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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SPAG16-CACHD1 (FusionGDB2 ID:HG79582TG57685)

Fusion Gene Summary for SPAG16-CACHD1

check button Fusion gene summary
Fusion gene informationFusion gene name: SPAG16-CACHD1
Fusion gene ID: hg79582tg57685
HgeneTgene
Gene symbol

SPAG16

CACHD1

Gene ID

79582

57685

Gene namesperm associated antigen 16cache domain containing 1
SynonymsPF20|WDR29-
Cytomap('SPAG16')('CACHD1')

2q34

1p31.3

Type of geneprotein-codingprotein-coding
Descriptionsperm-associated antigen 16 proteinWD repeat domain 29pf20 protein homologsperm-associated WD repeat proteinVWFA and cache domain-containing protein 1cache domain-containing protein 1von Willebrand factor type A and cache domain containing 1
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000414961, ENST00000272898, 
ENST00000331683, ENST00000374309, 
ENST00000413312, ENST00000432529, 
ENST00000447990, 
Fusion gene scores* DoF score6 X 5 X 4=12015 X 11 X 7=1155
# samples 615
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1155*10)=-2.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SPAG16 [Title/Abstract] AND CACHD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSPAG16(214162081)-CACHD1(65016277), # samples:1
Anticipated loss of major functional domain due to fusion event.SPAG16-CACHD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SPAG16-CACHD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across SPAG16 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CACHD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-7670-01ASPAG16chr2

214162081

+CACHD1chr1

65016277

+


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Fusion Gene ORF analysis for SPAG16-CACHD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000414961ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
3UTR-3CDSENST00000414961ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
3UTR-3UTRENST00000414961ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000272898ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000331683ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000374309ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000413312ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000432529ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
5CDS-3UTRENST00000447990ENST00000495994SPAG16chr2

214162081

+CACHD1chr1

65016277

+
Frame-shiftENST00000374309ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
Frame-shiftENST00000374309ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000272898ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000272898ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000331683ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000331683ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000413312ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000413312ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000432529ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000432529ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000447990ENST00000290039SPAG16chr2

214162081

+CACHD1chr1

65016277

+
In-frameENST00000447990ENST00000371073SPAG16chr2

214162081

+CACHD1chr1

65016277

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331683SPAG16chr2214162081+ENST00000371073CACHD1chr165016277+54983745640001314
ENST00000331683SPAG16chr2214162081+ENST00000290039CACHD1chr165016277+54983745640001314
ENST00000432529SPAG16chr2214162081+ENST00000371073CACHD1chr165016277+54953715339971314
ENST00000432529SPAG16chr2214162081+ENST00000290039CACHD1chr165016277+54953715339971314
ENST00000413312SPAG16chr2214162081+ENST00000371073CACHD1chr165016277+555643218040581292
ENST00000413312SPAG16chr2214162081+ENST00000290039CACHD1chr165016277+555643218040581292
ENST00000272898SPAG16chr2214162081+ENST00000371073CACHD1chr165016277+5407283439091301
ENST00000272898SPAG16chr2214162081+ENST00000290039CACHD1chr165016277+5407283439091301
ENST00000447990SPAG16chr2214162081+ENST00000371073CACHD1chr165016277+5406282339081301
ENST00000447990SPAG16chr2214162081+ENST00000290039CACHD1chr165016277+5406282339081301

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331683ENST00000371073SPAG16chr2214162081+CACHD1chr165016277+0.0001134580.9998865
ENST00000331683ENST00000290039SPAG16chr2214162081+CACHD1chr165016277+0.0001134580.9998865
ENST00000432529ENST00000371073SPAG16chr2214162081+CACHD1chr165016277+0.0001131180.9998869
ENST00000432529ENST00000290039SPAG16chr2214162081+CACHD1chr165016277+0.0001131180.9998869
ENST00000413312ENST00000371073SPAG16chr2214162081+CACHD1chr165016277+0.0001157730.99988425
ENST00000413312ENST00000290039SPAG16chr2214162081+CACHD1chr165016277+0.0001157730.99988425
ENST00000272898ENST00000371073SPAG16chr2214162081+CACHD1chr165016277+0.000106510.9998934
ENST00000272898ENST00000290039SPAG16chr2214162081+CACHD1chr165016277+0.000106510.9998934
ENST00000447990ENST00000371073SPAG16chr2214162081+CACHD1chr165016277+0.0001067860.9998932
ENST00000447990ENST00000290039SPAG16chr2214162081+CACHD1chr165016277+0.0001067860.9998932

