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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:ABTB2_APIP (FusionGDB2 ID:HG25841TG51074)

Fusion Gene Summary for ABTB2_APIP

Fusion gene summary

Fusion gene information	Fusion gene name: ABTB2_APIP
	Fusion gene ID: hg25841tg51074
		Hgene	Tgene
	Gene symbol	ABTB2	APIP
	Gene ID	25841	51074
	Gene name	ankyrin repeat and BTB domain containing 2	APAF1 interacting protein
	Synonyms	ABTB2A\|BTBD22	APIP2\|CGI-29\|CGI29\|MMRP19\|hAPIP
	Cytomap	11p13	11p13
	Type of gene	protein-coding	protein-coding
	Description	ankyrin repeat and BTB/POZ domain-containing protein 2ankyrin repeat and BTB (POZ) domain containing 2	methylthioribulose-1-phosphate dehydrataseMTRu-1-P dehydrataseprobable methylthioribulose-1-phosphate dehydratase
	Modification date	20240305	20240416
	UniProtAcc	Q8N961	.
	Ensembl transtripts involved in fusion gene	ENST00000298992, ENST00000435224, ENST00000530814,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 14 X 12 X 6=1008	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 2 X 3 X 4=24
	# samples	23	4
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(23/100810)=-2.13178987255554 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(4/2410)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ABTB2 [Title/Abstract] AND APIP [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ABTB2(34378247)-APIP(34916657), # samples:1

Fusion gene breakpoints across ABTB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across APIP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for ABTB2_APIP

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
ABTB2	chr11	34186232	APIP	chr11	34916657
ABTB2	chr11	34378247	APIP	chr11	34916657
ABTB2	chr11	34186233	APIP	chr11	34916657

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for ABTB2_APIP

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
ABTB2-APIP	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation		ABTB2 promoter drives expression of APIP, suppressing Apaf-1-dependent apoptosome assembly and caspase-9 activation.		Apaf-1 activators; Smac mimetics; BH3 mimetics		Apoptosis-resistant epithelial carcinomas

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
ABTB2-APIP	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 32488114; Title: Genomic analyses of early responses to radiation inglioblastoma reveal new alterations at transcription,splicing, and translation levels.	ABTB2 promoter drives expression of APIP, suppressing Apaf-1-dependent apoptosome assembly and caspase-9 activation.		Apaf-1 activators; Smac mimetics; BH3 mimetics		Apoptosis-resistant epithelial carcinomas

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ABTB2 Q8N961	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	APIP	GO:0051289	protein homotetramerization	24367089

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Fusion Genomic Features for ABTB2_APIP

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ABTB2	chr11	34186232	-	APIP	chr11	34916657	-	3.84e-04	1.00e+00
ABTB2	chr11	34378247	-	APIP	chr11	34916657	-	1.00e-05	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for ABTB2_APIP

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000298992	ENST00000278359	ABTB2	chr11	34186232	-	APIP	chr11	34916657	-
Frame-shift	ENST00000298992	ENST00000395787	ABTB2	chr11	34186232	-	APIP	chr11	34916657	-
Frame-shift	ENST00000435224	ENST00000278359	ABTB2	chr11	34186232	-	APIP	chr11	34916657	-
Frame-shift	ENST00000435224	ENST00000395787	ABTB2	chr11	34186232	-	APIP	chr11	34916657	-
In-frame	ENST00000298992	ENST00000278359	ABTB2	chr11	34378247	-	APIP	chr11	34916657	-
In-frame	ENST00000298992	ENST00000395787	ABTB2	chr11	34378247	-	APIP	chr11	34916657	-
In-frame	ENST00000435224	ENST00000278359	ABTB2	chr11	34378247	-	APIP	chr11	34916657	-
In-frame	ENST00000435224	ENST00000395787	ABTB2	chr11	34378247	-	APIP	chr11	34916657	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000298992	ENST00000278359	ABTB2	chr11	34378247	APIP	chr11	34916657	555	202
ENST00000298992	ENST00000395787	ABTB2	chr11	34378247	APIP	chr11	34916657	555	266
ENST00000435224	ENST00000278359	ABTB2	chr11	34378247	APIP	chr11	34916657	1308	266
ENST00000435224	ENST00000395787	ABTB2	chr11	34378247	APIP	chr11	34916657	1308	445

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000298992	ENST00000278359	ABTB2	chr11	34378247	APIP	chr11	34916657	4.72e-04	1.00e+00
ENST00000298992	ENST00000395787	ABTB2	chr11	34378247	APIP	chr11	34916657	1.66e-03	9.98e-01
ENST00000435224	ENST00000278359	ABTB2	chr11	34378247	APIP	chr11	34916657	2.34e-03	9.98e-01
ENST00000435224	ENST00000395787	ABTB2	chr11	34378247	APIP	chr11	34916657	1.02e-02	9.90e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for ABTB2_APIP

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ABTB2

chr11:34378247

chr11:34916657

ENST00000298992

Q8N961

845_914

108.33333333333333

840.0

Domain

BTB

Hgene

ABTB2

chr11:34378247

chr11:34916657

ENST00000298992

Q8N961

521_550

108.33333333333333

840.0

Repeat

Note=ANK 1

Hgene

ABTB2

chr11:34378247

chr11:34916657

ENST00000298992

Q8N961

567_596

108.33333333333333

840.0

Repeat

Note=ANK 2

Hgene

ABTB2

chr11:34378247

chr11:34916657

ENST00000298992

Q8N961

606_635

108.33333333333333

840.0

Repeat

Note=ANK 3

Hgene

ABTB2

chr11:34378247

chr11:34916657

ENST00000298992

Q8N961

649_678

108.33333333333333

840.0

Repeat

Note=ANK 4

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for ABTB2_APIP

In-frame Fusion Transcript Sequences.

>ABTB2_APIP_ENST00000298992_ENST00000278359_34378247_34916657 length=1363nt 
 Breakpoint=555nt
AAGGCGCTGGCGGCCGGCGGCTGCCCCAGTTCTCCGCCGAGGCGGTGAGGCGCCTGGCCGGGCTGCTCCGCAGGGCACTGATCCGCGTGGCCCGCGAGGCGCAGCGCCTGAGCGTGCTGCACGCCAAGTGCACCCGCTTTGAGGTGCAGA
GCGCCGTGCGCCTGGTGCACAGCTGGGCGCTGGCCGAGAGCTGCGCGCTGGCAGCCGTCAAGGCGCTGTCCCTGTACAGCATGAGCGCCGGCGACGGGCTGCGCCGGGGCAAGTCCGCGCGCTGCGGCCTCACCTTCTCAGTGGGTCGCT
TTTTCCGCTGGATGGTGGACACCCGAATCTCCGTGCGCATCCACGAGTACGCAGCCATCTCCCTCACCGCCTGCATGGAGAACCTGGTGGAGGAGATCCGGGCCAGGGTGATGGCCAGCCACAGCCCTGATGGCGGAGGGGCCGGAGGCG
GGGAGGTGTCTGCTGAGGCCCTGGAGATGGTCATCAACAACGACGCCGAGCTCTGGGGCGTCTTGCAGCCCTATGAGCATCTCATCTGCGGCAAGAACGCCAATGGACAAGGAGCATCCAAGATACCTGATCCCAGAACTTTGCAAACAG
TTTTACCATTTAGGCTGGGTCACTGGGACTGGAGGAGGAATTAGCTTGAAGCATGGCGATGAAATCTACATTGCTCCTTCAGGAGTGCAAAAGGAACGAATTCAGCCTGAAGACATGTTTGTTTGTGATATAAATGAAAAGGACATAAGT
GGACCTTCGCCATCGAAGAAGCTAAAAAAAAGCCAGTGTACTCCTCTTTTCATGAATGCTTACACAATGAGAGGAGCAGGTGCAGTGATTCATACCCACTCTAAAGCTGCTGTGATGGCCACACTTCTCTTTCCAGGACGGGAGTTTAAA
ATTACACATCAAGAGATGATAAAAGGAATAAAGAAATGTACTTCCGGAGGGTATTATAGATATGATGATATGTTAGTGGTACCCATTATTGAGAATACACCTGAGGAGAAAGACCTCAAAGATAGAATGGCTCATGCAATGAATGAATAC
CCAGACTCCTGTGCAGTACTGGTCAGACGTCATGGAGTATATGTGTGGGGGGAAACATGGGAGAAGGCCAAAACCATGTGTGAGTGTTATGACTATTTATTTGATATTGCCGTATCAATGAAGAAAGTAGGACTTGATCCTTCACAGCTC
CCAGTTGGAGAAAATGGAATTGTCTAAGCCAAAAGAAAGTCTAATTATATACAGAGATAAAGCTAAACGTCCCTCCCACAACACGGAATTATGGGAGCTACAAGATGAGATTTGAGTGGGGACACAGAGCCAAACCATATCATCCAGCGT
CCAGGAAGATTCA

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657 length=1649nt 
 Breakpoint=555nt
AAGGCGCTGGCGGCCGGCGGCTGCCCCAGTTCTCCGCCGAGGCGGTGAGGCGCCTGGCCGGGCTGCTCCGCAGGGCACTGATCCGCGTGGCCCGCGAGGCGCAGCGCCTGAGCGTGCTGCACGCCAAGTGCACCCGCTTTGAGGTGCAGA
GCGCCGTGCGCCTGGTGCACAGCTGGGCGCTGGCCGAGAGCTGCGCGCTGGCAGCCGTCAAGGCGCTGTCCCTGTACAGCATGAGCGCCGGCGACGGGCTGCGCCGGGGCAAGTCCGCGCGCTGCGGCCTCACCTTCTCAGTGGGTCGCT
TTTTCCGCTGGATGGTGGACACCCGAATCTCCGTGCGCATCCACGAGTACGCAGCCATCTCCCTCACCGCCTGCATGGAGAACCTGGTGGAGGAGATCCGGGCCAGGGTGATGGCCAGCCACAGCCCTGATGGCGGAGGGGCCGGAGGCG
GGGAGGTGTCTGCTGAGGCCCTGGAGATGGTCATCAACAACGACGCCGAGCTCTGGGGCGTCTTGCAGCCCTATGAGCATCTCATCTGCGGCAAGAACGCCAATGGACAAGGAGCATCCAAGATACCTGATCCCAGAACTTTGCAAACAG
TTTTACCATTTAGGCTGGGTCACTGGGACTGGAGGAGGAATTAGCTTGAAGCATGGCGATGAAATCTACATTGCTCCTTCAGGAGTGCAAAAGGAACGAATTCAGCCTGAAGACATGTTTGTTTGTGATATAAATGAAAAGGACATAAGT
GGACCTTCGCCATCGAAGAAGCTAAAAAAAAGCCAGTGTACTCCTCTTTTCATGAATGCTTACACAATGAGAGGAGCAGGTGCAGTGATTCATACCCACTCTAAAGCTGCTGTGATGGCCACACTTCTCTTTCCAGGACGGGAGTTTAAA
ATTACACATCAAGAGATGATAAAAGGAATAAAGAAATGTACTTCCGGAGGGTATTATAGATATGATGATATGTTAGTGGTACCCATTATTGAGAATACACCTGAGGAGAAAGACCTCAAAGATAGAATGGCTCATGCAATGAATGAATAC
CCAGACTCCTGTGCAGTACTGGTCAGACGTCATGGAGTATATGTGTGGGGGGAAACATGGGAGAAGGCCAAAACCATGTGTGAGTGTTATGACTATTTATTTGATATTGCCGTATCAATGAAGAAAGTAGGACTTGATCCTTCACAGCTC
CCAGTTGGAGAAAATGGAATTGTCTAAGCCAAAAGAAAGTCTAATTATATACAGAGATAAAGCTAAACGTAATTATTATTTAAATGAAAGCTATTTTTTTAAATGAATTGAAATTTTTCATGATGCTACTAATTTGCCACTAAATACTGC
AAATGGTCACCCTGAATCTCTTCTGACATTGGATGTTATTTGCTTATATTCTTATAATTTTAAATGAGGGCACAGTGAAATGAAAATTTTATACTCTATGTTTCTGTTTATTTTTAAATCCTTAACAGCAAAATATTTGCCTTTAATTTC
TTTTTTATATATACTCTCAGAGAATTCCTCTTAATTTTTAAAGATGCTGGTGATAATAAAATTCATTAGAAAATTTCCTCATTGTGGAATGAGCATTCTCTTGTTTTAATGTTGGTGTCAGAAAATAAATATGAAACATTAAGTCCAAA

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657 length=2116nt 
 Breakpoint=1308nt
AGAAGTTTGCAGAGCGCTTTCTCGCCGGCTGGTCCCGGACTCGCGCTGCGCCCTGCGCCCTGCGCCGCCGCCTCCTCCTTCTGCCGCCGCCGCCCTGTTCTCCCGGGATTCCTTCTCTGTGGAGGACTGACTCTCTGCTTGTGGGAATTA
GAGGTGGACAAGGGGGAGTGCCGGGGGGTAGCGACGGGGTTCTTTCCAGTGGCAGCTGCGAGTCGGGACGCCGGGAGCGTGGGGCTCCTGCTGGCCACGGATCTCGGCCACCTTCCCGCGGCCTCCGGGCAGGCAATGCGGCCGCCGAGC
CCCGCGACGCAGAGAGGAAGGAGGGTGGCCCGGAGGGCCTAGAGCTTGTTTCTGCCCACTTGGGAAAGAGGGCATGGAGTTGTGAGTGCCCCTCGCTCGGCGACGCCGCCCTCGGCAGGCTCCCCATGGCCGGGACGTACAGCTCGACTC
TGAAGACGCTGGAGGACTTGACCTTGGACTCCGGGTATGGGGCCGGGGACTCGTGCCGCTCGCTCAGCCTCTCGTCCTCCAAGTCCAACTCGCAGGCGCTCAACTCTTCGGCGCAGCAGCACCGCGGGGCGGCCTGGTGGTGCTACTCCG
GCTCCATGAACAGCCGCCACAACAGCTGGGACACGGTGAACACGGTGCTGCCCGAGGACCCCGAAGTGGCCGACCTCTTCTCGCGCTGTCCGCGGCTCCCCGAGCTGGAGGAGTTCCCCTGGACCGAAGGAGACGTGGCCCGGGTGCTCC
GCAAAGGCGCTGGCGGCCGGCGGCTGCCCCAGTTCTCCGCCGAGGCGGTGAGGCGCCTGGCCGGGCTGCTCCGCAGGGCACTGATCCGCGTGGCCCGCGAGGCGCAGCGCCTGAGCGTGCTGCACGCCAAGTGCACCCGCTTTGAGGTGC
AGAGCGCCGTGCGCCTGGTGCACAGCTGGGCGCTGGCCGAGAGCTGCGCGCTGGCAGCCGTCAAGGCGCTGTCCCTGTACAGCATGAGCGCCGGCGACGGGCTGCGCCGGGGCAAGTCCGCGCGCTGCGGCCTCACCTTCTCAGTGGGTC
GCTTTTTCCGCTGGATGGTGGACACCCGAATCTCCGTGCGCATCCACGAGTACGCAGCCATCTCCCTCACCGCCTGCATGGAGAACCTGGTGGAGGAGATCCGGGCCAGGGTGATGGCCAGCCACAGCCCTGATGGCGGAGGGGCCGGAG
GCGGGGAGGTGTCTGCTGAGGCCCTGGAGATGGTCATCAACAACGACGCCGAGCTCTGGGGCGTCTTGCAGCCCTATGAGCATCTCATCTGCGGCAAGAACGCCAATGGACAAGGAGCATCCAAGATACCTGATCCCAGAACTTTGCAAA
CAGTTTTACCATTTAGGCTGGGTCACTGGGACTGGAGGAGGAATTAGCTTGAAGCATGGCGATGAAATCTACATTGCTCCTTCAGGAGTGCAAAAGGAACGAATTCAGCCTGAAGACATGTTTGTTTGTGATATAAATGAAAAGGACATA
AGTGGACCTTCGCCATCGAAGAAGCTAAAAAAAAGCCAGTGTACTCCTCTTTTCATGAATGCTTACACAATGAGAGGAGCAGGTGCAGTGATTCATACCCACTCTAAAGCTGCTGTGATGGCCACACTTCTCTTTCCAGGACGGGAGTTT
AAAATTACACATCAAGAGATGATAAAAGGAATAAAGAAATGTACTTCCGGAGGGTATTATAGATATGATGATATGTTAGTGGTACCCATTATTGAGAATACACCTGAGGAGAAAGACCTCAAAGATAGAATGGCTCATGCAATGAATGAA
TACCCAGACTCCTGTGCAGTACTGGTCAGACGTCATGGAGTATATGTGTGGGGGGAAACATGGGAGAAGGCCAAAACCATGTGTGAGTGTTATGACTATTTATTTGATATTGCCGTATCAATGAAGAAAGTAGGACTTGATCCTTCACAG
CTCCCAGTTGGAGAAAATGGAATTGTCTAAGCCAAAAGAAAGTCTAATTATATACAGAGATAAAGCTAAACGTCCCTCCCACAACACGGAATTATGGGAGCTACAAGATGAGATTTGAGTGGGGACACAGAGCCAAACCATATCATCCAG
CGTCCAGGAAGATTCA

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657 length=2402nt 
 Breakpoint=1308nt
AGAAGTTTGCAGAGCGCTTTCTCGCCGGCTGGTCCCGGACTCGCGCTGCGCCCTGCGCCCTGCGCCGCCGCCTCCTCCTTCTGCCGCCGCCGCCCTGTTCTCCCGGGATTCCTTCTCTGTGGAGGACTGACTCTCTGCTTGTGGGAATTA
GAGGTGGACAAGGGGGAGTGCCGGGGGGTAGCGACGGGGTTCTTTCCAGTGGCAGCTGCGAGTCGGGACGCCGGGAGCGTGGGGCTCCTGCTGGCCACGGATCTCGGCCACCTTCCCGCGGCCTCCGGGCAGGCAATGCGGCCGCCGAGC
CCCGCGACGCAGAGAGGAAGGAGGGTGGCCCGGAGGGCCTAGAGCTTGTTTCTGCCCACTTGGGAAAGAGGGCATGGAGTTGTGAGTGCCCCTCGCTCGGCGACGCCGCCCTCGGCAGGCTCCCCATGGCCGGGACGTACAGCTCGACTC
TGAAGACGCTGGAGGACTTGACCTTGGACTCCGGGTATGGGGCCGGGGACTCGTGCCGCTCGCTCAGCCTCTCGTCCTCCAAGTCCAACTCGCAGGCGCTCAACTCTTCGGCGCAGCAGCACCGCGGGGCGGCCTGGTGGTGCTACTCCG
GCTCCATGAACAGCCGCCACAACAGCTGGGACACGGTGAACACGGTGCTGCCCGAGGACCCCGAAGTGGCCGACCTCTTCTCGCGCTGTCCGCGGCTCCCCGAGCTGGAGGAGTTCCCCTGGACCGAAGGAGACGTGGCCCGGGTGCTCC
GCAAAGGCGCTGGCGGCCGGCGGCTGCCCCAGTTCTCCGCCGAGGCGGTGAGGCGCCTGGCCGGGCTGCTCCGCAGGGCACTGATCCGCGTGGCCCGCGAGGCGCAGCGCCTGAGCGTGCTGCACGCCAAGTGCACCCGCTTTGAGGTGC
AGAGCGCCGTGCGCCTGGTGCACAGCTGGGCGCTGGCCGAGAGCTGCGCGCTGGCAGCCGTCAAGGCGCTGTCCCTGTACAGCATGAGCGCCGGCGACGGGCTGCGCCGGGGCAAGTCCGCGCGCTGCGGCCTCACCTTCTCAGTGGGTC
GCTTTTTCCGCTGGATGGTGGACACCCGAATCTCCGTGCGCATCCACGAGTACGCAGCCATCTCCCTCACCGCCTGCATGGAGAACCTGGTGGAGGAGATCCGGGCCAGGGTGATGGCCAGCCACAGCCCTGATGGCGGAGGGGCCGGAG
GCGGGGAGGTGTCTGCTGAGGCCCTGGAGATGGTCATCAACAACGACGCCGAGCTCTGGGGCGTCTTGCAGCCCTATGAGCATCTCATCTGCGGCAAGAACGCCAATGGACAAGGAGCATCCAAGATACCTGATCCCAGAACTTTGCAAA
CAGTTTTACCATTTAGGCTGGGTCACTGGGACTGGAGGAGGAATTAGCTTGAAGCATGGCGATGAAATCTACATTGCTCCTTCAGGAGTGCAAAAGGAACGAATTCAGCCTGAAGACATGTTTGTTTGTGATATAAATGAAAAGGACATA
AGTGGACCTTCGCCATCGAAGAAGCTAAAAAAAAGCCAGTGTACTCCTCTTTTCATGAATGCTTACACAATGAGAGGAGCAGGTGCAGTGATTCATACCCACTCTAAAGCTGCTGTGATGGCCACACTTCTCTTTCCAGGACGGGAGTTT
AAAATTACACATCAAGAGATGATAAAAGGAATAAAGAAATGTACTTCCGGAGGGTATTATAGATATGATGATATGTTAGTGGTACCCATTATTGAGAATACACCTGAGGAGAAAGACCTCAAAGATAGAATGGCTCATGCAATGAATGAA
TACCCAGACTCCTGTGCAGTACTGGTCAGACGTCATGGAGTATATGTGTGGGGGGAAACATGGGAGAAGGCCAAAACCATGTGTGAGTGTTATGACTATTTATTTGATATTGCCGTATCAATGAAGAAAGTAGGACTTGATCCTTCACAG
CTCCCAGTTGGAGAAAATGGAATTGTCTAAGCCAAAAGAAAGTCTAATTATATACAGAGATAAAGCTAAACGTAATTATTATTTAAATGAAAGCTATTTTTTTAAATGAATTGAAATTTTTCATGATGCTACTAATTTGCCACTAAATAC
TGCAAATGGTCACCCTGAATCTCTTCTGACATTGGATGTTATTTGCTTATATTCTTATAATTTTAAATGAGGGCACAGTGAAATGAAAATTTTATACTCTATGTTTCTGTTTATTTTTAAATCCTTAACAGCAAAATATTTGCCTTTAAT
TTCTTTTTTATATATACTCTCAGAGAATTCCTCTTAATTTTTAAAGATGCTGGTGATAATAAAATTCATTAGAAAATTTCCTCATTGTGGAATGAGCATTCTCTTGTTTTAATGTTGGTGTCAGAAAATAAATATGAAACATTAAGTCCA
AA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

Top

Fusion Protein Sequence for ABTB2_APIP

In-frame Fusion Protein Sequences.

>ABTB2_APIP_ENST00000298992_ENST00000278359_34378247_34916657 length=202nt
MEAEESEKAATEQEPLEGTEQTLDAEEEQEESEEAACGSKKRVVPGIVYLGHIPPRFRPLHVRNLLSAYGEVGRVFFQAEELEPVQATQNKTGKYVPPSLRDGASRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRI
YLAKDKTTGQSKGFAFISFHRREDAARAIAGVSGFGYDHLILNVEWAKPSTN

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657 length=266nt
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657 length=266nt
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657 length=445nt
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

Top

Personalized Fusion Protein Sequence for ABTB2_APIP

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.Q69H_266_Q93H length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIHPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.C188S_266_C212S length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSSAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.V197I_266_V221I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGIYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.S95N_266_S119N length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKNQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.H52Y_266_H76Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKYGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.T203K_266_T227K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGEKWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.L100I_266_L124I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPIFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.T167A_266_T191A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENAPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.L50F_266_L74F length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISFKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.L173I_266_L197I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDIKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.I220T_266_I244T length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDTAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.H137R_266_H161R length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITRQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.R67Q_266_R91Q length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKEQIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.R131Q_266_R155Q length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGQEFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.V222A_266_V246A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAASMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.R131W_266_R155W length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGWEFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.W200L_266_W224L length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVLGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.A178D_266_A202D length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMDHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.L27M_266_L51M length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYMIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.G45E_266_G69E length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTEGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.D157Y_266_D181Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDYMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.E165K_266_E189K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIKNTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.E183K_266_E207K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNKYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.H23Y_266_H47Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEYPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.K51N_266_K75N length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLNHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.E183G_266_E207G length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNGYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000298992_ENST00000395787_34378247_34916657_3-gene_p.G240A_266_G264A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENAIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.Q69H_266_Q93H length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIHPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.C188S_266_C212S length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSSAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.V197I_266_V221I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGIYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.S95N_266_S119N length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKNQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.H52Y_266_H76Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKYGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.T203K_266_T227K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGEKWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.L100I_266_L124I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPIFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.T167A_266_T191A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENAPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.L50F_266_L74F length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISFKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.L173I_266_L197I length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDIKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.I220T_266_I244T length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDTAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.H137R_266_H161R length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITRQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.R67Q_266_R91Q length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKEQIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.R131Q_266_R155Q length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGQEFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.V222A_266_V246A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAASMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.R131W_266_R155W length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGWEFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.W200L_266_W224L length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVLGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.A178D_266_A202D length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMDHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.L27M_266_L51M length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYMIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.G45E_266_G69E length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTEGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.D157Y_266_D181Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDYMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.E165K_266_E189K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIKNTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.E183K_266_E207K length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNKYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.H23Y_266_H47Y length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEYPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.K51N_266_K75N length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLNHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.E183G_266_E207G length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNGYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENGIV

>ABTB2_APIP_ENST00000435224_ENST00000278359_34378247_34916657_3-gene_p.G240A_266_G264A length=266AA
MMAEGPEAGRCLLRPWRWSSTTTPSSGASCSPMSISSAARTPMDKEHPRYLIPELCKQFYHLGWVTGTGGGISLKHGDEIYIAPSGVQKERIQPEDMFVCDINEKDISGPSPSKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATL
LFPGREFKITHQEMIKGIKKCTSGGYYRYDDMLVVPIIENTPEEKDLKDRMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKVGLDPSQLPVGENAIV

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.M187K_445_M309K length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSKSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.I223T_445_I345T length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRTHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.G260W_445_G382W length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGWEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.M235T_445_M357T length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACTENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.T204A_445_T326A length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLAFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.D274N_445_D396N length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNNAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.V270I_445_V392I length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMIINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.D253Y_445_D375Y length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPYGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.A275T_445_A397T length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDTELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.E276D_445_E398D length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDADLWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.A257V_445_A379V length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGVGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.A264T_445_A386T length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSTEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.V221M_445_V343M length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISMRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.A257D_445_A379D length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGDGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.R245M_445_R367M length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRAMVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

>ABTB2_APIP_ENST00000435224_ENST00000395787_34378247_34916657_5-gene_p.I271M_445_I393M length=445AA
MRRRLLLLPPPPCSPGIPSLWRTDSLLVGIRGGQGGVPGGSDGVLSSGSCESGRRERGAPAGHGSRPPSRGLRAGNAAAEPRDAERKEGGPEGLELVSAHLGKRAWSCECPSLGDAALGRLPMAGTYSSTLKTLEDLTLDSGYGAGDSCR
SLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAA
VKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVMNNDAELWGVLQPYEHLICGKNANGQGASKIPDPRTLQTVLPFRLGHWDWRRN

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-37-4130-01A	3-gene	p.Q69H	266	Q93H
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-61-2109-01A	3-gene	p.C188S	266	C212S
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-A5-A0G2-01A	3-gene	p.V197I	266	V221I
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-A5-A1OF-01A	3-gene	p.S95N	266	S119N
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-AZ-4682-01B	3-gene	p.H52Y	266	H76Y
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-B5-A0K4-01A	3-gene	p.T203K	266	T227K
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-B5-A11E-01A	3-gene	p.L100I	266	L124I
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-BR-6452-01A	3-gene	p.T167A	266	T191A
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-C5-A2LX-01A	3-gene	p.L50F	266	L74F
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-D3-A2JD-06A	3-gene	p.L173I	266	L197I
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-DF-A2KU-01A	3-gene	p.I220T	266	I244T
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-DH-A66B-01A	3-gene	p.H137R	266	H161R
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-E7-A7XN-01A	3-gene	p.R67Q	266	R91Q
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-EE-A2GR-06A	3-gene	p.R131Q	266	R155Q
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-EO-A22U-01A	3-gene	p.V222A	266	V246A
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-EO-A3AY-01A	3-gene	p.R131W	266	R155W
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-EP-A2KB-01A	3-gene	p.W200L	266	W224L
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-FI-A2D5-01A	3-gene	p.A178D	266	A202D
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-GN-A26D-06A	3-gene	p.L27M	266	L51M
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-HF-7134-01A	3-gene	p.G45E	266	G69E
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-KQ-A41N-01A	3-gene	p.D157Y	266	D181Y
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-KQ-A41R-01A	3-gene	p.E165K	266	E189K
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-MF-A522-01A	3-gene	p.E183K	266	E207K
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-MX-A5UJ-01A	3-gene	p.H23Y	266	H47Y
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-SX-A71S-01A	3-gene	p.K51N	266	K75N
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-VQ-A8PP-01A	3-gene	p.E183G	266	E207G
ENST00000298992_ENST00000395787_34378247_34916657	TCGA-XF-A9ST-01A	3-gene	p.G240A	266	G264A
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-37-4130-01A	3-gene	p.Q69H	266	Q93H
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-61-2109-01A	3-gene	p.C188S	266	C212S
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-A5-A0G2-01A	3-gene	p.V197I	266	V221I
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-A5-A1OF-01A	3-gene	p.S95N	266	S119N
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-AZ-4682-01B	3-gene	p.H52Y	266	H76Y
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-B5-A0K4-01A	3-gene	p.T203K	266	T227K
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-B5-A11E-01A	3-gene	p.L100I	266	L124I
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-BR-6452-01A	3-gene	p.T167A	266	T191A
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-C5-A2LX-01A	3-gene	p.L50F	266	L74F
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-D3-A2JD-06A	3-gene	p.L173I	266	L197I
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-DF-A2KU-01A	3-gene	p.I220T	266	I244T
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-DH-A66B-01A	3-gene	p.H137R	266	H161R
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-E7-A7XN-01A	3-gene	p.R67Q	266	R91Q
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-EE-A2GR-06A	3-gene	p.R131Q	266	R155Q
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-EO-A22U-01A	3-gene	p.V222A	266	V246A
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-EO-A3AY-01A	3-gene	p.R131W	266	R155W
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-EP-A2KB-01A	3-gene	p.W200L	266	W224L
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-FI-A2D5-01A	3-gene	p.A178D	266	A202D
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-GN-A26D-06A	3-gene	p.L27M	266	L51M
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-HF-7134-01A	3-gene	p.G45E	266	G69E
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-KQ-A41N-01A	3-gene	p.D157Y	266	D181Y
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-KQ-A41R-01A	3-gene	p.E165K	266	E189K
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-MF-A522-01A	3-gene	p.E183K	266	E207K
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-MX-A5UJ-01A	3-gene	p.H23Y	266	H47Y
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-SX-A71S-01A	3-gene	p.K51N	266	K75N
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-VQ-A8PP-01A	3-gene	p.E183G	266	E207G
ENST00000435224_ENST00000278359_34378247_34916657	TCGA-XF-A9ST-01A	3-gene	p.G240A	266	G264A
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-34-5928-01A	5-gene	p.M187K	445	M309K
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-5K-AAAP-01A	5-gene	p.I223T	445	I345T
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-97-8177-01A	5-gene	p.G260W	445	G382W
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-AA-3984-01A	5-gene	p.M235T	445	M357T
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-AA-A010-01A	5-gene	p.T204A	445	T326A
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-AN-A046-01A	5-gene	p.D274N	445	D396N
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-AP-A1DK-01A	5-gene	p.V270I	445	V392I
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-B0-4827-01A	5-gene	p.D253Y	445	D375Y
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-B5-A0JY-01A	5-gene	p.A275T	445	A397T
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-B8-5550-01A	5-gene	p.E276D	445	E398D
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-CD-A4MG-01A	5-gene	p.A257V	445	A379V
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-CK-5916-01A	5-gene	p.A264T	445	A386T
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-DF-A2KN-01A	5-gene	p.V221M	445	V343M
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-EE-A2MG-06A	5-gene	p.A257D	445	A379D
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-EO-A22R-01A	5-gene	p.R245M	445	R367M
ENST00000435224_ENST00000395787_34378247_34916657	TCGA-Q1-A73O-01A	5-gene	p.I271M	445	I393M

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for ABTB2_APIP

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		BRCA	TCGA-AR-A256-01A	ABTB2	chr11	34186232	-	APIP	chr11	34916657	-
ChimerDB		STAD	TCGA-CG-4449-01A	ABTB2	chr11	34378247	-	APIP	chr11	34916657	-
TCGAfusionPortal		BRCA	TCGA-AR-A256-01A	ABTB2	chr11	34186233	-	APIP	chr11	34916657	-

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for ABTB2_APIP

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status