|
||||||
|
Fusion gene:DIAPH3_DOK5 (FusionGDB2 ID:HG81624TG55816) |
Fusion Gene Summary for DIAPH3_DOK5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DIAPH3_DOK5 | Fusion gene ID: hg81624tg55816 | Hgene | Tgene | Gene symbol | DIAPH3 | DOK5 | Gene ID | 81624 | 55816 |
| Gene name | diaphanous related formin 3 | docking protein 5 | |
| Synonyms | AN|AUNA1|DIA2|DRF3|NSDAN|diap3|mDia2 | C20orf180|IRS-6|IRS6 | |
| Cytomap | 13q21.2 | 20q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein diaphanous homolog 3diaphanous homolog 3 | docking protein 5downstream of tyrosine kinase 5insulin receptor substrate 6 | |
| Modification date | 20240403 | 20240411 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000267215, ENST00000377908, ENST00000400319, ENST00000400320, ENST00000400324, ENST00000400330, ENST00000465066, | ||
| Fusion gene scores | * DoF score | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 7 X 14 X 7=686 | * DoF score (Degree of Frequency) = # partners X # break points X # disease types 6 X 24 X 12=1728 |
| # samples | 20 | 24 | |
| ** MAII score | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(20/686*10)=-1.77820857639809 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) log2(24/1728*10)=-2.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DIAPH3 [Title/Abstract] AND DOK5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DIAPH3(60582677)-DOK5(53266953), # samples:1 | ||
| Fusion gene breakpoints across DIAPH3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across DOK5 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Fusion Gene Breakpoints for DIAPH3_DOK5 |
| RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp |
| DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 |
| DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 60582677 |
| DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section. |
| Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | SV type |
Top |
Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for DIAPH3_DOK5 |
| To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence. |
| Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions | Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity | Epigenetic Reprogramming / Histone Modifier Dysregulation | Chromatin Remodeling Dysregulation | Condensate-Driven Transcriptional Rewiring / LLP | Promoter / Enhancer Hijacking | Dominant-Negative Antagonism | Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation | Subcellular Mislocalization / Spatial Dysregulation | Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade |  |  |  |  |  |  |  |  |  |  |
* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
| Fusion Gene Name | Mechanism Category | Mechanism PubMed | Tumorigenic Scenarios | Tumorigenic Scenario PubMed | Targeting Points | Targeting PubMed | Mechanism Background | Mechanism Background PubMed |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
Top |
Fusion Genomic Features for DIAPH3_DOK5 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + | 4.48e-07 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + | 4.48e-07 | 1.00e+00 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases). |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF). |
 |
Top |
Fusion Gene ORF Annotations for DIAPH3_DOK5 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000465066 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| 5UTR-3CDS | ENST00000465066 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000267215 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000377908 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000400319 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000400320 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000400324 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| Frame-shift | ENST00000400330 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000267215 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000377908 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000400319 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000400320 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000400324 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| In-frame | ENST00000400330 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + |
| ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000267215 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1014 | 332 |
| ENST00000377908 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 981 | 297 |
| ENST00000400319 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 804 | 380 |
| ENST00000400320 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 876 | 273 |
| ENST00000400324 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1235 | 200 |
| ENST00000400330 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1233 | 380 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| ENST00000465066 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 0 | 85 |
| ENST00000465066 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 0 | 59 |
| ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | Seq length (transcript) | Seq length (peptide) |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000267215 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 2.19e-03 | 9.98e-01 |
| ENST00000377908 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1.52e-03 | 9.98e-01 |
| ENST00000400319 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 2.29e-03 | 9.98e-01 |
| ENST00000400320 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 3.70e-03 | 9.96e-01 |
| ENST00000400324 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1.73e-03 | 9.98e-01 |
| ENST00000400330 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 1.79e-03 | 9.98e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
| ENST00000465066 | ENST00000262593 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 0.00e+00 | 6.33e-01 |
| ENST00000465066 | ENST00000395939 | DIAPH3 | chr13 | 60582677 | DOK5 | chr20 | 53266953 | 0.00e+00 | 7.83e-01 |
| DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins). |
| Henst | Tenst | Hgene | Hchr | Hbp | Tgene | Tchr | Tbp | No-coding score | Coding score |
Top |
