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Fusion gene:C6orf136_AKR1C1 (FusionGDB2 ID:HG221545TG1645) |
Fusion Gene Summary for C6orf136_AKR1C1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: C6orf136_AKR1C1 | Fusion gene ID: hg221545tg1645 | Hgene | Tgene | Gene symbol | C6orf136 | AKR1C1 | Gene ID | 221545 | 1645 |
| Gene name | chromosome 6 open reading frame 136 | aldo-keto reductase family 1 member C1 | |
| Synonyms | - | 2-ALPHA-HSD|20-ALPHA-HSD|C9|DD1|DD1/DD2|DDH|DDH1|H-37|HAKRC|HBAB|MBAB | |
| Cytomap | 6p21.33 | 10p15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | uncharacterized protein C6orf136 | aldo-keto reductase family 1 member C120 alpha-hydroxysteroid dehydrogenasealdo-keto reductase Cchlordecone reductase homolog HAKRCdihydrodiol dehydrogenase 1dihydrodiol dehydrogenase 1/2dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid | |
| Modification date | 20240305 | 20240411 | |
| UniProtAcc | Q5SQH8 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000293604, ENST00000376473, ENST00000528347, ENST00000376471, ENST00000383580, ENST00000383581, ENST00000415931, ENST00000417076, ENST00000417649, ENST00000419321, ENST00000422530, ENST00000425581, ENST00000430141, ENST00000447505, ENST00000455682, ENST00000456444, ENST00000459700, ENST00000466518, ENST00000472341, ENST00000486177, ENST00000491140, ENST00000493705, ENST00000496234, ENST00000546452, ENST00000547308, ENST00000549361, ENST00000549800, ENST00000549861, ENST00000552569, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 3 X 5 X 3=45 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 7 X 14 X 10=980 |
| # samples | 5 | 19 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(5/45*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(19/980*10)=-2.36678233067162 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: C6orf136 [Title/Abstract] AND AKR1C1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | C6orf136(30617736)-AKR1C1(5008105), # samples:1 | ||
| Fusion gene breakpoints across C6orf136 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across AKR1C1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Breakpoints for C6orf136_AKR1C1 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 30617736 |
| C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008106 |
| C6ORF136 | chr6 | 30649959 | AKR1C1 | chr10 | 4965914 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for C6orf136_AKR1C1 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| C6orf136-AKR1C1 | Promoter / Enhancer Hijacking M6 | Promoter swap drives high aldo-keto reductase AKR1C1 expression, accelerating detoxification of cytotoxic chemotherapy drugs. | AKR1C inhibitors; platinum-based chemotherapy | Chemoresistant ovarian and lung carcinomas |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| C6orf136-AKR1C1 | Promoter / Enhancer Hijacking | Promoter swap drives high aldo-keto reductase AKR1C1 expression, accelerating detoxification of cytotoxic chemotherapy drugs. | Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 40015157; Title: Discovery of highly potent AKR1Cs pan-inhibitors as chemotherapeutic potentiators to restore breast cancer drug resistance.; PMID: 41756011; Title: Comprehensive analysis of the deleterious nonsynonymous, non-coding SNPs and cancer variants of human aldo-keto reductase type 1 (AKR1C1) protein and their probable association with disease risk and progression: a computational study. | AKR1C inhibitors; platinum-based chemotherapy | Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 40015157; Title: Discovery of highly potent AKR1Cs pan-inhibitors as chemotherapeutic potentiators to restore breast cancer drug resistance. | Chemoresistant ovarian and lung carcinomas |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| C6orf136 | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | AKR1C1 | GO:0007586 | digestion | 8486699 |
| Tgene | AKR1C1 | GO:0008206 | bile acid metabolic process | 8486699 |
| Tgene | AKR1C1 | GO:0030855 | epithelial cell differentiation | 21492153 |
| Tgene | AKR1C1 | GO:0042448 | progesterone metabolic process | 21232532 |
| Tgene | AKR1C1 | GO:0042574 | retinal metabolic process | 21851338 |
| Tgene | AKR1C1 | GO:0071395 | cellular response to jasmonic acid stimulus | 19487289 |
| Tgene | AKR1C1 | GO:2000379 | positive regulation of reactive oxygen species metabolic process | 19442656 |
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Fusion Genomic Features for C6orf136_AKR1C1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + | 1.58e-02 | 9.84e-01 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for C6orf136_AKR1C1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000293604 | ENST00000380859 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000293604 | ENST00000380872 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000293604 | ENST00000477661 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000376473 | ENST00000380859 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000376473 | ENST00000380872 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000376473 | ENST00000477661 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000528347 | ENST00000380859 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000528347 | ENST00000380872 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| 5CDS-3UTR | ENST00000528347 | ENST00000477661 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| In-frame | ENST00000293604 | ENST00000434459 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| In-frame | ENST00000376473 | ENST00000434459 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| In-frame | ENST00000528347 | ENST00000434459 | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008105 | + |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000293604 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 1210 | 358 |
| ENST00000376473 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 633 | 634 |
| ENST00000528347 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 45 | 453 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000293604 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 9.08e-04 | 9.99e-01 |
| ENST00000376473 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 8.62e-04 | 9.99e-01 |
| ENST00000528347 | ENST00000434459 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 1.33e-03 | 9.99e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000293604 | ENST00000380859 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 8.00e-03 |
| ENST00000293604 | ENST00000380872 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 4.09e-03 |
| ENST00000293604 | ENST00000477661 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 3.38e-01 |
| ENST00000376473 | ENST00000380859 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 7.27e-03 |
| ENST00000376473 | ENST00000380872 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 1.08e-02 |
| ENST00000376473 | ENST00000477661 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 8.54e-02 |
| ENST00000528347 | ENST00000380859 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 9.35e-03 |
| ENST00000528347 | ENST00000380872 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 2.01e-02 |
| ENST00000528347 | ENST00000477661 | C6orf136 | chr6 | 30617736 | AKR1C1 | chr10 | 5008105 | 0.00e+00 | 9.88e-01 |
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Fusion Protein Retained/Non-Retained Functional Features for C6orf136_AKR1C1 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
C6orf136_AKR1C1_chr6-30617736_chr10-5008105.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for C6orf136_AKR1C1 |
| In-frame Fusion Transcript Sequences. |
