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Fusion gene:FUS_PTMA (FusionGDB2 ID:HG2521TG5757) |
Fusion Gene Summary for FUS_PTMA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FUS_PTMA | Fusion gene ID: hg2521tg5757 | Hgene | Tgene | Gene symbol | FUS | PTMA | Gene ID | 2521 | 5757 |
| Gene name | FUS RNA binding protein | prothymosin alpha | |
| Synonyms | ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS|altFUS | TMSA | |
| Cytomap | 16p11.2 | 2q37.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | RNA-binding protein FUS75 kDa DNA-pairing proteinfus-like proteinfused in sarcomafusion gene in myxoid liposarcomaheterogeneous nuclear ribonucleoprotein P2oncogene FUSoncogene TLStranslocated in liposarcoma protein | prothymosin alphagene sequence 28prothymosin alpha proteinprothymosin-I+/- | |
| Modification date | 20240416 | 20240407 | |
| UniProtAcc | P35637 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000254108, ENST00000380244, ENST00000568685, ENST00000474990, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 41 X 30 X 43=52890 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 29 X 63 X 48=87696 |
| # samples | 72 | 136 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(72/52890*10)=-6.19885425859903 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(136/87696*10)=-6.01083248321094 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FUS [Title/Abstract] AND PTMA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | FUS(31191548)-PTMA(232576057), # samples:1 | ||
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Fusion Gene Breakpoints for FUS_PTMA |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| FUS | chr16 | 31191548 | PTMA | chr2 | 232576058 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for FUS_PTMA |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| FUS-PTMA | Condensate-Driven Transcriptional Rewiring / LLP M5 | FUS prion-like domain fuses to prothymosin alpha, driving phase-separated coactivation of p300/CBP and accelerated cell cycle entry. | p300/CBP HAT inhibitors; BET bromodomain inhibitors | Solid tumors and sarcomas |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| FUS-PTMA | Condensate-Driven Transcriptional Rewiring / LLP | FUS prion-like domain fuses to prothymosin alpha, driving phase-separated coactivation of p300/CBP and accelerated cell cycle entry. | p300/CBP HAT inhibitors; BET bromodomain inhibitors | Solid tumors and sarcomas | Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 33872798; Title: Prothymosin α promotes colorectal carcinoma chemoresistance through inducing lipid droplet accumulation.; PMID: 35297481; Title: Overexpression of prothymosin-α in glioma is associated with tumor aggressiveness and poor prognosis. |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FUS | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | FUS | GO:0006355 | regulation of DNA-templated transcription | 26124092 |
| Hgene | FUS | GO:0006357 | regulation of transcription by RNA polymerase II | 25453086 |
| Hgene | FUS | GO:0008380 | RNA splicing | 26124092 |
| Hgene | FUS | GO:0043484 | regulation of RNA splicing | 25453086|27731383 |
| Hgene | FUS | GO:0048255 | mRNA stabilization | 27378374 |
| Hgene | FUS | GO:0051260 | protein homooligomerization | 25453086 |
| Hgene | FUS | GO:1905168 | positive regulation of double-strand break repair via homologous recombination | 10567410 |
| Hgene | FUS | GO:1990000 | amyloid fibril formation | 22579281 |
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Fusion Genomic Features for FUS_PTMA |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + | 7.86e-03 | 9.92e-01 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for FUS_PTMA |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000254108 | ENST00000341369 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000254108 | ENST00000409115 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000254108 | ENST00000409321 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000254108 | ENST00000409683 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000254108 | ENST00000410064 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000254108 | ENST00000466801 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000341369 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000409115 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000409321 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000409683 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000410064 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000380244 | ENST00000466801 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000341369 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000409115 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000409321 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000409683 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000410064 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| 5CDS-3UTR | ENST00000568685 | ENST00000466801 | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576057 | + |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000380244 | ENST00000409683 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 8.82e-02 |
| ENST00000568685 | ENST00000466801 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 9.10e-01 |
| ENST00000568685 | ENST00000410064 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 8.44e-02 |
| ENST00000568685 | ENST00000409683 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.03e-01 |
| ENST00000568685 | ENST00000409321 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 3.70e-02 |
| ENST00000568685 | ENST00000409115 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.50e-01 |
| ENST00000568685 | ENST00000341369 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.45e-01 |
| ENST00000380244 | ENST00000466801 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 9.01e-01 |
| ENST00000380244 | ENST00000410064 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 5.19e-02 |
| ENST00000254108 | ENST00000341369 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.52e-01 |
| ENST00000380244 | ENST00000409321 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 3.53e-02 |
| ENST00000380244 | ENST00000409115 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.42e-01 |
| ENST00000380244 | ENST00000341369 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.25e-01 |
| ENST00000254108 | ENST00000466801 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 8.49e-01 |
| ENST00000254108 | ENST00000410064 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 4.98e-02 |
| ENST00000254108 | ENST00000409683 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 9.26e-02 |
| ENST00000254108 | ENST00000409321 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 4.64e-02 |
| ENST00000254108 | ENST00000409115 | FUS | chr16 | 31191548 | PTMA | chr2 | 232576057 | 0.00e+00 | 1.73e-01 |
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Fusion Protein Retained/Non-Retained Functional Features for FUS_PTMA |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
| No matching images found for ${hg}_${tg}. |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for FUS_PTMA |
| In-frame Fusion Transcript Sequences. |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
>FUS_PTMA_ENST00000254108_ENST00000341369_31191548_232576057 length=1094nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGA GGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTGAGAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGA TGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCG CCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAG GGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAA CCAGCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACTTGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTT TTGTGTATGTACTTAGCTGTACTATAAGTAGTTGGTTTGTATGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATG TTGTCCAACAATAAACAGGAATTTTATTTTGCTGAGTTGTTCTA >FUS_PTMA_ENST00000254108_ENST00000409115_31191548_232576057 length=1096nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGA GGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGG AGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCG TGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGG AGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCA GCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACTTGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTG TGTATGTACTTAGCTGTACTATAAGTAGTTGGTTTGTATGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATGTTG TCCAACAATAAACAGGAATTTTATTTTGCTGAGTTGTTCTAACAAA >FUS_PTMA_ENST00000254108_ENST00000409321_31191548_232576057 length=663nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGA GGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGG AGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCG TGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGG AGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAA >FUS_PTMA_ENST00000254108_ENST00000409683_31191548_232576057 length=835nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGA GGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGAGGATGGAGATGAAGA TGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATT CACCCTCCACTTCCCGTCTCAGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAA GAACCAAAACTTCCAAGGCCCTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGA GCGTTCTCTGTCCTACTTCTGACTTTACTTGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAA >FUS_PTMA_ENST00000254108_ENST00000410064_31191548_232576057 length=411nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGA GGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGG AGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGC >FUS_PTMA_ENST00000254108_ENST00000466801_31191548_232576057 length=118nt Breakpoint=118nt ACTTAAGCTTCGACGCAGGAGGCGGGGCTGCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACG >FUS_PTMA_ENST00000380244_ENST00000341369_31191548_232576057 length=1065nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTA ACGGGAATGCTGAGAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAG CTACGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGT CTCAGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAG GCCCTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACT TCTGACTTTACTTGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTGTGTATGTACTTAGCTGTACTATAAGT AGTTGGTTTGTATGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATGTTGTCCAACAATAAACAGGAATTTTATTT TGCTGAGTTGTTCTA >FUS_PTMA_ENST00000380244_ENST00000409115_31191548_232576057 length=1067nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTA ACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTA CGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTC AGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCC CTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACTTCT GACTTTACTTGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTGTGTATGTACTTAGCTGTACTATAAGTAGT TGGTTTGTATGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATGTTGTCCAACAATAAACAGGAATTTTATTTTGC TGAGTTGTTCTAACAAA >FUS_PTMA_ENST00000380244_ENST00000409321_31191548_232576057 length=634nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTA ACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTA CGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTC AGAATCTAAACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCC CTGCTTTTTTTCTTAAAAGTACTTTAAAAAGGAA >FUS_PTMA_ENST00000380244_ENST00000409683_31191548_232576057 length=806nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTA ACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGC GGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAA ACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTT TTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACT TGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAA >FUS_PTMA_ENST00000380244_ENST00000410064_31191548_232576057 length=382nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTA ACGGGAATGCTAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTA CGGGCAAGCGGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGC >FUS_PTMA_ENST00000380244_ENST00000466801_31191548_232576057 length=89nt Breakpoint=89nt GCTCAGTCCTCCAGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACG >FUS_PTMA_ENST00000568685_ENST00000341369_31191548_232576057 length=1053nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTG AGAATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGC GGGCAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAA ACGTGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTT TTCTTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACT TGTGGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTGTGTATGTACTTAGCTGTACTATAAGTAGTTGGTTTGTA TGAGATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATGTTGTCCAACAATAAACAGGAATTTTATTTTGCTGAGTTGTT CTA >FUS_PTMA_ENST00000568685_ENST00000409115_31191548_232576057 length=1055nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTA ATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGG CAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACG TGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTC TTAAAAGTACTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACTTGT GGTGTGACCATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAAAGCAAAAATGACAACAGAAAAACAATCTTATTCCGAGCATTCCAGTAACTTTTTTGTGTATGTACTTAGCTGTACTATAAGTAGTTGGTTTGTATGA GATGGTTAAAAAGGCCAAAGATAAAAGGTTTCTTTTTTTTTCCTTTTTTGTCTATGAAGTTGCTGTTTATTTTTTTTGGCCTGTTTGATGTATGTGTGAAACAATGTTGTCCAACAATAAACAGGAATTTTATTTTGCTGAGTTGTTCTA ACAAA >FUS_PTMA_ENST00000568685_ENST00000409321_31191548_232576057 length=622nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTA ATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGG CAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACG TGGTCACCTTCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTC TTAAAAGTACTTTAAAAAGGAA >FUS_PTMA_ENST00000568685_ENST00000409683_31191548_232576057 length=794nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTA ATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGGCAGCTGAAG ATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGCAAAAAAGGAAAAGTTAAACTAAAAAAAAAAAGGCCGCCGTGACCTATTCACCCTCCACTTCCCGTCTCAGAATCTAAACGTGGTCACCT TCGAGTAGAGAGGCCCGCCCGCCCACCGTGGGCAGTGCCACCCGCAGATGACACGCGCTCTCCACCACCCAACCCAAACCATGAGAATTTGCAACAGGGGAGGAAAAAAGAACCAAAACTTCCAAGGCCCTGCTTTTTTTCTTAAAAGTA CTTTAAAAAGGAAATTTGTTTGTATTTTTTATTTACATTTTATATTTTTGTACATATTGTTAGGGTCAGCCATTTTTAATGATCTCGGATGACCAAACCAGCCTTCGGAGCGTTCTCTGTCCTACTTCTGACTTTACTTGTGGTGTGACC ATGTTCATTATAATCTCAAAGGAGAAAAAAAACCTTGTAAAAAA >FUS_PTMA_ENST00000568685_ENST00000410064_31191548_232576057 length=370nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACGGACTTAAAGGAGAAGAAGGAAGTTGTGGAAGAGGCAGAAAATGGAAGAGACGCCCCTGCTAACGGGAATGCTA ATGAGGAAAATGGGGAGCAGGAGGCTGACAATGAGGTAGACGAAGAAGAGGAAGAAGGTGGGGAGGAAGAGGAGGAGGAAGAAGAAGGTGATGGTGAGGAAGAGGATGGAGATGAAGATGAGGAAGCTGAGTCAGCTACGGGCAAGCGGG CAGCTGAAGATGATGAGGATGACGATGTCGATACCAAGAAGCAGAAGACCGACGAGGATGACTAGACAGC >FUS_PTMA_ENST00000568685_ENST00000466801_31191548_232576057 length=77nt Breakpoint=77nt AGGCGTCGGTACTCAGCGGTGTTGGAACTTCGTTGCTTGCTTGCCTGTGCGCGCGTGCGCGGACATGGCCTCAAACG |
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Fusion Protein Sequence for FUS_PTMA |
| In-frame Fusion Protein Sequences. |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for FUS_PTMA |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
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Fusion Gene Exprssed Samples for FUS_PTMA |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STARFusion | 1000Genome | FUS | chr16 | 31191548 | + | PTMA | chr2 | 232576058 | + |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
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Related Drugs for FUS_PTMA |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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