Fusion Protein Retained/Non-Retained Functional Features for DIAPH3_DOK5 |
| Protein Level Annotation from FGviewer * Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS. |
 |
| - In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length). |
DIAPH3_DOK5_chr13-60582677_chr20-53266953.png |
| - In-frame and retained protein feature among the 13 regional features (texts). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 1_10 | 338.0 | 1113.0 | Compositional bias | Basic residues |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 36_60 | 338.0 | 1113.0 | Motif | Nuclear localization signal |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 1_57 | 338.0 | 1113.0 | Region | Disordered |
| Tgene | DOK5 | chr13:60582677 | chr20:53266953 | ENST00000395939 | Q9P104 | 6 | 8 | 263_273 | 177.33333333333334 | 199.0 | Motif | Note=DKFBH motif |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 1013_1056 | 338.0 | 1113.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 497_554 | 338.0 | 1113.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 575_600 | 338.0 | 1113.0 | Compositional bias | Pro residues |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 1057_1087 | 338.0 | 1113.0 | Domain | DAD |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 114_476 | 338.0 | 1113.0 | Domain | GBD/FH3 |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 561_631 | 338.0 | 1113.0 | Domain | Note=FH1 |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 636_1034 | 338.0 | 1113.0 | Domain | FH2 |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 1184_1193 | 338.0 | 1113.0 | Motif | Nuclear export signal |
| Hgene | DIAPH3 | chr13:60582677 | chr20:53266953 | ENST00000267215 | Q9NSV4 | 9 | 27 | 558_622 | 338.0 | 1113.0 | Region | Disordered |
| Tgene | DOK5 | chr13:60582677 | chr20:53266953 | ENST00000395939 | Q9P104 | 6 | 8 | 132_237 | 177.33333333333334 | 199.0 | Domain | IRS-type PTB |
| Tgene | DOK5 | chr13:60582677 | chr20:53266953 | ENST00000395939 | Q9P104 | 6 | 8 | 8_112 | 177.33333333333334 | 199.0 | Domain | Note=PH |
| - Retained PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Hgene | Hbp | Tgene | Tbp | ENST | UniProt | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Fusion Transcript Sequence for DIAPH3_DOK5 |
| In-frame Fusion Transcript Sequences. |
>DIAPH3_DOK5_ENST00000267215_ENST00000395939_60582677_53266953 length=1490nt Breakpoint=1014nt ATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTCTCCGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCC GAGGAGCCTGGGGAGAAGCGCCCCAAGTTTCATTTAAATATTAGGACACTGACGGATGATATGCTGGACAAATTTGCCAGCATAAGAATTCCAGGGAGCAAGAAAGAGAGACCTCCACTTCCCAACCTGAAGACTGCATTTGCAAGCAGT GATTGCTCAGCAGCACCTTTAGAGATGATGGAGAACTTTCCAAAGCCACTGTCAGAGAATGAACTCTTAGAACTTTTTGAAAAAATGATGGAAGATATGAATTTAAATGAAGATAAAAAGGCACCATTGCGGGAAAAGGACTTCAGTATC AAAAAAGAAATGGTGATGCAGTACATTAATACTGCTTCTAAGACAGGAAGTCTTAAGAGAAGCCGACAGATCTCACCTCAGGAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTGGAGTCTCTCCGA GTGTCTTTGACCAGCAATCCTGTGAGTTGGGTGGAAAGCTTTGGACATGAAGGGCTTGGATTATTATTAGACATTTTGGAAAAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTCATACAGTGTCTA AAAGCCCTGATGAATACGCAGTATGGCTTGGAAAGAATTATGAGTGAGGAGAGGAGCCTTTCCTTATTGGCCAAAGCCGTGGATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGCATTGTAGGGGAA GAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTAACTTCAGCTGGTGAAGAAAAAAAAATTGACAGATTTTTTTGTATTGTGGAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGA CTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAA TTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGA AATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGTTA >DIAPH3_DOK5_ENST00000377908_ENST00000395939_60582677_53266953 length=1457nt Breakpoint=981nt ATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTCTCCGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCC GAGGAGCCTGGGGAGAAGCGCCCCAAGTTTCTGGACAAATTTGCCAGCATAAGAATTCCAGGGAGCAAGAAAGAGAGACCTCCACTTCCCAACCTGAAGACTGCATTTGCAAGCAGTGATTGCTCAGCAGCACCTTTAGAGATGATGGAG AACTTTCCAAAGCCACTGTCAGAGAATGAACTCTTAGAACTTTTTGAAAAAATGATGGAAGATATGAATTTAAATGAAGATAAAAAGGCACCATTGCGGGAAAAGGACTTCAGTATCAAAAAAGAAATGGTGATGCAGTACATTAATACT GCTTCTAAGACAGGAAGTCTTAAGAGAAGCCGACAGATCTCACCTCAGGAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTGGAGTCTCTCCGAGTGTCTTTGACCAGCAATCCTGTGAGTTGGGTG GAAAGCTTTGGACATGAAGGGCTTGGATTATTATTAGACATTTTGGAAAAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTCATACAGTGTCTAAAAGCCCTGATGAATACGCAGTATGGCTTGGAA AGAATTATGAGTGAGGAGAGGAGCCTTTCCTTATTGGCCAAAGCCGTGGATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGCATTGTAGGGGAAGAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTA ACTTCAGCTGGTGAAGAAAAAAAAATTGACAGATTTTTTTGTATTGTGGAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGT AACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAAT AATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTG CACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGTTA >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953 length=1280nt Breakpoint=804nt ATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTCTCCGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCC GAGGAGCCTGGGGAGAAGCGCCCCAAGTTTGAAGATATGAATTTAAATGAAGATAAAAAGGCACCATTGCGGGAAAAGGACTTCAGTATCAAAAAAGAAATGGTGATGCAGTACATTAATACTGCTTCTAAGACAGGAAGTCTTAAGAGA AGCCGACAGATCTCACCTCAGGAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTGGAGTCTCTCCGAGTGTCTTTGACCAGCAATCCTGTGAGTTGGGTGGAAAGCTTTGGACATGAAGGGCTTGGA TTATTATTAGACATTTTGGAAAAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTCATACAGTGTCTAAAAGCCCTGATGAATACGCAGTATGGCTTGGAAAGAATTATGAGTGAGGAGAGGAGCCTT TCCTTATTGGCCAAAGCCGTGGATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGCATTGTAGGGGAAGAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTAACTTCAGCTGGTGAAGAAAAAAAAATT GACAGATTTTTTTGTATTGTGGAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTG TGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTT TAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGG ATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGTTA >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953 length=1352nt Breakpoint=876nt ATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTCTCCGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCC GAGGAGCCTGGGGAGAAGCGCCCCAAGTTTCTGGACAAATTTGCCAGCATAAGAATTCCAGGGAGCAAGAAAGAGAGACCTCCACTTCCCAACCTGAAGACTGCATTTGCAAGCAGTGATTGCTCAGCAGCACCTTTAGAGATGATGGAG AACTTTCCAAAGCCACTGTCAGAGAATGAACTCTTAGAACTTTTTGAAAAAATGATGGGAAGTCTTAAGAGAAGCCGACAGATCTCACCTCAGGAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTG GAGTCTCTCCGAGTGTCTTTGACCAGCAATCCTGTGAGTTGGGTGGAAAGCTTTGGACATGAAGGGCTTGGATTATTATTAGACATTTTGGAAAAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTC ATACAGTGTCTAAAAGCCCTGATGAATACGCAGTATGGCTTGGAAAGAATTATGAGTGAGGAGAGGAGCCTTTCCTTATTGGCCAAAGCCGTGGATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGC ATTGTAGGGGAAGAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTAACTTCAGCTGGTGAAGAAAAAAAAATTGACAGATTTTTTTGTATTGTGGAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTC ATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAA AGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAG TCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGT TA >DIAPH3_DOK5_ENST00000400324_ENST00000395939_60582677_53266953 length=1711nt Breakpoint=1235nt ATTGATCCGGCGGCGCGGGATTGGCCAGTCCCGGGCCAACACGGGTGGCGGGAGTTTTCAGATGTGTTGGCTGCGGCCCCGACTTCAGCGGTTGGGCTAGGCTGTGCTGACTGTTTGGGTGGCGGACCCCGGGAGTAAAACCTGTTGTCG ATCCCTCAGCTTCCAGCTTGCGGCTTGCTGAGTGGCCACCTTCTTTCCGGTCCCCGGAGCTGCGGGGAAAGATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTC TCCGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCCGAGGAGCCTGGGGAGAAGCGCCCCAAGTTTCATTTAAATATTAGGACACTGACGGATGATATGCTGGACAAATTTGCCA GCATAAGAATTCCAGGGAGCAAGAAAGAGAGACCTCCACTTCCCAACCTGAAGACTGCATTTGCAAGCAGTGATTGCTCAGCAGCACCTTTAGAGATGATGGAGAACTTTCCAAAGCCACTGTCAGAGAATGAACTCTTAGAACTTTTTG AAAAAATGATGGAAGATATGAATTTAAATGAAGATAAAAAGGCACCATTGCGGGAAAAGGACTTCAGTATCAAAAAAGAAATGGTGATGCAGTACATTAATACTGCTTCTAAGACAGGAAGTCTTAAGAGAAGCCGACAGATCTCACCTC AGGAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTGGAGTCTCTCCGAGTGTCTTTGACCAGCAATCCTGTGAGTTGGGTGGAAAGCTTTGGACATGAAGGGCTTGGATTATTATTAGACATTTTGG AAAAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTCATACAGTGTCTAAAAGCCCTGATGAATACGCAGTATGGCTTGGAAAGAATTATGAGTGAGGAGAGGAGCCTTTCCTTATTGGCCAAAGCCG TGGATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGCATTGTAGGGGAAGAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTAACTTCAGCTGGTGAAGAAAAAAAAATTGACAGATTTTTTTGTATTG TGGAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGAT TCACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTG AAACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTC CAAGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGTTA >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953 length=1709nt Breakpoint=1233nt TGATCCGGCGGCGCGGGATTGGCCAGTCCCGGGCCAACACGGGTGGCGGGAGTTTTCAGATGTGTTGGCTGCGGCCCCGACTTCAGCGGTTGGGCTAGGCTGTGCTGACTGTTTGGGTGGCGGACCCCGGGAGTAAAACCTGTTGTCGAT CCCTCAGCTTCCAGCTTGCGGCTTGCTGAGTGGCCACCTTCTTTCCGGTCCCCGGAGCTGCGGGGAAAGATGGAACGGCACCAGCCGCGGCTGCACCACCCGGCCCAAGGCTCAGCCGCTGGGACTCCCTACCCTTCCTCAGCCTCTCTC CGCGGCTGCCGGGAAAGCAAGATGCCGCGCAGGAAGGGCCCCCAACACCCTCCGCCGCCCAGTGGCCCCGAGGAGCCTGGGGAGAAGCGCCCCAAGTTTCATTTAAATATTAGGACACTGACGGATGATATGCTGGACAAATTTGCCAGC ATAAGAATTCCAGGGAGCAAGAAAGAGAGACCTCCACTTCCCAACCTGAAGACTGCATTTGCAAGCAGTGATTGCTCAGCAGCACCTTTAGAGATGATGGAGAACTTTCCAAAGCCACTGTCAGAGAATGAACTCTTAGAACTTTTTGAA AAAATGATGGAAGATATGAATTTAAATGAAGATAAAAAGGCACCATTGCGGGAAAAGGACTTCAGTATCAAAAAAGAAATGGTGATGCAGTACATTAATACTGCTTCTAAGACAGGAAGTCTTAAGAGAAGCCGACAGATCTCACCTCAG GAATTCATTCATGAGCTGAAAATGGGGTCTGCAGATGAGAGACTTGTCACATGCCTGGAGTCTCTCCGAGTGTCTTTGACCAGCAATCCTGTGAGTTGGGTGGAAAGCTTTGGACATGAAGGGCTTGGATTATTATTAGACATTTTGGAA AAACTGATTAGTGGAAAAATCCAAGAAAAAGTTGTAAAGAAAAATCAACATAAAGTCATACAGTGTCTAAAAGCCCTGATGAATACGCAGTATGGCTTGGAAAGAATTATGAGTGAGGAGAGGAGCCTTTCCTTATTGGCCAAAGCCGTG GATCCCAGACACCCCAATATGATGACAGATGTGGTTAAACTTCTCTCTGCGGTATGCATTGTAGGGGAAGAAAGCATCCTTGAAGAAGTTTTAGAAGCTTTAACTTCAGCTGGTGAAGAAAAAAAAATTGACAGATTTTTTTGTATTGTG GAAGGCCTCCGGCACAATTCAGTTCAACTGCAAATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTC ACCCAGGAGGTCACAGAATGACAGCAAGGGAAATGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAA ACGTGCTCTATAGATATTGACTCTGTGTTCCCTCTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCA AGTGTTTCAGTTGTATGACAGTCAGTATTGACAATAAAATGGCTTTTAATTATTTGTTA |
| N-Truncated Transcript (5UTR-3CDS) Sequences |
>DIAPH3_DOK5_ENST00000465066_ENST00000262593_60582677_53266953 length=757nt Breakpoint=0nt ATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAA TGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCT CTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACA ATAAAATGGCTTTTAATTATTTGTTATTTGTTTACACCCTATTCCTCAGTTATTATTACTGTGGTTCTGATTAACTACTGGAAATTATATTTGATTATATCACCAATTAGTTAAATCAGTGCTTCGACTCACTCTTATCTGTTCTGTTCA AAACTATTTGTTCAAAGAACCCGTTAGTGTTGTTTACAGGGTTACAGTTTCTCTCACATGCTTTCCTCACCCCTTTACCCCCCTTTTTGAAAGCCTTTATTTTGTTCGGAGTCTCTTCATAAAACATTTGAAAATAAAAGATCATTCTTC ACCCATA >DIAPH3_DOK5_ENST00000465066_ENST00000395939_60582677_53266953 length=476nt Breakpoint=0nt ATGTTTCCAGCCCTCTGAAGCTTCATCGAACAGAGACTTTTCCAGCCTACAGATCTGAGCACTGACAGTAACTGCCAAGAATTGTTAACACACTTGTGATGTGTCAGCCACAGATTCACCCAGGAGGTCACAGAATGACAGCAAGGGAAA TGACGACCAAGAGAAGAAGCTTAAAGTCCTGGCTAATTGTGTGGTCATTGGAAAACTCTGCAATACAATAATTTTCTTTATTTTCTTTTTCTTTTTTAAATTCTTAGTGTAATTGAAACGTGCTCTATAGATATTGACTCTGTGTTCCCT CTTTTACAGCTGGACAGAAAGAAGTCAATGTCACGAAATGATTTTCTATTGTAGATACTTTGTCCCTTGCACTTCTCTGAATCTGTCCTTTTGTGGATTCTTGTGATTTTCCTTCCAAGTGTTTCAGTTGTATGACAGTCAGTATTGACA ATAAAATGGCTTTTAATTATTTGTTA |
| C-Truncated Transcript (5CDS-3UTR) Sequences |
Top |
Fusion Protein Sequence for DIAPH3_DOK5 |
| In-frame Fusion Protein Sequences. |
>DIAPH3_DOK5_ENST00000267215_ENST00000395939_60582677_53266953 length=332nt MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENFPKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINT ASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEAL TSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000377908_ENST00000395939_60582677_53266953 length=297nt MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENFPKPLSENELLELFEKMMGSLKRSRQISPQEFIHELKMGSADERLVTCL ESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953 length=380nt MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953 length=273nt MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400324_ENST00000395939_60582677_53266953 length=200nt MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLNEEKKAPLRNKDFTTKREMVVQYISATAKSV FQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953 length=380nt MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL |
| N-Truncated Protein (5UTR-3CDS) Sequences |
>DIAPH3_DOK5_ENST00000465066_ENST00000262593_60582677_53266953 length=85nt MSSPKTAAGTPQIKGCSSKTPLLKLDSLGQRKVFTVVDSTSRPSHVLFPGITARLPATTSVLFSSKGTSNLSPTCWNVDIYNATV >DIAPH3_DOK5_ENST00000465066_ENST00000395939_60582677_53266953 length=59nt MIFYFQMFYEETPNKIKAFKKGGKGVRKACERNCNPVNNTNGFFEQIVLNRTDKSESKH |
| C-Truncated Protein (5CDS-3UTR) Sequences |
Top |
Personalized Fusion Protein Sequence for DIAPH3_DOK5 |
| TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences |
| Num | Gene Group | Domain Loci | Fusion Protein ID | Fusion Gene Name | Partner | Mutated Residue in WT Protein | Seq. Length | Mutated Residue in Fusion Protein |
| TCGA All Mutated Fusion Protein Sequences |
>DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.N112K_380_N149K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMEKF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R200Q_380_R237Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLQVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.Q257L_380_Q294L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTLYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.E236K_380_E273K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQKKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.G14S_380_G51S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQSSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K228Q_380_K265Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEQLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.W210C_380_W247C length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.N92T_380_N129T length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPTLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.W210C_380_W247C length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K94N_380_K131N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLNTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.D189Y_380_D226Y length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSAYERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.V246F_380_V283F length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKFIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K115E_380_K152E length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PEPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.S213I_380_S250I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVEIFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.S269N_380_S306N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERNLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.E212D_380_E249D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVDSFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.E124D_380_E161D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLDLFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K94N_380_K131N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLNTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R172Q_380_R209Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R331Q_380_R368Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R331Q_380_R368Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.V298I_380_V335I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIIGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.P88H_380_P125H length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERHPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.A105T;p.E127G_380_A142T;E164G length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSATPLEMMENF PKPLSENELLELFGKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.N283K_380_N320K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPKMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.L196M_380_L233M length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCMESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.S293F_380_S330F length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLFAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.S103L_380_S140L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCLAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.G166R_380_G203R length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTRSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.A294V_380_A331V length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSVVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K233Q_380_K270Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGQIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.G40S_380_G77S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKSPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.F179S_380_F216S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQESIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.D287N_380_D324N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTNVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.V295L_380_V332L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSALCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.A12V_380_A49V length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPVQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R65M_380_R102M length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIMTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.R172Q_380_R209Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.E55D_380_E92D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGDKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K74R_380_K111R length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDRFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.K318Q_380_K355Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEQKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.P88S_380_P125S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERSPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.P50S_380_P87S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGSEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.A104S_380_A141S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSSAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.A314P_380_A351P length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSPGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400319_ENST00000395939_60582677_53266953_5-gene_p.S175L_380_S212L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQILPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R262I_273_R192I length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEIIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R200Q_273_R130Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLQVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.Q257L_273_Q187L length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTLYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.E236K_273_E166K length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQKKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.G14S_273_G14S length=273AA MERHQPRLHHPAQSSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.K228Q_273_K158Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEQLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.W210C_273_W140C length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.W210C_273_W140C length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.D189Y_273_D119Y length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSAYERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.V246F_273_V176F length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKFIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.S213I_273_S143I length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVEIFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.S269N_273_S199N length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERNLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.E212D_273_E142D length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVDSFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R262I_273_R192I length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEIIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R262I_273_R192I length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEIIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R172Q_273_R102Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R331Q_273_R261Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R331Q_273_R261Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.V298I_273_V228I length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIIGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.N283K_273_N213K length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPKMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.L196M_273_L126M length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCMESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.S293F_273_S223F length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLFAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.G166R_273_G96R length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTRSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.A294V_273_A224V length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSVVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.K233Q_273_K163Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGQIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.G40S_273_G40S length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKSPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.F179S_273_F109S length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQESIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.D287N_273_D217N length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTNVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.V295L_273_V225L length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSALCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.A12V_273_A12V length=273AA MERHQPRLHHPVQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.R172Q_273_R102Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.E55D_273_E55D length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGDKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.K318Q_273_K248Q length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEQKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.P50S_273_P50S length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGSEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.A314P_273_A244P length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSPGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400320_ENST00000395939_60582677_53266953_5-gene_p.S175L_273_S105L length=273AA MERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQILPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLG LLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERIMSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.N112K_380_N149K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMEKF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R200Q_380_R237Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLQVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.Q257L_380_Q294L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTLYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.E236K_380_E273K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQKKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.G14S_380_G51S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQSSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K228Q_380_K265Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEQLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.W210C_380_W247C length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.N92T_380_N129T length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPTLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.W210C_380_W247C length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSCVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K94N_380_K131N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLNTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.D189Y_380_D226Y length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSAYERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.V246F_380_V283F length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKFIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K115E_380_K152E length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PEPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.S213I_380_S250I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVEIFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.S269N_380_S306N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERNLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.E212D_380_E249D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVDSFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R262I_380_R299I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLEII MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.E124D_380_E161D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLDLFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K94N_380_K131N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLNTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R172Q_380_R209Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R331Q_380_R368Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R331Q_380_R368Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLQHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.V298I_380_V335I length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIIGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.P88H_380_P125H length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERHPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.A105T;p.E127G_380_A142T;E164G length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSATPLEMMENF PKPLSENELLELFGKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.N283K_380_N320K length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPKMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.L196M_380_L233M length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCMESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.S293F_380_S330F length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLFAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.S103L_380_S140L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCLAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.G166R_380_G203R length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTRSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.A294V_380_A331V length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSVVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K233Q_380_K270Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGQIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.G40S_380_G77S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKSPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.F179S_380_F216S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQESIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.D287N_380_D324N length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTNVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.V295L_380_V332L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSALCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.A12V_380_A49V length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPVQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R65M_380_R102M length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIMTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.R172Q_380_R209Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSQQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.E55D_380_E92D length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGDKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K74R_380_K111R length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDRFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.K318Q_380_K355Q length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEQKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.P88S_380_P125S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERSPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.P50S_380_P87S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGSEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.A104S_380_A141S length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSSAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.A314P_380_A351P length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQISPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSPGEEKKIDRFFCIVEGLRHNSVQLQMFPAL >DIAPH3_DOK5_ENST00000400330_ENST00000395939_60582677_53266953_5-gene_p.S175L_380_S212L length=380AA MFGWRTPGVKPVVDPSASSLRLAEWPPSFRSPELRGKMERHQPRLHHPAQGSAAGTPYPSSASLRGCRESKMPRRKGPQHPPPPSGPEEPGEKRPKFHLNIRTLTDDMLDKFASIRIPGSKKERPPLPNLKTAFASSDCSAAPLEMMENF PKPLSENELLELFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLKRSRQILPQEFIHELKMGSADERLVTCLESLRVSLTSNPVSWVESFGHEGLGLLLDILEKLISGKIQEKVVKKNQHKVIQCLKALMNTQYGLERI MSEERSLSLLAKAVDPRHPNMMTDVVKLLSAVCIVGEESILEEVLEALTSAGEEKKIDRFFCIVEGLRHNSVQLQMFPAL |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-06-5412-01A | 5-gene | p.N112K | 380 | N149K |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-06-5416-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-17-Z055-01A | 5-gene | p.R200Q | 380 | R237Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-18-3414-01A | 5-gene | p.Q257L | 380 | Q294L |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-19-5956-01A | 5-gene | p.E236K | 380 | E273K |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-33-AAS8-01A | 5-gene | p.G14S | 380 | G51S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-49-AAR2-01A | 5-gene | p.K228Q | 380 | K265Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-49-AARE-01A | 5-gene | p.W210C | 380 | W247C |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-66-2770-01A | 5-gene | p.N92T | 380 | N129T |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-69-A59K-01A | 5-gene | p.W210C | 380 | W247C |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-77-7141-01A | 5-gene | p.K94N | 380 | K131N |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-77-8008-01A | 5-gene | p.D189Y | 380 | D226Y |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-78-7155-01A | 5-gene | p.V246F | 380 | V283F |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-A4-A48D-01A | 5-gene | p.K115E | 380 | K152E |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-A5-A0G2-01A | 5-gene | p.S213I | 380 | S250I |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-A5-A0GP-01A | 5-gene | p.S269N | 380 | S306N |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AA-3984-01A | 5-gene | p.E212D | 380 | E249D |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EK-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EL-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AJ-A5DW-01A | 5-gene | p.E124D | 380 | E161D |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AP-A0LM-01A | 5-gene | p.K94N | 380 | K131N |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AX-A063-01A | 5-gene | p.R172Q | 380 | R209Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AX-A0J0-01A | 5-gene | p.R331Q | 380 | R368Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AX-A2HD-01A | 5-gene | p.R331Q | 380 | R368Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-AZ-4615-01A | 5-gene | p.V298I | 380 | V335I |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-B5-A1MX-01A | 5-gene | p.P88H | 380 | P125H |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-B5-A3FC-01A | 5-gene | p.A105T;p.E127G | 380 | A142T;E164G |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-BP-5008-01A | 5-gene | p.N283K | 380 | N320K |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-BR-6452-01A | 5-gene | p.L196M | 380 | L233M |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-CI-6624-01C | 5-gene | p.S293F | 380 | S330F |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-CN-5369-01A | 5-gene | p.S103L | 380 | S140L |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-CR-7364-01A | 5-gene | p.G166R | 380 | G203R |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-CV-7090-01A | 5-gene | p.A294V | 380 | A331V |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-D1-A16X-01A | 5-gene | p.K233Q | 380 | K270Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-D3-A2JO-06A | 5-gene | p.G40S | 380 | G77S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-DD-AACF-01A | 5-gene | p.F179S | 380 | F216S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-DF-A2KU-01A | 5-gene | p.D287N | 380 | D324N |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-DK-A3WW-01A | 5-gene | p.V295L | 380 | V332L |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-DQ-5629-01A | 5-gene | p.A12V | 380 | A49V |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-EE-A184-06A | 5-gene | p.R65M | 380 | R102M |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-EO-A22R-01A | 5-gene | p.R172Q | 380 | R209Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-ER-A19G-06A | 5-gene | p.E55D | 380 | E92D |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-EY-A1G7-01A | 5-gene | p.K74R | 380 | K111R |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-F5-6814-01A | 5-gene | p.K318Q | 380 | K355Q |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-FJ-A3ZE-01A | 5-gene | p.P88S | 380 | P125S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-FW-A3R5-06A | 5-gene | p.P50S | 380 | P87S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-IB-7651-01A | 5-gene | p.A104S | 380 | A141S |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-L5-A88Y-01A | 5-gene | p.A314P | 380 | A351P |
| ENST00000400319_ENST00000395939_60582677_53266953 | TCGA-VS-A94X-01A | 5-gene | p.S175L | 380 | S212L |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-06-5416-01A | 5-gene | p.R262I | 273 | R192I |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-17-Z055-01A | 5-gene | p.R200Q | 273 | R130Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-18-3414-01A | 5-gene | p.Q257L | 273 | Q187L |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-19-5956-01A | 5-gene | p.E236K | 273 | E166K |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-33-AAS8-01A | 5-gene | p.G14S | 273 | G14S |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-49-AAR2-01A | 5-gene | p.K228Q | 273 | K158Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-49-AARE-01A | 5-gene | p.W210C | 273 | W140C |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-69-A59K-01A | 5-gene | p.W210C | 273 | W140C |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-77-8008-01A | 5-gene | p.D189Y | 273 | D119Y |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-78-7155-01A | 5-gene | p.V246F | 273 | V176F |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-A5-A0G2-01A | 5-gene | p.S213I | 273 | S143I |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-A5-A0GP-01A | 5-gene | p.S269N | 273 | S199N |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AA-3984-01A | 5-gene | p.E212D | 273 | E142D |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EK-01A | 5-gene | p.R262I | 273 | R192I |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EL-01A | 5-gene | p.R262I | 273 | R192I |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AX-A063-01A | 5-gene | p.R172Q | 273 | R102Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AX-A0J0-01A | 5-gene | p.R331Q | 273 | R261Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AX-A2HD-01A | 5-gene | p.R331Q | 273 | R261Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-AZ-4615-01A | 5-gene | p.V298I | 273 | V228I |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-BP-5008-01A | 5-gene | p.N283K | 273 | N213K |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-BR-6452-01A | 5-gene | p.L196M | 273 | L126M |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-CI-6624-01C | 5-gene | p.S293F | 273 | S223F |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-CR-7364-01A | 5-gene | p.G166R | 273 | G96R |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-CV-7090-01A | 5-gene | p.A294V | 273 | A224V |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-D1-A16X-01A | 5-gene | p.K233Q | 273 | K163Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-D3-A2JO-06A | 5-gene | p.G40S | 273 | G40S |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-DD-AACF-01A | 5-gene | p.F179S | 273 | F109S |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-DF-A2KU-01A | 5-gene | p.D287N | 273 | D217N |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-DK-A3WW-01A | 5-gene | p.V295L | 273 | V225L |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-DQ-5629-01A | 5-gene | p.A12V | 273 | A12V |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-EO-A22R-01A | 5-gene | p.R172Q | 273 | R102Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-ER-A19G-06A | 5-gene | p.E55D | 273 | E55D |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-F5-6814-01A | 5-gene | p.K318Q | 273 | K248Q |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-FW-A3R5-06A | 5-gene | p.P50S | 273 | P50S |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-L5-A88Y-01A | 5-gene | p.A314P | 273 | A244P |
| ENST00000400320_ENST00000395939_60582677_53266953 | TCGA-VS-A94X-01A | 5-gene | p.S175L | 273 | S105L |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-06-5412-01A | 5-gene | p.N112K | 380 | N149K |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-06-5416-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-17-Z055-01A | 5-gene | p.R200Q | 380 | R237Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-18-3414-01A | 5-gene | p.Q257L | 380 | Q294L |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-19-5956-01A | 5-gene | p.E236K | 380 | E273K |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-33-AAS8-01A | 5-gene | p.G14S | 380 | G51S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-49-AAR2-01A | 5-gene | p.K228Q | 380 | K265Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-49-AARE-01A | 5-gene | p.W210C | 380 | W247C |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-66-2770-01A | 5-gene | p.N92T | 380 | N129T |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-69-A59K-01A | 5-gene | p.W210C | 380 | W247C |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-77-7141-01A | 5-gene | p.K94N | 380 | K131N |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-77-8008-01A | 5-gene | p.D189Y | 380 | D226Y |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-78-7155-01A | 5-gene | p.V246F | 380 | V283F |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-A4-A48D-01A | 5-gene | p.K115E | 380 | K152E |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-A5-A0G2-01A | 5-gene | p.S213I | 380 | S250I |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-A5-A0GP-01A | 5-gene | p.S269N | 380 | S306N |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AA-3984-01A | 5-gene | p.E212D | 380 | E249D |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EK-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AJ-A3EL-01A | 5-gene | p.R262I | 380 | R299I |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AJ-A5DW-01A | 5-gene | p.E124D | 380 | E161D |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AP-A0LM-01A | 5-gene | p.K94N | 380 | K131N |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AX-A063-01A | 5-gene | p.R172Q | 380 | R209Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AX-A0J0-01A | 5-gene | p.R331Q | 380 | R368Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AX-A2HD-01A | 5-gene | p.R331Q | 380 | R368Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-AZ-4615-01A | 5-gene | p.V298I | 380 | V335I |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-B5-A1MX-01A | 5-gene | p.P88H | 380 | P125H |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-B5-A3FC-01A | 5-gene | p.A105T;p.E127G | 380 | A142T;E164G |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-BP-5008-01A | 5-gene | p.N283K | 380 | N320K |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-BR-6452-01A | 5-gene | p.L196M | 380 | L233M |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-CI-6624-01C | 5-gene | p.S293F | 380 | S330F |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-CN-5369-01A | 5-gene | p.S103L | 380 | S140L |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-CR-7364-01A | 5-gene | p.G166R | 380 | G203R |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-CV-7090-01A | 5-gene | p.A294V | 380 | A331V |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-D1-A16X-01A | 5-gene | p.K233Q | 380 | K270Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-D3-A2JO-06A | 5-gene | p.G40S | 380 | G77S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-DD-AACF-01A | 5-gene | p.F179S | 380 | F216S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-DF-A2KU-01A | 5-gene | p.D287N | 380 | D324N |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-DK-A3WW-01A | 5-gene | p.V295L | 380 | V332L |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-DQ-5629-01A | 5-gene | p.A12V | 380 | A49V |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-EE-A184-06A | 5-gene | p.R65M | 380 | R102M |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-EO-A22R-01A | 5-gene | p.R172Q | 380 | R209Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-ER-A19G-06A | 5-gene | p.E55D | 380 | E92D |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-EY-A1G7-01A | 5-gene | p.K74R | 380 | K111R |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-F5-6814-01A | 5-gene | p.K318Q | 380 | K355Q |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-FJ-A3ZE-01A | 5-gene | p.P88S | 380 | P125S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-FW-A3R5-06A | 5-gene | p.P50S | 380 | P87S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-IB-7651-01A | 5-gene | p.A104S | 380 | A141S |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-L5-A88Y-01A | 5-gene | p.A314P | 380 | A351P |
| ENST00000400330_ENST00000395939_60582677_53266953 | TCGA-VS-A94X-01A | 5-gene | p.S175L | 380 | S212L |
| CCLE All Mutated Fusion Protein Sequences |
| Fusion Protein ID | Sample ID | Mutated Partner | AAchange in WT | Seq. Length | AAchange in Fusion |
Top |
Fusion Gene Exprssed Samples for DIAPH3_DOK5 |
| RNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB | PRAD | TCGA-KK-A59V-01A | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 53266953 | + | |
| ChimerDB | PRAD | TCGA-KK-A59V | DIAPH3 | chr13 | 60582677 | - | DOK5 | chr20 | 60582677 | + |
| DNA-seq based fusion gene expressed samples. |
| Source | Study | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | SV type |
Top |
Related Drugs for DIAPH3_DOK5 |
| PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug'] * For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub. |
| PMID | Fusion Gene Name | Drug | Study Title |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies