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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene Breakpoints

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness

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Fusion Genomic Features

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Fusion Gene ORF Annotations

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Fusion Protein Retained/Non-Retained Functional Features

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Fusion Transcript Sequences

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Fusion Protein Sequences

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Personalized Fusion Protein Sequences

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Fusion Gene Expressed Samples

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Related Drugs

Fusion gene:BIRC6_TTC27 (FusionGDB2 ID:HG57448TG55622)

Fusion Gene Summary for BIRC6_TTC27

check button Fusion gene summary
Fusion gene informationFusion gene name: BIRC6_TTC27
Fusion gene ID: hg57448tg55622
HgeneTgene
Gene symbol

BIRC6

TTC27

Gene ID

57448

55622

Gene namebaculoviral IAP repeat containing 6tetratricopeptide repeat domain 27
SynonymsAPOLLON|BRUCE-
Cytomap

2p22.3

2p22.3

Type of geneprotein-codingprotein-coding
Descriptionbaculoviral IAP repeat-containing protein 6BIR repeat-containing ubiquitin-conjugating enzymeRING-type E3 ubiquitin transferase BIRC6ubiquitin-conjugating BIR-domain enzyme apollontetratricopeptide repeat protein 27TPR repeat protein 27
Modification date2024040720240305
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000421745, ENST00000421745, 
Fusion gene scores* DoF score* DoF score (Degree of Frequency) = # partners X # break points X # disease types
24 X 28 X 22=14784		* DoF score (Degree of Frequency) = # partners X # break points X # disease types
8 X 27 X 13=2808
# samples 6032
** MAII score** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(60/14784*10)=-4.62293035092018
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(32/2808*10)=-3.1333991254172
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BIRC6 [Title/Abstract] AND TTC27 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBIRC6(32836649)-TTC27(33036090), # samples:1

check buttonFusion gene breakpoints across BIRC6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TTC27 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Fusion Gene Breakpoints for BIRC6_TTC27


check button RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbp
BIRC6chr232582554TTC27chr232582554
BIRC6chr232774548TTC27chr232774548
BIRC6chr232605358TTC27chr232605358
BIRC6chr232695369TTC27chr233002948
BIRC6chr232695369TTC27chr232695369
BIRC6chr232704685TTC27chr232704685
BIRC6chr232768608TTC27chr232768608
BIRC6chr232836649TTC27chr233036091


check button DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbpSV type
BIRC6chr232621143TTC27chr232969116DUP
BIRC6chr232661543TTC27chr232918720DUP
BIRC6chr232661543TTC27chr232940834DUP
BIRC6chr232654636TTC27chr232933095DUP
BIRC6chr232633569TTC27chr232904596DUP
BIRC6chr232633569TTC27chr233013822DUP
BIRC6chr232633569TTC27chr233039690DUP
BIRC6chr232633569TTC27chr232933095DUP
BIRC6chr232633569TTC27chr232960091DUP
BIRC6chr232666137TTC27chr232879162DUP
BIRC6chr232828468TTC27chr232931967DUP
BIRC6chr232807608TTC27chr232995486DUP
BIRC6chr232777703TTC27chr232971895DUP
BIRC6chr232645184TTC27chr232934001DUP
BIRC6chr232688454TTC27chr232875274DUP
BIRC6chr232767651TTC27chr232930348DUP
BIRC6chr232739147TTC27chr232872692DUP
BIRC6chr232738300TTC27chr232896055DUP
BIRC6chr232679732TTC27chr232861950DUP
BIRC6chr232691438TTC27chr232881819DUP
BIRC6chr232735881TTC27chr232861950DUP
BIRC6chr232744989TTC27chr232875069DUP
BIRC6chr232806385TTC27chr232977741DUP
BIRC6chr232806385TTC27chr232969116DUP
BIRC6chr232754986TTC27chr232897055DUP
BIRC6chr232754986TTC27chr232883196DUP
BIRC6chr232633690TTC27chr232918112DUP
BIRC6chr232678414TTC27chr232853192DEL
BIRC6chr232820054TTC27chr232999091DEL
BIRC6chr232755109TTC27chr232897055DEL
BIRC6chr232782763TTC27chr232961858DUP
BIRC6chr232810293TTC27chr232924202DUP
BIRC6chr232836649TTC27chr233036089DUP
BIRC6chr232624578TTC27chr232915356DEL
BIRC6chr232664574TTC27chr233042629DUP
BIRC6chr232654212TTC27chr232927992DUP
BIRC6chr232781405TTC27chr232916076DUP
BIRC6chr232832260TTC27chr233034057DUP
BIRC6chr232738045TTC27chr232899566DUP
BIRC6chr232787199TTC27chr232968519DUP
BIRC6chr232746129TTC27chr232913607DEL
BIRC6chr232703576TTC27chr232971021DEL
BIRC6chr232664574TTC27chr232961888DUP
BIRC6chr232779552TTC27chr232945650DUP
BIRC6chr232768661TTC27chr232915357DUP
BIRC6chr232765390TTC27chr232902085DUP
BIRC6chr232686961TTC27chr232988840DEL
BIRC6chr232769351TTC27chr232883197DUP
BIRC6chr232633690TTC27chr232961858DUP
BIRC6chr232838747TTC27chr232948602DUP
BIRC6chr232673976TTC27chr232965429DUP
BIRC6chr232688260TTC27chr232875305DUP
BIRC6chr232692591TTC27chr232983591DUP
BIRC6chr232818980TTC27chr232927992DUP
BIRC6chr232822816TTC27chr233012221DUP
BIRC6chr232842790TTC27chr233012221DUP
BIRC6chr232842790TTC27chr233042629DUP
BIRC6chr232782999TTC27chr232957000DUP
BIRC6chr232716012TTC27chr232968823DEL
BIRC6chr232838747TTC27chr233042517DUP
BIRC6chr232769506TTC27chr232874181DUP
BIRC6chr232843419TTC27chr233020535DUP
BIRC6chr232699800TTC27chr233023757DUP
BIRC6chr232738300TTC27chr232896058DUP
BIRC6chr232811944TTC27chr233045164DUP
BIRC6chr232841911TTC27chr233045355DUP


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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for BIRC6_TTC27


check button To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.
* We have 10 tumorigenic mechanism categories of fusion genes as shown below.
Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand FusionsAberrant Chimeric Transcription Factor / Fusion Transcription Factor ActivityEpigenetic Reprogramming / Histone Modifier DysregulationChromatin Remodeling DysregulationCondensate-Driven Transcriptional Rewiring / LLPPromoter / Enhancer HijackingDominant-Negative AntagonismCell Cycle / Checkpoint Bypass / RNA Processing DysregulationSubcellular Mislocalization / Spatial DysregulationNuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed
BIRC6-TTC27
Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation
M8		BIRC6 IAP domain fusion sustains continuous neutralization of pro-apoptotic caspases, conferring high chemoresistance.Smac mimetics (LCL161, birinapant); BH3 mimeticsChemoresistant solid tumors and hematologic malignancies

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed
BIRC6-TTC27
Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation
M8		BIRC6 IAP domain fusion sustains continuous neutralization of pro-apoptotic caspases, conferring high chemoresistance.Smac mimetics (LCL161, birinapant); BH3 mimeticsChemoresistant solid tumors and hematologic malignancies

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

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Fusion Genomic Features for BIRC6_TTC27


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BIRC6chr232695369+TTC27chr233002948+5.38e-049.99e-01


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).
genomic feature

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Fusion Gene ORF Annotations for BIRC6_TTC27

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32695369

+TTC27chr2

33002948

+

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)
ENST00000421745ENST00000317907BIRC6chr232836649TTC27chr233036090145281729

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score
ENST00000421745ENST00000317907BIRC6chr232836649TTC27chr2330360909.57e-061.00e+00

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

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Fusion Protein Retained/Non-Retained Functional Features for BIRC6_TTC27

check buttonProtein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.
fgviewer annotation
- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).
No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520453_486666.0844.0RepeatNote=TPR 1
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520492_525666.0844.0RepeatNote=TPR 2
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520527_560666.0844.0RepeatNote=TPR 3
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520561_594666.0844.0RepeatNote=TPR 4
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520596_628666.0844.0RepeatNote=TPR 5
TgeneTTC27chr2:32836649chr2:33036090ENST00000317907Q6P3X31520629_662666.0844.0RepeatNote=TPR 6


check button - Retained PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Fusion Transcript Sequence for BIRC6_TTC27

check button In-frame Fusion Transcript Sequences.
>BIRC6_TTC27_ENST00000421745_ENST00000317907_32836649_33036090 length=15175nt
Breakpoint=14528nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTGACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTG
GTGCTGCACCTCCCGGGACTGTCACTGAGCCGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGGGGGCGGGGGCGGCCGGGGTCTCAGAGTGGC
TGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACCACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGCTAAACCAGGTGGACAGGTGAAATGTCAGTATATCTCTGCTGTGGATAAAGTTATATTTGTGGATGATTATGCAGTAGGGTGTAGGAAGGACCTTAATGGAATCTTGTTGTTAGACACTGCTCTGCAAACTCCAGTTTCAA
AGCAGGATGATGTGGTTCAGCTTGAATTACCCGTTACAGAGGCACAGCAGCTCTTATCAGCATGTTTAGAAAAGGTAGATATTTCTAGTACAGAGGGTTATGATTTGTTCATCACACAGCTCAAAGATGGTTTAAAAAATACATCTCATG
AGACTGCAGCAAACCACAAAGTTGCTAAGTGGGCCACAGTTACATTTCATCTTCCTCATCATGTGTTGAAGTCCATTGCCAGTGCCATTGTAAATGAACTCAAGAAAATAAATCAAAATGTTGCTGCCTTACCTGTGGCGTCCTCAGTGA
TGGACAGATTGTCTTACCTCTTACCTAGTGCACGTCCAGAACTCGGAGTGGGGCCAGGCCGTTCTGTAGACAGATCACTGATGTATAGTGAAGCTAACAGACGGGAGACATTTACCTCATGGCCTCATGTAGGCTATAGGTGGGCACAAC
CAGATCCCATGGCTCAAGCTGGATTTTATCATCAGCCTGCCTCATCTGGAGATGATAGAGCCATGTGTTTTACTTGTAGTGTATGCCTCGTTTGTTGGGAACCTACTGATGAACCTTGGTCTGAACACGAAAGACATTCCCCAAACTGCC
CATTTGTGAAAGGTGAGCACACACAGAATGTGCCATTGTCAGTCACTCTTGCAACAAGTCCTGCACAGTTTCCTTGTACGGATGGAACTGACAGAATATCTTGCTTTGGGTCGGGGAGCTGCCCTCATTTTCTAGCTGCTGCAACTAAAC
GAGGAAAGATCTGCATATGGGATGTTTCCAAACTTATGAAGGTGCACTTAAAGTTTGAAATTAATGCCTATGATCCAGCAATTGTACAACAGCTTATTCTATCAGGAGACCCAAGCTCAGGAGTTGATTCAAGGAGACCAACTTTGGCGT
GGCTGGAGGACTCCTCTAGTTGCTCAGATATACCAAAATTGGAAGGAGATAGTGATGATTTACTGGAGGATTCAGACAGTGAAGAGCATTCCAGATCAGATTCTGTGACAGGGCATACATCACAGAAGGAAGCCATGGAAGTAAGCCTTG
ATATAACAGCACTCAGCATTCTCCAACAGCCAGAAAAACTTCAGTGGGAGATTGTTGCAAATGTGCTTGAAGATACTGTTAAGGATCTTGAAGAACTTGGGGCAAATCCTTGTTTAACAAACTCTAAGAGTGAAAAGACAAAGGAAAAGC
ACCAGGAGCAACACAACATTCCTTTTCCATGTTTATTAGCTGGAGGTTTATTAACATATAAATCTCCTGCTACCTCACCCATTAGTAGTAATTCTCACAGGTCACTGGATGGTTTAAGCAGAACTCAGGGTGAAAGTATATCAGAACAAG
GGTCAACTGACAATGAATCCTGCACTAATTCAGAACTAAATTCTCCTCTGGTAAGGAGGACTTTACCGGTTTTGCTTCTTTATAGCATCAAGGAATCTGATGAGAAAGCAGGAAAGATCTTTTCACAGATGAACAATATTATGAGTAAAA
GTTTGCATGATGATGGTTTTACTGTTCCACAGATTATTGAAATGGAGCTGGATAGTCAGGAGCAGTTGTTATTGCAGGATCCTCCTGTGACTTACATTCAGCAATTTGCAGATGCAGCAGCCAACCTTACCTCTCCGGATTCTGAGAAGT
GGAACTCTGTGTTTCCCAAGCCTGGGACTTTGGTTCAGTGCTTGAGGCTGCCAAAGTTTGCAGAGGAGGAGAATCTTTGTATAGACTCAATAACTCCTTGTGCTGACGGAATTCATTTGTTGGTAGGACTGCGGACATGCCCTGTTGAAT
CCTTGAGTGCAATAAATCAAGTAGAGGCCTTGAATAATTTAAATAAATTAAACTCTGCACTATGTAATAGACGGAAAGGTGAGCTGGAATCAAATCTTGCTGTAGTGAATGGTGCAAATATTAGTGTAATCCAACATGAATCACCAGCAG
ATGTACAGACTCCTTTAATAATTCAGCCTGAGCAGAGGAATGTTAGTGGTGGATATTTAGTGCTTTATAAAATGAATTATGCCACTCGGATAGTGACTTTAGAAGAGGAGCCAATAAAAATACAACATATCAAAGATCCCCAGGACACAA
TTACCTCGCTCATTTTGCTTCCACCCGATATATTGGATAATCGAGAGGATGACTGTGAGGAACCTATTGAGGACATGCAGTTAACCTCAAAGAATGGTTTTGAGAGAGAAAAAACGTCTGACATTTCTACTCTTGGACACCTGGTAATAA
CCACTCAGGGAGGATATGTAAAAATACTAGATCTTTCAAACTTTGAAATTTTGGCCAAAGTGGAGCCTCCCAAAAAGGAGGGCACTGAGGAACAGGACACATTTGTTTCTGTGATTTACTGTTCTGGCACAGACAGGCTGTGTGCATGCA
CCAAAGGTGGTGAGCTTCATTTTCTCCAAATTGGAGGAACCTGTGATGATATTGATGAAGCTGATATACTAGTGGATGGATCTCTTTCTAAAGGAATAGAACCATCTTCAGAAGGTTCCAAACCTTTATCAAATCCTTCAAGTCCTGGCA
TTTCAGGAGTTGATTTATTGGTGGACCAGCCATTCACCCTTGAAATCTTGACATCCCTAGTGGAGCTAACCCGCTTTGAGACTTTGACTCCAAGGTTTTCAGCGACTGTTCCTCCATGCTGGGTAGAAGTTCAACAAGAACAGCAGCAAA
GGAGGCATCCTCAACATTTGCATCAGCAACACCATGGTGATGCTGCTCAGCATACTCGAACTTGGAAACTACAGACCGACAGCAACAGCTGGGATGAACATGTATTTGAATTAGTACTACCTAAAGCTTGTATGGTTGGACATGTGGACT
TCAAATTCGTTTTGAACTCAAACATCACCAATATTCCACAGATACAAGTGACACTGCTGAAAAATAAAGCTCCAGGATTAGGGAAAGTCAATGCTCTTAACATTGAAGTGGAACAAAATGGGAAACCGTCCCTGGTTGATTTGAATGAAG
AAATGCAGCACATGGATGTAGAGGAATCACAGTGTCTTAGATTATGTCCATTTTTGGAGGATCATAAAGAAGACATTCTATGTGGGCCAGTATGGCTTGCTAGTGGCCTTGATCTATCAGGGCATGCTGGAATGTTGACGTTAACAAGCC
CCAAACTTGTTAAAGGTATGGCAGGAGGAAAATATCGTTCGTTTTTAATCCATGTCAAGGCAGTGAATGAAAGAGGAACAGAAGAGATTTGTAATGGTGGTATGCGTCCTGTAGTAAGGCTTCCATCCCTAAAACACCAGAGTAACAAGG
GTTATTCACTTGCTTCACTTTTGGCTAAAGTTGCAGCAGGCAAGGAAAAATCATCTAATGTTAAGAATGAAAATACAAGTGGCACCCGTAAATCTGAAAACCTCCGGGGCTGTGATTTACTTCAAGAGGTCTCAGTCACCATTCGAAGAT
TTAAGAAAACCTCAATTTCTAAGGAAAGAGTGCAACGATGTGCCATGTTACAGTTTTCAGAATTTCATGAGAAGCTTGTTAATACTCTTTGCAGAAAAACAGATGATGGCCAGATCACAGAACATGCCCAGAGCCTTGTGTTGGATACTC
TCTGTTGGTTAGCTGGAGTTCATTCAAATGGACCCGGAAGCTCAAAGGAAGGAAATGAGAACCTACTTTCAAAAACACGAAAATTTCTGTCAGACATCGTACGTGTTTGCTTCTTTGAGGCAGGACGAAGTATAGCCCATAAGTGTGCCC
GATTTCTAGCCTTGTGCATTAGTAATGGCAAATGTGACCCATGTCAACCAGCATTTGGACCTGTTCTGTTGAAGGCTTTACTTGATAATATGTCATTTTTACCTGCAGCAACAACTGGTGGTTCTGTCTATTGGTATTTTGTCTTACTGA
ATTATGTGAAAGATGAAGATCTGGCTGGATGCAGTACAGCTTGTGCATCTTTGCTTACTGCAGTGTCCAGACAGTTACAGGACAGGCTAACACCAATGGAGGCTTTACTTCAGACAAGATATGGATTATATAGCTCACCATTTGATCCAG
TCCTCTTTGATTTGGAGATGAGTGGCTCTTCTTGTAAAAATGTTTATAACAGCAGCATTGGTGTCCAGTCAGATGAAATTGATTTATCAGATGTCCTTTCAGGAAATGGAAAGGTCAGTAGTTGCACAGCTGCTGAGGGTAGTTTCACAT
CTCTCACTGGACTTTTGGAAGTTGAACCTCTGCACTTTACTTGTGTGTCAACTAGTGATGGAACCAGAATAGAAAGGGATGATGCAATGAGTTCCTTCGGGGTTACTCCTGCAGTAGGTGGACTATCATCTGGGACAGTTGGGGAAGCCT
CGACAGCCCTGAGTTCAGCAGCCCAGGTAGCTTTGCAGTCTCTCTCTCATGCAATGGCTTCAGCCGAGCAACAGCTACAGGTGCTGCAAGAGAAACAGCAGCAGCTTTTGAAGCTTCAGCAACAGAAAGCAAAGCTGGAAGCCAAGTTAC
ATCAGACAACAGCTGCAGCAGCTGCAGCAGCATCAGCAGTAGGTCCTGTTCACAACTCTGTGCCTTCCAACCCAGTGGCTGCCCCTGGATTCTTCATTCATCCATCTGATGTTATTCCACCCACTCCAAAAACAACACCTCTTTTTATGA
CTCCACCACTCACTCCACCCAATGAAGCAGTTTCCGTTGTGATTAATGCCGAACTTGCACAGCTTTTCCCAGGCTCAGTCATTGATCCCCCAGCAGTCAATCTTGCTGCACATAACAAAAATTCCAACAAGTCCAGAATGAATCCACTTG
GTTCTGGTCTAGCCCTTGCAATTTCTCATGCTTCACATTTTCTTCAACCTCCGCCTCACCAGTCCATTATTATAGAGCGAATGCATTCAGGAGCAAGAAGATTTGTGACCTTGGATTTTGGGAGGCCTATATTGTTGACTGATGTATTGA
TTCCCACTTGTGGAGACTTGGCCTCTTTGTCAATTGACATTTGGACATTAGGAGAAGAGGTGGATGGAAGGCGGTTGGTAGTGGCAACTGATATAAGCACTCATTCACTAATTCTTCATGACTTAATACCACCTCCCGTGTGCAGATTCA
TGAAGATCACTGTTATTGGACGTTACGGGAGTACAAATGCCAGAGCCAAAATCCCATTAGGATTTTACTATGGTCATACCTACATCTTGCCTTGGGAAAGTGAACTGAAGTTAATGCATGATCCTCTAAAGGGAGAGGGAGAATCTGCAA
ACCAGCCAGAAATTGACCAGCATTTAGCAATGATGGTTGCTTTGCAGGAGGATATACAGTGCAGGTATAACTTGGCTTGTCATCGTCTGGAAACCCTTTTGCAAAGTATTGATCTTCCTCCTCTAAACAGTGCTAACAATGCACAGTACT
TTTTACGAAAACCAGATAAGGCAGTTGAGGAAGACAGTAGGGTTTTTTCTGCTTATCAAGATTGTATTCAGCTACAGCTTCAACTAAATTTGGCTCATAATGCAGTGCAGAGGCTCAAAGTGGCGCTAGGTGCAAGCCGGAAGATGTTGA
GTGAAACATCAAATCCAGAAGATTTAATTCAGACATCTTCCACAGAGCAGTTACGTACTATCATCAGATATTTACTGGACACTTTGCTCAGCCTGCTTCATGCTTCTAATGGACACTCTGTTCCTGCAGTTTTGCAGAGCACATTTCATG
CCCAGGCCTGTGAAGAGCTCTTTAAACACTTGTGCATCAGTGGAACCCCAAAGATACGGTTACATACTGGTCTTCTTCTTGTTCAACTGTGTGGTGGTGAAAGGTGGTGGGGTCAATTTCTTTCTAATGTCCTTCAGGAATTGTACAATT
CGGAACAGCTTCTCATCTTTCCACAGGATAGGGTCTTCATGTTACTTTCCTGCATTGGTCAAAGATCACTTAGTAATAGTGGAGTATTAGAAAGCTTACTTAATCTCTTGGATAATTTATTGTCACCTCTTCAGCCACAGTTACCCATGC
ATAGGAGGACAGAAGGAGTACTAGATATTCCCATGATCAGTTGGGTTGTTATGCTGGTGTCCAGGTTGCTGGATTATGTGGCAACTGTTGAAGATGAAGCAGCAGCTGCAAAGAAACCTTTGAATGGTAATCAGTGGAGTTTTATTAACA
ATAATCTACACACTCAGAGCTTAAATAGATCTTCTAAAGGCAGCAGTAGCCTTGATAGATTATATTCCAGAAAAATCAGAAAGCAGCTTGTTCATCATAAACAGCAACTTAACCTACTAAAAGCAAAGCAGAAGGCATTGGTAGAACAGA
TGGAAAAAGAAAAAATACAAAGTAACAAAGGATCATCATATAAACTCCTGGTAGAACAAGCAAAACTAAAGCAGGCCACTTCAAAGCACTTTAAGGATTTAATTCGTTTACGTCGGACAGCAGAATGGTCCCGTTCTAATTTAGACACAG
AAGTTACAACAGCAAAAGAAAGTCCTGAGATAGAACCACTTCCATTTACTCTGGCCCATGAGCGTTGTATCTCAGTAGTCCAGAAACTTGTTCTGTTTCTTCTCTCCATGGACTTTACATGTCATGCAGATCTCTTATTGTTTGTTTGTA
AGGTTCTTGCACGCATTGCAAATGCCACGAGGCCAACTATTCATCTGTGTGAGATTGTGAACGAACCCCAGCTGGAAAGACTGCTGTTACTTTTGGTTGGAACTGACTTCAATAGAGGAGATATATCTTGGGGTGGTGCTTGGGCTCAGT
ATTCCTTAACTTGCATGCTACAAGATATTTTAGCAGGAGAATTACTGGCTCCAGTAGCCGCAGAAGCCATGGAGGAAGGAACAGTGGGTGATGATGTAGGTGCGACAGCTGGTGACTCTGATGACTCCCTTCAACAGTCCTCAGTTCAGT
TGCTGGAAACTATAGATGAACCTTTGACACATGACATAACAGGTGCACCTCCTCTGTCCTCTTTGGAAAAAGATAAAGAAATTGACCTTGAGTTACTTCAGGATCTAATGGAAGTTGACATTGATCCTTTAGATATTGATTTGGAAAAGG
ACCCTCTTGCAGCCAAGGTTTTTAAGCCAATAAGCAGTACATGGTATGATTATTGGGGTGCTGATTATGGGACCTACAATTACAACCCTTACATTGGAGGTCTGGGAATTCCTGTAGCAAAGCCACCAGCAAACACGGAGAAGAACGGAT
CACAGACAGTTAGCGTTTCAGTCTCTCAGGCCCTGGATGCTCGCCTAGAAGTTGGACTTGAACAGCAAGCAGAACTGATGTTGAAAATGATGTCTACTCTGGAGGCAGATTCCATTTTACAGGCATTAACAAATACATCTCCTACATTAT
CACAGTCTCCCACTGGAACAGATGATTCACTTCTAGGGGGTTTACAAGCAGCAAACCAAACCAGCCAGCTTATTATACAGTTATCATCTGTCCCAATGTTAAATGTTTGTTTCAACAAACTTTTTTCCATGCTTCAAGTCCATCATGTTC
AGTTGGAGTCACTTCTCCAATTGTGGCTCACACTGAGCCTGAATTCTAGTTCAACTGGAAACAAAGAAAATGGAGCAGACATATTTTTATATAATGCTAATAGGATACCTGTTATTTCATTAAATCAAGCATCAATAACTAGCTTTCTCA
CAGTGTTAGCTTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTTTCAGATC
CAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTC
AGATATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTA
TTTCTGCCGTGATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCGGGTGATG
CAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAG
ATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCA
TGGCAATGATAATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATGCTGCAGC
CAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGC
TCATATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACA
ATGCTGAAGGGATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCAGAGGAGG
CTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTC
CTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTA
CCACCTCTTCTGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCACCTACTG
CTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAG
CATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAAT
GGGTTAGTGATTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCATAGTTATG
AGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACT
ATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAA
CTGAATCACATTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATTGCCCAGT
CAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTT
CTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGC
GCACAGCAATTGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAACATTTCAG
GGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCC
GTACTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAA
ATGGATTTCAAGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCAGAGGCTG
CCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTG
TTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGA
TACTGGATGAATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTAACATCTA
CCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCC
ATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTCATATTCTTCAATCTCCATCAG
CCAATGTGCTTCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACTACACCTTTGACAACTGATGATGGTGTACTTCTAAGGCGGATGGCATTGGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCTTTGAGCC
ACCATTCCCCACGAGTTCCAAACTCTAGCGTGAATCAAACTGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAAGAACAACAGTTATATTGGGCCAAAGGGACTGGCTTTGGAACAGGCTCTACAGCTTCTGGGTGGGATG
TGGAACAAGCCTTAACTAAGCAAAGGCTGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTTCTTGCCAGTTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAGTCATCTCATGAGACTAGAGGGCAGAACAGTAATGCCC
TTCCTTCTGTACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATGTCATCTTATCTACGAAATGATTCAGTTCTGGACATGGCAAGACATGTGCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCTTCTTGTG
CTGCCATGGTGCCCCTATTGTTGCCCCTTTCTACAGAGAACGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTTGGTACATTGTTAGCCAAAATGAAGACCTGTGTTGATACCTATACCAACCGTTTAAGATCTAAAAGGG
AAAATGTTAAAACAGGAGTAAAACCAGATGCGTCTGATCAAGAACCAGAAGGACTTACTCTTTTGGTACCAGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACCAGTTTGCGGCAAGCAAATCAGGAAAAAAAACTGGGTG
AATACTCCAAGAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCACTTGAAGAAAAATATGTGGCTGTTATGAAGAAATTACAGTTTGATACGTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTTAAAGTAA
ATTACCACTACATGTCTCAGGTGAAAAATGCTAATGATGCGAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTGACGCTTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGTACGCTGTGATGAGGAGCGAC
TTGATATCATGAAGGTTCTAATAACTGGTCCAGCGGACACCCCTTATGCAAATGGCTGCTTTGAGTTTGATGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTGAATCTAGAGACAACTGGTGGTCATAGCGTGCGATTCA
ATCCAAACCTTTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGGCATGGAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCAAGCTTTTTGCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAGCCTTATT
TTAATGAACCGGGATATGAACGGTCTAGAGGCACTCCCAGTGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAAGCAACAGTTAAGTGGGCAATGCTAGAACAAATCAGAAACCCTTCACCATGTTTTAAAGAGGTAATAC
ACAAACATTTTTACTTGAAAAGAGTTGAGATAATGGCCCAATGTGAGGAGTGGATTGCGGATATCCAGCAGTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCATGCAGCAGCTCTCAAGGTCCTTAAAATTCTAGTCAGGG
CAGTGATTGATGGGATGACTGATCGAAGTGGAGATGTTGCAACTGGCCTCAAAGGAAAGCTGCAGGAGTTATTTGGCAGAGTGACTTCAAGAGTGACAAATGATGGAGAAATCTGGAGGCTGTATGCCCACGTATATGGAAATGGGCAGA
GTGAAAAGCCTGATGAAAATGAAAAGGCATTCCAGTGCCTCTCAAAGGCATACAAGTGTGACACCCAGTCCAATTGTTGGGAGAAAGATATTACATCATTTAAGGAAGTTGTTCAAAGAGCCTTAGGACTTGCACATGTGGCCATAAAAT
GCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGGGCTTGTTATCTAAAGCAAAGCAACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAG
CTATGGACACCTTAGTGACAGAGCTCCAAGACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCACCTGCTGGTAAAAGATACATCTGTATATCTGAAATGCAAGATATTGATTTTT
AAAATAAATTTGTTTTATGACTTAA


check button N-Truncated Transcript (5UTR-3CDS) Sequences

check button C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for BIRC6_TTC27

check button In-frame Fusion Protein Sequences.
>BIRC6_TTC27_ENST00000421745_ENST00000317907_32836649_33036090 length=1729nt
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGTIKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTAL
QTPVSKQDDVVQLELPVTEAQQLLSACLEKVDISSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPELGVGPGRSVDRSLMYSEANRRETFTSWPHVG
YRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKGEHTQNVPLSVTLATSPAQFPCTDGTDRISCFGSGSCPHFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPAIVQQLILSGDPSSGVDSR
RPTLAWLEDSSSCSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGANPCLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSNSHRSLDGLSRTQGE
SISEQGSTDNESCTNSELNSPLVRRTLPVLLLYSIKESDEKAGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDSQEQLLLQDPPVTYIQQFADAAANLTSPDSEKWNSVFPKPGTLVQCLRLPKFAEEENLCIDSITPCADGIHLLVGLR
TCPVESLSAINQVEALNNLNKLNSALCNRRKGELESNLAVVNGANISVIQHESPADVQTPLIIQPEQRNVSGGYLVLYKMNYATRIVTLEEEPIKIQHIKDPQDTITSLILLPPDILDNREDDCEEPIEDMQLTSKNGFEREKTSDISTL
GHLVITTQGGYVKILDLSNFEILAKVEPPKKEGTEEQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEPSSEGSKPLSNPSSPGISGVDLLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQ
QEQQQRRHPQHLHQQHHGDAAQHTRTWKLQTDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITNIPQIQVTLLKNKAPGLGKVNALNIEVEQNGKPSLVDLNEEMQHMDVEESQCLRLCPFLEDHKEDILCGPVWLASGLDLSGHAGM
LTLTSPKLVKGMAGGKYRSFLIHVKAVNERGTEEICNGGMRPVVRLPSLKHQSNKGYSLASLLAKVAAGKEKSSNVKNENTSGTRKSENLRGCDLLQEVSVTIRRFKKTSISKERVQRCAMLQFSEFHEKLVNTLCRKTDDGQITEHAQS
LVLDTLCWLAGVHSNGPGSSKEGNENLLSKTRKFLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCDPCQPAFGPVLLKALLDNMSFLPAATTGGSVYWYFVLLNYVKDEDLAGCSTACASLLTAVSRQLQDRLTPMEALLQTRYGLYS
SPFDPVLFDLEMSGSSCKNVYNSSIGVQSDEIDLSDVLSDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEE
TCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQVRTLKLILSTQGGSCTEQK


check button N-Truncated Protein (5UTR-3CDS) Sequences

check button C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for BIRC6_TTC27


check button TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences
NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button TCGA All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

check button CCLE All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

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Fusion Gene Exprssed Samples for BIRC6_TTC27


check buttonRNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDBACCTCGA-OR-A5JC-01ABIRC6

chr2

32582554+TTC27

chr2

32582554

+
ChimerDBACCTCGA-OR-A5JCBIRC6

chr2

32582554+TTC27

chr2

32582554

+
ChimerDBBRCATCGA-AR-A256-01ABIRC6

chr2

32774548+TTC27

chr2

32774548

+
ChimerDBBRCATCGA-BH-A18J-01ABIRC6

chr2

32605358+TTC27

chr2

32605358

+
ChimerDBESCATCGA-2H-A9GHBIRC6

chr2

32774548+TTC27

chr2

32774548

+
ChimerDBESCATCGA-LN-A49U-01ABIRC6

chr2

32695369+TTC27

chr2

33002948

+
ChimerDBESCATCGA-LN-A49UBIRC6

chr2

32695369+TTC27

chr2

32695369

+
ChimerDBOVTCGA-09-2054-01ABIRC6

chr2

32704685+TTC27

chr2

32704685

+
ChimerDBSTADTCGA-D7-A4YU-01ABIRC6

chr2

32768608+TTC27

chr2

32768608

+
ChimerDBSTADTCGA-D7-A4YUBIRC6

chr2

32768608+TTC27

chr2

32768608

+
ChimerDBUCSTCGA-N9-A4Q4BIRC6

chr2

32582554+TTC27

chr2

32582554

+
cBioPortalCCLE_GENENTECH_2014MIXEDS-LS1034BIRC6

chr2

32836649TTC27

chr2

33036091


check buttonDNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrandSV type
dbVarestd214Unknown_CellHG00275BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd214Unknown_CellHG01344BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd214Unknown_CellHG03082BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd214Unknown_CellHG00275BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd214Unknown_CellHG03082BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd214Unknown_CellNA18628BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd214Unknown_CellNA20847BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd219Unknown_CellHG00275BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd219Unknown_CellHG01344BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd219Unknown_CellHG03082BIRC6

chr2

32673976TTC27

chr2

32965429

DUP
dbVarestd219Unknown_CellHG00275BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd219Unknown_CellHG03082BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd219Unknown_CellNA18628BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd219Unknown_CellNA20847BIRC6

chr2

32838747TTC27

chr2

32948602

DUP
dbVarestd221Whole bloodC010130BIRC6

chr2

32633690TTC27

chr2

32961858

DUP
dbVarestd224Unknown_CellBIRC6

chr2

32769351TTC27

chr2

32883197

DUP
dbVarnstd100Unknown_CellUnknown_Set_9895376BIRC6

chr2

32686961TTC27

chr2

32988840

DEL
dbVarnstd100Unknown_CellBIRC6

chr2

32765390TTC27

chr2

32902085

DUP
dbVarnstd100Unknown_CellBIRC6

chr2

32768661TTC27

chr2

32915357

DUP
dbVarnstd100Unknown_CellUnknown_Set_9879609BIRC6

chr2

32779552TTC27

chr2

32945650

DUP
dbVarnstd102Unknown_CellBIRC6

chr2

32624578TTC27

chr2

32915356

DEL
dbVarnstd102Unknown_CellBIRC6

chr2

32703576TTC27

chr2

32971021

DEL
dbVarnstd102Unknown_CellBIRC6

chr2

32746129TTC27

chr2

32913607

DEL
dbVarnstd102Unknown_CellBIRC6

chr2

32787199TTC27

chr2

32968519

DUP
dbVarnstd112Genomic/Cell_LineHGDP01414BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01417BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01028BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01035BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01030BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01034BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00457BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00461BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineDNK11BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineDNK5BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG02943BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHG03100BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHG02464BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG02574BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineSA0722BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112GenomicNA19023BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112GenomicNA19044BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112GenomicAyodo502CBIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00915BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01199BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA21490BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00449BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00476BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG03078BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG03085BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01253BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01274BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineSAH31BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00987BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00991BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01032BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineAyodo81SBIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00928BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00932BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00474BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellTGBS21BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01012BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01018BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00855BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00857BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_Linemixe0002BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_Linemixe0042BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineMixa0099BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_Linemixa0105BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00702BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00706BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01044BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHGDP01047BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA11201BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LinePeru60BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00846BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00852BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_Linezapo0098BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellDNSBIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellNDLBIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellNA13607BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA13616BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA13604BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineBu5BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00713BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00717BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01312BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01314BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01315BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01215BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00783BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00785BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01240BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01242BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00749BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00773BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA18940BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG01600BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG01846BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA00726BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineND19394BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01320BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01323BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01191BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01198BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01223BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01228BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01338BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01344BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01345BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01203BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01211BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01333BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineCHI-007BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineCHI-034BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01350BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01355BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01095BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01098BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01297BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01306BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01246BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01250BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01179BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01188BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineIHW9118BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellIHW9193BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00656BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellDus16BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA17385BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineIgor21BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA17386BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00540BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00541BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00543BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00545BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00547BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00548BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00549BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00550BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00551BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00552BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00553BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00554BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00555BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00556BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00090BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG03006BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG03007BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00019BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00027BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00338BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00428BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00124BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00125BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHGDP00286BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHGDP00328BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellK-15BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineK-2BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineM13BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00157BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00160BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00216BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG02724BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHG02783BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHG02790BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHGDP00195BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellHGDP00208BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodAle20BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodAle22BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodSir19BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodSir26BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodEsk29BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodNesk22BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodNesk25BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodSir40BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellNlk18BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodNlk1BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodNlk3BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodKor82BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodMansi79BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodMansi41BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodAle14BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112BloodAle32BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodTuba19BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodTuba9BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodUl31BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/BloodUl5BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00951BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00956BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellabh100BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellabh107BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01401BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01402BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellaltai363pBIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellarmenia293BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01364BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01365BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00616BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00650BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01153BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01172BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellBulgarianB4BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellBulgarianC1BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellch113BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA15728BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00569BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00597BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG00126BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG00128BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellEst375BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellEst400BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG00174BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG00190BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG00360BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00526BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00530BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Cellmg31BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA17374BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA17377BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA15202BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA15203BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA15761BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineNA15763BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Celliran11BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Celliran17BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellUnknown_Set_1771BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellUnknown_Set_4291BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellJordan603BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Celllez42BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_Celllez49BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellNOR111BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00796BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00798BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00722BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00725BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00737BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineND15865BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00887BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP00903BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellUtsa21BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01078BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01079BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG01503BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHG01504BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01163BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Genomic/Cell_LineHGDP01168BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellUnknown_Set_4695BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd112Unknown_CellUnknown_Set_5433BIRC6

chr2

32738045TTC27

chr2

32899566

DUP
dbVarnstd113Unknown_CellUnknown_Set_25905BIRC6

chr2

32686961TTC27

chr2

32988840

DEL
dbVarnstd113Unknown_CellUnknown_Set_41672BIRC6

chr2

32779552TTC27

chr2

32945650

DUP
dbVarnstd122Unknown_CellBIRC6

chr2

32832260TTC27

chr2

33034057

DUP
dbVarnstd145Unknown_Cellsample410BIRC6

chr2

32781405TTC27

chr2

32916076

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32654212TTC27

chr2

32927992

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32664574TTC27

chr2

33042629

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32664574TTC27

chr2

32961888

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32688260TTC27

chr2

32875305

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32688260TTC27

chr2

32875305

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32692591TTC27

chr2

32983591

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32818980TTC27

chr2

32927992

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32822816TTC27

chr2

33012221

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32842790TTC27

chr2

33012221

DUP
dbVarnstd151Unknown_CellBIRC6

chr2

32842790TTC27

chr2

33042629

DUP
dbVarnstd166Unknown_CellBIRC6

chr2

32782999TTC27

chr2

32957000

DUP
dbVarnstd173Unknown_Cell232712SBIRC6

chr2

32716012TTC27

chr2

32968823

DEL
dbVarnstd174Unknown_CellBIRC6

chr2

32838747TTC27

chr2

33042517

DUP
dbVarnstd183Unknown_CellBIRC6

chr2

32769506TTC27

chr2

32874181

DUP
dbVarnstd183Unknown_CellBIRC6

chr2

32843419TTC27

chr2

33020535

DUP
dbVarnstd189Unknown_CellBIRC6

chr2

32699800TTC27

chr2

33023757

DUP
dbVarnstd200Unknown_CellBIRC6

chr2

32738300TTC27

chr2

32896058

DUP
dbVarnstd200Unknown_CellBIRC6

chr2

32811944TTC27

chr2

33045164

DUP
dbVarnstd200Unknown_CellBIRC6

chr2

32841911TTC27

chr2

33045355

DUP
dbVarnstd200Unknown_CellBIRC6

chr2

32841911TTC27

chr2

33045355

DUP
dbVarnstd204Unknown_CellBIRC6

chr2

32811944TTC27

chr2

33045164

DUP
dbVarnstd209Unknown_CellBIRC6

chr2

32738300TTC27

chr2

32896055

DUP
dbVarnstd223Unknown_CellBIRC6

chr2

32739147TTC27

chr2

32872692

DUP
dbVarnstd223Unknown_CellBIRC6

chr2

32767651TTC27

chr2

32930348

DUP
dbVarnstd223Unknown_CellBIRC6

chr2

32841911TTC27

chr2

33045355

DUP
dbVarnstd224salivaOSC2215BIRC6

chr2

32688454TTC27

chr2

32875274

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32645184TTC27

chr2

32934001

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32767651TTC27

chr2

32930348

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32777703TTC27

chr2

32971895

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32807608TTC27

chr2

32995486

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32828468TTC27

chr2

32931967

DUP
dbVarnstd229Unknown_CellBIRC6

chr2

32841911TTC27

chr2

33045355

DUP
dbVarnstd239Unknown_Cell200162510070_R02C02BIRC6

chr2

32621143TTC27

chr2

32969116

DUP
dbVarnstd239Unknown_Cell200162510070_R02C02BIRC6

chr2

32621143TTC27

chr2

32969116

DUP
dbVarnstd239Unknown_CellWG1004358-DNAF07-010886-0095502304BIRC6

chr2

32633569TTC27

chr2

32960091

DUP
dbVarnstd239Unknown_CellWG1004380-DNAF09-011638-0095500477BIRC6

chr2

32633569TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200162510001_R02C02BIRC6

chr2

32633569TTC27

chr2

33039690

DUP
dbVarnstd239Unknown_Cell200162510005_R06C02BIRC6

chr2

32633569TTC27

chr2

33013822

DUP
dbVarnstd239Unknown_Cell200162510005_R06C02BIRC6

chr2

32633569TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200162510034_R08C01BIRC6

chr2

32633569TTC27

chr2

32904596

DUP
dbVarnstd239Unknown_Cell200162510141_R09C01BIRC6

chr2

32633569TTC27

chr2

32904596

DUP
dbVarnstd239Unknown_Cell200162510151_R07C02BIRC6

chr2

32633569TTC27

chr2

33013822

DUP
dbVarnstd239Unknown_Cell200162520033_R11C02BIRC6

chr2

32633569TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200085980061_R05C01BIRC6

chr2

32654636TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200085980061_R05C01BIRC6

chr2

32654636TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200162520046_R07C02BIRC6

chr2

32654636TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_Cell200162520046_R07C02BIRC6

chr2

32654636TTC27

chr2

32933095

DUP
dbVarnstd239Unknown_CellWG1004387-DNAG09-016877-0095502845BIRC6

chr2

32661543TTC27

chr2

32940834

DUP
dbVarnstd239Unknown_CellWG1004387-DNAG09-016877-0095502845BIRC6

chr2

32661543TTC27

chr2

32918720

DUP
dbVarnstd239Unknown_CellWG1004387-DNAG09-016877-0095502845BIRC6

chr2

32661543TTC27

chr2

32918720

DUP
dbVarnstd239Unknown_CellWG1004344-DNAB09-014526-0095502712BIRC6

chr2

32666137TTC27

chr2

32879162

DUP
dbVarnstd239Unknown_CellWG1004344-DNAB09-014526-0095502712BIRC6

chr2

32679732TTC27

chr2

32861950

DUP
dbVarnstd239Unknown_CellWG1006264-DNAG08-021939-1047868769BIRC6

chr2

32691438TTC27

chr2

32881819

DUP
dbVarnstd239Unknown_CellWG1006264-DNAG08-021939-1047868769BIRC6

chr2

32691438TTC27

chr2

32881819

DUP
dbVarnstd239Unknown_CellWG1006264-DNAG08-021939-1047868769BIRC6

chr2

32691438TTC27

chr2

32881819

DUP
dbVarnstd239Unknown_CellWG1004319-DNAC08-013191-0095478266BIRC6

chr2

32735881TTC27

chr2

32861950

DUP
dbVarnstd239Unknown_CellWG1004319-DNAC08-013191-0095478266BIRC6

chr2

32735881TTC27

chr2

32861950

DUP
dbVarnstd239Unknown_CellUnknown_Set_18167BIRC6

chr2

32744989TTC27

chr2

32875069

DUP
dbVarnstd239Unknown_Cell200162460097_R05C02BIRC6

chr2

32806385TTC27

chr2

32977741

DUP
dbVarnstd239Unknown_Cell200162460097_R05C02BIRC6

chr2

32806385TTC27

chr2

32969116

DUP
dbVarnstd239Unknown_Cell200162460097_R05C02BIRC6

chr2

32806385TTC27

chr2

32977741

DUP
dbVarnstd27Unknown_CellHGDP00548BIRC6

chr2

32754986TTC27

chr2

32897055

DUP
dbVarnstd30B-lymphocytesHGDP00548BIRC6

chr2

32754986TTC27

chr2

32883196

DUP
dbVarnstd54Unknown_CellBIRC6

chr2

32633690TTC27

chr2

32918112

DUP
dbVarnstd54Unknown_CellUnknown_Set_9895376BIRC6

chr2

32686961TTC27

chr2

32988840

DEL
dbVarnstd54Unknown_CellHGDP00548BIRC6

chr2

32754986TTC27

chr2

32897055

DUP
dbVarnstd68Unknown_CellBIRC6

chr2

32678414TTC27

chr2

32853192

DEL
dbVarnstd68Unknown_CellBIRC6

chr2

32820054TTC27

chr2

32999091

DEL
dbVarnstd71Unknown_CellSP55878BIRC6

chr2

32755109TTC27

chr2

32897055

DEL
dbVarnstd71Unknown_CellIS35499BIRC6

chr2

32782763TTC27

chr2

32961858

DUP
dbVarnstd71Unknown_CellMS18263BIRC6

chr2

32810293TTC27

chr2

32924202

DUP
dbVarnstd86Unknown_CellBIRC6

chr2

32836649TTC27

chr2

33036089

DUP


Top

Related Drugs for BIRC6_TTC27


check button PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.
PMIDFusion Gene NameDrugStudy Title

check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status