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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene Breakpoints

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness

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Fusion Genomic Features

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Fusion Gene ORF Annotations

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Fusion Protein Retained/Non-Retained Functional Features

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Fusion Transcript Sequences

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Fusion Protein Sequences

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Personalized Fusion Protein Sequences

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Fusion Gene Expressed Samples

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Related Drugs

Fusion gene:EFHD1_EIF4E2 (FusionGDB2 ID:HG80303TG9470)

Fusion Gene Summary for EFHD1_EIF4E2

check button Fusion gene summary
Fusion gene informationFusion gene name: EFHD1_EIF4E2
Fusion gene ID: hg80303tg9470
HgeneTgene
Gene symbol

EFHD1

EIF4E2

Gene ID

80303

9470

Gene nameEF-hand domain family member D1eukaryotic translation initiation factor 4E family member 2
SynonymsMST133|MSTP133|PP3051|SWS24E-LP|4EHP|EIF4EL3|IF4e|h4EHP
Cytomap

2q37.1

2q37.1

Type of geneprotein-codingprotein-coding
DescriptionEF-hand domain-containing protein D1EF-hand domain-containing protein 1swiprosin-2eukaryotic translation initiation factor 4E type 2eIF-4E type 2eIF4E-like cap-binding proteineIF4E-like protein 4E-LPeukaryotic translation initiation factor 4E homologous proteineukaryotic translation initiation factor 4E-like 3mRNA cap-binding pro
Modification date2024041120240411
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000264059, ENST00000409613, 
ENST00000409708, ENST00000410095, 
Fusion gene scores* DoF score* DoF score (Degree of Frequency) = # partners X # break points X # disease types
3 X 3 X 4=36		* DoF score (Degree of Frequency) = # partners X # break points X # disease types
5 X 15 X 7=525
# samples 9124
** MAII score** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(9/36*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(124/525*10)=1.23995079272075
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: EFHD1 [Title/Abstract] AND EIF4E2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEFHD1(233537153)-EIF4E2(233431538), # samples:1

check buttonFusion gene breakpoints across EFHD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across EIF4E2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Fusion Gene Breakpoints for EFHD1_EIF4E2


check button RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbp
EFHD1chr2233537153EIF4E2chr2233428957
EFHD1chr2233537153EIF4E2chr2233537153
EFHD1chr2233537153EIF4E2chr2233431539
EFHD1chr2232672443EIF4E2chr2232564247
EFHD1chr2232672443EIF4E2chr2232566829


check button DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbpSV type


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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for EFHD1_EIF4E2


check button To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.
* We have 10 tumorigenic mechanism categories of fusion genes as shown below.
Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand FusionsAberrant Chimeric Transcription Factor / Fusion Transcription Factor ActivityEpigenetic Reprogramming / Histone Modifier DysregulationChromatin Remodeling DysregulationCondensate-Driven Transcriptional Rewiring / LLPPromoter / Enhancer HijackingDominant-Negative AntagonismCell Cycle / Checkpoint Bypass / RNA Processing DysregulationSubcellular Mislocalization / Spatial DysregulationNuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneEIF4E2

GO:0035278

miRNA-mediated gene silencing by inhibition of translation

28487484

TgeneEIF4E2

GO:0045947

negative regulation of translational initiation

32726578|35878012

TgeneEIF4E2

GO:0060339

negative regulation of type I interferon-mediated signaling pathway

35878012

TgeneEIF4E2

GO:0072344

rescue of stalled ribosome

32726578


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Fusion Genomic Features for EFHD1_EIF4E2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EFHD1chr2233537153+EIF4E2chr2233428956+3.86e-101.00e+00
EFHD1chr2233537153+EIF4E2chr2233431538+1.89e-091.00e+00


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).
genomic feature

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Fusion Gene ORF Annotations for EFHD1_EIF4E2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000264059ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000264059ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000264059ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409613ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409613ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000409708ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000409708ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000258416EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409098EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409167EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409322EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409394EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409495EFHD1chr2

233537153

+EIF4E2chr2

233431538

+
In-frameENST00000410095ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233428956

+
In-frameENST00000410095ENST00000409514EFHD1chr2

233537153

+EIF4E2chr2

233431538

+

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score
ENST00000410095ENST00000258416EFHD1chr2233537153EIF4E2chr22334289566.22e-049.99e-01
ENST00000409708ENST00000258416EFHD1chr2233537153EIF4E2chr22334315383.49e-039.97e-01
ENST00000409708ENST00000409098EFHD1chr2233537153EIF4E2chr22334289561.23e-029.88e-01
ENST00000409708ENST00000409098EFHD1chr2233537153EIF4E2chr22334315381.71e-029.83e-01
ENST00000409708ENST00000409167EFHD1chr2233537153EIF4E2chr22334289569.76e-039.90e-01
ENST00000409708ENST00000409167EFHD1chr2233537153EIF4E2chr22334315382.71e-017.29e-01
ENST00000409708ENST00000409322EFHD1chr2233537153EIF4E2chr22334289562.91e-039.97e-01
ENST00000409708ENST00000409322EFHD1chr2233537153EIF4E2chr22334315382.68e-039.97e-01
ENST00000409708ENST00000409394EFHD1chr2233537153EIF4E2chr22334289562.19e-039.98e-01
ENST00000409708ENST00000409394EFHD1chr2233537153EIF4E2chr22334315382.14e-039.98e-01
ENST00000409708ENST00000409495EFHD1chr2233537153EIF4E2chr22334289563.72e-039.96e-01
ENST00000409708ENST00000409495EFHD1chr2233537153EIF4E2chr22334315384.03e-029.60e-01
ENST00000409708ENST00000409514EFHD1chr2233537153EIF4E2chr22334289561.28e-029.87e-01
ENST00000409708ENST00000409514EFHD1chr2233537153EIF4E2chr22334315381.79e-029.82e-01
ENST00000409708ENST00000258416EFHD1chr2233537153EIF4E2chr22334289563.51e-039.96e-01
ENST00000410095ENST00000258416EFHD1chr2233537153EIF4E2chr22334315385.45e-049.99e-01
ENST00000410095ENST00000409098EFHD1chr2233537153EIF4E2chr22334289561.22e-029.88e-01
ENST00000410095ENST00000409098EFHD1chr2233537153EIF4E2chr22334315381.73e-029.83e-01
ENST00000410095ENST00000409167EFHD1chr2233537153EIF4E2chr22334289566.53e-039.93e-01
ENST00000410095ENST00000409167EFHD1chr2233537153EIF4E2chr22334315381.77e-018.23e-01
ENST00000410095ENST00000409322EFHD1chr2233537153EIF4E2chr22334289564.60e-041.00e+00
ENST00000410095ENST00000409322EFHD1chr2233537153EIF4E2chr22334315383.84e-041.00e+00
ENST00000410095ENST00000409394EFHD1chr2233537153EIF4E2chr22334289562.55e-041.00e+00
ENST00000410095ENST00000409394EFHD1chr2233537153EIF4E2chr22334315381.89e-041.00e+00
ENST00000410095ENST00000409495EFHD1chr2233537153EIF4E2chr22334289568.68e-049.99e-01
ENST00000410095ENST00000409495EFHD1chr2233537153EIF4E2chr22334315386.58e-039.93e-01
ENST00000410095ENST00000409514EFHD1chr2233537153EIF4E2chr22334289561.26e-029.87e-01
ENST00000410095ENST00000409514EFHD1chr2233537153EIF4E2chr22334315381.80e-029.82e-01
ENST00000409613ENST00000258416EFHD1chr2233537153EIF4E2chr22334289565.76e-049.99e-01
ENST00000264059ENST00000258416EFHD1chr2233537153EIF4E2chr22334315381.46e-041.00e+00
ENST00000264059ENST00000409098EFHD1chr2233537153EIF4E2chr22334289561.32e-039.99e-01
ENST00000264059ENST00000409098EFHD1chr2233537153EIF4E2chr22334315381.63e-039.98e-01
ENST00000264059ENST00000409167EFHD1chr2233537153EIF4E2chr22334289567.91e-049.99e-01
ENST00000264059ENST00000409167EFHD1chr2233537153EIF4E2chr22334315389.29e-049.99e-01
ENST00000264059ENST00000409322EFHD1chr2233537153EIF4E2chr22334289561.23e-041.00e+00
ENST00000264059ENST00000409322EFHD1chr2233537153EIF4E2chr22334315381.33e-041.00e+00
ENST00000264059ENST00000409394EFHD1chr2233537153EIF4E2chr22334289561.30e-041.00e+00
ENST00000264059ENST00000409394EFHD1chr2233537153EIF4E2chr22334315381.41e-041.00e+00
ENST00000264059ENST00000409495EFHD1chr2233537153EIF4E2chr22334289562.78e-041.00e+00
ENST00000264059ENST00000409495EFHD1chr2233537153EIF4E2chr22334315383.11e-041.00e+00
ENST00000264059ENST00000409514EFHD1chr2233537153EIF4E2chr22334289561.38e-039.99e-01
ENST00000264059ENST00000409514EFHD1chr2233537153EIF4E2chr22334315381.68e-039.98e-01
ENST00000264059ENST00000258416EFHD1chr2233537153EIF4E2chr22334289561.34e-041.00e+00
ENST00000409613ENST00000258416EFHD1chr2233537153EIF4E2chr22334315383.25e-041.00e+00
ENST00000409613ENST00000409098EFHD1chr2233537153EIF4E2chr22334289561.20e-029.88e-01
ENST00000409613ENST00000409098EFHD1chr2233537153EIF4E2chr22334315381.06e-029.89e-01
ENST00000409613ENST00000409167EFHD1chr2233537153EIF4E2chr22334289566.58e-039.93e-01
ENST00000409613ENST00000409167EFHD1chr2233537153EIF4E2chr22334315381.20e-018.80e-01
ENST00000409613ENST00000409322EFHD1chr2233537153EIF4E2chr22334289564.46e-041.00e+00
ENST00000409613ENST00000409322EFHD1chr2233537153EIF4E2chr22334315382.30e-041.00e+00
ENST00000409613ENST00000409394EFHD1chr2233537153EIF4E2chr22334289562.54e-041.00e+00
ENST00000409613ENST00000409394EFHD1chr2233537153EIF4E2chr22334315381.37e-041.00e+00
ENST00000409613ENST00000409495EFHD1chr2233537153EIF4E2chr22334289561.11e-039.99e-01
ENST00000409613ENST00000409495EFHD1chr2233537153EIF4E2chr22334315387.48e-039.93e-01
ENST00000409613ENST00000409514EFHD1chr2233537153EIF4E2chr22334289561.23e-029.88e-01
ENST00000409613ENST00000409514EFHD1chr2233537153EIF4E2chr22334315381.08e-029.89e-01

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

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Fusion Protein Retained/Non-Retained Functional Features for EFHD1_EIF4E2

check buttonProtein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.
fgviewer annotation
- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).
EFHD1_EIF4E2_chr2-233537153_chr2-233428956.png
EFHD1_EIF4E2_chr2-233537153_chr2-233428956.png
EFHD1_EIF4E2_chr2-233537153_chr2-233431538.png
EFHD1_EIF4E2_chr2-233537153_chr2-233431538.png

- In-frame and retained protein feature among the 13 regional features (texts).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEFHD1chr2:233537153chr2:233428956ENST00000264059Q9BUP0341_18195.0240.0Compositional biasBasic and acidic residues
HgeneEFHD1chr2:233537153chr2:233431538ENST00000264059Q9BUP0341_18195.0240.0Compositional biasBasic and acidic residues
HgeneEFHD1chr2:233537153chr2:233428956ENST00000264059Q9BUP034126_161195.0240.0DomainEF-hand 2
HgeneEFHD1chr2:233537153chr2:233428956ENST00000264059Q9BUP03490_125195.0240.0DomainEF-hand 1
HgeneEFHD1chr2:233537153chr2:233431538ENST00000264059Q9BUP034126_161195.0240.0DomainEF-hand 2
HgeneEFHD1chr2:233537153chr2:233431538ENST00000264059Q9BUP03490_125195.0240.0DomainEF-hand 1
HgeneEFHD1chr2:233537153chr2:233428956ENST00000264059Q9BUP0341_53195.0240.0RegionDisordered
HgeneEFHD1chr2:233537153chr2:233431538ENST00000264059Q9BUP0341_53195.0240.0RegionDisordered
TgeneEIF4E2chr2:233537153chr2:233428956ENST00000258416O6057327150_15790.0246.0RegionEIF4EBP1/2/3 binding
TgeneEIF4E2chr2:233537153chr2:233428956ENST00000258416O605732795_9990.0246.0RegionEIF4EBP1/2/3 binding
TgeneEIF4E2chr2:233537153chr2:233431538ENST00000258416O6057337150_157125.0246.0RegionEIF4EBP1/2/3 binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEIF4E2chr2:233537153chr2:233428956ENST00000258416O60573271_3890.0246.0Compositional biasBasic and acidic residues
TgeneEIF4E2chr2:233537153chr2:233431538ENST00000258416O60573371_38125.0246.0Compositional biasBasic and acidic residues
TgeneEIF4E2chr2:233537153chr2:233428956ENST00000258416O60573271_5290.0246.0RegionDisordered
TgeneEIF4E2chr2:233537153chr2:233428956ENST00000258416O605732754_5790.0246.0RegionEIF4EBP1/2/3 binding
TgeneEIF4E2chr2:233537153chr2:233431538ENST00000258416O60573371_52125.0246.0RegionDisordered
TgeneEIF4E2chr2:233537153chr2:233431538ENST00000258416O605733754_57125.0246.0RegionEIF4EBP1/2/3 binding
TgeneEIF4E2chr2:233537153chr2:233431538ENST00000258416O605733795_99125.0246.0RegionEIF4EBP1/2/3 binding


check button - Retained PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Fusion Transcript Sequence for EFHD1_EIF4E2

check button In-frame Fusion Transcript Sequences.
>EFHD1_EIF4E2_ENST00000264059_ENST00000258416_233537153_233428956 length=1723nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAAC
CTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTT
ATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000264059_ENST00000258416_233537153_233431538 length=1618nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCT
GGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000264059_ENST00000409098_233537153_233428956 length=4198nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAG
TACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGC
TAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTC
CTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTT
CTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTG
GGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTC
CAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCT
GGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTAT
GAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGG
ATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCA
GAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGT
GCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTG
TCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTG
TGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGAC
AGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCC
TCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAAT
GTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTA
CTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGA
GAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000264059_ENST00000409098_233537153_233431538 length=4093nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAG
CCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTC
AGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAA
AAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGAT
TTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTG
GAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAA
GTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCT
CTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCT
GACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTT
AAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATG
CTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCT
CGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTAC
CTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAG
AGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCC
TAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTAC
AGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTC
TCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTG
TGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGA
GCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000264059_ENST00000409167_233537153_233428956 length=2263nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAG
TATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAG
GTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGA
TAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGAT
AGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGA
AGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTT
TGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000264059_ENST00000409167_233537153_233431538 length=2158nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTG
CTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTT
AAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGA
CTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACA
GTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTT
CTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000264059_ENST00000409322_233537153_233428956 length=1691nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAAC
CTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTT
ATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000264059_ENST00000409322_233537153_233431538 length=1586nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCT
GGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000264059_ENST00000409394_233537153_233428956 length=1510nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAG
TACACAAGCT

>EFHD1_EIF4E2_ENST00000264059_ENST00000409394_233537153_233431538 length=1405nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000264059_ENST00000409495_233537153_233428956 length=1770nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAG
TATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAG
GTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000264059_ENST00000409495_233537153_233431538 length=1665nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTG
CTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTT
AAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000264059_ENST00000409514_233537153_233428956 length=4275nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATT
ATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACT
GCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGC
TGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAG
TCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACA
TTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAG
TTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTG
AAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGG
CAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAG
GCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAA
GGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAA
TGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCA
AAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCC
TGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGA
GTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGC
AGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGT
TGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGC
ATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGA
TGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAG
AGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTG
AATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGC
TATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000264059_ENST00000409514_233537153_233431538 length=4170nt
Breakpoint=1062nt
CCCAGCCTGTCCCGGGCCGCGAGCGCTTCCAGTCGGGTTACTTCTGGGGGACAAGAAAGGCACCGTCTGAACGGTCGAGACGCTTTTTCCCGCTACGGTTTTCCCCGGAGCTGACAGGGGCAGCAAGGTCGGAGTTGATCCGAGGGTCCC
TGCCTGGTCCCGGGGGGACGGTCAGCCTCCCGCCCGGAGCCGCGGGGAGAGGAAGCAGGTCGGGGTCTCCGGGACGCGCAGACACCCAGACACCGGCGGCCTCCTCCCACCAGGCTGGCAGTCGCTGAGCCCTGGCGCCTCCTTAAAGCC
GCAGCTCCGCCCCGACCGCCCCGCCCGCCAGTCCGTCCTCAGACCCTCCCAACCGCCGGGTCCCCGCCGCCTCGGCGGAGTGTTGTAGAGCCTCGAGCCTGCGAGGAGCGCGCCGCCCGCCAGCTCCCTGCGTCCCGTCCCGCGTCCCCG
CGTTCCCGCGTCCTGCGATCCGCCGCCATGGCCAGTGAGGAGCTGGCGTGCAAGCTGGAGCGCCGGCTGCGGCGCGAGGAGGCCGAGGAGAGTGGCCCCCAGCTGGCTCCCCTCGGCGCCCCAGCCCCGGAGCCCAAGCCCGAGCCCGAG
CCTCCCGCCCGTGCGCCCACGGCCAGCGCCGACGCGGAGCTGAGCGCCCAGCTGAGCCGGCGGCTGGACATCAACGAGGGCGCTGCGCGGCCCCGGCGCTGCAGGGTCTTCAACCCCTACACGGAGTTCCCGGAGTTCAGCCGCCGCCTC
ATCAAGGACCTGGAGAGCATGTTCAAACTGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGAC
TTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTC
TTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTG
TCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATC
AAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTC
TGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTT
TATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACG
AAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGA
CATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCT
GCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGAC
TGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTT
AATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGC
CCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCT
ATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCA
TTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATC
AGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTC
ACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGG
CCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATAC
TGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAG
GTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCC
GCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTT
TCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCG
AAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000409613_ENST00000258416_233537153_233428956 length=1061nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGA
AGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATG
GTGCTAAACTA

>EFHD1_EIF4E2_ENST00000409613_ENST00000258416_233537153_233431538 length=956nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTT
GAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGC
TGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000409613_ENST00000409098_233537153_233428956 length=3536nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCC
TCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAAT
AGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGT
TGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCAC
CACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTT
TCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCT
GTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATC
TGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATG
CTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTC
TTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTT
TTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGA
ATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCC
AAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGT
TGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTG
TTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGAT
ATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGG
AGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTC
TGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGG
AGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000409613_ENST00000409098_233537153_233431538 length=3431nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATA
ATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCAT
CGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCG
TGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAA
TTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTA
GGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGA
GCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTA
TTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGA
TTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGT
CAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAG
TAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCA
AGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGG
GAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGA
GTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCA
AAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTA
GCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAG
TCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTT
ACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCA
CAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000409613_ENST00000409167_233537153_233428956 length=1601nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAG
AAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAA
TTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGT
CTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTG
GCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGA
GGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000409613_ENST00000409167_233537153_233431538 length=1496nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAG
TTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGA
GAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCA
CCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGA
GCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATT
GTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000409613_ENST00000409322_233537153_233428956 length=1029nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGA
AGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000409613_ENST00000409322_233537153_233431538 length=924nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTT
GAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGC
TGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000409613_ENST00000409394_233537153_233428956 length=848nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000409613_ENST00000409394_233537153_233431538 length=743nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000409613_ENST00000409495_233537153_233428956 length=1108nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAG
AAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAA
TTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000409613_ENST00000409495_233537153_233431538 length=1003nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAG
TTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGA
GAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000409613_ENST00000409514_233537153_233428956 length=3613nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCT
GACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGG
GGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACC
TCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAA
AAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCC
TGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCA
GATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATA
GCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTC
CGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTA
GATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAG
GAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCA
TCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAG
TCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCC
TTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACA
GGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTAC
ATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAG
TGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTG
TCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAG
TCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGG
GCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTG
TTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCA
ATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGA
AAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000409613_ENST00000409514_233537153_233431538 length=3508nt
Breakpoint=400nt
GCTAAGTGCAGGCGGATACCCCGGCCTTGGCGGCTGCTTGCCTTTCTCCGTACTGTCCCTGTGAAGGCCAAGATCTGTAACGCTGACAGTCCCCAGACATACGATGGGAGAGTTGCAGTATGACGCTGGGCGGGATGGCTTCATCGACCT
GATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGA
GCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGG
CTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAAC
CACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCC
TCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACT
GAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGT
TCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAAT
GTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATG
TGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGC
CTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGA
GCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATG
GCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCA
GAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTA
AATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTA
CCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCA
GACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCC
CTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTG
AATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTT
CTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGAT
TATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTG
CACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGT
GTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTT
AGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000409708_ENST00000258416_233537153_233428956 length=1288nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGG
CTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAA
TTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000409708_ENST00000258416_233537153_233431538 length=1183nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCT
GTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000409708_ENST00000409098_233537153_233428956 length=3763nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAA
ATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTG
GAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGA
TGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGC
TGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCG
GTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGA
TTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGA
AGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATC
ACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTC
ACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTT
GGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGG
GGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACAT
GGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTG
TGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTC
GTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTC
AGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGC
CAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTT
TGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAAT
AATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAA
ATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000409708_ENST00000409098_233537153_233431538 length=3658nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGA
AGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTC
CATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGT
CTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTG
ATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCT
TAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGC
AGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGC
TTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGA
GAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAA
TTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACC
ACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGA
CAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCT
CCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAA
TCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCT
CCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTA
TGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCA
CAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGT
GTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAG
TGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000409708_ENST00000409167_233537153_233428956 length=1828nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACG
TGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGC
CACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCT
TGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCT
TAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAG
TGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCC
TTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000409708_ENST00000409167_233537153_233431538 length=1723nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGG
GCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATAT
GCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACT
ACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAG
AGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGA
CTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000409708_ENST00000409322_233537153_233428956 length=1256nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGG
CTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAA
TTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000409708_ENST00000409322_233537153_233431538 length=1151nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCT
GTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000409708_ENST00000409394_233537153_233428956 length=1075nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAA
ATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000409708_ENST00000409394_233537153_233431538 length=970nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000409708_ENST00000409495_233537153_233428956 length=1335nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACG
TGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGC
CACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000409708_ENST00000409495_233537153_233431538 length=1230nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGG
GCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATAT
GCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000409708_ENST00000409514_233537153_233428956 length=3840nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATGTGGGAGGATGATGCAAATAAAAAT
GGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCA
ATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTG
AACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGG
GAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTT
TGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAG
AGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAA
GCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCA
CTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCA
GACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGG
GGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCA
GGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACT
TGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTC
CTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACT
CCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAA
AATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTT
TGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTA
TGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCC
TCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGC
CACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCC
AGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGG
AAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000409708_ENST00000409514_233537153_233431538 length=3735nt
Breakpoint=627nt
ACTCTACAGCGTGTATCCGTGGCTGTAACGTGAGCTGGTGGAGCAGTCAAGGTTAGACAGGAAATTTTAATTACCCTGGACTTATCTGGAGGCCTCTTTCAAAGGGAGGCAATGAGGGCAGCCACTTAAAGGCAGGACCCCAATGCAACA
TCTTAAAATGCAGCCGCAAGGTTTTTGCAGCATACTAAAAGCTTGTGTTTTAATTCCCCAAAGAGAGGGTGGGAAGAGGAACATTTGGCTATGGGAAAGTTGTCTTTTTCTTAAGAATCTGAAACGGTGATGTCATGGATGTCCTGCCAG
TGCCAGAGTCCCGCGTTACCAAGACACCAGTGAAACCCAAAAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAG
GAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAA
GGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATC
TGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACT
CACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTG
GCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTC
CAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTC
TTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCC
ATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCC
TTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAA
TTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCA
GGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTG
TGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAA
TAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATA
TGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTAC
AGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGAC
CCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGT
GAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTT
CCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCC
AAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGT
GAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAG
CCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGT
GGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000410095_ENST00000258416_233537153_233428956 length=1013nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAAT
GCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAG
ATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTGCTAAACTA

>EFHD1_EIF4E2_ENST00000410095_ENST00000258416_233537153_233431538 length=908nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGC
TGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACAGCTGAGATCACTTAATAAATGGTG
CTAAACTA

>EFHD1_EIF4E2_ENST00000410095_ENST00000409098_233537153_233428956 length=3488nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGA
CAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTG
CGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCT
TTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTG
TTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGT
ATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCA
GAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTG
TTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCC
TGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTC
CAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAAC
ATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTT
TTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCA
AATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGAC
TGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTG
CTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACA
GGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGG
CAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTC
TAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGT
TCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAAT
TATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000410095_ENST00000409098_233537153_233431538 length=3383nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCC
AGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGA
CAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGA
TGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCAC
TTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCA
CTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTG
TGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGA
GGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTT
TAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTG
TGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTC
CATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATA
TGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAA
GAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGT
TGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTA
GGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATG
CTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGA
GTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGC
TTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGC
AGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAGAA

>EFHD1_EIF4E2_ENST00000410095_ENST00000409167_233537153_233428956 length=1553nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTA
CGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCA
GTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAAT
GAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCA
TTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAG
AATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTC
ATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000410095_ENST00000409167_233537153_233431538 length=1448nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAG
GGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTT
CTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATGTCTTTTTAACTTGTTAGCTTCAGTCTA
TTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGCTGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCA
ATCTCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCTCAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGG
AGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGGTTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTT

>EFHD1_EIF4E2_ENST00000410095_ENST00000409322_233537153_233428956 length=981nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAAT
GCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGCTGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAG
ATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000410095_ENST00000409322_233537153_233431538 length=876nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAAATGCCAGGCAGGCTGGGCCCCCAAAGGCTCCTTTTTCAAAACCTCTGGAAGCCGCGGTTGAATGTGCCATGACCCTCTCCCTCTCTGGATGGCACCATCATTGAAGC
TGGCGTCATCGGAGTCTCTTGTTCTGTTGGCGTGCTACCTGGAAGATCCTTCTGTCCTGGACAAGAGGAATTGGAAGAGCATTTTATGTTTTAAGAACAGGCTGACACGCAGCAGCTACAACAACA

>EFHD1_EIF4E2_ENST00000410095_ENST00000409394_233537153_233428956 length=800nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGA
CAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000410095_ENST00000409394_233537153_233431538 length=695nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCT

>EFHD1_EIF4E2_ENST00000410095_ENST00000409495_233537153_233428956 length=1060nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTA
CGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCA
GTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAAT
GAAAGACAAG

>EFHD1_EIF4E2_ENST00000410095_ENST00000409495_233537153_233431538 length=955nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGTACGTGTTGGGGGGTTATGGGAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAG
GGACAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTGTAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTT
CTACAGGCTGTCTTGTCTTTCATATGCTAACCACTATCTTAAAATGAAAGACAAG

>EFHD1_EIF4E2_ENST00000410095_ENST00000409514_233537153_233428956 length=3565nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTGGAGCAGTTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCAT
GTGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGT
CCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCCCAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGC
CTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAATCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTAT
GTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGGAGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAA
AGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGATGCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGG
TACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCTGTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTT
TGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGGTCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACT
TAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGATTATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGA
CTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAAGGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATAT
GCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCACCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGG
CAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCACAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGC
AACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTGGCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCC
TTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGGGCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATA
AGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATGGAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTT
TGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGTGTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCC
TGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCGTTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCC
CTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCAGTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTT
TTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCCAACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTT
GCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGT
TTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATAATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAA
TGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAATATCAGCAAG

>EFHD1_EIF4E2_ENST00000410095_ENST00000409514_233537153_233431538 length=3460nt
Breakpoint=352nt
AGGAATTACATGTTTCGGAGACTAACGAGTGTCCTTTCATCCCGGTCATGCATTCCTTTGACCCTGCAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCA
CCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGAT
CGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTGGCCATGCTGGGGGA
ACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGAAGACATTATTTCAATATGGAATAAGACTGCCAGTGACCAAGCAACCACAGCCCGAATCCGGGACACACTTCGGCGAGTGCTTAACCTACCTCC
CAACACCATTATGGAATACAAAACTCACACCGACAGCATCAAGGCCTGGGAGGAGTTTCATGGCCTGGTGAACAGCAGCGGCCGCTGATCGGACGCTCCCCCTCTGTCTCTCACACTCAGGGGACAATTCAAGCTTTCGAAATACAAAAA
TCACATTGTGAGAGTACACAAGCTGGCAATAATCCTTTTCTGTATGTGTGTGTTTGTCCGAAATGGATGGGAGGCCTCCAGCCAGTCCTTCCATTGCTCACTGAAGGGACGTCCCTGAGCCGTGCGCTCTCCTTTTGCACTCATTCCTGG
AGGACGGATTCCGCTAGACACCCTCCAGCATCGCTGACTTTATAAAGCGGAAAAACGGAAAACGTGACTTTGTAATAGACAAACATTGTTTTTTAATGGGGTTCCATGGGGGGGCGTTCAGCCTTTCTGTTTGCTGTGTGCTGTCCAGAT
GCCTCTTGGGCGTCCTGTTGTTCTCTTCCCGTGTTGTACGAAGGGTACCGTGGCCACGTGTACATGCCAGAGCTGTTGATGAGAGTTACCAGTATTATGAATGTCTGTGCATCCAGGAAAAGTGTTCTGTTGGAGAGTCCCAAAATAGCT
GTAAATGCTCTCTTCTAGCTCTGCCATTAAATTATTGGGACATTTTGTTTCTTTCTCTCCCCTCCTCCAAGCCCACCACTTTCTGAAGCTGTGTTACTGATGTGATGACTGTCCAGGATTTTGTATCATCCCCTGCCTTATGCCCTCCGG
TCTCCTCTCCTGTGGGACTCTCTCCTTCTTAGGCACAGCTGCACTTAGAATTGTAATCCAGTGGCTCTCACTGGTTTCACTGAGGCAGCTTAGAGGGAATGCCTTAGTAAACTGAACTGGAGCAGAATCTAGTTTGATTAGGAGCTAGAT
TATAATCTAGGTTCCAAGTACAGAATTTGGAGCTAAGGACTGTGACTGAAATCATTTTCCCATATGAGCAGACCCTGTGTGTCAGGCCTGTTTCCCATATGAGCAGAGCCTGTGTGCAAGTCTGTTTCTGGCATGTCCCTCATTGAGGAA
GGGAAGCAAAAGCTGGTTATTGCCAGGCCTATTAACACTTAATATGCAAATTCTATCATCCTGAAACTGGGGCATCTGAGGAAAAGGTGACCTTGCTGGATGGCTTTATTTGCATGGCTCTGCCTGTCTGCAGTGGTTGAGTCCTCATCA
CCTGGTATGTGTATGAGCAAATGTGTGCTGATTGTGATGCCCAGGCAGAAACCTCTTGAAGACTGCTGCAGGCATGCTTTAAAAATGACCAGTCACTCATCAGAGAAGCTGGGTGATCTGACTCCAGAAGGACTGAAGTCAGAGAAGTCA
CAAGAGCACCTAGGATTCAAATAAATAGCGTCAGAGTCCTATAGCAACCTCCAAGTAGCACCGTCTTACTTGGCTCTTGTGAGCAAAGACTGCAGTACCTTAAATTAAGGCCTCTCTTTAAAACATATGTGGAAGACTAGGGGATCCTTG
GCCACCTGGTCTCAGAGAAATCATATGAGAGTAACAGGCATTTCCTTATTGTATTTGTACTACACTCTTCCTACTTTTCCATTCCTGAACACCCTCTAATTACCACTGTTTTGGGGATGCTTTTTTTCTGAAAGAACGGGGAGTACAGGG
GCCAAAAGGGAGGTGCTTCTATTACAGGGCAAGTTAGATCAGATAAGAAGATCTAGCAGTGATTTAAACTCCAGGAATATGAAGAGTGCATTCTGGTGTCCAGACAGTTGTGAAGGGCTCGGCAAATATAAGAGCACCATTGGCTACATG
GAGAGCAAAGGCTGTCTTTGAAGACCCCAGGGAGGTCTTCACTTTTGCCTAAATTCAGATTTGCCGTGAAAATTCCAAAGAGAGCAGATATTTGGATTTGCCCTCCTTTGGGCATCTACCTGACTGTTGTGTGTGTGGGAAAGTCAGTGT
GTATGTGTAGAGTGTGCTTAGGAGTGAGTGAGTGGTCAGGCCTCCTGGCTAGGTGTGTTGTCCATAGTTTTGTTGTTGTTGTTGTTGTTGTTCAGAGTTTTGAATCTTACGTTTTCTAGAGCTGCTCATGTTTTCCCTTCCTTTTTGTCG
TTGTAGTATTTGACAGTTGTCTTTTCCATCAAAAACATACTGGCCCTAGGCTGGTTAGAGCAAGGGGTTATGCCTGTTAGGCAGCATCTTACGCCCAGTGTTCTCCCAGATATTCTGCCTAACAGGTTTAAGTAGGAGATTAAATAGTCA
GTTTATCTAAACCCTCTATTTTTCCAAACTAGCTTGAGAGGTCTTTTCATCTATTTTTACTCCATGGGCCTCTGATATGCTGAGATGTGGCACGGTTATGATTATGGTATCACCGTTACAGAGGCAAAGGGATAAAGGTCTACCAGGGCC
AACGTAACCAGAATGTGAGGAGAGTGAAGAGTCGGTCTCCGCTTTGCACAGTACCAGAATGTGAGGTTGCCACTGGAGAGTGGAGAGTCGGTCTCCACTTTGCACAGTTGGAGCTGTTCTCCTCTAACTCCTTTGCTGGGTTTTCTGTTT
GAAATTGGCCCCTACTCCTCTCCAGCCCTTTACTGGGTTTTCTGTTTGAAATTGGCCCCTACTCCTCTCCAGTGTCTGCTTTTTGAATCCTTCTGTTCGTGTGTGTGTGTGTGTGTGTGTGTGTTCCCTATGATACTGGCAGTGGCAATA
ATTTTCCACCCAGAGAGAAGCTTGTGGTCCACAATGCTCGAAGAATGAATTTCCAAGTATTTGCCAGTGGAAACGGAGCAGAGGCTATGACAAGAGTGATTTAGTGTTGCACTTTCAGAGCAATTATCTACTGCAGTAATAAATTGAAAA
TATCAGCAAG


check button N-Truncated Transcript (5UTR-3CDS) Sequences

check button C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for EFHD1_EIF4E2

check button In-frame Fusion Protein Sequences.

check button N-Truncated Protein (5UTR-3CDS) Sequences

check button C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for EFHD1_EIF4E2


check button TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences
NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button TCGA All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

check button CCLE All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

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Fusion Gene Exprssed Samples for EFHD1_EIF4E2


check buttonRNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDBBRCATCGA-AO-A0JE-01AEFHD1

chr2

233537153-EIF4E2

chr2

0

+
ChimerDBBRCATCGA-AO-A0JE-01AEFHD1

chr2

233537153+EIF4E2

chr2

233428957

+
ChimerDBBRCATCGA-AO-A0JE-01AEFHD1

chr2

233537153+EIF4E2

chr2

233537153

+
ChimerDBBRCATCGA-C8-A12Q-01AEFHD1

chr2

233537153-EIF4E2

chr2

0

+
ChimerDBBRCATCGA-C8-A12Q-01AEFHD1

chr2

233537153+EIF4E2

chr2

233431539

+
ChimerDBBRCATCGA-C8-A12Q-01AEFHD1

chr2

233537153+EIF4E2

chr2

233537153

+
TCGAfusionPortalBRCATCGA-AO-A0JE-01AEFHD1

chr2

233537153+EIF4E2

chr2

233428957

+
TCGAfusionPortalBRCATCGA-C8-A12Q-01AEFHD1

chr2

233537153+EIF4E2

chr2

233431539

+
WashUBRCATCGA-AO-A0JE-01AEFHD1

chr2

233537153+EIF4E2

chr2

233428957

+
WashUBRCATCGA-C8-A12Q-01AEFHD1

chr2

233537153+EIF4E2

chr2

233431539

+
cBioPortalBRCA_TCGA_PAN_CAN_ATLAS_2018BRCATCGA-AO-A0JE-01EFHD1

chr2

232672443EIF4E2

chr2

232564247

cBioPortalBRCA_TCGA_PAN_CAN_ATLAS_2018BRCATCGA-C8-A12Q-01EFHD1

chr2

232672443EIF4E2

chr2

232566829


check buttonDNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrandSV type


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Related Drugs for EFHD1_EIF4E2


check button PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.
PMIDFusion Gene NameDrugStudy Title

check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status