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Fusion Genomic Features for SPAG16-CACHD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SPAG16chr2214162081+CACHD1chr165016276+4.17E-101
SPAG16chr2214162081+CACHD1chr165016276+4.17E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SPAG16-CACHD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:214162081/chr1:65016277)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCACHD1chr2:214162081chr1:65016277ENST000003710730271243_1260661275.0Compositional biasNote=His-rich
TgeneCACHD1chr2:214162081chr1:65016277ENST00000371073027943_982661275.0Compositional biasNote=Cys-rich
TgeneCACHD1chr2:214162081chr1:65016277ENST00000371073027228_443661275.0DomainVWFA
TgeneCACHD1chr2:214162081chr1:65016277ENST00000371073027453_532661275.0DomainNote=Cache 1
TgeneCACHD1chr2:214162081chr1:65016277ENST00000371073027772_853661275.0DomainNote=Cache 2
TgeneCACHD1chr2:214162081chr1:65016277ENST000003710730271117_1274661275.0Topological domainCytoplasmic
TgeneCACHD1chr2:214162081chr1:65016277ENST000003710730271096_1116661275.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310152_26793348.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316152_26793632.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27152_26762252.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35152_26793184.0Coiled coilOntology_term=ECO:0000255
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310350_38993348.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310392_43193348.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310434_47393348.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310476_51593348.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310518_55793348.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310560_60093348.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr1:65016277ENST00000272898+310601_63093348.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316350_38993632.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316392_43193632.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316434_47393632.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316476_51593632.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316518_55793632.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316560_60093632.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr1:65016277ENST00000331683+316601_63093632.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27350_38962252.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27392_43162252.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27434_47362252.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27476_51562252.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27518_55762252.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27560_60062252.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr1:65016277ENST00000413312+27601_63062252.0RepeatNote=WD 7
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35350_38993184.0RepeatNote=WD 1
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35392_43193184.0RepeatNote=WD 2
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35434_47393184.0RepeatNote=WD 3
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35476_51593184.0RepeatNote=WD 4
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35518_55793184.0RepeatNote=WD 5
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35560_60093184.0RepeatNote=WD 6
HgeneSPAG16chr2:214162081chr1:65016277ENST00000432529+35601_63093184.0RepeatNote=WD 7
TgeneCACHD1chr2:214162081chr1:65016277ENST0000037107302736_1095661275.0Topological domainExtracellular


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Fusion Gene Sequence for SPAG16-CACHD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>85418_85418_1_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000272898_CACHD1_chr1_65016277_ENST00000290039_length(transcript)=5407nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAAT
CCGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCT
AACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTG
TGATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCC
TGGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACA
CCGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACAC
TCAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATAC
CGTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAG
CAGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAA
GTTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCT
CCAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAA
AGAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAG
CATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGT
CTTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAAT
TGTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGA
CAAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAA
TATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTC
TTGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCT
GTGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCT
GGATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTT
TTCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCAT
TGCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAG
TAGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATT
TGATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGC
TGGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTT
CACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGA
GGACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCC
CCTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTA
TAAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAAC
CAACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCA
CCGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCG
AAACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAG
CAGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCT
GGACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGG
TGATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCT
GGCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTC
CAACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCAT
CGAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCC
ACAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGA
TACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACA
GGCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTT
CTGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGC
CTGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCC
TGATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCA
GAGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACAT
GCAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTC
TAAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGA
AAGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTAT
TTAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACA
TCTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATG
TTTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGG
AGGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTT
TTCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATC
CACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTA
CAGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTC
CGTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCA
GTACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATG

>85418_85418_1_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000272898_CACHD1_chr1_65016277_ENST00000290039_length(amino acids)=1301AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCD
RLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQ
LQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKF
QANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSM
MVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDK
GYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILC
IVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIA
NPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAG
YVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPL
VANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHR
MEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLD
KPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSN
LENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDT

--------------------------------------------------------------
>85418_85418_2_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000272898_CACHD1_chr1_65016277_ENST00000371073_length(transcript)=5407nt_BP=283nt
AGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGC
GAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATA
TGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGA
TACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAAT
CCGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCT
AACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTG
TGATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCC
TGGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACA
CCGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACAC
TCAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATAC
CGTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAG
CAGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAA
GTTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCT
CCAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAA
AGAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAG
CATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGT
CTTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAAT
TGTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGA
CAAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAA
TATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTC
TTGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCT
GTGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCT
GGATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTT
TTCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCAT
TGCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAG
TAGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATT
TGATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGC
TGGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTT
CACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGA
GGACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCC
CCTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTA
TAAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAAC
CAACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCA
CCGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCG
AAACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAG
CAGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCT
GGACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGG
TGATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCT
GGCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTC
CAACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCAT
CGAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCC
ACAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGA
TACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACA
GGCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTT
CTGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGC
CTGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCC
TGATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCA
GAGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACAT
GCAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTC
TAAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGA
AAGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTAT
TTAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACA
TCTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATG
TTTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGG
AGGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTT
TTCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATC
CACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTA
CAGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTC
CGTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCA
GTACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATG

>85418_85418_2_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000272898_CACHD1_chr1_65016277_ENST00000371073_length(amino acids)=1301AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCD
RLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQ
LQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKF
QANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSM
MVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDK
GYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILC
IVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIA
NPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAG
YVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPL
VANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHR
MEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLD
KPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSN
LENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDT

--------------------------------------------------------------
>85418_85418_3_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000331683_CACHD1_chr1_65016277_ENST00000290039_length(transcript)=5498nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAA
TCCGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCC
TAACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTT
GTGATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACC
CTGGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAAC
ACCGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACA
CTCAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATA
CCGTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTA
GCAGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAA
AGTTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTC
TCCAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGA
AAGAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCA
GCATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCG
TCTTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAA
TTGTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACG
ACAAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAA
ATATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGT
CTTGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTC
TGTGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGC
TGGATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCT
TTTCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCA
TTGCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGA
GTAGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCAT
TTGATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAG
CTGGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACT
TCACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGG
AGGACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGC
CCCTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTT
ATAAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAA
CCAACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTC
ACCGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACC
GAAACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACA
GCAGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACC
TGGACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAG
GTGATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCC
TGGCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGT
CCAACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCA
TCGAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCC
CACAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGG
ATACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTAC
AGGCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGT
TCTGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTG
CCTGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGC
CTGATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCC
AGAGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACA
TGCAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCT
CTAAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGG
AAAGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTA
TTTAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACAC
ATCTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTAT
GTTTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGG
GAGGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGT
TTTCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTAT
CCACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATT
ACAGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCT
CCGTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGC
AGTACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAAT

>85418_85418_3_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000331683_CACHD1_chr1_65016277_ENST00000290039_length(amino acids)=1314AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDG
NFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIV
VILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKA
FQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGV
PDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQ
DSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSY
AWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEH
YTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLI
SLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHA
PVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCA
CSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCE
WCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMS
PLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGV

--------------------------------------------------------------
>85418_85418_4_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000331683_CACHD1_chr1_65016277_ENST00000371073_length(transcript)=5498nt_BP=374nt
CGCGAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGC
CAGAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACG
CGAGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAAT
ATGAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAG
ATACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAA
TCCGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCC
TAACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTT
GTGATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACC
CTGGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAAC
ACCGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACA
CTCAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATA
CCGTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTA
GCAGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAA
AGTTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTC
TCCAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGA
AAGAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCA
GCATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCG
TCTTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAA
TTGTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACG
ACAAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAA
ATATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGT
CTTGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTC
TGTGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGC
TGGATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCT
TTTCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCA
TTGCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGA
GTAGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCAT
TTGATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAG
CTGGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACT
TCACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGG
AGGACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGC
CCCTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTT
ATAAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAA
CCAACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTC
ACCGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACC
GAAACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACA
GCAGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACC
TGGACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAG
GTGATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCC
TGGCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGT
CCAACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCA
TCGAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCC
CACAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGG
ATACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTAC
AGGCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGT
TCTGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTG
CCTGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGC
CTGATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCC
AGAGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACA
TGCAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCT
CTAAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGG
AAAGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTA
TTTAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACAC
ATCTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTAT
GTTTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGG
GAGGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGT
TTTCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTAT
CCACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATT
ACAGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCT
CCGTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGC
AGTACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAAT

>85418_85418_4_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000331683_CACHD1_chr1_65016277_ENST00000371073_length(amino acids)=1314AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDG
NFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIV
VILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKA
FQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGV
PDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQ
DSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSY
AWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEH
YTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLI
SLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHA
PVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCA
CSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCE
WCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMS
PLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGV

--------------------------------------------------------------
>85418_85418_5_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000413312_CACHD1_chr1_65016277_ENST00000290039_length(transcript)=5556nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGCGGATATTCAACTCCTTT
GTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATCCGAGAGAAGTTCAACCGTTACTTGGATGTG
GTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTAACTGCAATTCAAGACTGCTGTACTATCCCA
CCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGTGATCGACTTTCTACTACTGTTAATAGCCGG
GCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCTGGAATTAAGTGGCAATATTTCAGTTCAGAA
GAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACACCGCAGTAGACCCATCTACGTCTCTACAGTC
CGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACTCAGCTTCAGATTGCCAAGGACGCTGCTCAG
GTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACCGTCCGGACTTGCTCACTAGACCAGTGCTAT
AAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGCAGCGTGAAGTCTTCAGACAGTCCTACCCAG
CACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAGTTCCAAGCAAATACAGACATGGTCATCATT
TACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTCCAAGTCATCAATGAAGAAAATAGCTTTCTA
AACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAAGAGCTGGCTTTTCTGAGGGATCTAGCTGAA
CAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGCATGATGGTGCTGAATCAGTTGAGCAACCTG
GAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTCTTCAGCCTGCCCTTCTCTGATGAGATGGGA
GATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATTGTAGGTGTGGACGTGAATCTGGCTTACATT
CTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGACAAAGGATATACACTTATGCACCCATCTCTT
ACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAATATTCCAAAATTTGAATTAGTTCGGCAAAAT
ATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCTTGGCACATAAACAAGCTGAGAGAAACTGGA
AAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTGTGTATTGTGGTGATACAACCAGAAATACCT
GTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTGGATCTCCTTGGCCAGCCCAGTGCTTGCCTC
CACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTTTCCTCCCCCTATGAGCACCTCAGCCAGCCA
GAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATTGCTAACCCGGGCCTCAAATTCTCTGTCAGA
AATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGTAGCCTGAACACTTACATTGTCCGCCGTTAC
ATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTTGATCCCACTAGGAGACAATGGTATCTCCAT
GCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCTGGTTATGTTGTGACAATCAGTCACACAATT
CATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTCACACTCAGATACTTCTACAAAGTTCTGATG
GACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAGGACAGGGGTTATCTGGTGGCGCACCCGACT
CTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCCCTGGTAGCAAATGATATCCTCAACCACCCC
AACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTATAAATTCAACACCAGCCTTGCGGGGGATTTG
ACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACCAACGCGTTTGTTGGCATTGTCAACGAAACC
TGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCACCGAATGGAACAAAATGAATGTGAATGTCCT
TGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGAAACCCCAGCTGCGAGGTCCACCAGGAGCCG
GTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGCAGGTGCAGTCAGAGGCTGGAAAGTGGGGAC
TGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTGGACAAACCCTACTGTGCCCCCCAGAAAGAA
TGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGTGATGAGGTGATCACATTAAACATGATTAAA
AGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTGGCGGTGTATGCCTACCGCCACCAGATTCAT
CGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCCAACCTGGAGAATGACAGAGATGAAAGGGAC
GACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATCGAACGACATGCACACAGTCCAGAAAGAAGG
CGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCACAGGAGGACAGTGAAAATCCTCCATGCAAC
AATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGATACCCCCCCTCAGACTGCTGCCCTACTAAGT
CACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAGGCGGCCGTCACGGTACACACTGTCGATGCA
GAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTCTGGAAAGAAAAAGAACCGGCTTAAAACCCA
CAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCCTGTCGACATGGTTAAAAACGAGAGAAACAA
CAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCTGATGAACAGACCTGCCATAACACTAATGGA
AGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAGAGGAATGTTCCAAAGAGCCAGAAGCATTCA
GCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATGCAGATACAAATGTGTGCATTGAAGATTTCG
CTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCTAAACGATGCATCTCAGAATTTCTAAGTAAA
GGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAAAGGAAACACAGGAGAAGTTTTCAGCAGTTG
CCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATTTAACTGATATCCCACTGCCCCACTCCACAA
AATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACATCTTTGTTTGTAATGCAGTATTCTTTCTCTG
TGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGTTTCTTATGACTTGTTTCCACTCCTCGTACA
ATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGAGGGTTGGATTTATTTTCCTTGTTTTAGAGA
CTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTTTCTAAATTGTGAAAGTCTGGTTCTTAATTA
AAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCCACCAAATTGCTTTGTGATTTATACAGGGAT
TAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTACAGTGATGTATTTTAGACTCACATTTTGTGA
TTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCCGTTTATATGTAGTTGGAAAAAATTCACTGA
ATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAGTACAGAAAGTAAACTATATATGTGCTATCA

>85418_85418_5_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000413312_CACHD1_chr1_65016277_ENST00000290039_length(amino acids)=1292AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILRIFNSF
VYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSR
AFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQ
VILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVII
YLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNL
ETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSL
TRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIP
VKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVR
NEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTI
HSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHP
NFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECP
CECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKE
CFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERD
DDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLS

--------------------------------------------------------------
>85418_85418_6_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000413312_CACHD1_chr1_65016277_ENST00000371073_length(transcript)=5556nt_BP=432nt
AGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAGAGATGGCTGCTCAGCGAGGGATGC
CCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGAGGGACACGGCGGACGCGGTGGCGG
CTGAGGGCGCCTACTACCTGGAACGTATCCTTCCCGTGGAGGCGCGGCCCGCTGCGCTGGCGGGTAATGGGTGTTGGGACGAAGGCGAGG
GCCTCCCACTGGCGGCGCCTTTTGAGCCTTGGGGCCACTCCGGAGGAGCCTCTGTTGGACTTCAAGATACCAGATGACAATTTTAGCATC
CCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATACTGAAATTTTGCGGATATTCAACTCCTTT
GTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATCCGAGAGAAGTTCAACCGTTACTTGGATGTG
GTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTAACTGCAATTCAAGACTGCTGTACTATCCCA
CCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGTGATCGACTTTCTACTACTGTTAATAGCCGG
GCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCTGGAATTAAGTGGCAATATTTCAGTTCAGAA
GAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACACCGCAGTAGACCCATCTACGTCTCTACAGTC
CGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACTCAGCTTCAGATTGCCAAGGACGCTGCTCAG
GTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACCGTCCGGACTTGCTCACTAGACCAGTGCTAT
AAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGCAGCGTGAAGTCTTCAGACAGTCCTACCCAG
CACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAGTTCCAAGCAAATACAGACATGGTCATCATT
TACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTCCAAGTCATCAATGAAGAAAATAGCTTTCTA
AACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAAGAGCTGGCTTTTCTGAGGGATCTAGCTGAA
CAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGCATGATGGTGCTGAATCAGTTGAGCAACCTG
GAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTCTTCAGCCTGCCCTTCTCTGATGAGATGGGA
GATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATTGTAGGTGTGGACGTGAATCTGGCTTACATT
CTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGACAAAGGATATACACTTATGCACCCATCTCTT
ACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAATATTCCAAAATTTGAATTAGTTCGGCAAAAT
ATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCTTGGCACATAAACAAGCTGAGAGAAACTGGA
AAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTGTGTATTGTGGTGATACAACCAGAAATACCT
GTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTGGATCTCCTTGGCCAGCCCAGTGCTTGCCTC
CACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTTTCCTCCCCCTATGAGCACCTCAGCCAGCCA
GAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATTGCTAACCCGGGCCTCAAATTCTCTGTCAGA
AATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGTAGCCTGAACACTTACATTGTCCGCCGTTAC
ATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTTGATCCCACTAGGAGACAATGGTATCTCCAT
GCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCTGGTTATGTTGTGACAATCAGTCACACAATT
CATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTCACACTCAGATACTTCTACAAAGTTCTGATG
GACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAGGACAGGGGTTATCTGGTGGCGCACCCGACT
CTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCCCTGGTAGCAAATGATATCCTCAACCACCCC
AACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTATAAATTCAACACCAGCCTTGCGGGGGATTTG
ACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACCAACGCGTTTGTTGGCATTGTCAACGAAACC
TGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCACCGAATGGAACAAAATGAATGTGAATGTCCT
TGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGAAACCCCAGCTGCGAGGTCCACCAGGAGCCG
GTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGCAGGTGCAGTCAGAGGCTGGAAAGTGGGGAC
TGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTGGACAAACCCTACTGTGCCCCCCAGAAAGAA
TGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGTGATGAGGTGATCACATTAAACATGATTAAA
AGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTGGCGGTGTATGCCTACCGCCACCAGATTCAT
CGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCCAACCTGGAGAATGACAGAGATGAAAGGGAC
GACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATCGAACGACATGCACACAGTCCAGAAAGAAGG
CGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCACAGGAGGACAGTGAAAATCCTCCATGCAAC
AATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGATACCCCCCCTCAGACTGCTGCCCTACTAAGT
CACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAGGCGGCCGTCACGGTACACACTGTCGATGCA
GAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTCTGGAAAGAAAAAGAACCGGCTTAAAACCCA
CAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCCTGTCGACATGGTTAAAAACGAGAGAAACAA
CAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCTGATGAACAGACCTGCCATAACACTAATGGA
AGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAGAGGAATGTTCCAAAGAGCCAGAAGCATTCA
GCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATGCAGATACAAATGTGTGCATTGAAGATTTCG
CTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCTAAACGATGCATCTCAGAATTTCTAAGTAAA
GGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAAAGGAAACACAGGAGAAGTTTTCAGCAGTTG
CCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATTTAACTGATATCCCACTGCCCCACTCCACAA
AATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACATCTTTGTTTGTAATGCAGTATTCTTTCTCTG
TGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGTTTCTTATGACTTGTTTCCACTCCTCGTACA
ATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGAGGGTTGGATTTATTTTCCTTGTTTTAGAGA
CTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTTTCTAAATTGTGAAAGTCTGGTTCTTAATTA
AAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCCACCAAATTGCTTTGTGATTTATACAGGGAT
TAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTACAGTGATGTATTTTAGACTCACATTTTGTGA
TTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCCGTTTATATGTAGTTGGAAAAAATTCACTGA
ATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAGTACAGAAAGTAAACTATATATGTGCTATCA

>85418_85418_6_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000413312_CACHD1_chr1_65016277_ENST00000371073_length(amino acids)=1292AA_BP=84
MRAPTTWNVSFPWRRGPLRWRVMGVGTKARASHWRRLLSLGATPEEPLLDFKIPDDNFSIPEGEEDLAKAIQMAQEQATDTEILRIFNSF
VYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSR
AFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQ
VILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVII
YLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNL
ETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSL
TRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIP
VKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVR
NEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTI
HSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHP
NFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECP
CECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKE
CFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERD
DDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLS

--------------------------------------------------------------
>85418_85418_7_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000432529_CACHD1_chr1_65016277_ENST00000290039_length(transcript)=5495nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATCC
GAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTAA
CTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGTG
ATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCTG
GAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACACC
GCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACTC
AGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACCG
TCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGCA
GCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAGT
TCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTCC
AAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAAG
AGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGCA
TGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTCT
TCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATTG
TAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGACA
AAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAATA
TTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCTT
GGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTGT
GTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTGG
ATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTTT
CCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATTG
CTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGTA
GCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTTG
ATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCTG
GTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTCA
CACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAGG
ACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCCC
TGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTATA
AATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACCA
ACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCACC
GAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGAA
ACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGCA
GGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTGG
ACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGTG
ATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTGG
CGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCCA
ACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATCG
AACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCAC
AGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGATA
CCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAGG
CGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTCT
GGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCCT
GTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCTG
ATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAGA
GGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATGC
AGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCTA
AACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAAA
GGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATTT
AACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACATC
TTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGTT
TCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGAG
GGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTTT
CTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCCA
CCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTACA
GTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCCG
TTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAGT
ACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATGGA

>85418_85418_7_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000432529_CACHD1_chr1_65016277_ENST00000290039_length(amino acids)=1314AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDG
NFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIV
VILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKA
FQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGV
PDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQ
DSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSY
AWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEH
YTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLI
SLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHA
PVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCA
CSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCE
WCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMS
PLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGV

--------------------------------------------------------------
>85418_85418_8_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000432529_CACHD1_chr1_65016277_ENST00000371073_length(transcript)=5495nt_BP=371nt
GAGAGCTCCCGGGGGCCGTTGGGTAGCGTCTTCGCTGTTGCCCTTAGGGACGGCTGTGGGCCTGCTGGGGGTGGGGGCCCGAAGCGCCAG
AGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCGA
GGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATATG
AAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGATA
CTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATCC
GAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTAA
CTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGTG
ATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCTG
GAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACACC
GCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACTC
AGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACCG
TCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGCA
GCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAGT
TCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTCC
AAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAAG
AGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGCA
TGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTCT
TCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATTG
TAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGACA
AAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAATA
TTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCTT
GGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTGT
GTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTGG
ATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTTT
CCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATTG
CTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGTA
GCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTTG
ATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCTG
GTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTCA
CACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAGG
ACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCCC
TGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTATA
AATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACCA
ACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCACC
GAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGAA
ACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGCA
GGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTGG
ACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGTG
ATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTGG
CGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCCA
ACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATCG
AACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCAC
AGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGATA
CCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAGG
CGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTCT
GGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCCT
GTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCTG
ATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAGA
GGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATGC
AGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCTA
AACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAAA
GGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATTT
AACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACATC
TTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGTT
TCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGAG
GGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTTT
CTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCCA
CCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTACA
GTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCCG
TTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAGT
ACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATGGA

>85418_85418_8_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000432529_CACHD1_chr1_65016277_ENST00000371073_length(amino acids)=1314AA_BP=106
MWACWGWGPEAPEMAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLA
KAIQMAQEQATDTEILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDG
NFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIV
VILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKA
FQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGV
PDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQ
DSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSY
AWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEH
YTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLI
SLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHA
PVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCA
CSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCE
WCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMS
PLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGV

--------------------------------------------------------------
>85418_85418_9_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000447990_CACHD1_chr1_65016277_ENST00000290039_length(transcript)=5406nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATC
CGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTA
ACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGT
GATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCT
GGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACAC
CGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACT
CAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACC
GTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGC
AGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAG
TTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTC
CAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAA
GAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGC
ATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTC
TTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATT
GTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGAC
AAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAAT
ATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCT
TGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTG
TGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTG
GATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTT
TCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATT
GCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGT
AGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTT
GATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCT
GGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTC
ACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAG
GACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCC
CTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTAT
AAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACC
AACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCAC
CGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGA
AACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGC
AGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTG
GACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGT
GATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTG
GCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCC
AACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATC
GAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCA
CAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGAT
ACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAG
GCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTC
TGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCC
TGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCT
GATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAG
AGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATG
CAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCT
AAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAA
AGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATT
TAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACAT
CTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGT
TTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGA
GGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTT
TCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCC
ACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTAC
AGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCC
GTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAG
TACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATGG

>85418_85418_9_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000447990_CACHD1_chr1_65016277_ENST00000290039_length(amino acids)=1301AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCD
RLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQ
LQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKF
QANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSM
MVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDK
GYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILC
IVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIA
NPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAG
YVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPL
VANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHR
MEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLD
KPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSN
LENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDT

--------------------------------------------------------------
>85418_85418_10_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000447990_CACHD1_chr1_65016277_ENST00000371073_length(transcript)=5406nt_BP=282nt
GAGATGGCTGCTCAGCGAGGGATGCCCAGCTCCGCCGTGAGGGTCCTGGAAGAGGCGTTGGGCATGGGTTTGACGGCAGCCGGGGACGCG
AGGGACACGGCGGACGCGGTGGCGGCTGAGGGCGCCTACTACCTGGAACAGGTCACCATAACTGAAGCATCTGAAGATGACTATGAATAT
GAAGAGATACCAGATGACAATTTTAGCATCCCAGAAGGTGAAGAAGATCTGGCAAAAGCAATTCAGATGGCCCAAGAACAGGCTACAGAT
ACTGAAATTTTGCGGATATTCAACTCCTTTGTTTACACTGAGAAAATCTCAAATGGAGAAAGTGAAGTACAGCAGCTAGCCAAAAAAATC
CGAGAGAAGTTCAACCGTTACTTGGATGTGGTCAATCGGAACAAGCAAGTTGTAGAAGCATCCTATACGGCTCACCTAACCTCTCCCCTA
ACTGCAATTCAAGACTGCTGTACTATCCCACCTTCCATGATGGAATTCGATGGGAACTTTAATACCAATGTGTCTAGAACAATTAGTTGT
GATCGACTTTCTACTACTGTTAATAGCCGGGCCTTCAATCCAGGACGAGACTTAAATTCAGTTCTTGCAGACAACCTGAAATCCAACCCT
GGAATTAAGTGGCAATATTTCAGTTCAGAAGAAGGAATTTTCACTGTTTTCCCAGCACACAAGTTCCGGTGTAAGGGCAGCTACGAACAC
CGCAGTAGACCCATCTACGTCTCTACAGTCCGGCCGCAGTCAAAGCACATAGTAGTGATTCTGGACCACGGGGCTTCAGTCACAGACACT
CAGCTTCAGATTGCCAAGGACGCTGCTCAGGTCATCCTCAGCGCCATCGATGAACATGACAAGATTTCTGTGTTAACTGTGGCAGATACC
GTCCGGACTTGCTCACTAGACCAGTGCTATAAGACCTTCTTGTCTCCAGCCACCAGTGAGACAAAAAGGAAAATGTCCACCTTTGTTAGC
AGCGTGAAGTCTTCAGACAGTCCTACCCAGCACGCAGTGGGATTCCAAAAGGCATTTCAGCTGATTCGAAGTACAAACAATAACACAAAG
TTCCAAGCAAATACAGACATGGTCATCATTTACCTGTCAGCTGGCATTACATCAAAGGACTCTTCGGAAGAAGATAAAAAAGCGACTCTC
CAAGTCATCAATGAAGAAAATAGCTTTCTAAACAACTCTGTAATGATTCTCACCTATGCCCTCATGAACGATGGGGTGACTGGTTTGAAA
GAGCTGGCTTTTCTGAGGGATCTAGCTGAACAGAATTCAGGGAAGTACGGTGTGCCAGACCGGATGGCCTTGCCTGTGATTAAGGGCAGC
ATGATGGTGCTGAATCAGTTGAGCAACCTGGAGACCACAGTGGGCAGGTTCTACACAAACCTTCCCAACCGGATGATTGATGAAGCCGTC
TTCAGCCTGCCCTTCTCTGATGAGATGGGAGATGGTTTGATAATGACTGTGAGTAAACCCTGTTATTTTGGAAACCTACTTCTGGGAATT
GTAGGTGTGGACGTGAATCTGGCTTACATTCTTGAAGACGTGACGTATTACCAAGACTCTTTGGCTTCCTATACTTTTCTCATAGACGAC
AAAGGATATACACTTATGCACCCATCTCTTACCAGGCCATATTTATTGTCAGAGCCCCCACTTCATACTGACATCATACATTATGAAAAT
ATTCCAAAATTTGAATTAGTTCGGCAAAATATCCTAAGCCTCCCTCTGGGCAGCCAGATTATCGCAGTCCCTGTGAACTCATCCCTGTCT
TGGCACATAAACAAGCTGAGAGAAACTGGAAAGGAAGCCTACAATGTTAGCTATGCCTGGAAGATGGTACAAGACACTTCCTTTATTCTG
TGTATTGTGGTGATACAACCAGAAATACCTGTGAAACAACTGAAGAACCTCAACACTGTTCCCAGCAGCAAGCTGCTGTACCACCGGCTG
GATCTCCTTGGCCAGCCCAGTGCTTGCCTCCACTTCAAACAGCTGGCAACCCTAGAAAGTCCCACCATCATGCTGTCTGCTGGCAGCTTT
TCCTCCCCCTATGAGCACCTCAGCCAGCCAGAGACAAAGCGCATGGTAGAGCACTACACCGCCTATCTCAGCGACAACACCCGCCTCATT
GCTAACCCGGGCCTCAAATTCTCTGTCAGAAATGAAGTAATGGCTACCAGCCACGTCACAGATGAATGGATGACACAAATGGAAATGAGT
AGCCTGAACACTTACATTGTCCGCCGTTACATAGCAACACCCAATGGCGTCCTCAGAATTTATCCTGGTTCCCTCATGGACAAAGCATTT
GATCCCACTAGGAGACAATGGTATCTCCATGCAGTAGCTAATCCAGGGTTGATTTCTTTGACTGGTCCTTACTTAGATGTTGGAGGAGCT
GGTTATGTTGTGACAATCAGTCACACAATTCATTCATCCAGTACACAGCTGTCTTCTGGGCACACTGTGGCTGTGATGGGCATTGACTTC
ACACTCAGATACTTCTACAAAGTTCTGATGGACCTATTACCTGTCTGTAACCAAGATGGTGGCAACAAAATAAGGTGCTTCATAATGGAG
GACAGGGGTTATCTGGTGGCGCACCCGACTCTCATCGACCCCAAAGGACATGCACCTGTGGAGCAGCAGCACATCACCCACAAGGAGCCC
CTGGTAGCAAATGATATCCTCAACCACCCCAACTTTGTAAAGAAAAACCTGTGCAACAGCTTCAGTGACAGAACGGTCCAGAGGTTTTAT
AAATTCAACACCAGCCTTGCGGGGGATTTGACGAACCTTGTGCATGGCAGCCACTGTTCCAAATACAGATTAGCAAGGATCCCAGGAACC
AACGCGTTTGTTGGCATTGTCAACGAAACCTGCGACTCTCTTGCCTTCTGTGCCTGCAGCATGGTGGACCGACTCTGTCTCAACTGTCAC
CGAATGGAACAAAATGAATGTGAATGTCCTTGTGAGTGCCCTCTAGAGGTCAATGAGTGCACTGGCAACCTCACCAATGCAGAGAACCGA
AACCCCAGCTGCGAGGTCCACCAGGAGCCGGTGACATACACAGCTATTGACCCTGGCCTGCAAGATGCTCTTCACCAGTGTGTCAACAGC
AGGTGCAGTCAGAGGCTGGAAAGTGGGGACTGTTTTGGGGTGCTGGATTGTGAATGGTGCATGGTGGACAGTGATGGAAAGACTCACCTG
GACAAACCCTACTGTGCCCCCCAGAAAGAATGCTTCGGGGGGATTGTGGGAGCCAAAAGTCCCTACGTTGATGACATGGGAGCAATAGGT
GATGAGGTGATCACATTAAACATGATTAAAAGCGCCCCTGTGGGTCCTGTGGCTGGAGGGATCATGGGATGCATCATGGTCTTGGTCCTG
GCGGTGTATGCCTACCGCCACCAGATTCATCGCCGGAGCCATCAGCATATGTCTCCTCTTGCTGCCCAAGAAATGTCAGTGCGTATGTCC
AACCTGGAGAATGACAGAGATGAAAGGGACGACGACAGCCACGAAGACAGAGGCATCATCAGCAACACTCGGTTTATAGCTGCGGTCATC
GAACGACATGCACACAGTCCAGAAAGAAGGCGCCGCTACTGGGGTCGATCAGGAACAGAAAGTGATCATGGTTACAGCACCATGAGCCCA
CAGGAGGACAGTGAAAATCCTCCATGCAACAATGACCCCTTGTCAGCCGGGGTCGATGTGGGAAACCATGATGAGGACTTAGACCTGGAT
ACCCCCCCTCAGACTGCTGCCCTACTAAGTCACAAGTTCCACCACTACCGGTCACACCACCCTACACTTCATCATAGCCACCACTTACAG
GCGGCCGTCACGGTACACACTGTCGATGCAGAATGCTAACAATCTCCTCACCTCCACGCCAAGATGAGATCTGGGAGCTACAGAATGTTC
TGGAAAGAAAAAGAACCGGCTTAAAACCCACAGCAAGAGACCTCCCTTGTGTTTGTGCTTTGTGCAGAGTTGTTTGAGTCATTTCCTGCC
TGTCGACATGGTTAAAAACGAGAGAAACAACAACACAGTCACATTTGTGAAGATGTGAGGCTGGTTCTGAAATGGAGGGGAAATAAGCCT
GATGAACAGACCTGCCATAACACTAATGGAAGGTAACAGAAGGCGAACCTCCAAACACAGAGACGGAACCTGCAAGTGAAGCTGAGCCAG
AGGAATGTTCCAAAGAGCCAGAAGCATTCAGCTCTCCTTAACTGGAAGAGAGAAAAATCTGCTCACCCAGAGACTGGAATGTGGCACATG
CAGATACAAATGTGTGCATTGAAGATTTCGCTTTGTTTCTTAGCGGTACCTGGATACCACAGTTGCTGTATGGAACTCATGTTATGCTCT
AAACGATGCATCTCAGAATTTCTAAGTAAAGGATTATTTTTCTACTATTTATTGAACTTTCAAACATTCTCAAACTTTGGGGAAAAGGAA
AGGAAACACAGGAGAAGTTTTCAGCAGTTGCCCCGAGCTGTTTTGTGTGTAATGAAGTGGTTCTTTGATTAAGGAGCTCTATTTCTTATT
TAACTGATATCCCACTGCCCCACTCCACAAAATAGGAAAATGAAGAAATCTTTCTCTCTGACTTGTTTACATCATTTCACGGAAACACAT
CTTTGTTTGTAATGCAGTATTCTTTCTCTGTGTTTGACAGAGATGGGGAGGGGCAGAGGAATTTAAGAGGTTTTAAAAGAAATGTTATGT
TTCTTATGACTTGTTTCCACTCCTCGTACAATGCTATTCTTAGGTTTCTACGAAACCTAATGTTAGAACCGCATCCTTTCAGCTAAGGGA
GGGTTGGATTTATTTTCCTTGTTTTAGAGACTACAAATTTTTAAATATCCCATTTTGACTGAGAATATTGACATATAAGGGAAGAAGTTT
TCTAAATTGTGAAAGTCTGGTTCTTAATTAAAGAATTTTTTTTTTAATATCACGGTTAAAAGCTGCTGCCAGTTAGCCAAGACATTATCC
ACCAAATTGCTTTGTGATTTATACAGGGATTAATCAAATCTGGCTACTATAACATGGGGCATTGTAACTTTAAAGTAGTGTTTTAATTAC
AGTGATGTATTTTAGACTCACATTTTGTGATTCAAATATGTTATAAAGGCATTCTTGCACCATGGTAAAGAATGTGTGTGGTAAATCTCC
GTTTATATGTAGTTGGAAAAAATTCACTGAATAATGTTTTAATGATAGGGTATTATGATACAATGTAAAAAACAATTGGTTCTTCAGCAG
TACAGAAAGTAAACTATATATGTGCTATCAGGAAACCCCTTCATACTGTGTATAAAATTGCAATCTAGTGAAATAAACCGTATGCAATGG

>85418_85418_10_SPAG16-CACHD1_SPAG16_chr2_214162081_ENST00000447990_CACHD1_chr1_65016277_ENST00000371073_length(amino acids)=1301AA_BP=93
MAAQRGMPSSAVRVLEEALGMGLTAAGDARDTADAVAAEGAYYLEQVTITEASEDDYEYEEIPDDNFSIPEGEEDLAKAIQMAQEQATDT
EILRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCD
RLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQ
LQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKF
QANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSM
MVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDK
GYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILC
IVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIA
NPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAG
YVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPL
VANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHR
MEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLD
KPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSN
LENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDT

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Fusion Gene PPI Analysis for SPAG16-CACHD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SPAG16-CACHD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SPAG16-CACHD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource