|
||||||
|
Fusion gene:ESR1_ASPH (FusionGDB2 ID:HG2099TG444) |
Fusion Gene Summary for ESR1_ASPH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ESR1_ASPH | Fusion gene ID: hg2099tg444 | Hgene | Tgene | Gene symbol | ESR1 | ASPH | Gene ID | 2099 | 444 |
| Gene name | estrogen receptor 1 | aspartate beta-hydroxylase | |
| Synonyms | ER|ESR|ESRA|ESTRR|Era|NR3A1 | AAH|BAH|CASQ2BP1|FDLAB|HAAH|JCTN|junctin | |
| Cytomap | 6q25.1-q25.2 | 8q12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | estrogen receptorE2 receptor alphaER-alphaestradiol receptorestrogen nuclear receptor alphaestrogen receptor alpha E1-E2-1-2estrogen receptor alpha E1-N2-E2-1-2nuclear receptor subfamily 3 group A member 1oestrogen receptor alpha | aspartyl/asparaginyl beta-hydroxylaseA beta H-J-JASP beta-hydroxylasecardiac junctinhumbugjunctatepeptide-aspartate beta-dioxygenase | |
| Modification date | 20240411 | 20240411 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000206249, ENST00000338799, ENST00000427531, ENST00000440973, ENST00000443427, ENST00000456483, ENST00000406599, ENST00000482101, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 29 X 45 X 17=22185 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 11 X 22 X 10=2420 |
| # samples | 98 | 31 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(98/22185*10)=-4.50065899370502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(31/2420*10)=-2.96466692688772 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ESR1 [Title/Abstract] AND ASPH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ESR1(152201906)-ASPH(62416068), # samples:2 | ||
| ESR1-ASPH in-frame fusion transcripts reconstructed from RNA-seq breakpoints * For each RNA-seq based exon-junction breakpoint, we joined the Ensembl transcripts (ENST) whose exon boundaries match the breakpoint on each side: the 5'-gene ENST from its transcription start to the 5'-breakpoint and the 3'-gene ENST from the 3'-breakpoint to its transcription end, keeping only in-frame combinations. Each row is one fusion transcript: the ESR1 part (blue) joined at the breakpoint (red line) to the ASPH part (orange), both drawn 5' to 3'. GENCODE v19 transcripts of each gene are shown below in dark gray. View in the UCSC Genome Browser: ESR1 part, ASPH part |
 |
Top |
Fusion Gene Breakpoints for ESR1_ASPH |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416067 |
| ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 |
| ESR1 | chr6 | 151880771 | ASPH | chr8 | 61503509 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
Top |
Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for ESR1_ASPH |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ESR1 | GO:0010629 | negative regulation of gene expression | 21695196 |
| Hgene | ESR1 | GO:0030520 | intracellular estrogen receptor signaling pathway | 9841876 |
| Hgene | ESR1 | GO:0032355 | response to estradiol | 15304487 |
| Hgene | ESR1 | GO:0043124 | negative regulation of canonical NF-kappaB signal transduction | 7651415|16043358 |
| Hgene | ESR1 | GO:0043433 | negative regulation of DNA-binding transcription factor activity | 10816575 |
| Hgene | ESR1 | GO:0043627 | response to estrogen | 11581164 |
| Hgene | ESR1 | GO:0045893 | positive regulation of DNA-templated transcription | 20074560 |
| Hgene | ESR1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 11544182 |
| Hgene | ESR1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 9841876|11265755|12047722|15345745|15831516|18563714 |
| Hgene | ESR1 | GO:0051091 | positive regulation of DNA-binding transcription factor activity | 9328340|10681512 |
| Hgene | ESR1 | GO:0051123 | RNA polymerase II preinitiation complex assembly | 9841876 |
| Hgene | ESR1 | GO:0071392 | cellular response to estradiol stimulus | 12535528|15831516 |
| Tgene | ASPH | GO:0045862 | positive regulation of proteolysis | 18387192 |
| Tgene | ASPH | GO:0097202 | activation of cysteine-type endopeptidase activity | 18387192 |
Top |
Fusion Genomic Features for ESR1_ASPH |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | 3.01e-03 | 9.97e-01 |
| ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - | 9.99e-01 | 5.51e-04 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
 |
Top |
Fusion Gene ORF Annotations for ESR1_ASPH |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000206249 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| Frame-shift | ENST00000338799 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| Frame-shift | ENST00000427531 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| Frame-shift | ENST00000440973 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| Frame-shift | ENST00000443427 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| Frame-shift | ENST00000456483 | ENST00000379454 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000206249 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000338799 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000427531 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000440973 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000443427 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| In-frame | ENST00000456483 | ENST00000541428 | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000206249 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 4075 | 280 |
| ENST00000338799 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 5173 | 280 |
| ENST00000427531 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 3426 | 116 |
| ENST00000440973 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 4083 | 280 |
| ENST00000443427 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 3974 | 280 |
| ENST00000456483 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 3931 | 280 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000206249 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 1.33e-02 | 9.87e-01 |
| ENST00000338799 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 2.62e-02 | 9.74e-01 |
| ENST00000427531 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 8.42e-01 | 1.58e-01 |
| ENST00000440973 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 1.54e-02 | 9.85e-01 |
| ENST00000443427 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 1.40e-02 | 9.86e-01 |
| ENST00000456483 | ENST00000541428 | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | 1.66e-02 | 9.83e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
Top |
Fusion Protein Retained/Non-Retained Functional Features for ESR1_ASPH |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
 |
| - View each breakpoint in FGviewer (DNA, RNA and protein levels; GRCh37). If you use FGviewer, please cite: Kim P, Yiya K, Zhou X. FGviewer: an online visualization tool for functional features of human fusion genes. Nucleic Acids Res. 2020;48(W1):W313-W320. doi:10.1093/nar/gkaa364 |
| Data | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | FGviewer |
| RNA-seq | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416067 | View |
| RNA-seq | ESR1 | chr6 | 152201906 | ASPH | chr8 | 62416068 | View |
| RNA-seq | ESR1 | chr6 | 151880771 | ASPH | chr8 | 61503509 | View |
| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
ESR1_ASPH_chr6-152201906_chr8-62416068.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Fusion Transcript Sequence for ESR1_ASPH |
| In-frame Fusion Transcript Sequences. |
>ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068 length=4075nt Breakpoint=1122aa GAGTTGTGCCTGGAGTGATGTTTAAGCCAATGTCAGGGCAAGGCAACAGTCCCTGGCCGTCCTCCAGCACCTTTGTAATGCATATGAGCTCGGGAGACCAGTACTTAAAGTTGGAGGCCCGGGAGCCCAGGAGCTGGCGGAGGGCGTTCG TCCTGGGACTGCACTTGCTCCCGTCGGGTCGCCCGGCTTCACCGGACCCGCAGGCTCCCGGGGCAGGGCCGGGGCCAGAGCTCGCGTGTCGGCGGGACATGCGCTGCGTCGCCTCTAACCTCGGGCTGTGCTCTTTTTCCAGGTGGCCCG CCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGC AGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCT ACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCT ACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAAAGATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGAATCTGCCA AGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCATTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATTCAAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTGCACCATTG ATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTACGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCTTTCCG GCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGA ATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGG TCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTTCTATG CAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCT TCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATG CTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAAAAGTA TAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAG CCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGA CTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGATGATC AAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATAT AGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCA GTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGTAAAAA GGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTC ATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTAT TACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTCACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTACATAAGA AAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGATACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTATTTCTCC AAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATTAAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGTTGAATAAT CTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGTTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATGTCATGC AGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCTGATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAGACTAGG TAAATAAAATGACCTTTGACATTTC >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068 length=5173nt Breakpoint=2220aa CTAGAGCATGGGTGGCCATTGTTGACCTACAGGAGGCACCACTGTCACCAACAAAGGGTAACAGTCTTTCTTTTCAATATTTATTTATATCCAGTATTTATTTTCAATACTGACTATGGAGAGAGCTCTCCTGTGCTCAAACACTGCAAT ACTGGGGGTCTTTCAAAGCACAAAAACATATATTTGCATGATGGCATCATTAACATTTTTATGGCTTTCTATTTCTTTTTTGTACTGGTCTCAAGAGCCACTCATAAATCTCTCAGTAACTGCATAGTGTCCCAGGGCCAGAGACCGGCC ACTCCTGGCATTGTGATTAGAGTCATTTAATATCCAAGGTGGTGACTAATGTCTGGCAACAAAGCCTCCATTGGGTGTCATGTGTCCTGGGACCCTGAGCGTGGGCACTCTAGGAGCACCTCAGTATTGCGTGTTAGTACTATGGCCGAG AGAATAGTTGAGAAAGTGGTCAAGAGGTGGATCCATGTGAACGCCACTGGGAAATGAGAGACCTCGTTCCCAATCACGGTCAGTGCAACTCGAAAGCCTAAAATCAGTTTAAAACAAAGGTATCTACCTTTATCTTATGTTCATATCCTA GGCTTTTAATAATACGTATTTTTCACATGTTTACAGAAAGCAGTCAACTGAGCTATTCATGGAAAGGTTTGTGGGTTTGGTTAACGAAGTGGAGGAGTATTACATTTCAGCTGGAAACACATCCCTAGAATGCCAAAACATTTATTCCAA AGTCTGGTTTCCTGGTGCAATCGGAGGCATGGCAATGCCTCTGTTCAGAGACTGGGGGCTAGGGCCAGTAAGGCATTTGATCCACATGTATCCCAGAAGGCTTTTATTGTTAAATTATATTCTTTCGGAAAAACCACCCATGTCCTATTT TGTAAACTTGATATCCATACACTTTTGACTGGCATTCTATTTTAGCCGTAAGACTATGATTCACAGCAAGCCTGTTTTTCCTCTTGCTTGGGGTGGCAGCAGAAAGCATAGGGTACTTTCCAGCCTCCAAGGGTAGGGGCAAAGGGGCTG GGGTTTCTCCTCCCCAGTACAGCTTTCTCTGGCTGTGCCACACTGCTCCCTGTGAGCAGACAGCAAGTCTCCCCTCACTCCCCACTGCCATTCATCCAGCGCTGTGCAGTAGCCCAGCTGCGTGTCTGCCGGGAGGGGCTGCCAAGTGCC CTGCCTACTGGCTGCTTCCCGAATCCCTGCCATTCCACGCACAAACACATCCACACACTCTCTCTGCCTAGTTCACACACTGAGCCACTCGCACATGCGAGCACATTCCTTCCTTCCTTCTCACTCTCTCGGCCCTTGACTTCTACAAGC CCATGGAACATTTCTGGAAAGACGTTCTTGATCCAGCAGGGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCC TACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACG CCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGC CGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAAA GATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGAATCTGCCAAGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCATTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATTC AAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTGCACCATTGATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTACGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCTT TGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCT GGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCA ATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAAC ATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTA TTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTC AAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAG ATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTG GGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGG CGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACAT AGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCAC TGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTG AAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAA TTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTG GTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCA CTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTC ACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTACATAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGAT ACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTATTTCTCCAAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATT AAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGTTGAATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGT TTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATGTCATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCTG ATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAGACTAGGTAAATAAAATGACCTTTGACATTTC >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068 length=3426nt Breakpoint=473aa GCTTAAAAATAATCTCCTGCCAGCCCAGTGACAAGCCTGTCCCACCCGGGGAGAATGCCCCGGAGTGGCGTGCGGGTCAGCCAGGGTCTGCGCCTCGCAGCCACTGTGGAAGGAGCGCGGCCGGTCCAGGACACAGGAGACCACTTTGTG ACTTCAATGGCGAAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAAAGATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGAATCTGCCAAGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCA TTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATTCAAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTGCACCATTGATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTA CGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAG AGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTC AAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAG CCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCAC TACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAA AAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTT TTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTG GCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGA TTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACT GTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTG AATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTC CATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTAT TGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAG GGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAG TAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATA CTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTCACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTACATAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTT TTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGATACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTATTTCTCCAAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGG GAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATTAAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGTTGAATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTT AAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGTTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATGTCATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGA AAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCTGATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAGACTAGGTAAATAAAATGACCTTTGACATTTC >ESR1_ASPH_ENST00000440973_ENST00000541428_152201906_62416068 length=4083nt Breakpoint=1130aa ATGGTCATAACAGCCTCCTGTCTACCGACTCAGAACGGATTTTACCAAAACTGAAAATGCAGGCTCCATGCTCAGAAGCTCTTTAACAGGCTCGAAAGGTCCATGCTCCTTTCTCCTGCCCATTCTATAGCATAAGAAGACAGTCTCTGA GTGATAATCTTCTCTTCAAGAAGAAGAAAACTAGGAAGGAGTAAGCACAAAGATCTCTTCACATTCTCCGGGACTGCGGTACCAAATATCAGCACAGCACTTCTTGAAAAAGGATGTAGATTTTAATCTGAACTTTGAACCATCACTGAG GTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAA CCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGG CCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCA GGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAAAGATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGA ATCTGCCAAGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCATTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATTCAAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTG CACCATTGATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTACGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCA TCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTG AGGATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGAC AGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATT TTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTT TTAATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTC TCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGG AAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATG TCAGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGT TTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAA AGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATG GCACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATT AGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAA AGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTAT AAGTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGA AATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTCACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGT ACATAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGATACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTT ATTTCTCCAAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATTAAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGT TGAATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGTTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCA TGTCATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCTGATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGG AGACTAGGTAAATAAAATGACCTTTGACATTTC >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068 length=3974nt Breakpoint=1021aa GACAAACAGAGATATATCGGAGTCTGGCACGGGGCACATAAGGCAGCACATTAGAGAAAGCCGGCCCCTGGATCCGTCTTTCGCGTTTATTTTAAGCCCAGTCTTCCCTGGGCCACCTTTAGCAGATCCTCGTGCGCCCCCGCCCCCTGG CCGTGAAACTCAGCCTCTATCCAGCAGCGACGACAAGTAAAGTGGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCC CTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAAC GCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCCTCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCG CCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGGTGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAA AGATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGAATCTGCCAAGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCATTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATT CAAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTGCACCATTGATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTACGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCT TTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATCTTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTC TGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAGGATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGC AATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAGCACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAA CATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTTTCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCT ATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTTAATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCT CAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTCACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCA GATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAAAAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCT GGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTCAGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGG GCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTTGGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACA TAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAGATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCA CTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGCACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTT GAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAGCTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAA ATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAGTAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTT GGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAAGTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTC ACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAATGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATT CACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTACATAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGA TACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTATTTCTCCAAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAAT TAAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGTTGAATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTG TTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATGTCATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCT GATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAGACTAGGTAAATAAAATGACCTTTGACATTTC >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068 length=3931nt Breakpoint=978aa AAACACATCCACACACTCTCTCTGCCTAGTTCACACACTGAGCCACTCGCACATGCGAGCACATTCCTTCCTTCCTTCTCACTCTCTCGGCCCTTGACTTCTACAAGCCCATGGAACATTTCTGGAAAGACGTTCTTGATCCAGCAGGGT GGCCCGCCGGTTTCTGAGCCTTCTGCCCTGCGGGGACACGGTCTGCACCCTGCCCGCGGCCACGGACCATGACCATGACCCTCCACACCAAAGCATCTGGGATGGCCCTACTGCATCAGATCCAAGGGAACGAGCTGGAGCCCCTGAACC GTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCTGGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACAACTACCCCGAGGGCGCCGCCTACGAGTTCAACGCCGCGGCCGCCGCCAACGCGCAGGTCTACGGTCAGACCGGCC TCCCCTACGGCCCCGGGTCTGAGGCTGCGGCGTTCGGCTCCAACGGCCTGGGGGGTTTCCCCCCACTCAACAGCGTGTCTCCGAGCCCGCTGATGCTACTGCACCCGCCGCCGCAGCTGTCGCCTTTCCTGCAGCCCCACGGCCAGCAGG TGCCCTACTACCTGGAGAACGAGCCCAGCGGCTACACGGTGCGCGAGGCCGGCCCGCCGGCATTCTACAGGCCAAATTCAGATAATCGACGCCAGGGTGGCAGAGAAAGATTGGCCAGTACCAATGACAAGGGAAGTATGGCTATGGAAT CTGCCAAGGAGACTCGCTACTGTGCAGTGTGCAATGACTATGCTTCAGGCTACCATTATGGAGTCTGGTCCTGTGAGGGCTGCAAGGCCTTCTTCAAGAGAAGTATTCAAGGACATAACGACTATATGTGTCCAGCCACCAACCAGTGCA CCATTGATAAAAACAGGAGGAAGAGCTGCCAGGCCTGCCGGCTCCGTAAATGCTACGAAGTGGGAATGATGAAAGGTGGACCTGGGAGGAAGGCAAGGTGCTCATCTTTGATGACTCCTTTGAGCACGAGGTATGGCAGGATGCCTCATC TTTCCGGCTGATATTCATCGTGGATGTGTGGCATCCGGAACTGACACCACAGCAGAGACGCAGCCTTCCAGCAATTTAGCATGAATTCATGCAAGCTTGGGAAACTCTGGAGAGAGGCTGCCTTTCTGGTTCCATCTCCTTGGGTGTGAG GATAGAATTTCGAACACCAAGAGTCAATTCCCTTGACTTGCAGCCCGAGTAATTCAAAGCCTCCTCCTAGGGTCAGAAGACACTAAAGGGAATATTTGCCTCGCTGCAATTCATTTAGGAAACACCCTGCTGTGTGTCATCTCATGACAG CACTGGTCTTCTGCCAGTATTTAAGGTGAACATTTGATAGCTTCTACCTTACCAGCCAAAGATATTTTTTCCACATAGAATAGGTCTAATTCAATGTATAATGAGAACATATGTAGAAACTGTGAATGGATTGCTTTAGTTTGTAATTTT TCTATGCAGTTATATTTTTCTAGTGTAGCTAGACTATTTTGTCATCATGTACCACTACATTTTTGTTTATTTTAATGACAAGCTGTATAAATGCTTTACTTCTAGCTATTTAATGGTAGCATTACTGGGGAACTCAGACTTCCCTCTTTT AATTCTTCTTAGTAAAAGATACTCATGAAAAAAGCAGTTTTATTTTCCTAACAAAAAAGAAAGAGCTCATTATGTCAGTGTCTATGAACTGTACCCATCCCAACTCTCAAATCGTTTGGTTTTTTTTATCTTGATTGAGATCCTCTTCTC ACTATGCTAGTGGTGGAGATATTGACAAAATCCTATTTCTTTCAAAGAGGAACTTTTCACACCGAAAAAAGAGCATGGAATTATTTTATATTGTTATAAAAATCCCAGATGCAAATTTTTTTAATGCCAATTATTAGAGCTTCTGGGGAA AAAGTATAGTTCACGGAAATAAAACTATGTTCTTTCAGGGTTGGGTGGATAGGTGGCTGCTAGGGTGTCTGGCTCCTGGCGGCTTTGCCATCCATGAGGCAAGGGCTGGGAACACAGTGTCTTTGCCTATGGTAGATCCATGTGAATGTC AGGAAGCCAGCTCTTCAGTCTTGGAGATGATTTCTGCTACAATTCTGTAGAAAGATTAAGGATGGCAGAGTAAAAGGTTACCAAGAATGCCAGGATGTTTTTCTTGGGCGTAGGAGGTCCAGATTACTTTCCTTTTTGATGAAAGAGTTT GGAAGACTGTCCCATCTCTCTGGCTTGAGAAATCTCTGCCATTTTAAACATCACTGTGAAATAGCAATTATTATCATCTGTATTTAGTTTTAACATTACCCACAACATAGAAATAATAGGTAAAAATCGTCTTGCCTACTCATTCCAAAG ATGATCAAGTCATTAATCTAGCAAAGTATTCATGTATCAGATTTTGTATATTTTGAATCAAAGCTAACTAGGAATGTTAGATATAAGAATGTAATGATATTCATGCACTGAATTCTAAGCCAATATGAACAAAAATGCTGCATGAATGGC ACATATAGGTCACCAAAGTTCATTCACAGGTAGAAAAAACTTGTGCTTTCTTTTCCATCTAAAAACAAAAGGAGACTTTCTTTATCTCATTTAAAGAACAGCTCTTTGAAATTGAAATTGACCCTTTTTGCTTGACCTTAAGGAGATTAG CTTCCAGTAGATGAGTTTGCAAAATACTTTTCCTGTTCTTTTGTTTTGCTGGTATTGAAAACATCCCACTAAATCAGATGAAGAGGCATGGGAGGAAAAATATCCAAATTAATTACTAAAATCGAGAAGAGAAGGCAAACTCTTGAAAAG TAAAAAGGTGTTTGTGACCTTCAGTATTTATTGAACAGAGGAAATAACTGACAAGGGCAATACAATTCAATGTTCATGTAGTAACATTCATGTCACTTGTTGAATTTGGTTCTCATATGTATATTGCATACACATAAATTCAAACTATAA GTCGTCATTTTTGAGCCATCATCTTACATTCATGTAATGAAATTATGGAAGAGAGTAAAAACTAGCTCTTAACTTAGTAAATATAATATGGTATTTAAAATCAGGTCACTACAGTAAGGTTCTAAGTATTGCCAATTGAAAAGCTAGAAA TGGTATTACTGTTGCAAAGTGTTGTCAATAATTGACTCCAATAGCATTGTAAATACTTGTATCCCACAACTATTTTAAACCCAAGCAATAAAATGGATTTTCTAATTCACTTCAATTCTTTATTTCTCTTACCTATCTATGTCTTGGTAC ATAAGAAAAGTGTTTCCATCACTGCATTGGTAGAATTATTTCAGTGTTATTATTTTTGTGATTTCGTATGTCTACACAAAAATGAATTAGTTTAATTTATATTGTGATACAGTTGTTTGAGAAATATTTTTAATTCTGTTTCAACTTTAT TTCTCCAAGTGTATAATATAAAAATTACTTCTGTTATTGTTCTCTACCAATAGGGGAAAAAATTAAAACATTAGATCCATTGAGAAAGAGATGATGTAATAAATAATTAAGATTAGTAATAATATTATCAGGGGTGATTATGACCAGTTG AATAATCTCTTTCCCTTGAATTATTTAGCTAACAAATTAACTCTCCCAAATATTTAAAATAATGTAAAATCATATTTTACTGCCCATTATTAACTAAAATATTTTTGTTTGACTTTGAGCACCAACTGGTAATACTAATAAATACCCATG TCATGCAGATGGCTGGGCGAATAAGAGATGTCTAAAAATATGCACTGGTCTTGGAAAACATGGCACAAGTAAGGATATCATATATGATGTCTGTTTATTTTATGTCTGATTTCTTTTGAATGAGTAGTTGGGGACTCCATTTCTAAGGAG ACTAGGTAAATAAAATGACCTTTGACATTTC |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
Top |
Fusion Protein Sequence for ESR1_ASPH |
| In-frame Fusion Protein Sequences. |
>ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068 length=280aa MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068 length=280aa MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068 length=116aa MASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000440973_ENST00000541428_152201906_62416068 length=280aa MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068 length=280aa MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068 length=280aa MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
Top |
Personalized Fusion Protein Sequence for ESR1_ASPH |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.T224N_280_T224N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPANNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A166S_280_A166S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLSSTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.G40V_280_G40V length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLVEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247D_280_E247D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYDVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.P82H_280_P82H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGHGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.K171M_280_K171M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDMGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R142P_280_R142P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVPEAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E41D_280_E41D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGDVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.Q17H_280_Q17H length=280AA MTMTLHTKASGMALLHHIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.H196R_280_H196R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYRYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A239S_280_A239S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQSCRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.N69K_280_N69K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAAKAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.C188R_280_C188R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVRNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R259Q_280_A259Q length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKQRCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.Y52H_280_Y52H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVHNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A9T;p.E247K_280_A9T;E247K length=280AA MTMTLHTKTSGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247K;p.K252N_280_E247K;K252N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMNGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.G254W_280_G254W length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGWPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.P222S_280_P222S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCSATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A13T_280_A13T length=280AA MTMTLHTKASGMTLLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.Y191H_280_Y191H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDHASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.Y73H_280_Y73H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVHGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.S10C_280_S10C length=280AA MTMTLHTKACGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.Y197C_280_Y197C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHCGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R243C_280_R243C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLCKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.L35M_280_L35M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPMERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R233M_280_R233M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNMRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.D190N_280_D190N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNNYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.N217S_280_N217S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHSDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.R263I_280_S263I length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSILMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A207T_280_A207T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKTFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.P113S_280_P113S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHSPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.L31P_280_L31P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQPKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.C240Y_280_C240Y length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAYRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.K206R_280_K206R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCRAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.V187L_280_V187L length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCALCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E56K_280_E56K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPKGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.P152T_280_P152T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RTNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000206249_ENST00000541428_152201906_62416068_5-gene_p.K235N_280_K235N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRNSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.T224N_280_T224N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPANNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A166S_280_A166S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLSSTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.G40V_280_G40V length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLVEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247D_280_E247D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYDVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.P82H_280_P82H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGHGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.K171M_280_K171M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDMGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R142P_280_R142P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVPEAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E41D_280_E41D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGDVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.Q17H_280_Q17H length=280AA MTMTLHTKASGMALLHHIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.H196R_280_H196R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYRYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A239S_280_A239S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQSCRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.N69K_280_N69K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAAKAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.C188R_280_C188R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVRNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R259Q_280_A259Q length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKQRCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.Y52H_280_Y52H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVHNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A9T;p.E247K_280_A9T;E247K length=280AA MTMTLHTKTSGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247K;p.K252N_280_E247K;K252N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMNGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.G254W_280_G254W length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGWPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.P222S_280_P222S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCSATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A13T_280_A13T length=280AA MTMTLHTKASGMTLLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.Y191H_280_Y191H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDHASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.Y73H_280_Y73H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVHGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.S10C_280_S10C length=280AA MTMTLHTKACGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.Y197C_280_Y197C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHCGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R243C_280_R243C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLCKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.L35M_280_L35M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPMERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R233M_280_R233M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNMRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.D190N_280_D190N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNNYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.N217S_280_N217S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHSDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.R263I_280_S263I length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSILMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A207T_280_A207T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKTFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.P113S_280_P113S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHSPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.L31P_280_L31P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQPKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.C240Y_280_C240Y length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAYRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.K206R_280_K206R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCRAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.V187L_280_V187L length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCALCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E56K_280_E56K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPKGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.P152T_280_P152T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RTNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000338799_ENST00000541428_152201906_62416068_5-gene_p.K235N_280_K235N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRNSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.T224N_280_T224N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPANNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A166S_280_A166S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLSSTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.G40V_280_G40V length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLVEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247D_280_E247D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYDVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.P82H_280_P82H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGHGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.K171M_280_K171M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDMGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R142P_280_R142P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVPEAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E41D_280_E41D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGDVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.Q17H_280_Q17H length=280AA MTMTLHTKASGMALLHHIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.H196R_280_H196R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYRYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A239S_280_A239S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQSCRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.N69K_280_N69K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAAKAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.C188R_280_C188R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVRNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R259Q_280_A259Q length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKQRCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.Y52H_280_Y52H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVHNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A9T;p.E247K_280_A9T;E247K length=280AA MTMTLHTKTSGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247K;p.K252N_280_E247K;K252N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMNGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.G254W_280_G254W length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGWPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.P222S_280_P222S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCSATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A13T_280_A13T length=280AA MTMTLHTKASGMTLLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.Y191H_280_Y191H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDHASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.Y73H_280_Y73H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVHGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.S10C_280_S10C length=280AA MTMTLHTKACGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.Y197C_280_Y197C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHCGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R243C_280_R243C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLCKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.L35M_280_L35M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPMERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R233M_280_R233M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNMRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.D190N_280_D190N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNNYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.N217S_280_N217S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHSDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.R263I_280_S263I length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSILMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A207T_280_A207T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKTFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.P113S_280_P113S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHSPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.L31P_280_L31P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQPKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.C240Y_280_C240Y length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAYRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.K206R_280_K206R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCRAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.V187L_280_V187L length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCALCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E56K_280_E56K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPKGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.P152T_280_P152T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RTNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000427531_ENST00000541428_152201906_62416068_5-gene_p.K235N_280_K235N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRNSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.T224N_280_T224N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPANNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A166S_280_A166S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLSSTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.G40V_280_G40V length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLVEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247D_280_E247D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYDVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.P82H_280_P82H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGHGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.K171M_280_K171M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDMGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R142P_280_R142P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVPEAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E41D_280_E41D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGDVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.Q17H_280_Q17H length=280AA MTMTLHTKASGMALLHHIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.H196R_280_H196R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYRYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A239S_280_A239S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQSCRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.N69K_280_N69K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAAKAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.C188R_280_C188R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVRNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R259Q_280_A259Q length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKQRCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.Y52H_280_Y52H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVHNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A9T;p.E247K_280_A9T;E247K length=280AA MTMTLHTKTSGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247K;p.K252N_280_E247K;K252N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMNGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.G254W_280_G254W length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGWPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.P222S_280_P222S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCSATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A13T_280_A13T length=280AA MTMTLHTKASGMTLLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.Y191H_280_Y191H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDHASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.Y73H_280_Y73H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVHGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.S10C_280_S10C length=280AA MTMTLHTKACGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.Y197C_280_Y197C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHCGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R243C_280_R243C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLCKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.L35M_280_L35M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPMERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R233M_280_R233M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNMRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.D190N_280_D190N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNNYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.N217S_280_N217S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHSDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.R263I_280_S263I length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSILMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A207T_280_A207T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKTFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.P113S_280_P113S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHSPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.L31P_280_L31P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQPKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.C240Y_280_C240Y length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAYRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.K206R_280_K206R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCRAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.V187L_280_V187L length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCALCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E56K_280_E56K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPKGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.P152T_280_P152T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RTNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000443427_ENST00000541428_152201906_62416068_5-gene_p.K235N_280_K235N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRNSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.T224N_280_T224N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPANNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A166S_280_A166S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLSSTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.G40V_280_G40V length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLVEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247D_280_E247D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYDVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.P82H_280_P82H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGHGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.K171M_280_K171M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDMGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R142P_280_R142P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVPEAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E41D_280_E41D length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGDVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.Q17H_280_Q17H length=280AA MTMTLHTKASGMALLHHIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.H196R_280_H196R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYRYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A239S_280_A239S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQSCRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.N69K_280_N69K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAAKAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.C188R_280_C188R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVRNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R259Q_280_A259Q length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKQRCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.Y52H_280_Y52H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVHNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A9T;p.E247K_280_A9T;E247K length=280AA MTMTLHTKTSGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247K;p.K252N_280_E247K;K252N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMNGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.G254W_280_G254W length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGWPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.P222S_280_P222S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCSATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A13T_280_A13T length=280AA MTMTLHTKASGMTLLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.Y191H_280_Y191H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDHASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.Y73H_280_Y73H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVHGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.S10C_280_S10C length=280AA MTMTLHTKACGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.Y197C_280_Y197C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHCGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R243C_280_R243C length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLCKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R243H_280_R243H length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLHKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.L35M_280_L35M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPMERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R233M_280_R233M length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNMRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.D190N_280_D190N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNNYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.N217S_280_N217S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHSDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.D218N_280_D218N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNNYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.R263I_280_S263I length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSILMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A207T_280_A207T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKTFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.P113S_280_P113S length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHSPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.L31P_280_L31P length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQPKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.C240Y_280_C240Y length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAYRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.K206R_280_K206R length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCRAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.V187L_280_V187L length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCALCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E56K_280_E56K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPKGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.A68T_280_A68T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAATNAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.P152T_280_P152T length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RTNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.E247K_280_E247K length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYKVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG >ESR1_ASPH_ENST00000456483_ENST00000541428_152201906_62416068_5-gene_p.K235N_280_K235N length=280AA MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFY RPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRNSCQACRLRKCYEVGMMKGGPGRKARCSSLMTPLSTRYGRMPHLSG |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-19-1789-01A | 5-gene | p.T224N | 280 | T224N |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-19-1790-01B | 5-gene | p.A166S | 280 | A166S |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-37-3783-01A | 5-gene | p.G40V | 280 | G40V |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-3N-A9WD-06A | 5-gene | p.E247D | 280 | E247D |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-51-4079-01A | 5-gene | p.P82H | 280 | P82H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-51-4081-01A | 5-gene | p.K171M | 280 | K171M |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-55-8204-01A | 5-gene | p.R142P | 280 | R142P |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-55-8507-01A | 5-gene | p.E41D | 280 | E41D |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-5L-AAT1-01A | 5-gene | p.Q17H | 280 | Q17H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-66-2771-01A | 5-gene | p.H196R | 280 | H196R |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-85-6798-01A | 5-gene | p.A239S | 280 | A239S |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-97-7554-01A | 5-gene | p.N69K | 280 | N69K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-A5-A0G2-01A | 5-gene | p.C188R | 280 | C188R |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-A6-6781-01A | 5-gene | p.R259Q | 280 | A259Q |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AA-3492-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AA-3947-01A | 5-gene | p.Y52H | 280 | Y52H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AA-A010-01A | 5-gene | p.A9T;p.E247K | 280 | A9T;E247K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AG-A002-01A | 5-gene | p.E247K;p.K252N | 280 | E247K;K252N |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AP-A056-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-AP-A059-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-B5-A11E-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-BF-A1PU-01A | 5-gene | p.G254W | 280 | G254W |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-BH-A0DS-01A | 5-gene | p.P222S | 280 | P222S |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-BR-4257-01A | 5-gene | p.A13T | 280 | A13T |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-BS-A0TA-01A | 5-gene | p.Y191H | 280 | Y191H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-BS-A0V4-01A | 5-gene | p.Y73H | 280 | Y73H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-CI-6621-01A | 5-gene | p.S10C | 280 | S10C |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-CN-5358-01A | 5-gene | p.Y197C | 280 | Y197C |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-D3-A3MR-06A | 5-gene | p.R243C | 280 | R243C |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-DC-6681-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-DZ-6131-01A | 5-gene | p.L35M | 280 | L35M |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EE-A184-06A | 5-gene | p.R233M | 280 | R233M |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EE-A3JD-06A | 5-gene | p.E247K | 280 | E247K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EI-6507-01A | 5-gene | p.D190N | 280 | D190N |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EI-6882-01A | 5-gene | p.N217S | 280 | N217S |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EO-A22R-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-EO-A3AY-01A | 5-gene | p.R263I | 280 | S263I |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-F5-6814-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-FI-A2D5-01A | 5-gene | p.A207T | 280 | A207T |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-G4-6315-01A | 5-gene | p.P113S | 280 | P113S |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-HF-7132-01A | 5-gene | p.L31P | 280 | L31P |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-HU-A4G8-01A | 5-gene | p.C240Y | 280 | C240Y |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-IR-A3LA-01A | 5-gene | p.K206R | 280 | K206R |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-KU-A66S-01A | 5-gene | p.V187L | 280 | V187L |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-L5-A4OU-01A | 5-gene | p.E56K | 280 | E56K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-VQ-A91D-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-VQ-A91X-01A | 5-gene | p.P152T | 280 | P152T |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-W3-AA1V-06B | 5-gene | p.E247K | 280 | E247K |
| ENST00000206249_ENST00000541428_152201906_62416068 | TCGA-ZF-AA4W-01A | 5-gene | p.K235N | 280 | K235N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-19-1789-01A | 5-gene | p.T224N | 280 | T224N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-19-1790-01B | 5-gene | p.A166S | 280 | A166S |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-37-3783-01A | 5-gene | p.G40V | 280 | G40V |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-3N-A9WD-06A | 5-gene | p.E247D | 280 | E247D |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-51-4079-01A | 5-gene | p.P82H | 280 | P82H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-51-4081-01A | 5-gene | p.K171M | 280 | K171M |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-55-8204-01A | 5-gene | p.R142P | 280 | R142P |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-55-8507-01A | 5-gene | p.E41D | 280 | E41D |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-5L-AAT1-01A | 5-gene | p.Q17H | 280 | Q17H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-66-2771-01A | 5-gene | p.H196R | 280 | H196R |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-85-6798-01A | 5-gene | p.A239S | 280 | A239S |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-97-7554-01A | 5-gene | p.N69K | 280 | N69K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-A5-A0G2-01A | 5-gene | p.C188R | 280 | C188R |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-A6-6781-01A | 5-gene | p.R259Q | 280 | A259Q |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AA-3492-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AA-3947-01A | 5-gene | p.Y52H | 280 | Y52H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AA-A010-01A | 5-gene | p.A9T;p.E247K | 280 | A9T;E247K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AG-A002-01A | 5-gene | p.E247K;p.K252N | 280 | E247K;K252N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AP-A056-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-AP-A059-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-B5-A11E-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-BF-A1PU-01A | 5-gene | p.G254W | 280 | G254W |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-BH-A0DS-01A | 5-gene | p.P222S | 280 | P222S |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-BR-4257-01A | 5-gene | p.A13T | 280 | A13T |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-BS-A0TA-01A | 5-gene | p.Y191H | 280 | Y191H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-BS-A0V4-01A | 5-gene | p.Y73H | 280 | Y73H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-CI-6621-01A | 5-gene | p.S10C | 280 | S10C |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-CN-5358-01A | 5-gene | p.Y197C | 280 | Y197C |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-D3-A3MR-06A | 5-gene | p.R243C | 280 | R243C |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-DC-6681-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-DZ-6131-01A | 5-gene | p.L35M | 280 | L35M |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EE-A184-06A | 5-gene | p.R233M | 280 | R233M |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EE-A3JD-06A | 5-gene | p.E247K | 280 | E247K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EI-6507-01A | 5-gene | p.D190N | 280 | D190N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EI-6882-01A | 5-gene | p.N217S | 280 | N217S |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EO-A22R-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-EO-A3AY-01A | 5-gene | p.R263I | 280 | S263I |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-F5-6814-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-FI-A2D5-01A | 5-gene | p.A207T | 280 | A207T |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-G4-6315-01A | 5-gene | p.P113S | 280 | P113S |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-HF-7132-01A | 5-gene | p.L31P | 280 | L31P |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-HU-A4G8-01A | 5-gene | p.C240Y | 280 | C240Y |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-IR-A3LA-01A | 5-gene | p.K206R | 280 | K206R |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-KU-A66S-01A | 5-gene | p.V187L | 280 | V187L |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-L5-A4OU-01A | 5-gene | p.E56K | 280 | E56K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-VQ-A91D-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-VQ-A91X-01A | 5-gene | p.P152T | 280 | P152T |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-W3-AA1V-06B | 5-gene | p.E247K | 280 | E247K |
| ENST00000338799_ENST00000541428_152201906_62416068 | TCGA-ZF-AA4W-01A | 5-gene | p.K235N | 280 | K235N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-19-1789-01A | 5-gene | p.T224N | 280 | T224N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-19-1790-01B | 5-gene | p.A166S | 280 | A166S |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-37-3783-01A | 5-gene | p.G40V | 280 | G40V |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-3N-A9WD-06A | 5-gene | p.E247D | 280 | E247D |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-51-4079-01A | 5-gene | p.P82H | 280 | P82H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-51-4081-01A | 5-gene | p.K171M | 280 | K171M |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-55-8204-01A | 5-gene | p.R142P | 280 | R142P |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-55-8507-01A | 5-gene | p.E41D | 280 | E41D |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-5L-AAT1-01A | 5-gene | p.Q17H | 280 | Q17H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-66-2771-01A | 5-gene | p.H196R | 280 | H196R |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-85-6798-01A | 5-gene | p.A239S | 280 | A239S |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-97-7554-01A | 5-gene | p.N69K | 280 | N69K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-A5-A0G2-01A | 5-gene | p.C188R | 280 | C188R |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-A6-6781-01A | 5-gene | p.R259Q | 280 | A259Q |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AA-3492-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AA-3947-01A | 5-gene | p.Y52H | 280 | Y52H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AA-A010-01A | 5-gene | p.A9T;p.E247K | 280 | A9T;E247K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AG-A002-01A | 5-gene | p.E247K;p.K252N | 280 | E247K;K252N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AP-A056-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-AP-A059-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-B5-A11E-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-BF-A1PU-01A | 5-gene | p.G254W | 280 | G254W |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-BH-A0DS-01A | 5-gene | p.P222S | 280 | P222S |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-BR-4257-01A | 5-gene | p.A13T | 280 | A13T |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-BS-A0TA-01A | 5-gene | p.Y191H | 280 | Y191H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-BS-A0V4-01A | 5-gene | p.Y73H | 280 | Y73H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-CI-6621-01A | 5-gene | p.S10C | 280 | S10C |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-CN-5358-01A | 5-gene | p.Y197C | 280 | Y197C |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-D3-A3MR-06A | 5-gene | p.R243C | 280 | R243C |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-DC-6681-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-DZ-6131-01A | 5-gene | p.L35M | 280 | L35M |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EE-A184-06A | 5-gene | p.R233M | 280 | R233M |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EE-A3JD-06A | 5-gene | p.E247K | 280 | E247K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EI-6507-01A | 5-gene | p.D190N | 280 | D190N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EI-6882-01A | 5-gene | p.N217S | 280 | N217S |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EO-A22R-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-EO-A3AY-01A | 5-gene | p.R263I | 280 | S263I |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-F5-6814-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-FI-A2D5-01A | 5-gene | p.A207T | 280 | A207T |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-G4-6315-01A | 5-gene | p.P113S | 280 | P113S |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-HF-7132-01A | 5-gene | p.L31P | 280 | L31P |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-HU-A4G8-01A | 5-gene | p.C240Y | 280 | C240Y |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-IR-A3LA-01A | 5-gene | p.K206R | 280 | K206R |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-KU-A66S-01A | 5-gene | p.V187L | 280 | V187L |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-L5-A4OU-01A | 5-gene | p.E56K | 280 | E56K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-VQ-A91D-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-VQ-A91X-01A | 5-gene | p.P152T | 280 | P152T |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-W3-AA1V-06B | 5-gene | p.E247K | 280 | E247K |
| ENST00000427531_ENST00000541428_152201906_62416068 | TCGA-ZF-AA4W-01A | 5-gene | p.K235N | 280 | K235N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-19-1789-01A | 5-gene | p.T224N | 280 | T224N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-19-1790-01B | 5-gene | p.A166S | 280 | A166S |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-37-3783-01A | 5-gene | p.G40V | 280 | G40V |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-3N-A9WD-06A | 5-gene | p.E247D | 280 | E247D |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-51-4079-01A | 5-gene | p.P82H | 280 | P82H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-51-4081-01A | 5-gene | p.K171M | 280 | K171M |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-55-8204-01A | 5-gene | p.R142P | 280 | R142P |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-55-8507-01A | 5-gene | p.E41D | 280 | E41D |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-5L-AAT1-01A | 5-gene | p.Q17H | 280 | Q17H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-66-2771-01A | 5-gene | p.H196R | 280 | H196R |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-85-6798-01A | 5-gene | p.A239S | 280 | A239S |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-97-7554-01A | 5-gene | p.N69K | 280 | N69K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-A5-A0G2-01A | 5-gene | p.C188R | 280 | C188R |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-A6-6781-01A | 5-gene | p.R259Q | 280 | A259Q |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AA-3492-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AA-3947-01A | 5-gene | p.Y52H | 280 | Y52H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AA-A010-01A | 5-gene | p.A9T;p.E247K | 280 | A9T;E247K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AG-A002-01A | 5-gene | p.E247K;p.K252N | 280 | E247K;K252N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AP-A056-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-AP-A059-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-B5-A11E-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-BF-A1PU-01A | 5-gene | p.G254W | 280 | G254W |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-BH-A0DS-01A | 5-gene | p.P222S | 280 | P222S |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-BR-4257-01A | 5-gene | p.A13T | 280 | A13T |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-BS-A0TA-01A | 5-gene | p.Y191H | 280 | Y191H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-BS-A0V4-01A | 5-gene | p.Y73H | 280 | Y73H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-CI-6621-01A | 5-gene | p.S10C | 280 | S10C |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-CN-5358-01A | 5-gene | p.Y197C | 280 | Y197C |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-D3-A3MR-06A | 5-gene | p.R243C | 280 | R243C |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-DC-6681-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-DZ-6131-01A | 5-gene | p.L35M | 280 | L35M |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EE-A184-06A | 5-gene | p.R233M | 280 | R233M |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EE-A3JD-06A | 5-gene | p.E247K | 280 | E247K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EI-6507-01A | 5-gene | p.D190N | 280 | D190N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EI-6882-01A | 5-gene | p.N217S | 280 | N217S |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EO-A22R-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-EO-A3AY-01A | 5-gene | p.R263I | 280 | S263I |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-F5-6814-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-FI-A2D5-01A | 5-gene | p.A207T | 280 | A207T |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-G4-6315-01A | 5-gene | p.P113S | 280 | P113S |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-HF-7132-01A | 5-gene | p.L31P | 280 | L31P |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-HU-A4G8-01A | 5-gene | p.C240Y | 280 | C240Y |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-IR-A3LA-01A | 5-gene | p.K206R | 280 | K206R |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-KU-A66S-01A | 5-gene | p.V187L | 280 | V187L |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-L5-A4OU-01A | 5-gene | p.E56K | 280 | E56K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-VQ-A91D-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-VQ-A91X-01A | 5-gene | p.P152T | 280 | P152T |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-W3-AA1V-06B | 5-gene | p.E247K | 280 | E247K |
| ENST00000443427_ENST00000541428_152201906_62416068 | TCGA-ZF-AA4W-01A | 5-gene | p.K235N | 280 | K235N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-19-1789-01A | 5-gene | p.T224N | 280 | T224N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-19-1790-01B | 5-gene | p.A166S | 280 | A166S |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-37-3783-01A | 5-gene | p.G40V | 280 | G40V |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-3N-A9WD-06A | 5-gene | p.E247D | 280 | E247D |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-51-4079-01A | 5-gene | p.P82H | 280 | P82H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-51-4081-01A | 5-gene | p.K171M | 280 | K171M |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-55-8204-01A | 5-gene | p.R142P | 280 | R142P |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-55-8507-01A | 5-gene | p.E41D | 280 | E41D |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-5L-AAT1-01A | 5-gene | p.Q17H | 280 | Q17H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-66-2771-01A | 5-gene | p.H196R | 280 | H196R |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-85-6798-01A | 5-gene | p.A239S | 280 | A239S |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-97-7554-01A | 5-gene | p.N69K | 280 | N69K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-A5-A0G2-01A | 5-gene | p.C188R | 280 | C188R |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-A6-6781-01A | 5-gene | p.R259Q | 280 | A259Q |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AA-3492-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AA-3947-01A | 5-gene | p.Y52H | 280 | Y52H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AA-A010-01A | 5-gene | p.A9T;p.E247K | 280 | A9T;E247K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AG-A002-01A | 5-gene | p.E247K;p.K252N | 280 | E247K;K252N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AP-A056-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-AP-A059-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-B5-A11E-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-BF-A1PU-01A | 5-gene | p.G254W | 280 | G254W |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-BH-A0DS-01A | 5-gene | p.P222S | 280 | P222S |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-BR-4257-01A | 5-gene | p.A13T | 280 | A13T |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-BS-A0TA-01A | 5-gene | p.Y191H | 280 | Y191H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-BS-A0V4-01A | 5-gene | p.Y73H | 280 | Y73H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-CI-6621-01A | 5-gene | p.S10C | 280 | S10C |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-CN-5358-01A | 5-gene | p.Y197C | 280 | Y197C |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-D3-A3MR-06A | 5-gene | p.R243C | 280 | R243C |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-DC-6681-01A | 5-gene | p.R243H | 280 | R243H |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-DZ-6131-01A | 5-gene | p.L35M | 280 | L35M |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EE-A184-06A | 5-gene | p.R233M | 280 | R233M |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EE-A3JD-06A | 5-gene | p.E247K | 280 | E247K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EI-6507-01A | 5-gene | p.D190N | 280 | D190N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EI-6882-01A | 5-gene | p.N217S | 280 | N217S |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EO-A22R-01A | 5-gene | p.D218N | 280 | D218N |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-EO-A3AY-01A | 5-gene | p.R263I | 280 | S263I |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-F5-6814-01A | 5-gene | p.E247K | 280 | E247K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-FI-A2D5-01A | 5-gene | p.A207T | 280 | A207T |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-G4-6315-01A | 5-gene | p.P113S | 280 | P113S |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-HF-7132-01A | 5-gene | p.L31P | 280 | L31P |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-HU-A4G8-01A | 5-gene | p.C240Y | 280 | C240Y |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-IR-A3LA-01A | 5-gene | p.K206R | 280 | K206R |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-KU-A66S-01A | 5-gene | p.V187L | 280 | V187L |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-L5-A4OU-01A | 5-gene | p.E56K | 280 | E56K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-VQ-A91D-01A | 5-gene | p.A68T | 280 | A68T |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-VQ-A91X-01A | 5-gene | p.P152T | 280 | P152T |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-W3-AA1V-06B | 5-gene | p.E247K | 280 | E247K |
| ENST00000456483_ENST00000541428_152201906_62416068 | TCGA-ZF-AA4W-01A | 5-gene | p.K235N | 280 | K235N |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
Top |
Fusion Gene Exprssed Samples for ESR1_ASPH |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416067 | - | |
| ChimerDB | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | - | ASPH | chr8 | 62416068 | - | |
| ChimerDB | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | |
| ChimerDB | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | |
| ChimerDB | BRCA | TCGA-A2-A3KD | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | |
| TCGAfusionPortal | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | |
| WashU | BRCA | TCGA-A2-A3KD-01A | ESR1 | chr6 | 152201906 | + | ASPH | chr8 | 62416068 | - | |
| cBioPortal | BRCA_TCGA_PAN_CAN_ATLAS_2018 | BRCA | TCGA-A2-A3KD-01 | ESR1 | chr6 | 151880771 | ASPH | chr8 | 61503509 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
Top |
Related Drugs for ESR1_ASPH |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies