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Fusion gene:TMPRSS2_TMEFF2 (FusionGDB2 ID:HG7113TG23671) |
Fusion Gene Summary for TMPRSS2_TMEFF2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMPRSS2_TMEFF2 | Fusion gene ID: hg7113tg23671 | Hgene | Tgene | Gene symbol | TMPRSS2 | TMEFF2 | Gene ID | 7113 | 23671 |
| Gene name | transmembrane serine protease 2 | transmembrane protein with EGF like and two follistatin like domains 2 | |
| Synonyms | PRSS10 | CT120.2|HPP1|TENB2|TPEF|TR|TR-2 | |
| Cytomap | 21q22.3 | 2q32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transmembrane protease serine 2epitheliasinserine protease 10transmembrane protease, serine 2 | tomoregulin-2cancer/testis antigen family 120, member 2hyperplastic polyposis protein 1transmembrane protein TENB2transmembrane protein with EGF-like and two follistatin-like domains | |
| Modification date | 20240407 | 20240411 | |
| UniProtAcc | O15393 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000332149, ENST00000398585, ENST00000458356, ENST00000497881, | ENST00000497881, ENST00000332149, ENST00000398585, ENST00000458356, | |
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 147 X 821 X 24=2896488 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 1 X 6 X 2=12 |
| # samples | 1415 | 7 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(1415/2896488*10)=-7.67735882472872 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(7/12*10)=2.54432051622381 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TMPRSS2 [Title/Abstract] AND TMEFF2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | TMPRSS2(42852402)-TMEFF2(192863931), # samples:2 | ||
| Fusion gene breakpoints across TMPRSS2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across TMEFF2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Breakpoints for TMPRSS2_TMEFF2 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863934 |
| TMPRSS2 | chr21 | 42852403 | TMEFF2 | chr2 | 192863934 |
| TMPRSS2 | chr21 | 41480476 | TMEFF2 | chr2 | 191999208 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for TMPRSS2_TMEFF2 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMPRSS2 | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TMPRSS2 | GO:0006508 | proteolysis | 21068237|24227843 |
| Hgene | TMPRSS2 | GO:0046598 | positive regulation of viral entry into host cell | 21068237|24227843|32404436 |
| Tgene | TMEFF2 | GO:0030336 | negative regulation of cell migration | 24632071 |
| Tgene | TMEFF2 | GO:0044319 | wound healing, spreading of cells | 24632071 |
| Tgene | TMEFF2 | GO:0051497 | negative regulation of stress fiber assembly | 24632071 |
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Fusion Genomic Features for TMPRSS2_TMEFF2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - | 2.22e-03 | 9.98e-01 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
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Fusion Gene ORF Annotations for TMPRSS2_TMEFF2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000332149 | ENST00000487771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| Frame-shift | ENST00000398585 | ENST00000487771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| Frame-shift | ENST00000458356 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| Frame-shift | ENST00000458356 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| Frame-shift | ENST00000458356 | ENST00000487771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| In-frame | ENST00000332149 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| In-frame | ENST00000332149 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| In-frame | ENST00000398585 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| In-frame | ENST00000398585 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863931 | - |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000332149 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 707 | 358 |
| ENST00000332149 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 707 | 249 |
| ENST00000398585 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 744 | 402 |
| ENST00000398585 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 744 | 386 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000332149 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 1.15e-03 | 9.99e-01 |
| ENST00000332149 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 3.16e-03 | 9.97e-01 |
| ENST00000398585 | ENST00000272771 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 1.25e-03 | 9.99e-01 |
| ENST00000398585 | ENST00000392314 | TMPRSS2 | chr21 | 42852402 | TMEFF2 | chr2 | 192863931 | 3.83e-03 | 9.96e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
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Fusion Protein Retained/Non-Retained Functional Features for TMPRSS2_TMEFF2 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
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| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
TMPRSS2_TMEFF2_chr21-42852402_chr2-192863931.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 118_148 | 190.66666666666666 | 493.0 | Domain | LDL-receptor class A |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 1_84 | 190.66666666666666 | 493.0 | Topological domain | Cytoplasmic |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 85_105 | 190.66666666666666 | 493.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 356_374 | 178.66666666666666 | 375.0 | Compositional bias | Polar residues |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 181_229 | 178.66666666666666 | 375.0 | Domain | Kazal-like 2 |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 261_301 | 178.66666666666666 | 375.0 | Domain | EGF-like |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 303_320 | 178.66666666666666 | 375.0 | Region | Required for shedding |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 353_374 | 178.66666666666666 | 375.0 | Region | Disordered |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 342_374 | 178.66666666666666 | 375.0 | Topological domain | Cytoplasmic |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 321_341 | 178.66666666666666 | 375.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 149_242 | 190.66666666666666 | 493.0 | Domain | SRCR |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 256_492 | 190.66666666666666 | 493.0 | Domain | Peptidase S1 |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 340_470 | 190.66666666666666 | 493.0 | Region | HKU1-CoV S protein-binding |
