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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:PRIM2_NKAIN2 (FusionGDB2 ID:HG5558TG154215)

Fusion Gene Summary for PRIM2_NKAIN2

Fusion gene summary

Fusion gene information	Fusion gene name: PRIM2_NKAIN2
	Fusion gene ID: hg5558tg154215
		Hgene	Tgene
	Gene symbol	PRIM2	NKAIN2
	Gene ID	5558	154215
	Gene name	DNA primase subunit 2	sodium/potassium transporting ATPase interacting 2
	Synonyms	PRIM2A\|p58	FAM77B\|NKAIP2\|TCBA\|TCBA1
	Cytomap	6p11.2	6q22.31
	Type of gene	protein-coding	protein-coding
	Description	DNA primase large subunitDNA primase 58 kDa subunitprimase (DNA) subunit 2primase, DNA, polypeptide 2 (58kDa)	sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 2Na+/K+ transporting ATPase interacting 2T-cell lymphoma breakpoint-associated target protein 1
	Modification date	20240411	20240403
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000389488, ENST00000607273,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 17 X 8 X 12=1632	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 14 X 33 X 13=6006
	# samples	27	40
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(27/163210)=-2.59560974492066 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(40/600610)=-3.90833256978243 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: PRIM2 [Title/Abstract] AND NKAIN2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	PRIM2(57190843)-NKAIN2(124676412), # samples:1

Fusion gene breakpoints across PRIM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across NKAIN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for PRIM2_NKAIN2

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
PRIM2	chr6	57190843	NKAIN2	chr6	57190843
PRIM2	chr6	57190843	NKAIN2	chr6	124676413
PRIM2	chr6	57326045	NKAIN2	chr6	124355267

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for PRIM2_NKAIN2

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
PRIM2-NKAIN2	Promoter / Enhancer Hijacking M6		PRIM2 DNA primase promoter drives NKAIN2 expression, accelerating lagging-strand DNA synthesis alongside sodium/potassium-transporting ATPase interaction.		DNA synthesis inhibitors; ion transport modulators		Hyperproliferative epithelial carcinomas

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
PRIM2-NKAIN2	Promoter / Enhancer Hijacking M6		PRIM2 DNA primase promoter drives NKAIN2 expression, accelerating lagging-strand DNA synthesis alongside sodium/potassium-transporting ATPase interaction.		DNA synthesis inhibitors; ion transport modulators		Hyperproliferative epithelial carcinomas	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 28381166; Title: Downregulation of microRNA-181d had suppressive effect on pancreatic cancer development through inverse regulation of KNAIN2.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	PRIM2	GO:0006269	DNA replication, synthesis of primer	8026492
Hgene	PRIM2	GO:0006270	DNA replication initiation	26975377

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Fusion Genomic Features for PRIM2_NKAIN2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+	4.08e-06	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for PRIM2_NKAIN2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000389488	ENST00000368416	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
3UTR-3CDS	ENST00000389488	ENST00000368417	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
3UTR-3CDS	ENST00000389488	ENST00000545433	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
3UTR-3CDS	ENST00000389488	ENST00000546092	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
3UTR-3UTR	ENST00000389488	ENST00000476571	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
5CDS-3UTR	ENST00000607273	ENST00000476571	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
In-frame	ENST00000607273	ENST00000368416	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
In-frame	ENST00000607273	ENST00000368417	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
In-frame	ENST00000607273	ENST00000545433	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+
In-frame	ENST00000607273	ENST00000546092	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676412	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000607273	ENST00000368416	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	546	2108
ENST00000607273	ENST00000368417	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	546	290
ENST00000607273	ENST00000545433	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	546	241
ENST00000607273	ENST00000546092	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	546	310

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000607273	ENST00000368416	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	6.39e-03	9.94e-01
ENST00000607273	ENST00000368417	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	6.47e-03	9.94e-01
ENST00000607273	ENST00000545433	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	1.56e-03	9.98e-01
ENST00000607273	ENST00000546092	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	4.95e-03	9.95e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000607273	ENST00000476571	PRIM2	chr6	57190843	NKAIN2	chr6	124676412	0.00e+00	1.88e-01

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Fusion Protein Retained/Non-Retained Functional Features for PRIM2_NKAIN2

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

NKAIN2

chr6:57190843

chr6:124676412

ENST00000368416

Q5VXU1

153_173

64.0

189.0

Transmembrane

Helical

Tgene

NKAIN2

chr6:57190843

chr6:124676412

ENST00000368416

Q5VXU1

62_82

64.0

189.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

NKAIN2

chr6:57190843

chr6:124676412

ENST00000368416

Q5VXU1

1_23

64.0

189.0

Transmembrane

Helical

Tgene

NKAIN2

chr6:57190843

chr6:124676412

ENST00000368416

Q5VXU1

35_55

64.0

189.0

Transmembrane

Helical

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for PRIM2_NKAIN2

In-frame Fusion Transcript Sequences.

>PRIM2_NKAIN2_ENST00000607273_ENST00000368416_57190843_124676412 length=1400nt 
 Breakpoint=546nt
GGTTTCATATGAACTCTCCCGCCACCCGGGAACAGTGGCTGCCACCGTTTGTGTTTTCCCGAGTTTGAATTCTTGCAGGTGACCAAGATGGAGTTTTCTGGAAGAAAGTGGAGGAAGCTGAGGTTGGCAGGTGACCAGAGGAATGCTTCC
TACCCTCATTGCCTTCAGTTTTACTTGCAGCCACCTTCTGAAAACATATCTTTAATAGAATTTGAAAACTTGGCTATTGATAGAGTTAAATTGTTAAAATCAGTTGAAAATCTTGGAGTGAGCTATGTGAAAGGAACTGAACAATACCAG
AGTAAGTTGGAGAGTGAGCTTCGGAAGCTCAAGTTTTCCTACAGAGAAAACTTAGAAGATGAATATGAACCACGAAGAAGAGATCATATTTCTCATTTTATTTTGCGGCTTGCTTATTGCCAGTCTGAAGAACTTAGACGCTGGTTCATT
CAACAAGAAATGGATCTCCTTCGATTTAGATTTAGTATTTTACCCAAGGATAAAATTCAGGATTTCTTAAAGGATAGCCAATTGCAGTTTGAGGCTTATGCTGTCTGGCTAGTCCTCTGGGTTACGTGGAATGTGTTTGTTATCTGCTTC
TATTTGGAGGCTGGGGACCTCTCAAAGGAAACAGACCTTATCCTGACTTTTAATATATCAATGCACCGATCTTGGTGGATGGAGAATGGACCAGGATGTACGGTGACGTCAGTGACACCTGCCCCAGACTGGGCCCCAGAAGACCATCGC
TACATCACGGTCTCAGGGTGTTTGCTGGAGTACCAGTACATAGAAGTGGCTCATAGTTCCCTCCAGATTGTCCTCGCAGTAAGTGTTGGCAGCCAACCGCTCCTTCTAGTGCCTCTGGGGTTGTTTTATTTCTGTGCGAACTCAGTGCAC
ACAAATGGAATCTGTGGGTAAAGTGTGGCCTTTTTGCTTTTTCCTCATTAATGCGACTTTTAACAGGAAATCCTCAGGTTAAACTAAACCATCCTCTGGACTTAGTGTGCTGATTTTCTTCGACAATTAGTAAATACCCTTTGTTATCAT
CAGCATTTTACATAGGAAATCCAATCAGTCAAGATGTGATTACGTGACTTTTGGTAGACTTTTCCAAGGATTCTGAAGGGATGATCAGAGATTTTTTTCATAACGTTCTACAGTACTCAAAATTATAAGATTTCCATAAGTGTTTTCTCT
TTTAGTGCTTCTTTTGGCTGTGCTGCTAGCCCTGGGATTTCTCTTTTTCATTTGCCCTATCTCCTTCTTCCTTCCTAGATTTCTCCCAGGCACCATCCATCACCTTTAATCTCCCACTTTTTTTCCAGAAAAAATCACATTTTCTATAGA
TTCTAATTCTAAGACATTCATGCCCCCATTTTTCATAGTACTGTAACAAT

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412 length=3409nt 
 Breakpoint=546nt
GGTTTCATATGAACTCTCCCGCCACCCGGGAACAGTGGCTGCCACCGTTTGTGTTTTCCCGAGTTTGAATTCTTGCAGGTGACCAAGATGGAGTTTTCTGGAAGAAAGTGGAGGAAGCTGAGGTTGGCAGGTGACCAGAGGAATGCTTCC
TACCCTCATTGCCTTCAGTTTTACTTGCAGCCACCTTCTGAAAACATATCTTTAATAGAATTTGAAAACTTGGCTATTGATAGAGTTAAATTGTTAAAATCAGTTGAAAATCTTGGAGTGAGCTATGTGAAAGGAACTGAACAATACCAG
AGTAAGTTGGAGAGTGAGCTTCGGAAGCTCAAGTTTTCCTACAGAGAAAACTTAGAAGATGAATATGAACCACGAAGAAGAGATCATATTTCTCATTTTATTTTGCGGCTTGCTTATTGCCAGTCTGAAGAACTTAGACGCTGGTTCATT
CAACAAGAAATGGATCTCCTTCGATTTAGATTTAGTATTTTACCCAAGGATAAAATTCAGGATTTCTTAAAGGATAGCCAATTGCAGTTTGAGGCTTATGCTGTCTGGCTAGTCCTCTGGGTTACGTGGAATGTGTTTGTTATCTGCTTC
TATTTGGAGGCTGGGGACCTCTCAAAGGAAACAGACCTTATCCTGACTTTTAATATATCAATGCACCGATCTTGGTGGATGGAGAATGGACCAGGATGTACGGTGACGTCAGTGACACCTGCCCCAGACTGGGCCCCAGAAGACCATCGC
TACATCACGGTCTCAGGGTGTTTGCTGGAGTACCAGTACATAGAAGTGGCTCATAGTTCCCTCCAGATTGTCCTCGCACTGGCAGGTTTCATCTACGCCTGTTATGTTGTGAAATGTATAACTGAAGAAGAGGACAGCTTTGATTTCATA
GGTGGCTTTGACTCTTATGGCTATCAAGGGCCTCAGAAGACATCTCATTTACAACTACAGCCTATGTACATGTCAAAATAATACAGATGACTTCAGTATGTCAGCCCATGGACCTTTCAAAGAACTTTTTTCGCAGTGGCCTCCTGCATT
TCATGAAGAGCAAGAAGCAACTGAGTTTAAATACATACACGTATTAACAAAACAAATGCAAAGCCTCTACATACAACACTGACACACACACACACACACACGTGAGCACGCACACACCAATTCCACTTGACCTCCTCTTTCTAACTGAAA
CAGACAAATATGCAGGACACGCCCATCTTGGATTTCCTGAAAGCAGGCCCCTTTCTCCCAGGCCTTCGGAAAGTTCAGAAGGAGATGTGTTGATGCCCAACGGTTGCCGGCCATTGCTAACTCCTCTGCAGCCCAGCGGGTTGGCCTCTG
TGAGCTGGGAAGTCATCCAAGGCACATTAGTTTGAGAGCTCTGTCTTCTGCACTCCATACATCTTGACAGCACCACGGCTACTTAGGCAATGTAATTGCAAAAACAAACGAAACATGCCATGATGACCTTGTACCCGAAGTCCGAAATGG
CAGATTGTTTGCCCTAAAGGCTGTACCGTACATACTTGCCTTAACCCACCTACATTGTGTGCCCAAGAATCCCAGTGCAGACAGCCCCAAGCCACTTCCTTTAGGCTAACACACTGCTATTAATTCTAAATGAGTTCAAGCCTGTGTGTT
TCATGTCAAGGAACAAGACTGAATAGCTCAGCAGCTCCAGTGTGTCTGTATAAGAAAAGTGCCAGCTGTCAGCAAAGTGCTTTACCATAGAGCCTCCATGGTGGCCCAAAAGAGACAAGTAACAATAACAATATCTGTCATCTTTATAAT
TCTAAAATATGGTCTTCTGATGGGGTTGGGGGTGGGACAGAGTAAAACATTAATCTACTAAACTCACTAATCTACTGGAAGCAGAAAGCAGAAATGGCTTAACTCGCTGATTTTATTTATTGCACTCTAGGTGCTTTTATAAGTATCTAC
AATTGTCTTTTACTAACACAGAAACAGCTGTGGATTTCTATCAACAGAGGCCAACTGAATATGTATTAGCTATGTTTACTCTTTTATATCTAATTCAAATTGAAGACTCTACGTAGGTGAACTTTTTTTTCTAACTTCAGTGTACAAGAT
TATTTTTGGGTGGGTGGGGGGAGCAATAGTTACCTTGGTGAAATATTTGAGATCTTTTTGTGGTATTTGGGGGATCTGTTGTGTGTTAGAGTGTATTTCAACCCTCCTGTATTATTGTGGCAGAAAAACTGTGCTGTTAACGTAGTTGGC
AACAAGATGCCTTTGGAAACTTAATAGTAGGTCAATGTGTTTATGGAATATTCTGAACTCCTAGGAAATTTTGTTCTATATTTTAAAGCATTATTTGGTTTTCATTAGTGGAAAACATAATTAGCTCAGGCTTATCAGGAACTCAGATGA
GTCATATTTTTTCTTGGATACACCTGAGACATTAAACTCAATTTTTTAAAACTAACACACCATTCTTTAGTGCAGTGAAATTCAAAAGTTATAAATTGGCATGGAGCAAGTTTTTTCTTTGATTTCTATGAAGTTTCAGTTATTGGATTA
AACTACTTTAGACCTTAGCCCATTCGGATCTACATACACCAGTTCCATTACTGTGTTTGCATGGATGTCTGTAATATACACACACATATACATTTGAAAATGATAGAGGAACAAAGAGTTATCATTGGAACATAAACTATAAAAAAAGAT
TCCAGCACTCATGCTTGAATTTCCTCAGTGGGTTGTATGTTTGTCCATACATACATGTATAAAATAAACAATTGCAAACATGTCAGTGAAACCTCATATGACGCTTTTATAGTGACATGCATGTTTAATGTATGAGAAAAATATTTACCA
ATGTATTGTCCTTTGAGTCCTAAAATATAAATACTATACATGCCAGAAACTATTCTAATGTGACTTTTAATGTGACTATTAAAAATGAGGTTTCACTGTACATTCATGCTGTGATGCGATTTCACCTTATAGTACATGTATATGGGTACA
GAAAATAAACCCTCATATTCCTGCTTTAAGTTACAGCCAAGTTTTCACCAAATCACAACTATCATCACCACCAAAATTTTAAAAAACAGTAGTTGACTACTAAAAAGTAATCAGTGGACAGGTCATTTATGGGATCAGTAAGCACAGTAG
TGTGATTATATCTGGGAAAACATCTACAGTTGTACAGCTGTATCCTCCTCAAAATCCGGTGAAGAATGCTATTTTTCTAGGCTGAGCTTTTGTTATAAACTTAATATTCAGAAGGCAAGGGTTATGATCCTGATGTGTCCTTTTTTTTTG
CATTTGTTAATTCTGAATGTATTTTTAACAGAATGATTTTTTTGACTTACTAGTGTAATTTGCATTTTAAAAATAAATGGAAAAATACTTAAGTTTCTGAGCCATCCCT

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412 length=975nt 
 Breakpoint=546nt
GGTTTCATATGAACTCTCCCGCCACCCGGGAACAGTGGCTGCCACCGTTTGTGTTTTCCCGAGTTTGAATTCTTGCAGGTGACCAAGATGGAGTTTTCTGGAAGAAAGTGGAGGAAGCTGAGGTTGGCAGGTGACCAGAGGAATGCTTCC
TACCCTCATTGCCTTCAGTTTTACTTGCAGCCACCTTCTGAAAACATATCTTTAATAGAATTTGAAAACTTGGCTATTGATAGAGTTAAATTGTTAAAATCAGTTGAAAATCTTGGAGTGAGCTATGTGAAAGGAACTGAACAATACCAG
AGTAAGTTGGAGAGTGAGCTTCGGAAGCTCAAGTTTTCCTACAGAGAAAACTTAGAAGATGAATATGAACCACGAAGAAGAGATCATATTTCTCATTTTATTTTGCGGCTTGCTTATTGCCAGTCTGAAGAACTTAGACGCTGGTTCATT
CAACAAGAAATGGATCTCCTTCGATTTAGATTTAGTATTTTACCCAAGGATAAAATTCAGGATTTCTTAAAGGATAGCCAATTGCAGTTTGAGGCTTATGCTGTCTGGCTAGTCCTCTGGGTTACGTGGAATGTGTTTGTTATCTGCTTC
TATTTGGAGGCTGGGGACCTCTCAAAGGAAACAGACCTTATCCTGACTTTTAATATATCAATGCACCGATCTTGGTGGATGGAGAATGGACCAGGATGTACGGTGACGTCAGTGACACCTGCCCCAGACTGGGCCCCAGAAGACCATCGC
TACATCACGGTCTCAGGGTGTTTGCTGGAGTACCAGTACATAGAAGTGGCTCATAGTTCCCTCCAGATTGTCCTCGCACTGGCAGGTTTCATCTACGCCTGTTATGTTGTGAAATGTATAACTGAAGAAGAGGACAGCTTTGATTTCATA
GGTGGCTTTGACTCTTATGGCTATCAAGGGCCTCAGAAGACATCTCATTTACAACTACAGCCTATGTACATGTAA

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412 length=774nt 
 Breakpoint=546nt
GGTTTCATATGAACTCTCCCGCCACCCGGGAACAGTGGCTGCCACCGTTTGTGTTTTCCCGAGTTTGAATTCTTGCAGGTGACCAAGATGGAGTTTTCTGGAAGAAAGTGGAGGAAGCTGAGGTTGGCAGGTGACCAGAGGAATGCTTCC
TACCCTCATTGCCTTCAGTTTTACTTGCAGCCACCTTCTGAAAACATATCTTTAATAGAATTTGAAAACTTGGCTATTGATAGAGTTAAATTGTTAAAATCAGTTGAAAATCTTGGAGTGAGCTATGTGAAAGGAACTGAACAATACCAG
AGTAAGTTGGAGAGTGAGCTTCGGAAGCTCAAGTTTTCCTACAGAGAAAACTTAGAAGATGAATATGAACCACGAAGAAGAGATCATATTTCTCATTTTATTTTGCGGCTTGCTTATTGCCAGTCTGAAGAACTTAGACGCTGGTTCATT
CAACAAGAAATGGATCTCCTTCGATTTAGATTTAGTATTTTACCCAAGGATAAAATTCAGGATTTCTTAAAGGATAGCCAATTGCAGTTTGAGGCTTATGCTGTCTGGCTAGTCCTCTGGGTTACGTGGAATGTGTTTGTTATCTGCTTC
TATTTGGAGGCTGGGGACCTCTCAAAGCTGGCAGGTTTCATCTACGCCTGTTATGTTGTGAAATGTATAACTGAAGAAGAGGACAGCTTTGATTTCATAGGTGGCTTTGACTCTTATGGCTATCAAGGGCCTCAGAAGACATCTCATTTA
CAACTACAGCCTATGTACATGTAA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

>PRIM2_NKAIN2_ENST00000607273_ENST00000476571_57190843_124676412 length=546nt 
 Breakpoint=546nt
GGTTTCATATGAACTCTCCCGCCACCCGGGAACAGTGGCTGCCACCGTTTGTGTTTTCCCGAGTTTGAATTCTTGCAGGTGACCAAGATGGAGTTTTCTGGAAGAAAGTGGAGGAAGCTGAGGTTGGCAGGTGACCAGAGGAATGCTTCC
TACCCTCATTGCCTTCAGTTTTACTTGCAGCCACCTTCTGAAAACATATCTTTAATAGAATTTGAAAACTTGGCTATTGATAGAGTTAAATTGTTAAAATCAGTTGAAAATCTTGGAGTGAGCTATGTGAAAGGAACTGAACAATACCAG
AGTAAGTTGGAGAGTGAGCTTCGGAAGCTCAAGTTTTCCTACAGAGAAAACTTAGAAGATGAATATGAACCACGAAGAAGAGATCATATTTCTCATTTTATTTTGCGGCTTGCTTATTGCCAGTCTGAAGAACTTAGACGCTGGTTCATT
CAACAAGAAATGGATCTCCTTCGATTTAGATTTAGTATTTTACCCAAGGATAAAATTCAGGATTTCTTAAAGGATAGCCAATTGCAGTTTGAGGCT

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Fusion Protein Sequence for PRIM2_NKAIN2

In-frame Fusion Protein Sequences.

>PRIM2_NKAIN2_ENST00000607273_ENST00000368416_57190843_124676412 length=2108nt
MEAPSGSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCS
NHEKALRLLVELNKIPTVRAFLLSCMLLGGRKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINETKRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVY
CKRKSRVTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHMMMNKKVNLIKDRRRKLSTVPKCFLGNEFVAW
LLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYKSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADEE
MEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEVAGLQVGRKIYSINEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTLCFQIRGAAPPYVYAVGRGSEAMAAGLCAGQC
ILKVNGSNVMNDGAPEVLEHFQAFRSRREEALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSPMVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVEN
CRRLMALSSAIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHINLMEVSYPKTTPSVGRSFSIRFGRKPSLIGLDPEQGHLNPMSYTQHCITTMAAPSWKCLPAAEGDPQGQGLHDGSF
GPASGTLGQEDRGLSFLLKQEDREIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSGGSCDASLAEEASSLPLVSEESEMDRSDHGGIKKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSNSSYLGSDEMGS
GDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHFPMNHSLQEFKQKEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLALLKCTDTELQLRRDAIFCQALVAAVCTFSKQLLAALGYRY
NNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEK
VQQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSVGAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNLRVKDQMPQGAPRYFYP
FPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKT
KPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILP
MVPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSTEMPRTGNG
PMSVCGRC

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412 length=290nt
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412 length=241nt
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412 length=310nt
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for PRIM2_NKAIN2

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R18M_290_R31M length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.E90D_290_E103D length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLDDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R131T;p.D146H_290_R144T;D159H length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFTFSILPK
DKIQDFLKHSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.E57D_290_E70D length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVDNLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.K137N_290_K150N length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPN
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R129Q_290_R142Q length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.D99Y_290_D112Y length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRYHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.Q71K_290_Q84K length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R118C_290_R131C length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRCWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.V61E_290_V74E length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGESYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.M125I_290_M138I length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEIDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.L106F_290_L119F length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFIFRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R18M_290_R31M length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.D142Y_290_D155Y length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQYFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R129Q_290_R142Q length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.R9K_290_R22K length=290AA
MCFPEFEFLQVTKMEFSGRKWKKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.S113T_290_S126T length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQTEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.Q71K_290_Q84K length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000368417_57190843_124676412_5-gene_p.A20V_290_A33V length=290AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNVSYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLAVSVGSQPLLLVPLGLFYFCANSVHTNGICG

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R18M_241_R31M length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.E90D_241_E103D length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLDDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R131T;p.D146H_241_R144T;D159H length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFTFSILPK
DKIQDFLKHSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.E57D_241_E70D length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVDNLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.K137N_241_K150N length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPN
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R129Q_241_R142Q length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.D99Y_241_D112Y length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRYHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.Q71K_241_Q84K length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R118C_241_R131C length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRCWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.V61E_241_V74E length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGESYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.M125I_241_M138I length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEIDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.L106F_241_L119F length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFIFRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R18M_241_R31M length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.D142Y_241_D155Y length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQYFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R129Q_241_R142Q length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.R9K_241_R22K length=241AA
MCFPEFEFLQVTKMEFSGRKWKKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.S113T_241_S126T length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQTEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.Q71K_241_Q84K length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_3-gene_p.A158T_241_K193T length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSTLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000545433_57190843_124676412_5-gene_p.A20V_241_A33V length=241AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNVSYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSHLQLQPMYM

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R18M_310_R31M length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_both_p.E90D-p.E147G_310_E103D;E249G length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLDDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIGVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.Q191H_310_Q293H length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYHGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.S187C_310_S289C length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDCYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.D125H_310_D227H length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPHWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.E85G_310_E187G length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLGAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.M204T_310_M306T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPTYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.V117L_310_V219L length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTLTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R131T;p.D146H_310_R144T;D159H length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFTFSILPK
DKIQDFLKHSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.E57D_310_E70D length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVDNLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.K137N_310_K150N length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPN
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.T98I_310_T200I length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILIFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R129Q_310_R142Q length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.D99Y_310_D112Y length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRYHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.Q71K_310_Q84K length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.S152F_310_S254F length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSFLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.K91R_310_K193R length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSRETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R118C_310_R131C length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRCWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.N100K_310_N202K length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFKISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.R105Q_310_R207Q length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHQSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.A149V_310_A251V length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVVHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.V61E_310_V74E length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGESYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.M125I_310_M138I length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEIDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.W108C_310_W210C length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWCMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.V73I_310_V175I length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWITWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.Y65H_310_Y167H length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAHAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.I96T_310_I198T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLTLTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.W108C_310_W210C length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWCMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.L106F_310_L119F length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFIFRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R18M_310_R31M length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQMNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.G112R_310_G214R length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENRPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.D180N_310_D282N length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFNFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.Q144K_310_Q246K length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYKYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.D142Y_310_D155Y length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQYFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.F82L;p.V120A_310_F184L;V222A length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICLYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSATPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.E174K_310_E276K length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITKEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.G87A_310_G189A length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAADLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R129Q_310_R142Q length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLQFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.R9K_310_R22K length=310AA
MCFPEFEFLQVTKMEFSGRKWKKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.R132C_310_R234C length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHCYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.M204I_310_M306I length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPIYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.S113T_310_S126T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQTEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.Q71K_310_Q84K length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYKSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.A158T_310_A260T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLTLAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.A127T_310_A229T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWTPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.E92Q_310_E194Q length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKQTDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.P124L_310_P226L length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPALDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.S102L_310_S204L length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNILMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_3-gene_p.K195T_310_K297T length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQTTSH
LQLQPMYMSK

>PRIM2_NKAIN2_ENST00000607273_ENST00000546092_57190843_124676412_5-gene_p.A20V_310_A33V length=310AA
MCFPEFEFLQVTKMEFSGRKWRKLRLAGDQRNVSYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPK
DKIQDFLKDSQLQFEAYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFDFIGGFDSYGYQGPQKTSH
LQLQPMYMSK

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-05-4415-01A	5-gene	p.R18M	290	R31M
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-06-5416-01A	5-gene	p.E90D	290	E103D
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-A8-A07W-01A	5-gene	p.R131T;p.D146H	290	R144T;D159H
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-AA-A00N-01A	5-gene	p.E57D	290	E70D
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-AJ-A3EK-01A	5-gene	p.K137N	290	K150N
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-AP-A0LM-01A	5-gene	p.R129Q	290	R142Q
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-AX-A2HC-01A	5-gene	p.D99Y	290	D112Y
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-BF-A1PZ-01A	5-gene	p.Q71K	290	Q84K
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-CG-4442-01A	5-gene	p.R118C	290	R131C
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-CZ-4859-01A	5-gene	p.V61E	290	V74E
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-D3-A1Q1-06A	5-gene	p.M125I	290	M138I
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-DX-A6YS-01A	5-gene	p.L106F	290	L119F
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-E6-A1LX-01A	5-gene	p.R18M	290	R31M
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-EO-A22R-01A	5-gene	p.D142Y	290	D155Y
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-FI-A2D0-01A	5-gene	p.R129Q	290	R142Q
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-FI-A2D5-01A	5-gene	p.R9K	290	R22K
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-G4-6302-01A	5-gene	p.S113T	290	S126T
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-GF-A2C7-01A	5-gene	p.Q71K	290	Q84K
ENST00000607273_ENST00000368417_57190843_124676412	TCGA-VQ-AA6D-01A	5-gene	p.A20V	290	A33V
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-05-4415-01A	5-gene	p.R18M	241	R31M
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-06-5416-01A	5-gene	p.E90D	241	E103D
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-A8-A07W-01A	5-gene	p.R131T;p.D146H	241	R144T;D159H
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-AA-A00N-01A	5-gene	p.E57D	241	E70D
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-AJ-A3EK-01A	5-gene	p.K137N	241	K150N
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-AP-A0LM-01A	5-gene	p.R129Q	241	R142Q
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-AX-A2HC-01A	5-gene	p.D99Y	241	D112Y
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-BF-A1PZ-01A	5-gene	p.Q71K	241	Q84K
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-CG-4442-01A	5-gene	p.R118C	241	R131C
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-CZ-4859-01A	5-gene	p.V61E	241	V74E
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-D3-A1Q1-06A	5-gene	p.M125I	241	M138I
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-DX-A6YS-01A	5-gene	p.L106F	241	L119F
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-E6-A1LX-01A	5-gene	p.R18M	241	R31M
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-EO-A22R-01A	5-gene	p.D142Y	241	D155Y
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-FI-A2D0-01A	5-gene	p.R129Q	241	R142Q
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-FI-A2D5-01A	5-gene	p.R9K	241	R22K
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-G4-6302-01A	5-gene	p.S113T	241	S126T
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-GF-A2C7-01A	5-gene	p.Q71K	241	Q84K
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-HU-A4H8-01A	3-gene	p.A158T	241	K193T
ENST00000607273_ENST00000545433_57190843_124676412	TCGA-VQ-AA6D-01A	5-gene	p.A20V	241	A33V
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-05-4415-01A	5-gene	p.R18M	310	R31M
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-06-5416-01A	both	p.E90D-p.E147G	310	E103D;E249G
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-4Z-AA87-01A	3-gene	p.Q191H	310	Q293H
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-55-6712-01A	3-gene	p.S187C	310	S289C
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-58-8387-01A	3-gene	p.D125H	310	D227H
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-61-2087-01A	3-gene	p.E85G	310	E187G
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-91-6848-01A	3-gene	p.M204T	310	M306T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-91-7771-01A	3-gene	p.V117L	310	V219L
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-A8-A07W-01A	5-gene	p.R131T;p.D146H	310	R144T;D159H
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-AA-A00N-01A	5-gene	p.E57D	310	E70D
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-AJ-A3EK-01A	5-gene	p.K137N	310	K150N
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-AJ-A3EL-01A	3-gene	p.T98I	310	T200I
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-AP-A0LM-01A	5-gene	p.R129Q	310	R142Q
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-AX-A2HC-01A	5-gene	p.D99Y	310	D112Y
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-BF-A1PZ-01A	5-gene	p.Q71K	310	Q84K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-BF-AAP1-01A	3-gene	p.S152F	310	S254F
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-BR-8078-01A	3-gene	p.K91R	310	K193R
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-CG-4442-01A	5-gene	p.R118C	310	R131C
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-CG-4469-01A	3-gene	p.N100K	310	N202K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-CN-5365-01A	3-gene	p.R105Q	310	R207Q
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-CS-4943-01A	3-gene	p.A149V	310	A251V
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-CZ-4859-01A	5-gene	p.V61E	310	V74E
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-D3-A1Q1-06A	5-gene	p.M125I	310	M138I
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-D8-A13Z-01A	3-gene	p.W108C	310	W210C
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-D8-A142-01A	3-gene	p.V73I	310	V175I
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-D8-A1JP-01A	3-gene	p.Y65H	310	Y167H
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-D9-A3Z1-06A	3-gene	p.I96T	310	I198T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-DK-AA74-01A	3-gene	p.W108C	310	W210C
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-DX-A6YS-01A	5-gene	p.L106F	310	L119F
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-E6-A1LX-01A	5-gene	p.R18M	310	R31M
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-EE-A29V-06A	3-gene	p.G112R	310	G214R
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-EE-A2GR-06A	3-gene	p.D180N	310	D282N
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-EE-A3AD-06A	3-gene	p.Q144K	310	Q246K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-EO-A22R-01A	5-gene	p.D142Y	310	D155Y
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-EO-A3B0-01A	3-gene	p.F82L;p.V120A	310	F184L;V222A
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-ER-A2ND-06A	3-gene	p.E174K	310	E276K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-FF-8041-01A	3-gene	p.G87A	310	G189A
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-FI-A2D0-01A	5-gene	p.R129Q	310	R142Q
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-FI-A2D5-01A	5-gene	p.R9K	310	R22K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-FR-A726-01A	3-gene	p.R132C	310	R234C
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-FS-A1YY-06A	3-gene	p.M204I	310	M306I
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-G4-6302-01A	5-gene	p.S113T	310	S126T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-GF-A2C7-01A	5-gene	p.Q71K	310	Q84K
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-HU-A4H8-01A	3-gene	p.A158T	310	A260T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-IH-A3EA-01A	3-gene	p.A127T	310	A229T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-K4-A3WS-01A	3-gene	p.E92Q	310	E194Q
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-OR-A5KB-01A	3-gene	p.P124L	310	P226L
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-QC-A7B5-01A	3-gene	p.S102L	310	S204L
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-VQ-A91S-01A	3-gene	p.K195T	310	K297T
ENST00000607273_ENST00000546092_57190843_124676412	TCGA-VQ-AA6D-01A	5-gene	p.A20V	310	A33V

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for PRIM2_NKAIN2

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		LUSC	TCGA-O2-A52V-01A	PRIM2	chr6	57190843	+	NKAIN2	chr6	57190843	+
ChimerDB		LUSC	TCGA-O2-A52V	PRIM2	chr6	57190843	+	NKAIN2	chr6	57190843	+
WashU		LUSC	TCGA-O2-A52V-01A	PRIM2	chr6	57190843	+	NKAIN2	chr6	124676413	+
cBioPortal	LUSC_TCGA_PAN_CAN_ATLAS_2018	LUSC	TCGA-O2-A52V-01	PRIM2	chr6	57326045		NKAIN2	chr6	124355267

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for PRIM2_NKAIN2

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status