCCCCTTCCTCAAT TTCTGAAAGTTCTATCTTTGGGTTCGCAGGACTTTGAGGATGATAAAGAACATATAGGTACTAGCTTGTTGTTGCTGGTCCAAAGCTTCCACAGCCCTGAGAATTTGGCTTTCGTGGCTGCTCTGGCAGCTGAGCGAAGGGAGGAAGGCA GCCGCTCTGGTGGGGACTCTAGGCACCTTCCCTGCTGTCCACTTGGATAGGCGGTGAGCCCCAGGGTACTGAGAGGAGCCTGAGCATTTACCTGCCATTAGTGCCTCTTCCTTCAGGAGACTGGCTTGAAACGTGTGTTCATGTGCGCGT GCACACACACACATGAGCACCTGTATGTGTTAATGAATAGTTTTTCTTGGTTAATGCTTTTTAACTTCTGTTCCTTTCCGTAAGTGGATGATTCAAAATTAACGTGACTTGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTTT GGGAGGCCAAGGGAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGATCGGCATGGTGAAACCCCGTTTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGAAG GAGAATCACTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCGTCTCAAAAAAAAAAAAAAAACTTAATGTGACTGGAGTTAAAAGTGAAATGTCAGGTTGTTTA GTCACTGAATAGAGAGCTACAAGTGCTTGGTCTTTCCCAAGAATCAAACCTGAGTAGAAATACATTTAAAAGAAAAATCTACATGGTACCTATGAATCCTGTAATTTGTTTAGGGAGATCTTGTCACTCATCCCTGGTTCCTGCCCATAC TGTTTGGTCTCGTTCTTGCAGTTTGCTTGGAACAGGGCCAGAGCCCCACATGAGATTGTCAGCAGGAGTGAGGAGCGCCAGTCCCTACTCCTCAGCAGGGACCCAGCACAGCAATCCGGTTGTTCTCGGTTAGACTGGGTCGGGGCCAGG GGAGAAGCAGTCACCCCTGTGTAGAGGGTTCCCGCTGTGCTTCTGAGCAGTTGCTTTGTTCAGAAGTGTTAGGAGGGTCAGATTGTGCCATAATTGTTATTAAAGAGAAAACACGCCCACCTTCCTTTCTCCCCTGCTGGCCATTGTTCA TTGAGTTTTACTGAGGGCAGCCTTTGTGGAAGTCAGGGAGGTTGCCAAAGGCCTGTAGATGCCTCCTGACAAGGTCTTGATTCCTGGTTTTCTAGCACCCATTTGCATTTTGGTCTTCAGCACAAAGCCTTGTTCCCTGTGGCCGGACTT CTGGGCAATAAGACTGGGGAGTGACTGTTGAGCAGTCTGCTGTCAGGAGAGATGGCTGAAAAGGTGATCATCTTGGTGCTAAACAAGTAAGAGGCAACTGCCCTGTTTTTGTTTGTTTTGAGGCACAATGAAACTTTAGCCAAACTCTGC AAGAGGGTCCCATCTCCTGCCATGGCCAGGTGTGAGAGACCAAACCGAGAAAACAGCATACTCTATCACTTAAGCCTTGGGTAGAATGGGAATTCTTTACCCTGGGTAAACGTTTTAACAAAAAAATGGAACTTAACTTCGGTTTGGACT GTGGTCGTGCTGAGGCAGGAGTGGGGTTGCCCTCTTGGGGCTGAATCTCCAGGCCTCACGAGGTCCCCTGTGGGGATGCTGCTATTTCTAAGATGCAAATTGCACATTTCCTAGATTTTGTATCTGTGGATTTGGATAAGGGAGGGGAAC ACGGACAAATTGCTTGTACAATTTGAAATGGGCCTCAATGGTACTTCAAACCTTTTGATTATTCCTAAATAAAAACATAAATATATTTC >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841 length=1295nt Breakpoint=920nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGG GAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATA GTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACA >CTSZ_ZHX3_ENST00000217131_ENST00000557816_57572657_39813841 length=1138nt Breakpoint=757nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCAT AGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCA >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841 length=1301nt Breakpoint=920nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATGCCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGG GAGAGCTTCCAGAATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATA GTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCA >CTSZ_ZHX3_ENST00000217131_ENST00000559234_57572657_39813841 length=3844nt Breakpoint=757nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCAT AGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGCATTGTCAGTTACGTCATCTCTAAAAATGAC CTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGCAGGGAAGTTATAGGCACAAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTG CTGCATTAAGTGATGACCGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTCAAAAAATGGACTGGCAATGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTAC CGTAATTCTGCTTTTTCATGGGAGTTTGAATCATGGACCATAACTTTTCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTTTTTAATCTAGACATGTTTGGAGTGAGAGAA AGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGCTTTGACCACTGCGGTTTTCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGT AAGGGTGAAGGCTGGAGGGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCTGGCAGAACACCCAGAGTGCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGC ATGCCCAAGGGTGCTGGGCATCACTGGTCCTTGTGAGGATGCTTTTAAAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGAATTGAGAAAATTACAGGAAATGGTGCCTTT GAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAGACCGGTTGCTCTGAGAGTAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTT CCCAGAGTGCCAAGCCACAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAGAGGGCAAGGGCTTTGGGCAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTA CCCAGGGAACTGGACCTGGCAGGGCACCGTGCTCATGTGGCTCCAAGGACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTAAAGTGTCATCTTCTGCCCTCCCTGTCCCAA TAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAGCCTATTTTTGTATTCTTAATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCC TTCAGAGAACAGACACTTGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATACAGTATAAATACTCATTTGATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACT TGGTGGCACATGGGTGTTGGGGGAGTAGCCTGTGTTGGAGGGACACCAGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCACCTCCAGATCCTGCTGGCATCACCTCCAGAG CCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATTCACGGTTAATTTACAACCCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCA TCTTTCAGGTGGAAAAGTACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAAAAGGCAAGAATGCCCATGTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTG TTGGATGAGAGTGAGTGAGTATGCTCTGGACCTTATCCTTGAAAGATGATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGGTTTGGGGGCAAAACCCTGAATCCAGCCAGT CGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAGCCAGGTATGTAGCCCTGTCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCA TTTGTGGGCTGCAGAGTTGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCTGTATGCAGTTGGACTCGTCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGA TGTCTTGTACCCATTTGTTTTTTACATGGGGTTGTAGATCGAGTTCTCAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTG >CTSZ_ZHX3_ENST00000217131_ENST00000560361_57572657_39813841 length=1132nt Breakpoint=757nt GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCGGAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGC TTCTGCTGCTCGTGCTGCTGGCGGGCGCGGCGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACCCCCGGCCTCATGAGTACCTGTCCCCAGCGG ATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCCGGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGTGGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGG ACCAGGAGTGTGACAAGTTTAACCAATGTGGGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGAAGATGATGGCAGAAATCTATGCAAATGGTC CCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCAT AGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
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Fusion Protein Sequence for CTSZ_ZHX3 |
| In-frame Fusion Protein Sequences. |
>CTSZ_ZHX3_ENST00000217131_ENST00000309060_57571693_39813841 length=267nt MEGGLRPRWPRARYPVGRWSVCWVRAAGFALAMAPWLQLLSLLGLLPGAVAAPAQPRAASFQAWGPPSPELLAPTRFALEMFNRGRAAGTRAVLGLVRGRVRRMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGS LRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841 length=375nt MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841 length=375nt MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841 length=375nt MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000557816_57572657_39813841 length=236nt MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMSTCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPP PSCPCRTSSTAVTLAPVKGVMTCPCGTTPTSTASLTRPATTTRPRTRSVTSLTNVGHAMNSKSATPSGTTPSGGWETTAPSLGGRR >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841 length=375nt MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000559234_57572657_39813841 length=236nt MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMSTCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPP PSCPCRTSSTAVTLAPVKGVMTCPCGTTPTSTASLTRPATTTRPRTRSVTSLTNVGHAMNSKSATPSGTTPSGGWETTAPSLGGRR >CTSZ_ZHX3_ENST00000217131_ENST00000560361_57572657_39813841 length=236nt MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMSTCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPP PSCPCRTSSTAVTLAPVKGVMTCPCGTTPTSTASLTRPATTTRPRTRSVTSLTNVGHAMNSKSATPSGTTPSGGWETTAPSLGGRR |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for CTSZ_ZHX3 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.Q121L_375_Q138L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVLNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.G227R_375_G244R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTRGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.C132F_375_C149F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSFE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.G127R_375_G144R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCRNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.V140M_375_V157M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSMWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A96T_375_A113T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHTSTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.E152D_375_E169D length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDDTCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.G130V_375_G147V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAVSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A218T_375_A235T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMTTERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.D235N_375_D252N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQNTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.R104W_375_R121W length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADWINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.D125G_375_D142G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIGCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.N240H_375_N257H length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIHHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.W68R_375_W85R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDRRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.R109M_375_R126M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKMKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.H95N_375_H112N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWANASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.N75S;p.V123I_375_N92S;V140I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVSYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNIIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.S244F_375_S261F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVFVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.S139P_375_S156P length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLPVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.V243I_375_V260I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVISVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A129V_375_A146V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNVGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A223G_375_A240G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLGNYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.W248L_375_W265L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGLGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000432768_57571693_39813841_5-gene_p.E255K_375_E272K length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTKYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.Q121L_375_Q138L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVLNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.G227R_375_G244R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTRGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.C132F_375_C149F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSFE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.G127R_375_G144R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCRNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.V140M_375_V157M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSMWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A96T_375_A113T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHTSTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.E152D_375_E169D length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDDTCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.G130V_375_G147V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAVSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A218T_375_A235T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMTTERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.D235N_375_D252N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQNTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.R104W_375_R121W length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADWINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.D125G_375_D142G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIGCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.N240H_375_N257H length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIHHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.W68R_375_W85R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDRRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.R109M_375_R126M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKMKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.H95N_375_H112N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWANASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.N75S;p.V123I_375_N92S;V140I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVSYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNIIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.S244F_375_S261F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVFVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.S139P_375_S156P length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLPVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.V243I_375_V260I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVISVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A129V_375_A146V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNVGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A223G_375_A240G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLGNYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.W248L_375_W265L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGLGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000540170_57572657_39813841_5-gene_p.E255K_375_E272K length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTKYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.Q121L_375_Q138L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVLNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.G227R_375_G244R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTRGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.C132F_375_C149F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSFE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.G127R_375_G144R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCRNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.V140M_375_V157M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSMWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A96T_375_A113T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHTSTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.E152D_375_E169D length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDDTCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.G130V_375_G147V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAVSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A218T_375_A235T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMTTERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.D235N_375_D252N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQNTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.R104W_375_R121W length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADWINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.D125G_375_D142G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIGCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.N240H_375_N257H length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIHHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.W68R_375_W85R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDRRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.R109M_375_R126M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKMKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.H95N_375_H112N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWANASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.N75S;p.V123I_375_N92S;V140I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVSYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNIIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.S244F_375_S261F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVFVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.S139P_375_S156P length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLPVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.V243I_375_V260I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVISVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A129V_375_A146V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNVGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A223G_375_A240G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLGNYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.W248L_375_W265L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGLGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000544979_57571693_39813841_5-gene_p.E255K_375_E272K length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTKYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.Q121L_375_Q138L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVLNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.G227R_375_G244R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTRGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.C132F_375_C149F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSFE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.G127R_375_G144R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCRNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.V140M_375_V157M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSMWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A96T_375_A113T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHTSTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.E152D_375_E169D length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDDTCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.G130V_375_G147V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAVSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A218T_375_A235T length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMTTERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.D235N_375_D252N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQNTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.R104W_375_R121W length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADWINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.D125G_375_D142G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIGCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.S262L_375_S279L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNLWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.N240H_375_N257H length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIHHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.W68R_375_W85R length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDRRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.R109M_375_R126M length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKMKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.H95N_375_H112N length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWANASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.N75S;p.V123I_375_N92S;V140I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVSYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNIIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.S244F_375_S261F length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVFVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.S139P_375_S156P length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLPVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.V243I_375_V260I length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVISVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.G194S_375_G211S length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYSSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A129V_375_A146V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNVGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A223G_375_A240G length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLGNYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.W248L_375_W265L length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGLGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.A112V_375_A129V length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGVWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG >CTSZ_ZHX3_ENST00000217131_ENST00000558993_57571693_39813841_5-gene_p.E255K_375_E272K length=375AA MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCE GGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTKYWIVRNSWGEPWKQTEFDLINVKDWPVW ETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQFFLPQCRTFPLPSNG |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-05-4384-01A | 5-gene | p.Q121L | 375 | Q138L |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-24-2033-01A | 5-gene | p.G227R | 375 | G244R |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-55-7283-01A | 5-gene | p.C132F | 375 | C149F |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-55-8614-01A | 5-gene | p.G127R | 375 | G144R |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-5M-AAT6-01A | 5-gene | p.V140M | 375 | V157M |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-66-2770-01A | 5-gene | p.A96T | 375 | A113T |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-77-8146-01A | 5-gene | p.E152D | 375 | E169D |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-93-8067-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-A5-A0G2-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-AA-3715-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-AB-2811-03B | 5-gene | p.G130V | 375 | G147V |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-AP-A059-01A | 5-gene | p.A218T | 375 | A235T |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-AX-A06F-01A | 5-gene | p.D235N | 375 | D252N |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-AX-A2HD-01A | 5-gene | p.R104W | 375 | R121W |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-B7-A5TI-01A | 5-gene | p.D125G | 375 | D142G |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-C5-A1MP-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-CA-6717-01A | 5-gene | p.N240H | 375 | N257H |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-D1-A16E-01A | 5-gene | p.W68R | 375 | W85R |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-D3-A3CE-06A | 5-gene | p.R109M | 375 | R126M |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-EO-A22R-01A | 5-gene | p.H95N | 375 | H112N |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-EO-A22U-01A | 5-gene | p.N75S;p.V123I | 375 | N92S;V140I |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-EW-A1J5-01A | 5-gene | p.S244F | 375 | S261F |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-EY-A215-01A | 5-gene | p.S139P | 375 | S156P |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-F4-6856-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-FP-8099-01A | 5-gene | p.V243I | 375 | V260I |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-G4-6628-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-HT-7467-01A | 5-gene | p.A129V | 375 | A146V |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-IR-A3LH-01A | 5-gene | p.A223G | 375 | A240G |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-QN-A5NN-01A | 5-gene | p.W248L | 375 | W265L |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-SL-A6JA-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000432768_57571693_39813841 | TCGA-UY-A9PB-01A | 5-gene | p.E255K | 375 | E272K |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-05-4384-01A | 5-gene | p.Q121L | 375 | Q138L |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-24-2033-01A | 5-gene | p.G227R | 375 | G244R |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-55-7283-01A | 5-gene | p.C132F | 375 | C149F |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-55-8614-01A | 5-gene | p.G127R | 375 | G144R |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-5M-AAT6-01A | 5-gene | p.V140M | 375 | V157M |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-66-2770-01A | 5-gene | p.A96T | 375 | A113T |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-77-8146-01A | 5-gene | p.E152D | 375 | E169D |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-93-8067-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-A5-A0G2-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-AA-3715-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-AB-2811-03B | 5-gene | p.G130V | 375 | G147V |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-AP-A059-01A | 5-gene | p.A218T | 375 | A235T |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-AX-A06F-01A | 5-gene | p.D235N | 375 | D252N |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-AX-A2HD-01A | 5-gene | p.R104W | 375 | R121W |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-B7-A5TI-01A | 5-gene | p.D125G | 375 | D142G |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-C5-A1MP-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-CA-6717-01A | 5-gene | p.N240H | 375 | N257H |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-D1-A16E-01A | 5-gene | p.W68R | 375 | W85R |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-D3-A3CE-06A | 5-gene | p.R109M | 375 | R126M |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-EO-A22R-01A | 5-gene | p.H95N | 375 | H112N |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-EO-A22U-01A | 5-gene | p.N75S;p.V123I | 375 | N92S;V140I |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-EW-A1J5-01A | 5-gene | p.S244F | 375 | S261F |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-EY-A215-01A | 5-gene | p.S139P | 375 | S156P |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-F4-6856-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-FP-8099-01A | 5-gene | p.V243I | 375 | V260I |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-G4-6628-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-HT-7467-01A | 5-gene | p.A129V | 375 | A146V |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-IR-A3LH-01A | 5-gene | p.A223G | 375 | A240G |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-QN-A5NN-01A | 5-gene | p.W248L | 375 | W265L |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-SL-A6JA-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000540170_57572657_39813841 | TCGA-UY-A9PB-01A | 5-gene | p.E255K | 375 | E272K |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-05-4384-01A | 5-gene | p.Q121L | 375 | Q138L |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-24-2033-01A | 5-gene | p.G227R | 375 | G244R |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-55-7283-01A | 5-gene | p.C132F | 375 | C149F |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-55-8614-01A | 5-gene | p.G127R | 375 | G144R |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-5M-AAT6-01A | 5-gene | p.V140M | 375 | V157M |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-66-2770-01A | 5-gene | p.A96T | 375 | A113T |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-77-8146-01A | 5-gene | p.E152D | 375 | E169D |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-93-8067-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-A5-A0G2-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-AA-3715-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-AB-2811-03B | 5-gene | p.G130V | 375 | G147V |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-AP-A059-01A | 5-gene | p.A218T | 375 | A235T |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-AX-A06F-01A | 5-gene | p.D235N | 375 | D252N |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-AX-A2HD-01A | 5-gene | p.R104W | 375 | R121W |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-B7-A5TI-01A | 5-gene | p.D125G | 375 | D142G |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-C5-A1MP-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-CA-6717-01A | 5-gene | p.N240H | 375 | N257H |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-D1-A16E-01A | 5-gene | p.W68R | 375 | W85R |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-D3-A3CE-06A | 5-gene | p.R109M | 375 | R126M |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-EO-A22R-01A | 5-gene | p.H95N | 375 | H112N |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-EO-A22U-01A | 5-gene | p.N75S;p.V123I | 375 | N92S;V140I |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-EW-A1J5-01A | 5-gene | p.S244F | 375 | S261F |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-EY-A215-01A | 5-gene | p.S139P | 375 | S156P |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-F4-6856-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-FP-8099-01A | 5-gene | p.V243I | 375 | V260I |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-G4-6628-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-HT-7467-01A | 5-gene | p.A129V | 375 | A146V |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-IR-A3LH-01A | 5-gene | p.A223G | 375 | A240G |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-QN-A5NN-01A | 5-gene | p.W248L | 375 | W265L |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-SL-A6JA-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000544979_57571693_39813841 | TCGA-UY-A9PB-01A | 5-gene | p.E255K | 375 | E272K |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-05-4384-01A | 5-gene | p.Q121L | 375 | Q138L |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-24-2033-01A | 5-gene | p.G227R | 375 | G244R |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-55-7283-01A | 5-gene | p.C132F | 375 | C149F |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-55-8614-01A | 5-gene | p.G127R | 375 | G144R |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-5M-AAT6-01A | 5-gene | p.V140M | 375 | V157M |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-66-2770-01A | 5-gene | p.A96T | 375 | A113T |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-77-8146-01A | 5-gene | p.E152D | 375 | E169D |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-93-8067-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-A5-A0G2-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-AA-3715-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-AB-2811-03B | 5-gene | p.G130V | 375 | G147V |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-AP-A059-01A | 5-gene | p.A218T | 375 | A235T |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-AX-A06F-01A | 5-gene | p.D235N | 375 | D252N |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-AX-A2HD-01A | 5-gene | p.R104W | 375 | R121W |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-B7-A5TI-01A | 5-gene | p.D125G | 375 | D142G |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-C5-A1MP-01A | 5-gene | p.S262L | 375 | S279L |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-CA-6717-01A | 5-gene | p.N240H | 375 | N257H |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-D1-A16E-01A | 5-gene | p.W68R | 375 | W85R |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-D3-A3CE-06A | 5-gene | p.R109M | 375 | R126M |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-EO-A22R-01A | 5-gene | p.H95N | 375 | H112N |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-EO-A22U-01A | 5-gene | p.N75S;p.V123I | 375 | N92S;V140I |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-EW-A1J5-01A | 5-gene | p.S244F | 375 | S261F |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-EY-A215-01A | 5-gene | p.S139P | 375 | S156P |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-F4-6856-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-FP-8099-01A | 5-gene | p.V243I | 375 | V260I |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-G4-6628-01A | 5-gene | p.G194S | 375 | G211S |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-HT-7467-01A | 5-gene | p.A129V | 375 | A146V |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-IR-A3LH-01A | 5-gene | p.A223G | 375 | A240G |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-QN-A5NN-01A | 5-gene | p.W248L | 375 | W265L |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-SL-A6JA-01A | 5-gene | p.A112V | 375 | A129V |
| ENST00000217131_ENST00000558993_57571693_39813841 | TCGA-UY-A9PB-01A | 5-gene | p.E255K | 375 | E272K |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
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Fusion Gene Exprssed Samples for CTSZ_ZHX3 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | BRCA | TCGA-BH-A0GY-01A | CTSZ | chr20 | 57571693 | - | ZHX3 | chr20 | 39813841 | - | |
| ChimerDB | BRCA | TCGA-BH-A0GY-01A | CTSZ | chr20 | 57572657 | - | ZHX3 | chr20 | 39813841 | - | |
| WashU | BRCA | TCGA-BH-A0GY-01A | CTSZ | chr20 | 57571694 | - | ZHX3 | chr20 | 39813841 | - | |
| cBioPortal | BRCA_TCGA_PAN_CAN_ATLAS_2018 | BRCA | TCGA-BH-A0GY-01 | CTSZ | chr20 | 58996639 | ZHX3 | chr20 | 41185201 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
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Related Drugs for CTSZ_ZHX3 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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