|
||||||
|
Fusion gene:RSF1_ADAM2 (FusionGDB2 ID:HG51773TG2515) |
Fusion Gene Summary for RSF1_ADAM2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RSF1_ADAM2 | Fusion gene ID: hg51773tg2515 | Hgene | Tgene | Gene symbol | RSF1 | ADAM2 | Gene ID | 51773 | 2515 |
| Gene name | remodeling and spacing factor 1 | ADAM metallopeptidase domain 2 | |
| Synonyms | HBXAP|RSF-1|XAP8|p325 | CRYN1|CRYN2|CT15|FTNB|PH-30b|PH30|PH30-beta | |
| Cytomap | 11q14.1 | 8p11.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | remodeling and spacing factor 1HBV pX-associated protein 8hepatitis B virus x-associated proteinp325 subunit of RSF chromatin-remodeling complex | disintegrin and metalloproteinase domain-containing protein 2cancer/testis antigen 15fertilin subunit beta | |
| Modification date | 20240407 | 20240305 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000308488, ENST00000360355, ENST00000480887, ENST00000530604, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 29 X 34 X 20=19720 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 5 X 15 X 5=375 |
| # samples | 173 | 21 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(173/19720*10)=-3.51081560874119 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(21/375*10)=-0.836501267717121 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RSF1 [Title/Abstract] AND ADAM2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RSF1(77458080)-ADAM2(39607263), # samples:1 | ||
| Fusion gene breakpoints across RSF1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across ADAM2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Fusion Gene Breakpoints for RSF1_ADAM2 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 |
| RSF1 | chr11 | 77458081 | ADAM2 | chr8 | 39607263 |
| RSF1 | chr11 | 77747036 | ADAM2 | chr8 | 39749744 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
Top |
Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for RSF1_ADAM2 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| RSF1-ADAM2 | Epigenetic Reprogramming / Histone Modifier Dysregulation M3 | RSF1 chromatin remodeler couples to ADAM2 metalloproteinase, coordinating chromatin remodeling with cell-surface proteolytic ectodomain shedding. | Metalloproteinase inhibitors; HDAC inhibitors | Desmoplastic and invasive solid tumors |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| RSF1-ADAM2 | Epigenetic Reprogramming / Histone Modifier Dysregulation M3 | RSF1 chromatin remodeler couples to ADAM2 metalloproteinase, coordinating chromatin remodeling with cell-surface proteolytic ectodomain shedding. | Metalloproteinase inhibitors; HDAC inhibitors | Desmoplastic and invasive solid tumors | Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 27363013; Title: Comprehensive analysis of differentially expressed profiles of lncRNAs and circRNAs with associated co-expression and ceRNA networks in bladder carcinoma.; PMID: 19893039; Title: Novel biomarkers for prostate cancer including noncoding transcripts. |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RSF1 | GO:0006325 | chromatin organization | 11691835 |
| Hgene | RSF1 | GO:0006334 | nucleosome assembly | 12972596 |
| Hgene | RSF1 | GO:0006338 | chromatin remodeling | 9836642 |
| Hgene | RSF1 | GO:0006352 | DNA-templated transcription initiation | 9836642 |
| Hgene | RSF1 | GO:0006355 | regulation of DNA-templated transcription | 12972596 |
| Hgene | RSF1 | GO:0043392 | negative regulation of DNA binding | 12972596 |
| Hgene | RSF1 | GO:0045892 | negative regulation of DNA-templated transcription | 11944984 |
| Hgene | RSF1 | GO:0045893 | positive regulation of DNA-templated transcription | 11788598 |
| Hgene | RSF1 | GO:0050434 | positive regulation of viral transcription | 11788598 |
Top |
Fusion Genomic Features for RSF1_ADAM2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - | 2.14e-03 | 9.98e-01 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
 |
Top |
Fusion Gene ORF Annotations for RSF1_ADAM2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000308488 | ENST00000265708 | RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - |
| In-frame | ENST00000308488 | ENST00000347580 | RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - |
| In-frame | ENST00000308488 | ENST00000379853 | RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - |
| In-frame | ENST00000308488 | ENST00000521880 | RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000308488 | ENST00000265708 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 675 | 260 |
| ENST00000308488 | ENST00000347580 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 675 | 327 |
| ENST00000308488 | ENST00000379853 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 675 | 260 |
| ENST00000308488 | ENST00000521880 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 675 | 260 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000308488 | ENST00000265708 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 3.89e-03 | 9.96e-01 |