| Hgene | TMPRSS2 | chr21:42852402 | chr2:192863931 | ENST00000332149 | O15393 | 6 | 14 | 106_492 | 190.66666666666666 | 493.0 | Topological domain | Extracellular |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 90_137 | 178.66666666666666 | 375.0 | Domain | Kazal-like 1 |
| Tgene | TMEFF2 | chr21:42852402 | chr2:192863931 | ENST00000272771 | Q9UIK5 | 4 | 10 | 41_320 | 178.66666666666666 | 375.0 | Topological domain | Extracellular |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Fusion Transcript Sequence for TMPRSS2_TMEFF2 |
| In-frame Fusion Transcript Sequences. |
>TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931 length=1590nt Breakpoint=707nt CGAGTAGGCGCGAGCTAAGCAGGAGGCGGAGGCGGAGGCGGAGGGCGAGGGGCGGGGAGCGCCGCCTGGAGCGCGGCAGGTCATATTGAACATTCCAGATACCTATCATTACTCGATGCTGTTGATAACAGCAAGATGGCTTTGAACTCA GGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGG GTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCGGGACAGTGTGCACCTCAAAGACTAAGAAAGCACTGTGCATCACCTTGACCCTGGGGACCTTCCTCGTGGGAGCTGCGCTGGCCGCTGGCCTACTC TGGAAGTTCATGGGCAGCAAGTGCTCCAACTCTGGGATAGAGTGCGACTCCTCAGGTACCTGCATCAACCCCTCTAACTGGTGTGATGGCGTGTCACACTGCCCCGGCGGGGAGGACGAGAATCGGTGTGTTCGCCTCTACGGACCAAAC TTCATCCTTCAGGTGTACTCATCTCAGAGGAAGTCCTGGCACCCTGTGTGCCAAGACGACTGGAACGAGAACTACGGGCGGGCGGCCTGCAGGGACATGGGCTATAAGTGTGTGTGTAATATTGACTGTTCTCAAACCAACTTCAATCCC CTCTGCGCTTCTGATGGGAAATCTTATGATAATGCATGCCAAATCAAAGAAGCATCGTGTCAGAAACAGGAGAAAATTGAAGTCATGTCTTTGGGTCGATGTCAAGATAACACAACTACAACTACTAAGTCTGAAGATGGGCATTATGCA AGAACAGATTATGCAGAGAATGCTAACAAATTAGAAGAAAGTGCCAGAGAACACCACATACCTTGTCCGGAACATTACAATGGCTTCTGCATGCATGGGAAGTGTGAGCATTCTATCAATATGCAGGAGCCATCTTGCAGGTGTGATGCT GGTTATACTGGACAACACTGTGAAAAAAAGGACTACAGTGTTCTATACGTTGTTCCCGGTCCTGTACGATTTCAGTATGTCTTAATCGCAGCTGTGATTGGAACAATTCAGATTGCTGTCATCTGTGTGGTGGTCCTCTGCATCACAAGG AAATGCCCCAGAAGCAACAGAATTCACAGACAGAAGCAAAATACAGGGCACTACAGTTCAGACAATACAACAAGAGCGTCCACGAGGTTAATCTAAAGGGAGCATGTTTCACAGTGGCTGGACTACCGAGAGCTTGGACTACACAATACA GTATTATAGACAAAAGAATAAGACAAGAGATCTACACATGTTGCCTTGCATTTGTGGTAATCTACACCAATGAAAACATGTACTACAGCTATATTTGATTATGTATGGATATATTTGAAATAGTATACATTGTCTTGATGTTTTTTCTGT AATGTAAATAAACTATTTATATCACACAATATAGTTTTTTCTTTCCCATGTATTTGTTATATATAATAAATACTCAGTGATGAGAAAAAA >TMPRSS2_TMEFF2_ENST00000332149_ENST00000392314_42852402_192863931 length=2621nt Breakpoint=707nt CGAGTAGGCGCGAGCTAAGCAGGAGGCGGAGGCGGAGGCGGAGGGCGAGGGGCGGGGAGCGCCGCCTGGAGCGCGGCAGGTCATATTGAACATTCCAGATACCTATCATTACTCGATGCTGTTGATAACAGCAAGATGGCTTTGAACTCA GGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCAGTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGG GTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCGGGACAGTGTGCACCTCAAAGACTAAGAAAGCACTGTGCATCACCTTGACCCTGGGGACCTTCCTCGTGGGAGCTGCGCTGGCCGCTGGCCTACTC TGGAAGTTCATGGGCAGCAAGTGCTCCAACTCTGGGATAGAGTGCGACTCCTCAGGTACCTGCATCAACCCCTCTAACTGGTGTGATGGCGTGTCACACTGCCCCGGCGGGGAGGACGAGAATCGGTGTGTTCGCCTCTACGGACCAAAC TTCATCCTTCAGGTGTACTCATCTCAGAGGAAGTCCTGGCACCCTGTGTGCCAAGACGACTGGAACGAGAACTACGGGCGGGCGGCCTGCAGGGACATGGGCTATAAGTGTGTGTGTAATATTGACTGTTCTCAAACCAACTTCAATCCC CTCTGCGCTTCTGATGGGAAATCTTATGATAATGCATGCCAAATCAAAGAAGCATCGTGTCAGAAACAGGAGAAAATTGAAGTCATGTCTTTGGGTCGATGTCAAGATAACACAACTACAACTACTAAGTCTGAAGATGGGCATTATGCA AGAACAGATTATGCAGAGAATGCTAACAAATTAGAAGAAAGTGCCAGAGAACACCACATACCTTGTCCGGAACATTACAATGGCTTCTGCATGCATGGGAAGTGTGAGCATTCTATCAATATGCAGGAGCCATCTTGCAGGTGTGATGCT GGTTATACTGGACAACACTGTGAAAAAAAGGACTACAGTGTTCTATACGTTGTTCCCGGTCCTGTACGATTTCAGTATGTCTTAATCGCAGCTGTGATTGGAACAATTCAGATTGCTGTCATCTGTGTGGTGGTCCTCTGCATCACAAGG GCCAAACTTTAGGTAATAGCATTGGACTGAGATTTGTAAACTTTCCAACCTTCCAGGAAATGCCCCAGAAGCAACAGAATTCACAGACAGAAGCAAAATACAGGGCACTACAGTTCAGACAATACAACAAGAGCGTCCACGAGGTTAATC TAAAGGGAGCATGTTTCACAGTGGCTGGACTACCGAGAGCTTGGACTACACAATACAGTATTATAGACAAAAGAATAAGACAAGAGATCTACACATGTTGCCTTGCATTTGTGGTAATCTACACCAATGAAAACATGTACTACAGCTATA TTTGATTATGTATGGATATATTTGAAATAGTATACATTGTCTTGATGTTTTTTCTGTAATGTAAATAAACTATTTATATCACACAATATAGTTTTTTCTTTCCCATGTATTTGTTATATATAATAAATACTCAGTGATGAGAAAAAATTG GCATTCTTAAATTTGCGGTATCTCATAACTGTAAATATAATCAGACTAGTACAATCTGTACAGCTACCAATATTTCATGTTTCTTCTCATCTTGAGACAGCACATTAGTTCGTACAGGACTCAGTGGCTAGGTTTTGAATGATTCCAAGA TCAAGGGAAATGATGGTTATTGGAAAAGAGAAAAAATAATTTACTTTATATCGAGTGAGGATAAAATATTTCCGATCTTTGAATCATCTCTATTTCATCAACTTTCTTCCCTGGTCTTCCATTTTCATCCCTAGAGCAGAAAAATCTCTG GCATATAAACTAAATAAAAGAAGAAGGGGAGGGAAAGTGTTTTATAACTCATAAAGGAGAGGGAAAGAAAATATTGGTTTTTATTGGGGAAGTAGCTTAGAATCCCCCAGTTAAGTGCATATATCTGAACTTACTGAACAAGTTACATAC TAGGTATACACAGAGTGGCAAAATATATTCCATTTAGGTGGGTGGAATTACCAGGGGAAAAATGTAATAACACCACTAGATGTGAAACACCAAAATCGTGAATTCTCAAAAGCACCATACAATATGTATAGTATATAGTTCTTTGAAAAG AAGTTAGAATCACAACCAATACCCCATGAATAGCTTTGTGGCTAATGCAGCACCATAATTTGTAATGGAACTAAGATGATGATGACGATATTTCATGAAAACAGAGAGATGTTTTGAGCATATTTATGTGGTGAGGTAAGAAAGAAAATT AATCCTATAGCATCTGAAAGACCTCACTGGGAAGTTGGTATGGATTTTTGTTTGATTTGTGCATACAAATAGGTATCACAACTTGATCTGGAAAAAATAAGCTGTGAAAATTCTCAAGGAATAAGATGAAAATAAATCAATTATTATCAT TTAGCTCTGCAAAGCTTTCCATGGCTAACACAGTAAATTTAAATAAAGCTCTCTTTGTCTCCTTCAAATAA >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931 length=1627nt Breakpoint=744nt ACCAGGGTCCCGGCTCGGGGTCCGGGCTGGGGAGGGGAACCTGGGCGCCTGGGACCCGCCGATGCCCCCTGCCCCGCCCGGAGGTGAAAGCGGGTGTGAGGAGCGCGGCGCGGCAGGTCATATTGAACATTCCAGATACCTATCATTACT CGATGCTGTTGATAACAGCAAGATGGCTTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCA GTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCGGGACAGTGTGCACCTCAAAGACTAAGAAAGCACTGTGCATCACCTTGACCCTGGGGAC CTTCCTCGTGGGAGCTGCGCTGGCCGCTGGCCTACTCTGGAAGTTCATGGGCAGCAAGTGCTCCAACTCTGGGATAGAGTGCGACTCCTCAGGTACCTGCATCAACCCCTCTAACTGGTGTGATGGCGTGTCACACTGCCCCGGCGGGGA GGACGAGAATCGGTGTGTTCGCCTCTACGGACCAAACTTCATCCTTCAGGTGTACTCATCTCAGAGGAAGTCCTGGCACCCTGTGTGCCAAGACGACTGGAACGAGAACTACGGGCGGGCGGCCTGCAGGGACATGGGCTATAAGTGTGT GTGTAATATTGACTGTTCTCAAACCAACTTCAATCCCCTCTGCGCTTCTGATGGGAAATCTTATGATAATGCATGCCAAATCAAAGAAGCATCGTGTCAGAAACAGGAGAAAATTGAAGTCATGTCTTTGGGTCGATGTCAAGATAACAC AACTACAACTACTAAGTCTGAAGATGGGCATTATGCAAGAACAGATTATGCAGAGAATGCTAACAAATTAGAAGAAAGTGCCAGAGAACACCACATACCTTGTCCGGAACATTACAATGGCTTCTGCATGCATGGGAAGTGTGAGCATTC TATCAATATGCAGGAGCCATCTTGCAGGTGTGATGCTGGTTATACTGGACAACACTGTGAAAAAAAGGACTACAGTGTTCTATACGTTGTTCCCGGTCCTGTACGATTTCAGTATGTCTTAATCGCAGCTGTGATTGGAACAATTCAGAT TGCTGTCATCTGTGTGGTGGTCCTCTGCATCACAAGGAAATGCCCCAGAAGCAACAGAATTCACAGACAGAAGCAAAATACAGGGCACTACAGTTCAGACAATACAACAAGAGCGTCCACGAGGTTAATCTAAAGGGAGCATGTTTCACA GTGGCTGGACTACCGAGAGCTTGGACTACACAATACAGTATTATAGACAAAAGAATAAGACAAGAGATCTACACATGTTGCCTTGCATTTGTGGTAATCTACACCAATGAAAACATGTACTACAGCTATATTTGATTATGTATGGATATA TTTGAAATAGTATACATTGTCTTGATGTTTTTTCTGTAATGTAAATAAACTATTTATATCACACAATATAGTTTTTTCTTTCCCATGTATTTGTTATATATAATAAATACTCAGTGATGAGAAAAAA >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931 length=2658nt Breakpoint=744nt ACCAGGGTCCCGGCTCGGGGTCCGGGCTGGGGAGGGGAACCTGGGCGCCTGGGACCCGCCGATGCCCCCTGCCCCGCCCGGAGGTGAAAGCGGGTGTGAGGAGCGCGGCGCGGCAGGTCATATTGAACATTCCAGATACCTATCATTACT CGATGCTGTTGATAACAGCAAGATGGCTTTGAACTCAGGGTCACCACCAGCTATTGGACCTTACTATGAAAACCATGGATACCAACCGGAAAACCCCTATCCCGCACAGCCCACTGTGGTCCCCACTGTCTACGAGGTGCATCCGGCTCA GTACTACCCGTCCCCCGTGCCCCAGTACGCCCCGAGGGTCCTGACGCAGGCTTCCAACCCCGTCGTCTGCACGCAGCCCAAATCCCCATCCGGGACAGTGTGCACCTCAAAGACTAAGAAAGCACTGTGCATCACCTTGACCCTGGGGAC CTTCCTCGTGGGAGCTGCGCTGGCCGCTGGCCTACTCTGGAAGTTCATGGGCAGCAAGTGCTCCAACTCTGGGATAGAGTGCGACTCCTCAGGTACCTGCATCAACCCCTCTAACTGGTGTGATGGCGTGTCACACTGCCCCGGCGGGGA GGACGAGAATCGGTGTGTTCGCCTCTACGGACCAAACTTCATCCTTCAGGTGTACTCATCTCAGAGGAAGTCCTGGCACCCTGTGTGCCAAGACGACTGGAACGAGAACTACGGGCGGGCGGCCTGCAGGGACATGGGCTATAAGTGTGT GTGTAATATTGACTGTTCTCAAACCAACTTCAATCCCCTCTGCGCTTCTGATGGGAAATCTTATGATAATGCATGCCAAATCAAAGAAGCATCGTGTCAGAAACAGGAGAAAATTGAAGTCATGTCTTTGGGTCGATGTCAAGATAACAC AACTACAACTACTAAGTCTGAAGATGGGCATTATGCAAGAACAGATTATGCAGAGAATGCTAACAAATTAGAAGAAAGTGCCAGAGAACACCACATACCTTGTCCGGAACATTACAATGGCTTCTGCATGCATGGGAAGTGTGAGCATTC TATCAATATGCAGGAGCCATCTTGCAGGTGTGATGCTGGTTATACTGGACAACACTGTGAAAAAAAGGACTACAGTGTTCTATACGTTGTTCCCGGTCCTGTACGATTTCAGTATGTCTTAATCGCAGCTGTGATTGGAACAATTCAGAT TGCTGTCATCTGTGTGGTGGTCCTCTGCATCACAAGGGCCAAACTTTAGGTAATAGCATTGGACTGAGATTTGTAAACTTTCCAACCTTCCAGGAAATGCCCCAGAAGCAACAGAATTCACAGACAGAAGCAAAATACAGGGCACTACAG TTCAGACAATACAACAAGAGCGTCCACGAGGTTAATCTAAAGGGAGCATGTTTCACAGTGGCTGGACTACCGAGAGCTTGGACTACACAATACAGTATTATAGACAAAAGAATAAGACAAGAGATCTACACATGTTGCCTTGCATTTGTG GTAATCTACACCAATGAAAACATGTACTACAGCTATATTTGATTATGTATGGATATATTTGAAATAGTATACATTGTCTTGATGTTTTTTCTGTAATGTAAATAAACTATTTATATCACACAATATAGTTTTTTCTTTCCCATGTATTTG TTATATATAATAAATACTCAGTGATGAGAAAAAATTGGCATTCTTAAATTTGCGGTATCTCATAACTGTAAATATAATCAGACTAGTACAATCTGTACAGCTACCAATATTTCATGTTTCTTCTCATCTTGAGACAGCACATTAGTTCGT ACAGGACTCAGTGGCTAGGTTTTGAATGATTCCAAGATCAAGGGAAATGATGGTTATTGGAAAAGAGAAAAAATAATTTACTTTATATCGAGTGAGGATAAAATATTTCCGATCTTTGAATCATCTCTATTTCATCAACTTTCTTCCCTG GTCTTCCATTTTCATCCCTAGAGCAGAAAAATCTCTGGCATATAAACTAAATAAAAGAAGAAGGGGAGGGAAAGTGTTTTATAACTCATAAAGGAGAGGGAAAGAAAATATTGGTTTTTATTGGGGAAGTAGCTTAGAATCCCCCAGTTA AGTGCATATATCTGAACTTACTGAACAAGTTACATACTAGGTATACACAGAGTGGCAAAATATATTCCATTTAGGTGGGTGGAATTACCAGGGGAAAAATGTAATAACACCACTAGATGTGAAACACCAAAATCGTGAATTCTCAAAAGC ACCATACAATATGTATAGTATATAGTTCTTTGAAAAGAAGTTAGAATCACAACCAATACCCCATGAATAGCTTTGTGGCTAATGCAGCACCATAATTTGTAATGGAACTAAGATGATGATGACGATATTTCATGAAAACAGAGAGATGTT TTGAGCATATTTATGTGGTGAGGTAAGAAAGAAAATTAATCCTATAGCATCTGAAAGACCTCACTGGGAAGTTGGTATGGATTTTTGTTTGATTTGTGCATACAAATAGGTATCACAACTTGATCTGGAAAAAATAAGCTGTGAAAATTC TCAAGGAATAAGATGAAAATAAATCAATTATTATCATTTAGCTCTGCAAAGCTTTCCATGGCTAACACAGTAAATTTAAATAAAGCTCTCTTTGTCTCCTTCAAATAA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
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Fusion Protein Sequence for TMPRSS2_TMEFF2 |
| In-frame Fusion Protein Sequences. |
>TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931 length=358nt MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000392314_42852402_192863931 length=249nt MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIGRQWIHR >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931 length=402nt MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931 length=386nt MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI |
| N-Truncated Protein (5UTR-3CDS) Sequences |
| C-Truncated Protein (5CDS-3UTR) Sequences |
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Personalized Fusion Protein Sequence for TMPRSS2_TMEFF2 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.H280N_358_H292N length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCENSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.E267K;p.E279K_358_E279K;E291K length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPKHYNGFCMHGKCKHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.G313C_358_G325C length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPCPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D198Y_358_D210Y length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASYGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.G225D_358_G237D length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLDRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D198V_358_D210V length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASVGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.P314T_358_P326T length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGTVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S237F_358_S249F length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKFEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.F272L_358_F284L length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S201P;p.P314S_358_S213P;P326S length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKPYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGSVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S212L_358_S224L length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D185A_358_D197A length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIACSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.M284T_358_M296T length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINTQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.F317C_358_F329C length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRCQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S223Y_358_S235Y length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D304H_358_D316H length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKHYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D185G;p.H262R_358_D197G;H274R length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIGCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHRIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.A196T_358_A208T length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D246E_358_D258E length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTEYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S212L;p.E220K_358_S224L;E232K length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D203N_358_D215N length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.M284V_358_M296V length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINVQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.K303R_358_K315R length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKRDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S212L_358_S224L length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S212L_358_S224L length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S306N_358_S318N length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYNVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.F272L_358_F284L length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.E256D_358_E268D length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEDSAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.R226Q_358_R238Q length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGQCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.G276W_358_G288W length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHWKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.R316Q_358_R328Q length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVQFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D304N_358_D316N length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKNYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S223Y_358_S235Y length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S201A_358_S213A length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKAYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.D203N_358_D215N length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.E220K_358_E232K length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.S288T_358_S300T length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPT CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.G327R_358_G339R length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIRTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.E220K_358_E232K length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.V310I_358_V322I length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYIVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.M284I_358_M296I length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINIQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.C186S_358_C198S length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDSSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.A196T_358_A208T length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.G199E_358_G211E length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDEKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000272771_42852402_192863931_3-gene_p.A251V;p.H275Y_358_A263V;H287Y length=358AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENVNKLEESAREHHIPCPEHYNGFCMYGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000332149_ENST00000392314_42852402_192863931_5-gene_p.N192S_249_N192S length=249AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKSNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIGRQWIHR >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.H280N_402_H336N length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCENSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.E267K;p.E279K_402_E323K;E335K length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPKHYNGFCMHGKCKHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.G313C_402_G369C length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPCPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D198Y_402_D254Y length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASYGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.G225D_402_G281D length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLDRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D198V_402_D254V length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASVGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.P314T_402_P370T length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGTVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S237F_402_S293F length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKFEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.F272L_402_F328L length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S201P;p.P314S_402_S257P;P370S length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKPYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGSVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S212L_402_S268L length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D185A_402_D241A length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIACSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.M284T_402_M340T length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINTQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.F317C_402_F373C length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRCQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S223Y_402_S279Y length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D304H_402_D360H length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKHYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D185G;p.H262R_402_D241G;H318R length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIGCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHRIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.A196T_402_A252T length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D246E_402_D302E length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TEYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S212L;p.E220K_402_S268L;E276K length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D203N_402_D259N length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.M284V_402_M340V length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINVQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.K303R_402_K359R length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKRDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S212L_402_S268L length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S212L_402_S268L length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S306N_402_S362N length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYNVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.F272L_402_F328L length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.E256D_402_E312D length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEDSAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.R226Q_402_R282Q length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGQCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.G276W_402_G332W length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHWKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.R316Q_402_R372Q length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVQFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D304N_402_D360N length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKNYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S223Y_402_S279Y length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S201A_402_S257A length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKAYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.D203N_402_D259N length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.E220K_402_E276K length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.S288T_402_S344T length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPTCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.G327R_402_G383R length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIRTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.E220K_402_E276K length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.V310I_402_V366I length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYIVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.M284I_402_M340I length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINIQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.C186S_402_C242S length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDSSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.A196T_402_A252T length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.G199E_402_G255E length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDEKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000272771_42852402_192863931_3-gene_p.A251V;p.H275Y_402_A307V;H331Y length=402AA MGAWDPPMPPAPPGGESGCEERGAAGHIEHSRYLSLLDAVDNSKMALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLW KFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYAR TDYAENVNKLEESAREHHIPCPEHYNGFCMYGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRAKL >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.H280N_386_H292N length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCENSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.E267K;p.E279K_386_E279K;E291K length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPKHYNGFCMHGKCKHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.G313C_386_G325C length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPCPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D198Y_386_D210Y length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASYGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.G225D_386_G237D length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLDRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D198V_386_D210V length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASVGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.P314T_386_P326T length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGTVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S237F_386_S249F length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKFEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.F272L_386_F284L length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S201P;p.P314S_386_S213P;P326S length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKPYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGSVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S212L_386_S224L length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D185A_386_D197A length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIACSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.M284T_386_M296T length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINTQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.F317C_386_F329C length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRCQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S223Y_386_S235Y length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D304H_386_D316H length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKHYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.T371M_386_T383M length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASMRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D185G;p.H262R_386_D197G;H274R length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIGCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHRIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.A196T_386_A208T length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D246E_386_D258E length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTEYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.A369V_386_A381V length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRVSTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S212L;p.E220K_386_S224L;E232K length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D203N_386_D215N length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.M284V_386_M296V length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINVQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.K303R_386_K315R length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKRDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S212L_386_S224L length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S212L_386_S224L length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEALCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S306N_386_S318N length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYNVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.F272L_386_F284L length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGLCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.E256D_386_E268D length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEDSAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.R226Q_386_R238Q length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGQCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.G276W_386_G288W length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHWKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.R316Q;p.R350I_386_R328Q;R362I length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVQFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNIIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.R350I_386_R362I length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNIIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D304N_386_D316N length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKNYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S223Y_386_S235Y length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMYLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S201A_386_S213A length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKAYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.D203N_386_D215N length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYNNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.E220K_386_E232K length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.R350K_386_R362K length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNKIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.S288T_386_S300T length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPT CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.G327R_386_G339R length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIRTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.E220K_386_E232K length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIKVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.V310I_386_V322I length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYIVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.M284I_386_M296I length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINIQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.C186S_386_C198S length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDSSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.A196T_386_A208T length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCTSDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.G199E_386_G211E length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDEKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI >TMPRSS2_TMEFF2_ENST00000398585_ENST00000392314_42852402_192863931_3-gene_p.A251V;p.H275Y_386_A263V;H287Y length=386AA MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVR LYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENVNKLEESAREHHIPCPEHYNGFCMYGKCEHSINMQEPS CRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-44-6778-01A | 3-gene | p.H280N | 358 | H292N |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-4Z-AA7R-01A | 3-gene | p.E267K;p.E279K | 358 | E279K;E291K |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-50-5930-01A | 3-gene | p.G313C | 358 | G325C |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-50-5933-01A | 3-gene | p.D198Y | 358 | D210Y |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-51-6867-01A | 3-gene | p.G225D | 358 | G237D |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-69-7974-01A | 3-gene | p.D198V | 358 | D210V |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-95-7043-01A | 3-gene | p.P314T | 358 | P326T |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-A5-A0G1-01A | 3-gene | p.S237F | 358 | S249F |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AA-3984-01A | 3-gene | p.F272L | 358 | F284L |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AG-A002-01A | 3-gene | p.S201P;p.P314S | 358 | S213P;P326S |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AJ-A3EL-01A | 3-gene | p.S212L | 358 | S224L |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AN-A046-01A | 3-gene | p.D185A | 358 | D197A |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AN-A0XU-01A | 3-gene | p.M284T | 358 | M296T |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AX-A05Z-01A | 3-gene | p.F317C | 358 | F329C |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-AX-A2HC-01A | 3-gene | p.S223Y | 358 | S235Y |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-B0-5115-01A | 3-gene | p.D304H | 358 | D316H |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-B5-A3FA-01A | 3-gene | p.D185G;p.H262R | 358 | D197G;H274R |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-BG-A221-01A | 3-gene | p.A196T | 358 | A208T |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-BS-A0TC-01A | 3-gene | p.D246E | 358 | D258E |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-D3-A8GM-06A | 3-gene | p.S212L;p.E220K | 358 | S224L;E232K |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-D3-A8GQ-06A | 3-gene | p.D203N | 358 | D215N |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-DA-A960-01A | 3-gene | p.M284V | 358 | M296V |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-DD-AADS-01A | 3-gene | p.K303R | 358 | K315R |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-DK-A6AW-01A | 3-gene | p.S212L | 358 | S224L |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-DU-6392-01A | 3-gene | p.S212L | 358 | S224L |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EE-A29D-06A | 3-gene | p.S306N | 358 | S318N |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EE-A29X-06A | 3-gene | p.F272L | 358 | F284L |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EE-A2GI-06A | 3-gene | p.E256D | 358 | E268D |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EE-A2MI-06A | 3-gene | p.R226Q | 358 | R238Q |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EE-A3AC-06A | 3-gene | p.G276W | 358 | G288W |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EI-6917-01A | 3-gene | p.R316Q | 358 | R328Q |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-ER-A195-06A | 3-gene | p.D304N | 358 | D316N |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-EY-A1G8-01A | 3-gene | p.S223Y | 358 | S235Y |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-F5-6814-01A | 3-gene | p.S201A | 358 | S213A |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-FD-A3SN-01A | 3-gene | p.D203N | 358 | D215N |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-FS-A1Z3-06A | 3-gene | p.E220K | 358 | E232K |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-G2-AA3F-01A | 3-gene | p.S288T | 358 | S300T |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-GF-A4EO-06A | 3-gene | p.G327R | 358 | G339R |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-GF-A6C9-06A | 3-gene | p.E220K | 358 | E232K |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-HU-A4H4-01A | 3-gene | p.V310I | 358 | V322I |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-L7-A56G-01A | 3-gene | p.M284I | 358 | M296I |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-OR-A5KB-01A | 3-gene | p.C186S | 358 | C198S |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-VQ-AA6J-01A | 3-gene | p.A196T | 358 | A208T |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-W3-AA1V-06B | 3-gene | p.G199E | 358 | G211E |
| ENST00000332149_ENST00000272771_42852402_192863931 | TCGA-WS-AB45-01A | 3-gene | p.A251V;p.H275Y | 358 | A263V;H287Y |
| ENST00000332149_ENST00000392314_42852402_192863931 | TCGA-EE-A3JI-06A | 5-gene | p.N192S | 249 | N192S |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-44-6778-01A | 3-gene | p.H280N | 402 | H336N |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-4Z-AA7R-01A | 3-gene | p.E267K;p.E279K | 402 | E323K;E335K |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-50-5930-01A | 3-gene | p.G313C | 402 | G369C |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-50-5933-01A | 3-gene | p.D198Y | 402 | D254Y |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-51-6867-01A | 3-gene | p.G225D | 402 | G281D |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-69-7974-01A | 3-gene | p.D198V | 402 | D254V |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-95-7043-01A | 3-gene | p.P314T | 402 | P370T |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-A5-A0G1-01A | 3-gene | p.S237F | 402 | S293F |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AA-3984-01A | 3-gene | p.F272L | 402 | F328L |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AG-A002-01A | 3-gene | p.S201P;p.P314S | 402 | S257P;P370S |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AJ-A3EL-01A | 3-gene | p.S212L | 402 | S268L |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AN-A046-01A | 3-gene | p.D185A | 402 | D241A |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AN-A0XU-01A | 3-gene | p.M284T | 402 | M340T |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AX-A05Z-01A | 3-gene | p.F317C | 402 | F373C |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-AX-A2HC-01A | 3-gene | p.S223Y | 402 | S279Y |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-B0-5115-01A | 3-gene | p.D304H | 402 | D360H |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-B5-A3FA-01A | 3-gene | p.D185G;p.H262R | 402 | D241G;H318R |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-BG-A221-01A | 3-gene | p.A196T | 402 | A252T |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-BS-A0TC-01A | 3-gene | p.D246E | 402 | D302E |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-D3-A8GM-06A | 3-gene | p.S212L;p.E220K | 402 | S268L;E276K |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-D3-A8GQ-06A | 3-gene | p.D203N | 402 | D259N |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-DA-A960-01A | 3-gene | p.M284V | 402 | M340V |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-DD-AADS-01A | 3-gene | p.K303R | 402 | K359R |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-DK-A6AW-01A | 3-gene | p.S212L | 402 | S268L |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-DU-6392-01A | 3-gene | p.S212L | 402 | S268L |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EE-A29D-06A | 3-gene | p.S306N | 402 | S362N |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EE-A29X-06A | 3-gene | p.F272L | 402 | F328L |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EE-A2GI-06A | 3-gene | p.E256D | 402 | E312D |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EE-A2MI-06A | 3-gene | p.R226Q | 402 | R282Q |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EE-A3AC-06A | 3-gene | p.G276W | 402 | G332W |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EI-6917-01A | 3-gene | p.R316Q | 402 | R372Q |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-ER-A195-06A | 3-gene | p.D304N | 402 | D360N |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-EY-A1G8-01A | 3-gene | p.S223Y | 402 | S279Y |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-F5-6814-01A | 3-gene | p.S201A | 402 | S257A |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-FD-A3SN-01A | 3-gene | p.D203N | 402 | D259N |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-FS-A1Z3-06A | 3-gene | p.E220K | 402 | E276K |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-G2-AA3F-01A | 3-gene | p.S288T | 402 | S344T |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-GF-A4EO-06A | 3-gene | p.G327R | 402 | G383R |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-GF-A6C9-06A | 3-gene | p.E220K | 402 | E276K |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-HU-A4H4-01A | 3-gene | p.V310I | 402 | V366I |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-L7-A56G-01A | 3-gene | p.M284I | 402 | M340I |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-OR-A5KB-01A | 3-gene | p.C186S | 402 | C242S |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-VQ-AA6J-01A | 3-gene | p.A196T | 402 | A252T |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-W3-AA1V-06B | 3-gene | p.G199E | 402 | G255E |
| ENST00000398585_ENST00000272771_42852402_192863931 | TCGA-WS-AB45-01A | 3-gene | p.A251V;p.H275Y | 402 | A307V;H331Y |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-44-6778-01A | 3-gene | p.H280N | 386 | H292N |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-4Z-AA7R-01A | 3-gene | p.E267K;p.E279K | 386 | E279K;E291K |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-50-5930-01A | 3-gene | p.G313C | 386 | G325C |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-50-5933-01A | 3-gene | p.D198Y | 386 | D210Y |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-51-6867-01A | 3-gene | p.G225D | 386 | G237D |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-69-7974-01A | 3-gene | p.D198V | 386 | D210V |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-95-7043-01A | 3-gene | p.P314T | 386 | P326T |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-A5-A0G1-01A | 3-gene | p.S237F | 386 | S249F |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AA-3984-01A | 3-gene | p.F272L | 386 | F284L |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AG-A002-01A | 3-gene | p.S201P;p.P314S | 386 | S213P;P326S |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AJ-A3EL-01A | 3-gene | p.S212L | 386 | S224L |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AN-A046-01A | 3-gene | p.D185A | 386 | D197A |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AN-A0XU-01A | 3-gene | p.M284T | 386 | M296T |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AX-A05Z-01A | 3-gene | p.F317C | 386 | F329C |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-AX-A2HC-01A | 3-gene | p.S223Y | 386 | S235Y |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-B0-5115-01A | 3-gene | p.D304H | 386 | D316H |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-B5-A1MR-01A | 3-gene | p.T371M | 386 | T383M |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-B5-A3FA-01A | 3-gene | p.D185G;p.H262R | 386 | D197G;H274R |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-BG-A221-01A | 3-gene | p.A196T | 386 | A208T |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-BS-A0TC-01A | 3-gene | p.D246E | 386 | D258E |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-CM-4746-01A | 3-gene | p.A369V | 386 | A381V |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-D3-A8GM-06A | 3-gene | p.S212L;p.E220K | 386 | S224L;E232K |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-D3-A8GQ-06A | 3-gene | p.D203N | 386 | D215N |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-DA-A960-01A | 3-gene | p.M284V | 386 | M296V |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-DD-AADS-01A | 3-gene | p.K303R | 386 | K315R |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-DK-A6AW-01A | 3-gene | p.S212L | 386 | S224L |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-DU-6392-01A | 3-gene | p.S212L | 386 | S224L |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EE-A29D-06A | 3-gene | p.S306N | 386 | S318N |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EE-A29X-06A | 3-gene | p.F272L | 386 | F284L |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EE-A2GI-06A | 3-gene | p.E256D | 386 | E268D |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EE-A2MI-06A | 3-gene | p.R226Q | 386 | R238Q |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EE-A3AC-06A | 3-gene | p.G276W | 386 | G288W |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EI-6917-01A | 3-gene | p.R316Q;p.R350I | 386 | R328Q;R362I |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EO-A3AV-01A | 3-gene | p.R350I | 386 | R362I |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-ER-A195-06A | 3-gene | p.D304N | 386 | D316N |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-EY-A1G8-01A | 3-gene | p.S223Y | 386 | S235Y |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-F5-6814-01A | 3-gene | p.S201A | 386 | S213A |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-FD-A3SN-01A | 3-gene | p.D203N | 386 | D215N |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-FS-A1Z3-06A | 3-gene | p.E220K | 386 | E232K |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-FS-A1ZZ-06A | 3-gene | p.R350K | 386 | R362K |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-G2-AA3F-01A | 3-gene | p.S288T | 386 | S300T |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-GF-A4EO-06A | 3-gene | p.G327R | 386 | G339R |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-GF-A6C9-06A | 3-gene | p.E220K | 386 | E232K |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-HU-A4H4-01A | 3-gene | p.V310I | 386 | V322I |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-L7-A56G-01A | 3-gene | p.M284I | 386 | M296I |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-OR-A5KB-01A | 3-gene | p.C186S | 386 | C198S |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-VQ-AA6J-01A | 3-gene | p.A196T | 386 | A208T |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-W3-AA1V-06B | 3-gene | p.G199E | 386 | G211E |
| ENST00000398585_ENST00000392314_42852402_192863931 | TCGA-WS-AB45-01A | 3-gene | p.A251V;p.H275Y | 386 | A263V;H287Y |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
Top |
Fusion Gene Exprssed Samples for TMPRSS2_TMEFF2 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | PRAD | TCGA-KK-A59Y-01A | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863934 | - | |
| ChimerDB | PRAD | TCGA-KK-A59Y | TMPRSS2 | chr21 | 42852402 | - | TMEFF2 | chr2 | 192863934 | - | |
| WashU | PRAD | TCGA-KK-A59Y-01A | TMPRSS2 | chr21 | 42852403 | - | TMEFF2 | chr2 | 192863934 | - | |
| cBioPortal | PRAD_TCGA_PAN_CAN_ATLAS_2018 | PRAD | TCGA-KK-A59Y-01 | TMPRSS2 | chr21 | 41480476 | TMEFF2 | chr2 | 191999208 |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
Top |
Related Drugs for TMPRSS2_TMEFF2 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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