Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:TPX2-EYS (FusionGDB2 ID:HG22974TG346007)

Fusion Gene Summary for TPX2-EYS

check button Fusion gene summary
Fusion gene informationFusion gene name: TPX2-EYS
Fusion gene ID: hg22974tg346007
HgeneTgene
Gene symbol

TPX2

EYS

Gene ID

22974

346007

Gene nameTPX2 microtubule nucleation factoreyes shut homolog
SynonymsC20orf1|C20orf2|DIL-2|DIL2|FLS353|GD:C20orf1|HCA519|HCTP4|REPP86|p100C6orf178|C6orf179|C6orf180|EGFL10|EGFL11|RP25|SPAM|bA166P24.2|bA307F22.3|bA74E24.1|dJ1018A4.2|dJ22I17.2|dJ303F19.1
Cytomap('TPX2')('EYS')

20q11.21

6q12

Type of geneprotein-codingprotein-coding
Descriptiontargeting protein for Xklp2TPX2, microtubule-associated protein homologTPX2, microtubule-associated, homologdifferentially expressed in cancerous and non-cancerous lung cells 2differentially expressed in lung cellshepatocellular carcinoma-associated protein eyes shut homologEGF-like-domain, multiple 10EGF-like-domain, multiple 11epidermal growth factor-like protein 10epidermal growth factor-like protein 11protein spacemaker homolog
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000300403, ENST00000340513, 
Fusion gene scores* DoF score21 X 15 X 15=472536 X 24 X 15=12960
# samples 4038
** MAII scorelog2(40/4725*10)=-3.56224242422107
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(38/12960*10)=-5.09192248944104
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TPX2 [Title/Abstract] AND EYS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTPX2(30347982)-EYS(64791895), # samples:2
Anticipated loss of major functional domain due to fusion event.TPX2-EYS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TPX2-EYS seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TPX2-EYS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TPX2-EYS seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTPX2

GO:0007020

microtubule nucleation

26414402

HgeneTPX2

GO:0007026

negative regulation of microtubule depolymerization

26414402

HgeneTPX2

GO:0032147

activation of protein kinase activity

14580337|19801554

HgeneTPX2

GO:0090307

mitotic spindle assembly

26165940


check buttonFusion gene breakpoints across TPX2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across EYS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-60-2706-01ATPX2chr20

30347982

-EYSchr6

64791895

-
ChimerDB4LUSCTCGA-60-2706-01ATPX2chr20

30347982

+EYSchr6

64791895

-


Top

Fusion Gene ORF analysis for TPX2-EYS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000300403ENST00000342421TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000300403ENST00000370618TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000300403ENST00000393380TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000300403ENST00000486069TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000340513ENST00000342421TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000340513ENST00000370618TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000340513ENST00000393380TPX2chr20

30347982

+EYSchr6

64791895

-
5CDS-intronENST00000340513ENST00000486069TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000300403ENST00000370616TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000300403ENST00000370621TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000300403ENST00000503581TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000340513ENST00000370616TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000340513ENST00000370621TPX2chr20

30347982

+EYSchr6

64791895

-
In-frameENST00000340513ENST00000503581TPX2chr20

30347982

+EYSchr6

64791895

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000340513TPX2chr2030347982+ENST00000503581EYSchr664791895-438475750137671088
ENST00000340513TPX2chr2030347982+ENST00000370621EYSchr664791895-429175750138301109
ENST00000340513TPX2chr2030347982+ENST00000370616EYSchr664791895-383175750138301109
ENST00000300403TPX2chr2030347982+ENST00000503581EYSchr664791895-438475750137671088
ENST00000300403TPX2chr2030347982+ENST00000370621EYSchr664791895-429175750138301109
ENST00000300403TPX2chr2030347982+ENST00000370616EYSchr664791895-383175750138301109

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000340513ENST00000503581TPX2chr2030347982+EYSchr664791895-0.0001902060.9998098
ENST00000340513ENST00000370621TPX2chr2030347982+EYSchr664791895-0.0003796580.9996203
ENST00000340513ENST00000370616TPX2chr2030347982+EYSchr664791895-0.0006673020.9993327
ENST00000300403ENST00000503581TPX2chr2030347982+EYSchr664791895-0.0001902060.9998098
ENST00000300403ENST00000370621TPX2chr2030347982+EYSchr664791895-0.0003796580.9996203
ENST00000300403ENST00000370616TPX2chr2030347982+EYSchr664791895-0.0006673020.9993327

Top

Fusion Genomic Features for TPX2-EYS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for TPX2-EYS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:30347982/chr6:64791895)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091004_10400595.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091042_10770595.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091079_11150595.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091117_11590595.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091161_11970595.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109170_2120595.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST00000342421091883_20630595.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092099_21400595.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109213_2540595.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092145_23390595.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092335_23680595.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092371_24080595.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092419_26090595.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109256_2920595.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092610_26460595.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092648_26890595.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092717_28950595.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092896_29320595.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092933_29700595.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST00000342421092975_31650595.0DomainLaminin G-like 5
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109332_3680595.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109370_4060595.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109567_6020595.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109643_6790595.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109681_7200595.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109733_7690595.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109771_8070595.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109809_8470595.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109849_8880595.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109890_9260595.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109928_9640595.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000034242109966_10020595.0DomainEGF-like 15
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412145_233921413166.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412335_236821413166.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412371_240821413166.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412419_260921413166.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412610_264621413166.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412648_268921413166.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412717_289521413166.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412896_293221413166.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412933_297021413166.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412975_316521413166.0DomainLaminin G-like 5
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111004_10400595.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111042_10770595.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111079_11150595.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111117_11590595.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111161_11970595.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011170_2120595.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST000003706180111883_20630595.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112099_21400595.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011213_2540595.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112145_23390595.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112335_23680595.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112371_24080595.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112419_26090595.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011256_2920595.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112610_26460595.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112648_26890595.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112717_28950595.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112896_29320595.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112933_29700595.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST000003706180112975_31650595.0DomainLaminin G-like 5
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011332_3680595.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011370_4060595.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011567_6020595.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011643_6790595.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011681_7200595.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011733_7690595.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011771_8070595.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011809_8470595.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011849_8880595.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011890_9260595.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011928_9640595.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000370618011966_10020595.0DomainEGF-like 15
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442145_233921413166.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442335_236821413166.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442371_240821413166.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442419_260921413166.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442610_264621413166.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442648_268921413166.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442717_289521413166.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442896_293221413166.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442933_297021413166.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442975_316521413166.0DomainLaminin G-like 5
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121004_10400620.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121042_10770620.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121079_11150620.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121117_11590620.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121161_11970620.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012170_2120620.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST000003933800121883_20630620.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122099_21400620.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012213_2540620.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122145_23390620.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122335_23680620.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122371_24080620.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122419_26090620.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012256_2920620.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122610_26460620.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122648_26890620.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122717_28950620.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122896_29320620.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122933_29700620.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST000003933800122975_31650620.0DomainLaminin G-like 5
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012332_3680620.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012370_4060620.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012567_6020620.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012643_6790620.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012681_7200620.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012733_7690620.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012771_8070620.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012809_8470620.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012849_8880620.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012890_9260620.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012928_9640620.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST00000393380012966_10020620.0DomainEGF-like 15
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432145_233921413145.0DomainLaminin G-like 2
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432335_236821413145.0DomainEGF-like 22
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432371_240821413145.0DomainEGF-like 23
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432419_260921413145.0DomainLaminin G-like 3
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432610_264621413145.0DomainEGF-like 24
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432648_268921413145.0DomainEGF-like 25
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432717_289521413145.0DomainLaminin G-like 4
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432896_293221413145.0DomainEGF-like 26
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432933_297021413145.0DomainEGF-like 27
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432975_316521413145.0DomainLaminin G-like 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411004_104021413166.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411042_107721413166.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411079_111521413166.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411117_115921413166.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411161_119721413166.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741170_21221413166.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627411883_206321413166.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000037061627412099_214021413166.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741213_25421413166.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741256_29221413166.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741332_36821413166.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741370_40621413166.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741567_60221413166.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741643_67921413166.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741681_72021413166.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741733_76921413166.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741771_80721413166.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741809_84721413166.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741849_88821413166.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741890_92621413166.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741928_96421413166.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706162741966_100221413166.0DomainEGF-like 15
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441004_104021413166.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441042_107721413166.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441079_111521413166.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441117_115921413166.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441161_119721413166.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044170_21221413166.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130441883_206321413166.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000037062130442099_214021413166.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044213_25421413166.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044256_29221413166.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044332_36821413166.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044370_40621413166.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044567_60221413166.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044643_67921413166.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044681_72021413166.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044733_76921413166.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044771_80721413166.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044809_84721413166.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044849_88821413166.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044890_92621413166.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044928_96421413166.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000003706213044966_100221413166.0DomainEGF-like 15
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431004_104021413145.0DomainEGF-like 16%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431042_107721413145.0DomainEGF-like 17
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431079_111521413145.0DomainEGF-like 18
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431117_115921413145.0DomainEGF-like 19
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431161_119721413145.0DomainEGF-like 20%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043170_21221413145.0DomainEGF-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130431883_206321413145.0DomainLaminin G-like 1
TgeneEYSchr20:30347982chr6:64791895ENST0000050358130432099_214021413145.0DomainEGF-like 21
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043213_25421413145.0DomainEGF-like 2
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043256_29221413145.0DomainEGF-like 3
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043332_36821413145.0DomainEGF-like 4
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043370_40621413145.0DomainEGF-like 5
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043567_60221413145.0DomainEGF-like 6
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043643_67921413145.0DomainEGF-like 7
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043681_72021413145.0DomainEGF-like 8%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043733_76921413145.0DomainEGF-like 9%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043771_80721413145.0DomainEGF-like 10%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043809_84721413145.0DomainEGF-like 11
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043849_88821413145.0DomainEGF-like 12
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043890_92621413145.0DomainEGF-like 13
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043928_96421413145.0DomainEGF-like 14%3B calcium-binding
TgeneEYSchr20:30347982chr6:64791895ENST000005035813043966_100221413145.0DomainEGF-like 15


Top

Fusion Gene Sequence for TPX2-EYS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>93557_93557_1_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000370616_length(transcript)=3831nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCACTTATCCTCATTGTGATCTTGGAA
AAGCCAAAACCAGCAGAACGGAAAGTGAAGAAGGAGGCTTTATCCATAAGTGATCCATCTTTCAGAAGCAATGAGTTATCCTGGATGTCT
TTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCAGATGGTATCCTATTTTATGCTGCACAA
CACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTTCGCTACAACCTTGGCGACAGAACTATC
ATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGAAGAGTTGGTGCAGAAGGCTACCTGGAT
CTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACAGACTTCTATATTGGAGGAGTATCTTCT
TTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGACAAGTTATCATAAATAATCAAGAATTA
CAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGTGGGTACAACACATGCAGAAATGGAGGT
GAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACATGTAACCAGTCTGTGTCCTGTTTGAAT
AATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGTACTTTGGGTTGGGTGGGAAGGTATTGT
GAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGATCCAAATTATAGAATGAGAAACCTCCAG
TTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGAATAGCTCAAAATGAAGAAAATGATTTT
CTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCTGTGCCTATGAGCTATAACAATGGCACA
TTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTACATAAATAACAGTCTAATTCTTTCCGAG
GATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGCTTTGAATATGGTAGAAAGGTAAATATC
GTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAGGAACCAAAAAACATTGAACTAATTAAA

>93557_93557_1_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000370616_length(amino acids)=1109AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS
SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQ
GCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSY
SCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLG
ERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDV

--------------------------------------------------------------
>93557_93557_2_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000370621_length(transcript)=4291nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCACTTATCCTCATTGTGATCTTGGAA
AAGCCAAAACCAGCAGAACGGAAAGTGAAGAAGGAGGCTTTATCCATAAGTGATCCATCTTTCAGAAGCAATGAGTTATCCTGGATGTCT
TTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCAGATGGTATCCTATTTTATGCTGCACAA
CACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTTCGCTACAACCTTGGCGACAGAACTATC
ATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGAAGAGTTGGTGCAGAAGGCTACCTGGAT
CTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACAGACTTCTATATTGGAGGAGTATCTTCT
TTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGACAAGTTATCATAAATAATCAAGAATTA
CAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGTGGGTACAACACATGCAGAAATGGAGGT
GAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACATGTAACCAGTCTGTGTCCTGTTTGAAT
AATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGTACTTTGGGTTGGGTGGGAAGGTATTGT
GAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGATCCAAATTATAGAATGAGAAACCTCCAG
TTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGAATAGCTCAAAATGAAGAAAATGATTTT
CTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCTGTGCCTATGAGCTATAACAATGGCACA
TTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTACATAAATAACAGTCTAATTCTTTCCGAG
GATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGCTTTGAATATGGTAGAAAGGTAAATATC
GTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAGGAACCAAAAAACATTGAACTAATTAAA
TTAGAAGGATACAATGTTTATGATGGAGATGAACAAAATGAGGTTACATAAGTTAACACTAGAGATTTTAGTACACACTATACATAAATG
CAGTTATTTTGATAGTTATTTCTTTGATACATTGCTTACGGGGAATCAACTGTTTACTATATTACCTGAAATAGTCTAAATGCTAACATA
TCTTTTTGATAAGATTGTAAAATGTCACTGAAGGTTCTGATTGTTTTTCCTACATCTAATTTATCTGTATATATTTTGATTCATGTTTTA
ACTCCATTAGTTCAGTGCTTATTCACAGAATGTGCTTATTCACTTTGCTTATTCACTTTTTACCTATCCCTAATGCTTACATTTTAAAAT
CAACGTGTAAACACAATTTTAAAAATCAATGTGTAAGCTGAACTTTAAAATGTTTAAAATTCAGTTGGGAATGAATTAGGGATAGGTACA

>93557_93557_2_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000370621_length(amino acids)=1109AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS
SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQ
GCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSY
SCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLG
ERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDV

--------------------------------------------------------------
>93557_93557_3_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000503581_length(transcript)=4384nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCTTTATCCATAAGTGATCCATCTTTC
AGAAGCAATGAGTTATCCTGGATGTCTTTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCA
GATGGTATCCTATTTTATGCTGCACAACACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTT
CGCTACAACCTTGGCGACAGAACTATCATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGA
AGAGTTGGTGCAGAAGGCTACCTGGATCTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACA
GACTTCTATATTGGAGGAGTATCTTCTTTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGA
CAAGTTATCATAAATAATCAAGAATTACAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGT
GGGTACAACACATGCAGAAATGGAGGTGAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACA
TGTAACCAGTCTGTGTCCTGTTTGAATAATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGT
ACTTTGGGTTGGGTGGGAAGGTATTGTGAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGAT
CCAAATTATAGAATGAGAAACCTCCAGTTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGA
ATAGCTCAAAATGAAGAAAATGATTTTCTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCT
GTGCCTATGAGCTATAACAATGGCACATTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTAC
ATAAATAACAGTCTAATTCTTTCCGAGGATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGC
TTTGAATATGGTAGAAAGGTAAATATCGTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAG
GAACCAAAAAACATTGAACTAATTAAATTAGAAGGATACAATGTTTATGATGGAGATGAACAAAATGAGGTTACATAAGTTAACACTAGA
GATTTTAGTACACACTATACATAAATGCAGTTATTTTGATAGTTATTTCTTTGATACATTGCTTACGGGGAATCAACTGTTTACTATATT
ACCTGAAATAGTCTAAATGCTAACATATCTTTTTGATAAGATTGTAAAATGTCACTGAAGGTTCTGATTGTTTTTCCTACATCTAATTTA
TCTGTATATATTTTGATTCATGTTTTAACTCCATTAGTTCAGTGCTTATTCACAGAATGTGCTTATTCACTTTGCTTATTCACTTTTTAC
CTATCCCTAATGCTTACATTTTAAAATCAACGTGTAAACACAATTTTAAAAATCAATGTGTAAGCTGAACTTTAAAATGTTTAAAATTCA
GTTGGGAATGAATTAGGGATAGGTACAAATAAGAAAAAAATCAAGTTATTAATCAAAGGAAAAATAAAAATTATACAAAGCAATGTAACC
ATATTGTATTACATGGCTTAGCTACAACTTATTTATATGATTCAACAATGTAAAACTTGAACATAGATTTAAACCAAAAATTATTGCATG

>93557_93557_3_TPX2-EYS_TPX2_chr20_30347982_ENST00000300403_EYS_chr6_64791895_ENST00000503581_length(amino acids)=1088AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKV
TINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAK
GGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFST
AKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHH
VVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVYD

--------------------------------------------------------------
>93557_93557_4_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000370616_length(transcript)=3831nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCACTTATCCTCATTGTGATCTTGGAA
AAGCCAAAACCAGCAGAACGGAAAGTGAAGAAGGAGGCTTTATCCATAAGTGATCCATCTTTCAGAAGCAATGAGTTATCCTGGATGTCT
TTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCAGATGGTATCCTATTTTATGCTGCACAA
CACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTTCGCTACAACCTTGGCGACAGAACTATC
ATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGAAGAGTTGGTGCAGAAGGCTACCTGGAT
CTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACAGACTTCTATATTGGAGGAGTATCTTCT
TTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGACAAGTTATCATAAATAATCAAGAATTA
CAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGTGGGTACAACACATGCAGAAATGGAGGT
GAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACATGTAACCAGTCTGTGTCCTGTTTGAAT
AATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGTACTTTGGGTTGGGTGGGAAGGTATTGT
GAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGATCCAAATTATAGAATGAGAAACCTCCAG
TTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGAATAGCTCAAAATGAAGAAAATGATTTT
CTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCTGTGCCTATGAGCTATAACAATGGCACA
TTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTACATAAATAACAGTCTAATTCTTTCCGAG
GATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGCTTTGAATATGGTAGAAAGGTAAATATC
GTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAGGAACCAAAAAACATTGAACTAATTAAA

>93557_93557_4_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000370616_length(amino acids)=1109AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS
SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQ
GCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSY
SCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLG
ERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDV

--------------------------------------------------------------
>93557_93557_5_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000370621_length(transcript)=4291nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCACTTATCCTCATTGTGATCTTGGAA
AAGCCAAAACCAGCAGAACGGAAAGTGAAGAAGGAGGCTTTATCCATAAGTGATCCATCTTTCAGAAGCAATGAGTTATCCTGGATGTCT
TTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCAGATGGTATCCTATTTTATGCTGCACAA
CACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTTCGCTACAACCTTGGCGACAGAACTATC
ATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGAAGAGTTGGTGCAGAAGGCTACCTGGAT
CTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACAGACTTCTATATTGGAGGAGTATCTTCT
TTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGACAAGTTATCATAAATAATCAAGAATTA
CAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGTGGGTACAACACATGCAGAAATGGAGGT
GAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACATGTAACCAGTCTGTGTCCTGTTTGAAT
AATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGTACTTTGGGTTGGGTGGGAAGGTATTGT
GAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGATCCAAATTATAGAATGAGAAACCTCCAG
TTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGAATAGCTCAAAATGAAGAAAATGATTTT
CTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCTGTGCCTATGAGCTATAACAATGGCACA
TTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTACATAAATAACAGTCTAATTCTTTCCGAG
GATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGCTTTGAATATGGTAGAAAGGTAAATATC
GTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAGGAACCAAAAAACATTGAACTAATTAAA
TTAGAAGGATACAATGTTTATGATGGAGATGAACAAAATGAGGTTACATAAGTTAACACTAGAGATTTTAGTACACACTATACATAAATG
CAGTTATTTTGATAGTTATTTCTTTGATACATTGCTTACGGGGAATCAACTGTTTACTATATTACCTGAAATAGTCTAAATGCTAACATA
TCTTTTTGATAAGATTGTAAAATGTCACTGAAGGTTCTGATTGTTTTTCCTACATCTAATTTATCTGTATATATTTTGATTCATGTTTTA
ACTCCATTAGTTCAGTGCTTATTCACAGAATGTGCTTATTCACTTTGCTTATTCACTTTTTACCTATCCCTAATGCTTACATTTTAAAAT
CAACGTGTAAACACAATTTTAAAAATCAATGTGTAAGCTGAACTTTAAAATGTTTAAAATTCAGTTGGGAATGAATTAGGGATAGGTACA

>93557_93557_5_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000370621_length(amino acids)=1109AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALILIVILEKPKPAERKVKKEALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNS
SVQLRYNLGDRTIILETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQ
GCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSY
SCLCTLGWVGRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLG
ERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDV

--------------------------------------------------------------
>93557_93557_6_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000503581_length(transcript)=4384nt_BP=757nt
TCAAAATTTCAACGATACTGAATGAGTCCCGCGGCGGGTTGGCTCGCGCTTCGTTGTCAGATCTGAGGCGAGGCTAGGTGAGCCGTGGGA
AGAAAAGAGGGAGCAGCTAGGGCGCGGGTCTCCCTCCTCCCGGAGTTTGGAACGGCTGAAGTTCACCTTCCAGCCCCTAGCGCCGTTCGC
GCCGCTAGGCCTGGCTTCTGAGGCGGTTGCGGTGCTCGGTCGCCGCCTAGGCGGGGCAGGGTGCGAGCAGGGGCTTCGGGCCACGCTTCT
CTTGGCGACAGGATTTTGCTGTGAAGTCCGTCCGGGAAACGGAGGAAAAAAAGAGTTGCGGGAGGCTGTCGGCTAATAACGGTTCTTGAT
ACATATTTGCCAGACTTCAAGATTTCAGAAAAGGGGTGAAAGAGAAGATTGCAACTTTGAGTCAGACCTGTAGGCCTGATAGACTGATTA
AACCACAGAAGGTGACCTGCTGAGAAAAGTGGTACAAATACTGGGAAAAACCTGCTCTTCTGCGTTAAGTGGGAGACAATGTCACAAGTT
AAAAGCTCTTATTCCTATGATGCCCCCTCGGATTTCATCAATTTTTCATCCTTGGATGATGAAGGAGATACTCAAAACATAGATTCATGG
TTTGAGGAGAAGGCCAATTTGGAGAATAAGTTACTGGGGAAGAATGGAACTGGAGGGCTTTTTCAGGGCAAAACTCCTTTGAGAAAGGCT
AATCTTCAGCAAGCTATTGTCACACCTTTGAAACCAGATGCAGGTTTATTCTTTCCATCTTTCAATGGGAATTCCTATTTAGAACTGCCC
TTTTTGAAGTTTGTCCTGGAGAAGGAACATAACAGAACTGTTACCATCTACTTGACTATAAAAACAAACAGTTTAAATGGAACTATTCTT
TACAGTAATGGGAATAATTGTGGAAAGCAGTTTCTTCATTTATTTCTTGTGGAAGGAAGGCCATCAGTTAAATATGGGTGTGGAAATTCT
CAAAATATTTTGACTGTTTCTGCTAATTACAGCATTAACACAAATGCATTCACCCCTATCACAATACGCTACACAACGCCTGTTGGCAGC
CCTGGAGTTGTTTGTATGATTGAAATGACTGCAGATGGAAAACCTCCAGTACAGAAGAAAGACACAGAGATTTCCCATGCCTCTCAGGCA
TATTTTGAATCAATGTTCCTTGGCCATATTCCTGCAAATGTTCAAATTCATAAGAAAGCAGGTCCTGTTTATGGGTTCAGGGGCTGCATT
CTAGACCTTCAAGTAAACAACAAAGAATTCTTCATCATCGATGAAGCACGACATGGAAAGAATATTGAGAACTGCCACGTCCCTTGGTGT
GCTCATCATCTGTGCCGCAACAATGGCACCTGCATCAGTGATAATGAAAATCTGTTTTGTGAGTGTCCAAGGCTGTATTCAGGCAAGCTG
TGCCAGTTTGCAAGTTGTGAAAACAACCCATGTGGAAATGGTGCCACCTGTGTTCCAAAATCCGGAACAGATATTGTCTGCCTCTGCCCA
TATGGGAGGTCTGGACCCCTCTGCACTGATGCTATTAATATTACTCAGCCAAGGTTCAGTGGCACAGATGCCTTTGGATACACCTCATTC
CTGGCTTATTCACGGATCTCAGACATCAGCTTCCATTATGAATTCCACCTGAAGTTTCAGCTGGCAAACAACCACTCAGCACTGCAAAAT
AACTTGATATTTTTTACTGGACAGAAAGGCCATGGGTTGAATGGCGATGACTTCCTGGCTGTGGGCCTGCTCAATGGCAGTGTGGTTTAT
AGTTATAACCTGGGGTCTGGCATAGCAAGCATCAGGAGCGAGCCCCTCAATCTGAGCCTTGGAGTCCACACTGTTCATCTGGGCAAGTTC
TTCCAAGAGGGCTGGCTGAAGGTAGATGATCATAAAAATAAATCCATTATCGCCCCAGGAAGACTGGTTGGTCTCAATGTCTTCAGTCAG
TTTTATGTAGGTGGCTACAGTGAATACACTCCAGATCTCTTACCAAATGGAGCAGATTTTAAAAATGGTTTTCAAGGCTGTATTTTCACT
CTTCAAGTTCGCACTGAGAAGGATGGCCATTTCAGAGGACTGGGAAATCCTGAGGGCCACCCAAATGCTGGACGCAGTGTTGGCCAGTGT
CATGCTTCTCCCTGCAGTTTAATGAAATGTGGCAATGGTGGGACATGCATAGAGAGTGGAACTAGTGTTTACTGCAATTGTACCACTGGG
TGGAAAGGATCATTCTGCACAGAGACAGTTTCTACCTGTGATCCTGAACATGACCCTCCACACCACTGTAGCAGAGGAGCAACCTGCATT
TCATTACCTCATGGATACACCTGTTTCTGTCCTCTAGGAACCACTGGAATCTACTGTGAACAAGCTTTATCCATAAGTGATCCATCTTTC
AGAAGCAATGAGTTATCCTGGATGTCTTTTGCTTCCTTTCATGTTCGAAAAAAGACACATATTCAATTGCAGTTTCAGCCTCTCGCTGCA
GATGGTATCCTATTTTATGCTGCACAACACTTAAAAGCCCAATCAGGTGATTTTTTATGCATCTCTTTAGTAAATAGTTCCGTTCAACTT
CGCTACAACCTTGGCGACAGAACTATCATTCTAGAAACTCTCCAAAAAGTAACTATAAACGGAAGTACTTGGCATATAATAAAAGCAGGA
AGAGTTGGTGCAGAAGGCTACCTGGATCTAGATGGGATAAATGTAACAGAAAAGGCCTCCACTAAAATGAGTTCTCTGGACACAAATACA
GACTTCTATATTGGAGGAGTATCTTCTTTAAATCTTGTAAATCCCATGGCAATAGAAAATGAACCTGTAGGTTTTCAAGGCTGTATCCGA
CAAGTTATCATAAATAATCAAGAATTACAATTAACTGAATTTGGAGCAAAAGGTGGCTCAAATGTAGGTGACTGTGATGGGACAGCCTGT
GGGTACAACACATGCAGAAATGGAGGTGAATGTACAGTAAATGGCACAACTTTTTCTTGCAGATGTTTGCCAGATTGGGCTGGAAATACA
TGTAACCAGTCTGTGTCCTGTTTGAATAATCTTTGCCTCCACCAATCTTTATGTATACCTGACCAATCATTTTCTTACAGTTGCCTGTGT
ACTTTGGGTTGGGTGGGAAGGTATTGTGAAAACAAAACTTCATTTTCAACTGCAAAATTTATGGGTAATTCTTACATTAAATACATTGAT
CCAAATTATAGAATGAGAAACCTCCAGTTCACTACTATATCCTTAAATTTCAGTACCACTAAAACAGAAGGTCTAATTGTATGGATGGGA
ATAGCTCAAAATGAAGAAAATGATTTTCTGGCAATTGGTCTCCATAATCAGACCTTGAAAATAGCAGTTAACTTGGGAGAAAGAATCTCT
GTGCCTATGAGCTATAACAATGGCACATTCTGTTGTAATAAATGGCACCATGTAGTTGTAATTCAAAATCAGACTCTTATCAAGGCCTAC
ATAAATAACAGTCTAATTCTTTCCGAGGATATTGATCCACATAAAAACTTTGTGGCTCTAAACTATGATGGCATTTGTTATCTAGGGGGC
TTTGAATATGGTAGAAAGGTAAATATCGTTACTCAAGAGATTTTTAAAACCAATTTTGTTGGCAAAATTAAAGATGTTGTATTTTTTCAG
GAACCAAAAAACATTGAACTAATTAAATTAGAAGGATACAATGTTTATGATGGAGATGAACAAAATGAGGTTACATAAGTTAACACTAGA
GATTTTAGTACACACTATACATAAATGCAGTTATTTTGATAGTTATTTCTTTGATACATTGCTTACGGGGAATCAACTGTTTACTATATT
ACCTGAAATAGTCTAAATGCTAACATATCTTTTTGATAAGATTGTAAAATGTCACTGAAGGTTCTGATTGTTTTTCCTACATCTAATTTA
TCTGTATATATTTTGATTCATGTTTTAACTCCATTAGTTCAGTGCTTATTCACAGAATGTGCTTATTCACTTTGCTTATTCACTTTTTAC
CTATCCCTAATGCTTACATTTTAAAATCAACGTGTAAACACAATTTTAAAAATCAATGTGTAAGCTGAACTTTAAAATGTTTAAAATTCA
GTTGGGAATGAATTAGGGATAGGTACAAATAAGAAAAAAATCAAGTTATTAATCAAAGGAAAAATAAAAATTATACAAAGCAATGTAACC
ATATTGTATTACATGGCTTAGCTACAACTTATTTATATGATTCAACAATGTAAAACTTGAACATAGATTTAAACCAAAAATTATTGCATG

>93557_93557_6_TPX2-EYS_TPX2_chr20_30347982_ENST00000340513_EYS_chr6_64791895_ENST00000503581_length(amino acids)=1088AA_BP=80
MLFCVKWETMSQVKSSYSYDAPSDFINFSSLDDEGDTQNIDSWFEEKANLENKLLGKNGTGGLFQGKTPLRKANLQQAIVTPLKPDAGLF
FPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAF
TPITIRYTTPVGSPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFRGCILDLQVNNKEFFIIDEAR
HGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQP
RFSGTDAFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAVGLLNGSVVYSYNLGSGIASIRSEPLN
LSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAPGRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGI
YCEQALSISDPSFRSNELSWMSFASFHVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIILETLQKV
TINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSSLNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAK
GGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCENKTSFST
AKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQNEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHH
VVVIQNQTLIKAYINNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFFQEPKNIELIKLEGYNVYD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for TPX2-EYS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for TPX2-EYS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for TPX2-EYS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTPX2C2239176Liver carcinoma1CTD_human
TgeneC1864446Retinitis Pigmentosa 255CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC0035334Retinitis Pigmentosa1CTD_human;GENOMICS_ENGLAND