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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:SHROOM4_ARID3A (FusionGDB2 ID:HG57477TG1820)

Fusion Gene Summary for SHROOM4_ARID3A

Fusion gene summary

Fusion gene information	Fusion gene name: SHROOM4_ARID3A
	Fusion gene ID: hg57477tg1820
		Hgene	Tgene
	Gene symbol	SHROOM4	ARID3A
	Gene ID	57477	1820
	Gene name	shroom family member 4	AT-rich interaction domain 3A
	Synonyms	MRXSSDS\|SHAP\|shrm4	BRIGHT\|DRIL1\|DRIL3\|E2FBP1
	Cytomap	Xp11.22	19p13.3
	Type of gene	protein-coding	protein-coding
	Description	protein Shroom4second homolog of apical protein	AT-rich interactive domain-containing protein 3AARID domain-containing 3AARID domain-containing protein 3AAT rich interactive domain 3A (BRIGHT- like) proteinAT rich interactive domain 3A (BRIGHT-like)B-cell regulator of IgH transcriptionE2F-binding
	Modification date	20240305	20240305
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000289292, ENST00000376020, ENST00000460112, ENST00000483955,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 6 X 7 X 8=336	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 6 X 15 X 12=1080
	# samples	11	30
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(11/33610)=-1.6109577092541 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(30/108010)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SHROOM4 [Title/Abstract] AND ARID3A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	SHROOM4(50556901)-ARID3A(960091), # samples:1

Fusion gene breakpoints across SHROOM4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ARID3A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for SHROOM4_ARID3A

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
SHROOM4	chrX	50556901	ARID3A	chr19	50556901
SHROOM4	chrX	50556901	ARID3A	chr19	960091
SHROOM4	chrX	50556902	ARID3A	chr19	960092
SHROOM4	chrX	50813902	ARID3A	chr19	960092

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for SHROOM4_ARID3A

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
SHROOM4-ARID3A	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity M2		SHROOM4 cytoskeletal protein couples to ARID3A transcription factor, coordinating cytoskeletal stroma with aberrant developmental transactivation.		Transcriptional CDK inhibitors; cytoskeletal modulators		Carcinomas and solid tumors

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
SHROOM4-ARID3A	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity M2	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 38781729; Title: ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis.	SHROOM4 cytoskeletal protein couples to ARID3A transcription factor, coordinating cytoskeletal stroma with aberrant developmental transactivation.		Transcriptional CDK inhibitors; cytoskeletal modulators		Carcinomas and solid tumors	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 38781729; Title: ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis.; PMID: 40181152; Title: Phosphorylation enhanced OTUD3 deubiquitination ARID3A promotes the progress of cholangiocarcinoma.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	SHROOM4	GO:0000902	cell morphogenesis	16684770
Hgene	SHROOM4	GO:0007420	brain development	16249884
Hgene	SHROOM4	GO:0050890	cognition	16249884

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Fusion Genomic Features for SHROOM4_ARID3A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
SHROOM4	chrX	50556901	-	ARID3A	chr19	960091	+	1.26e-05	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for SHROOM4_ARID3A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000289292	ENST00000263620	SHROOM4	chrX	50556901	-	ARID3A	chr19	960091	+
In-frame	ENST00000376020	ENST00000263620	SHROOM4	chrX	50556901	-	ARID3A	chr19	960091	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000289292	ENST00000263620	SHROOM4	chrX	50556901	ARID3A	chr19	960091	401	401
ENST00000376020	ENST00000263620	SHROOM4	chrX	50556901	ARID3A	chr19	960091	143	2177

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000289292	ENST00000263620	SHROOM4	chrX	50556901	ARID3A	chr19	960091	5.92e-03	9.94e-01
ENST00000376020	ENST00000263620	SHROOM4	chrX	50556901	ARID3A	chr19	960091	6.67e-03	9.93e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for SHROOM4_ARID3A

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

SHROOM4_ARID3A_chrX-50556901_chr19-960091.png

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

549_576

231.0

594.0

Compositional bias

Gly residues

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

580_593

231.0

594.0

Compositional bias

Low complexity

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

238_330

231.0

594.0

Domain

ARID

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

444_541

231.0

594.0

Domain

REKLES

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

445_488

231.0

594.0

Region

Important for nuclear localization

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

490_513

231.0

594.0

Region

Note=Homodimerization

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

497_516

231.0

594.0

Region

Disordered

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

537_557

231.0

594.0

Region

Important for cytoplasmic localization

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

539_593

231.0

594.0

Region

Disordered

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1382_1488

39.0

1898.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1118_1129

39.0

1898.0

Compositional bias

Low complexity

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1132_1159

39.0

1898.0

Compositional bias

Acidic residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

234_243

39.0

1898.0

Compositional bias

Polar residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

249_262

39.0

1898.0

Compositional bias

Polar residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

470_484

39.0

1898.0

Compositional bias

Basic and acidic residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

498_509

39.0

1898.0

Compositional bias

Basic and acidic residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

513_547

39.0

1898.0

Compositional bias

Polar residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

782_802

39.0

1898.0

Compositional bias

Polar residues

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

10_92

39.0

1898.0

Domain

PDZ

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1213_1492

39.0

1898.0

Domain

ASD2

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1117_1170

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1187_1206

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1214_1236

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

1246_1265

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

202_282

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

430_695

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

740_759

39.0

1898.0

Region

Disordered

Hgene

SHROOM4

chrX:50556901

chr19:960091

ENST00000289292

Q9ULL8

781_813

39.0

1898.0

Region

Disordered

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

104_127

231.0

594.0

Compositional bias

Basic and acidic residues

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

128_158

231.0

594.0

Compositional bias

Acidic residues

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

41_53

231.0

594.0

Compositional bias

Basic and acidic residues

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

54_87

231.0

594.0

Compositional bias

Low complexity

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

119_156

231.0

594.0

Region

Note=Acidic

Tgene

ARID3A

chrX:50556901

chr19:960091

ENST00000263620

Q99856

14_222

231.0

594.0

Region

Disordered

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for SHROOM4_ARID3A

In-frame Fusion Transcript Sequences.

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091 length=5364nt 
 Breakpoint=401nt
CCGTTTTCTTGTCCATTACGCGCTATCCCTCCGCCTCTCCTTCTTTCTTTTCTTTTCTTTTTTTCCCTTCTCCTTTTCCCCCCTCTCTCCCCCTTTCTCCAGCTCCGTGTCATTTCCTCCTTGCGCTCGCTCGCTGCCTGAGCGTCTCCA
GCCGGGAGAGTAGGCGGAGCAGGGCGGTGCGGGGTGGCGTAGAGCTGGAGGGCGATGGTGGCGGAGCTGCTGGGGGCGGAGGCAACGTAGCCCCCTCGGAAAAGGAGCCCGGCGGCGCCTGAGCCCAGCCGAGGATGGAGAACCGGCCTG
GGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGGGCTTCACCCTTAAGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACGAACTCGACGGGGACCCCAAGAGGAAGGAATTCCTGGATGACT
TGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCATGCTGTACGTGCTGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCA
CCAAGGGCCTCAACCTGCCCACGTCCATCACCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTAACCCCAATGAGCTCCAGGCAGCCATAGACAGCAACCGACGGG
AGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAGGCGGGGCACACGGCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCGCCCCTAAGATCA
AGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGGCAGCCCAGGCAGCAGCTGTGCAAGCAGCAGCCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAAC
AGCTGCGGGAGAAGCTGGAGTCTGCAGAGCCTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGGCCATGGCGGCCCAGCTGCCCATGAGCATTCGGATCAACAGCC
AAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCAACGGCAGCAACAGCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTCTGTTTGCTCAGCCGCCGGCCCCCACGCCAACCTCTGCTCCCA
ACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCCAGGCTGGGCCAGCGGGGCTGTCCACACCCTCCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACT
CCCCACCCGCCACCCACCCTGGAGCCCGCCGGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAGAAAGGAGCCACAGCTGACGCCAAAAAGAAAAGAAAAAAGATA
TATATATATATATATATATATACACGTATATATATAAAGAGAATTTAATAAAACAGGGGAAAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGATGAATTGTGAGAACAGCAAAGAAATCCATCAGAAAAACAGAAA
GAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGTGTGGGCCGATCCTGTTTACCTCATACATCCCTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTT
TATTTTCTATTCACCACACACTCACCACTCCCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTTTTTTTTCTCTGTAGGGTTTTTAAGAGGTTTCGGGGGTTTTGT
TGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAAGGATATCTATATATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAAAAAGCAAGAAAAAAAAGCAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGTGAGCCCAGCACATCGGATCCCTGGGGCTAGAGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGG
GGCAGAGGGTGCATGCTGGGGTCCCACCGGCCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCTCTCGAGTCAGGGGCCTGGAAATTTTTTTTTTTTTTTTTTTTT
GAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGTGCGATCTTGGCTCACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCAG
TTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATC
TTATCTAAAAAGTAGCAAGTGCTGGAAAAAGGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGATTCTTCTCTTGCCCGAAAGGGCTGCTTTTGAGGACTATCAAT
ACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCAGGGCCCCGGCATCCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCTCTTCTCCCAACCCCTTTTGTGCTGGGGCTGCGAGCTCCCCGA
GTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGCTTGGAGAAAGTGGGGTCACCGCAGCTGAGCTGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTG
GGTCTGAAATGCCCAGCAGGGTCTGGGGACTTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTGCAGTGGGGATTAACTCAGCTATTCCCAGGGTAAGCCTGGGTC
TCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTGGTGAGGAAGGGGACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGACCCCTGGGGAGGGGGCTGGGGGGCTTCTGAGCCCCTGAGTCT
AGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTCTCGGATCTCAGGGCCGTGGACACACACCCCCTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCC
CTTCCTGGGGCCAGCACCGTAGCAGCACAATCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGTGTCTGTCCCCCGGCCTCCAGGGCTCCTCTCCCGGGACCCCCG
TCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCTGTCTACCTCAGGTCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCGCCTCCCGTGCACCAGGGTCTGCAGCAGCCACTGGGGCCTGGC
TGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTGCAGGGTCGAGGGCTGGGTCGTCTCCCTCGGGCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGG
GCGATCCGGCCTCCCGGCGGTGGGTGGACCTGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGGCGCGAGGCTGGGTCCCGGCCCAGGAGAAGGAAGTCGCTGAAG
GCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCTATGGGGCCCGGTCCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCTCAGGTGGCCCCGTTCAACCCCAGCCGTGCCCATCTCCTGCCA
CCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAGGGGGTCGGGCAGTCCCCTCAGCCACGAGGACCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGC
TGCGTACTGAGTGGGTGCCCCACAGTCAAGGCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGCTGTCCAGAAAGGCGGGAGGGTGGGCACGGGGCACGGGGGGCA
GCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTTTCTCTTATCATGTTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTTTTCCTTGGCAAATGTAAACTCAGCCTTTCATTCATGACGTGT
GAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAAAAAACTTAAAAAAATTTTTAAAAAACATAAAACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCT
GGCCGCGGCAGGGTGGCCTGTAACAATTTCAGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGATTTTGAAATTTAAAAGAACACTGAAAGTTTACATTTTATAGT
AACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGATTGTAACCCTGTAAAGCTGATGAGATATTAAAACGAGACAAAACACTTCTGACTTTTAACAGAAAA

>SHROOM4_ARID3A_ENST00000376020_ENST00000263620_50556901_960091 length=5106nt 
 Breakpoint=143nt
CCGGCGGCGCCTGAGCCCAGCCGAGGATGGAGAACCGGCCTGGGTCCTTCCAGTACGTCCCTGTGCAGCTGCAAGGGGGGGCACCCTGGGGCTTCACCCTTAAGGGGGGTCTGGAACACTGTGAGCCGCTCACAGTGTCTAAGCTCTACG
AACTCGACGGGGACCCCAAGAGGAAGGAATTCCTGGATGACTTGTTCAGCTTCATGCAGAAGCGAGGGACACCTGTGAACCGCATCCCCATCATGGCCAAACAGGTCCTTGACCTGTTCATGCTGTACGTGCTGGTGACGGAGAAGGGCG
GCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGCCCACGTCCATCACCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTA
ACCCCAATGAGCTCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAGGCGGGGCACACGGCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCG
CAAGCACCAATGGCAGCTCCATCACCCCCGCCCCTAAGATCAAGAAAGAGGAGGACTCAGCCATCCCCATCACAGTCCCTGGCCGCCTGCCTGTGTCCCTGGCGGGCCACCCTGTGGTGGCAGCCCAGGCAGCAGCTGTGCAAGCAGCAG
CCGCCCAAGCAGCTGTGGCCGCACAGGCAGCTGCCCTGGAACAGCTGCGGGAGAAGCTGGAGTCTGCAGAGCCTCCGGAGAAGAAGATGGCCCTGGTGGCCGATGAGCAGCAACGGCTGATGCAACGTGCACTCCAGCAGAACTTCCTGG
CCATGGCGGCCCAGCTGCCCATGAGCATTCGGATCAACAGCCAAGCCTCCGAAAGCCGCCAGGACTCTGCTGTGAACCTGACGGGCACCAACGGCAGCAACAGCATCAGCATGTCGGTGGAGATCAACGGCATCATGTACACAGGAGTTC
TGTTTGCTCAGCCGCCGGCCCCCACGCCAACCTCTGCTCCCAACAAAGGAGGCGGCGGCGGCGGCGGCAGCAGCAGCAACGCAGGCGGCCGGGGAGGAAACACCGGAACCAGCGGCGGCCAGGCTGGGCCAGCGGGGCTGTCCACACCCT
CCACATCTACCTCAAATAACTCGTTGCCTTAACCGCATCACTCCCCACCCGCCACCCACCCTGGAGCCCGCCGGCCTGGGCAGGGGGTCCAGGTGGGCCACACAGGGGCCAGGATGGCGGAAGATACGGGTGGGGAGGGAAGATATCCAG
AAAGGAGCCACAGCTGACGCCAAAAAGAAAAGAAAAAAGATATATATATATATATATATATATACACGTATATATATAAAGAGAATTTAATAAAACAGGGGAAAACCAAGGAACACTTGAATTTCTCAGGTTTTGGACATTCAGAGAGAT
GAATTGTGAGAACAGCAAAGAAATCCATCAGAAAAACAGAAAGAGGCAGACGTTTCCCAGGGCGTTCAGGCAGCCCTGATGGACCGAAGGCTCTGGTGTCTGGTTTGGCCCCACAGCAGTGTGGGCCGATCCTGTTTACCTCATACATCC
CTGCACTGTGTGTTTTCATTTTTGTCTGCTTTAGTTCTCTTTTATTTTCTATTCACCACACACTCACCACTCCCAGCTTCTCGTGTCCAGTGAAACCCCTGAACCAAGATCACTGAATTTTTGTTTTTTTCTTGTTGCTTTGGGAAATTT
TTTTTTCTCTGTAGGGTTTTTAAGAGGTTTCGGGGGTTTTGTTGTGTAAATATTCTATTTTATTCTTGGGGGGATCAAACCTTAGGAAAAGGATATCTATATATCTATATAGCTATATATTTGTGTTCCTTCAGGGAAACTGGTCTTGAA
AAAGCAAGAAAAAAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCACCTTTTTATTTTTCCCATGACCAATTTGGGTCCCTTTGTCCATTTCTGGGGGTGCGTTGGGCAGCTGTGAGCCCAGCACATCGGATCCCTGGGGCTAG
AGCCGCGGAGCCAATGAACTCAGGTGCTATGGGCCGGGCTGGGGCAGAGGGTGCATGCTGGGGTCCCACCGGCCAGGGGCCCCTGACAGTGAATTGCTGACTGTGATATTCCACGATGCTTTTGCTTGTGCCGTGCTTGTCTGCTGGGCT
CTCGAGTCAGGGGCCTGGAAATTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCGCCCAGGCTGGAGTGAGTGCAATGGTGCGATCTTGGCTCACTGCAACCTGCACCTCCCAGGTGCAAGCGATTCTCCTGCCTCAGCC
TCCGGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCAGTTAATTTTTGTATTTTTAGTAGAGATGGGGGTTTTGCCATGTTGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGG
GATTACAGGCATGAGCCGCCACGCTGGCCCGGTCTGGAAATCTTATCTAAAAAGTAGCAAGTGCTGGAAAAAGGGCCTGGGGGGCGGGGGTGGTTCTTGTCGAAGCCCCCAGGCTCCTGTCTCAGGGATGAATGTGGCGTCTCATTGGGA
TTCTTCTCTTGCCCGAAAGGGCTGCTTTTGAGGACTATCAATACTGGGGAGTGGGGGTGAAGCCGGACCTCACTCAGGGTGAGGATTTCAGGGCCCCGGCATCCTGAACACCCCCCACACCCCAACATTCTCCTCGCTCTGTCCCTTCCT
CTTCTCCCAACCCCTTTTGTGCTGGGGCTGCGAGCTCCCCGAGTTCTGCGGTGACTAAATCGAGGCCGAGAAGGGAGGCTGCCCCCCACCACCCTGTGGGTCAGTACCCCTCCCCCTGGCTTGGAGAAAGTGGGGTCACCGCAGCTGAGC
TGGGGGGTTATTTTGGCTGGAGCTGCTGGAGCAGAAAGGCTGGGTCTGAAATGCCCAGCAGGGTCTGGGGACTTCGTTGGACCCGCGTGGTGTTGGGCGGGGCTGTCGTGTCCTACACGGGAGCTCTGGGCTTTCATTTCTCTTGGGGTG
CAGTGGGGATTAACTCAGCTATTCCCAGGGTAAGCCTGGGTCTCTAATTGGGCCCTGGGAGCCCTGTTAGGCCACCGGCATGGGGGCTTGGTGAGGAAGGGGACTCCCCAGCTCCCCCCACTCCCAACCACCTCCCCATTGCCTTGGAGA
CCCCTGGGGAGGGGGCTGGGGGGCTTCTGAGCCCCTGAGTCTAGGTTCACTTTCCCGTCGGGCTGTGGGAGGGGACTGTCACTTTCCTGTGTCTTTGGGGAGGGGACCCCCACTTCCTTCTCGGATCTCAGGGCCGTGGACACACACCCC
CTTTCCAGGAGGGGGTGGTGGGCGTCTAGGTTTTCCTTGTCCCTTCCTGGGGCCAGCACCGTAGCAGCACAATCACCCCGGGAAGGGGGTGTCTGTTTGCCTCCAGACACAATCGGGCCCCACTCGCAGAACCACCTGGACTCTGTCCGT
GTCTGTCCCCCGGCCTCCAGGGCTCCTCTCCCGGGACCCCCGTCCCACGCCTGGGCCCCGCGCCGGGGGAAGCGCCTGCTGCCTATCTCTGTCTACCTCAGGTCTGACTTTTGATGCCAAAATCTGAGCCCCTGGGGTGCCTCTCCCCCG
CCTCCCGTGCACCAGGGTCTGCAGCAGCCACTGGGGCCTGGCTGCCTGCTGCATCTGGCGGCCCTGGACCCCTGGGGCCCCCGTGCACCTGCCCACCTCGGAGCCTGGGGAGGGGCCGTGCAGGGTCGAGGGCTGGGTCGTCTCCCTCGG
GCTGCGTGTGTGTGTCGGGAATCCTGCGTGTCGTGTCTGTGGGCGATCCGGCCTCCCGGCGGTGGGTGGACCTGGATTCTAACTCAGAGGACTTGAGCCTGCTGTTAACTCCGATGATTGTAGGGACAGGCGGGGTGGGTGGGGGGTGGG
CGCGAGGCTGGGTCCCGGCCCAGGAGAAGGAAGTCGCTGAAGGCAGTGGCCATGCTGGCCGTGGAAATGGGAGGCGGTTGCAGAGGGTCTATGGGGCCCGGTCCTGGATACTCGGCAGGAAGCCGTGTCTGCAGAGGCTCCTCCCTGCCT
CAGGTGGCCCCGTTCAACCCCAGCCGTGCCCATCTCCTGCCACCGCCTGTCGGTGGGGGTTTAAATTCGGTGTGGCTTTCTGGGGTGCAGCTCAGCACCCCCCCTTATGCAGACTGGGAGGGGGTCGGGCAGTCCCCTCAGCCACGAGGA
CCCTGGATGGGTTCTAGTTCACTTGGGACCGTGGGGCCTGGCTGCGTACTGAGTGGGTGCCCCACAGTCAAGGCCAACGGGGGCTCCCCCTGCTCTGAGATGTTGGGAGAAAGGCGGCTTCTGGAACCTTCCGTGGGACCCGTAAGTGGC
TGTCCAGAAAGGCGGGAGGGTGGGCACGGGGCACGGGGGGCAGCTGGGGTCGTTGTTAAGGGTCACGCATCTGTACAGTTGAATTTCCTTTCTCTTATCATGTTTTACCCACCTTGTCCCTTTTTTCCCCAATTGTGCTTTTGCATTTTT
TTCCTTGGCAAATGTAAACTCAGCCTTTCATTCATGACGTGTGAAATTTCAGTTTCTCTGGAGTTTGTCAGACGGCGTGGGAACCACGCCTGAAACTCAGGTAATAGGAGGAAAAAAAAAAAAACTTAAAAAAATTTTTAAAAAACATAA
AACTACTCTCTACCTCTGGCTGGGCCCAGCCTGTCTCGCCCTGGCCGCGGCAGGGTGGCCTGTAACAATTTCAGTTTTCGCAGAACATTCAGGTATTAAAAGGAAAAAAAAAAAAAAAGACAAAAAGACCAAAAAAAAAAAAAAGTGTGA
TTTTGAAATTTAAAAGAACACTGAAAGTTTACATTTTATAGTAACATTATTATGCAGATTGTATTTAAACTTCAGAAATATTTAAGACGATTGTAACCCTGTAAAGCTGATGAGATATTAAAACGAGACAAAACACTTCTGACTTTTAAC
AGAAAA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

Top

Fusion Protein Sequence for SHROOM4_ARID3A

In-frame Fusion Protein Sequences.

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091 length=401nt
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000376020_ENST00000263620_50556901_960091 length=2177nt
MRDHVFGMMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSG
GVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARG
GLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENS
PPVKPKHNYTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLSPVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHS
NKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDFQEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQVSYPRPEGRTGASASFNSTDPSPE
EPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHNYRPHRTVSTSSTSGNDFEETKAHIRFSESAEPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQ
LSSEPEREPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQ
RNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGAN
GGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLV
TDTRAAPLTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESV
LRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSVHAQLAGSLGGQPAPIQTQSLSHD
PVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKEAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHK
LETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRSLDWWITDKCNMINGT
DGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDI
RTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for SHROOM4_ARID3A

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.R450W_401_R258W length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLWEKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.M529I_401_M337I length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIIYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.L245V_401_L53V length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFVDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.N514I_401_N322I length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTIGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.A578V_401_A386V length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPVGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.S557G_401_S365G length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGGSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G563S_401_G371S length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGSRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.I289M_401_I97M length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVMNKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.L322M_401_L130M length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYMYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.R330W_401_R138W length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKWGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G365R_401_G173R length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGRAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.A536V_401_A344V length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFVQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.L245M_401_L53M length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFMDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.S557G_401_S365G length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGGSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G365R_401_G173R length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGRAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G237W_401_G45W length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDWDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G554R_401_G362R length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGRGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.S557G_401_S365G length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGGSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.A394T_401_A202T length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPTPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G365V_401_G173V length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGVAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.L270I_401_L78I length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVIDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.E524K_401_E332K length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVKINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.R412L_401_R220L length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGLLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G555S_401_G363S length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGSGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.P547S_401_P355S length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSASNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.S333N_401_S141N length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLNNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G237W_401_G45W length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDWDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.P547L_401_P355L length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSALNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G555S_401_G363S length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGSGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.A456V_401_A264V length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESVEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.V523A_401_V331A length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSAEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.P263H_401_P71H length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIHIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.P410H_401_P218H length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVHGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G283D_401_G91D length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKDGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.R261H_401_R69H length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNHIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.G555S;p.S557G_401_G363S;S365G length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGSGGSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.P458T_401_P266T length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAETPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.L278M_401_L86M length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVMVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.N548K_401_N356K length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPKKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.T316S_401_T124S length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRSQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.M491I_401_M299I length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPIS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.V277M_401_V85M length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYMLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.S591L_401_S399L length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNLLP

>SHROOM4_ARID3A_ENST00000289292_ENST00000263620_50556901_960091_3-gene_p.R330W_401_R138W length=401AA
MENRPGSFQYVPVQLQGGAPWGFTLKGGLEHCEPLTVSKLYELDGDPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKWGLSNPNELQAAI
DSNRREGRRQSFGGSLFAYSPGGAHGMLSSPKLPVSSLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESAEPPEKKMALVADEQQRLMQRALQQNFLAMAAQLPMS
IRINSQASESRQDSAVNLTGTNGSNSISMSVEINGIMYTGVLFAQPPAPTPTSAPNKGGGGGGGSSSNAGGRGGNTGTSGGQAGPAGLSTPSTSTSNNSLP

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000289292_ENST00000263620_50556901_960091	TCGA-06-5416-01A	3-gene	p.R450W	401	R258W
ENST00000289292_ENST00000263620_50556901_960091	TCGA-28-1760-01A	3-gene	p.M529I	401	M337I
ENST00000289292_ENST00000263620_50556901_960091	TCGA-33-4538-01A	3-gene	p.L245V	401	L53V
ENST00000289292_ENST00000263620_50556901_960091	TCGA-97-A4M3-01A	3-gene	p.N514I	401	N322I
ENST00000289292_ENST00000263620_50556901_960091	TCGA-A5-A0G1-01A	3-gene	p.A578V	401	A386V
ENST00000289292_ENST00000263620_50556901_960091	TCGA-AA-3492-01A	3-gene	p.S557G	401	S365G
ENST00000289292_ENST00000263620_50556901_960091	TCGA-AA-3864-01A	3-gene	p.G563S	401	G371S
ENST00000289292_ENST00000263620_50556901_960091	TCGA-AC-A23H-01A	3-gene	p.I289M	401	I97M
ENST00000289292_ENST00000263620_50556901_960091	TCGA-AP-A051-01A	3-gene	p.L322M	401	L130M
ENST00000289292_ENST00000263620_50556901_960091	TCGA-AP-A056-01A	3-gene	p.R330W	401	R138W
ENST00000289292_ENST00000263620_50556901_960091	TCGA-B5-A3FC-01A	3-gene	p.G365R	401	G173R
ENST00000289292_ENST00000263620_50556901_960091	TCGA-B5-A5OC-01A	3-gene	p.A536V	401	A344V
ENST00000289292_ENST00000263620_50556901_960091	TCGA-BF-A1PX-01A	3-gene	p.L245M	401	L53M
ENST00000289292_ENST00000263620_50556901_960091	TCGA-BR-6452-01A	3-gene	p.S557G	401	S365G
ENST00000289292_ENST00000263620_50556901_960091	TCGA-CK-5914-01A	3-gene	p.G365R	401	G173R
ENST00000289292_ENST00000263620_50556901_960091	TCGA-CR-7385-01A	3-gene	p.G237W	401	G45W
ENST00000289292_ENST00000263620_50556901_960091	TCGA-CV-6962-01A	3-gene	p.G554R	401	G362R
ENST00000289292_ENST00000263620_50556901_960091	TCGA-D1-A0ZS-01A	3-gene	p.S557G	401	S365G
ENST00000289292_ENST00000263620_50556901_960091	TCGA-D1-A16N-01A	3-gene	p.A394T	401	A202T
ENST00000289292_ENST00000263620_50556901_960091	TCGA-D3-A1Q3-06A	3-gene	p.G365V	401	G173V
ENST00000289292_ENST00000263620_50556901_960091	TCGA-D3-A2JP-06A	3-gene	p.L270I	401	L78I
ENST00000289292_ENST00000263620_50556901_960091	TCGA-DA-A1HY-06A	3-gene	p.E524K	401	E332K
ENST00000289292_ENST00000263620_50556901_960091	TCGA-DD-A73C-01A	3-gene	p.R412L	401	R220L
ENST00000289292_ENST00000263620_50556901_960091	TCGA-DF-A2KN-01A	3-gene	p.G555S	401	G363S
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EE-A2GC-06A	3-gene	p.P547S	401	P355S
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EE-A2GJ-06A	3-gene	p.S333N	401	S141N
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EE-A2MG-06A	3-gene	p.G237W	401	G45W
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EE-A2MS-06A	3-gene	p.P547L	401	P355L
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EO-A22S-01A	3-gene	p.G555S	401	G363S
ENST00000289292_ENST00000263620_50556901_960091	TCGA-EY-A549-01A	3-gene	p.A456V	401	A264V
ENST00000289292_ENST00000263620_50556901_960091	TCGA-FI-A2D5-01A	3-gene	p.V523A	401	V331A
ENST00000289292_ENST00000263620_50556901_960091	TCGA-FS-A1Z0-06A	3-gene	p.P263H	401	P71H
ENST00000289292_ENST00000263620_50556901_960091	TCGA-FS-A1Z4-06A	3-gene	p.P410H	401	P218H
ENST00000289292_ENST00000263620_50556901_960091	TCGA-G9-6494-01A	3-gene	p.G283D	401	G91D
ENST00000289292_ENST00000263620_50556901_960091	TCGA-H2-A422-01A	3-gene	p.R261H	401	R69H
ENST00000289292_ENST00000263620_50556901_960091	TCGA-HU-A4G9-01A	3-gene	p.G555S;p.S557G	401	G363S;S365G
ENST00000289292_ENST00000263620_50556901_960091	TCGA-HU-A4GN-01A	3-gene	p.P458T	401	P266T
ENST00000289292_ENST00000263620_50556901_960091	TCGA-IB-7651-01A	3-gene	p.L278M	401	L86M
ENST00000289292_ENST00000263620_50556901_960091	TCGA-IN-8462-01A	3-gene	p.N548K	401	N356K
ENST00000289292_ENST00000263620_50556901_960091	TCGA-JW-A5VL-01A	3-gene	p.T316S	401	T124S
ENST00000289292_ENST00000263620_50556901_960091	TCGA-Q1-A73O-01A	3-gene	p.M491I	401	M299I
ENST00000289292_ENST00000263620_50556901_960091	TCGA-QQ-A8VF-01A	3-gene	p.V277M	401	V85M
ENST00000289292_ENST00000263620_50556901_960091	TCGA-QQ-A8VG-01A	3-gene	p.S591L	401	S399L
ENST00000289292_ENST00000263620_50556901_960091	TCGA-VQ-A924-01A	3-gene	p.R330W	401	R138W

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for SHROOM4_ARID3A

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		UCEC	TCGA-BK-A0CC-01A	SHROOM4	chrX	50556901	-	ARID3A	chr19	50556901	+
ChimerDB		UCEC	TCGA-BK-A0CC-01A	SHROOM4	chrX	50556901	-	ARID3A	chr19	960091	+
ChimerDB		UCEC	TCGA-BK-A0CC-01B	SHROOM4	chrX	50556901	-	ARID3A	chr19	50556901	+
ChimerDB		UCEC	TCGA-BK-A0CC	SHROOM4	chrX	50556901	-	ARID3A	chr19	50556901	+
WashU		UCEC	TCGA-BK-A0CC-01A	SHROOM4	chrX	50556902	-	ARID3A	chr19	960092	+
cBioPortal	UCEC_TCGA_PAN_CAN_ATLAS_2018	UCEC	TCGA-BK-A0CC-01	SHROOM4	chrX	50813902		ARID3A	chr19	960092

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for SHROOM4_ARID3A

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status