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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:OLA1_CAB39 (FusionGDB2 ID:HG29789TG51719)

Fusion Gene Summary for OLA1_CAB39

Fusion gene summary

Fusion gene information	Fusion gene name: OLA1_CAB39
	Fusion gene ID: hg29789tg51719
		Hgene	Tgene
	Gene symbol	OLA1	CAB39
	Gene ID	29789	51719
	Gene name	Obg like ATPase 1	calcium binding protein 39
	Synonyms	DOC45\|GBP45\|GTBP9\|GTPBP9\|PTD004	CGI-66\|MO25
	Cytomap	2q31.1	2q37.1
	Type of gene	protein-coding	protein-coding
	Description	obg-like ATPase 1DNA damage-regulated overexpressed in cancer 45 proteinGTP-binding protein 9 (putative)GTP-binding protein PTD004homologous yeast-44.2 protein	calcium-binding protein 39MO25alpha
	Modification date	20240413	20240305
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000284719, ENST00000344357, ENST00000409546, ENST00000428402, ENST00000392560,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 16 X 16 X 14=3584	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 9 X 6=216
	# samples	27	8
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(27/358410)=-3.73053932500677 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(8/21610)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: OLA1 [Title/Abstract] AND CAB39 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	OLA1(174987907)-CAB39(231663443), # samples:1

Fusion gene breakpoints across OLA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CAB39 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for OLA1_CAB39

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
OLA1	chr2	174987907	CAB39	chr2	174987907
OLA1	chr2	174987908	CAB39	chr2	231663444
OLA1	chr2	174123180	CAB39	chr2	230798729

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for OLA1_CAB39

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	OLA1	GO:0046034	ATP metabolic process	17430889
Tgene	CAB39	GO:0007165	signal transduction	24393035
Tgene	CAB39	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	24393035
Tgene	CAB39	GO:0018105	peptidyl-serine phosphorylation	24393035
Tgene	CAB39	GO:0035556	intracellular signal transduction	24393035
Tgene	CAB39	GO:0071902	positive regulation of protein serine/threonine kinase activity	19892943\|24393035

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Fusion Genomic Features for OLA1_CAB39

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
OLA1	chr2	174987907	-	CAB39	chr2	231663443	+	5.75e-03	9.94e-01

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
OLA1	chr2	174987907	-	CAB39	chr2	231663443	+	5.75e-03	9.94e-01

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for OLA1_CAB39

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5UTR-3CDS	ENST00000392560	ENST00000258418	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
5UTR-3CDS	ENST00000392560	ENST00000409788	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
5UTR-3CDS	ENST00000392560	ENST00000410084	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000284719	ENST00000258418	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000284719	ENST00000409788	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000284719	ENST00000410084	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000428402	ENST00000258418	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000428402	ENST00000409788	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
Frame-shift	ENST00000428402	ENST00000410084	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000344357	ENST00000258418	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000344357	ENST00000409788	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000344357	ENST00000410084	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000409546	ENST00000258418	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000409546	ENST00000409788	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+
In-frame	ENST00000409546	ENST00000410084	OLA1	chr2	174987907	-	CAB39	chr2	231663443	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000344357	ENST00000258418	OLA1	chr2	174987907	CAB39	chr2	231663443	1.93e-03	9.98e-01
ENST00000344357	ENST00000409788	OLA1	chr2	174987907	CAB39	chr2	231663443	1.37e-03	9.99e-01
ENST00000344357	ENST00000410084	OLA1	chr2	174987907	CAB39	chr2	231663443	1.30e-03	9.99e-01
ENST00000409546	ENST00000258418	OLA1	chr2	174987907	CAB39	chr2	231663443	4.68e-04	1.00e+00
ENST00000409546	ENST00000409788	OLA1	chr2	174987907	CAB39	chr2	231663443	5.94e-04	9.99e-01
ENST00000409546	ENST00000410084	OLA1	chr2	174987907	CAB39	chr2	231663443	5.86e-04	9.99e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000392560	ENST00000258418	OLA1	chr2	174987907	CAB39	chr2	231663443	0.00e+00	1.05e-02
ENST00000392560	ENST00000409788	OLA1	chr2	174987907	CAB39	chr2	231663443	0.00e+00	6.01e-03
ENST00000392560	ENST00000410084	OLA1	chr2	174987907	CAB39	chr2	231663443	0.00e+00	4.20e-03

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for OLA1_CAB39

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

OLA1_CAB39_chr2-174987907_chr2-231663443.png

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

OLA1

chr2:174987907

chr2:231663443

ENST00000344357

Q9NTK5

23_283

84.66666666666667

239.0

Domain

OBG-type G

Hgene

OLA1

chr2:174987907

chr2:231663443

ENST00000344357

Q9NTK5

304_387

84.66666666666667

239.0

Domain

TGS

Hgene

OLA1

chr2:174987907

chr2:231663443

ENST00000344357

Q9NTK5

267_274

84.66666666666667

239.0

Motif

Nuclear export signal

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for OLA1_CAB39

In-frame Fusion Transcript Sequences.

>OLA1_CAB39_ENST00000344357_ENST00000258418_174987907_231663443 length=3774nt 
 Breakpoint=775nt
GTTCCGCCGCTGTCGCCGCCGTCGTGCGTGCCGCTCGGCGGAGGGGACGGGCCTGCGTTCTCTCCTCCTTCCTCCCCGCCTCCAGCTGCCGGCAGGACCTTTCTCTCGCTGCCGCTGGGACCCCGTGTCATCGCCCAGGCCGAGCACGGA
AATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAGGTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTC
CTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCATCTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACG
TTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGTGGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATA
TAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTTGACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAG
ACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAA
TGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGA
CAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCT
TTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCT
ATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTTAGCTATTCAGCATCAGGCACTCTTATTGATTCATGAGGAACATTACTGCTA
ATCTGCTGTTAAGTGAACGGTTTTTCATTTTACCCTTTTGTTTTTCAGTCCAGGTTGGAGATCGTAGCTGCTGCTGCTTGCACACTAGGGCACATGTGGGCTTTCTCTTGATCTTTGTGTCATTTCAGAATTCAAAGACTGTGCTACGGG
AGTTCTGAACATGGCTGGGTTCATGAAGGCAAATGTATGGATGAGAGTGTGGTTTAGGAAAGAGGGCACTGATATCAGATTAGACCTATGTGTTTGCACCCATCTTTGTTGGCGATCTGAGTGCAGTGTGGCAAGTGCACACCTGGCATC
CCTGCGTCAGATCGCGCACCTTCAGGTCGCGCACCTTCGCTGAAGGAAGATGACGCAGAGCTTTATCTGAAATCAGAGGGGAGCTATCCAAAATGGGAGTTTGGGGGCAGCTAAAGTTGACATGCGAATAAATTGATACTGAAACTTAGC
AACTTCTTAAAAGTGTAAAGAAGCCTCATAAGATCATAAGGAAAATGTATATATGCTTTTCACAGCTTTCTAGAATTTTTTGACATTTGATTTTCTTGAGACTTGTAAACCTGGATATGTTGAAGGGTATTTGTTAATTTTACTTTTCAA
AGATACTTTAAAACAGTAGAGCTAGCAATGACACCTTGCATTTCATTTCAACACTGCTTCAAGGTTTCTTTTGTATATAATTCTTAGAATGCTCATTTCTTTTAAATGGTTTAATTTGTACAGCAGAGGAATGTTATTGTAGTAGTATGT
AACTATTACCTAATACTGAGTTTTTGCAAAAAACAATGAATGCTCATATGTAATTGAAATACTTCAGATCACATGAAAATGCTGATTTAACATTTAAGTATCACAGCATTAAAAGAAAAAGAAAGTAAACCAGTCCTTTGTATTCAGTTA
CCTAATGGGGTGCCATCAATAAGCTGCGATACAGCCCTGGAGCTCAGTCAGCCACACCTTCCTGCATCCTATTGGCCTTATTCATTTTAAATGAGTTAATGAATCTGCCAGATCTGTGAATGATAGAGATTATGCTAAATTAATGCTGAT
TCTTTGTGTGTGTGGGAAATCTCTGTAGAGCACCTTTTCTTTCTTAGACTAAGTAACCCAGTACAATAGTTGTGAACTGAATAATTAAAACTTTGGCTTCTCTTAGGAAAAGACGACTTCCTAGTCATAGGTGTCCTATGGGGAAATTTA
TTTTTTTTAATGTCCTGTTCCTTAATGCTGCAAATTATCAGTATTTATAAAGTAACTGATTTTGCACCACTTTTTTGTTACTGTGACCACGGCAGAACAATGTCTTCTAGACTATATCTATGTAAAGTTATTAGAATGGTATCTGTTCAT
TTTAGTGATATGAAGATCACAACTAACAACTGACAAATCAGAGTTTGCCAGTTCAAATTCAGCATGGCTGCAGCTGATTAAGAAATTGATATGATTATTCTTTGCTAGCCTCTCTTACTAATGGAATTATATACTGGCCAGTAAAATGGG
CCTCCCAATTGCTGTTTCAGCAGGTTTTAAACCTTCAGGAACACCAGTTAGGAAAATAGCTCCAGAAAATATAGATATATTTTATTTTTATTAAAATGGCAGTCTACATCATAATTGGCATTTCTCAAGACTGTCTTTACCAGAATCTGT
GTGAAATAAGGCAATCTAGTCTCCTTGAAAAAAAAATCTCTTGGATGTTTAGGAAGGAAGACTTGGCCGTGATGTGGTGTCCTGGCTTTGTGGTGTAGTGCTGTGTGTATGGAGTTAGTGTAAAAACATGGATTACACCAAGTGGAAGAA
ACGTCTTCTTGCCAAGCTCATTCTTAGAACTTACACATCTAGAACAGCTTCCACTTTGGCAGTGAGGTCGTAGCCTTTTAGGTGGAAGAAGTGAGGGTGCAGCGTGTCAGACACAACATTCATGTTACTCTTACATTGGAATCTGAAGGT
AGTTCAGACTTCGTGGGTTTTGTTTTTAAGCAAAACAATGTGAAAACATTTAAGTTTGAAATGTTGCATTTGAAGTTATGATCATTTAATATATTCATATTACCAAGACTATTATACTGGAAGTGGTTTTTGTGTTATAAAGGTTTAATT
TTACATAAGGCAGTTACTTAATGTGATTTTTAACCCTTAAAAAAGTGGAGATGTATACATTTGTTAACAATGCCATGAAAGCATTTTCTTTCTCCTAAGGAAAAGTGAATTTCTTATCAGAATATCTGGCTGGCCCTGTAATTTAAATTA
AAATAAAATTTTGGAGAAACAGCA

>OLA1_CAB39_ENST00000344357_ENST00000409788_174987907_231663443 length=1449nt 
 Breakpoint=775nt
GTTCCGCCGCTGTCGCCGCCGTCGTGCGTGCCGCTCGGCGGAGGGGACGGGCCTGCGTTCTCTCCTCCTTCCTCCCCGCCTCCAGCTGCCGGCAGGACCTTTCTCTCGCTGCCGCTGGGACCCCGTGTCATCGCCCAGGCCGAGCACGGA
AATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAGGTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTC
CTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCATCTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACG
TTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGTGGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATA
TAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTTGACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAG
ACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAA
TGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGA
CAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCT
TTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCT
ATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTT

>OLA1_CAB39_ENST00000344357_ENST00000410084_174987907_231663443 length=1403nt 
 Breakpoint=775nt
GTTCCGCCGCTGTCGCCGCCGTCGTGCGTGCCGCTCGGCGGAGGGGACGGGCCTGCGTTCTCTCCTCCTTCCTCCCCGCCTCCAGCTGCCGGCAGGACCTTTCTCTCGCTGCCGCTGGGACCCCGTGTCATCGCCCAGGCCGAGCACGGA
AATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAGGTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTC
CTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCATCTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACG
TTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGTGGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATA
TAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTTGACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAG
ACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAA
TGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGA
CAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCT
TTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCT
ATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAA

>OLA1_CAB39_ENST00000409546_ENST00000258418_174987907_231663443 length=4418nt 
 Breakpoint=1419nt
AGTGGCCAAGATGGGGCCAGGGCAGCGGGTGGCTTGGGGATGTGTGGATGAATGAGGCGCTGTCGGACTAGGCCGCGCGTCGGGAGATCGGCCTACGCCTCACGCGGGAAAGCCCTGGGGAAAGCCTTCTCCCGACGCCAGGACGCCCGG
TGGCCCAGTCCGGAGAGGAGGATGGGGGGTGGGGCCCACTTTGGGTGGGCTGCCGGCCACCTCTCTGTAGGCCAGAGGACCCGACAGGCGCTGTTCCTGTATCTGTTCTTTGGAGGCCTGGGAGTTGGCCAGGAACAGGTGTCAGGACGC
TGAGAAGGGAAATTCCTGGCCCTCGGGGTCAGGGATCAGAGGCTGGAATACTACTGCAAGGGCAGGGCCCCAGCGTGGTCCTAGGAGGTACAACTCTCAGCCAGAAGACTGGGACAGTTTTAGTTCCCAGCTTCTGAGACGTGAGCTTAG
CGGTCTTTGTGATTTCACTTTGCAGTCCAAGGGTGGGAGTAATTCTGCACGCATGATTTGGAGACAGAACTAGTAAGGGACAGAGAAAGTTTCGACTTGTAAATAAAAAGGTTCCGTCGATTAATTTACCATTAGAAATAGTAACCATAA
TGTAGATTTTGGAGGTTGCTTATGAGGACTGATGAGCCGTACCTTCAGTGCCAAAGGTGGGAGGGACTTGGTGGAAGGACCCCAGTACCTGATGCCCCCTAAAAAGGGAGGTGATGGAATTAAACCACCCCCAATCATTGGAAGATTTGG
AACCTCACTGAAAATTGGTATTGTTGGATTGCCAAATGTTGGGAAATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAG
GTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTCCTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCAT
CTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACGTTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGT
GGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATATAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTT
GACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAGACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCAT
TTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATT
TTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGAT
GAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCA
GAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTTAGCTATT
CAGCATCAGGCACTCTTATTGATTCATGAGGAACATTACTGCTAATCTGCTGTTAAGTGAACGGTTTTTCATTTTACCCTTTTGTTTTTCAGTCCAGGTTGGAGATCGTAGCTGCTGCTGCTTGCACACTAGGGCACATGTGGGCTTTCT
CTTGATCTTTGTGTCATTTCAGAATTCAAAGACTGTGCTACGGGAGTTCTGAACATGGCTGGGTTCATGAAGGCAAATGTATGGATGAGAGTGTGGTTTAGGAAAGAGGGCACTGATATCAGATTAGACCTATGTGTTTGCACCCATCTT
TGTTGGCGATCTGAGTGCAGTGTGGCAAGTGCACACCTGGCATCCCTGCGTCAGATCGCGCACCTTCAGGTCGCGCACCTTCGCTGAAGGAAGATGACGCAGAGCTTTATCTGAAATCAGAGGGGAGCTATCCAAAATGGGAGTTTGGGG
GCAGCTAAAGTTGACATGCGAATAAATTGATACTGAAACTTAGCAACTTCTTAAAAGTGTAAAGAAGCCTCATAAGATCATAAGGAAAATGTATATATGCTTTTCACAGCTTTCTAGAATTTTTTGACATTTGATTTTCTTGAGACTTGT
AAACCTGGATATGTTGAAGGGTATTTGTTAATTTTACTTTTCAAAGATACTTTAAAACAGTAGAGCTAGCAATGACACCTTGCATTTCATTTCAACACTGCTTCAAGGTTTCTTTTGTATATAATTCTTAGAATGCTCATTTCTTTTAAA
TGGTTTAATTTGTACAGCAGAGGAATGTTATTGTAGTAGTATGTAACTATTACCTAATACTGAGTTTTTGCAAAAAACAATGAATGCTCATATGTAATTGAAATACTTCAGATCACATGAAAATGCTGATTTAACATTTAAGTATCACAG
CATTAAAAGAAAAAGAAAGTAAACCAGTCCTTTGTATTCAGTTACCTAATGGGGTGCCATCAATAAGCTGCGATACAGCCCTGGAGCTCAGTCAGCCACACCTTCCTGCATCCTATTGGCCTTATTCATTTTAAATGAGTTAATGAATCT
GCCAGATCTGTGAATGATAGAGATTATGCTAAATTAATGCTGATTCTTTGTGTGTGTGGGAAATCTCTGTAGAGCACCTTTTCTTTCTTAGACTAAGTAACCCAGTACAATAGTTGTGAACTGAATAATTAAAACTTTGGCTTCTCTTAG
GAAAAGACGACTTCCTAGTCATAGGTGTCCTATGGGGAAATTTATTTTTTTTAATGTCCTGTTCCTTAATGCTGCAAATTATCAGTATTTATAAAGTAACTGATTTTGCACCACTTTTTTGTTACTGTGACCACGGCAGAACAATGTCTT
CTAGACTATATCTATGTAAAGTTATTAGAATGGTATCTGTTCATTTTAGTGATATGAAGATCACAACTAACAACTGACAAATCAGAGTTTGCCAGTTCAAATTCAGCATGGCTGCAGCTGATTAAGAAATTGATATGATTATTCTTTGCT
AGCCTCTCTTACTAATGGAATTATATACTGGCCAGTAAAATGGGCCTCCCAATTGCTGTTTCAGCAGGTTTTAAACCTTCAGGAACACCAGTTAGGAAAATAGCTCCAGAAAATATAGATATATTTTATTTTTATTAAAATGGCAGTCTA
CATCATAATTGGCATTTCTCAAGACTGTCTTTACCAGAATCTGTGTGAAATAAGGCAATCTAGTCTCCTTGAAAAAAAAATCTCTTGGATGTTTAGGAAGGAAGACTTGGCCGTGATGTGGTGTCCTGGCTTTGTGGTGTAGTGCTGTGT
GTATGGAGTTAGTGTAAAAACATGGATTACACCAAGTGGAAGAAACGTCTTCTTGCCAAGCTCATTCTTAGAACTTACACATCTAGAACAGCTTCCACTTTGGCAGTGAGGTCGTAGCCTTTTAGGTGGAAGAAGTGAGGGTGCAGCGTG
TCAGACACAACATTCATGTTACTCTTACATTGGAATCTGAAGGTAGTTCAGACTTCGTGGGTTTTGTTTTTAAGCAAAACAATGTGAAAACATTTAAGTTTGAAATGTTGCATTTGAAGTTATGATCATTTAATATATTCATATTACCAA
GACTATTATACTGGAAGTGGTTTTTGTGTTATAAAGGTTTAATTTTACATAAGGCAGTTACTTAATGTGATTTTTAACCCTTAAAAAAGTGGAGATGTATACATTTGTTAACAATGCCATGAAAGCATTTTCTTTCTCCTAAGGAAAAGT
GAATTTCTTATCAGAATATCTGGCTGGCCCTGTAATTTAAATTAAAATAAAATTTTGGAGAAACAGCA

>OLA1_CAB39_ENST00000409546_ENST00000409788_174987907_231663443 length=2093nt 
 Breakpoint=1419nt
AGTGGCCAAGATGGGGCCAGGGCAGCGGGTGGCTTGGGGATGTGTGGATGAATGAGGCGCTGTCGGACTAGGCCGCGCGTCGGGAGATCGGCCTACGCCTCACGCGGGAAAGCCCTGGGGAAAGCCTTCTCCCGACGCCAGGACGCCCGG
TGGCCCAGTCCGGAGAGGAGGATGGGGGGTGGGGCCCACTTTGGGTGGGCTGCCGGCCACCTCTCTGTAGGCCAGAGGACCCGACAGGCGCTGTTCCTGTATCTGTTCTTTGGAGGCCTGGGAGTTGGCCAGGAACAGGTGTCAGGACGC
TGAGAAGGGAAATTCCTGGCCCTCGGGGTCAGGGATCAGAGGCTGGAATACTACTGCAAGGGCAGGGCCCCAGCGTGGTCCTAGGAGGTACAACTCTCAGCCAGAAGACTGGGACAGTTTTAGTTCCCAGCTTCTGAGACGTGAGCTTAG
CGGTCTTTGTGATTTCACTTTGCAGTCCAAGGGTGGGAGTAATTCTGCACGCATGATTTGGAGACAGAACTAGTAAGGGACAGAGAAAGTTTCGACTTGTAAATAAAAAGGTTCCGTCGATTAATTTACCATTAGAAATAGTAACCATAA
TGTAGATTTTGGAGGTTGCTTATGAGGACTGATGAGCCGTACCTTCAGTGCCAAAGGTGGGAGGGACTTGGTGGAAGGACCCCAGTACCTGATGCCCCCTAAAAAGGGAGGTGATGGAATTAAACCACCCCCAATCATTGGAAGATTTGG
AACCTCACTGAAAATTGGTATTGTTGGATTGCCAAATGTTGGGAAATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAG
GTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTCCTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCAT
CTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACGTTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGT
GGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATATAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTT
GACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAGACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCAT
TTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATT
TTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGAT
GAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCA
GAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTT

>OLA1_CAB39_ENST00000409546_ENST00000410084_174987907_231663443 length=2047nt 
 Breakpoint=1419nt
AGTGGCCAAGATGGGGCCAGGGCAGCGGGTGGCTTGGGGATGTGTGGATGAATGAGGCGCTGTCGGACTAGGCCGCGCGTCGGGAGATCGGCCTACGCCTCACGCGGGAAAGCCCTGGGGAAAGCCTTCTCCCGACGCCAGGACGCCCGG
TGGCCCAGTCCGGAGAGGAGGATGGGGGGTGGGGCCCACTTTGGGTGGGCTGCCGGCCACCTCTCTGTAGGCCAGAGGACCCGACAGGCGCTGTTCCTGTATCTGTTCTTTGGAGGCCTGGGAGTTGGCCAGGAACAGGTGTCAGGACGC
TGAGAAGGGAAATTCCTGGCCCTCGGGGTCAGGGATCAGAGGCTGGAATACTACTGCAAGGGCAGGGCCCCAGCGTGGTCCTAGGAGGTACAACTCTCAGCCAGAAGACTGGGACAGTTTTAGTTCCCAGCTTCTGAGACGTGAGCTTAG
CGGTCTTTGTGATTTCACTTTGCAGTCCAAGGGTGGGAGTAATTCTGCACGCATGATTTGGAGACAGAACTAGTAAGGGACAGAGAAAGTTTCGACTTGTAAATAAAAAGGTTCCGTCGATTAATTTACCATTAGAAATAGTAACCATAA
TGTAGATTTTGGAGGTTGCTTATGAGGACTGATGAGCCGTACCTTCAGTGCCAAAGGTGGGAGGGACTTGGTGGAAGGACCCCAGTACCTGATGCCCCCTAAAAAGGGAGGTGATGGAATTAAACCACCCCCAATCATTGGAAGATTTGG
AACCTCACTGAAAATTGGTATTGTTGGATTGCCAAATGTTGGGAAATCTACTTTCTTCAATGTGTTAACCAATAGTCAGGCTTCAGCAGAAAACTTCCCGTTCTGCACTATTGATCCTAATGAGAGCAGAGTACCTGTGCCAGATGAAAG
GTTTGACTTTCTTTGTCAATACCACAAACCAGCAAGCAAAATTCCTGCCTTTCTAAATGTGGTGGATATTGCTGGCCTTGTGAAAGGAGCTCACAATGGGCAGGGCCTGGGGAATGCTTTTTTATCTCATATTAGTGCCTGTGATGGCAT
CTTTCATCTAACACGTGCTTTTGAAGATGATGATATCACGCACGTTGAAGGAAGTGTAGATCCTATTCGAGATATAGAAATAATACATGAAGAGCTTCAGCTTAAAGATGAGGAAATGATTGGGCCCATTATAGATAAACTAGAAAAGGT
GGCTGTGAGAGGAGGAGATAAAAAACTAAAACCTGAATATGATATAATGTGCAAAGTAAAATCCTGGGTTATAGATCAAAAGAAACCTGTTCGCTTCTATCATGATTGGAATGACAAAGAGATTGAAGTGTTGAATAAACACTTATTTTT
GACTTCAAAACCAATGGTCTACTTGGTTAATCTTTCTGAAAAAGACTACATTAGAAAGAAAAACAAATGGTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCAT
TTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGATGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATT
TTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCTCGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGAT
GAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGCCAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCA
GAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTTGAAGAGACCAGCTCAGCAAGAAGCTTAA

N-Truncated Transcript (5UTR-3CDS) Sequences

>OLA1_CAB39_ENST00000392560_ENST00000258418_174987907_231663443 length=2999nt 
 Breakpoint=0nt
GTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGA
TGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCT
CGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGC
CAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTT
GAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTTAGCTATTCAGCATCAGGCACTCTTATTGATTCATGAGGAACATTACTGCTAATCTGCTGTTAAGTGAACGGTTTTT
CATTTTACCCTTTTGTTTTTCAGTCCAGGTTGGAGATCGTAGCTGCTGCTGCTTGCACACTAGGGCACATGTGGGCTTTCTCTTGATCTTTGTGTCATTTCAGAATTCAAAGACTGTGCTACGGGAGTTCTGAACATGGCTGGGTTCATG
AAGGCAAATGTATGGATGAGAGTGTGGTTTAGGAAAGAGGGCACTGATATCAGATTAGACCTATGTGTTTGCACCCATCTTTGTTGGCGATCTGAGTGCAGTGTGGCAAGTGCACACCTGGCATCCCTGCGTCAGATCGCGCACCTTCAG
GTCGCGCACCTTCGCTGAAGGAAGATGACGCAGAGCTTTATCTGAAATCAGAGGGGAGCTATCCAAAATGGGAGTTTGGGGGCAGCTAAAGTTGACATGCGAATAAATTGATACTGAAACTTAGCAACTTCTTAAAAGTGTAAAGAAGCC
TCATAAGATCATAAGGAAAATGTATATATGCTTTTCACAGCTTTCTAGAATTTTTTGACATTTGATTTTCTTGAGACTTGTAAACCTGGATATGTTGAAGGGTATTTGTTAATTTTACTTTTCAAAGATACTTTAAAACAGTAGAGCTAG
CAATGACACCTTGCATTTCATTTCAACACTGCTTCAAGGTTTCTTTTGTATATAATTCTTAGAATGCTCATTTCTTTTAAATGGTTTAATTTGTACAGCAGAGGAATGTTATTGTAGTAGTATGTAACTATTACCTAATACTGAGTTTTT
GCAAAAAACAATGAATGCTCATATGTAATTGAAATACTTCAGATCACATGAAAATGCTGATTTAACATTTAAGTATCACAGCATTAAAAGAAAAAGAAAGTAAACCAGTCCTTTGTATTCAGTTACCTAATGGGGTGCCATCAATAAGCT
GCGATACAGCCCTGGAGCTCAGTCAGCCACACCTTCCTGCATCCTATTGGCCTTATTCATTTTAAATGAGTTAATGAATCTGCCAGATCTGTGAATGATAGAGATTATGCTAAATTAATGCTGATTCTTTGTGTGTGTGGGAAATCTCTG
TAGAGCACCTTTTCTTTCTTAGACTAAGTAACCCAGTACAATAGTTGTGAACTGAATAATTAAAACTTTGGCTTCTCTTAGGAAAAGACGACTTCCTAGTCATAGGTGTCCTATGGGGAAATTTATTTTTTTTAATGTCCTGTTCCTTAA
TGCTGCAAATTATCAGTATTTATAAAGTAACTGATTTTGCACCACTTTTTTGTTACTGTGACCACGGCAGAACAATGTCTTCTAGACTATATCTATGTAAAGTTATTAGAATGGTATCTGTTCATTTTAGTGATATGAAGATCACAACTA
ACAACTGACAAATCAGAGTTTGCCAGTTCAAATTCAGCATGGCTGCAGCTGATTAAGAAATTGATATGATTATTCTTTGCTAGCCTCTCTTACTAATGGAATTATATACTGGCCAGTAAAATGGGCCTCCCAATTGCTGTTTCAGCAGGT
TTTAAACCTTCAGGAACACCAGTTAGGAAAATAGCTCCAGAAAATATAGATATATTTTATTTTTATTAAAATGGCAGTCTACATCATAATTGGCATTTCTCAAGACTGTCTTTACCAGAATCTGTGTGAAATAAGGCAATCTAGTCTCCT
TGAAAAAAAAATCTCTTGGATGTTTAGGAAGGAAGACTTGGCCGTGATGTGGTGTCCTGGCTTTGTGGTGTAGTGCTGTGTGTATGGAGTTAGTGTAAAAACATGGATTACACCAAGTGGAAGAAACGTCTTCTTGCCAAGCTCATTCTT
AGAACTTACACATCTAGAACAGCTTCCACTTTGGCAGTGAGGTCGTAGCCTTTTAGGTGGAAGAAGTGAGGGTGCAGCGTGTCAGACACAACATTCATGTTACTCTTACATTGGAATCTGAAGGTAGTTCAGACTTCGTGGGTTTTGTTT
TTAAGCAAAACAATGTGAAAACATTTAAGTTTGAAATGTTGCATTTGAAGTTATGATCATTTAATATATTCATATTACCAAGACTATTATACTGGAAGTGGTTTTTGTGTTATAAAGGTTTAATTTTACATAAGGCAGTTACTTAATGTG
ATTTTTAACCCTTAAAAAAGTGGAGATGTATACATTTGTTAACAATGCCATGAAAGCATTTTCTTTCTCCTAAGGAAAAGTGAATTTCTTATCAGAATATCTGGCTGGCCCTGTAATTTAAATTAAAATAAAATTTTGGAGAAACAGCA

>OLA1_CAB39_ENST00000392560_ENST00000409788_174987907_231663443 length=674nt 
 Breakpoint=0nt
GTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGA
TGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCT
CGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGC
CAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTT
GAAGAGACCAGCTCAGCAAGAAGCTTAATCTCCAATAAACATCTATGTTAAATCCAAATTCAGCATTTGCTGTT

>OLA1_CAB39_ENST00000392560_ENST00000410084_174987907_231663443 length=628nt 
 Breakpoint=0nt
GTATGAATCTCCAGAAATAGCTCTAAATTGTGGAATAATGTTAAGAGAATGCATCAGACATGAACCACTTGCAAAAATCATTTTGTGGTCGGAACAGTTTTATGATTTCTTCAGATATGTCGAAATGTCAACATTTGACATAGCTTCAGA
TGCATTTGCCACATTCAAGGATTTACTTACAAGACATAAATTGCTCAGTGCAGAATTTTTGGAACAGCATTATGATAGATTTTTCAGTGAATATGAGAAGTTACTTCATTCAGAAAATTATGTGACAAAAAGACAGTCACTGAAGCTTCT
CGGTGAACTACTACTAGATAGACACAACTTCACAATTATGACAAAATACATCAGTAAACCTGAGAACCTCAAATTAATGATGAACCTGCTGCGAGACAAAAGTCGCAACATCCAGTTTGAGGCCTTTCACGTTTTTAAGGTGTTTGTAGC
CAATCCTAACAAGACGCAGCCCATCCTAGACATCCTCCTCAAGAACCAGGCCAAACTCATAGAGTTCCTCAGCAAGTTTCAGAACGACAGGACGGAGGATGAGCAGTTTAACGACGAGAAGACCTATTTAGTTAAACAGATCAGGGATTT
GAAGAGACCAGCTCAGCAAGAAGCTTAA

C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for OLA1_CAB39

In-frame Fusion Protein Sequences.

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for OLA1_CAB39

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for OLA1_CAB39

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		CHOL	TCGA-W5-AA2U-01A	OLA1	chr2	174987907	-	CAB39	chr2	174987907	+
WashU		CHOL	TCGA-W5-AA2U-01A	OLA1	chr2	174987908	-	CAB39	chr2	231663444	+
cBioPortal	CHOL_TCGA_PAN_CAN_ATLAS_2018	CHOL	TCGA-W5-AA2U-01	OLA1	chr2	174123180		CAB39	chr2	230798729

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for OLA1_CAB39

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status