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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ARHGAP4-NUDT3 (FusionGDB2 ID:HG393TG11165) |
Fusion Gene Summary for ARHGAP4-NUDT3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARHGAP4-NUDT3 | Fusion gene ID: hg393tg11165 | Hgene | Tgene | Gene symbol | ARHGAP4 | NUDT3 | Gene ID | 393 | 11165 |
| Gene name | Rho GTPase activating protein 4 | nudix hydrolase 3 | |
| Synonyms | C1|RGC1|RhoGAP4|SrGAP4|p115 | DIPP|DIPP-1|DIPP1 | |
| Cytomap | ('ARHGAP4')('NUDT3') Xq28 | 6p21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rho GTPase-activating protein 4Rho-GAP hematopoietic protein C1rho-type GTPase-activating protein 4 | diphosphoinositol polyphosphate phosphohydrolase 1diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1nucleoside diphosphate-linked moiety X motif 3nudix (nucleoside diphosphate linked moiety X)-type motif 3nudix motif 3 | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000537206, ENST00000350060, ENST00000370016, ENST00000370028, ENST00000393721, ENST00000467421, | ||
| Fusion gene scores | * DoF score | 3 X 5 X 3=45 | 13 X 7 X 8=728 |
| # samples | 6 | 15 | |
| ** MAII score | log2(6/45*10)=0.415037499278844 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(15/728*10)=-2.27897594970282 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARHGAP4 [Title/Abstract] AND NUDT3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ARHGAP4(153179232)-NUDT3(34309749), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | ARHGAP4-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGAP4-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGAP4-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGAP4-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGAP4-NUDT3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NUDT3 | GO:0071544 | diphosphoinositol polyphosphate catabolic process | 10585413 |
| Fusion gene breakpoints across ARHGAP4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across NUDT3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-02-2485-01A | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
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Fusion Gene ORF analysis for ARHGAP4-NUDT3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000537206 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| In-frame | ENST00000350060 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| In-frame | ENST00000370016 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| In-frame | ENST00000370028 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| In-frame | ENST00000393721 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| intron-3CDS | ENST00000467421 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000393721 | ARHGAP4 | chrX | 153179232 | - | ENST00000607016 | NUDT3 | chr6 | 34309749 | - | 10146 | 652 | 52 | 1071 | 339 |
| ENST00000370028 | ARHGAP4 | chrX | 153179232 | - | ENST00000607016 | NUDT3 | chr6 | 34309749 | - | 10806 | 1312 | 58 | 1731 | 557 |
| ENST00000350060 | ARHGAP4 | chrX | 153179232 | - | ENST00000607016 | NUDT3 | chr6 | 34309749 | - | 10670 | 1176 | 42 | 1595 | 517 |
| ENST00000370016 | ARHGAP4 | chrX | 153179232 | - | ENST00000607016 | NUDT3 | chr6 | 34309749 | - | 10607 | 1113 | 42 | 1532 | 496 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000393721 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - | 0.000733013 | 0.99926704 |
| ENST00000370028 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - | 0.000464581 | 0.99953544 |
| ENST00000350060 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - | 0.000381929 | 0.99961805 |
| ENST00000370016 | ENST00000607016 | ARHGAP4 | chrX | 153179232 | - | NUDT3 | chr6 | 34309749 | - | 0.000605918 | 0.99939406 |
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Fusion Genomic Features for ARHGAP4-NUDT3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ARHGAP4-NUDT3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:153179232/chr6:34309749) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000350060 | - | 8 | 22 | 128_195 | 378 | 947.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000370028 | - | 9 | 23 | 128_195 | 418 | 987.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000350060 | - | 8 | 22 | 19_317 | 378 | 947.0 | Domain | F-BAR |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000370028 | - | 9 | 23 | 19_317 | 418 | 987.0 | Domain | F-BAR |
| Tgene | NUDT3 | chrX:153179232 | chr6:34309749 | ENST00000607016 | 0 | 5 | 51_72 | 33 | 173.0 | Motif | Note=Nudix box | |
| Tgene | NUDT3 | chrX:153179232 | chr6:34309749 | ENST00000607016 | 0 | 5 | 39_41 | 33 | 173.0 | Region | Substrate binding | |
| Tgene | NUDT3 | chrX:153179232 | chr6:34309749 | ENST00000607016 | 0 | 5 | 89_91 | 33 | 173.0 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000350060 | - | 8 | 22 | 507_695 | 378 | 947.0 | Domain | Rho-GAP |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000350060 | - | 8 | 22 | 746_805 | 378 | 947.0 | Domain | SH3 |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000370028 | - | 9 | 23 | 507_695 | 418 | 987.0 | Domain | Rho-GAP |
| Hgene | ARHGAP4 | chrX:153179232 | chr6:34309749 | ENST00000370028 | - | 9 | 23 | 746_805 | 418 | 987.0 | Domain | SH3 |
| Tgene | NUDT3 | chrX:153179232 | chr6:34309749 | ENST00000607016 | 0 | 5 | 17_142 | 33 | 173.0 | Domain | Nudix hydrolase | |
| Tgene | NUDT3 | chrX:153179232 | chr6:34309749 | ENST00000607016 | 0 | 5 | 18_20 | 33 | 173.0 | Region | Substrate binding |
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Fusion Gene Sequence for ARHGAP4-NUDT3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >6133_6133_1_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000350060_NUDT3_chr6_34309749_ENST00000607016_length(transcript)=10670nt_BP=1176nt CGTGGGAGCAGTGGGGTTCGACGGCGCGGCCGCGAGGCCGCCATGGCCGCTCACGGGAAGCTGCGGCGGGAGCGGGGGCTGCAGGCTGAG TATGAGACGCAAGTCAAAGAGATGCGCTGGCAGCTGAGCGAGCAGCTGCGCTGCCTGGAGCTGCAGGGCGAGCTGCGGCGGGAGTTGCTG CAGGAGCTGGCAGAGTTCATGCGGCGCCGCGCTGAGGTGGAGCTGGAATACTCCCGGGGCCTGGAAAAGCTGGCCGAGCGCTTCTCCAGC CGTGGAGGCCGCCTGGGGAGCAGCCGGGAGCACCAAAGCTTCCGGAAGGAGCCGTCCCTCCTGTCGCCCTTGCACTGCTGGGCGGTGCTG CTGCAGCACACGCGGCAGCAGAGCCGGGAGAGCGCGGCCCTGAGTGAGGTGCTGGCCGGGCCCCTGGCCCAGCGCCTGAGTCACATTGCA GAGGACGTGGGGCGCCTGGTCAAGAAGAGCAGGGATCTGGAGCAGCAGCTGCAGGATGAGCTCCTGGAGGTGGTCTCAGAGCTCCAGACG GCCAAGAAGACGTACCAGGCATATCACATGGAGAGCGTGAATGCCGAGGCCAAGCTCCGGGAGGCCGAGCGGCAGGAGGAGAAGCGGGCA GGCCGGAGTGTCCCCACCACCACCGCTGGTGCCACTGAGGCAGGGCCCCTCCGCAAGAGCTCCCTCAAGAAGGGAGGGAGGCTGGTGGAG AAGCGGCAGGCCAAGTTCATGGAGCACAAACTCAAGTGCACAAAGGCGCGCAACGAGTACCTGCTTAGCCTGGCTAGTGTCAACGCTGCT GTCAGTAACTACTACCTGCATGACGTCTTGGACCTCATGGACTGCTGTGACACAGGGTTCCACCTGGCCCTGGGGCAGGTGCTCCGGAGC TACACGGCCGCTGAGAGCCGCACCCAAGCCTCCCAAGTGCAGGGCCTGGGCAGCCTGGAAGAAGCTGTGGAGGCCCTGGATCCTCCAGGG GACAAAGCCAAGGTTCTCGAGGTGCATGCTACCGTCTTCTGTCCCCCGCTGCGCTTTGACTACCACCCCCATGATGGGGATGAGGTGGCT GAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGCCGCCTGGACCGACAGACCATTGAGACA GAGGAGGTGCTACTCGTGAGCAGTAGTCGCCATCCAGACAGATGGATTGTCCCTGGAGGAGGCATGGAGCCCGAGGAGGAGCCAAGTGTG GCAGCAGTTCGTGAAGTCTGTGAGGAGGCTGGAGTAAAAGGGACATTGGGAAGATTAGTTGGAATTTTTGAGAACCAGGAGAGGAAGCAC AGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGACTGGGAAGATTCAGTTAACATTGGAAGGAAGAGGGAATGGTTTAAA ATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCAGGCATCATATTTTGAAACATTGAGGCAAGGCTACTCAGCCAACAAT GGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAGCTCGATGTCAGGCATCAGATGACTGAAGACTTCCTGTAAGAGAAAT GGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCCTGGCTCTTTCCACTTCTCACAGGCCTCCTCTTTCAAATAAGGCATG GTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGTGTTAAGTGATGGGGCTTTTTCTTCTGTTTTTATTGAGGGTGGGGGT TGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTCCCTCTTCCCACCCCTGCAGTCCTCTGAAGAGAGGCCAACAGCCTTC CCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGCCCTGGCCAGACGTTTTCTTTGATTTTTAATTTTTTTTTTTTATTAA AAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATAATGTGCTGTACAGTTCAGTAGAGTGGTCACTTTCACTGCAGTATAC ATTTATCTACACATTATATATCGGACATATAATATGTAAATAAATGACTTCTAGAAAGAGAAATTTGTTTAATTTTTCAAGGTTTTTTTC TCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAACATACCTTTTTGTTTTCGATGCTAGTGGCTGGGCAGGTTGCCCTGT CCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGTTTAGCTACCTTCATAGTGCTCCCAGGACTCATGGCCTTTCCTTCTT TAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTTTTTTATTTTTTTATTTTTTTTTAACCAAGCAAGGAGCAAATGGCCT CAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCCCACATGTTGACAGTAGAGTTGGAACTGGATTCTTGGGATTACTTAT CTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTGGAATCTTTTCCGTAATGCTATTTATTGCCAACAATGGCCTCTCTTT GTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCATGTGCTCTGAAGCATCCAACTTTACTTTGCAGGTGCATCAATGTAG TCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTAGGGAAATTCACCTGCTTGCTTGTCTTTGTATTGGCATGGCACTTGT GATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCCATCTCCCACCAGGATATGAAAGGTCCATATGGGAGGCCACGTAATC ACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTCTCTTGTTTTTTGATACAGTTTCGTGCTGGCTTCATTTGCCAATTGT GTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAGGGAGGGCTACACTGACTGATCCGTGGCTTAAGACAGGAGATTATCT CTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAATCATAGTTCGCCTCATTTAAAAATTCTAATAAAGCACTCAAACTTT GAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTACCTCATAGCCCTGTGTCATTTAGTGTTCAGCACTTTTGGGAACATCA GTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGA TCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATGCAGAAATTAGGTGGGCGCCTGTA ATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGTCGTCC AGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAAAATTTTTTTTTTTTTTTTTGCTATATACTCTTAGTTTACATCC TCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTCTTGGGATACCATGATACCTCTGGGAAAGGAATTATATTCCCAAGGA GAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGAATGCCAACTTACTATTCACACATCCTTCTTAAAAACGAACACACTG TTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAAATAAAGGGCAAAATAAAGTAGATTTAACCAAGTGCCAGGTGGAATT CAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGGATTTGAAAGTACTTTGCAGGAAAACAGTCAGTACTCTTTAAAAAGG GACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGGTCACTTGAGGCCAGGAGTTTGA GACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGGCATGATGGTGCACTCCTGTAATCCCAGCTAC TTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCAA CAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACGGAACTGCAGTGCTAACAGTAATTTATACATTTTTAAATGTTCTGAG TATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGTGCAGTTTTGATTGTTGTTGGTGTCTTTGGGTCAGGAAAGTGAACTG TGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAATGCAATTGACTGAGAGATTGTGCTTACGCTTTCTTAACTGACAAAAA GAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTTCTGTTGCACTGGGATTCTGATGATCTGGGATTTTCCCTCCTTGGCA CAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTCCTTTAGTGATAGATTAGTTAGACCCATGGTTGCAATACCTTTATCT CCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTTTGCAGAATATTTCACTGACATTGATTTGTCATTAATTCTACCAGAG CTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGGGCAGATCCCTAGCCTCTCGCTCACAGTGAGTCTGCATGTCCTAGAT TCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGGACAGAAGAAGATAGCAGTGGATTTGTAAAAATTTTTAGTTTATAAA TTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTGGACCAGGATTTTCTCTCTGTCTTCTCTCTGGGTGTGTGTGTGTGTA TGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTCTGTAGTCTTCCAGAAACAGTGCAGCCCATACAACAGGAATCTTAAT TTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTGTTTTCACAAGTGTCCACCACTCCATCTGCCCTGCATGGAGAGGGCT CTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAGGGTGTGGGAGTATCACCCCCTCTCAGGCTGCAGAAGGTCTCGAGGG TGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAGCCCCATGGAACATGAGGCACTTGAGGCCTTGCTTCTTGGAGCCTCT GGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTAGTTTTGTAAATGTGTTGCTACATAGTCAAGTTCCTTTGTGGCAAAG AAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTCTCAGGCTTGCTTGCTTAGAAGAAAAAAGTCACCCTTTGTGGTTTTT AAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTCCCTTTTCTCTACATACAGTGCTCATTGGAGGCTCCTGCTAAACCTT CTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACATTTCACATGTTATCCTTCACATATTTCTCATTTTCATCTAGTACTT TCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAAAAAAAAAAAAAACAGCTTAGCCTAAGCCACATTCACTTTTTTTAGT TCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAACTGTGTGATTTTAATATTCTCTAATATCAAGGGCGGATTTAGAATTG CAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTTAAGAGAAATGAGAGTTGGCTGTCTCTGTAATTGATAATACAGCTTC ATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTACAAAACACAGGACACTTGTGGGACAGTTAACTCAAGCAGCTATGGGG AGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTCTTCTGTTTCTTAAAGACTGTGGAAGAGGTCAGACTGCCCAGTTGAG GTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTCTGAGTCCTGTTGGATAGAGCCTATCTCCTCAAGGCTACAGAGGCTT CCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCCATCAGGGCACCTGCCTAACTTGGAGCAAGTGGGAGAGCACCCTAGA GTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCACCATCCGGAGGAGCTGTGTTTCTGTGTCACTTGGGATATCACCTAA AAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATTGGGGAACATTGGCTGCAGTCCCTAAAAGATACTGTTGTCTGTGCAT CAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGTTTAGGCATACTCTCCTTTGGAGGCCAGCAGCCTTTCACAAACCCTG CCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAGCCTCAGAAACTCTTGTCTTTAGCTGATAACCTTTGAGGGATGTGAG AAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCAAATTAATCAAATAGTTTGTCCTTCTAGTCCCCTTATAAATTAATAA ATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACAAGGTCAGGAGTTCAAGACC AGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGTGGCACGCTCCTGTAGTCCCAGCTACTCG GGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGTTGCAGTGAGCCGAGATCCCGCCACTGCACTGCAGCCTAGGCGACAG AGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGGAAGGGAATCCCATTTTGTGATGATTTGGGCACACTACTTGAGCTGA GGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTTTGAAGTAAGGTTATGTCTCTTCCCTGAAGCTTTGTTTATAGTGGTA ATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACTGTCCACCTGGGGAGGGGAGCTTATAGGGAACCCGTGTTAACTCAGA ATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTATCTAGAAGGTGGAAAGAAGTCATTGCTTCTGTTCCTCCAGCAGTCAG TTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATACTAAAACTTATTTGACTTCCTATCAGGAAGCACACAAAAAAAGCGTC ATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCAGCATTGTCGTTTTGCCAGGTTCATCACCATTTTGATGTGCTACCCA TCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGCCAGATGTGAAGATTCTATTAATCACTGTTTCAGAGAACATTAATTC TTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACTACCTTGCAGAGAACATCTCAACAGTGCAGTAAAATAGCTCTCCTAG ACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTGTGGAATTCTGAGGAAAAAAAGCAAGATGCCTCAATGCCAATGCTGG GCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGCTCAGCTTTGGAAAATCATTTTGCCAGTAATATTGCCTGTGAATCCC TTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTTGGTGCTGAATTGAAAATGGTAAGCTAAAGCAGTGACAGATCCACGT AGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCTCAGGTTAAACCTTTGTCTTTAACCTCCCTTTGTTGTGGAGAAAATG TGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTCAGTTCCTGCAGCATAACAGATATGACTTATGCCAGGGAAGGTAGAG GCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGGTCTGCTCCACGTAGAACCTCCCCAGATCGGAAGTTAAGTCTTGGAG AGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTTGCTTAATGAGCAAGAGGCTTGTGTCCTCCCAAGAACATGAGGGAGT TCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCACCCCATCCCTCGTGACTGGGAGCATGTTTGCTCAGAATTTTCTAAGA GGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTTAGCCTCTGAGAATCTCACTCTTTCATTTCCATCTGTGAATGGACAT AGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCAGTGGCATGGTGTTGCATTAGTAGTTAGAAAAGTAATTGGTCAGCTC TACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCAGGTCTGTTCTATTGTTTTGTGATCTGAAGACTGTCAAACTGGTTGA TAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGTTAGAAAGATATAGCTTACCAGTTTTCCATGTGCTTAAGGAAGTCAA GAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAGCTAGTGTCTCTCACCTTCTTAGGTGTATCAGAGAGAGGAAGTGGAA GGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCTCCATTTCAAAGACTTTGTCTTCCATCCTATCCAATGACATGGTCAG GGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTCCACTGTGGTGTGTAGTCTCCAAACAGCTTAAGGGTTTTTAAGTTTT CTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAAAGGTTAACATCCCTGGGACCATTCTACTTATAAAAGAGATGAACTA GTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATCTCCTCTTGGCCAAGTTCAACAAATGTTTCCAGGGAACCCCGTGGGT TGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAGGACAAAAGTATTTCTTGTCCCTTTTCCCTCATGCTCATATGTTTTA GCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGAGACAGAGAGCCAGGGACCCATGTACCCAGGGACCAGTCCCCTGGGG AATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAACTCTGCTGCTGTTCATTTCCATCAGGACCACCCAGGAAAGCAAATAA GTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAGGATGAGAGCATATATAGATCTCCTGTTTAGAGAGTGTGTTCATAAT TGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCATTTTTTAAGAGGATGGCAAGGATGACCTCAAATGAGCTCAACAAAAC TGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTTGTGGTCCTTAAACCTCTTGGCACCTTGTGCGGGTTATAAAACAAGG AGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCAGGATTTAGGAGCTACCCAACCTGTGGTTATATGGTGTTGGTTTCCA TTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTACTGCATGGAAAGTTCAAGCTTTTCTTCTTGCCCGCTCAGGGCTGGCC TCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAGCACTCTCTGGAGCTGAGGGGAGTGAAATTTGGTCCAGAGAAGGCGG AAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCTCAGGCTTCCTTCACACCTCCTTCTCATGGGTGCGGCTGGCAGTACA GTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCAGCCCCAGGTTTGGTCTGAGACAGGTACACAGCAGATACCATCCCAC CTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCCCTACTTTACTAATGTATCCCTTATGTGGTACCAGCAATGGAGGACA GGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACCCGTAAAACTTGACCACCCCCATATCCCACTCCTTTTTGTAAAAACA AATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAATCAGTTTCCTTCCATTTGAGCTGTGTGGGAGGGAAGGGCATTGAAAT >6133_6133_1_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000350060_NUDT3_chr6_34309749_ENST00000607016_length(amino acids)=517AA_BP=378 MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSF RKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTAKKTYQAYHMESVN AEAKLREAERQEEKRAGRSVPTTTAGATEAGPLRKSSLKKGGRLVEKRQAKFMEHKLKCTKARNEYLLSLASVNAAVSNYYLHDVLDLMD CCDTGFHLALGQVLRSYTAAESRTQASQVQGLGSLEEAVEALDPPGDKAKVLEVHATVFCPPLRFDYHPHDGDEVAEICVEMELRDEILP RAQNIQSRLDRQTIETEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLE -------------------------------------------------------------- >6133_6133_2_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000370016_NUDT3_chr6_34309749_ENST00000607016_length(transcript)=10607nt_BP=1113nt CGTGGGAGCAGTGGGGTTCGACGGCGCGGCCGCGAGGCCGCCATGGCCGCTCACGGGAAGCTGCGGCGGGAGCGGGGGCTGCAGGCTGAG TATGAGACGCAAGTCAAAGAGATGCGCTGGCAGCTGAGCGAGCAGCTGCGCTGCCTGGAGCTGCAGGGCGAGCTGCGGCGGGAGTTGCTG CAGGAGCTGGCAGAGTTCATGCGGCGCCGCGCTGAGGTGGAGCTGGAATACTCCCGGGGCCTGGAAAAGCTGGCCGAGCGCTTCTCCAGC CGTGGAGGCCGCCTGGGGAGCAGCCGGGAGCACCAAAGCTTCCGGAAGGAGCCGTCCCTCCTGTCGCCCTTGCACTGCTGGGCGGTGCTG CTGCAGCACACGCGGCAGCAGAGCCGGGAGAGCGCGGCCCTGAGTGAGGTGCTGGCCGGGCCCCTGGCCCAGCGCCTGAGTCACATTGCA GAGGACGTGGGGCGCCTGGTCAAGAAGGCCAAGAAGACGTACCAGGCATATCACATGGAGAGCGTGAATGCCGAGGCCAAGCTCCGGGAG GCCGAGCGGCAGGAGGAGAAGCGGGCAGGCCGGAGTGTCCCCACCACCACCGCTGGTGCCACTGAGGCAGGGCCCCTCCGCAAGAGCTCC CTCAAGAAGGGAGGGAGGCTGGTGGAGAAGCGGCAGGCCAAGTTCATGGAGCACAAACTCAAGTGCACAAAGGCGCGCAACGAGTACCTG CTTAGCCTGGCTAGTGTCAACGCTGCTGTCAGTAACTACTACCTGCATGACGTCTTGGACCTCATGGACTGCTGTGACACAGGGTTCCAC CTGGCCCTGGGGCAGGTGCTCCGGAGCTACACGGCCGCTGAGAGCCGCACCCAAGCCTCCCAAGTGCAGGGCCTGGGCAGCCTGGAAGAA GCTGTGGAGGCCCTGGATCCTCCAGGGGACAAAGCCAAGGTTCTCGAGGTGCATGCTACCGTCTTCTGTCCCCCGCTGCGCTTTGACTAC CACCCCCATGATGGGGATGAGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGC CGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGCTACTCGTGAGCAGTAGTCGCCATCCAGACAGATGGATTGTCCCTGGAGGAGGC ATGGAGCCCGAGGAGGAGCCAAGTGTGGCAGCAGTTCGTGAAGTCTGTGAGGAGGCTGGAGTAAAAGGGACATTGGGAAGATTAGTTGGA ATTTTTGAGAACCAGGAGAGGAAGCACAGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGACTGGGAAGATTCAGTTAAC ATTGGAAGGAAGAGGGAATGGTTTAAAATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCAGGCATCATATTTTGAAACA TTGAGGCAAGGCTACTCAGCCAACAATGGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAGCTCGATGTCAGGCATCAGA TGACTGAAGACTTCCTGTAAGAGAAATGGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCCTGGCTCTTTCCACTTCTCA CAGGCCTCCTCTTTCAAATAAGGCATGGTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGTGTTAAGTGATGGGGCTTTT TCTTCTGTTTTTATTGAGGGTGGGGGTTGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTCCCTCTTCCCACCCCTGCAG TCCTCTGAAGAGAGGCCAACAGCCTTCCCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGCCCTGGCCAGACGTTTTCTT TGATTTTTAATTTTTTTTTTTTATTAAAAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATAATGTGCTGTACAGTTCAGT AGAGTGGTCACTTTCACTGCAGTATACATTTATCTACACATTATATATCGGACATATAATATGTAAATAAATGACTTCTAGAAAGAGAAA