| ENST00000308488 | ENST00000347580 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 3.89e-03 | 9.96e-01 |
| ENST00000308488 | ENST00000379853 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 3.89e-03 | 9.96e-01 |
| ENST00000308488 | ENST00000521880 | RSF1 | chr11 | 77458080 | ADAM2 | chr8 | 39607263 | 1.77e-03 | 9.98e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
Top |
Fusion Protein Retained/Non-Retained Functional Features for RSF1_ADAM2 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
 |
| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
RSF1_ADAM2_chr11-77458080_chr8-39607263.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 17_84 | 124.0 | 1442.0 | Domain | Note=DDT |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 612_645 | 599.0 | 788.6666666666666 | Domain | Note=EGF-like |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 708_735 | 599.0 | 788.6666666666666 | Topological domain | Cytoplasmic |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 687_707 | 599.0 | 788.6666666666666 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 942_1012 | 124.0 | 1442.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1094_1107 | 124.0 | 1442.0 | Compositional bias | Acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1120_1141 | 124.0 | 1442.0 | Compositional bias | Acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1146_1169 | 124.0 | 1442.0 | Compositional bias | Basic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1189_1199 | 124.0 | 1442.0 | Compositional bias | Acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1203_1212 | 124.0 | 1442.0 | Compositional bias | Basic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1229_1244 | 124.0 | 1442.0 | Compositional bias | Basic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1280_1292 | 124.0 | 1442.0 | Compositional bias | Acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1335_1344 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1394_1408 | 124.0 | 1442.0 | Compositional bias | Polar residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 215_227 | 124.0 | 1442.0 | Compositional bias | Polar residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 234_257 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 274_283 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 330_340 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 359_378 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 467_480 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 482_498 | 124.0 | 1442.0 | Compositional bias | Polar residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 500_514 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 552_562 | 124.0 | 1442.0 | Compositional bias | Polar residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 565_601 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 609_621 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 753_770 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 789_802 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 816_831 | 124.0 | 1442.0 | Compositional bias | Basic and acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 864_873 | 124.0 | 1442.0 | Compositional bias | Low complexity |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 874_887 | 124.0 | 1442.0 | Compositional bias | Acidic residues |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 1063_1428 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 215_283 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 330_385 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 467_634 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 675_887 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 983_1007 | 124.0 | 1442.0 | Region | Disordered |
| Hgene | RSF1 | chr11:77458080 | chr8:39607263 | ENST00000308488 | Q96T23 | 3 | 16 | 891_941 | 124.0 | 1442.0 | Zinc finger | PHD-type |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 178_375 | 599.0 | 788.6666666666666 | Domain | Peptidase M12B |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 384_473 | 599.0 | 788.6666666666666 | Domain | Disintegrin |
| Tgene | ADAM2 | chr11:77458080 | chr8:39607263 | ENST00000265708 | Q99965 | 15 | 21 | 175_686 | 599.0 | 788.6666666666666 | Topological domain | Extracellular |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Fusion Transcript Sequence for RSF1_ADAM2 |
| In-frame Fusion Transcript Sequences. |
>RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263 length=1446nt Breakpoint=675nt TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGCCGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTAT TGTGGGATCGCGGAGCCGTCCCTGAGACGCTGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCCATCGCCTCCTCCTCCATCCTCCAGTTC AAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGATATGCCAAGAGTTTAAC AGTACCTGGGCATGGGAGATGGAGAAGAAGGGCTATCTTGAAATGAGTGTTGAATGCAAACTAGCACTCTTAAAGGTTTGCAGGAATCAAAGATGTGTGAGTTCTTCATACTTGGGTTATGATTGTACTACTGACAAATGCAATGATAGA GGTGTATGCAATAACAAAAAGCACTGTCACTGTAGTGCTTCATATTTACCTCCAGATTGCTCAGTTCAATCAGATCTATGGCCTGGTGGGAGTATTGACAGTGGCAATTTTCCACCTGTAGCTATACCAGCCAGACTCCCTGAAAGGCGC TACATTGAGAACATTTACCATTCCAAACCAATGAGATGGCCATTTTTCTTATTCATTCCTTTCTTTATTATTTTCTGTGTACTGATTGCTATAATGGTGAAAGTTAATTTCCAAAGGAAAAAATGGAGAACTGAGGACTATTCAAGCGAT GAGCAACCTGAAAGTGAGAGTGAACCTAAAGGGTAGTCTGGACAACAGAGATGCCATGATATCACTTCTTCTAGAGTAATTATCTGTGATGGATGGACACAAAAAAATGGAAAGAAAAGAATGTACATTACCTGGTTTCCTGGGATTCAA ACCTGCATATTGTGATTTTAATTTGACCAGAAAATATGATATATATGTATAATTTCACAGATAATTTACTTATTTAAAAATGCATGATAATGAGTTTTACATTACAAATTTCTGTTTTTTTAAAGTTATCTTACGCTATTTCTGTTGGTT AGTAGACACTAATTCTGTCAGTAGGGGCATGGTATAAGGAAATATCATAATGTAATGAGGTGGTACTATGATTAAAAGCCACTGTTACATTTCAAA >RSF1_ADAM2_ENST00000308488_ENST00000347580_77458080_39607263 length=1446nt Breakpoint=675nt TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGCCGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTAT TGTGGGATCGCGGAGCCGTCCCTGAGACGCTGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCCATCGCCTCCTCCTCCATCCTCCAGTTC AAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGATATGCCAAGAGTTTAAC AGTACCTGGGCATGGGAGATGGAGAAGAAGGGCTATCTTGAAATGAGTGTTGAATGCAAACTAGCACTCTTAAAGGTTTGCAGGAATCAAAGATGTGTGAGTTCTTCATACTTGGGTTATGATTGTACTACTGACAAATGCAATGATAGA GGTGTATGCAATAACAAAAAGCACTGTCACTGTAGTGCTTCATATTTACCTCCAGATTGCTCAGTTCAATCAGATCTATGGCCTGGTGGGAGTATTGACAGTGGCAATTTTCCACCTGTAGCTATACCAGCCAGACTCCCTGAAAGGCGC TACATTGAGAACATTTACCATTCCAAACCAATGAGATGGCCATTTTTCTTATTCATTCCTTTCTTTATTATTTTCTGTGTACTGATTGCTATAATGGTGAAAGTTAATTTCCAAAGGAAAAAATGGAGAACTGAGGACTATTCAAGCGAT GAGCAACCTGAAAGTGAGAGTGAACCTAAAGGGTAGTCTGGACAACAGAGATGCCATGATATCACTTCTTCTAGAGTAATTATCTGTGATGGATGGACACAAAAAAATGGAAAGAAAAGAATGTACATTACCTGGTTTCCTGGGATTCAA ACCTGCATATTGTGATTTTAATTTGACCAGAAAATATGATATATATGTATAATTTCACAGATAATTTACTTATTTAAAAATGCATGATAATGAGTTTTACATTACAAATTTCTGTTTTTTTAAAGTTATCTTACGCTATTTCTGTTGGTT AGTAGACACTAATTCTGTCAGTAGGGGCATGGTATAAGGAAATATCATAATGTAATGAGGTGGTACTATGATTAAAAGCCACTGTTACATTTCAAA >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263 length=1446nt Breakpoint=675nt TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGCCGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTAT TGTGGGATCGCGGAGCCGTCCCTGAGACGCTGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCCATCGCCTCCTCCTCCATCCTCCAGTTC AAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGATATGCCAAGAGTTTAAC AGTACCTGGGCATGGGAGATGGAGAAGAAGGGCTATCTTGAAATGAGTGTTGAATGCAAACTAGCACTCTTAAAGGTTTGCAGGAATCAAAGATGTGTGAGTTCTTCATACTTGGGTTATGATTGTACTACTGACAAATGCAATGATAGA GGTGTATGCAATAACAAAAAGCACTGTCACTGTAGTGCTTCATATTTACCTCCAGATTGCTCAGTTCAATCAGATCTATGGCCTGGTGGGAGTATTGACAGTGGCAATTTTCCACCTGTAGCTATACCAGCCAGACTCCCTGAAAGGCGC TACATTGAGAACATTTACCATTCCAAACCAATGAGATGGCCATTTTTCTTATTCATTCCTTTCTTTATTATTTTCTGTGTACTGATTGCTATAATGGTGAAAGTTAATTTCCAAAGGAAAAAATGGAGAACTGAGGACTATTCAAGCGAT GAGCAACCTGAAAGTGAGAGTGAACCTAAAGGGTAGTCTGGACAACAGAGATGCCATGATATCACTTCTTCTAGAGTAATTATCTGTGATGGATGGACACAAAAAAATGGAAAGAAAAGAATGTACATTACCTGGTTTCCTGGGATTCAA ACCTGCATATTGTGATTTTAATTTGACCAGAAAATATGATATATATGTATAATTTCACAGATAATTTACTTATTTAAAAATGCATGATAATGAGTTTTACATTACAAATTTCTGTTTTTTTAAAGTTATCTTACGCTATTTCTGTTGGTT AGTAGACACTAATTCTGTCAGTAGGGGCATGGTATAAGGAAATATCATAATGTAATGAGGTGGTACTATGATTAAAAGCCACTGTTACATTTCAAA >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263 length=1150nt Breakpoint=675nt TTGTTTTCATTCCCCCTGTCACACGAGGCAGTGGCAAGCCCGAAGGGGAGGAGAGAAGGGGGCGGAAAGAGGGCGGAAAGTGAAAGGCGCCGAGGGCCGCTCTGTCTCCCGTCTGACTCGGTTCTCGACTGCTCCGGGCCGCCGATGTAT TGTGGGATCGCGGAGCCGTCCCTGAGACGCTGGGATCCGCAGAGGAGCCCACTTGAGAGCGCCTCCTGTCGTCTGTAAGGTTGCCTTGCCATCCCTCGGCACCACAACTTCCCCCGCCCCCCCATCGCCTCCTCCTCCATCCTCCAGTTC AAAATGGCGACGGCGGCGGCAGCGGCGGCGGTGATGGCTCCTCCGGGCTGCCCGGGTTCGTGCCCCAACTTCGCCGTAGTCTGCTCCTTCTTGGAGCGCTACGGGCCGCTGCTAGACCTGCCTGAGTTGCCGTTCCCTGAGCTGGAGCGG GTGCTGCAGGCGCCGCCGCCGGACGTCGGCAACGGAGAAGTACCAAAAGAATTGGTGGAGCTCCATTTGAAGCTGATGAGGAAAATTGGCAAATCTGTTACTGCAGACAGATGGGAAAAATATTTGATCAAGATATGCCAAGAGTTTAAC AGTACCTGGGCATGGGAGATGGAGAAGAAGGGCTATCTTGAAATGAGTGTTGAATGCAAACTAGCACTCTTAAAGGTTTGCAGGAATCAAAGATGTGTGAGTTCTTCATACTTGGGTTATGATTGTACTACTGACAAATGCAATGATAGA GGTGTATGCAATAACAAAAAGCACTGTCACTGTAGTGCTTCATATTTACCTCCAGATTGCTCAGTTCAATCAGATCTATGGCCTGGTGGGAGTATTGACAGTGGCAATTTTCCACCTGTAGCTATACCAGCCAGACTCCCTGAAAGGCGC TACATTGAGAACATTTACCATTCCAAACCAATGAGATGGCCATTTTTCTTATTCATTCCTTTCTTTATTATTTTCTGTGTACTGATTGCTATAATGGTGAAAGTTAATTTCCAAAGGAAAAAATGGAGAACTGAGGACTATTCAAGCGAT GAGCAACCTGAAAGTGAGAGTGAACCTAAAGGGTAGTCTGGACAACAGAGATGCCATGATATCACTTCTTCTAGAGTAATTATCTGTGATGGATGGACAC |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
Top |
Fusion Protein Sequence for RSF1_ADAM2 |
| In-frame Fusion Protein Sequences. |
>RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263 length=260nt MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000347580_77458080_39607263 length=327nt MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQD DQDGSSWKCIVRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVE QLIKKHEEEEAKAEREKKEKEQKEKDK >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263 length=260nt MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263 length=260nt MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
Top |
Personalized Fusion Protein Sequence for RSF1_ADAM2 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.I656T_260_I181T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSTDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.C635F_260_C160F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHFSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.G625C_260_G150C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRC VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.P688L_260_P213L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWLFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.C616F_260_C141F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDFTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.P733A_260_P258A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEAKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.K630Q_260_K155Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNQKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.C621Y_260_C146Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKYNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.G18D_260_G18D length=260AA MATAAAAAAVMAPPGCPDSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.A7V_260_A7V length=260AA MATAAAVAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.V626A_260_V151A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG ACNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.L112I_260_L112I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYIEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.N603D_260_N128D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRDQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.S115G_260_S115G length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMGVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.F695L_260_F220L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPLFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.L640V_260_L165V length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYVPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.F690Y_260_F215Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFYLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.D623Y_260_D148Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNYRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R605I_260_R130I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQICVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.P667L_260_P192L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAILARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R605K_260_R130K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQKCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.Q604E_260_Q129E length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNERCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.S682F_260_S207F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHFKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.D619N_260_D144N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTNKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.A665T_260_A190T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVTIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.G659D_260_G184D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSDNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.E88K_260_E88K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWKKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.N603T_260_N128T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRTQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.L72F_260_L72F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHFKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.T3A_260_T3A length=260AA MAAAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.P667S_260_P192S length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAISARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_5-gene_p.E97Q_260_E97Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQQFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000265708_77458080_39607263_3-gene_p.R713K_260_R238K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQKKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.I656T_260_I181T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSTDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.C635F_260_C160F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHFSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.G625C_260_G150C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRC VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.P688L_260_P213L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWLFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.C616F_260_C141F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDFTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.P733A_260_P258A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEAKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.K630Q_260_K155Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNQKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.C621Y_260_C146Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKYNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.G18D_260_G18D length=260AA MATAAAAAAVMAPPGCPDSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.A7V_260_A7V length=260AA MATAAAVAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.V626A_260_V151A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG ACNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.L112I_260_L112I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYIEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.N603D_260_N128D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRDQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.S115G_260_S115G length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMGVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.F695L_260_F220L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPLFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.L640V_260_L165V length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYVPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.F690Y_260_F215Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFYLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.D623Y_260_D148Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNYRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R605I_260_R130I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQICVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.P667L_260_P192L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAILARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R605K_260_R130K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQKCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.Q604E_260_Q129E length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNERCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.S682F_260_S207F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHFKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.D619N_260_D144N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTNKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.A665T_260_A190T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVTIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.G659D_260_G184D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSDNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.E88K_260_E88K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWKKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.N603T_260_N128T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRTQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.L72F_260_L72F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHFKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.T3A_260_T3A length=260AA MAAAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.P667S_260_P192S length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAISARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_5-gene_p.E97Q_260_E97Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQQFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000379853_77458080_39607263_3-gene_p.R713K_260_R238K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQKKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.I656T_260_I181T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSTDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.C635F_260_C160F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHFSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.G625C_260_G150C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRC VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.P688L_260_P213L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWLFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.C616F_260_C141F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDFTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.P733A_260_P258A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEAKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.K630Q_260_K155Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNQKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.C621Y_260_C146Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKYNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.G18D_260_G18D length=260AA MATAAAAAAVMAPPGCPDSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.A7V_260_A7V length=260AA MATAAAVAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.V626A_260_V151A length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG ACNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.L112I_260_L112I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYIEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.N603D_260_N128D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRDQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.S115G_260_S115G length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMGVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.F695L_260_F220L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPLFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.L640V_260_L165V length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYVPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.F690Y_260_F215Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFYLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R674H_260_R199H length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERHYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.D623Y_260_D148Y length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNYRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R605I_260_R130I length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQICVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.P667L_260_P192L length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAILARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R605K_260_R130K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQKCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.Q604E_260_Q129E length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNERCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.S682F_260_S207F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHFKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.D619N_260_D144N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTNKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.A665T_260_A190T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVTIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.G659D_260_G184D length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSDNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.E88K_260_E88K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWKKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.N603T_260_N128T length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRTQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.L72F_260_L72F length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHFKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R674C_260_R199C length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERCYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.T3A_260_T3A length=260AA MAAAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.P667S_260_P192S length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAISARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_5-gene_p.E97Q_260_E97Q length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQQFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSDEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.D724N_260_D249N length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQRKKWRTEDYSSNEQPESESEPKG >RSF1_ADAM2_ENST00000308488_ENST00000521880_77458080_39607263_3-gene_p.R713K_260_R238K length=260AA MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKVCRNQRCVSSSYLGYDCTTDKCNDRG VCNNKKHCHCSASYLPPDCSVQSDLWPGGSIDSGNFPPVAIPARLPERRYIENIYHSKPMRWPFFLFIPFFIIFCVLIAIMVKVNFQKKKWRTEDYSSDEQPESESEPKG |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-13-2071-01A | 3-gene | p.I656T | 260 | I181T |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-29-1774-01A | 3-gene | p.C635F | 260 | C160F |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-2W-A8YY-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-37-3792-01A | 3-gene | p.G625C | 260 | G150C |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-38-4629-01A | 3-gene | p.P688L | 260 | P213L |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-38-4631-01A | 3-gene | p.C616F | 260 | C141F |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-63-5131-01A | 3-gene | p.P733A | 260 | P258A |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-68-7755-01A | 3-gene | p.K630Q | 260 | K155Q |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AA-A024-01A | 3-gene | p.C621Y | 260 | C146Y |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AB-2883-03A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AD-5900-01A | 5-gene | p.G18D | 260 | G18D |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AF-A56K-01A | 5-gene | p.A7V | 260 | A7V |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AJ-A3EL-01A | 3-gene | p.V626A | 260 | V151A |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AN-A046-01A | 5-gene | p.L112I | 260 | L112I |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AP-A051-01A | 3-gene | p.N603D | 260 | N128D |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AP-A1DK-01A | 5-gene | p.S115G | 260 | S115G |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AX-A0J0-01A | 3-gene | p.F695L | 260 | F220L |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-AY-4070-01A | 3-gene | p.L640V | 260 | L165V |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-BF-AAP0-06A | 3-gene | p.F690Y | 260 | F215Y |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-BQ-5892-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-BS-A0UV-01A | 3-gene | p.D623Y | 260 | D148Y |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-CA-6717-01A | 3-gene | p.R605I | 260 | R130I |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-CW-5587-01A | 3-gene | p.P667L | 260 | P192L |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-DA-A960-01A | 3-gene | p.R605K | 260 | R130K |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-DK-A1AD-01A | 3-gene | p.Q604E | 260 | Q129E |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-DK-A6AW-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EB-A85J-01A | 3-gene | p.S682F | 260 | S207F |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EE-A29D-06A | 3-gene | p.D619N | 260 | D144N |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EE-A2GH-06A | 3-gene | p.A665T | 260 | A190T |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EI-6882-01A | 3-gene | p.G659D | 260 | G184D |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EI-6917-01A | 5-gene | p.E88K | 260 | E88K |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-EO-A3B0-01A | 3-gene | p.N603T | 260 | N128T |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-F5-6814-01A | 5-gene | p.L72F | 260 | L72F |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-FI-A2D5-01A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-HU-A4HD-01A | 5-gene | p.T3A | 260 | T3A |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-IB-7651-01A | 3-gene | p.P667S | 260 | P192S |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-IR-A3LL-01A | 5-gene | p.E97Q | 260 | E97Q |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-L5-A8NM-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-RP-A695-06A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000265708_77458080_39607263 | TCGA-WE-A8K4-01A | 3-gene | p.R713K | 260 | R238K |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-13-2071-01A | 3-gene | p.I656T | 260 | I181T |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-29-1774-01A | 3-gene | p.C635F | 260 | C160F |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-2W-A8YY-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-37-3792-01A | 3-gene | p.G625C | 260 | G150C |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-38-4629-01A | 3-gene | p.P688L | 260 | P213L |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-38-4631-01A | 3-gene | p.C616F | 260 | C141F |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-63-5131-01A | 3-gene | p.P733A | 260 | P258A |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-68-7755-01A | 3-gene | p.K630Q | 260 | K155Q |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AA-A024-01A | 3-gene | p.C621Y | 260 | C146Y |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AB-2883-03A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AD-5900-01A | 5-gene | p.G18D | 260 | G18D |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AF-A56K-01A | 5-gene | p.A7V | 260 | A7V |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AJ-A3EL-01A | 3-gene | p.V626A | 260 | V151A |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AN-A046-01A | 5-gene | p.L112I | 260 | L112I |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AP-A051-01A | 3-gene | p.N603D | 260 | N128D |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AP-A1DK-01A | 5-gene | p.S115G | 260 | S115G |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AX-A0J0-01A | 3-gene | p.F695L | 260 | F220L |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-AY-4070-01A | 3-gene | p.L640V | 260 | L165V |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-BF-AAP0-06A | 3-gene | p.F690Y | 260 | F215Y |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-BQ-5892-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-BS-A0UV-01A | 3-gene | p.D623Y | 260 | D148Y |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-CA-6717-01A | 3-gene | p.R605I | 260 | R130I |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-CW-5587-01A | 3-gene | p.P667L | 260 | P192L |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-DA-A960-01A | 3-gene | p.R605K | 260 | R130K |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-DK-A1AD-01A | 3-gene | p.Q604E | 260 | Q129E |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-DK-A6AW-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EB-A85J-01A | 3-gene | p.S682F | 260 | S207F |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EE-A29D-06A | 3-gene | p.D619N | 260 | D144N |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EE-A2GH-06A | 3-gene | p.A665T | 260 | A190T |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EI-6882-01A | 3-gene | p.G659D | 260 | G184D |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EI-6917-01A | 5-gene | p.E88K | 260 | E88K |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-EO-A3B0-01A | 3-gene | p.N603T | 260 | N128T |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-F5-6814-01A | 5-gene | p.L72F | 260 | L72F |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-FI-A2D5-01A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-HU-A4HD-01A | 5-gene | p.T3A | 260 | T3A |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-IB-7651-01A | 3-gene | p.P667S | 260 | P192S |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-IR-A3LL-01A | 5-gene | p.E97Q | 260 | E97Q |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-L5-A8NM-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-RP-A695-06A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000379853_77458080_39607263 | TCGA-WE-A8K4-01A | 3-gene | p.R713K | 260 | R238K |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-13-2071-01A | 3-gene | p.I656T | 260 | I181T |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-29-1774-01A | 3-gene | p.C635F | 260 | C160F |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-2W-A8YY-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-37-3792-01A | 3-gene | p.G625C | 260 | G150C |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-38-4629-01A | 3-gene | p.P688L | 260 | P213L |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-38-4631-01A | 3-gene | p.C616F | 260 | C141F |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-63-5131-01A | 3-gene | p.P733A | 260 | P258A |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-68-7755-01A | 3-gene | p.K630Q | 260 | K155Q |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AA-A024-01A | 3-gene | p.C621Y | 260 | C146Y |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AB-2883-03A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AD-5900-01A | 5-gene | p.G18D | 260 | G18D |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AF-A56K-01A | 5-gene | p.A7V | 260 | A7V |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AJ-A3EL-01A | 3-gene | p.V626A | 260 | V151A |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AN-A046-01A | 5-gene | p.L112I | 260 | L112I |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AP-A051-01A | 3-gene | p.N603D | 260 | N128D |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AP-A1DK-01A | 5-gene | p.S115G | 260 | S115G |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AX-A0J0-01A | 3-gene | p.F695L | 260 | F220L |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-AY-4070-01A | 3-gene | p.L640V | 260 | L165V |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-BF-AAP0-06A | 3-gene | p.F690Y | 260 | F215Y |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-BQ-5892-01A | 3-gene | p.R674H | 260 | R199H |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-BS-A0UV-01A | 3-gene | p.D623Y | 260 | D148Y |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-CA-6717-01A | 3-gene | p.R605I | 260 | R130I |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-CW-5587-01A | 3-gene | p.P667L | 260 | P192L |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-DA-A960-01A | 3-gene | p.R605K | 260 | R130K |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-DK-A1AD-01A | 3-gene | p.Q604E | 260 | Q129E |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-DK-A6AW-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EB-A85J-01A | 3-gene | p.S682F | 260 | S207F |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EE-A29D-06A | 3-gene | p.D619N | 260 | D144N |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EE-A2GH-06A | 3-gene | p.A665T | 260 | A190T |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EI-6882-01A | 3-gene | p.G659D | 260 | G184D |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EI-6917-01A | 5-gene | p.E88K | 260 | E88K |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-EO-A3B0-01A | 3-gene | p.N603T | 260 | N128T |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-F5-6814-01A | 5-gene | p.L72F | 260 | L72F |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-FI-A2D5-01A | 3-gene | p.R674C | 260 | R199C |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-HU-A4HD-01A | 5-gene | p.T3A | 260 | T3A |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-IB-7651-01A | 3-gene | p.P667S | 260 | P192S |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-IR-A3LL-01A | 5-gene | p.E97Q | 260 | E97Q |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-L5-A8NM-01A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-RP-A695-06A | 3-gene | p.D724N | 260 | D249N |
| ENST00000308488_ENST00000521880_77458080_39607263 | TCGA-WE-A8K4-01A | 3-gene | p.R713K | 260 | R238K |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
Top |
Fusion Gene Exprssed Samples for RSF1_ADAM2 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | BRCA | TCGA-XX-A899-01A | RSF1 | chr11 | 77458080 | - | ADAM2 | chr8 | 39607263 | - | |
| WashU | BRCA | TCGA-XX-A899-01A | RSF1 | chr11 | 77458081 | - | ADAM2 | chr8 | 39607263 | - | |
| cBioPortal | BRCA_TCGA_PAN_CAN_ATLAS_2018 | BRCA | TCGA-XX-A899-01 | RSF1 | chr11 | 77747036 | ADAM2 | chr8 | 39749744 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
Top |
Related Drugs for RSF1_ADAM2 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies