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Fusion gene:DENND1A_PSMB7 (FusionGDB2 ID:HG57706TG5695) |
Fusion Gene Summary for DENND1A_PSMB7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DENND1A_PSMB7 | Fusion gene ID: hg57706tg5695 | Hgene | Tgene | Gene symbol | DENND1A | PSMB7 | Gene ID | 57706 | 5695 |
| Gene name | DENN domain containing 1A | proteasome 20S subunit beta 7 | |
| Synonyms | FAM31A|KIAA1608 | - | |
| Cytomap | 9q33.3 | 9q33.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DENN domain-containing protein 1ADENN/MADD domain containing 1Aconnecdenn 1 | proteasome subunit beta type-7epididymis secretory sperm binding proteinmacropain chain Zmulticatalytic endopeptidase complex chain Zproteasome (prosome, macropain) subunit, beta type, 7proteasome catalytic subunit 2proteasome subunit Zproteasome s | |
| Modification date | 20240403 | 20240305 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000373618, ENST00000373620, ENST00000373624, ENST00000394215, ENST00000394219, ENST00000542603, ENST00000473039, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 25 X 26 X 21=13650 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 14 X 17 X 20=4760 |
| # samples | 50 | 334 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(50/13650*10)=-4.77082904603249 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(334/4760*10)=-0.511113470833891 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DENND1A [Title/Abstract] AND PSMB7 [Title/Abstract] AND fusion [Title/Abstract] Genomic imbalances defining novel intellectual disability associated loci (pmid: 31277718) | ||
| Most frequent breakpoint | DENND1A(126414291)-PSMB7(127146935), # samples:3 | ||
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Fusion Gene Breakpoints for DENND1A_PSMB7 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 |
| DENND1A | chr9 | 126692167 | PSMB7 | chr9 | 127119194 |
| DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 |
| DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 |
| DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127146935 |
| DENND1A | chr9 | 126554865 | PSMB7 | chr9 | 127146935 |
| DENND1A | chr9 | 126641230 | PSMB7 | chr9 | 127146935 |
| DENND1A | chr9 | 126202639 | PSMB7 | chr9 | 127119194 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
| DENND1A | chr9 | 126433567 | PSMB7 | chr9 | 127177709 | DUP |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for DENND1A_PSMB7 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DENND1A | GO:0032483 | regulation of Rab protein signal transduction | 20937701 |
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Fusion Genomic Features for DENND1A_PSMB7 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - | 1.59e-15 | 1.00e+00 |
| DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - | 5.22e-10 | 1.00e+00 |
| DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - | 4.21e-06 | 1.00e+00 |
| DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - | 5.20e-08 | 1.00e+00 |
| DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - | 3.79e-05 | 1.00e+00 |
| DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - | 1.25e-11 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for DENND1A_PSMB7 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-3UTR | ENST00000542603 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000259457 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000498485 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000259457 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000498485 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000259457 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000498485 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5CDS-5UTR | ENST00000542603 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5CDS-5UTR | ENST00000542603 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000473039 | ENST00000536392 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000473039 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000473039 | ENST00000536392 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-3UTR | ENST00000542603 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000373618 | ENST00000259457 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000373618 | ENST00000498485 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000394215 | ENST00000259457 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000394215 | ENST00000498485 | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000259457 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000259457 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000259457 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000498485 | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000498485 | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000498485 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000473039 | ENST00000536392 | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000542603 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000542603 | ENST00000259457 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000542603 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - |
| 5UTR-5UTR | ENST00000542603 | ENST00000498485 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| 5UTR-5UTR | ENST00000542603 | ENST00000536392 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 4.02e-02 |
| ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.88e-02 |
| ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 4.55e-02 |
| ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.28e-02 |
| ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.12e-02 |
| ENST00000542603 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 7.09e-03 |
| ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126202638 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.55e-02 |
| ENST00000542603 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 7.69e-02 |
| ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126692167 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.97e-01 |
| ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.44e-02 |
| ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.51e-02 |
| ENST00000394219 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.08e-02 |
| ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.73e-02 |
| ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.89e-02 |
| ENST00000394215 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.39e-02 |
| ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126692167 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.26e-01 |
| ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.74e-02 |
| ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.89e-02 |
| ENST00000373624 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.34e-02 |
| ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126692167 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.53e-01 |
| ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.66e-02 |
| ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 2.04e-02 |
| ENST00000373620 | ENST00000536392 | DENND1A | chr9 | 126345447 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 1.44e-02 |
| ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126519981 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 3.59e-02 |
| ENST00000373618 | ENST00000536392 | DENND1A | chr9 | 126414291 | PSMB7 | chr9 | 127119194 | 0.00e+00 | 3.88e-02 |
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Fusion Protein Retained/Non-Retained Functional Features for DENND1A_PSMB7 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
 |
| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
| No matching images found for ${hg}_${tg}. |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for DENND1A_PSMB7 |
| In-frame Fusion Transcript Sequences. |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
>DENND1A_PSMB7_ENST00000373618_ENST00000536392_126345447_127119194 length=1064nt Breakpoint=1064nt GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGG GGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGA AGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTC TGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGT TGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCC TCCCAAACGACGTG >DENND1A_PSMB7_ENST00000373618_ENST00000536392_126414291_127119194 length=815nt Breakpoint=815nt GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGG GGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGA AGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTC TGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGT TGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACT >DENND1A_PSMB7_ENST00000373618_ENST00000536392_126519981_127119194 length=499nt Breakpoint=499nt GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGG GGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGA AGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG >DENND1A_PSMB7_ENST00000373620_ENST00000536392_126345447_127119194 length=1088nt Breakpoint=1088nt ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCC GGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCA CTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATC AGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTG TGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGT ACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAA CCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTG >DENND1A_PSMB7_ENST00000373620_ENST00000536392_126414291_127119194 length=839nt Breakpoint=839nt ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCC GGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCA CTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATC AGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTG TGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACT >DENND1A_PSMB7_ENST00000373620_ENST00000536392_126519981_127119194 length=523nt Breakpoint=523nt ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCC GGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCA CTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG >DENND1A_PSMB7_ENST00000373620_ENST00000536392_126692167_127119194 length=238nt Breakpoint=238nt ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCC GGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAA >DENND1A_PSMB7_ENST00000373624_ENST00000536392_126345447_127119194 length=1069nt Breakpoint=1069nt GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCG GGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGT GCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGA AACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAA CATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCC GCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCA GAGCCTCCCAAACGACGTG >DENND1A_PSMB7_ENST00000373624_ENST00000536392_126414291_127119194 length=820nt Breakpoint=820nt GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCG GGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGT GCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGA AACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAA CATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACT >DENND1A_PSMB7_ENST00000373624_ENST00000536392_126519981_127119194 length=504nt Breakpoint=504nt GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCG GGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGT GCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG >DENND1A_PSMB7_ENST00000373624_ENST00000536392_126692167_127119194 length=219nt Breakpoint=219nt GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCG GGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAA >DENND1A_PSMB7_ENST00000394215_ENST00000536392_126345447_127119194 length=1056nt Breakpoint=1056nt CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGC CAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCA GGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAA CTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTG TACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAAC GACGTG >DENND1A_PSMB7_ENST00000394215_ENST00000536392_126414291_127119194 length=807nt Breakpoint=807nt CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGC CAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCA GGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAA CTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTG TACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACT >DENND1A_PSMB7_ENST00000394215_ENST00000536392_126519981_127119194 length=491nt Breakpoint=491nt CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGC CAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCA GGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG >DENND1A_PSMB7_ENST00000394219_ENST00000536392_126345447_127119194 length=961nt Breakpoint=961nt GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGG GCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCA GAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTA CACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAA TAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTA CCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAA TGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTG >DENND1A_PSMB7_ENST00000394219_ENST00000536392_126414291_127119194 length=712nt Breakpoint=712nt GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGG GCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCA GAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTA CACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAA TAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACT >DENND1A_PSMB7_ENST00000394219_ENST00000536392_126519981_127119194 length=396nt Breakpoint=396nt GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGG GCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCA GAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAG >DENND1A_PSMB7_ENST00000394219_ENST00000536392_126692167_127119194 length=226nt Breakpoint=226nt GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGG GCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAA >DENND1A_PSMB7_ENST00000542603_ENST00000536392_126345447_127119194 length=288nt Breakpoint=288nt GAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATG CCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTG >DENND1A_PSMB7_ENST00000373624_ENST00000536392_126202638_127119194 length=1690nt Breakpoint=1690nt GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCG GGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGT GCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGA AACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAA CATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCC GCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCA GAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTGAAAATCGAGCCGGAGGA GCCGATCACTTTCTGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGATGGTCGATTAGATCTTCTCAATTCCGGCGAAGGTTTCAGTGA TGTTTTTGAAGAGGAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTT CGCAAAAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAAGACTGCACCGTCCCCACTGGTGGAGGCCAAGGACCCCAAGCT CCGAGAAGACCGGCGGCCAATCACAGTCCACTTTGGACAG >DENND1A_PSMB7_ENST00000542603_ENST00000536392_126202638_127119194 length=783nt Breakpoint=783nt GAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATG CCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGGAGGAGCCGATC ACTTTCTGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGATGGTCGATTAGATCTTCTCAATTCCGGCGAAGGTTTCAGTGATGTTTTT GAAGAGGAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTTCGCAAAA GATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAAGACTGCACCGTCCCCACTGGTGGAGGCCAAGGACCCCAAGCTCCGAGAA GACCGGCGGCCAATCACAGTCCACTTTGGACAG >DENND1A_PSMB7_ENST00000394219_ENST00000536392_126202638_127119194 length=1582nt Breakpoint=1582nt GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGG GCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCA GAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTA CACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAA TAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTA CCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAA TGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTT CTTCGGTAGCTACCGAAACGCTCTGAAAATCGAGCCGGAGGAGCCGATCACTTTCTGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGA TGGTCGATTAGATCTTCTCAATTCCGGCGAAGGTTTCAGTGATGTTTTTGAAGAGGAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGT AAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTTCGCAAAAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAA GACTGCACCGTCCCCACTGGTGGAGGCCAAGGACCCCAAGCTCCGAGAAGACCGGCGGCCAATCACAGTCCACTTTGGACAG >DENND1A_PSMB7_ENST00000373620_ENST00000536392_126202638_127119194 length=1709nt Breakpoint=1709nt ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCC GGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCA CTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATC AGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTG TGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGT ACATCCCCGTGCTGCCGCCGCATCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAA CCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTC TGAAAATCGAGCCGGAGGAGCCGATCACTTTCTGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGATGGTCGATTAGATCTTCTCAATT CCGGCGAAGGTTTCAGTGATGTTTTTGAAGAGGAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCA TGAAGACTGTCTACAAGTTCGCAAAAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAAGACTGCACCGTCCCCACTGGTGG AGGCCAAGGACCCCAAGCTCCGAGAAGACCGGCGGCCAATCACAGTCCACTTTGGACAG >DENND1A_PSMB7_ENST00000394215_ENST00000536392_126202638_127119194 length=1677nt Breakpoint=1677nt CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGC CAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCA GGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAA CTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTG TACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAAC GACGTGATCTCTTCCCTGAAGAACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTGAAAATCGAGCCGGAGGAGCCGATCACTTTC TGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGATGGTCGATTAGATCTTCTCAATTCCGGCGAAGGTTTCAGTGATGTTTTTGAAGAG GAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTTCGCAAAAGATCAT GCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAAGACTGCACCGTCCCCACTGGTGGAGGCCAAGGACCCCAAGCTCCGAGAAGACCGG CGGCCAATCACAGTCCACTTTGGACAG >DENND1A_PSMB7_ENST00000373618_ENST00000536392_126202638_127119194 length=1685nt Breakpoint=1685nt GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGG GGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGA AGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTC TGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTGGCTGTGGATGTTAACAACATGT TGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCC TCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTGAAAATCGAGCCGGAGGAGCCGA TCACTTTCTGTGAGGAAGCCTTCGTGTCCCACTACCGCTCCGGAGCCATGAGGCAGTTCCTGCAGAACGCCACACAGCTGCAGCTCTTCAAGCAGTTTATTGATGGTCGATTAGATCTTCTCAATTCCGGCGAAGGTTTCAGTGATGTTT TTGAAGAGGAAATCAACATGGGCGAGTACGCTGGCAGTGACAAACTGTACCATCAGTGGCTCTCCACTGTCCGGAAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTTCGCAA AAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAGGACATTGCCGAGAATGGCTGCGCCCCCACCCCAGAAGAGCAGCTGCCAAAGACTGCACCGTCCCCACTGGTGGAGGCCAAGGACCCCAAGCTCCGAG AAGACCGGCGGCCAATCACAGTCCACTTTGGACAG |
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Fusion Protein Sequence for DENND1A_PSMB7 |
| In-frame Fusion Protein Sequences. |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for DENND1A_PSMB7 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
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Fusion Gene Exprssed Samples for DENND1A_PSMB7 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | GBM | TCGA-28-5216-01A | DENND1A | chr9 | 126519981 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | OV | TCGA-24-2271-01A | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | SKCM | TCGA-EE-A2MC-06A | DENND1A | chr9 | 126345447 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | STAD | TCGA-BR-8078-01A | DENND1A | chr9 | 126692167 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | STAD | TCGA-IN-8462 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | STAD | TCGA-IN-8462 | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - | |
| ChimerDB | UCEC | TCGA-AX-A3FX-01A | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - | |
| ChimerDB | UCEC | TCGA-AX-A3FX-01A | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - | |
| ChimerDB | UCEC | TCGA-AX-A3FX | DENND1A | chr9 | 126554865 | - | PSMB7 | chr9 | 127146935 | - | |
| ChimerDB | UCS | TCGA-N5-A4RT-01A | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - | |
| ChimerDB | UCS | TCGA-N5-A4RT | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127119194 | - | |
| ChimerDB | UCS | TCGA-N5-A4RT | DENND1A | chr9 | 126414291 | - | PSMB7 | chr9 | 127146935 | - | |
| cBioPortal | CCLE_BROAD_2019 | MIXED | MJ_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | DENND1A | chr9 | 126641230 | PSMB7 | chr9 | 127146935 | ||
| cBioPortal | CCLE_BROAD_2019 | MIXED | PECAPJ49_UPPER_AERODIGESTIVE_TRACT | DENND1A | chr9 | 126202639 | PSMB7 | chr9 | 127119194 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
| dbVar | nstd151 | Unknown_Cell | DENND1A | chr9 | 126433567 | PSMB7 | chr9 | 127177709 | DUP |
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Related Drugs for DENND1A_PSMB7 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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