TTTGTTTAATTTTTCAAGGTTTTTTTCTCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAACATACCTTTTTGTTTTCGA TGCTAGTGGCTGGGCAGGTTGCCCTGTCCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGTTTAGCTACCTTCATAGTGC TCCCAGGACTCATGGCCTTTCCTTCTTTAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTTTTTTATTTTTTTATTTTTT TTTAACCAAGCAAGGAGCAAATGGCCTCAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCCCACATGTTGACAGTAGAGT TGGAACTGGATTCTTGGGATTACTTATCTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTGGAATCTTTTCCGTAATGCT ATTTATTGCCAACAATGGCCTCTCTTTGTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCATGTGCTCTGAAGCATCCAA CTTTACTTTGCAGGTGCATCAATGTAGTCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTAGGGAAATTCACCTGCTTGC TTGTCTTTGTATTGGCATGGCACTTGTGATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCCATCTCCCACCAGGATATGA AAGGTCCATATGGGAGGCCACGTAATCACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTCTCTTGTTTTTTGATACAGT TTCGTGCTGGCTTCATTTGCCAATTGTGTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAGGGAGGGCTACACTGACTGA TCCGTGGCTTAAGACAGGAGATTATCTCTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAATCATAGTTCGCCTCATTTA AAAATTCTAATAAAGCACTCAAACTTTGAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTACCTCATAGCCCTGTGTCATT TAGTGTTCAGCACTTTTGGGAACATCAGTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTGGCTCACACCTGTAATCCCA GCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAAA AATGCAGAAATTAGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACCTGGGAGGCAGAGGTTGCAG TGAGCCGAGATTGCACCACTGTCGTCCAGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAAAATTTTTTTTTTTTTT TTTGCTATATACTCTTAGTTTACATCCTCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTCTTGGGATACCATGATACCT CTGGGAAAGGAATTATATTCCCAAGGAGAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGAATGCCAACTTACTATTCAC ACATCCTTCTTAAAAACGAACACACTGTTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAAATAAAGGGCAAAATAAAGT AGATTTAACCAAGTGCCAGGTGGAATTCAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGGATTTGAAAGTACTTTGCAG GAAAACAGTCAGTACTCTTTAAAAAGGGACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAG GTGGGTCACTTGAGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGGCATG ATGGTGCACTCCTGTAATCCCAGCTACTTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGAT CATGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACGGAACTGCAGTGCTAACAGT AATTTATACATTTTTAAATGTTCTGAGTATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGTGCAGTTTTGATTGTTGTTG GTGTCTTTGGGTCAGGAAAGTGAACTGTGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAATGCAATTGACTGAGAGATTG TGCTTACGCTTTCTTAACTGACAAAAAGAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTTCTGTTGCACTGGGATTCTG ATGATCTGGGATTTTCCCTCCTTGGCACAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTCCTTTAGTGATAGATTAGTT AGACCCATGGTTGCAATACCTTTATCTCCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTTTGCAGAATATTTCACTGAC ATTGATTTGTCATTAATTCTACCAGAGCTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGGGCAGATCCCTAGCCTCTCG CTCACAGTGAGTCTGCATGTCCTAGATTCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGGACAGAAGAAGATAGCAGTG GATTTGTAAAAATTTTTAGTTTATAAATTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTGGACCAGGATTTTCTCTCTG TCTTCTCTCTGGGTGTGTGTGTGTGTATGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTCTGTAGTCTTCCAGAAACAG TGCAGCCCATACAACAGGAATCTTAATTTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTGTTTTCACAAGTGTCCACCA CTCCATCTGCCCTGCATGGAGAGGGCTCTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAGGGTGTGGGAGTATCACCCC CTCTCAGGCTGCAGAAGGTCTCGAGGGTGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAGCCCCATGGAACATGAGGCA CTTGAGGCCTTGCTTCTTGGAGCCTCTGGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTAGTTTTGTAAATGTGTTGCT ACATAGTCAAGTTCCTTTGTGGCAAAGAAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTCTCAGGCTTGCTTGCTTAGA AGAAAAAAGTCACCCTTTGTGGTTTTTAAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTCCCTTTTCTCTACATACAGT GCTCATTGGAGGCTCCTGCTAAACCTTCTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACATTTCACATGTTATCCTTCA CATATTTCTCATTTTCATCTAGTACTTTCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAAAAAAAAAAAAAACAGCTTA GCCTAAGCCACATTCACTTTTTTTAGTTCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAACTGTGTGATTTTAATATTCT CTAATATCAAGGGCGGATTTAGAATTGCAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTTAAGAGAAATGAGAGTTGGC TGTCTCTGTAATTGATAATACAGCTTCATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTACAAAACACAGGACACTTGTG GGACAGTTAACTCAAGCAGCTATGGGGAGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTCTTCTGTTTCTTAAAGACTG TGGAAGAGGTCAGACTGCCCAGTTGAGGTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTCTGAGTCCTGTTGGATAGAG CCTATCTCCTCAAGGCTACAGAGGCTTCCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCCATCAGGGCACCTGCCTAAC TTGGAGCAAGTGGGAGAGCACCCTAGAGTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCACCATCCGGAGGAGCTGTGT TTCTGTGTCACTTGGGATATCACCTAAAAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATTGGGGAACATTGGCTGCAGT CCCTAAAAGATACTGTTGTCTGTGCATCAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGTTTAGGCATACTCTCCTTTG GAGGCCAGCAGCCTTTCACAAACCCTGCCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAGCCTCAGAAACTCTTGTCTT TAGCTGATAACCTTTGAGGGATGTGAGAAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCAAATTAATCAAATAGTTTGT CCTTCTAGTCCCCTTATAAATTAATAAATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGT GGATCACAAGGTCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGTG GCACGCTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGTTGCAGTGAGCCGAGATCCC GCCACTGCACTGCAGCCTAGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGGAAGGGAATCCCATTTTGTG ATGATTTGGGCACACTACTTGAGCTGAGGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTTTGAAGTAAGGTTATGTCTC TTCCCTGAAGCTTTGTTTATAGTGGTAATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACTGTCCACCTGGGGAGGGGAG CTTATAGGGAACCCGTGTTAACTCAGAATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTATCTAGAAGGTGGAAAGAAGT CATTGCTTCTGTTCCTCCAGCAGTCAGTTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATACTAAAACTTATTTGACTTCC TATCAGGAAGCACACAAAAAAAGCGTCATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCAGCATTGTCGTTTTGCCAGG TTCATCACCATTTTGATGTGCTACCCATCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGCCAGATGTGAAGATTCTATT AATCACTGTTTCAGAGAACATTAATTCTTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACTACCTTGCAGAGAACATCTC AACAGTGCAGTAAAATAGCTCTCCTAGACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTGTGGAATTCTGAGGAAAAAA AGCAAGATGCCTCAATGCCAATGCTGGGCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGCTCAGCTTTGGAAAATCATT TTGCCAGTAATATTGCCTGTGAATCCCTTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTTGGTGCTGAATTGAAAATGG TAAGCTAAAGCAGTGACAGATCCACGTAGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCTCAGGTTAAACCTTTGTCTT TAACCTCCCTTTGTTGTGGAGAAAATGTGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTCAGTTCCTGCAGCATAACAG ATATGACTTATGCCAGGGAAGGTAGAGGCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGGTCTGCTCCACGTAGAACCT CCCCAGATCGGAAGTTAAGTCTTGGAGAGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTTGCTTAATGAGCAAGAGGCT TGTGTCCTCCCAAGAACATGAGGGAGTTCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCACCCCATCCCTCGTGACTGGG AGCATGTTTGCTCAGAATTTTCTAAGAGGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTTAGCCTCTGAGAATCTCACT CTTTCATTTCCATCTGTGAATGGACATAGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCAGTGGCATGGTGTTGCATTA GTAGTTAGAAAAGTAATTGGTCAGCTCTACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCAGGTCTGTTCTATTGTTTTG TGATCTGAAGACTGTCAAACTGGTTGATAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGTTAGAAAGATATAGCTTACC AGTTTTCCATGTGCTTAAGGAAGTCAAGAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAGCTAGTGTCTCTCACCTTCT TAGGTGTATCAGAGAGAGGAAGTGGAAGGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCTCCATTTCAAAGACTTTGTC TTCCATCCTATCCAATGACATGGTCAGGGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTCCACTGTGGTGTGTAGTCTC CAAACAGCTTAAGGGTTTTTAAGTTTTCTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAAAGGTTAACATCCCTGGGAC CATTCTACTTATAAAAGAGATGAACTAGTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATCTCCTCTTGGCCAAGTTCAA CAAATGTTTCCAGGGAACCCCGTGGGTTGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAGGACAAAAGTATTTCTTGTC CCTTTTCCCTCATGCTCATATGTTTTAGCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGAGACAGAGAGCCAGGGACCC ATGTACCCAGGGACCAGTCCCCTGGGGAATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAACTCTGCTGCTGTTCATTTCC ATCAGGACCACCCAGGAAAGCAAATAAGTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAGGATGAGAGCATATATAGAT CTCCTGTTTAGAGAGTGTGTTCATAATTGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCATTTTTTAAGAGGATGGCAAG GATGACCTCAAATGAGCTCAACAAAACTGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTTGTGGTCCTTAAACCTCTTG GCACCTTGTGCGGGTTATAAAACAAGGAGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCAGGATTTAGGAGCTACCCAA CCTGTGGTTATATGGTGTTGGTTTCCATTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTACTGCATGGAAAGTTCAAGCT TTTCTTCTTGCCCGCTCAGGGCTGGCCTCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAGCACTCTCTGGAGCTGAGGG GAGTGAAATTTGGTCCAGAGAAGGCGGAAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCTCAGGCTTCCTTCACACCTC CTTCTCATGGGTGCGGCTGGCAGTACAGTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCAGCCCCAGGTTTGGTCTGAG ACAGGTACACAGCAGATACCATCCCACCTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCCCTACTTTACTAATGTATCC CTTATGTGGTACCAGCAATGGAGGACAGGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACCCGTAAAACTTGACCACCCC CATATCCCACTCCTTTTTGTAAAAACAAATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAATCAGTTTCCTTCCATTTGAG >6133_6133_2_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000370016_NUDT3_chr6_34309749_ENST00000607016_length(amino acids)=496AA_BP=357 MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSF RKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKAKKTYQAYHMESVNAEAKLREAERQEEKRAGRSVP TTTAGATEAGPLRKSSLKKGGRLVEKRQAKFMEHKLKCTKARNEYLLSLASVNAAVSNYYLHDVLDLMDCCDTGFHLALGQVLRSYTAAE SRTQASQVQGLGSLEEAVEALDPPGDKAKVLEVHATVFCPPLRFDYHPHDGDEVAEICVEMELRDEILPRAQNIQSRLDRQTIETEEVLL VSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIEDAI -------------------------------------------------------------- >6133_6133_3_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000370028_NUDT3_chr6_34309749_ENST00000607016_length(transcript)=10806nt_BP=1312nt GGCCCGCTCACGGCCGCGTGGGAGCAGTGGGGTTCGACGGCGCGGCCGCGAGGCCGCCATGGCCGCTCACGGGAAGCTGCGGCGGGAGCG GGGGCTGCAGGCTGAGTATGAGACGCAAGTCAAAGAGATGCGCTGGCAGCTGAGCGAGCAGCTGCGCTGCCTGGAGCTGCAGGGCGAGCT GCGGCGGGAGTTGCTGCAGGAGCTGGCAGAGTTCATGCGGCGCCGCGCTGAGGTGGAGCTGGAATACTCCCGGGGCCTGGAAAAGCTGGC CGAGCGCTTCTCCAGCCGTGGAGGCCGCCTGGGGAGCAGCCGGGAGCACCAAAGCTTCCGGAAGGAGCCGTCCCTCCTGTCGCCCTTGCA CTGCTGGGCGGTGCTGCTGCAGCACACGCGGCAGCAGAGCCGGGAGAGCGCGGCCCTGAGTGAGGTGCTGGCCGGGCCCCTGGCCCAGCG CCTGAGTCACATTGCAGAGGACGTGGGGCGCCTGGTCAAGAAGAGCAGGGATCTGGAGCAGCAGCTGCAGGATGAGCTCCTGGAGGTGGT CTCAGAGCTCCAGACGGCCAAGAAGACGTACCAGGCATATCACATGGAGAGCGTGAATGCCGAGGCCAAGCTCCGGGAGGCCGAGCGGCA GGAGGAGAAGCGGGCAGGCCGGAGTGTCCCCACCACCACCGCTGGTGCCACTGAGGCAGGGCCCCTCCGCAAGAGCTCCCTCAAGAAGGG AGGGAGGCTGGTGGAGAAGCTCTGGCCCCCGCAGAGGCCTGTGGCCGCTTCCAGCTGTGCACCTGTGTGCTGGCTCCAAGCTGGGTTTCT CGTGCACCCTCCATGGTGGGGTGCCATGTGCGCACCTTCCACTCATCAGCGGCAGGCCAAGTTCATGGAGCACAAACTCAAGTGCACAAA GGCGCGCAACGAGTACCTGCTTAGCCTGGCTAGTGTCAACGCTGCTGTCAGTAACTACTACCTGCATGACGTCTTGGACCTCATGGACTG CTGTGACACAGGGTTCCACCTGGCCCTGGGGCAGGTGCTCCGGAGCTACACGGCCGCTGAGAGCCGCACCCAAGCCTCCCAAGTGCAGGG CCTGGGCAGCCTGGAAGAAGCTGTGGAGGCCCTGGATCCTCCAGGGGACAAAGCCAAGGTTCTCGAGGTGCATGCTACCGTCTTCTGTCC CCCGCTGCGCTTTGACTACCACCCCCATGATGGGGATGAGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAG AGCCCAGAACATCCAGAGCCGCCTGGACCGACAGACCATTGAGACAGAGGAGGTGCTACTCGTGAGCAGTAGTCGCCATCCAGACAGATG GATTGTCCCTGGAGGAGGCATGGAGCCCGAGGAGGAGCCAAGTGTGGCAGCAGTTCGTGAAGTCTGTGAGGAGGCTGGAGTAAAAGGGAC ATTGGGAAGATTAGTTGGAATTTTTGAGAACCAGGAGAGGAAGCACAGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGA CTGGGAAGATTCAGTTAACATTGGAAGGAAGAGGGAATGGTTTAAAATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCA GGCATCATATTTTGAAACATTGAGGCAAGGCTACTCAGCCAACAATGGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAG CTCGATGTCAGGCATCAGATGACTGAAGACTTCCTGTAAGAGAAATGGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCC TGGCTCTTTCCACTTCTCACAGGCCTCCTCTTTCAAATAAGGCATGGTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGT GTTAAGTGATGGGGCTTTTTCTTCTGTTTTTATTGAGGGTGGGGGTTGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTC CCTCTTCCCACCCCTGCAGTCCTCTGAAGAGAGGCCAACAGCCTTCCCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGC CCTGGCCAGACGTTTTCTTTGATTTTTAATTTTTTTTTTTTATTAAAAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATA ATGTGCTGTACAGTTCAGTAGAGTGGTCACTTTCACTGCAGTATACATTTATCTACACATTATATATCGGACATATAATATGTAAATAAA TGACTTCTAGAAAGAGAAATTTGTTTAATTTTTCAAGGTTTTTTTCTCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAA CATACCTTTTTGTTTTCGATGCTAGTGGCTGGGCAGGTTGCCCTGTCCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGT TTAGCTACCTTCATAGTGCTCCCAGGACTCATGGCCTTTCCTTCTTTAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTT TTTTATTTTTTTATTTTTTTTTAACCAAGCAAGGAGCAAATGGCCTCAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCC CACATGTTGACAGTAGAGTTGGAACTGGATTCTTGGGATTACTTATCTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTG GAATCTTTTCCGTAATGCTATTTATTGCCAACAATGGCCTCTCTTTGTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCA TGTGCTCTGAAGCATCCAACTTTACTTTGCAGGTGCATCAATGTAGTCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTA GGGAAATTCACCTGCTTGCTTGTCTTTGTATTGGCATGGCACTTGTGATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCC ATCTCCCACCAGGATATGAAAGGTCCATATGGGAGGCCACGTAATCACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTC TCTTGTTTTTTGATACAGTTTCGTGCTGGCTTCATTTGCCAATTGTGTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAG GGAGGGCTACACTGACTGATCCGTGGCTTAAGACAGGAGATTATCTCTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAA TCATAGTTCGCCTCATTTAAAAATTCTAATAAAGCACTCAAACTTTGAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTAC CTCATAGCCCTGTGTCATTTAGTGTTCAGCACTTTTGGGAACATCAGTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTG GCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTG AAACCCCGTCTCTACTAAAAATGCAGAAATTAGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACC TGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGTCGTCCAGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAA AAAAATTTTTTTTTTTTTTTTTGCTATATACTCTTAGTTTACATCCTCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTC TTGGGATACCATGATACCTCTGGGAAAGGAATTATATTCCCAAGGAGAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGA ATGCCAACTTACTATTCACACATCCTTCTTAAAAACGAACACACTGTTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAA ATAAAGGGCAAAATAAAGTAGATTTAACCAAGTGCCAGGTGGAATTCAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGG ATTTGAAAGTACTTTGCAGGAAAACAGTCAGTACTCTTTAAAAAGGGACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCA CTTTGGGAGGCCAAGGCAGGTGGGTCACTTGAGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATA CAAAAATTAGCTGGGCATGATGGTGCACTCCTGTAATCCCAGCTACTTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGA GGTTGCAGTAAGCCAAGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACG GAACTGCAGTGCTAACAGTAATTTATACATTTTTAAATGTTCTGAGTATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGT GCAGTTTTGATTGTTGTTGGTGTCTTTGGGTCAGGAAAGTGAACTGTGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAAT GCAATTGACTGAGAGATTGTGCTTACGCTTTCTTAACTGACAAAAAGAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTT CTGTTGCACTGGGATTCTGATGATCTGGGATTTTCCCTCCTTGGCACAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTC CTTTAGTGATAGATTAGTTAGACCCATGGTTGCAATACCTTTATCTCCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTT TGCAGAATATTTCACTGACATTGATTTGTCATTAATTCTACCAGAGCTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGG GCAGATCCCTAGCCTCTCGCTCACAGTGAGTCTGCATGTCCTAGATTCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGG ACAGAAGAAGATAGCAGTGGATTTGTAAAAATTTTTAGTTTATAAATTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTG GACCAGGATTTTCTCTCTGTCTTCTCTCTGGGTGTGTGTGTGTGTATGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTC TGTAGTCTTCCAGAAACAGTGCAGCCCATACAACAGGAATCTTAATTTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTG TTTTCACAAGTGTCCACCACTCCATCTGCCCTGCATGGAGAGGGCTCTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAG GGTGTGGGAGTATCACCCCCTCTCAGGCTGCAGAAGGTCTCGAGGGTGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAG CCCCATGGAACATGAGGCACTTGAGGCCTTGCTTCTTGGAGCCTCTGGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTA GTTTTGTAAATGTGTTGCTACATAGTCAAGTTCCTTTGTGGCAAAGAAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTC TCAGGCTTGCTTGCTTAGAAGAAAAAAGTCACCCTTTGTGGTTTTTAAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTC CCTTTTCTCTACATACAGTGCTCATTGGAGGCTCCTGCTAAACCTTCTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACA TTTCACATGTTATCCTTCACATATTTCTCATTTTCATCTAGTACTTTCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAA AAAAAAAAAAAACAGCTTAGCCTAAGCCACATTCACTTTTTTTAGTTCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAAC TGTGTGATTTTAATATTCTCTAATATCAAGGGCGGATTTAGAATTGCAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTT AAGAGAAATGAGAGTTGGCTGTCTCTGTAATTGATAATACAGCTTCATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTAC AAAACACAGGACACTTGTGGGACAGTTAACTCAAGCAGCTATGGGGAGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTC TTCTGTTTCTTAAAGACTGTGGAAGAGGTCAGACTGCCCAGTTGAGGTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTC TGAGTCCTGTTGGATAGAGCCTATCTCCTCAAGGCTACAGAGGCTTCCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCC ATCAGGGCACCTGCCTAACTTGGAGCAAGTGGGAGAGCACCCTAGAGTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCA CCATCCGGAGGAGCTGTGTTTCTGTGTCACTTGGGATATCACCTAAAAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATT GGGGAACATTGGCTGCAGTCCCTAAAAGATACTGTTGTCTGTGCATCAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGT TTAGGCATACTCTCCTTTGGAGGCCAGCAGCCTTTCACAAACCCTGCCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAG CCTCAGAAACTCTTGTCTTTAGCTGATAACCTTTGAGGGATGTGAGAAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCA AATTAATCAAATAGTTTGTCCTTCTAGTCCCCTTATAAATTAATAAATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACT TTGGGAGGCCGAGGCGGGTGGATCACAAGGTCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAA AAATTAGCCAGGTGTAGTGGCACGCTCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGT TGCAGTGAGCCGAGATCCCGCCACTGCACTGCAGCCTAGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGG AAGGGAATCCCATTTTGTGATGATTTGGGCACACTACTTGAGCTGAGGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTT TGAAGTAAGGTTATGTCTCTTCCCTGAAGCTTTGTTTATAGTGGTAATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACT GTCCACCTGGGGAGGGGAGCTTATAGGGAACCCGTGTTAACTCAGAATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTAT CTAGAAGGTGGAAAGAAGTCATTGCTTCTGTTCCTCCAGCAGTCAGTTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATAC TAAAACTTATTTGACTTCCTATCAGGAAGCACACAAAAAAAGCGTCATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCA GCATTGTCGTTTTGCCAGGTTCATCACCATTTTGATGTGCTACCCATCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGC CAGATGTGAAGATTCTATTAATCACTGTTTCAGAGAACATTAATTCTTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACT ACCTTGCAGAGAACATCTCAACAGTGCAGTAAAATAGCTCTCCTAGACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTG TGGAATTCTGAGGAAAAAAAGCAAGATGCCTCAATGCCAATGCTGGGCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGC TCAGCTTTGGAAAATCATTTTGCCAGTAATATTGCCTGTGAATCCCTTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTT GGTGCTGAATTGAAAATGGTAAGCTAAAGCAGTGACAGATCCACGTAGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCT CAGGTTAAACCTTTGTCTTTAACCTCCCTTTGTTGTGGAGAAAATGTGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTC AGTTCCTGCAGCATAACAGATATGACTTATGCCAGGGAAGGTAGAGGCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGG TCTGCTCCACGTAGAACCTCCCCAGATCGGAAGTTAAGTCTTGGAGAGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTT GCTTAATGAGCAAGAGGCTTGTGTCCTCCCAAGAACATGAGGGAGTTCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCAC CCCATCCCTCGTGACTGGGAGCATGTTTGCTCAGAATTTTCTAAGAGGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTT AGCCTCTGAGAATCTCACTCTTTCATTTCCATCTGTGAATGGACATAGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCA GTGGCATGGTGTTGCATTAGTAGTTAGAAAAGTAATTGGTCAGCTCTACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCA GGTCTGTTCTATTGTTTTGTGATCTGAAGACTGTCAAACTGGTTGATAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGT TAGAAAGATATAGCTTACCAGTTTTCCATGTGCTTAAGGAAGTCAAGAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAG CTAGTGTCTCTCACCTTCTTAGGTGTATCAGAGAGAGGAAGTGGAAGGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCT CCATTTCAAAGACTTTGTCTTCCATCCTATCCAATGACATGGTCAGGGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTC CACTGTGGTGTGTAGTCTCCAAACAGCTTAAGGGTTTTTAAGTTTTCTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAA AGGTTAACATCCCTGGGACCATTCTACTTATAAAAGAGATGAACTAGTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATC TCCTCTTGGCCAAGTTCAACAAATGTTTCCAGGGAACCCCGTGGGTTGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAG GACAAAAGTATTTCTTGTCCCTTTTCCCTCATGCTCATATGTTTTAGCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGA GACAGAGAGCCAGGGACCCATGTACCCAGGGACCAGTCCCCTGGGGAATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAAC TCTGCTGCTGTTCATTTCCATCAGGACCACCCAGGAAAGCAAATAAGTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAG GATGAGAGCATATATAGATCTCCTGTTTAGAGAGTGTGTTCATAATTGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCAT TTTTTAAGAGGATGGCAAGGATGACCTCAAATGAGCTCAACAAAACTGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTT GTGGTCCTTAAACCTCTTGGCACCTTGTGCGGGTTATAAAACAAGGAGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCA GGATTTAGGAGCTACCCAACCTGTGGTTATATGGTGTTGGTTTCCATTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTAC TGCATGGAAAGTTCAAGCTTTTCTTCTTGCCCGCTCAGGGCTGGCCTCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAG CACTCTCTGGAGCTGAGGGGAGTGAAATTTGGTCCAGAGAAGGCGGAAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCT CAGGCTTCCTTCACACCTCCTTCTCATGGGTGCGGCTGGCAGTACAGTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCA GCCCCAGGTTTGGTCTGAGACAGGTACACAGCAGATACCATCCCACCTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCC CTACTTTACTAATGTATCCCTTATGTGGTACCAGCAATGGAGGACAGGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACC CGTAAAACTTGACCACCCCCATATCCCACTCCTTTTTGTAAAAACAAATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAAT CAGTTTCCTTCCATTTGAGCTGTGTGGGAGGGAAGGGCATTGAAATTGTAGGTTGTAATCTTGTGCCAACCAATAAAAACCAGTATTTCA >6133_6133_3_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000370028_NUDT3_chr6_34309749_ENST00000607016_length(amino acids)=557AA_BP=418 MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSF RKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTAKKTYQAYHMESVN AEAKLREAERQEEKRAGRSVPTTTAGATEAGPLRKSSLKKGGRLVEKLWPPQRPVAASSCAPVCWLQAGFLVHPPWWGAMCAPSTHQRQA KFMEHKLKCTKARNEYLLSLASVNAAVSNYYLHDVLDLMDCCDTGFHLALGQVLRSYTAAESRTQASQVQGLGSLEEAVEALDPPGDKAK VLEVHATVFCPPLRFDYHPHDGDEVAEICVEMELRDEILPRAQNIQSRLDRQTIETEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVR EVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEVLEDWEDSVNIGRKREWFKIEDAIKVLQYHKPVQASYFETLRQGYSANNGTPV -------------------------------------------------------------- >6133_6133_4_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000393721_NUDT3_chr6_34309749_ENST00000607016_length(transcript)=10146nt_BP=652nt CTCACGGCCGCGTGGGAGCAGTGGGGTTCGACGGCGCGGCCGCGAGGCCGCCATGGCCGCTCACGGGAAGCTGCGGCGGGAGCGGGGGCT GCAGGCTGAGTATGAGACGCAAGTCAAAGAGATGCGCTGGCAGCTGAGCGAGCAGCTGCGCTGCCTGGAGCTGCAGGGCGAGCTGCGGCG GGAGTTGCTGCAGGAGCTGGCAGAGTTCATGCGGCGCCGCGCTGAGGTGGAGCTGGAATACTCCCGGGGCCTGGAAAAGCTGGCCGAGCG CTTCTCCAGCCGTGGAGGCCGCCTGGGGAGCAGCCGGGAGCACCAAAGCTTCCGGAAGGAGCCGTCCCTCCTGTCGCCCTTGCACTGCTG GGCGGTGCTGCTGCAGCACACGCGGCAGCAGAGCCGGGAGAGCGCGGCCCTGAGTGAGGTGCTGGCCGGGCCCCTGGCCCAGCGCCTGAG TCACATTGCAGAGGACGTGGGGCGCCTGGTCAAGAAGAGCAGGGATCTGGAGCAGCAGCTGCAGGATGAGCTCCTGGAGGTGGTCTCAGA GCTCCAGACGGTGGCTGAGATCTGCGTTGAAATGGAGCTGCGGGACGAGATTCTGCCCAGAGCCCAGAACATCCAGAGCCGCCTGGACCG ACAGACCATTGAGACAGAGGAGGTGCTACTCGTGAGCAGTAGTCGCCATCCAGACAGATGGATTGTCCCTGGAGGAGGCATGGAGCCCGA GGAGGAGCCAAGTGTGGCAGCAGTTCGTGAAGTCTGTGAGGAGGCTGGAGTAAAAGGGACATTGGGAAGATTAGTTGGAATTTTTGAGAA CCAGGAGAGGAAGCACAGGACGTATGTCTATGTGCTCATTGTCACTGAAGTGCTGGAAGACTGGGAAGATTCAGTTAACATTGGAAGGAA GAGGGAATGGTTTAAAATAGAAGACGCCATAAAAGTGCTGCAGTATCACAAACCCGTGCAGGCATCATATTTTGAAACATTGAGGCAAGG CTACTCAGCCAACAATGGCACCCCAGTCGTGGCCACCACATACTCGGTTTCTGCTCAGAGCTCGATGTCAGGCATCAGATGACTGAAGAC TTCCTGTAAGAGAAATGGAAATTGGAAACTAGACTGAAGTGCAAATCTTCCCTCTCACCCTGGCTCTTTCCACTTCTCACAGGCCTCCTC TTTCAAATAAGGCATGGTGGGCAGCAAAGAAAGGGTGTATTGATAATGTTGCTGTTTGGTGTTAAGTGATGGGGCTTTTTCTTCTGTTTT TATTGAGGGTGGGGGTTGGGTGTGTAATTTGTAAGTACTTTTGTGCATGATCTGTCCCTCCCTCTTCCCACCCCTGCAGTCCTCTGAAGA GAGGCCAACAGCCTTCCCCTGCCTTGGATTCTGAAGTGTTCCTGTTTGTCTTATCCTGGCCCTGGCCAGACGTTTTCTTTGATTTTTAAT TTTTTTTTTTTATTAAAAGATACCAGTATGAGATGAAAACTTCCAATAATTTGTCCTATAATGTGCTGTACAGTTCAGTAGAGTGGTCAC TTTCACTGCAGTATACATTTATCTACACATTATATATCGGACATATAATATGTAAATAAATGACTTCTAGAAAGAGAAATTTGTTTAATT TTTCAAGGTTTTTTTCTCTTTTAATTTGGGCATTTCTAGAATTGAGAGCCTCACAATTAACATACCTTTTTGTTTTCGATGCTAGTGGCT GGGCAGGTTGCCCTGTCCTTTCTCTATTTCCCAGTCATTGACTGTAGATATGGGAAGAGTTTAGCTACCTTCATAGTGCTCCCAGGACTC ATGGCCTTTCCTTCTTTAAGCTGTATTTCCCTGCCCAGAAAGAAACAGGAAGAAACCTTTTTTTATTTTTTTATTTTTTTTTAACCAAGC AAGGAGCAAATGGCCTCAGCCCAGATCTGTAAAAACAATGATAGAAATTGAATTCTGCCCCACATGTTGACAGTAGAGTTGGAACTGGAT TCTTGGGATTACTTATCTAAAAAACTGGAGCATCAGGTCCATTTCTGTTCTGCTGGTTTGGAATCTTTTCCGTAATGCTATTTATTGCCA ACAATGGCCTCTCTTTGTGTCCATATATGCCTTACACCGTGCTGACCTGGGTATCATCCATGTGCTCTGAAGCATCCAACTTTACTTTGC AGGTGCATCAATGTAGTCCTGTCCCTGAACTGAGTAACCGTGTTCCTGAAAAGTACACTAGGGAAATTCACCTGCTTGCTTGTCTTTGTA TTGGCATGGCACTTGTGATTGCACCATGGAGCATGCTCAGAGCTATTAAATTGGTCTCCCATCTCCCACCAGGATATGAAAGGTCCATAT GGGAGGCCACGTAATCACTTATTACAGTGGTTACATAATACACTGGCTCACTGCAGACTCTCTTGTTTTTTGATACAGTTTCGTGCTGGC TTCATTTGCCAATTGTGTTGTTTAGTTCGGAAGTAAGAGGGTCTTGAGATTGAGGGGTAGGGAGGGCTACACTGACTGATCCGTGGCTTA AGACAGGAGATTATCTCTGTACTCCAGTGGCATCTCCTTAGCCAAGATGTGAAATTAAAATCATAGTTCGCCTCATTTAAAAATTCTAAT AAAGCACTCAAACTTTGAAAAGCTTTTACTTTTCCCTCCTACTAAAAGAAATGTATGTACCTCATAGCCCTGTGTCATTTAGTGTTCAGC ACTTTTGGGAACATCAGTTGGTGAACTTTAAATTTTGCTGTCTACTCACTGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTTGGGA GGCTGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAAAAATGCAGAAAT TAGGTGGGCGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCGAGATAATCGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGAT TGCACCACTGTCGTCCAGCCTGGGTGATAAGAGTGAAACTCCATCTCAAAAAAAAAAAAAAAAAATTTTTTTTTTTTTTTTTGCTATATA CTCTTAGTTTACATCCTCTCCCCCAATCTTCACACACAGAGCCAAAGAGCAGTTATATTCTTGGGATACCATGATACCTCTGGGAAAGGA ATTATATTCCCAAGGAGAGGTCCCATTGGATAAGAACAATACCATGGGACTTGAGTCTGAATGCCAACTTACTATTCACACATCCTTCTT AAAAACGAACACACTGTTTCTTTTCCTGACCTAGAGCATTCTAAAGTTCTGTTCAAATAAATAAAGGGCAAAATAAAGTAGATTTAACCA AGTGCCAGGTGGAATTCAAAAAACACATTCTTCCAGATAAATTCTACCTTTATGGTATGGATTTGAAAGTACTTTGCAGGAAAACAGTCA GTACTCTTTAAAAAGGGACTGCAGGGCTGGGTGTAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGGTCACTT GAGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGCAAAACCCCATCTCTACTAAAATACAAAAATTAGCTGGGCATGATGGTGCACTC CTGTAATCCCAGCTACTTGGTAGGCTGAAGCATGAGAATTGCTTAAACCTGGGAGGCAGAGGTTGCAGTAAGCCAAGATCATGCCACTGC ACTCCAGCCTGGGCAACAGAGTAAGACTCTGTCTTAATAAATAAATAAGAAAATAAAACGGAACTGCAGTGCTAACAGTAATTTATACAT TTTTAAATGTTCTGAGTATGTTTTGACTGGGCTAGTGTAACAATATACTACCCTGAAAGTGCAGTTTTGATTGTTGTTGGTGTCTTTGGG TCAGGAAAGTGAACTGTGCCAAGAAGTATTTTTCAGTGACATGAATGGATTCCTGTTAATGCAATTGACTGAGAGATTGTGCTTACGCTT TCTTAACTGACAAAAAGAGGCTTTGTCCAACATCAGAATTGTTGAAACTGGTGCTGTTTTCTGTTGCACTGGGATTCTGATGATCTGGGA TTTTCCCTCCTTGGCACAGTAAACACCATGACTGTCTTTATTGAGAATGTCGTCACAGTCCTTTAGTGATAGATTAGTTAGACCCATGGT TGCAATACCTTTATCTCCCCAAAGAAAATAATCAAAAGAAAGCACAAAAGCTACCCTGTTTGCAGAATATTTCACTGACATTGATTTGTC ATTAATTCTACCAGAGCTGACCTCATTCAGGCTTGATAGAAACAGGTTCCTATGTTTAGGGCAGATCCCTAGCCTCTCGCTCACAGTGAG TCTGCATGTCCTAGATTCTGGTTATTGCTGGAGCATCCATTAAAGTCTACCAAACTCAGGACAGAAGAAGATAGCAGTGGATTTGTAAAA ATTTTTAGTTTATAAATTACAGTCATTGGGGAAACACTAGTAAGGTCATGTGATCTTTTGGACCAGGATTTTCTCTCTGTCTTCTCTCTG GGTGTGTGTGTGTGTATGTACAGAAGGGCTACCAGGAAGTGTCAACCATGTTAGATTTTCTGTAGTCTTCCAGAAACAGTGCAGCCCATA CAACAGGAATCTTAATTTTCCTCACAGCAAATATAACAGGATGGAACAGTTAGTGTTTTGTTTTCACAAGTGTCCACCACTCCATCTGCC CTGCATGGAGAGGGCTCTCTCACTGCTAGATCTAGGCTGAGCCATCTGGAAGGATCAAAGGGTGTGGGAGTATCACCCCCTCTCAGGCTG CAGAAGGTCTCGAGGGTGGCGTCACAGCAGGATTTCCGCCTTCTGCATTGCACTGCACAGCCCCATGGAACATGAGGCACTTGAGGCCTT GCTTCTTGGAGCCTCTGGGGAGCAGAGTAGGTCACTGCCCTCTGGGAGTGTTTTGCAGTAGTTTTGTAAATGTGTTGCTACATAGTCAAG TTCCTTTGTGGCAAAGAAATATTTTGTTTTGATATTAGGAGCCAGCCCATGTAATGCCTCTCAGGCTTGCTTGCTTAGAAGAAAAAAGTC ACCCTTTGTGGTTTTTAAGAAAAAAATTCTGTGCAGATCTGTTCCTCCTCCTGCTCCTTCCCTTTTCTCTACATACAGTGCTCATTGGAG GCTCCTGCTAAACCTTCTTAACCAGAGAAATAATAGGTATTTGTTAGACCTGAGTGTACATTTCACATGTTATCCTTCACATATTTCTCA TTTTCATCTAGTACTTTCTTAATGCCTTTGTTGGAGTCCGCATCCTCATCTTTAAAAAAAAAAAAAAAAAAACAGCTTAGCCTAAGCCAC ATTCACTTTTTTTAGTTCACAAAAAGGATTTAATAGCCACAATGTGATTTTTGCCACAACTGTGTGATTTTAATATTCTCTAATATCAAG GGCGGATTTAGAATTGCAGGAAATACCTGGAGAAATCACAGTGGAATGAATTTTTGCTTTAAGAGAAATGAGAGTTGGCTGTCTCTGTAA TTGATAATACAGCTTCATCCTAGTCCCATCTGCATTTCAGAAAATAACCCTCATCTTTACAAAACACAGGACACTTGTGGGACAGTTAAC TCAAGCAGCTATGGGGAGGGAGGAGATTATTGAATGGTGATTAAATAATGCAAATGGCTCTTCTGTTTCTTAAAGACTGTGGAAGAGGTC AGACTGCCCAGTTGAGGTGGGCAGTTCATACTGCTCAGTTGAGGTGGCAGTCATTTATTCTGAGTCCTGTTGGATAGAGCCTATCTCCTC AAGGCTACAGAGGCTTCCAGGATATGGAGCTGTGCATGTTAATGGCTCAGCCTTGCCTCCATCAGGGCACCTGCCTAACTTGGAGCAAGT GGGAGAGCACCCTAGAGTCATCCTCTGTGCTGTTTCGTGAGTTTTGCAGCGGAGACTTCACCATCCGGAGGAGCTGTGTTTCTGTGTCAC TTGGGATATCACCTAAAAATGAAACATTTGATATTTTAAGGTATAAAAAAAAAGTAAATTGGGGAACATTGGCTGCAGTCCCTAAAAGAT ACTGTTGTCTGTGCATCAGGTTAGCTTGAGGTCACCACAGGTCCTGGGAGCCCAGAGAGTTTAGGCATACTCTCCTTTGGAGGCCAGCAG CCTTTCACAAACCCTGCCTCTAAAAGGGCGGTTTCACATTTGACCATGTTTTTGCATTAGCCTCAGAAACTCTTGTCTTTAGCTGATAAC CTTTGAGGGATGTGAGAAGCCTAGTTGGAGCATCTGAGAAAATGATACCTCTCACCTTCAAATTAATCAAATAGTTTGTCCTTCTAGTCC CCTTATAAATTAATAAATGGAGGGCTGGTCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACAAGG TCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTAGTGGCACGCTCCTG TAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGGATGTTGCAGTGAGCCGAGATCCCGCCACTGCACT GCAGCCTAGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGGGAAGGGAATCCCATTTTGTGATGATTTGGGC ACACTACTTGAGCTGAGGCTAGCAGTCACATGATTTTGGCTGTCTCTGACCTGAAGCTTTTGAAGTAAGGTTATGTCTCTTCCCTGAAGC TTTGTTTATAGTGGTAATTTGGTGAGTTTGAGCTTTGAGCTTGTCTTAGAAAATAAGACTGTCCACCTGGGGAGGGGAGCTTATAGGGAA CCCGTGTTAACTCAGAATGCTGAAGAAAGTGCTTTTAGCCAACAAAAGTAAGATTACTATCTAGAAGGTGGAAAGAAGTCATTGCTTCTG TTCCTCCAGCAGTCAGTTGACTCTAGGTTTCCTTTGGTTTATATCCCCAGTTCTTAATACTAAAACTTATTTGACTTCCTATCAGGAAGC ACACAAAAAAAGCGTCATTTAAAACCCTGGATATAGGCTTTAAAGGATACAAAAACAGCAGCATTGTCGTTTTGCCAGGTTCATCACCAT TTTGATGTGCTACCCATCCTTCCACCCTCCCTTTCCTGCCCCCAAGCCTCCCAGCCAGGCCAGATGTGAAGATTCTATTAATCACTGTTT CAGAGAACATTAATTCTTGTATAGAATAATTATCTACTAAATTGCTTATTATCTGTGACTACCTTGCAGAGAACATCTCAACAGTGCAGT AAAATAGCTCTCCTAGACTTGAGCTTCCAGCCAGGCATTTAGATCACTCTTAAGCCTTTGTGGAATTCTGAGGAAAAAAAGCAAGATGCC TCAATGCCAATGCTGGGCCATAAGATTCTACTCCCCTCCCTGTAGGGTGGGGCGCGTGGCTCAGCTTTGGAAAATCATTTTGCCAGTAAT ATTGCCTGTGAATCCCTTTAAGAAGTCGTCCTGATCTGAGCCTGTCTTTCTGAGCACTTTGGTGCTGAATTGAAAATGGTAAGCTAAAGC AGTGACAGATCCACGTAGCCTCTTTAACCTCTTTATTATCTTGCCAAAAAAAAAGTTTCTCAGGTTAAACCTTTGTCTTTAACCTCCCTT TGTTGTGGAGAAAATGTGTCACTAATCAGTGGTCCAAGGGATATCTAGCTTTGGTTACTCAGTTCCTGCAGCATAACAGATATGACTTAT GCCAGGGAAGGTAGAGGCTGATTATGGAGACACCCAGGAACAGGAATAAGAAGGGATAGGTCTGCTCCACGTAGAACCTCCCCAGATCGG AAGTTAAGTCTTGGAGAGTTTCCAAAGTGCTGAAGTAAAAAGGAGACTTGGAGGGCCTTTGCTTAATGAGCAAGAGGCTTGTGTCCTCCC AAGAACATGAGGGAGTTCAGAAGGGAGCTATAGCTCACAGACAGAAACCTGCCCGCTCACCCCATCCCTCGTGACTGGGAGCATGTTTGC TCAGAATTTTCTAAGAGGACTCTCCCTTCAAAAATCCAATTTGCTCCCAGAATGTTGTTTAGCCTCTGAGAATCTCACTCTTTCATTTCC ATCTGTGAATGGACATAGATGTGTTGCTCAGGGATCAGAAACATCAGAGTCCAGGGCCCAGTGGCATGGTGTTGCATTAGTAGTTAGAAA AGTAATTGGTCAGCTCTACTGTAAAAGAAATAAGTATGTAGTACAGTTTTGTAAATGTCAGGTCTGTTCTATTGTTTTGTGATCTGAAGA CTGTCAAACTGGTTGATAATCAAAGAAAAGGTTGGTGGTTAGAATAAGTAAAATTTCAGTTAGAAAGATATAGCTTACCAGTTTTCCATG TGCTTAAGGAAGTCAAGAATATTTCAGGTTGTTGAGAACTGTTGTAAAATGGAATTGAAGCTAGTGTCTCTCACCTTCTTAGGTGTATCA GAGAGAGGAAGTGGAAGGCCAGTAGTAGCATCTTCATACTTACTTTTGCCAGCCCAGCCTCCATTTCAAAGACTTTGTCTTCCATCCTAT CCAATGACATGGTCAGGGATGGGCTCTGAGGAGGCAGTGAGGCCCCACCTTGGTTTGCTCCACTGTGGTGTGTAGTCTCCAAACAGCTTA AGGGTTTTTAAGTTTTCTCACGATTACCTCCACTCCACTCATCTACTATCAGCATCAGAAAGGTTAACATCCCTGGGACCATTCTACTTA TAAAAGAGATGAACTAGTGTGCTTTCTCCCCTTTTCCAGGTGTGCCATCCATATACAATCTCCTCTTGGCCAAGTTCAACAAATGTTTCC AGGGAACCCCGTGGGTTGAGGCAAAGTAGCCAAGATGTATTGAGTTAAGTTTTTCTAGAGGACAAAAGTATTTCTTGTCCCTTTTCCCTC ATGCTCATATGTTTTAGCTGAGGCGTAAATGGCCAAGTTGAGTAATATCTGTGGAACTGAGACAGAGAGCCAGGGACCCATGTACCCAGG GACCAGTCCCCTGGGGAATCACACAGTGGCTCAGACTAGACTGCTCTATCCCACCAGAACTCTGCTGCTGTTCATTTCCATCAGGACCAC CCAGGAAAGCAAATAAGTTAGCCTTCTCATCATTAGGTCACCTAATCTCTTGGGTTGCAGGATGAGAGCATATATAGATCTCCTGTTTAG AGAGTGTGTTCATAATTGTAGAAAGGGATAGAAAATGGAATAACCAAGAGGCTGTGTCATTTTTTAAGAGGATGGCAAGGATGACCTCAA ATGAGCTCAACAAAACTGGGAATCCAAGGAATGGTGCTTGTAGGGAAAGAGAGGTCAGTTGTGGTCCTTAAACCTCTTGGCACCTTGTGC GGGTTATAAAACAAGGAGCTGGAGTAAAATTGCCCTTACCCCCAATCCAAATGCTGTCCAGGATTTAGGAGCTACCCAACCTGTGGTTAT ATGGTGTTGGTTTCCATTTTTTGTTTGTTTGCTTGTTTCCAAAATAGCCTTGCTTGGTACTGCATGGAAAGTTCAAGCTTTTCTTCTTGC CCGCTCAGGGCTGGCCTCTTCCCCGTGTCTTCACAGCGTCCCTAAGGAAGATTTTTGCAGCACTCTCTGGAGCTGAGGGGAGTGAAATTT GGTCCAGAGAAGGCGGAAGGAAATAGTTTTCCTGTTTCCTTTTCTCGAGGTGGATGTCCTCAGGCTTCCTTCACACCTCCTTCTCATGGG TGCGGCTGGCAGTACAGTCAGGCTGTGGAGGAGGGCTGAGAAGAAAGGGGCACTGGTCCAGCCCCAGGTTTGGTCTGAGACAGGTACACA GCAGATACCATCCCACCTTCCTCTCTAAAGAACAGGCCAGCCACACATATAACCCTTTCCCTACTTTACTAATGTATCCCTTATGTGGTA CCAGCAATGGAGGACAGGCAGACTTACCCCCTGCCATCTAGAGAGAATGTTGTTATTACCCGTAAAACTTGACCACCCCCATATCCCACT CCTTTTTGTAAAAACAAATGCTTAAACCTGTGAGCCTGCCGTTCCTTTCTATGTGTTAATCAGTTTCCTTCCATTTGAGCTGTGTGGGAG >6133_6133_4_ARHGAP4-NUDT3_ARHGAP4_chrX_153179232_ENST00000393721_NUDT3_chr6_34309749_ENST00000607016_length(amino acids)=339AA_BP=200 MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSF RKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTVAEICVEMELRDEI LPRAQNIQSRLDRQTIETEEVLLVSSSRHPDRWIVPGGGMEPEEEPSVAAVREVCEEAGVKGTLGRLVGIFENQERKHRTYVYVLIVTEV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ARHGAP4-NUDT3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ARHGAP4-NUDT3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ARHGAP4-NUDT3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ARHGAP4 | C0019693 | HIV Infections | 1 | CTD_human |
| Hgene | ARHGAP4 | C4505456 | HIV Coinfection | 1 | CTD_human |
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