>C6orf136_AKR1C1_ENST00000293604_ENST00000434459_30617736_5008105 length=2306nt Breakpoint=1210nt CTTCAGCCGCTTCCCTCGAGCCTGCAGTGCGCAAGCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCC GGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCCCGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGTGAGCGGAGGAGAAGAGGGAGGGAGGAGAGGGGG CGGGGAGAGACCCTCCTCAAAGCCGGTGCGTGGGGCGGAGCGCGCGCTGGGTTCCGCGCAGGCGCAGAGACACCCGCCGCCCCTTCCCACCTGTGCCCTGCAGCGCGTGGACAGGCTAGGGGTCGCGGGAGCGGGAGGGAGGCGCTGCCG GGCCTGTCGCGCAAGGACGTCGGTCCTCCCAGGTTTGAGGGCGGTCAGGCGGGGTCAAGGCCAGGCAGCGGGGCGCGTCTGCGTTGCGCCCGACTCTCCGCGGTTACCTGTGCCTAGAGGTGATTTGAAGGGCAGGGGCCGAGAGATTCG TAGCCCTGCTGCGGCGCCGTCCCGGAGTTCCCCGGCCCAGACCAGACCCGCGGGGCGCCCTCAGCAGCCCGCCCGTCTTGCACTCGGAGAGCGGTCCTGGCAGGAAGGCCGGCCAGTGTGCACCCGGTTCGGGCCCCTGCGCCCGGGCTG GCAAGATGGCCACGCCCCCAGCAGAGACGGCGCCTCTAGGACACCATCGGGGACCGAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCATCTTCTCCTCTATTCTGGTCTCC CCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCTGAGTTGCATAGCGGCTGCCTGGA TGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACATCTGTCTGTCATGTATGAGAGACT GAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAA GAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGG TGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGAT GATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTGGTTGCCTATAGTGCTCTGGGATCCCACCGAGAAGA ACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGTGGGGTTGTGGTCCTGGCCAAGAGCTACAATGAGCA GCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGCCCCCCTAATTATCCATTTTCTGATGAATATTAACA TGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGTGATTTCAGCAAGCTACAGCAAAGCCCATTGGCCAG AAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCT >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105 length=1729nt Breakpoint=633nt GCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCCGGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCC CGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCA TCTTCTCCTCTATTCTGGTCTCCCCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCT GAGTTGCATAGCGGCTGCCTGGATGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACAT CTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGC AAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCAT TTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAAC TTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTGGTTGCCTATAGT GCTCTGGGATCCCACCGAGAAGAACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGTGGGGTTGTGGTC CTGGCCAAGAGCTACAATGAGCAGCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGCCCCCCTAATTAT CCATTTTCTGATGAATATTAACATGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGTGATTTCAGCAAG CTACAGCAAAGCCCATTGGCCAGAAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCT >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105 length=1141nt Breakpoint=45nt ATGGAGGAACATCTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTG GCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTC TACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATC GGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTG GTTGCCTATAGTGCTCTGGGATCCCACCGAGAAGAACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGT GGGGTTGTGGTCCTGGCCAAGAGCTACAATGAGCAGCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGC CCCCCTAATTATCCATTTTCTGATGAATATTAACATGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGT GATTTCAGCAAGCTACAGCAAAGCCCATTGGCCAGAAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCT |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
>C6orf136_AKR1C1_ENST00000293604_ENST00000380859_30617736_5008105 length=1963nt Breakpoint=1210nt CTTCAGCCGCTTCCCTCGAGCCTGCAGTGCGCAAGCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCC GGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCCCGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGTGAGCGGAGGAGAAGAGGGAGGGAGGAGAGGGGG CGGGGAGAGACCCTCCTCAAAGCCGGTGCGTGGGGCGGAGCGCGCGCTGGGTTCCGCGCAGGCGCAGAGACACCCGCCGCCCCTTCCCACCTGTGCCCTGCAGCGCGTGGACAGGCTAGGGGTCGCGGGAGCGGGAGGGAGGCGCTGCCG GGCCTGTCGCGCAAGGACGTCGGTCCTCCCAGGTTTGAGGGCGGTCAGGCGGGGTCAAGGCCAGGCAGCGGGGCGCGTCTGCGTTGCGCCCGACTCTCCGCGGTTACCTGTGCCTAGAGGTGATTTGAAGGGCAGGGGCCGAGAGATTCG TAGCCCTGCTGCGGCGCCGTCCCGGAGTTCCCCGGCCCAGACCAGACCCGCGGGGCGCCCTCAGCAGCCCGCCCGTCTTGCACTCGGAGAGCGGTCCTGGCAGGAAGGCCGGCCAGTGTGCACCCGGTTCGGGCCCCTGCGCCCGGGCTG GCAAGATGGCCACGCCCCCAGCAGAGACGGCGCCTCTAGGACACCATCGGGGACCGAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCATCTTCTCCTCTATTCTGGTCTCC CCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCTGAGTTGCATAGCGGCTGCCTGGA TGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACATCTGTCTGTCATGTATGAGAGACT GAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAA GAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGG TGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGAT GATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGCCTAGAGATAATTCCATCTTTTCCTTGAGTCCTGACTGGTGATTCCAGGCCTCCTTGATCAAATTGACTGTCCCCAAATGTTACACACATTTCAGCATTAAAGT TACTACACTTTTCCCAGTAAATTACATTTTTTTGTTTTATTTTATGTTTTAAAACTTAGAGTCAATCAGTGAAGATCTACAGTGGAAATACATATGTATAAAATTAGTGAATTTGGTATAATGATACGGTGCTGTGATAATTTAATAAAA GCATTGAGAAATT >C6orf136_AKR1C1_ENST00000293604_ENST00000380872_30617736_5008105 length=7639nt Breakpoint=1210nt CTTCAGCCGCTTCCCTCGAGCCTGCAGTGCGCAAGCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCC GGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCCCGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGTGAGCGGAGGAGAAGAGGGAGGGAGGAGAGGGGG CGGGGAGAGACCCTCCTCAAAGCCGGTGCGTGGGGCGGAGCGCGCGCTGGGTTCCGCGCAGGCGCAGAGACACCCGCCGCCCCTTCCCACCTGTGCCCTGCAGCGCGTGGACAGGCTAGGGGTCGCGGGAGCGGGAGGGAGGCGCTGCCG GGCCTGTCGCGCAAGGACGTCGGTCCTCCCAGGTTTGAGGGCGGTCAGGCGGGGTCAAGGCCAGGCAGCGGGGCGCGTCTGCGTTGCGCCCGACTCTCCGCGGTTACCTGTGCCTAGAGGTGATTTGAAGGGCAGGGGCCGAGAGATTCG TAGCCCTGCTGCGGCGCCGTCCCGGAGTTCCCCGGCCCAGACCAGACCCGCGGGGCGCCCTCAGCAGCCCGCCCGTCTTGCACTCGGAGAGCGGTCCTGGCAGGAAGGCCGGCCAGTGTGCACCCGGTTCGGGCCCCTGCGCCCGGGCTG GCAAGATGGCCACGCCCCCAGCAGAGACGGCGCCTCTAGGACACCATCGGGGACCGAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCATCTTCTCCTCTATTCTGGTCTCC CCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCTGAGTTGCATAGCGGCTGCCTGGA TGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACATCTGTCTGTCATGTATGAGAGACT GAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAA GAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGG TGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGAT GATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTGGTTGCCTATAGTGCTCTGGGATCCCACCGAGAAGA ACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGTGGGGTTGTGGTCCTGGCCAAGAGCTACAATGAGCA GCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGCCCCCCTAATTATCCATTTTCTGATGAATATTAACA TGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGTGATTTCAGCAAGCTACAGCAAAGCCCATTGGCCAG AAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCTAAAGATTCTTCACCTACTTTGGTCTCCATAACTTCTATGTTTTCTTTCCTTCTGACACACTAGTGCCCCTAAATTGTGATTTGCCTATACGTTT AGGGCCGGGGTTGGAAGATGTTAACAACCATTTAAGATTCATTTCTGCAGTGGGAGTGGGTGGAGTTTCACCCTCTGGGAAAGGGGCAGGTGACAGGTATTTATCAGTCAGTGCCTCTCTAGCTCTTGTAGGAAGAAGCACACGCAGGAT GGAGTCTAGAGGATGAGCGATATTGACTAGCAATTCATGGGCTCCCTCCAGCAGTGCGAGGGTCAGAGTTTCTGGAGCCTTGGGAGGAGGCATCCCTGTGAGGGGGGGTTAGGGAGATGGGAGGGCACCAGGAAAAGTGATTAGAAGTCA GGTATGGGAAGGCTAAATAGGACAGAGTCGAGTACATCTCTGCTTGGAAAAACATATCAACACCCTTTTTTTTGAACATTATATCTTGCTCATAAAAGAAAACTTTCCACATTGTTTTAACAAACCCCACAGCTGAGAGTCAGGCCTGAA TCTTTGATGTGTGCCCATTCACAACGTTGACCCTATTGGTTTGTGGTGGGGCAGGGCATCAAAGACATCATTGACTAATCACATTCCCCTGAATAGCTCATATTTAGAAAATATTCTTAGATTCTAAAAATGTACTATTAATTTGTGATA TTCAGTCTTTTAAATATTTTATACATTAAACAGGCATAGTTACAAATATAAAACAAAAATATCCCAAAGCCATTATGCATGGCACTCAAGATTAAAATGGGAAATAATACATCTAATAAATCAAATGTTCCAAGACTTCAAAGGTCTTTT GGAAACAGGCTATGTAAAACAGCACACTGGTTTCAAACTTTGGTAAATTTTAAGAACAACTCTTACAAAGGCATTTAATTCTTATACATAATTTTCAGGGGACCTAAGTTAATCAGCTAATCATGAAGACATGATTTTCATTTTAGAAAA CACTTTTGAAAACTTGGGATAATCTCATGCCTTAATGATCAAAGCATTATGAGAAGGACAGTGGTTTTTAACCTGGGCATATGTTCTAACACATTTACTCTCCACTATTCGTACTCTGGTAGCCATGTTAACCCCATCAGAGATTCCTTC TCAAGCCATGTCTCAGAGCTGAGAGGCATCCCAGCAAGTTTTGCAGCTCACAGTTTTTTCCGTAAATTACTTATTCTATAAAATTGGAGTAGGCCATAAACTTTGGAGGGCCCTAGACCAATTTTTTGGATTATTTTTCGTCTTCTATCA TTCCGCTGATCTTAGATATTCTCTGCATTAAATATTAAATATCACTTCTAGGCTGAAAAATCCCCCTAAAAATATTTCTAGCTCAGATTTTTCCTCCAAATTCTGCAATAGAAGATCACAATGTGAACTCTGCATCTCCATGTTAAAGTC TAATGGACATTCACACTTAGCATGTCTCAAAGAAATCTCATGTAAACCATGGCCATCCTGTTCTACCTTAACTTTCTGAGTCTATGGAATGATAATTTCACATCTCATAAACTTGACTGATGTAAGTGTCAAGAAAAGATTGACATTTTG TTAAAAGTTAGTAGTGAAGTGTGTAACGCTTAAGCAAACTTTCATATTTCAAATCTCTTTAGCAAGTGTAACTCTTTTTTCAAGATGTGAAATAATCATTAGGTCAGTCATTTGTAAATAGTACATCTGCTATGGACTTTTTCCAGTTCT TCACCATCCATTTTTATAAAACTCTTATTGTTAAAAAAAAAGTTACTCAGAATTTCATAAAGCCAAACACCTGATTTCAGGAACACTTGAGATGTAAGAAAATTTTATAGGGACCTCCAATCACTAATTTTCCTATTTTTTCTCTCAAAG AAATGCTGAAGGGAGGAATTCAGGTTGAATGAAAGGAAATAGTAACTTACAGCCATATAGAGTTATAAAGACTTCTTGTAAATGTGAACATATGGTAAAATATAAAAACATGTATTTTTGAAATTTTGGATTCTACTCATTATTTTACTT CAATTTAAGATATAAATGTATAGAAATAAGTATAATTCTAAGCTAATACGTATGCAATGTAGGAAGCTGTAATTACTGACCAAAACTATGTGAAGTGGAGAAAACCTGGGGAAGTGGATGGTTTTAGATGAAACTGAAGTTAAATTCATA TTGATTTAAAGTAAATTGTTATAACTTTATAAAGTTTTTCATCATCACCACAGCAATCACAAAGAGAATAATTATGAATATACGCAAGAGGAAATGAGAAGGGAATCCAAATGTCATTAAAAAAAAATCACGCCACCTCACAAAATGGTA ACAGTGGATATAAAGGATAGAAAGCTATAAACCTGGTAGGAAAACATTGAAAATGGCACAAGTGACTCCTTCCCTGTCACCAATGACAGTCATGTGTTGCATAATGCCTGGGCTATCTTCTGAGAATGGCTTTGTTAGGCAACTGTGTCA TGGTGGGGACATGATAGCATTAGAGAGAATTCTCTCAAACACTGTCATGGCCTTATCAACTATGCTTCTGTAATATTCTGAATCCTTCGCTGCCTTTCCAACAGTGTTTACAACGGTTTCCTAAGAAATGAAATCCATTTCACCAAACCA CTTTTCTTGCTCATCCATAAGAAACACTTCTCCTTTGTTAAAATTACATCATGAGATTGCAAGCATTCAGTAACTTGCAAGCTCCAATTTGAATTCTAGTTGTCTTGCTATTTCCACCACATCTGCAATTACTTTCTCCACTGAAATCTT GCATTCCTCCAAGTCATCCAGGAGGGTTGAATTCACTTCTTTCAAACTCCTGTTCAAGTAAATGTTTTGCCCTCCTGTCACGAATCATGAATGTTTTTAATGGCATCTAGAATAGTAAATCTTTTTCAGAAGATTTTCAATTTTCTTTTC CCAGGTTCTTCAGACAAGTCACCATGGTAGCTGTAGACTTATGAAATGTATTTCCTGAACCATAAAACAAGAACATCAAAATTACTCTATGATCCATGGGAAACAGAATGCATGTTGTGTTAGCAGGCATGGAAAGAACAGTAATCTCTT TCAACCTCTGTAAGAGAGTTCTTGGTTGATTAGGTACCTTGTCGATAGGCAGTTCTAATTTCAAAGAACTTTTTCTTTTGCTGAGCAGTAAGTCTTAACAGTGGGCTTAAAATATTCAGTAAACCATTATTTAAGGAGATGTGGCTTAAA TATCTAGGCTTTCTTGCTTTATTTATAGAACACTTACAGAGTAGATATAGATTAAATCTTAAGGACCCTAGGATTGTTAGAATAGTAAATGAACATCATATGTTGTAATATAGTTAGCCAGGGAGGGGAAAGATCTCTACAAGAAATAAT TTTAAAAACTACTCAAAGAAATCAGAGATATCACAAAATGACAAAACAAGTACAGGGGCAGCAAAAGGTAACAGATGTCAACTATGAGATCTCATCAAGAACTAAGAAAATGGAGAAAAGTACCAGATGGCAGATGGGAGGCAGTGTGAG CATGCCTCTCCCACTTGGAGATTAGTGTGTAGAGATTTACATTGTGAATTTCTTTTCAAGAACCAATGCAGAGACTTAACAGATATATGAAAAAATTTCACATACACTCTGAAGAAGTCTCAGGCACAATCCTACTCCATGAAATAAGAA AAAACCATCACATCCCCAGATTCTGAGGGGAGAGAGTTCACTCCAGAGCATACATCCCCACTGGGGATCTGGAAATTCAGGCCACAAGAGAAGGCTTTGATCCTGTGCGGACAAGTGCCTTGAGCAGAATCCACAGGGGAGAGCTGGAAG TGCATGGCAGATATGAGCACAGAAGCTGGGTGTCCAGCCTTGTGGGCAGACCGGGAGGGATGTGGCCTGAAAGCCATGGTTATTATCTCAGCGTGTAAGCTGATGATCTGAGGCTGGTCAGAGTTCTGTGCGCAGACTGCCTGGATGTAA ACCTGGCACTGTTAGCAGAGCACTGCATGAATGAAAGGAATGAAAATAGCCTTGCCAACTGCATAGGTGCTGGGTGAGGCTCACTGTGGGGGGCGCACGGCAAGCTATTCAACATTACGTACAGGCATTTGAGGTCGGGGCATGGAAAAA TACTGAGGCAGTGTGTGTATGTTATTTGTGCTGAGAATGAAACTCCTTGACCTTGAAAACAGGACAGGGAGTGGTGTGTGTGCTGTGATAAGGAATGCTGAAAACGGTCTCCTGAGAATGCGGTTTGAGTGCTTTTACAAGGCCACAGGT GTCTCACGACCTGACCTCATAAAGCCATCTAGTGGATGTTTGTGGCTTAACAAGCCCCTTCAATAAGTACTTGGCGGAGGGATGCTGGGGGGACCTTCTTAGAAGAGCTGCGCCCCACCCCCCTCCCTGGACAGCCCAGCTACAATTGTC TGAGAACTCACTGCAAGCTGTAAGCGGCCCACTACTTCCCACTCCCTTTTTTGAACTCTTCTGTGCAGCAGAGGCAATTAAACTCTCCTCTGGAACATTACCCCAGCAGCCTGAGAACCACCCCTTGGCGCTCACAGGGGCTGCAGCCTG CCTTATCCAAGGACAGTTAGAGTGCAGACCCACCTAACCCTGGACCCACTGGTGGTACCCATCCACCCATCCTGGTAGCTTAACACAAAGATACACTTTTAGGAGCTTCATAGCCCCTCTTCCCCCATTGCCTGAGAAACCACTTTCCCT GGGCAACTTAGGGCAAGCTCAAATCCCACTGCTACCACCACAGCTGGTGCTCTTTTGCAAGTGCCACCTCCTAGCTGGAGACCAACCAGCACAGTCCACACAGCACCTCAAGGAAGAATAAATAGAACTGTTCCCAGGAAGGAGAAAATG CCTGCATGAGCTCAGCTGTTACCACTGCGTACCACACCCTGACCAGTCAGAGGTCTTGAGTCGGTCCGCATGACAAGTTCACCGCTCGCATAACCAGCATTCAAGAAAGCCAGCACACTAAGCCTATCTACAGCCAGGGAGTCTCAGAGT CTACGTCACTCCCCTGCCACCTCAATCAGAGCTGGTGCTGGTATCCACTGCTGGGAGACTTGTGCTGAGGTGAAGCCTGGGCTGGATGGCTGGAGGATGAAGAACTGCACGGAGGAGATGGAGGCACCCAGACAGATGCCCCATGGACAT CCTGAAGCAGAGCTGCCTCACTGCCCTGCACACACATGAGAGCGCAGCCAGGAACAGAAGGACTGGGCAACATTCAGGCGGAGCCCAGGCCAATTTTCTAAACATGGAATATGAGTTAAATAAATGGCTTCGTATTAAA >C6orf136_AKR1C1_ENST00000293604_ENST00000477661_30617736_5008105 length=1210nt Breakpoint=1210nt CTTCAGCCGCTTCCCTCGAGCCTGCAGTGCGCAAGCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCC GGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCCCGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGTGAGCGGAGGAGAAGAGGGAGGGAGGAGAGGGGG CGGGGAGAGACCCTCCTCAAAGCCGGTGCGTGGGGCGGAGCGCGCGCTGGGTTCCGCGCAGGCGCAGAGACACCCGCCGCCCCTTCCCACCTGTGCCCTGCAGCGCGTGGACAGGCTAGGGGTCGCGGGAGCGGGAGGGAGGCGCTGCCG GGCCTGTCGCGCAAGGACGTCGGTCCTCCCAGGTTTGAGGGCGGTCAGGCGGGGTCAAGGCCAGGCAGCGGGGCGCGTCTGCGTTGCGCCCGACTCTCCGCGGTTACCTGTGCCTAGAGGTGATTTGAAGGGCAGGGGCCGAGAGATTCG TAGCCCTGCTGCGGCGCCGTCCCGGAGTTCCCCGGCCCAGACCAGACCCGCGGGGCGCCCTCAGCAGCCCGCCCGTCTTGCACTCGGAGAGCGGTCCTGGCAGGAAGGCCGGCCAGTGTGCACCCGGTTCGGGCCCCTGCGCCCGGGCTG GCAAGATGGCCACGCCCCCAGCAGAGACGGCGCCTCTAGGACACCATCGGGGACCGAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCATCTTCTCCTCTATTCTGGTCTCC CCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCTGAGTTGCATAGCGGCTGCCTGGA TGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACATCTGTCTGTCATGTATGAGAGACT GAGACAAGAG >C6orf136_AKR1C1_ENST00000376473_ENST00000380859_30617736_5008105 length=1386nt Breakpoint=633nt GCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCCGGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCC CGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCA TCTTCTCCTCTATTCTGGTCTCCCCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCT GAGTTGCATAGCGGCTGCCTGGATGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACAT CTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGC AAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCAT TTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAAC TTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGCCTAGAGATAATTCCATCTTTTCCTTGAGTCCTGACTGGTGATTCCAGGCCTCCTTGATCAAATTGACTGTCCCCAAATGT TACACACATTTCAGCATTAAAGTTACTACACTTTTCCCAGTAAATTACATTTTTTTGTTTTATTTTATGTTTTAAAACTTAGAGTCAATCAGTGAAGATCTACAGTGGAAATACATATGTATAAAATTAGTGAATTTGGTATAATGATAC GGTGCTGTGATAATTTAATAAAAGCATTGAGAAATT >C6orf136_AKR1C1_ENST00000376473_ENST00000380872_30617736_5008105 length=7062nt Breakpoint=633nt GCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCCGGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCC CGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCA TCTTCTCCTCTATTCTGGTCTCCCCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCT GAGTTGCATAGCGGCTGCCTGGATGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACAT CTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTGGCCATCCGAAGC AAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTCTACCTTATTCAT TTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATCGGGGTGTCCAAC TTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTGGTTGCCTATAGT GCTCTGGGATCCCACCGAGAAGAACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGTGGGGTTGTGGTC CTGGCCAAGAGCTACAATGAGCAGCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGCCCCCCTAATTAT CCATTTTCTGATGAATATTAACATGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGTGATTTCAGCAAG CTACAGCAAAGCCCATTGGCCAGAAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCTAAAGATTCTTCACCTACTTTGGTCTCCATAACTTCTATGTTTTCTTTCCTTCTGACACACTAGTGCCCCTA AATTGTGATTTGCCTATACGTTTAGGGCCGGGGTTGGAAGATGTTAACAACCATTTAAGATTCATTTCTGCAGTGGGAGTGGGTGGAGTTTCACCCTCTGGGAAAGGGGCAGGTGACAGGTATTTATCAGTCAGTGCCTCTCTAGCTCTT GTAGGAAGAAGCACACGCAGGATGGAGTCTAGAGGATGAGCGATATTGACTAGCAATTCATGGGCTCCCTCCAGCAGTGCGAGGGTCAGAGTTTCTGGAGCCTTGGGAGGAGGCATCCCTGTGAGGGGGGGTTAGGGAGATGGGAGGGCA CCAGGAAAAGTGATTAGAAGTCAGGTATGGGAAGGCTAAATAGGACAGAGTCGAGTACATCTCTGCTTGGAAAAACATATCAACACCCTTTTTTTTGAACATTATATCTTGCTCATAAAAGAAAACTTTCCACATTGTTTTAACAAACCC CACAGCTGAGAGTCAGGCCTGAATCTTTGATGTGTGCCCATTCACAACGTTGACCCTATTGGTTTGTGGTGGGGCAGGGCATCAAAGACATCATTGACTAATCACATTCCCCTGAATAGCTCATATTTAGAAAATATTCTTAGATTCTAA AAATGTACTATTAATTTGTGATATTCAGTCTTTTAAATATTTTATACATTAAACAGGCATAGTTACAAATATAAAACAAAAATATCCCAAAGCCATTATGCATGGCACTCAAGATTAAAATGGGAAATAATACATCTAATAAATCAAATG TTCCAAGACTTCAAAGGTCTTTTGGAAACAGGCTATGTAAAACAGCACACTGGTTTCAAACTTTGGTAAATTTTAAGAACAACTCTTACAAAGGCATTTAATTCTTATACATAATTTTCAGGGGACCTAAGTTAATCAGCTAATCATGAA GACATGATTTTCATTTTAGAAAACACTTTTGAAAACTTGGGATAATCTCATGCCTTAATGATCAAAGCATTATGAGAAGGACAGTGGTTTTTAACCTGGGCATATGTTCTAACACATTTACTCTCCACTATTCGTACTCTGGTAGCCATG TTAACCCCATCAGAGATTCCTTCTCAAGCCATGTCTCAGAGCTGAGAGGCATCCCAGCAAGTTTTGCAGCTCACAGTTTTTTCCGTAAATTACTTATTCTATAAAATTGGAGTAGGCCATAAACTTTGGAGGGCCCTAGACCAATTTTTT GGATTATTTTTCGTCTTCTATCATTCCGCTGATCTTAGATATTCTCTGCATTAAATATTAAATATCACTTCTAGGCTGAAAAATCCCCCTAAAAATATTTCTAGCTCAGATTTTTCCTCCAAATTCTGCAATAGAAGATCACAATGTGAA CTCTGCATCTCCATGTTAAAGTCTAATGGACATTCACACTTAGCATGTCTCAAAGAAATCTCATGTAAACCATGGCCATCCTGTTCTACCTTAACTTTCTGAGTCTATGGAATGATAATTTCACATCTCATAAACTTGACTGATGTAAGT GTCAAGAAAAGATTGACATTTTGTTAAAAGTTAGTAGTGAAGTGTGTAACGCTTAAGCAAACTTTCATATTTCAAATCTCTTTAGCAAGTGTAACTCTTTTTTCAAGATGTGAAATAATCATTAGGTCAGTCATTTGTAAATAGTACATC TGCTATGGACTTTTTCCAGTTCTTCACCATCCATTTTTATAAAACTCTTATTGTTAAAAAAAAAGTTACTCAGAATTTCATAAAGCCAAACACCTGATTTCAGGAACACTTGAGATGTAAGAAAATTTTATAGGGACCTCCAATCACTAA TTTTCCTATTTTTTCTCTCAAAGAAATGCTGAAGGGAGGAATTCAGGTTGAATGAAAGGAAATAGTAACTTACAGCCATATAGAGTTATAAAGACTTCTTGTAAATGTGAACATATGGTAAAATATAAAAACATGTATTTTTGAAATTTT GGATTCTACTCATTATTTTACTTCAATTTAAGATATAAATGTATAGAAATAAGTATAATTCTAAGCTAATACGTATGCAATGTAGGAAGCTGTAATTACTGACCAAAACTATGTGAAGTGGAGAAAACCTGGGGAAGTGGATGGTTTTAG ATGAAACTGAAGTTAAATTCATATTGATTTAAAGTAAATTGTTATAACTTTATAAAGTTTTTCATCATCACCACAGCAATCACAAAGAGAATAATTATGAATATACGCAAGAGGAAATGAGAAGGGAATCCAAATGTCATTAAAAAAAAA TCACGCCACCTCACAAAATGGTAACAGTGGATATAAAGGATAGAAAGCTATAAACCTGGTAGGAAAACATTGAAAATGGCACAAGTGACTCCTTCCCTGTCACCAATGACAGTCATGTGTTGCATAATGCCTGGGCTATCTTCTGAGAAT GGCTTTGTTAGGCAACTGTGTCATGGTGGGGACATGATAGCATTAGAGAGAATTCTCTCAAACACTGTCATGGCCTTATCAACTATGCTTCTGTAATATTCTGAATCCTTCGCTGCCTTTCCAACAGTGTTTACAACGGTTTCCTAAGAA ATGAAATCCATTTCACCAAACCACTTTTCTTGCTCATCCATAAGAAACACTTCTCCTTTGTTAAAATTACATCATGAGATTGCAAGCATTCAGTAACTTGCAAGCTCCAATTTGAATTCTAGTTGTCTTGCTATTTCCACCACATCTGCA ATTACTTTCTCCACTGAAATCTTGCATTCCTCCAAGTCATCCAGGAGGGTTGAATTCACTTCTTTCAAACTCCTGTTCAAGTAAATGTTTTGCCCTCCTGTCACGAATCATGAATGTTTTTAATGGCATCTAGAATAGTAAATCTTTTTC AGAAGATTTTCAATTTTCTTTTCCCAGGTTCTTCAGACAAGTCACCATGGTAGCTGTAGACTTATGAAATGTATTTCCTGAACCATAAAACAAGAACATCAAAATTACTCTATGATCCATGGGAAACAGAATGCATGTTGTGTTAGCAGG CATGGAAAGAACAGTAATCTCTTTCAACCTCTGTAAGAGAGTTCTTGGTTGATTAGGTACCTTGTCGATAGGCAGTTCTAATTTCAAAGAACTTTTTCTTTTGCTGAGCAGTAAGTCTTAACAGTGGGCTTAAAATATTCAGTAAACCAT TATTTAAGGAGATGTGGCTTAAATATCTAGGCTTTCTTGCTTTATTTATAGAACACTTACAGAGTAGATATAGATTAAATCTTAAGGACCCTAGGATTGTTAGAATAGTAAATGAACATCATATGTTGTAATATAGTTAGCCAGGGAGGG GAAAGATCTCTACAAGAAATAATTTTAAAAACTACTCAAAGAAATCAGAGATATCACAAAATGACAAAACAAGTACAGGGGCAGCAAAAGGTAACAGATGTCAACTATGAGATCTCATCAAGAACTAAGAAAATGGAGAAAAGTACCAGA TGGCAGATGGGAGGCAGTGTGAGCATGCCTCTCCCACTTGGAGATTAGTGTGTAGAGATTTACATTGTGAATTTCTTTTCAAGAACCAATGCAGAGACTTAACAGATATATGAAAAAATTTCACATACACTCTGAAGAAGTCTCAGGCAC AATCCTACTCCATGAAATAAGAAAAAACCATCACATCCCCAGATTCTGAGGGGAGAGAGTTCACTCCAGAGCATACATCCCCACTGGGGATCTGGAAATTCAGGCCACAAGAGAAGGCTTTGATCCTGTGCGGACAAGTGCCTTGAGCAG AATCCACAGGGGAGAGCTGGAAGTGCATGGCAGATATGAGCACAGAAGCTGGGTGTCCAGCCTTGTGGGCAGACCGGGAGGGATGTGGCCTGAAAGCCATGGTTATTATCTCAGCGTGTAAGCTGATGATCTGAGGCTGGTCAGAGTTCT GTGCGCAGACTGCCTGGATGTAAACCTGGCACTGTTAGCAGAGCACTGCATGAATGAAAGGAATGAAAATAGCCTTGCCAACTGCATAGGTGCTGGGTGAGGCTCACTGTGGGGGGCGCACGGCAAGCTATTCAACATTACGTACAGGCA TTTGAGGTCGGGGCATGGAAAAATACTGAGGCAGTGTGTGTATGTTATTTGTGCTGAGAATGAAACTCCTTGACCTTGAAAACAGGACAGGGAGTGGTGTGTGTGCTGTGATAAGGAATGCTGAAAACGGTCTCCTGAGAATGCGGTTTG AGTGCTTTTACAAGGCCACAGGTGTCTCACGACCTGACCTCATAAAGCCATCTAGTGGATGTTTGTGGCTTAACAAGCCCCTTCAATAAGTACTTGGCGGAGGGATGCTGGGGGGACCTTCTTAGAAGAGCTGCGCCCCACCCCCCTCCC TGGACAGCCCAGCTACAATTGTCTGAGAACTCACTGCAAGCTGTAAGCGGCCCACTACTTCCCACTCCCTTTTTTGAACTCTTCTGTGCAGCAGAGGCAATTAAACTCTCCTCTGGAACATTACCCCAGCAGCCTGAGAACCACCCCTTG GCGCTCACAGGGGCTGCAGCCTGCCTTATCCAAGGACAGTTAGAGTGCAGACCCACCTAACCCTGGACCCACTGGTGGTACCCATCCACCCATCCTGGTAGCTTAACACAAAGATACACTTTTAGGAGCTTCATAGCCCCTCTTCCCCCA TTGCCTGAGAAACCACTTTCCCTGGGCAACTTAGGGCAAGCTCAAATCCCACTGCTACCACCACAGCTGGTGCTCTTTTGCAAGTGCCACCTCCTAGCTGGAGACCAACCAGCACAGTCCACACAGCACCTCAAGGAAGAATAAATAGAA CTGTTCCCAGGAAGGAGAAAATGCCTGCATGAGCTCAGCTGTTACCACTGCGTACCACACCCTGACCAGTCAGAGGTCTTGAGTCGGTCCGCATGACAAGTTCACCGCTCGCATAACCAGCATTCAAGAAAGCCAGCACACTAAGCCTAT CTACAGCCAGGGAGTCTCAGAGTCTACGTCACTCCCCTGCCACCTCAATCAGAGCTGGTGCTGGTATCCACTGCTGGGAGACTTGTGCTGAGGTGAAGCCTGGGCTGGATGGCTGGAGGATGAAGAACTGCACGGAGGAGATGGAGGCAC CCAGACAGATGCCCCATGGACATCCTGAAGCAGAGCTGCCTCACTGCCCTGCACACACATGAGAGCGCAGCCAGGAACAGAAGGACTGGGCAACATTCAGGCGGAGCCCAGGCCAATTTTCTAAACATGGAATATGAGTTAAATAAATGG CTTCGTATTAAA >C6orf136_AKR1C1_ENST00000376473_ENST00000477661_30617736_5008105 length=633nt Breakpoint=633nt GCGCGGGACATCTCCGTTTCCCTCCCTCAGCCCCTTCCCCCCCTACCCCCCCGCCCCGGCCTCCTTTCCCCTTCACGAAGCCGGCTCTGGGGCGCGCTCACCCCTGTGAGGAGGCCGGAGGTCGGACTCAGGAGGCTCCTTCTCCACTCC CGGAAGATCATGTACCAGCCCAGCCGGGGTGCGGCCCGGCGTCTCGGCCCTTGCCTGCGCGCCTACCAGGCTCGACCCCAGGACCAGCTTTATCCAGGGACTCTACCATTCCCACCCCTTTGGCCCCACTCCACGACAACCACTTCCCCA TCTTCTCCTCTATTCTGGTCTCCCCTGCCCCCACGCCTTCCCACCCAGCGTCTTCCCCAGGTTCCCCCACTACCTCTCCCTCAGATCCAGGCCCTCAGCTCAGCATGGGTGGTTCTCCCTCCAGGAAAGGGGGAGGAGGGACCAGGACCT GAGTTGCATAGCGGCTGCCTGGATGGGCTTAGAAGCCTTTTTGAGGGACCTCCCTGCCCCTATCCTGGGGCTTGGATACCTTTCCAAGTCCCTGGAACTGCCCACCCTTCCCCTGCCACCCCGTCAGGAGATCCTAGTATGGAGGAACAT CTGTCTGTCATGTATGAGAGACTGAGACAAGAG >C6orf136_AKR1C1_ENST00000528347_ENST00000380859_30617736_5008105 length=798nt Breakpoint=45nt ATGGAGGAACATCTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTG GCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTC TACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATC GGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGCCTAGAGATAATTCCATCTTTTCCTTGAGTCCTGACTGGTGATTCCAGGCCTCCTTGATCAAATTGACT GTCCCCAAATGTTACACACATTTCAGCATTAAAGTTACTACACTTTTCCCAGTAAATTACATTTTTTTGTTTTATTTTATGTTTTAAAACTTAGAGTCAATCAGTGAAGATCTACAGTGGAAATACATATGTATAAAATTAGTGAATTTG GTATAATGATACGGTGCTGTGATAATTTAATAAAAGCATTGAGAAATT >C6orf136_AKR1C1_ENST00000528347_ENST00000380872_30617736_5008105 length=6474nt Breakpoint=45nt ATGGAGGAACATCTGTCTGTCATGTATGAGAGACTGAGACAAGAGGTTCCTAAAAGTAAAGCTTTAGAGGCCACCAAATTGGCAATTGAAGCTGGCTTCCGCCATATTGATTCTGCTCATTTATACAATAATGAGGAGCAGGTTGGACTG GCCATCCGAAGCAAGATTGCAGATGGCAGTGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCATCGACCAGAGTTGGTCCGACCAGCCTTGGAAAGGTCACTGAAAAATCTTCAATTGGATTATGTTGACCTC TACCTTATTCATTTTCCAGTGTCTGTAAAGCCAGGTGAGGAAGTGATCCCAAAAGATGAAAATGGAAAAATACTATTTGACACAGTGGATCTCTGTGCCACATGGGAGGCCGTGGAGAAGTGTAAAGATGCAGGATTGGCCAAGTCCATC GGGGTGTCCAACTTCAACCGCAGGCAGCTGGAGATGATCCTCAACAAGCCAGGGCTCAAGTACAAGCCTGTCTGCAACCAGGTGGAATGTCATCCTTACTTCAACCAGAGAAAACTGCTGGATTTCTGCAAGTCAAAAGACATTGTTCTG GTTGCCTATAGTGCTCTGGGATCCCACCGAGAAGAACCATGGGTGGACCCGAACTCCCCGGTGCTCTTGGAGGACCCAGTCCTTTGTGCCTTGGCAAAAAAGCACAAGCGAACCCCAGCCCTGATTGCCCTGCGCTACCAGCTACAGCGT GGGGTTGTGGTCCTGGCCAAGAGCTACAATGAGCAGCGCATCAGACAGAACGTGCAGGTGTTTGAATTCCAGTTGACTTCAGAGGAGATGAAAGCCATAGATGGCCTAAACAGAAATGTGCGATATTTGACCCTTGATATTTTTGCTGGC CCCCCTAATTATCCATTTTCTGATGAATATTAACATGGAGGGCATTGCATGAGGTCTGCCAGAAGGCCCTGCGTGTGGATGGTGACACAGAGGATGGCTCTATGCTGGTGACTGGACACATCGCCTCTGGTTAAATCTCTCCTGCTTGGT GATTTCAGCAAGCTACAGCAAAGCCCATTGGCCAGAAAGGAAAGACAATAATTTTGTTTTTTCATTTTGAAAAAATTAAATGCTCTCTCCTAAAGATTCTTCACCTACTTTGGTCTCCATAACTTCTATGTTTTCTTTCCTTCTGACACA CTAGTGCCCCTAAATTGTGATTTGCCTATACGTTTAGGGCCGGGGTTGGAAGATGTTAACAACCATTTAAGATTCATTTCTGCAGTGGGAGTGGGTGGAGTTTCACCCTCTGGGAAAGGGGCAGGTGACAGGTATTTATCAGTCAGTGCC TCTCTAGCTCTTGTAGGAAGAAGCACACGCAGGATGGAGTCTAGAGGATGAGCGATATTGACTAGCAATTCATGGGCTCCCTCCAGCAGTGCGAGGGTCAGAGTTTCTGGAGCCTTGGGAGGAGGCATCCCTGTGAGGGGGGGTTAGGGA