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Fusion gene:BRWD1_LCA5L (FusionGDB2 ID:HG54014TG150082) |
Fusion Gene Summary for BRWD1_LCA5L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BRWD1_LCA5L | Fusion gene ID: hg54014tg150082 | Hgene | Tgene | Gene symbol | BRWD1 | LCA5L | Gene ID | 54014 | 150082 |
| Gene name | bromodomain and WD repeat domain containing 1 | lebercilin LCA5 like | |
| Synonyms | C21orf107|CILD51|DCAF19|N143|WDR9|WRD9 | C21orf13 | |
| Cytomap | 21q22.2 | 21q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | bromodomain and WD repeat-containing protein 1WD repeat protein WDR9-form2WD repeat-containing protein 9transcriptional unit N143 | lebercilin-like proteinLCA5L, lebercilin likeleber congenital amaurosis 5-like protein | |
| Modification date | 20240411 | 20240305 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000333229, ENST00000342449, ENST00000380800, ENST00000341322, ENST00000470108, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 26 X 38 X 17=16796 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 3 X 12 X 6=216 |
| # samples | 110 | 21 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(110/16796*10)=-3.932542264423 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(21/216*10)=-0.0406419844973459 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BRWD1 [Title/Abstract] AND LCA5L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | BRWD1(40684766)-LCA5L(40816127), # samples:1 | ||
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Fusion Gene Breakpoints for BRWD1_LCA5L |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| BRWD1 | chr21 | 40636386 | LCA5L | chr21 | 40795416 |
| BRWD1 | chr21 | 40636386 | LCA5L | chr21 | 40801137 |
| BRWD1 | chr21 | 40636386 | LCA5L | chr21 | 40807499 |
| BRWD1 | chr21 | 40670358 | LCA5L | chr21 | 40792769 |
| BRWD1 | chr21 | 40636386 | LCA5L | chr21 | 40807468 |
| BRWD1 | chr21 | 40585406 | LCA5L | chr21 | 40801137 |
| BRWD1 | chr21 | 40585407 | LCA5L | chr21 | 40801137 |
| BRWD1 | chr21 | 40641825 | LCA5L | chr21 | 40795416 |
| BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40783728 |
| BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40795416 |
| BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40801137 |
| BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40807468 |
| BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40816127 |
| BRWD1 | chr21 | 39213481 | LCA5L | chr21 | 39429211 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for BRWD1_LCA5L |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| BRWD1-LCA5L | Promoter / Enhancer Hijacking M6 | Promoter swap alters lebercilin-like protein expression, perturbing primary ciliary trafficking and centrosome organization. | Cilia-directed therapies; standard chemotherapy | Carcinomas |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| BRWD1-LCA5L | Promoter / Enhancer Hijacking M6 | Promoter swap alters lebercilin-like protein expression, perturbing primary ciliary trafficking and centrosome organization. | Cilia-directed therapies; standard chemotherapy | Carcinomas |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
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Fusion Genomic Features for BRWD1_LCA5L |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - | 4.58e-03 | 9.95e-01 |
| BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - | 1.25e-06 | 1.00e+00 |
| BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - | 1.32e-07 | 1.00e+00 |
| BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - | 2.24e-05 | 1.00e+00 |
| BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - | 6.87e-10 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for BRWD1_LCA5L |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000485895 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000333229 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000485895 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000342449 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000485895 | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40801137 | - |
| 5CDS-5UTR | ENST00000380800 | ENST00000485895 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40807499 | - |
| Frame-shift | ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| Frame-shift | ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40670357 | - | LCA5L | chr21 | 40792769 | - |
| In-frame | ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| In-frame | ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40636385 | - | LCA5L | chr21 | 40795416 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 2213 | 1222 |
| ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 2213 | 1222 |
| ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 2213 | 1191 |
| ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 526 | 310 |
| ENST00000341322 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 349 | 677 |
| ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1964 | 1191 |
| ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1964 | 1191 |
| ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1964 | 1222 |
| ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 277 | 677 |
| ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1984 | 1222 |
| ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1984 | 1222 |
| ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 1984 | 1191 |
| ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 297 | 677 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000470108 | ENST00000288350 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0 | 540 |
| ENST00000470108 | ENST00000358268 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0 | 540 |
| ENST00000470108 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0 | 720 |
| ENST00000470108 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 0 | 540 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000333229 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.28e-06 | 1.00e+00 |
| ENST00000333229 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.27e-06 | 1.00e+00 |
| ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.28e-06 | 1.00e+00 |
| ENST00000333229 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 2.45e-04 | 1.00e+00 |
| ENST00000341322 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 2.54e-04 | 1.00e+00 |
| ENST00000342449 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 8.98e-06 | 1.00e+00 |
| ENST00000342449 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 8.96e-06 | 1.00e+00 |
| ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 8.98e-06 | 1.00e+00 |
| ENST00000342449 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 2.92e-04 | 1.00e+00 |
| ENST00000380800 | ENST00000288350 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.34e-06 | 1.00e+00 |
| ENST00000380800 | ENST00000358268 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.36e-06 | 1.00e+00 |
| ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40636385 | LCA5L | chr21 | 40795416 | 9.34e-06 | 1.00e+00 |
| ENST00000380800 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 3.04e-04 | 1.00e+00 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000470108 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0.00e+00 | 6.02e-03 |
| ENST00000470108 | ENST00000288350 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0.00e+00 | 6.02e-03 |
| ENST00000470108 | ENST00000358268 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40795416 | 0.00e+00 | 6.27e-03 |
| ENST00000470108 | ENST00000380671 | BRWD1 | chr21 | 40684766 | LCA5L | chr21 | 40816127 | 0.00e+00 | 1.03e-03 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
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Fusion Protein Retained/Non-Retained Functional Features for BRWD1_LCA5L |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
| No matching images found for ${hg}_${tg}. |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 184_223 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 1 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 226_265 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 2 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 268_311 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 3 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 322_365 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 4 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 366_405 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 5 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 424_463 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 6 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 466_506 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 7 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 514_553 | 628.3333333333334 | 2321.0 | Repeat | Note=WD 8 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1277_1289 | 628.3333333333334 | 2321.0 | Compositional bias | Acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1443_1454 | 628.3333333333334 | 2321.0 | Compositional bias | Polar residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1455_1464 | 628.3333333333334 | 2321.0 | Compositional bias | Basic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1475_1496 | 628.3333333333334 | 2321.0 | Compositional bias | Polar residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1497_1509 | 628.3333333333334 | 2321.0 | Compositional bias | Low complexity |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1520_1529 | 628.3333333333334 | 2321.0 | Compositional bias | Polar residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1535_1548 | 628.3333333333334 | 2321.0 | Compositional bias | Low complexity |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1549_1561 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1676_1687 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1701_1712 | 628.3333333333334 | 2321.0 | Compositional bias | Polar residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1715_1728 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1751_1769 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1821_1832 | 628.3333333333334 | 2321.0 | Compositional bias | Acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 2054_2069 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 2114_2139 | 628.3333333333334 | 2321.0 | Compositional bias | Basic and acidic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 2140_2165 | 628.3333333333334 | 2321.0 | Compositional bias | Polar residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 814_824 | 628.3333333333334 | 2321.0 | Compositional bias | Low complexity |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 854_867 | 628.3333333333334 | 2321.0 | Compositional bias | Low complexity |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 907_918 | 628.3333333333334 | 2321.0 | Compositional bias | Basic residues |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1157_1264 | 628.3333333333334 | 2321.0 | Domain | Bromo 1 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1313_1418 | 628.3333333333334 | 2321.0 | Domain | Bromo 2 |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1271_1304 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1434_1593 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1670_1805 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1817_1839 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 1862_1899 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 2014_2077 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 2112_2184 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 668_691 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 809_867 | 628.3333333333334 | 2321.0 | Region | Disordered |
| Hgene | BRWD1 | chr21:40636385 | chr21:40795416 | ENST00000333229 | Q9NSI6 | 17 | 42 | 895_925 | 628.3333333333334 | 2321.0 | Region | Disordered |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Fusion Transcript Sequence for BRWD1_LCA5L |
| In-frame Fusion Transcript Sequences. |
>BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416 length=3942nt Breakpoint=2213nt AGGTCTTTGCCTCCGCGTCACTTTCTCCTCATCGAGTCCCCGGAGGCAGAGAGCTGAGCGAGGTTCGCCTCCCCGGGCGGGACACGAGCTCCGGTCCTCTCTTGGCGCAAACCCCCGCCCCCCGCGGAGGGACTACTTTTCGTCTCCCGC GGAGGAACTACTTCCTCCCCCGCGGAGGCGTCGGTCCAGGCGGCGCGCACGGTATGGCGGCGGCGGCGGCGGCGGCGGCGCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTC GCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGA GCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAA AGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGT GAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTG TGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATAC AATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTC CACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCAC AGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAAC AGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGT TGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGG CAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCT GATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATT CTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTG GAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTAC AGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAA GGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAA AATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCT TCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCAC AAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGA GGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACC AAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACA AAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTC TGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAA AGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTAT TTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000333229_ENST00000358268_40636385_40795416 length=3926nt Breakpoint=2213nt AGGTCTTTGCCTCCGCGTCACTTTCTCCTCATCGAGTCCCCGGAGGCAGAGAGCTGAGCGAGGTTCGCCTCCCCGGGCGGGACACGAGCTCCGGTCCTCTCTTGGCGCAAACCCCCGCCCCCCGCGGAGGGACTACTTTTCGTCTCCCGC GGAGGAACTACTTCCTCCCCCGCGGAGGCGTCGGTCCAGGCGGCGCGCACGGTATGGCGGCGGCGGCGGCGGCGGCGGCGCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTC GCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGA GCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAA AGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGT GAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTG TGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATAC AATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTC CACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCAC AGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAAC AGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGT TGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGG CAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCT GATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATT CTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTG GAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTAC AGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAA GGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAA AATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCT TCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCAC AAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGA GGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACC AAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACA AAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTC TGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAA AGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTAT TTAAATATAATCAATATCCTAATGCA >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416 length=3942nt Breakpoint=2213nt AGGTCTTTGCCTCCGCGTCACTTTCTCCTCATCGAGTCCCCGGAGGCAGAGAGCTGAGCGAGGTTCGCCTCCCCGGGCGGGACACGAGCTCCGGTCCTCTCTTGGCGCAAACCCCCGCCCCCCGCGGAGGGACTACTTTTCGTCTCCCGC GGAGGAACTACTTCCTCCCCCGCGGAGGCGTCGGTCCAGGCGGCGCGCACGGTATGGCGGCGGCGGCGGCGGCGGCGGCGCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTC GCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGA GCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAA AGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGT GAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTG TGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATAC AATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTC CACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCAC AGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAAC AGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGT TGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGG CAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCT GATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATT CTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTG GAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTAC AGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAA GGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAA AATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCT TCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCAC AAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGA GGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACC AAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACA AAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTC TGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAA AGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTAT TTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40684766_40816127 length=2890nt Breakpoint=526nt AGGTCTTTGCCTCCGCGTCACTTTCTCCTCATCGAGTCCCCGGAGGCAGAGAGCTGAGCGAGGTTCGCCTCCCCGGGCGGGACACGAGCTCCGGTCCTCTCTTGGCGCAAACCCCCGCCCCCCGCGGAGGGACTACTTTTCGTCTCCCGC GGAGGAACTACTTCCTCCCCCGCGGAGGCGTCGGTCCAGGCGGCGCGCACGGTATGGCGGCGGCGGCGGCGGCGGCGGCGCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTC GCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGA GCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGAGAAGCACCAAAAGAGGCAAACTGAGATGCAGACAAATGATCATCCGTATGCTGATCATTTTGAATAGTTTTT TAAAATATATTCTTTCTTTAAAAAGAGACCAAAACCTGTCAAAAAAATACTACCGTGGAAAGCTCATAAATACTACAGTGTGAAGAACCCTGTGCTTATCTTCAGTTTATCATCAGACATCTTAGGGAAGTTTAATAAAGAACACCAGGA GAATTGAGAATTAAATGAAAAGGTAAATCCTTTTAAAGACCTCAGAAGATGGATCTGTTTGTTTCAATCTGCTTTTGAGGTTGTTTGCTATGTCTTTGGCTGATCTAACAAAAACAAATATAGATGAGCATTTCTTCGGCGTGGCATTAG AAAACAATAGGAGGTCTGCAGCATGCAAGAGAAGCCCAGGCACAGGCGATTTTTCACGGAACAGTAATGCTTCCAATAAGAGTGTTGATTATAGCAGATCTCAGTGCTCCTGTGGAAGTTTAAGTTCTCAGTATGATTATTCAGAAGACT TTCTCTGTGATTGTTCAGAAAAGGCTATTAATAGAAATTATTTAAAGCAGCCTGTGGTAAAAGAAAAGGAGAAGAAAAAGTATAATGTTTCTAAAATCTCCCAATCTAAAGGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGA ATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAG AAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGG AAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAA TGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTC AACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAA GTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGG ATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAA AAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAA GAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTG ACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAG GCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTT AAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000341322_ENST00000380671_40684766_40816127 length=2713nt Breakpoint=349nt GCGTCGGTCCAGGCGGCGCGCACGGTATGGCGGCGGCGGCGGCGGCGGCGGCGCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGC CATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAA GAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGAGAAGCACCAAAAGAGGCAAACTGAGATGCAGACAAATGATCATCCGTATGCTGATCATTTTGAATAGTTTTTTAAAATATATTCTTTCTTTAAAAAGAG ACCAAAACCTGTCAAAAAAATACTACCGTGGAAAGCTCATAAATACTACAGTGTGAAGAACCCTGTGCTTATCTTCAGTTTATCATCAGACATCTTAGGGAAGTTTAATAAAGAACACCAGGAGAATTGAGAATTAAATGAAAAGGTAAA TCCTTTTAAAGACCTCAGAAGATGGATCTGTTTGTTTCAATCTGCTTTTGAGGTTGTTTGCTATGTCTTTGGCTGATCTAACAAAAACAAATATAGATGAGCATTTCTTCGGCGTGGCATTAGAAAACAATAGGAGGTCTGCAGCATGCA AGAGAAGCCCAGGCACAGGCGATTTTTCACGGAACAGTAATGCTTCCAATAAGAGTGTTGATTATAGCAGATCTCAGTGCTCCTGTGGAAGTTTAAGTTCTCAGTATGATTATTCAGAAGACTTTCTCTGTGATTGTTCAGAAAAGGCTA TTAATAGAAATTATTTAAAGCAGCCTGTGGTAAAAGAAAAGGAGAAGAAAAAGTATAATGTTTCTAAAATCTCCCAATCTAAAGGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCC ATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGC TTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAG AAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGA GCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTG AGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAAT CAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTAT CAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAA GAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAA CTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTA AGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGG AGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTC TGGTTTGATATAA >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416 length=3693nt Breakpoint=1964nt CGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCG GTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGC TCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAA GGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCA GCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATT AAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTAC ATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGG CGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTAT CCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTT TATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCT GGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTT TTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTA TGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGG CTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGG ACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACA TCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAA CCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGAC TTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAA AGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAAC TGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGA AGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGA TGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCA TAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTT TGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGT AAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000342449_ENST00000358268_40636385_40795416 length=3677nt Breakpoint=1964nt CGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCG GTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGC TCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAA GGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCA GCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATT AAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTAC ATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGG CGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTAT CCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTT TATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCT GGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTT TTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTA TGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGG CTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGG ACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACA TCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAA CCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGAC TTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAA AGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAAC TGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGA AGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGA TGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCA TAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTT TGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGT AAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCA >BRWD1_LCA5L_ENST00000342449_ENST00000380671_40636385_40795416 length=3693nt Breakpoint=1964nt CGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCG GTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTCTTGTCCAATAAGCATGTGGC TCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGACTGCAGGCACACAGTTTGGAA GGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCATTTCCAGGAACTATGTATCA GCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAATGGCCGCTTGTTATCTACATT AAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAAGGACACACAGGATCAATTAC ATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTCACTGAAAAGCCTAGGCCAGG CGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCACACTGATAAAGTAGATAGTAT CCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTATCTTCCGAAGAGGAAAGGTT TATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACATGCTGATGAAGTATTTGTTCT GGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGAGCTGTGTTTGACTGTAAGTT TTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTTATTAGAGATTCTAATAATTA TGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAACATTTGATTCCACAGCTGGG CTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGG ACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACA TCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAA CCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGAC TTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAA AGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAAC TGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGA AGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGA TGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCA TAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTT TGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGT AAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000342449_ENST00000380671_40684766_40816127 length=2641nt Breakpoint=277nt CGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAGCTGTACTTCCTTATCGCCCG GTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGAGAAGCACCAAAAGAGGCAAAC TGAGATGCAGACAAATGATCATCCGTATGCTGATCATTTTGAATAGTTTTTTAAAATATATTCTTTCTTTAAAAAGAGACCAAAACCTGTCAAAAAAATACTACCGTGGAAAGCTCATAAATACTACAGTGTGAAGAACCCTGTGCTTAT CTTCAGTTTATCATCAGACATCTTAGGGAAGTTTAATAAAGAACACCAGGAGAATTGAGAATTAAATGAAAAGGTAAATCCTTTTAAAGACCTCAGAAGATGGATCTGTTTGTTTCAATCTGCTTTTGAGGTTGTTTGCTATGTCTTTGG CTGATCTAACAAAAACAAATATAGATGAGCATTTCTTCGGCGTGGCATTAGAAAACAATAGGAGGTCTGCAGCATGCAAGAGAAGCCCAGGCACAGGCGATTTTTCACGGAACAGTAATGCTTCCAATAAGAGTGTTGATTATAGCAGAT CTCAGTGCTCCTGTGGAAGTTTAAGTTCTCAGTATGATTATTCAGAAGACTTTCTCTGTGATTGTTCAGAAAAGGCTATTAATAGAAATTATTTAAAGCAGCCTGTGGTAAAAGAAAAGGAGAAGAAAAAGTATAATGTTTCTAAAATCT CCCAATCTAAAGGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGAC TAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATC AGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACC TTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTT TAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAG TTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTG AAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAG ACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATG ACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATA GTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTG GATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAA ATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000380800_ENST00000288350_40636385_40795416 length=3713nt Breakpoint=1984nt GCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAG CTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTC TTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGAC TGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCA TTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAAT GGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAA GGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTC ACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCAC ACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTA TCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACAT GCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGA GCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTT ATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAA CATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCA AGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTA CCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAG AAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTG GCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACAT GACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATC GATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGA AGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGC ATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCC GGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGC AGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGA GACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000380800_ENST00000358268_40636385_40795416 length=3697nt Breakpoint=1984nt GCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAG CTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTC TTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGAC TGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCA TTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAAT GGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAA GGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTC ACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCAC ACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTA TCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACAT GCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGA GCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTT ATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAA CATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCA AGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTA CCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAG AAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTG GCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACAT GACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATC GATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGA AGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGC ATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCC GGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGC AGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGA GACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCA >BRWD1_LCA5L_ENST00000380800_ENST00000380671_40636385_40795416 length=3713nt Breakpoint=1984nt GCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAG CTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGTC TTGTCCAATAAGCATGTGGCTCCTGATCATCTTTTGCAAATCTGCCAGCGCATCGGTCCTATGTTGGATAAAGAAATTCCACCCAGTATTTCAAGAGTCACTTCTTTACTTGGTGCAGGAAGGCAGTCTTTGCTACGTACAGCAAAAGAC TGCAGGCACACAGTTTGGAAGGGCTCTGCCTTTGCTGCTCTTCATAGAGGAAGACCTCCTGAAATGCCAGTGAATTATGGTTCCCCACCAAATCTTGTGGAGATACATCGAGGAAAACAACTCACAGGGTGTTCCACTTTTAGTACAGCA TTTCCAGGAACTATGTATCAGCATATAAAAATGCACAGAAGGATTCTCGGACATCTATCTGCTGTTTACTGTGTAGCATTTGATAGGACAGGACATAGAATCTTTACAGGTTCAGATGACTGTTTGGTAAAGATTTGGTCAACACATAAT GGCCGCTTGTTATCTACATTAAGAGGTCATTCTGCAGAAATTTCAGATATGGCAGTAAACTATGAGAATACAATGATTGCTGCGGGGAGCTGTGATAAAATTATTAGAGTGTGGTGCTTGAGAACTTGTGCCCCAGTTGCTGTGCTCCAA GGACACACAGGATCAATTACATCTTTACAGTTTAGCCCGATGGCCAAAGGCTCTCAAAGATACATGGTTTCCACTGGTGCTGATGGGACAGTTTGCTTTTGGCAATGGGATTTAGAATCCTTAAAATTTAGCCCACGTCCCCTGAAGTTC ACTGAAAAGCCTAGGCCAGGCGTTCAAATGCTTTGTTCTTCTTTTAGTGTTGGTGGTATGTTTTTAGCCACAGGTAGTACTGATCATGTAATCAGAATGTATTTTTTGGGTTTTGAAGCACCCGAAAAAATCGCAGAACTTGAAAGCCAC ACTGATAAAGTAGATAGTATCCAATTTTGTAACAATGGTGATCGGTTCCTAAGTGGTAGCAGAGATGGAACAGCACGGATTTGGAGATTTGAGCAGTTAGAATGGAGGAGCATTTTATTGGATATGGCTACCAGAATCTCAGGGGACTTA TCTTCCGAAGAGGAAAGGTTTATGAAACCTAAAGTAACAATGATAGCTTGGAATCAAAATGATAGCATTGTTGTCACAGCTGTGAATGATCATGTCCTCAAAGTGTGGAATTCTTACACTGGACAACTGCTTCATAACTTAATGGGACAT GCTGATGAAGTATTTGTTCTGGAGACACATCCCTTTGATTCCAGAATTATGTTATCTGCAGGACATGATGGCAGCATATTTATATGGGATATTACAAAAGGTACCAAGATGAAACATTATTTTAATATGATTGAAGGACAAGGACATGGA GCTGTGTTTGACTGTAAGTTTTCACAGGATGGACAGCATTTTGCCTGTACAGATTCTCATGGGCACCTTCTGATATTTGGTTTTGGATGCAGCAAACCATATGAAAAGATTCCTGATCAGATGTTCTTCCATACTGACTATCGACCACTT ATTAGAGATTCTAATAATTATGTCTTAGATGAGCAAACTCAGCAGGCTCCTCATCTTATGCCTCCACCATTCTTGGTAGATGTAGATGGAAATCCTCATCCAACCAAGTATCAGAGATTAGTACCAGGCCGAGAAAATTCTGCAGATGAA CATTTGATTCCACAGCTGGGCTATGTGGCAACAAGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCA AGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTA CCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAG AAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTG GCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACAT GACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATC GATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGA AGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGC ATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCC GGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGC AGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGA GACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000380800_ENST00000380671_40684766_40816127 length=2661nt Breakpoint=297nt GCGCGCCTGAGAAGAGGGGACGCCAGCCCGGTCAGGCCTCGGCGCGGCCTACACGCTCCGCTCGCTCGCTCGCTCCCGCCTCCCGCCCCGCGCCCGGCCATGGCGGAGCCGTCGTCCGCCCGACGCCCGGTGCCTCTCATCGAGTCGGAG CTGTACTTCCTTATCGCCCGGTACCTATCGGCGGGCCCGTGTCGGAGAGCGGCCCAGGTGCTGGTGCAGGAGCTGGAGCAGTACCAGTTGTTGCCGAAGAGATTGGACTGGGAGGGCAACGAGCACAACAGGAGCTACGAGGAGTTGGAG AAGCACCAAAAGAGGCAAACTGAGATGCAGACAAATGATCATCCGTATGCTGATCATTTTGAATAGTTTTTTAAAATATATTCTTTCTTTAAAAAGAGACCAAAACCTGTCAAAAAAATACTACCGTGGAAAGCTCATAAATACTACAGT GTGAAGAACCCTGTGCTTATCTTCAGTTTATCATCAGACATCTTAGGGAAGTTTAATAAAGAACACCAGGAGAATTGAGAATTAAATGAAAAGGTAAATCCTTTTAAAGACCTCAGAAGATGGATCTGTTTGTTTCAATCTGCTTTTGAG GTTGTTTGCTATGTCTTTGGCTGATCTAACAAAAACAAATATAGATGAGCATTTCTTCGGCGTGGCATTAGAAAACAATAGGAGGTCTGCAGCATGCAAGAGAAGCCCAGGCACAGGCGATTTTTCACGGAACAGTAATGCTTCCAATAA GAGTGTTGATTATAGCAGATCTCAGTGCTCCTGTGGAAGTTTAAGTTCTCAGTATGATTATTCAGAAGACTTTCTCTGTGATTGTTCAGAAAAGGCTATTAATAGAAATTATTTAAAGCAGCCTGTGGTAAAAGAAAAGGAGAAGAAAAA GTATAATGTTTCTAAAATCTCCCAATCTAAAGGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAG GCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACC TCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAA ACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGC TATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGA CACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGA TCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAG ACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCAT GCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGG CAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAG TCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGA CTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
>BRWD1_LCA5L_ENST00000470108_ENST00000380671_40684766_40795416 length=1729nt Breakpoint=0nt GCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAAT TAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAA AAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGG AAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGA CAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAA AATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATG AAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGA AAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCA AAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGC ATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATG TCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGC CATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000470108_ENST00000288350_40684766_40795416 length=1729nt Breakpoint=0nt GCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAAT TAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAA AAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGG AAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGA CAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAA AATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATG AAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGA AAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCA AAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGC ATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATG TCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGC CATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA >BRWD1_LCA5L_ENST00000470108_ENST00000358268_40684766_40795416 length=1713nt Breakpoint=0nt GCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGCAAGGCTTCATAAAATTAAAGGACTAAAAAATGAAT TAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCTACCTCAAATTATGGCTAAACATCAGAATGAAGTAA AAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCAGAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGG AAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCTGGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGA CAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACATGACACAGAGGACTATCCAAAAGTTTCTTCAACAA AATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACATCGATCATAAAGAAAAATCAACTGAAATAAATCATG AAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGGAAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGA AAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAGCATGCAGAGAAATGGTGTGGATGACACACTTGGCA AAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGCCGGCAACATGAGGTACAGTCATAGTACAGGCAAGC ATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAGCAGTCTCATGGAAGAACTCTTTGGATCAGGCTATG TCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGGAGACTCTAAAGTAACTGTGGTAAATTCTATTAAGC CATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCA >BRWD1_LCA5L_ENST00000470108_ENST00000380671_40684766_40816127 length=2364nt Breakpoint=0nt GAGAAGCACCAAAAGAGGCAAACTGAGATGCAGACAAATGATCATCCGTATGCTGATCATTTTGAATAGTTTTTTAAAATATATTCTTTCTTTAAAAAGAGACCAAAACCTGTCAAAAAAATACTACCGTGGAAAGCTCATAAATACTAC AGTGTGAAGAACCCTGTGCTTATCTTCAGTTTATCATCAGACATCTTAGGGAAGTTTAATAAAGAACACCAGGAGAATTGAGAATTAAATGAAAAGGTAAATCCTTTTAAAGACCTCAGAAGATGGATCTGTTTGTTTCAATCTGCTTTT GAGGTTGTTTGCTATGTCTTTGGCTGATCTAACAAAAACAAATATAGATGAGCATTTCTTCGGCGTGGCATTAGAAAACAATAGGAGGTCTGCAGCATGCAAGAGAAGCCCAGGCACAGGCGATTTTTCACGGAACAGTAATGCTTCCAA TAAGAGTGTTGATTATAGCAGATCTCAGTGCTCCTGTGGAAGTTTAAGTTCTCAGTATGATTATTCAGAAGACTTTCTCTGTGATTGTTCAGAAAAGGCTATTAATAGAAATTATTTAAAGCAGCCTGTGGTAAAAGAAAAGGAGAAGAA AAAGTATAATGTTTCTAAAATCTCCCAATCTAAAGGCCAGAAGGAAATATCAGTTGAAAAAAAGCACACCTGGAATGCATCACTCTTTAATTCTCAAATCCATATGATTGCCCAAAGAAGAGATGCTATGGCTCATCGAATACTCTCAGC AAGGCTTCATAAAATTAAAGGACTAAAAAATGAATTAGCTGATATGCATCATAAATTGGAAGCCATCCTTACAGAAAACCAATTTTTGAAACAACTTCAGCTTAGGCATTTGAAAGCTATAGGAAAATATGAGAATTCACAAAATAATCT ACCTCAAATTATGGCTAAACATCAGAATGAAGTAAAAAATTTAAGGCAACTACTTAGGAAATCCCAGGAAAAGGAAAGAACTCTATCTAGGAAACTTAGAGAAACTGACAGCCAGTTACTGAAGACTAAAGATATCTTGCAGGCACTGCA GAAACTTTCTGAAGACAAAAACCTTGCAGAAAGGGAAGAACTCACTCATAAATTATCTATTATCACAACAAAAATGGACGCAAATGACAAAAAAATACAGAGCTTGGAAAAACAACTGAGGTTGAACTGCAGAGCCTTTAGCCGGCAGCT GGCTATTGAGACTCGGAAGACTTTAGCAGCTCAGACAGCTACCAAGACTCTGCAGGTGGAAGTAAAACACCTTCAACAAAAACTTAAGGAAAAGGATCGTGAGCTTGAAATTAAAAACATCTATAGTCATCGAATACTTAAAAATTTACA TGACACAGAGGACTATCCAAAAGTTTCTTCAACAAAATCAGTCCAAGCAGACAGAAAAATTTTGCCATTCACAAGTATGAGACACCAGGGAACCCAAAAATCAGATGTTCCACCTTTGACAACTAAGGGTAAAAAGGCAACAGGAAACAT CGATCATAAAGAAAAATCAACTGAAATAAATCATGAAATTCCTCACTGTGTGAATAAACTACCAAAGCAAGAGGATTCTAAGAGAAAATATGAAGATTTATCAGGGGAAGAGAAACATTTGGAAGTCCAAATACTGCTGGAGAATACTGG AAGACAAAAAGACAAAAAAGAAGACCAAGAAAAGAAAAACATTTTTGTGAAAGAAGAGCAAGAACTACCACCAAAAATAATTGAAGTTATTCATCCTGAAAGAGAAAGCAATCAAGAAGATGTTCTAGTAAGAGAAAAGTTTAAAAGAAG CATGCAGAGAAATGGTGTGGATGACACACTTGGCAAAGGCACTGCTCCCTACACGAAAGGCCCCCTCAGACAAAGAAGACATTACTCATTCACAGAAGCAACTGAAAACCTGCATCATGGGCTTCCTGCTTCAGGGGGGCCAGCCAATGC CGGCAACATGAGGTACAGTCATAGTACAGGCAAGCATCTCAGTAACAGAGAGGAAATGGAGCTAGAGCATTCTGACAGTGGGTATGAGCCCTCATTTGGTAAGTCTTCCAGAATAAAAGTGAAGGATACAACTTTCAGAGATAAGAAAAG CAGTCTCATGGAAGAACTCTTTGGATCAGGCTATGTCTTGAAAACTGACCAATCAAGTCCTGGTGTTGCAAAAGGCTCAGAGGAGCCTTTGCAAAGTAAGGAGTCGCATCCCCTGCCTCCCAGTCAGGCCTCCACCAGCCATGCTTTCGG AGACTCTAAAGTAACTGTGGTAAATTCTATTAAGCCATCGTCACCTACAGAAGGAAAAAGAAAAATAATTATTTAAATATAATCAATATCCTAATGCATTCTGGTTTGATATAA |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
Top |
Fusion Protein Sequence for BRWD1_LCA5L |
| In-frame Fusion Protein Sequences. |
>BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416 length=1222nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000358268_40636385_40795416 length=1222nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416 length=1191nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40684766_40816127 length=310nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKGDQ EYGPGDQSPGQGPEHHGPAEGLLSDGQVRAAGAEPGRPYIGDGGLHELGHHPDHAAGAGGQPHHADRRGEWPGGAGPAQPAARGRLCRGRELCAQPGGPAVTEVGRLEELAVPRRCAPPLPRDVLEGSCPLPTASCLCADPAGLRPAATL RLSPARPAWP >BRWD1_LCA5L_ENST00000341322_ENST00000380671_40684766_40816127 length=677nt MLLRLFAMSLADLTKTNIDEHFFGVALENNRRSAACKRSPGTGDFSRNSNASNKSVDYSRSQCSCGSLSSQYDYSEDFLCDCSEKAINRNYLKQPVVKEKEKKKYNVSKISQSKGQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRI LSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFS RQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLE NTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRD KKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416 length=1191nt MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000358268_40636385_40795416 length=1191nt MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000380671_40636385_40795416 length=1222nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000380671_40684766_40816127 length=677nt MLLRLFAMSLADLTKTNIDEHFFGVALENNRRSAACKRSPGTGDFSRNSNASNKSVDYSRSQCSCGSLSSQYDYSEDFLCDCSEKAINRNYLKQPVVKEKEKKKYNVSKISQSKGQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRI LSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFS RQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLE NTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRD KKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000380800_ENST00000288350_40636385_40795416 length=1222nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000380800_ENST00000358268_40636385_40795416 length=1222nt MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000380800_ENST00000380671_40636385_40795416 length=1191nt MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000380800_ENST00000380671_40684766_40816127 length=677nt MLLRLFAMSLADLTKTNIDEHFFGVALENNRRSAACKRSPGTGDFSRNSNASNKSVDYSRSQCSCGSLSSQYDYSEDFLCDCSEKAINRNYLKQPVVKEKEKKKYNVSKISQSKGQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRI LSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFS RQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLE NTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRD KKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII |
| N-Truncated Protein (5UTR-3CDS) Sequences |
>BRWD1_LCA5L_ENST00000470108_ENST00000288350_40684766_40795416 length=540nt MIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQS LEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLS GEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGK SSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000470108_ENST00000358268_40684766_40795416 length=540nt MIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQS LEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLS GEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGK SSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000470108_ENST00000380671_40684766_40795416 length=720nt MKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSRQFAAALEDLNEAIKLCPNNREIQRLLLRVEEECRQMQQPQQPPPPPQPQQQLPEEAEPEPQHEDIYSVQDIFEEEYLEQDV ENVSIGLQTEARPSQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSPTHQNSHYRPSPPHTSPAHQGGSYRFSPPPVGGQGKEYPSPPPSPLRRGPQYRASPPAESMSVYRSQSGSPVRYQQETSV SQLPGRPKSPLSKMAQRPYQMPQLPVAVPQQGLRLQPAKAQIVRSNQPSPAVHSSTVIPTGAYGQVAHSMASKYQSSQGDIGVSQSRLVYQGSIGGIVGDGRPVQHVQASLSAGAICQHGGLTKEDLPQRPSSAYRGGVRYSQTPQIGRS QSASYYPVCHSKLDLERSSSQLGSPDVSHLIRRPISVNPNEIKPHPPTPRPLLHSQSVGLRFSPSSNSISSTSNLTPTFRPSSSIQQMEIPLKPAYERSCDELSPVSPTQGGYPSEPTRSRTTPFMGIIDKTARTQQYPHLHQQNRTWAV SSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSRGDLLERVSQASSYPDVKVARTLPVAQAYQDNLYRQLSRDSRQGQTSPIKPKRPFVESNV >BRWD1_LCA5L_ENST00000470108_ENST00000380671_40684766_40816127 length=540nt MIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQS LEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLS GEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGK SSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII |
| C-Truncated Protein (5CDS-3UTR) Sequences |
Top |
Personalized Fusion Protein Sequence for BRWD1_LCA5L |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| CCLE All Mutated Fusion Protein Sequences |
>BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.N172S_1222_N724S length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTESQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.L609F_1222_L1161F length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVFKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.L175F_1222_L727F length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFFKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.E467D_1222_E1019D length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQDLPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.I278T_1222_I830T length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKTQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.G579D_1222_G1131D length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFDKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_both_p.R565Q-p.R666I_1222_R596Q;R1218I length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYQPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKIKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.K247R_1222_K799R length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQRLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.Q498H_1222_Q1050H length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ 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TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETESQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.R424K_1222_R976K length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKKKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000288350_40636385_40795416_3-gene_p.G394R_1222_G946R length=1222AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQ IMAKHQNEVKNLRQLLRKSQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDT EDYPKVSSTKSVQADRKILPFTSMRHQGTQKSDVPPLTTKGKKATRNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQ RNGVDDTLGKGTAPYTKGPLRQRRHYSFTEATENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDS KVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.P621S_1191_P652S length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLISQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.E398D_1191_E429D length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFDQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.P555A_1191_P586A length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIADQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.I771M_1191_I802M length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIMGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.Y45C_1191_Y76C length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQCQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.S653I_1191_S684I length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESIILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.R322G_1191_R353G length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPGPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.M178I_1191_M209I length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKIHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.I14M_1191_I45M length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLMESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.V325I_1191_V356I length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGIQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.L681P_1191_L712P length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGPSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.I634F_1191_I665F length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVFEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.C533R_1191_C564R length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFARTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.Y19H;p.C118Y_1191_Y50H;C149Y length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELHFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDYR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.S69P_1191_S100P length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLPNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.F591L_1191_F622L length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPLLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.V429I_1191_V460I length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKITMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.S96N_1191_S127N length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPNISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.L158R_1191_L189R length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQRTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.R565Q_1191_R596Q length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYQPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.P584S_1191_P615S length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQASHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.I394V_1191_I425V length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARVWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.A615S_1191_A646S length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSSDEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.R219C_1191_R250C length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGCLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.L13P_1191_L44P length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPPIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.R219G_1191_R250G length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGGLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.S232P_1191_S263P length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEIPDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.H199D_1191_H230D length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGDRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000333229_ENST00000380671_40636385_40795416_5-gene_p.K316T_1191_K347T length=1191AA MRRGDASPVRPRRGLHAPLARSLPPPAPRPAMAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCR HTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGH TGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLTFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSS EEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIR DSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQM HQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHEIRDPLMQWLGKHVDSEGEIKSGQLSLRFVSSYVSEVEITPS CIPVVTNMEAFSSEHFNLEIYRQNLQTKQLGKVILFAEVTPTTMRLLDGLMFQTPQEMGLIVIAARQTEGKGRGGNVWLSPVGCALSTLLISIPLRSQLGQRIPFVQHLMSVAVVEAVRSIPEYQDINLRVKWPNDIYYSDLMKIGGVLV NSTLMGETFYILIGCGFNVTNSNPTICINDLITEYNKQHKAELKPLRADYLIARVVTVLEKLIKEFQDKGPNSVLPLYYRYWVHSGQQVHLGSAEGPKVSIVGLDDSGFLQVHQEGGEVVTVHPDGNSFDMLRNLILPKRR >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.P621S_1191_P621S length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLISQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.E398D_1191_E398D length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFDQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.N172S_1191_N693S length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTESQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.P555A_1191_P555A length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIADQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.L609F_1191_L1130F length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVFKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.Y45C_1191_Y45C length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQCQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.R322G_1191_R322G length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPGPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.M178I_1191_M178I length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKIHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.I14M_1191_I14M length=1191AA MAEPSSARRPVPLMESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.V325I_1191_V325I length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGIQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.L175F_1191_L696F length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFFKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.C533R_1191_C533R length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFARTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.Y19H;p.C118Y_1191_Y19H;C118Y length=1191AA MAEPSSARRPVPLIESELHFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDYRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.S69P_1191_S69P length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLPNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.F591L_1191_F591L length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPLLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.V429I_1191_V429I length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKITMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.S96N_1191_S96N length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPNISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.E467D_1191_E988D length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQDLPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.L158R_1191_L158R length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQRTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.I278T_1191_I799T length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKTQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.G579D_1191_G1100D length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFDKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_both_p.R565Q-p.R666I_1191_R565Q;R1187I length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYQPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKIKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.K247R_1191_K768R length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQRLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.Q498H_1191_Q1019H length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMHRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.D232E_1191_D753E length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETESQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.P584S_1191_P584S length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQASHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.I394V_1191_I394V length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARVWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.A615S_1191_A615S length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSSDEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.R219C_1191_R219C length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGCLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.L13P_1191_L13P length=1191AA MAEPSSARRPVPPIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.R219G_1191_R219G length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGGLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.R424K_1191_R945K length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKKKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.S232P_1191_S232P length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEIPDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.H199D_1191_H199D length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGDRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_3-gene_p.G394R_1191_G915R length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATRNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII >BRWD1_LCA5L_ENST00000342449_ENST00000288350_40636385_40795416_5-gene_p.K316T_1191_K316T length=1191AA MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLV EIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCF WQWDLESLKFSPRPLTFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVL KVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPH PTKYQRLVPGRENSADEHLIPQLGYVATSQKEISVEKKHTWNASLFNSQIHMIAQRRDAMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYENSQNNLPQIMAKHQNEVKNLRQLLRKSQEKERTLSRKLR ETDSQLLKTKDILQALQKLSEDKNLAEREELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTEDYPKVSSTKSVQADRKILPFTSMRHQGTQK SDVPPLTTKGKKATGNIDHKEKSTEINHEIPHCVNKLPKQEDSKRKYEDLSGEEKHLEVQILLENTGRQKDKKEDQEKKNIFVKEEQELPPKIIEVIHPERESNQEDVLVREKFKRSMQRNGVDDTLGKGTAPYTKGPLRQRRHYSFTEA TENLHHGLPASGGPANAGNMRYSHSTGKHLSNREEMELEHSDSGYEPSFGKSSRIKVKDTTFRDKKSSLMEELFGSGYVLKTDQSSPGVAKGSEEPLQSKESHPLPPSQASTSHAFGDSKVTVVNSIKPSSPTEGKRKIII |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-000024 | 3-gene | p.N172S | 1222 | N724S |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-000195 | 3-gene | p.L609F | 1222 | L1161F |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-000867 | 3-gene | p.L175F | 1222 | L727F |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-000996 | 3-gene | p.E467D | 1222 | E1019D |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001029 | 3-gene | p.I278T | 1222 | I830T |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001060 | 3-gene | p.G579D | 1222 | G1131D |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001081 | both | p.R565Q-p.R666I | 1222 | R596Q;R1218I |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001377 | 3-gene | p.K247R | 1222 | K799R |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001414 | 3-gene | p.Q498H | 1222 | Q1050H |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001518 | 3-gene | p.D232E | 1222 | D784E |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-001982 | 3-gene | p.R424K | 1222 | R976K |
| ENST00000333229_ENST00000288350_40636385_40795416 | ACH-002309 | 3-gene | p.G394R | 1222 | G946R |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000019 | 5-gene | p.P621S | 1191 | P652S |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000021 | 5-gene | p.E398D | 1191 | E429D |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000177 | 5-gene | p.P555A | 1191 | P586A |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000298 | 5-gene | p.I771M | 1191 | I802M |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000426 | 5-gene | p.Y45C | 1191 | Y76C |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000565 | 5-gene | p.S653I | 1191 | S684I |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000706 | 5-gene | p.R322G | 1191 | R353G |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000840 | 5-gene | p.M178I | 1191 | M209I |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000849 | 5-gene | p.I14M | 1191 | I45M |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000853 | 5-gene | p.V325I | 1191 | V356I |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000898 | 5-gene | p.L681P | 1191 | L712P |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000930 | 5-gene | p.I634F | 1191 | I665F |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000937 | 5-gene | p.C533R | 1191 | C564R |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000970 | 5-gene | p.Y19H;p.C118Y | 1191 | Y50H;C149Y |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000986 | 5-gene | p.S69P | 1191 | S100P |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000990 | 5-gene | p.F591L | 1191 | F622L |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000991 | 5-gene | p.V429I | 1191 | V460I |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000995 | 5-gene | p.S96N | 1191 | S127N |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-000999 | 5-gene | p.L158R | 1191 | L189R |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001081 | 5-gene | p.R565Q | 1191 | R596Q |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001567 | 5-gene | p.P584S | 1191 | P615S |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001610 | 5-gene | p.I394V | 1191 | I425V |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001613 | 5-gene | p.A615S | 1191 | A646S |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001647 | 5-gene | p.R219C | 1191 | R250C |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001669 | 5-gene | p.L13P | 1191 | L44P |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001814 | 5-gene | p.R219G | 1191 | R250G |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-001991 | 5-gene | p.S232P | 1191 | S263P |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-002163 | 5-gene | p.H199D | 1191 | H230D |
| ENST00000333229_ENST00000380671_40636385_40795416 | ACH-002886 | 5-gene | p.K316T | 1191 | K347T |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000019 | 5-gene | p.P621S | 1191 | P621S |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000021 | 5-gene | p.E398D | 1191 | E398D |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000024 | 3-gene | p.N172S | 1191 | N693S |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000177 | 5-gene | p.P555A | 1191 | P555A |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000195 | 3-gene | p.L609F | 1191 | L1130F |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000426 | 5-gene | p.Y45C | 1191 | Y45C |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000706 | 5-gene | p.R322G | 1191 | R322G |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000840 | 5-gene | p.M178I | 1191 | M178I |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000849 | 5-gene | p.I14M | 1191 | I14M |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000853 | 5-gene | p.V325I | 1191 | V325I |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000867 | 3-gene | p.L175F | 1191 | L696F |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000937 | 5-gene | p.C533R | 1191 | C533R |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000970 | 5-gene | p.Y19H;p.C118Y | 1191 | Y19H;C118Y |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000986 | 5-gene | p.S69P | 1191 | S69P |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000990 | 5-gene | p.F591L | 1191 | F591L |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000991 | 5-gene | p.V429I | 1191 | V429I |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000995 | 5-gene | p.S96N | 1191 | S96N |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000996 | 3-gene | p.E467D | 1191 | E988D |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-000999 | 5-gene | p.L158R | 1191 | L158R |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001029 | 3-gene | p.I278T | 1191 | I799T |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001060 | 3-gene | p.G579D | 1191 | G1100D |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001081 | both | p.R565Q-p.R666I | 1191 | R565Q;R1187I |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001377 | 3-gene | p.K247R | 1191 | K768R |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001414 | 3-gene | p.Q498H | 1191 | Q1019H |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001518 | 3-gene | p.D232E | 1191 | D753E |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001567 | 5-gene | p.P584S | 1191 | P584S |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001610 | 5-gene | p.I394V | 1191 | I394V |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001613 | 5-gene | p.A615S | 1191 | A615S |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001647 | 5-gene | p.R219C | 1191 | R219C |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001669 | 5-gene | p.L13P | 1191 | L13P |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001814 | 5-gene | p.R219G | 1191 | R219G |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001982 | 3-gene | p.R424K | 1191 | R945K |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-001991 | 5-gene | p.S232P | 1191 | S232P |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-002163 | 5-gene | p.H199D | 1191 | H199D |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-002309 | 3-gene | p.G394R | 1191 | G915R |
| ENST00000342449_ENST00000288350_40636385_40795416 | ACH-002886 | 5-gene | p.K316T | 1191 | K316T |
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Fusion Gene Exprssed Samples for BRWD1_LCA5L |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| CCLE | Embryonal Carcinoma | NTERA2CLD1 | BRWD1 | chr21 | 40636386 | - | LCA5L | chr21 | 40795416 | - | |
| CCLE | Embryonal Carcinoma | NTERA2CLD1 | BRWD1 | chr21 | 40636386 | - | LCA5L | chr21 | 40801137 | - | |
| CCLE | Embryonal Carcinoma | NTERA2CLD1 | BRWD1 | chr21 | 40636386 | - | LCA5L | chr21 | 40807499 | - | |
| CCLE | Embryonal Carcinoma | NTERA2CLD1 | BRWD1 | chr21 | 40670358 | - | LCA5L | chr21 | 40792769 | - | |
| CCLE | Embryonal Carcinoma | NTERA2CLD1 | BRWD1 | chr21 | 40636386 | - | LCA5L | chr21 | 40807468 | - | |
| ChimerDB | BRCA | TCGA-A8-A08P-01A | BRWD1 | chr21 | 40585406 | - | LCA5L | chr21 | 40801137 | - | |
| ChimerDB | BRCA | TCGA-A8-A08P-01A | BRWD1 | chr21 | 40585407 | - | LCA5L | chr21 | 40801137 | - | |
| TCGAfusionPortal | BRCA | TCGA-A8-A08P-01A | BRWD1 | chr21 | 40585407 | - | LCA5L | chr21 | 40801137 | - | |
| WashU | BRCA | TCGA-A8-A08P-01A | BRWD1 | chr21 | 40585407 | - | LCA5L | chr21 | 40801137 | - | |
| cBioPortal | CCLE_BROAD_2019 | MIXED | HCC202_BREAST | BRWD1 | chr21 | 40641825 | LCA5L | chr21 | 40795416 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | KPL1_BREAST | BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40783728 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | KPL1_BREAST | BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40795416 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | KPL1_BREAST | BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40801137 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | KPL1_BREAST | BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40807468 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | KPL1_BREAST | BRWD1 | chr21 | 40684767 | LCA5L | chr21 | 40816127 | ||
| cBioPortal | BRCA_TCGA_PAN_CAN_ATLAS_2018 | BRCA | TCGA-A8-A08P-01 | BRWD1 | chr21 | 39213481 | LCA5L | chr21 | 39429211 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
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Related Drugs for BRWD1_LCA5L |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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