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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:CAPZB_TMCO4 (FusionGDB2 ID:HG832TG255104)

Fusion Gene Summary for CAPZB_TMCO4

Fusion gene summary

Fusion gene information	Fusion gene name: CAPZB_TMCO4
	Fusion gene ID: hg832tg255104
		Hgene	Tgene
	Gene symbol	CAPZB	TMCO4
	Gene ID	832	255104
	Gene name	capping actin protein of muscle Z-line subunit beta	transmembrane and coiled-coil domains 4
	Synonyms	CAPB\|CAPPB\|CAPZ	-
	Cytomap	1p36.13	1p36.13
	Type of gene	protein-coding	protein-coding
	Description	F-actin-capping protein subunit betacapZ betacapping actin protein of muscle Z-line beta subunitcapping protein (actin filament) muscle Z-line, betaepididymis secretory sperm binding protein	transmembrane and coiled-coil domain-containing protein 4
	Modification date	20240407	20240403
	UniProtAcc	P47756	.
	Ensembl transtripts involved in fusion gene	ENST00000264202, ENST00000264203, ENST00000375142, ENST00000375144, ENST00000401084, ENST00000433834, ENST00000482808,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 32 X 27 X 23=19872	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 6 X 11 X 12=792
	# samples	56	30
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(56/1987210)=-5.14916644127551 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(30/79210)=-1.40053792958373 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CAPZB [Title/Abstract] AND TMCO4 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CAPZB(19811929)-TMCO4(20027378), # samples:3

Fusion gene breakpoints across CAPZB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TMCO4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for CAPZB_TMCO4

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
CAPZB	chr1	19746155	TMCO4	chr1	20027378
CAPZB	chr1	19811929	TMCO4	chr1	20009937
CAPZB	chr1	19811929	TMCO4	chr1	20027378
CAPZB	chr1	19711998	TMCO4	chr1	20027378
CAPZB	chr1	19811929	TMCO4	chr1	20021044
CAPZB	chr1	19810683	TMCO4	chr1	20027378
CAPZB	chr1	19811930	TMCO4	chr1	20009937
CAPZB	chr1	19811930	TMCO4	chr1	20027378
CAPZB	chr1	19711999	TMCO4	chr1	20027378
CAPZB	chr1	19485436	TMCO4	chr1	19694551
CAPZB	chr1	19485436	TMCO4	chr1	19700885
CAPZB	chr1	19385505	TMCO4	chr1	19700885

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	SV type
CAPZB	chr1	19809464	TMCO4	chr1	20123500	DUP

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for CAPZB_TMCO4

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CAPZB P47756	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

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Fusion Genomic Features for CAPZB_TMCO4

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-	3.72e-09	1.00e+00
CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-	3.12e-09	1.00e+00
CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-	2.12e-06	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-	2.07e-14	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-	1.69e-12	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-	4.02e-12	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-	3.72e-09	1.00e+00
CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-	3.12e-09	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-	2.07e-14	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-	1.69e-12	1.00e+00
CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-	4.02e-12	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for CAPZB_TMCO4

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000264202	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264202	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264202	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000264202	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000264202	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264202	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264202	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264202	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000264202	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000264202	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264203	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264203	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264203	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000264203	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000375142	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000375142	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375142	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000375142	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000375142	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375144	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375144	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375144	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000375144	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000401084	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000401084	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000401084	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5CDS-5UTR	ENST00000401084	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5CDS-5UTR	ENST00000401084	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000375122	CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5CDS-5UTR	ENST00000433834	ENST00000489814	CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-3CDS	ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-3CDS	ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-3CDS	ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-3CDS	ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-3CDS	ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-3CDS	ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5UTR-3CDS	ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-3CDS	ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-3CDS	ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000264203	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-5UTR	ENST00000264203	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-5UTR	ENST00000264203	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000264203	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-5UTR	ENST00000264203	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-5UTR	ENST00000264203	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000375122	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000375122	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-5UTR	ENST00000482808	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-5UTR	ENST00000482808	ENST00000375122	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000489814	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000489814	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
5UTR-5UTR	ENST00000482808	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
5UTR-5UTR	ENST00000482808	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
5UTR-5UTR	ENST00000482808	ENST00000489814	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
Frame-shift	ENST00000264202	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000264202	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264202	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000264202	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264203	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264203	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264203	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000264203	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
Frame-shift	ENST00000375142	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000375142	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375142	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000375142	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375144	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375144	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375144	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000375144	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
Frame-shift	ENST00000401084	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000401084	ENST00000294543	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000401084	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
Frame-shift	ENST00000401084	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000294543	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000294543	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000294543	CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000375127	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000375127	CAPZB	chr1	19746154	-	TMCO4	chr1	20027378	-
Frame-shift	ENST00000433834	ENST00000375127	CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-
In-frame	ENST00000264202	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
In-frame	ENST00000375142	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
In-frame	ENST00000401084	ENST00000375127	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000264202	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	52	142
ENST00000375142	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	50	142
ENST00000401084	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	137	1676

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0	203
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0	236
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0	236
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0	289
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0	143
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0	142
ENST00000482808	ENST00000294543	CAPZB	chr1	19711998	TMCO4	chr1	20027378	0	1594
ENST00000482808	ENST00000294543	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0	220
ENST00000482808	ENST00000294543	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0	236
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0	236
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0	236
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0	236
ENST00000482808	ENST00000375127	CAPZB	chr1	19711998	TMCO4	chr1	20027378	0	289
ENST00000482808	ENST00000375127	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0	149
ENST00000482808	ENST00000375127	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0	236
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0	149
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0	143
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0	142

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000264202	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	8.97e-01	1.03e-01
ENST00000375142	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	8.94e-01	1.06e-01
ENST00000401084	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	8.63e-01	1.37e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0.00e+00	6.79e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0.00e+00	4.41e-01
ENST00000482808	ENST00000294543	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0.00e+00	5.64e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0.00e+00	4.41e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0.00e+00	8.46e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0.00e+00	9.64e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0.00e+00	4.41e-01
ENST00000482808	ENST00000375127	CAPZB	chr1	19711998	TMCO4	chr1	20027378	0.00e+00	4.41e-01
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0.00e+00	5.64e-01
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0.00e+00	8.00e-01
ENST00000482808	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0.00e+00	8.00e-01
ENST00000482808	ENST00000294543	CAPZB	chr1	19746154	TMCO4	chr1	20027378	0.00e+00	5.64e-01
ENST00000482808	ENST00000294543	CAPZB	chr1	19711998	TMCO4	chr1	20027378	0.00e+00	5.64e-01
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0.00e+00	4.41e-01
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0.00e+00	8.46e-01
ENST00000264203	ENST00000375127	CAPZB	chr1	19811929	TMCO4	chr1	20009937	0.00e+00	9.64e-01
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20027378	0.00e+00	5.64e-01
ENST00000264203	ENST00000294543	CAPZB	chr1	19811929	TMCO4	chr1	20021044	0.00e+00	6.79e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

Top

Fusion Protein Retained/Non-Retained Functional Features for CAPZB_TMCO4

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Fusion Transcript Sequence for CAPZB_TMCO4

In-frame Fusion Transcript Sequences.

>CAPZB_TMCO4_ENST00000264202_ENST00000375127_19811929_20009937 length=684nt 
 Breakpoint=52nt
GGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCT
GGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCA
GGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCAT
GTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGG
GACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000375142_ENST00000375127_19811929_20009937 length=682nt 
 Breakpoint=50nt
GGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGG
CCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGG
TGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGT
AGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGA
CAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000401084_ENST00000375127_19811929_20009937 length=769nt 
 Breakpoint=137nt
GCCCGGCGCGGGGGGAGGGGGGTGCTGACCCGGATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTCAGCGGCCACC
TGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGG
AGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTG
GCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCC
CGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAA
TAAATAATAATAAGAAGAA

N-Truncated Transcript (5UTR-3CDS) Sequences

>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20009937 length=1232nt 
 Breakpoint=0nt
GTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCC
TCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCAAATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCC
AGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATTGTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAG
CTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCTTTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGA
AGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAGTCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCA
TCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCA
GGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATC
TGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAG
AAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20021044 length=1350nt 
 Breakpoint=0nt
GGGAGACTGGCTGCTGAGTTTCGTGTACCGCACATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGAT
GGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCA
AACCCAGGGTCCCATATCCGGAGACACCTCCAAATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGG
CATGGACCCCAACCCACTGGGCTGCCCCGATTGTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGA
GCTCTGGAGGTACAGGATTTCCACAGGCCTCTTTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGG
AGCAGCTGCCCCCTCATCAGAGACCTGCAGAGTCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGA
GGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTG
CTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACAT
GCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA


>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20027378 length=1468nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCA
AATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATT
GTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCT
TTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAG
TCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAAT
AAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTA
CAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAG
GCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20009937 length=632nt 
 Breakpoint=0nt
GTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCC
TCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAG
GCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGT
GAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGG
ATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20021044 length=750nt 
 Breakpoint=0nt
GGGAGACTGGCTGCTGAGTTTCGTGTACCGCACATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGAT
GGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGG
AGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGC
AGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGAC
ACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA


>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20027378 length=868nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTC
CCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTT
AGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGA
ATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19711998_20027378 length=1468nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCA
AATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATT
GTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCT
TTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAG
TCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAAT
AAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTA
CAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAG
GCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19746154_20027378 length=1468nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCA
AATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATT
GTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCT
TTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAG
TCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAAT
AAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTA
CAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAG
GCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20009937 length=1232nt 
 Breakpoint=0nt
GTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCC
TCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCAAATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCC
AGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATTGTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAG
CTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCTTTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGA
AGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAGTCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCA
TCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCA
GGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATC
TGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAG
AAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20021044 length=1350nt 
 Breakpoint=0nt
GGGAGACTGGCTGCTGAGTTTCGTGTACCGCACATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGAT
GGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCA
AACCCAGGGTCCCATATCCGGAGACACCTCCAAATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGG
CATGGACCCCAACCCACTGGGCTGCCCCGATTGTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGA
GCTCTGGAGGTACAGGATTTCCACAGGCCTCTTTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGG
AGCAGCTGCCCCCTCATCAGAGACCTGCAGAGTCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGA
GGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTG
CTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACAT
GCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA


>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20027378 length=1468nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCA
AATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATT
GTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCT
TTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAG
TCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAAT
AAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTA
CAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAG
GCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19711998_20027378 length=868nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTC
CCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTT
AGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGA
ATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19746154_20027378 length=868nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTC
CCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTT
AGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGA
ATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20009937 length=632nt 
 Breakpoint=0nt
GTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCC
TCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAG
GCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGT
GAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGG
ATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20021044 length=750nt 
 Breakpoint=0nt
GGGAGACTGGCTGCTGAGTTTCGTGTACCGCACATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGAT
GGATGCCATCCTGAAGGCCGTGGGCATCCGCACCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGG
AGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGC
AGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGAC
ACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA


>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20027378 length=868nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTC
CCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTT
AGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGA
ATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19746154_20027378 length=1468nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGGCGAGACCCCCCACCAGGTTGGGCAAACCCAGGGTCCCATATCCGGAGACACCTCCA
AATTGGCCATGTCCACAGACCCCAGCCAAGCCCAGGTGCCAGTAGGGCTGGACCAGTCTGAAGGGGCCTCCCTTCCTGCTGCTGCCAGCCCTGAAAGGCCCCCCATCTGCAGCCATGGCATGGACCCCAACCCACTGGGCTGCCCCGATT
GTGCCTGCAAGACCCAGGGCCCCAGCACGGGGCTGGACTGACCACAGCAGGGGACCTGAGCCGTCTTCCCCAGTCTCCATATGCAGCTCTCTCTTATACCCTCGGGTTCCTCCCAGGAGCTCTGGAGGTACAGGATTTCCACAGGCCTCT
TTCCTAAATGGAAGGAATTGGAACTGAAAGGGAAAGGAAATGGAAGGAAGGGGAATTTGGAGGAGAGAACACGCCCACCCTTGGGAAGCTGCCTGTCCCCAGAGGAGCCCCACCAGGGAGCAGCTGCCCCCTCATCAGAGACCTGCAGAG
TCAACCAAGCACAGGTTAGAGTCCCAGGACCGGAAACCAACTGTGGGCTTTCTGTACTTCTCATAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTCCCACACCAGCTCTCCCCTGGCCTCAAT
AAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTTAGGAGATCCAATCAGATCTGCCCTGTA
CAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGAATTGCATTCAGTATGGCTGTGAACTAG
GCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAAGCTACCACTTCTTGAGCATGTACCACA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19746154_20027378 length=868nt 
 Breakpoint=0nt
ATTGCCAAGGAATCATCGAGGACGTCATCCTGCTGGGTGCGCCTGTGGAGGGAGAAGCCAAGCATTGGGAGCCTTTCCGGAAGGTGGTGTCCGGGAGGATCATCAACGGCTACTGCAGGGGAGACTGGCTGCTGAGTTTCGTGTACCGCA
CATCCTCGGTGCAGCTCCGTGTCGCCGGCCTACAGCCCGTGCTGCTGCAGGACAGGAGGGTGGAGAACGTGGACCTGACCTCTGTGGTCAGCGGCCACCTGGACTATGCCAAGCAGATGGATGCCATCCTGAAGGCCGTGGGCATCCGCA
CCAAGCCAGGCTGGGACGAGAAGGGGCTCTTGCTGGCCCCAGGCTGCCTGCCCTCCGAGGAGCCTCGCCAGGCAGCAGCTGCCGCCTCATCAGCTTTGGAGTCTGGCTGTCCATCAGGAGGTCCCGAGGGCTCTCTGGGGCCTGAGGCTC
CCACACCAGCTCTCCCCTGGCCTCAATAAAACCAGGTGCATGCCTGTTCTTCCATCCACACTCCAGGGCTGCCCACCAGCTGACAGGCACCATCAACTGGCAGCAACAGAGCAGGCGCAGGTACAAAGAAGGCAGCTCACTCCTGCTCTT
AGGAGATCCAATCAGATCTGCCCTGTACAGCCATGTAGGCTGTGCGCTGCATAACTCCAGGGACATGAGTCACACAGACACAATGTGAGTGTGCTCCCCCGTCATGCAACATCTGGACACCACTAACAGAGCATGGTGAATACATGCTGA
ATTGCATTCAGTATGGCTGTGAACTAGGCCTGGGGACAAGAATGAATTTTACATGGAAAGAATTTCCTGTAGCAGGAACAGAGGGGATAACAACAGCAATAAATAATAATAAGAAGAA

C-Truncated Transcript (5CDS-3UTR) Sequences

Top

Fusion Protein Sequence for CAPZB_TMCO4

In-frame Fusion Protein Sequences.

>CAPZB_TMCO4_ENST00000264202_ENST00000375127_19811929_20009937 length=142nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGR

>CAPZB_TMCO4_ENST00000375142_ENST00000375127_19811929_20009937 length=142nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGR

>CAPZB_TMCO4_ENST00000401084_ENST00000375127_19811929_20009937 length=1676nt
MDCALDLMRRLPPQQIEKNLSDLIDLVTQVARQPGTPTPSPYSAHEINKGHPNLAATPPGHASSPGLSQTPYPSGQNAGPTTLVYPQTPQTMNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYP
VPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTP
VTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI
NGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTW
KKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQP
KLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSVKEDVHLKKAENAWKPSQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAY
ANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI
VKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPAP
SGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFV
RVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDS
PCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQN
GKGVALKSVTAFFTWLREAEEESEDN

N-Truncated Protein (5UTR-3CDS) Sequences

>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20009937 length=203nt
MQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLE
GNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQAVSTATLIVIEPST

>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20021044 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000264203_ENST00000294543_19811929_20027378 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20009937 length=289nt
MQNQVNVNPERANPVTDPVSMAAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSNSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIVTVQDGQQVL
TVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGELEERETKVTGSAGTTEPHTRVSMATVSS

>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20021044 length=143nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGRX

>CAPZB_TMCO4_ENST00000264203_ENST00000375127_19811929_20027378 length=142nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGR

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19711998_20027378 length=1594nt
MVYPQTPQTMNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPNAYGTPFYPSQPVYQSAPIIVPTQQQPPPAKREKKT
IRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQP
IFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAPITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSS
PSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGID
ANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPRGPDFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIITVSVKEDVHLKKAENAWKPSQKRDS
QADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIG
NIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTKEKRRPGVQRVDEGGWNTVQGA
KNSRVLDPSKFLKITKPTIDEKIQLVPKAQLGSWGKGSSGGAKASETDALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNST
EAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIE
FSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQ
RVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19746154_20027378 length=220nt
LLERPVLLPPVSIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQYMHTDVPER
DLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWHQDQVAAGLLPNPPESAPE

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19746154_20027378 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20009937 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20021044 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000482808_ENST00000294543_19811929_20027378 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19711998_20027378 length=289nt
MQNQVNVNPERANPVTDPVSMAAPFIFTSGEVVNLASLISSTNTKTTSGDPHASTVQFSNSTTSVLATLAALAEASVPLSNSHRATANTEEIIEGNSVDSSIQQVMGSGGQRVITIVTDGVPLGNIQTSIPTGGIGQPFIVTVQDGQQVL
TVPAGKVAEETVIKEEEEEKLPLTKKPRIGEKTNSVEESKEGNERELLQQQLQEANRRAQEYRHQLLKKEQEAEQYRLKLEAIARQQPNGVDFTMVEEVAEVDAVVVTEGELEERETKVTGSAGTTEPHTRVSMATVSS

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19746154_20027378 length=149nt
MLGAPVEGEAKHWEPFRKVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRVENVDLTSVVSGHLDYAKQMDAILKAVGIRTKPGWDEKGLLLAPGCLPSEEPRQAAAAASSALESGCPSGGPEGSLGPEAPTPALPWPQ

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19746154_20027378 length=236nt
MRSTESPQLVSGPGTLTCAWLTLQVSDEGAAAPWWGSSGDRQLPKGGRVLSSKFPFLPFPFPFSSNSFHLGKRPVEILYLQSSWEEPEGIRESCIWRLGKTAQVPCCGQSSPVLGPWVLQAQSGQPSGLGSMPWLQMGGLSGLAAAGREA
PSDWSSPTGTWAWLGSVDMANLEVSPDMGPWVCPTWWGVSPDEAAAAAWRGSSEGRQPGASKSPFSSQPGLVRMPTAFRMASICLA

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20009937 length=149nt
MLGAPVEGEAKHWEPFRKVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRVENVDLTSVVSGHLDYAKQMDAILKAVGIRTKPGWDEKGLLLAPGCLPSEEPRQAAAAASSALESGCPSGGPEGSLGPEAPTPALPWPQ

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20021044 length=143nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGRX

>CAPZB_TMCO4_ENST00000482808_ENST00000375127_19811929_20027378 length=142nt
MSLELCSAQPTWLYRADLIGSPKSRSELPSLYLRLLCCCQLMVPVSWWAALECGWKNRHAPGFIEARGELVWEPQAPESPRDLLMDSQTPKLMRRQLLPGEAPRRAGSLGPARAPSRPSLAWCGCPRPSGWHPSAWHSPGGR

C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for CAPZB_TMCO4

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for CAPZB_TMCO4

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
CCLE		Colon Adenocarcinoma	GP2D	CAPZB	chr1	19746155	-	TMCO4	chr1	20027378	-
ChimerDB		OV	TCGA-13-1506-01A	CAPZB	chr1	19811929	-	TMCO4	chr1	20009937	-
ChimerDB		OV	TCGA-36-1581-01A	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
ChimerDB		STAD	TCGA-VQ-A922-01A	CAPZB	chr1	19711998	-	TMCO4	chr1	20027378	-
ChimerDB		UCEC	TCGA-KP-A3VZ-01A	CAPZB	chr1	19811929	-	TMCO4	chr1	20021044	-
ChimerDB		UCS	TCGA-N7-A4Y8-01A	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
ChimerDB		UCS	TCGA-N7-A4Y8	CAPZB	chr1	19810683	-	TMCO4	chr1	20027378	-
ChimerDB		UCS	TCGA-N7-A4Y8	CAPZB	chr1	19811929	-	TMCO4	chr1	20027378	-
WashU		OV	TCGA-13-1506-01A	CAPZB	chr1	19811930	-	TMCO4	chr1	20009937	-
WashU		OV	TCGA-36-1581-01A	CAPZB	chr1	19811930	-	TMCO4	chr1	20027378	-
WashU		STAD	TCGA-VQ-A922-01A	CAPZB	chr1	19711999	-	TMCO4	chr1	20027378	-
WashU		UCS	TCGA-N7-A4Y8-01A	CAPZB	chr1	19811930	-	TMCO4	chr1	20027378	-
cBioPortal	CCLE_BROAD_2019	MIXED	GP2D_LARGE_INTESTINE	CAPZB	chr1	19746155		TMCO4	chr1	20027378
cBioPortal	UCEC_TCGA_PAN_CAN_ATLAS_2018	UCEC	TCGA-KP-A3VZ-01	CAPZB	chr1	19485436		TMCO4	chr1	19694551
cBioPortal	UCS_TCGA_PAN_CAN_ATLAS_2018	UCS	TCGA-N7-A4Y8-01	CAPZB	chr1	19485436		TMCO4	chr1	19700885
cBioPortal	STAD_TCGA_PAN_CAN_ATLAS_2018	STAD	TCGA-VQ-A922-01	CAPZB	chr1	19385505		TMCO4	chr1	19700885

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

dbVar

nstd102

Unknown_Cell

CAPZB

chr1

19809464

TMCO4

chr1

20123500

DUP

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Related Drugs for CAPZB_TMCO4

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status