GATGGGAGGGCACCAGGAAAAGTGATTAGAAGTCAGGTATGGGAAGGCTAAATAGGACAGAGTCGAGTACATCTCTGCTTGGAAAAACATATCAACACCCTTTTTTTTGAACATTATATCTTGCTCATAAAAGAAAACTTTCCACATTGT TTTAACAAACCCCACAGCTGAGAGTCAGGCCTGAATCTTTGATGTGTGCCCATTCACAACGTTGACCCTATTGGTTTGTGGTGGGGCAGGGCATCAAAGACATCATTGACTAATCACATTCCCCTGAATAGCTCATATTTAGAAAATATT CTTAGATTCTAAAAATGTACTATTAATTTGTGATATTCAGTCTTTTAAATATTTTATACATTAAACAGGCATAGTTACAAATATAAAACAAAAATATCCCAAAGCCATTATGCATGGCACTCAAGATTAAAATGGGAAATAATACATCTA ATAAATCAAATGTTCCAAGACTTCAAAGGTCTTTTGGAAACAGGCTATGTAAAACAGCACACTGGTTTCAAACTTTGGTAAATTTTAAGAACAACTCTTACAAAGGCATTTAATTCTTATACATAATTTTCAGGGGACCTAAGTTAATCA GCTAATCATGAAGACATGATTTTCATTTTAGAAAACACTTTTGAAAACTTGGGATAATCTCATGCCTTAATGATCAAAGCATTATGAGAAGGACAGTGGTTTTTAACCTGGGCATATGTTCTAACACATTTACTCTCCACTATTCGTACT CTGGTAGCCATGTTAACCCCATCAGAGATTCCTTCTCAAGCCATGTCTCAGAGCTGAGAGGCATCCCAGCAAGTTTTGCAGCTCACAGTTTTTTCCGTAAATTACTTATTCTATAAAATTGGAGTAGGCCATAAACTTTGGAGGGCCCTA GACCAATTTTTTGGATTATTTTTCGTCTTCTATCATTCCGCTGATCTTAGATATTCTCTGCATTAAATATTAAATATCACTTCTAGGCTGAAAAATCCCCCTAAAAATATTTCTAGCTCAGATTTTTCCTCCAAATTCTGCAATAGAAGA TCACAATGTGAACTCTGCATCTCCATGTTAAAGTCTAATGGACATTCACACTTAGCATGTCTCAAAGAAATCTCATGTAAACCATGGCCATCCTGTTCTACCTTAACTTTCTGAGTCTATGGAATGATAATTTCACATCTCATAAACTTG ACTGATGTAAGTGTCAAGAAAAGATTGACATTTTGTTAAAAGTTAGTAGTGAAGTGTGTAACGCTTAAGCAAACTTTCATATTTCAAATCTCTTTAGCAAGTGTAACTCTTTTTTCAAGATGTGAAATAATCATTAGGTCAGTCATTTGT AAATAGTACATCTGCTATGGACTTTTTCCAGTTCTTCACCATCCATTTTTATAAAACTCTTATTGTTAAAAAAAAAGTTACTCAGAATTTCATAAAGCCAAACACCTGATTTCAGGAACACTTGAGATGTAAGAAAATTTTATAGGGACC TCCAATCACTAATTTTCCTATTTTTTCTCTCAAAGAAATGCTGAAGGGAGGAATTCAGGTTGAATGAAAGGAAATAGTAACTTACAGCCATATAGAGTTATAAAGACTTCTTGTAAATGTGAACATATGGTAAAATATAAAAACATGTAT TTTTGAAATTTTGGATTCTACTCATTATTTTACTTCAATTTAAGATATAAATGTATAGAAATAAGTATAATTCTAAGCTAATACGTATGCAATGTAGGAAGCTGTAATTACTGACCAAAACTATGTGAAGTGGAGAAAACCTGGGGAAGT GGATGGTTTTAGATGAAACTGAAGTTAAATTCATATTGATTTAAAGTAAATTGTTATAACTTTATAAAGTTTTTCATCATCACCACAGCAATCACAAAGAGAATAATTATGAATATACGCAAGAGGAAATGAGAAGGGAATCCAAATGTC ATTAAAAAAAAATCACGCCACCTCACAAAATGGTAACAGTGGATATAAAGGATAGAAAGCTATAAACCTGGTAGGAAAACATTGAAAATGGCACAAGTGACTCCTTCCCTGTCACCAATGACAGTCATGTGTTGCATAATGCCTGGGCTA TCTTCTGAGAATGGCTTTGTTAGGCAACTGTGTCATGGTGGGGACATGATAGCATTAGAGAGAATTCTCTCAAACACTGTCATGGCCTTATCAACTATGCTTCTGTAATATTCTGAATCCTTCGCTGCCTTTCCAACAGTGTTTACAACG GTTTCCTAAGAAATGAAATCCATTTCACCAAACCACTTTTCTTGCTCATCCATAAGAAACACTTCTCCTTTGTTAAAATTACATCATGAGATTGCAAGCATTCAGTAACTTGCAAGCTCCAATTTGAATTCTAGTTGTCTTGCTATTTCC ACCACATCTGCAATTACTTTCTCCACTGAAATCTTGCATTCCTCCAAGTCATCCAGGAGGGTTGAATTCACTTCTTTCAAACTCCTGTTCAAGTAAATGTTTTGCCCTCCTGTCACGAATCATGAATGTTTTTAATGGCATCTAGAATAG TAAATCTTTTTCAGAAGATTTTCAATTTTCTTTTCCCAGGTTCTTCAGACAAGTCACCATGGTAGCTGTAGACTTATGAAATGTATTTCCTGAACCATAAAACAAGAACATCAAAATTACTCTATGATCCATGGGAAACAGAATGCATGT TGTGTTAGCAGGCATGGAAAGAACAGTAATCTCTTTCAACCTCTGTAAGAGAGTTCTTGGTTGATTAGGTACCTTGTCGATAGGCAGTTCTAATTTCAAAGAACTTTTTCTTTTGCTGAGCAGTAAGTCTTAACAGTGGGCTTAAAATAT TCAGTAAACCATTATTTAAGGAGATGTGGCTTAAATATCTAGGCTTTCTTGCTTTATTTATAGAACACTTACAGAGTAGATATAGATTAAATCTTAAGGACCCTAGGATTGTTAGAATAGTAAATGAACATCATATGTTGTAATATAGTT AGCCAGGGAGGGGAAAGATCTCTACAAGAAATAATTTTAAAAACTACTCAAAGAAATCAGAGATATCACAAAATGACAAAACAAGTACAGGGGCAGCAAAAGGTAACAGATGTCAACTATGAGATCTCATCAAGAACTAAGAAAATGGAG AAAAGTACCAGATGGCAGATGGGAGGCAGTGTGAGCATGCCTCTCCCACTTGGAGATTAGTGTGTAGAGATTTACATTGTGAATTTCTTTTCAAGAACCAATGCAGAGACTTAACAGATATATGAAAAAATTTCACATACACTCTGAAGA AGTCTCAGGCACAATCCTACTCCATGAAATAAGAAAAAACCATCACATCCCCAGATTCTGAGGGGAGAGAGTTCACTCCAGAGCATACATCCCCACTGGGGATCTGGAAATTCAGGCCACAAGAGAAGGCTTTGATCCTGTGCGGACAAG TGCCTTGAGCAGAATCCACAGGGGAGAGCTGGAAGTGCATGGCAGATATGAGCACAGAAGCTGGGTGTCCAGCCTTGTGGGCAGACCGGGAGGGATGTGGCCTGAAAGCCATGGTTATTATCTCAGCGTGTAAGCTGATGATCTGAGGCT GGTCAGAGTTCTGTGCGCAGACTGCCTGGATGTAAACCTGGCACTGTTAGCAGAGCACTGCATGAATGAAAGGAATGAAAATAGCCTTGCCAACTGCATAGGTGCTGGGTGAGGCTCACTGTGGGGGGCGCACGGCAAGCTATTCAACAT TACGTACAGGCATTTGAGGTCGGGGCATGGAAAAATACTGAGGCAGTGTGTGTATGTTATTTGTGCTGAGAATGAAACTCCTTGACCTTGAAAACAGGACAGGGAGTGGTGTGTGTGCTGTGATAAGGAATGCTGAAAACGGTCTCCTGA GAATGCGGTTTGAGTGCTTTTACAAGGCCACAGGTGTCTCACGACCTGACCTCATAAAGCCATCTAGTGGATGTTTGTGGCTTAACAAGCCCCTTCAATAAGTACTTGGCGGAGGGATGCTGGGGGGACCTTCTTAGAAGAGCTGCGCCC CACCCCCCTCCCTGGACAGCCCAGCTACAATTGTCTGAGAACTCACTGCAAGCTGTAAGCGGCCCACTACTTCCCACTCCCTTTTTTGAACTCTTCTGTGCAGCAGAGGCAATTAAACTCTCCTCTGGAACATTACCCCAGCAGCCTGAG AACCACCCCTTGGCGCTCACAGGGGCTGCAGCCTGCCTTATCCAAGGACAGTTAGAGTGCAGACCCACCTAACCCTGGACCCACTGGTGGTACCCATCCACCCATCCTGGTAGCTTAACACAAAGATACACTTTTAGGAGCTTCATAGCC CCTCTTCCCCCATTGCCTGAGAAACCACTTTCCCTGGGCAACTTAGGGCAAGCTCAAATCCCACTGCTACCACCACAGCTGGTGCTCTTTTGCAAGTGCCACCTCCTAGCTGGAGACCAACCAGCACAGTCCACACAGCACCTCAAGGAA GAATAAATAGAACTGTTCCCAGGAAGGAGAAAATGCCTGCATGAGCTCAGCTGTTACCACTGCGTACCACACCCTGACCAGTCAGAGGTCTTGAGTCGGTCCGCATGACAAGTTCACCGCTCGCATAACCAGCATTCAAGAAAGCCAGCA CACTAAGCCTATCTACAGCCAGGGAGTCTCAGAGTCTACGTCACTCCCCTGCCACCTCAATCAGAGCTGGTGCTGGTATCCACTGCTGGGAGACTTGTGCTGAGGTGAAGCCTGGGCTGGATGGCTGGAGGATGAAGAACTGCACGGAGG AGATGGAGGCACCCAGACAGATGCCCCATGGACATCCTGAAGCAGAGCTGCCTCACTGCCCTGCACACACATGAGAGCGCAGCCAGGAACAGAAGGACTGGGCAACATTCAGGCGGAGCCCAGGCCAATTTTCTAAACATGGAATATGAG TTAAATAAATGGCTTCGTATTAAA >C6orf136_AKR1C1_ENST00000528347_ENST00000477661_30617736_5008105 length=45nt Breakpoint=45nt ATGGAGGAACATCTGTCTGTCATGTATGAGAGACTGAGACAAGAG |
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Fusion Protein Sequence for C6orf136_AKR1C1 |
| In-frame Fusion Protein Sequences. |
>C6orf136_AKR1C1_ENST00000293604_ENST00000434459_30617736_5008105 length=358nt MVVKRRGSGCPVPAMEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQFGHVNMVMVRSLEP QEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDPMDWSPSNVQKWLLWTEHQYRLPPMGKAFQELAGKELCAMSEEQFRQRSPLGGDVLHAHLDIWKSASTSEESWTDSEVDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKG IFKIEDSAQVARLWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQFVHPI >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105 length=634nt MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105 length=453nt MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for C6orf136_AKR1C1 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.L241H_634_L552H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVHCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R66Q_634_R377Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIQSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.G264R_634_G575R length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRRVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.C188G_634_C499G length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVGNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.A37D_634_A348D length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEDTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.E224K_634_E535K length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRKEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.A44T_634_A355T length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIETGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.C188R_634_C499R length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVRNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R91G_634_R402G length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHGPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.F197L_634_F508L length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.L40F_634_L351F length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKFAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V120E_634_V431E length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPESVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.K68N_634_K379N length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSNIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Y216C_634_Y527C length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVACSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.E174Q_634_E485Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLQMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V265I_634_V576I length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGIVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Q190R_634_Q501R length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNRVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Y55C_634_Y366C length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLCNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.L106I_634_L417I length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNIQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.A160V_634_A471V length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.D204Y_634_D515Y length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLYFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V128M_634_V439M length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEMIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R250Q_634_R561Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.D156Y_634_D467Y length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKYAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Y110H_634_Y421H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDHVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V234A_634_V545A length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPALLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.E274K_634_E585K length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNKQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.S102L_634_S413L length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERLLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R263C_634_R574C length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQCGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.I49V_634_I360V length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHVDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R276C_634_R587C length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQCIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.L182R_634_L493R length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGRKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Q260K_634_Q571K length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYKLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.K33T_634_K344T length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSTALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V151M_634_V462M length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R47H_634_R358H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.F80L;p.L203M;p.L241I_634_F391L;L514M;L552I length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDILYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLMDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVICALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.Y110H_634_Y421H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDHVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.D78H_634_D389H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREHIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.E36Q_634_E347Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALQATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.S89F_634_S400F length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNFHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.A245T_634_A556T length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALTKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.L94V_634_L405V length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPEVVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.S121Y_634_S432Y length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVYVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R223Q_634_R534Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHQEEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R250Q_634_R561Q length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.A253V_634_A564V length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPVLIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.K123N_634_K434N length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVNPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.R258H_634_R569H length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALHYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.V228M_634_V539M length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWMDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.H248Y_634_H559Y length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKYKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000376473_ENST00000434459_30617736_5008105_3-gene_p.G125D_634_G436D length=634AA MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQT RPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPDEEVIPKDENGKILF DTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT SEEMKAIDGLNRNVRYLTLDIFAGPPNYPFSDEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.L241H_453_L371H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVHCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R66Q_453_R196Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIQSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.G264R_453_G394R length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRRVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.C188G_453_C318G length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVGNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.A37D_453_A167D length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEDTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.E224K_453_E354K length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHRKEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.A44T_453_A174T length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIETGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.C188R_453_C318R length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVRNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R91G_453_R221G length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHGPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.F197L_453_F327L length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.L40F_453_L170F length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKFAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V120E_453_V250E length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPESVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_5-gene_p.G7C_453_G7C length=453AA MYQPSRCAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.K68N_453_K198N length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSNIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Y216C_453_Y346C length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVACSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.E174Q_453_E304Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLQMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V265I_453_V395I length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGIVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Q190R_453_Q320R length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNRVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Y55C_453_Y185C length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLCNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.L106I_453_L236I length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNIQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.A160V_453_A290V length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLVKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.D204Y_453_D334Y length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLYFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V128M_453_V258M length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEMIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R250Q_453_R380Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.D156Y_453_D286Y length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKYAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Y110H_453_Y240H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDHVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V234A_453_V364A length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPALLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.E274K_453_E404K length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNKQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.S102L_453_S232L length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERLLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R263C_453_R393C length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQCGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.I49V_453_I179V length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHVDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R276C_453_R406C length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQCIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.L182R_453_L312R length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGRKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Q260K_453_Q390K length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYKLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.K33T_453_K163T length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSTALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V151M_453_V281M length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R47H_453_R177H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFHHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.F80L;p.L203M;p.L241I_453_F210L;L333M;L371I length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDILYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLMDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVICALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.Y110H_453_Y240H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDHVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.D78H_453_D208H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREHIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.E36Q_453_E166Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALQATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.S89F_453_S219F length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNFHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.A245T_453_A375T length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALTKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.L94V_453_L224V length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPEVVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.S121Y_453_S251Y length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVYVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R223Q_453_R353Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHQEEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R250Q_453_R380Q length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.A253V_453_A383V length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPVLIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.K123N_453_K253N length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVNPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.R258H_453_R388H length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALHYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.V228M_453_V358M length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWMDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.H248Y_453_H378Y length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKYKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_3-gene_p.G125D_453_G255D length=453AA MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPDEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY >C6orf136_AKR1C1_ENST00000528347_ENST00000434459_30617736_5008105_5-gene_p.Q20L_453_Q20L length=453AA MYQPSRGAARRLGPCLRAYLARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSV MYERLRQEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNR RQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAGPPNYPFS DEY |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-06-2557-01A | 3-gene | p.L241H | 634 | L552H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-06-5416-01A | 3-gene | p.R66Q | 634 | R377Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-12-0775-01A | 3-gene | p.G264R | 634 | G575R |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-13-0920-01A | 3-gene | p.C188G | 634 | C499G |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-13-1495-01A | 3-gene | p.A37D | 634 | A348D |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-22-4596-01A | 3-gene | p.E224K | 634 | E535K |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-24-2289-01A | 3-gene | p.A44T | 634 | A355T |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-28-1755-01A | 3-gene | p.C188R | 634 | C499R |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-37-4130-01A | 3-gene | p.R91G | 634 | R402G |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-53-7626-01A | 3-gene | p.F197L | 634 | F508L |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-5P-A9JV-01A | 3-gene | p.L40F | 634 | L351F |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-77-8008-01A | 3-gene | p.V120E | 634 | V431E |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-78-7156-01A | 3-gene | p.K68N | 634 | K379N |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-91-6835-01A | 3-gene | p.Y216C | 634 | Y527C |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-A1-A0SI-01A | 3-gene | p.E174Q | 634 | E485Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-A5-A0G2-01A | 3-gene | p.V265I | 634 | V576I |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AB-2808-03B | 3-gene | p.Q190R | 634 | Q501R |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AD-6964-01A | 3-gene | p.Y55C | 634 | Y366C |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AG-3892-01A | 3-gene | p.L106I | 634 | L417I |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AP-A0LM-01A | 3-gene | p.A160V | 634 | A471V |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AP-A1E0-01A | 3-gene | p.D204Y | 634 | D515Y |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AR-A1AK-01A | 3-gene | p.V128M | 634 | V439M |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-AX-A063-01A | 3-gene | p.R250Q | 634 | R561Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-B0-5092-01A | 3-gene | p.D156Y | 634 | D467Y |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-B5-A3FC-01A | 3-gene | p.Y110H | 634 | Y421H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-BG-A2L7-01A | 3-gene | p.V234A | 634 | V545A |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-BH-A0HP-01A | 3-gene | p.E274K | 634 | E585K |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-BH-A18G-01A | 3-gene | p.S102L | 634 | S413L |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-BS-A0UV-01A | 3-gene | p.R263C | 634 | R574C |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-CD-8531-01A | 3-gene | p.I49V | 634 | I360V |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-CK-5913-01A | 3-gene | p.R276C | 634 | R587C |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-D1-A17Q-01A | 3-gene | p.L182R | 634 | L493R |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-D3-A2JC-06A | 3-gene | p.Q260K | 634 | Q571K |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-D7-8579-01A | 3-gene | p.K33T | 634 | K344T |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-DS-A1OD-01A | 3-gene | p.V151M | 634 | V462M |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-DU-A5TT-01A | 3-gene | p.R47H | 634 | R358H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-E6-A1LX-01A | 3-gene | p.F80L;p.L203M;p.L241I | 634 | F391L;L514M;L552I |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-E6-A1M0-01A | 3-gene | p.Y110H | 634 | Y421H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-E7-A5KE-01A | 3-gene | p.D78H | 634 | D389H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-EA-A78R-01A | 3-gene | p.E36Q | 634 | E347Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-EB-A3XF-01A | 3-gene | p.S89F | 634 | S400F |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-EB-A5SE-01A | 3-gene | p.A245T | 634 | A556T |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-EE-A2MQ-06A | 3-gene | p.L94V | 634 | L405V |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-EO-A3B0-01A | 3-gene | p.S121Y | 634 | S432Y |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-F7-A624-01A | 3-gene | p.R223Q | 634 | R534Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-FW-A3R5-06A | 3-gene | p.R250Q | 634 | R561Q |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-G4-6588-01A | 3-gene | p.A253V | 634 | A564V |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-GN-A26C-01A | 3-gene | p.K123N | 634 | K434N |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-GU-A762-01A | 3-gene | p.R258H | 634 | R569H |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-HU-A4GX-01A | 3-gene | p.V228M | 634 | V539M |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-IB-7651-01A | 3-gene | p.H248Y | 634 | H559Y |
| ENST00000376473_ENST00000434459_30617736_5008105 | TCGA-KN-8427-01A | 3-gene | p.G125D | 634 | G436D |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-06-2557-01A | 3-gene | p.L241H | 453 | L371H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-06-5416-01A | 3-gene | p.R66Q | 453 | R196Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-12-0775-01A | 3-gene | p.G264R | 453 | G394R |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-13-0920-01A | 3-gene | p.C188G | 453 | C318G |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-13-1495-01A | 3-gene | p.A37D | 453 | A167D |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-22-4596-01A | 3-gene | p.E224K | 453 | E354K |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-24-2289-01A | 3-gene | p.A44T | 453 | A174T |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-28-1755-01A | 3-gene | p.C188R | 453 | C318R |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-37-4130-01A | 3-gene | p.R91G | 453 | R221G |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-53-7626-01A | 3-gene | p.F197L | 453 | F327L |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-5P-A9JV-01A | 3-gene | p.L40F | 453 | L170F |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-77-8008-01A | 3-gene | p.V120E | 453 | V250E |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-77-8130-01A | 5-gene | p.G7C | 453 | G7C |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-78-7156-01A | 3-gene | p.K68N | 453 | K198N |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-91-6835-01A | 3-gene | p.Y216C | 453 | Y346C |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-A1-A0SI-01A | 3-gene | p.E174Q | 453 | E304Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-A5-A0G2-01A | 3-gene | p.V265I | 453 | V395I |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AB-2808-03B | 3-gene | p.Q190R | 453 | Q320R |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AD-6964-01A | 3-gene | p.Y55C | 453 | Y185C |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AG-3892-01A | 3-gene | p.L106I | 453 | L236I |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AP-A0LM-01A | 3-gene | p.A160V | 453 | A290V |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AP-A1E0-01A | 3-gene | p.D204Y | 453 | D334Y |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AR-A1AK-01A | 3-gene | p.V128M | 453 | V258M |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-AX-A063-01A | 3-gene | p.R250Q | 453 | R380Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-B0-5092-01A | 3-gene | p.D156Y | 453 | D286Y |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-B5-A3FC-01A | 3-gene | p.Y110H | 453 | Y240H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-BG-A2L7-01A | 3-gene | p.V234A | 453 | V364A |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-BH-A0HP-01A | 3-gene | p.E274K | 453 | E404K |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-BH-A18G-01A | 3-gene | p.S102L | 453 | S232L |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-BS-A0UV-01A | 3-gene | p.R263C | 453 | R393C |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-CD-8531-01A | 3-gene | p.I49V | 453 | I179V |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-CK-5913-01A | 3-gene | p.R276C | 453 | R406C |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-D1-A17Q-01A | 3-gene | p.L182R | 453 | L312R |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-D3-A2JC-06A | 3-gene | p.Q260K | 453 | Q390K |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-D7-8579-01A | 3-gene | p.K33T | 453 | K163T |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-DS-A1OD-01A | 3-gene | p.V151M | 453 | V281M |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-DU-A5TT-01A | 3-gene | p.R47H | 453 | R177H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-E6-A1LX-01A | 3-gene | p.F80L;p.L203M;p.L241I | 453 | F210L;L333M;L371I |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-E6-A1M0-01A | 3-gene | p.Y110H | 453 | Y240H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-E7-A5KE-01A | 3-gene | p.D78H | 453 | D208H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-EA-A78R-01A | 3-gene | p.E36Q | 453 | E166Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-EB-A3XF-01A | 3-gene | p.S89F | 453 | S219F |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-EB-A5SE-01A | 3-gene | p.A245T | 453 | A375T |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-EE-A2MQ-06A | 3-gene | p.L94V | 453 | L224V |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-EO-A3B0-01A | 3-gene | p.S121Y | 453 | S251Y |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-F7-A624-01A | 3-gene | p.R223Q | 453 | R353Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-FW-A3R5-06A | 3-gene | p.R250Q | 453 | R380Q |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-G4-6588-01A | 3-gene | p.A253V | 453 | A383V |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-GN-A26C-01A | 3-gene | p.K123N | 453 | K253N |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-GU-A762-01A | 3-gene | p.R258H | 453 | R388H |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-HU-A4GX-01A | 3-gene | p.V228M | 453 | V358M |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-IB-7651-01A | 3-gene | p.H248Y | 453 | H378Y |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-KN-8427-01A | 3-gene | p.G125D | 453 | G255D |
| ENST00000528347_ENST00000434459_30617736_5008105 | TCGA-LN-A9FP-01A | 5-gene | p.Q20L | 453 | Q20L |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
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Fusion Gene Exprssed Samples for C6orf136_AKR1C1 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | BLCA | TCGA-FD-A43N-01A | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 30617736 | + | |
| WashU | BLCA | TCGA-FD-A43N-01A | C6orf136 | chr6 | 30617736 | + | AKR1C1 | chr10 | 5008106 | + | |
| cBioPortal | BLCA_TCGA_PAN_CAN_ATLAS_2018 | BLCA | TCGA-FD-A43N-01 | C6ORF136 | chr6 | 30649959 | AKR1C1 | chr10 | 4965914 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
Top |
Related Drugs for C6orf136_AKR1C1 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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