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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:C20orf194_TDRD10 (FusionGDB2 ID:HG25943TG126668)

Fusion Gene Summary for C20orf194_TDRD10

Fusion gene summary

Fusion gene information	Fusion gene name: C20orf194_TDRD10
	Fusion gene ID: hg25943tg126668
		Hgene	Tgene
	Gene symbol	C20orf194	TDRD10
	Gene ID	25943	126668
	Gene name	dynein axonemal assembly factor 9	tudor domain containing 10
	Synonyms	C20orf194	-
	Cytomap	20p13	1q21.3
	Type of gene	protein-coding	protein-coding
	Description	dynein axonemal assembly factor 9shulinuncharacterized protein C20orf194	tudor domain-containing protein 10
	Modification date	20240305	20240305
	UniProtAcc	Q5TEA3	.
	Ensembl transtripts involved in fusion gene	ENST00000252032, ENST00000453730, ENST00000498079,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 11 X 18 X 10=1980	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 9 X 7=252
	# samples	20	11
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(20/198010)=-3.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(11/25210)=-1.19592020997526 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: C20orf194 [Title/Abstract] AND TDRD10 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	C20orf194(3354694)-TDRD10(154514499), # samples:1

Fusion gene breakpoints across C20orf194 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TDRD10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for C20orf194_TDRD10

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
C20orf194	chr20	3354694	TDRD10	chr1	3354694
C20orf194	chr20	3354695	TDRD10	chr1	154514500
C20ORF194	chr20	3374048	TDRD10	chr1	154542024

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for C20orf194_TDRD10

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
C20orf194 Q5TEA3	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

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Fusion Genomic Features for C20orf194_TDRD10

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
C20orf194	chr20	3354694	-	TDRD10	chr1	154514499	+	1.22e-04	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for C20orf194_TDRD10

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000252032	ENST00000479937	C20orf194	chr20	3354694	-	TDRD10	chr1	154514499	+
In-frame	ENST00000252032	ENST00000368480	C20orf194	chr20	3354694	-	TDRD10	chr1	154514499	+
In-frame	ENST00000252032	ENST00000368482	C20orf194	chr20	3354694	-	TDRD10	chr1	154514499	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000252032	ENST00000368480	C20orf194	chr20	3354694	TDRD10	chr1	154514499	680	432
ENST00000252032	ENST00000368482	C20orf194	chr20	3354694	TDRD10	chr1	154514499	680	491

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000252032	ENST00000368480	C20orf194	chr20	3354694	TDRD10	chr1	154514499	1.64e-03	9.98e-01
ENST00000252032	ENST00000368482	C20orf194	chr20	3354694	TDRD10	chr1	154514499	1.57e-03	9.98e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000252032	ENST00000479937	C20orf194	chr20	3354694	TDRD10	chr1	154514499	0.00e+00	5.32e-03

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Fusion Protein Retained/Non-Retained Functional Features for C20orf194_TDRD10

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

C20orf194_TDRD10_chr20-3354694_chr1-154514499.png

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

C20orf194

chr20:3354694

chr1:154514499

ENST00000252032

Q5TEA3

11_27

204.0

1178.0

Compositional bias

Low complexity

Hgene

C20orf194

chr20:3354694

chr1:154514499

ENST00000252032

Q5TEA3

1_27

204.0

1178.0

Region

Disordered

Tgene

TDRD10

chr20:3354694

chr1:154514499

ENST00000368480

Q5VZ19

216_237

123.0

367.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TDRD10

chr20:3354694

chr1:154514499

ENST00000368480

Q5VZ19

210_317

123.0

367.0

Domain

Note=Tudor

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

TDRD10

chr20:3354694

chr1:154514499

ENST00000368480

Q5VZ19

34_107

123.0

367.0

Domain

RRM

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for C20orf194_TDRD10

In-frame Fusion Transcript Sequences.

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499 length=2002nt 
 Breakpoint=680nt
GCCGCCCTGCGGGCAACTGAGACCCTCGCAGCTGCACCGTCCTCCTCCGCCGCCAGTCGTCCGCCGCCATGGACGTGTACCCCCCGCGCCGGCAGGGGCTGCCCCGCGCTCGGTCCCCTGGCGGCTCCAGCCGCGGGTCACCCTCCGTCA
GCTGCAGTCGACTTCGGCAGGTTCAGAGCATCCTGACCCAGAGCAGCAAGTCTCGGCCGGATGGGATCCTCTGCATCCTAGGAATCGATAGCAGGTACAATGAAGGCTGCAGAGAGCTGGCAAATTATCTTCTATTTGGTTTGTACAATC
AGAATACCAGTGATTTTGAGAAAACGGGATTTTCTGAAGAAGTACTAGATGATGTAATTATATTGATTAAATCGGATAGCGTCCATCTGTACTGTAATCCTGTAAACTTTCGCTATCTCTTACCTTATGTGGCACATTGGAGAAATCTGC
ATTTCCACTGCATGACCGAAAATGAGTATGAAGATGAAGAAGCCGCAGAAGAATTTAAAATTACCAGCTTTGTGGACATGGTTCGAGACTGTAGTAGAATTGGCATTCCTTACAGCTCCCAAGGTCACTTGCAGATATTTGATATGTTTG
TGGTGGAGAAATGGCCAATTGTACAGGCCTTTGCACTTGAGGGCATTGGAGGGGATGGATTTTTTACCATGAAATATGAGGTGTTGGAGAAGGCTTCTGGTGAAGGATTTGGCAAAACCGCCGCTATTATACAGCTCGCTCCTAAAGCTC
CTGTTGACCTGTGTGAGACAGAGAAACTGAGGGCAGCCTTCTTTGCAGTCCCGTTGGAAATGAGAGGGTCCTTCCTGGTGCTGCTCCTGAGGGAATGCTTCCGAGACCTGAGCTGGCTGGCACTCATCCATAGCGTCCGTGGGGAGGCGG
GGCTGCTGGTGACGAGTATCGTCCCGAAGACCCCGTTTTTCTGGGCTATGCACGTCACTGAGGCTCTGCACCAGAACATGCAGGCTCTGTTTAGCACCCTGGCTCAGGCGGAGGAGCAGCAGCCCTACCTGGAGGGCTCCACCGTTATGC
GCGGGACTCGCTGTCTGGCAGAGTACCACCTGGGGGATTATGGACACGCCTGGAACAGGTGTTGGGTGCTGGACAGGGTGGACACCTGGGCTGTGGTCATGTTCATTGATTTTGGACAGTTGGCCACCATCCCTGTGCAGTCTCTGCGCA
GCCTAGACAGCGACGACTTCTGGACCATCCCACCCCTGACTCAGCCATTCATGCTGGAGAAAGACATTTTGAGTTCGTATGAGGTTGTCCATCGAATCCTCAAAGGGAAAATCACTGGTGCTTTGAACTCGGCGGTAACTGCTCCTGCAT
CTAACTTGGCTGTTGTCCCTCCACTCCTGCCCTTGGGGTGTCTGCAGCAGGCTGCTGCCTAGGCCTGGACACAGTATTTACCTGGCATTCTTTTAGATCAAACGAACTGGTTATCTGAGGGGTTGGGTGAACTGGCTCGGGTGGGCCTTC
CTTCCCACCAAGGCTTTGTCTTTCTCTTCCAGTTGCACATCCTAAAGTTTGAAGAGTCTAAATAACGGGGCTTCCCTCAGCATGTTCCCTCTCCTGTTTGCCACGGATCCAGAGGCCACCTGCCCTGTCTTCTCGTACCCCTTTCACTCT
TGAGGCCTGGGAGGTGAAAAAGGCCAGACTGTGCCCAGGATTGATTCAATTTTGCTTTTACTCCCAGCTTCCCTCTCAAAAGAGAGTGAAGTCTCATTTGTCATGTGTCTTCAGTTCCCCAACTTGGCATGAACATTTGAACCAAACATA
GGAAACTACCATTAGGTTGAAAGCCTGAGGCAGCTGGGATGGTCTTTCTTGTGTCTCTTCTTTGCACCCCAGAGCATGATATAAGTGGTCCTAACAGATTCTGGATAATGGAGAAGCCCTCTGCTGGTTTTCCTGGCATTCCATGTAGAA
TAGGTAGAGAATATTTAACCAATGAGCAAATAAATGTTGGCATGTTTCATGA

>C20orf194_TDRD10_ENST00000252032_ENST00000368482_3354694_154514499 length=1804nt 
 Breakpoint=680nt
GCCGCCCTGCGGGCAACTGAGACCCTCGCAGCTGCACCGTCCTCCTCCGCCGCCAGTCGTCCGCCGCCATGGACGTGTACCCCCCGCGCCGGCAGGGGCTGCCCCGCGCTCGGTCCCCTGGCGGCTCCAGCCGCGGGTCACCCTCCGTCA
GCTGCAGTCGACTTCGGCAGGTTCAGAGCATCCTGACCCAGAGCAGCAAGTCTCGGCCGGATGGGATCCTCTGCATCCTAGGAATCGATAGCAGGTACAATGAAGGCTGCAGAGAGCTGGCAAATTATCTTCTATTTGGTTTGTACAATC
AGAATACCAGTGATTTTGAGAAAACGGGATTTTCTGAAGAAGTACTAGATGATGTAATTATATTGATTAAATCGGATAGCGTCCATCTGTACTGTAATCCTGTAAACTTTCGCTATCTCTTACCTTATGTGGCACATTGGAGAAATCTGC
ATTTCCACTGCATGACCGAAAATGAGTATGAAGATGAAGAAGCCGCAGAAGAATTTAAAATTACCAGCTTTGTGGACATGGTTCGAGACTGTAGTAGAATTGGCATTCCTTACAGCTCCCAAGGTCACTTGCAGATATTTGATATGTTTG
TGGTGGAGAAATGGCCAATTGTACAGGCCTTTGCACTTGAGGGCATTGGAGGGGATGGATTTTTTACCATGAAATATGAGGTGTTGGAGAAGGCTTCTGGTGAAGGATTTGGCAAAACCGCCGCTATTATACAGCTCGCTCCTAAAGCTC
CTGTTGACCTGTGTGAGACAGAGAAACTGAGGGCAGCCTTCTTTGCAGTCCCGTTGGAAATGAGAGGGTCCTTCCTGGTGCTGCTCCTGAGGGAATGCTTCCGAGACCTGAGCTGGCTGGCACTCATCCATAGCGTCCGTGGGGAGGCGG
GGCTGCTGGTGACGAGTATCGTCCCGAAGACCCCGTTTTTCTGGGCTATGCACGTCACTGAGGCTCTGCACCAGAACATGCAGGCTCTGTTTAGCACCCTGGCTCAGGCGGAGGAGCAGCAGCCCTACCTGGAGGGCTCCACCGTTATGC
GCGGGACTCGCTGTCTGGCAGAGTACCACCTGGGGGATTATGGACACGCCTGGAACAGGTGTTGGGTGCTGGACAGGGTGGACACCTGGGCTGTGGTCATGTTCATTGATTTTGGACAGTTGGCCACCATCCCTGTGCAGTCTCTGCGCA
GCCTAGACAGCGACGACTTCTGGACCATCCCACCCCTGACTCAGCCATTCATGCTGGAGAAAGACATTTTGAGTTCGTATGAGGTTGTCCATCGAATCCTCAAAGGGAAAATCACTGGTGCTTTGAACTCGGCGTTGCACATCCTAAAGT
TTGAAGAGTCTAAATAACGGGGCTTCCCTCAGCATGTTCCCTCTCCTGTTTGCCACGGATCCAGAGGCCACCTGCCCTGTCTTCTCGTACCCCTTTCACTCTTGAGGCCTGGGAGGTGAAAAAGGCCAGACTGTGCCCAGGATTGATTCA
ATTTTGCTTTTACTCCCAGCTTCCCTCTCAAAAGAGAGTGAAGTCTCATTTGTCATGTGTCTTCAGTTCCCCAACTTGGCATGAACATTTGAACCAAACATAGGAAACTACCATTAGGTTGAAAGCCTGAGGCAGCTGGGATGGTCTTTC
TTGTGTCTCTTCTTTGCACCCCAGAGCATGATATAAGTGGTCCTAACAGATTCTGGATAATGGAGAAGCCCTCTGCTGGTTTTCCTGGCATTCCATGTAGAATAGGTAGAGAATATTTAACCAATGAGCAAATAAATGTTGGCATGTTTC
ATGA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

>C20orf194_TDRD10_ENST00000252032_ENST00000479937_3354694_154514499 length=680nt 
 Breakpoint=680nt
GCCGCCCTGCGGGCAACTGAGACCCTCGCAGCTGCACCGTCCTCCTCCGCCGCCAGTCGTCCGCCGCCATGGACGTGTACCCCCCGCGCCGGCAGGGGCTGCCCCGCGCTCGGTCCCCTGGCGGCTCCAGCCGCGGGTCACCCTCCGTCA
GCTGCAGTCGACTTCGGCAGGTTCAGAGCATCCTGACCCAGAGCAGCAAGTCTCGGCCGGATGGGATCCTCTGCATCCTAGGAATCGATAGCAGGTACAATGAAGGCTGCAGAGAGCTGGCAAATTATCTTCTATTTGGTTTGTACAATC
AGAATACCAGTGATTTTGAGAAAACGGGATTTTCTGAAGAAGTACTAGATGATGTAATTATATTGATTAAATCGGATAGCGTCCATCTGTACTGTAATCCTGTAAACTTTCGCTATCTCTTACCTTATGTGGCACATTGGAGAAATCTGC
ATTTCCACTGCATGACCGAAAATGAGTATGAAGATGAAGAAGCCGCAGAAGAATTTAAAATTACCAGCTTTGTGGACATGGTTCGAGACTGTAGTAGAATTGGCATTCCTTACAGCTCCCAAGGTCACTTGCAGATATTTGATATGTTTG
TGGTGGAGAAATGGCCAATTGTACAGGCCTTTGCACTTGAGGGCATTGGAGGGGATGGATTTTTTACCATGAAATATGAG

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Fusion Protein Sequence for C20orf194_TDRD10

In-frame Fusion Protein Sequences.

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499 length=432nt
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368482_3354694_154514499 length=491nt
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFIDNDDTVYLFVVNHPEFKNTVEIFKFEEAENSLLHLKTVKHELL
PSVNDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEK
PTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for C20orf194_TDRD10

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.H190Q_432_H271Q length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIQSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V192I_432_V273I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSIRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A137T;p.V192I_432_A218T;V273I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTTAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSIRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A137T;p.V192I_432_A218T;V273I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTTAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSIRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E126D_432_E207D length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLDKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P164R_432_P245R length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVRLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.M167T_432_M248T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLETRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.G194R_432_G275R length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRREAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R157M_432_R238M length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLMAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R193L_432_R274L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVLGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.L186Q_432_L267Q length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWQALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.G169V_432_G250V length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRVSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V204I_432_V285I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIIPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V192I_432_V273I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSIRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.L176P_432_L257P length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLPRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.S322L_432_S403L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSLYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R328Q_432_R409Q length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHQILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.S322L_432_S403L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSLYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A143T_432_A224T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLTPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E217K_432_E298K length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTKAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A288T_432_A369T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLTTIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R296C_432_R377C length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLCSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P312T_432_P393T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQTFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V204I_432_V285I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIIPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P147H_432_P228H length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAHVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E154D;p.S322L_432_E235D;S403L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETDKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSLYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.T201A_432_T282A length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVASIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R193L_432_R274L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVLGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.D302N_432_D383N length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDNFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.D283Y_432_D364Y length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIYFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E126D_432_E207D length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLDKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A128T_432_A209T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKTSGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.D301G_432_D382G length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSGDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.T201M_432_T282M length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVMSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.L309Q_432_L390Q length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPQTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R250H_432_R331H length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTHCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V192I_432_V273I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSIRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.V245I_432_V326I length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTIMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.G285R_432_G366R length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFRQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.D271N_432_D352N length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLNRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P205S_432_P286S length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVSKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E235K_432_E316K length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEKQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A143T_432_A224T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLTPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A137T_432_A218T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTTAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A143T_432_A224T length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLTPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R250H;p.R296H_432_R331H;R377H length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTHCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLHSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P205S_432_P286S length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVSKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.E195K;p.A196P_432_E276K;A277P length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGKPGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.R296H_432_R377H length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLHSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.P164L_432_P245L length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVLLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.A288V_432_A369V length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLVTIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.S170F_432_S251F length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGFFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

>C20orf194_TDRD10_ENST00000252032_ENST00000368480_3354694_154514499_3-gene_p.L188F_432_L269F length=432AA
MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITS
FVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYEVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLAFIHSVRGEAGLLVTSIVPKTPFFWAMHVTEAL
HQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSALHILKFEESK

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-09-2049-01D	3-gene	p.H190Q	432	H271Q
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-12-0707-01A	3-gene	p.V192I	432	V273I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-14-1034-01A	3-gene	p.A137T;p.V192I	432	A218T;V273I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-14-1034-02B	3-gene	p.A137T;p.V192I	432	A218T;V273I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-18-3416-01A	3-gene	p.E126D	432	E207D
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-34-5241-01A	3-gene	p.P164R	432	P245R
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-3A-A9IN-01A	3-gene	p.M167T	432	M248T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-3N-A9WC-06A	3-gene	p.G194R	432	G275R
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-46-3769-01A	3-gene	p.R157M	432	R238M
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-55-1596-01A	3-gene	p.R193L	432	R274L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-63-A5MP-01A	3-gene	p.L186Q	432	L267Q
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-78-7161-01A	3-gene	p.G169V	432	G250V
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-A5-A0G2-01A	3-gene	p.V204I	432	V285I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-A8-A09Q-01A	3-gene	p.V192I	432	V273I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AA-3947-01A	3-gene	p.L176P	432	L257P
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AA-3977-01A	3-gene	p.S322L	432	S403L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AA-3984-01A	3-gene	p.R328Q	432	R409Q
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AA-A00N-01A	3-gene	p.S322L	432	S403L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AA-A01X-01A	3-gene	p.A143T	432	A224T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AC-A23H-01A	3-gene	p.E217K	432	E298K
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AG-A002-01A	3-gene	p.A288T	432	A369T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AP-A056-01A	3-gene	p.R296C	432	R377C
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AR-A1AO-01A	3-gene	p.P312T	432	P393T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AX-A1CE-01A	3-gene	p.V204I	432	V285I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AX-A2HD-01A	3-gene	p.P147H	432	P228H
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-AZ-4315-01A	3-gene	p.E154D;p.S322L	432	E235D;S403L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-BR-4369-01A	3-gene	p.T201A	432	T282A
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-BR-8381-01A	3-gene	p.R193L	432	R274L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-BR-8680-01A	3-gene	p.D302N	432	D383N
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-BS-A0UF-01A	3-gene	p.D283Y	432	D364Y
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-BS-A0UV-01A	3-gene	p.E126D	432	E207D
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-CD-8531-01A	3-gene	p.A128T	432	A209T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-CM-6680-01A	3-gene	p.D301G	432	D382G
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-CQ-5324-01A	3-gene	p.T201M	432	T282M
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-DD-AAC8-01A	3-gene	p.L309Q	432	L390Q
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-DF-A2KZ-01A	3-gene	p.R250H	432	R331H
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-DU-8165-01A	3-gene	p.V192I	432	V273I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-E6-A2P9-01A	3-gene	p.V245I	432	V326I
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-EE-A2GC-06A	3-gene	p.G285R	432	G366R
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-EE-A2MD-06A	3-gene	p.D271N	432	D352N
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-EE-A2MS-06A	3-gene	p.P205S	432	P286S
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-EK-A3GM-01A	3-gene	p.E235K	432	E316K
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-EO-A22U-01A	3-gene	p.A143T	432	A224T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-F5-6814-01A	3-gene	p.A137T	432	A218T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-F7-A624-01A	3-gene	p.A143T	432	A224T
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-FI-A2D5-01A	3-gene	p.R250H;p.R296H	432	R331H;R377H
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-FR-A8YC-06A	3-gene	p.P205S	432	P286S
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-FS-A4F5-06A	3-gene	p.E195K;p.A196P	432	E276K;A277P
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-HU-A4GU-01A	3-gene	p.R296H	432	R377H
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-L5-A4OP-01A	3-gene	p.P164L	432	P245L
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-VQ-A8P2-01A	3-gene	p.A288V	432	A369V
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-WE-A8K4-01A	3-gene	p.S170F	432	S251F
ENST00000252032_ENST00000368480_3354694_154514499	TCGA-XF-A8HF-01A	3-gene	p.L188F	432	L269F

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for C20orf194_TDRD10

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		BRCA	TCGA-A2-A1FW-01A	C20orf194	chr20	3354694	-	TDRD10	chr1	3354694	+
ChimerDB		BRCA	TCGA-A2-A1FW	C20orf194	chr20	3354694	-	TDRD10	chr1	3354694	+
TCGAfusionPortal		BRCA	TCGA-A2-A1FW-01A	C20orf194	chr20	3354695	-	TDRD10	chr1	154514500	+
WashU		BRCA	TCGA-A2-A1FW-01A	C20orf194	chr20	3354695	-	TDRD10	chr1	154514500	+
cBioPortal	BRCA_TCGA_PAN_CAN_ATLAS_2018	BRCA	TCGA-A2-A1FW-01	C20ORF194	chr20	3374048		TDRD10	chr1	154542024

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for C20orf194_TDRD10

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status