Home

Download

Statistics

Examples

About

Contact

	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:ZCCHC7_SERINC3 (FusionGDB2 ID:HG84186TG10955)

Fusion Gene Summary for ZCCHC7_SERINC3

Fusion gene summary

Fusion gene information	Fusion gene name: ZCCHC7_SERINC3
	Fusion gene ID: hg84186tg10955
		Hgene	Tgene
	Gene symbol	ZCCHC7	SERINC3
	Gene ID	84186	10955
	Gene name	zinc finger CCHC-type containing 7	serine incorporator 3
	Synonyms	AIR1\|HSPC086	AIGP1\|DIFF33\|SBBI99\|TDE\|TDE1\|TMS-1
	Cytomap	9p13.2	20q13.12
	Type of gene	protein-coding	protein-coding
	Description	zinc finger CCHC domain-containing protein 7TRAMP-like complex RNA-binding factor ZCCHC7zinc finger, CCHC domain containing 7	serine incorporator 3tumor differentially expressed protein 1
	Modification date	20240411	20240305
	UniProtAcc	Q8N3Z6	Q13530
	Ensembl transtripts involved in fusion gene	ENST00000461038, ENST00000322831, ENST00000336755, ENST00000534928,	ENST00000461038, ENST00000534928, ENST00000322831, ENST00000336755,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 33 X 11 X 18=6534	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 3 X 9 X 4=108
	# samples	52	22
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(52/653410)=-3.65138292640961 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(22/10810)=1.02647221136119 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ZCCHC7 [Title/Abstract] AND SERINC3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ZCCHC7(37126939)-SERINC3(43135637), # samples:1

Top

Fusion Gene Breakpoints for ZCCHC7_SERINC3

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
ZCCHC7	chr9	37126939	SERINC3	chr20	43135637

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

Top

Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for ZCCHC7_SERINC3

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name

Mechanism Category

Mechanism PubMed

Tumorigenic Scenarios

Tumorigenic Scenario PubMed

Targeting Points

Targeting PubMed

Mechanism Background

Mechanism Background PubMed

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ZCCHC7 Q8N3Z6	SERINC3 Q13530

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	SERINC3	GO:0009597	detection of virus	26416733\|26416734
Tgene	SERINC3	GO:0045087	innate immune response	26416733\|26416734
Tgene	SERINC3	GO:0051607	defense response to virus	26416733\|26416734

Top

Fusion Genomic Features for ZCCHC7_SERINC3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-	8.08e-07	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

Top

Fusion Gene ORF Annotations for ZCCHC7_SERINC3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000461038	ENST00000255175	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
3UTR-3CDS	ENST00000461038	ENST00000342374	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
3UTR-3CDS	ENST00000461038	ENST00000541235	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000322831	ENST00000255175	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000322831	ENST00000342374	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000322831	ENST00000541235	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000336755	ENST00000255175	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000336755	ENST00000342374	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-
In-frame	ENST00000336755	ENST00000541235	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000322831	ENST00000255175	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	876	472
ENST00000322831	ENST00000342374	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	876	472
ENST00000322831	ENST00000541235	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	876	472
ENST00000336755	ENST00000255175	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	716	195
ENST00000336755	ENST00000342374	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	716	472
ENST00000336755	ENST00000541235	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	716	472

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000322831	ENST00000255175	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	5.65e-04	9.99e-01
ENST00000322831	ENST00000342374	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	9.93e-04	9.99e-01
ENST00000322831	ENST00000541235	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	5.53e-04	9.99e-01
ENST00000336755	ENST00000255175	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	9.71e-04	9.99e-01
ENST00000336755	ENST00000342374	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	1.13e-03	9.99e-01
ENST00000336755	ENST00000541235	ZCCHC7	chr9	37126939	SERINC3	chr20	43135637	9.48e-04	9.99e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

Top

Fusion Protein Retained/Non-Retained Functional Features for ZCCHC7_SERINC3

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Fusion Transcript Sequence for ZCCHC7_SERINC3

In-frame Fusion Transcript Sequences.

>ZCCHC7_SERINC3_ENST00000322831_ENST00000255175_37126939_43135637 length=1855nt 
 Breakpoint=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCCGGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCAC
TCGTGGCAGGGCGCAGCTCCTGGAGAATCTGAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCAT
ACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAG
CACAAGAAAATGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAG
AGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCT
TTTATATCCTGTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAAC
ACCAGCCTCGCTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTC
CTGGAAATTCAACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACA
AGCTGACCCTGTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCT
GCTTGGCTTCCTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGG
CTCCACTTGTCCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGCACCCAACTCAGTGATGTCCTAATTACTGCTGGATGACTCAAGCCACACCATGCCTATGTTCTCAGGTGAAGAAGA
ATAATAGAAACCACATAGATGGGTAGGTGTACCAAGCATTAAACAGACAGTATCC

>ZCCHC7_SERINC3_ENST00000322831_ENST00000342374_37126939_43135637 length=4550nt 
 Breakpoint=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCCGGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCAC
TCGTGGCAGGGCGCAGCTCCTGGAGAATCTGAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCAT
ACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAG
CACAAGAAAATGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAG
AGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCT
TTTATATCCTGTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAAC
ACCAGCCTCGCTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTC
CTGGAAATTCAACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACA
AGCTGACCCTGTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCT
GCTTGGCTTCCTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGG
CTCCACTTGTCCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGTCTCCTTCACCGAAAACCCATATACCTTTTAAGTTTGTTTCAACTAAAATATTAAGTGAATGCTTTGCAAGTTTGA
CTGTATGCAGGTTTATATCAGAAGGTGAGATTGAATAATGCTTGATGCAGAATCGAAACTTCTCATTTATCTGTATATTATGTTTACTTCTAAGGATATAGCACAAAGGGAACATTTTTTGTTTAAAGTGAACTACAGCTGTGCTGTGAA
GAGAGTTCTTTATAAAGCCTGTAGGTTCTTTTAACTTTGGTTTAAAATGTAAGATAGGAAAATGTTGGATATTTGAGGCCATGCTTAATATATTTATATTGCAGTATCCTTTAAAAGCAAAAAAAAAAAAATGCATTTATATTACAGTTT
TCCTCTATGAAAGTCCTTACTTATATGATACAAGCACTGTGTTTTGTGCTTAAACTCTTCAGCGGGGTAGCATCAAAGTTCTTGGGGAAGGATCGTATATGTGGGTCCCTTCCCTAGAAGAATGGTTGCTGATATGGCTACTGCTTCTAC
ATCTTGAGTTTTTTAATTTACTTTTTTTACACTGTAGCATTGAGACTGCTTGATTCAAGTCTGGTGCTTTGCCAGATGTATTAATTTCCATAAATGCTTTGTGAGTTTGGTTAAAATGAAGATTCACTTGGGAAAACACTGCAGCTTTAG
TCTGTGTTACTATCTTGTTATGAGTATGTAAAAGTAAAATGCATGTGAATTTATCATATTTGCACTATGAAGGTATTTGGTTAAAATACAAAGACTTTTAAGATTTTAAGGCCCTTTCTTCCAACAGCTTTTATAGTTAGCAGCCATTCT
TTATTTTCTGGATAGCCAGGTTTTATCACGCTTCTAGTCAGGATGCTCCTATTCCTTCTAAAAATTACGGTCTGACTAGTGAGCAAAGTCTTGAATTTATTCAAAAGTCCTAAATACCTTCTCTAGGTAAGACACTTGGTAGATGAGAGA
CGGAAGGCATTGTCAAGAACCATTTTCATGAGAGGTGGTGTGCAAAAAGGTAGAATAAAAGAGTTCTTTCAACAAAGATTTACTGTCTATTCTGTACTAGACCCTGTAGGTTTTGGGGTACAGTGTTAAACATGATAGAGGCTCTGCCGT
CTTGGACTTTAATAGCTTAGAGAAGAGAGCAAATGAGCTGACAGGTGGTTATAATGTGAATTAGTGCTGTGGTTTAGGAATTGGAGAGAACTCAAAGGAGAGGTATTTGGTGTAATGGTAGGCTTTCTGGAGAAAATGATATTTAAGCCA
AGAACTCTTAGAAGTTAGCTAAGAGAGAGATGGGAAAATGAGACGACATTGCTGGAGTAGATAAAACTGCATGTTAAAGGCAGGAAGATGGGGAAAAAAAGTTCAGTAAAGCTGGAATGGGGAAATGTAGTCAGGGACTGAATTTTAAAG
GGCTTTATCAACCTCAGTAAAGAGTTTGGACCTTATGTTGAGGGTGGCTGAAAACATATTCATAGTGTCATGAACAAATTTTATCTTCAGTCACTTGGGCTGATATATAGAGAATGGATTTAGAGAGATGAGACCAGGTGCAGTCCATAT
GAGATGTGAAATAGAGAAGTGGAATCGTAGGGACGGGGAGAAATTGACAGGTGAGGGCTACTTAGCAATTAGAATTTTTTTTTTTCAATTTTAATTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATGGTGC
GATCTCCGCTCACTGCAGGCTCCGCCTCCCGGGTTCACGCCATTCTCCCGCCTCAGCCTCCCTAGTAGCTGGGACTACAGGCACCCACCACCACGCCTGGCTAATTTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCA
GGATGGTCTCGATCTCCTGACCTCGTGATCCACCTGCCGCGGCCTCCCAAAGTTCTAGGATTACTGGCATGAGCCACCGTGCCTGGCCAGCAATTAGAATTTTAACACTGGCAGTTATGAATAATATGAAGGAGAGGTAGATTTCTGAGT
GATTCTGGTTTAACCAGCTGGGTGGATGGTGGTTCCACGTATTCAGGTGGCAAACAGGAAAAACATGTGTTCGAAGAAGAATGGAGGTAGGTGGTCTCTTAAGAATGGTTAAGAGGCTTGGGAGTCAGACTGCTTGGGTTTGCATCCCAG
CTTTGCCGTTTTCTGGCTATCAAACTTGTCAGCTATTATTTGTTGAGTACGTACTATTTGATTTATGACCACAGGCAGCTGAGCCTCAGTGTTGGTGCCTAGTGTACAAGATTGTTAAAGAATAAAGTTATTTTGCAAAGTGTAACCCAT
TTTTAGCACTGACATAGCACTGACAGTAGCTGCTGATCTCATTATGGGCTAAAATAAGACAATATTCAAAGGTCAGAGATATCTAGCCAGAATCTGATGGAGGCTGGATTTCAGATTTTGTTACAGAATTAGACAGAGGAACACAGAGGG
GACAGGCTCAGTTAGGGTGGAGGTGTGGGGTAGGGAAGCAGGACTTGATATAAATTATTGGAATCATTGTCTTTTAAACCAGTGGTTTATGTCAGGGTATAGCGTTTCAAGGGATTTGAGGGTCAGATGGGGAAATGTAGCCCCTTATTT
TGCCAGTGTGAAGCAGATACCCTGCTTTTCTTTACAGTAGCGGAGTCAGCTTAAGAGCTTTAAAGGTCCTAAACTTCAAAAACATTACAGTGCCCCATCCTCCGCCTTAATGTAATTCAAAATACAAACAATACTAAACTGTAAAATAAA
TGTAACAAAGTCCAATAAAGTTTTTATTTTTTTCTCATGATGATAACTGA

>ZCCHC7_SERINC3_ENST00000322831_ENST00000541235_37126939_43135637 length=1809nt 
 Breakpoint=876nt
CCTGTTCGCAGCTGCGGCAGTGAGTATGTGTGTGACGGACCCCCGCCGCCCGCGGCTCGGGACCCCTGCCTACCCTCCTTCTTGCCCGCCGGGCTGTGGAACTAGCGCGTGCCCCCTCGCCGGCCTCGACGTCTCCCGTCCGCCCCTCAC
TCGTGGCAGGGCGCAGCTCCTGGAGAATCTGAGCATGGGGAATAAAGTCAGGAAGGATCGCAAGTGAGGATTATATTAATATGATAATTAGCACGCTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCAT
ACGAAGATGATCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATT
CGGAATCTTCGAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAG
CACAAGAAAATGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAG
AGGAAGAGAGCACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCT
TTTATATCCTGTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAAC
ACCAGCCTCGCTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTC
CTGGAAATTCAACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACA
AGCTGACCCTGTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCT
GCTTGGCTTCCTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGG
CTCCACTTGTCCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGTCTCCTTCACCGAAAACCCATATACCTTTTAAGTTTGTTTCAACTAAAATATTAAGTGAATGCTTTGCAAGTTTGA
CTGTATGCA

>ZCCHC7_SERINC3_ENST00000336755_ENST00000255175_37126939_43135637 length=1695nt 
 Breakpoint=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGA
TCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATTCGGAATCTTC
GAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAG
CACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCTTTTATATCCT
GTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAACACCAGCCTCG
CTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTCCTGGAAATTC
AACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACAAGCTGACCCT
GTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCTGCTTGGCTTC
CTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGGCTCCACTTGT
CCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGCACCCAACTCAGTGATGTCCTAATTACTGCTGGATGACTCAAGCCACACCATGCCTATGTTCTCAGGTGAAGAAGAATAATAGAAA
CCACATAGATGGGTAGGTGTACCAAGCATTAAACAGACAGTATCC

>ZCCHC7_SERINC3_ENST00000336755_ENST00000342374_37126939_43135637 length=4390nt 
 Breakpoint=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGA
TCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATTCGGAATCTTC
GAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAG
CACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCTTTTATATCCT
GTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAACACCAGCCTCG
CTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTCCTGGAAATTC
AACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACAAGCTGACCCT
GTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCTGCTTGGCTTC
CTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGGCTCCACTTGT
CCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGTCTCCTTCACCGAAAACCCATATACCTTTTAAGTTTGTTTCAACTAAAATATTAAGTGAATGCTTTGCAAGTTTGACTGTATGCAG
GTTTATATCAGAAGGTGAGATTGAATAATGCTTGATGCAGAATCGAAACTTCTCATTTATCTGTATATTATGTTTACTTCTAAGGATATAGCACAAAGGGAACATTTTTTGTTTAAAGTGAACTACAGCTGTGCTGTGAAGAGAGTTCTT
TATAAAGCCTGTAGGTTCTTTTAACTTTGGTTTAAAATGTAAGATAGGAAAATGTTGGATATTTGAGGCCATGCTTAATATATTTATATTGCAGTATCCTTTAAAAGCAAAAAAAAAAAAATGCATTTATATTACAGTTTTCCTCTATGA
AAGTCCTTACTTATATGATACAAGCACTGTGTTTTGTGCTTAAACTCTTCAGCGGGGTAGCATCAAAGTTCTTGGGGAAGGATCGTATATGTGGGTCCCTTCCCTAGAAGAATGGTTGCTGATATGGCTACTGCTTCTACATCTTGAGTT
TTTTAATTTACTTTTTTTACACTGTAGCATTGAGACTGCTTGATTCAAGTCTGGTGCTTTGCCAGATGTATTAATTTCCATAAATGCTTTGTGAGTTTGGTTAAAATGAAGATTCACTTGGGAAAACACTGCAGCTTTAGTCTGTGTTAC
TATCTTGTTATGAGTATGTAAAAGTAAAATGCATGTGAATTTATCATATTTGCACTATGAAGGTATTTGGTTAAAATACAAAGACTTTTAAGATTTTAAGGCCCTTTCTTCCAACAGCTTTTATAGTTAGCAGCCATTCTTTATTTTCTG
GATAGCCAGGTTTTATCACGCTTCTAGTCAGGATGCTCCTATTCCTTCTAAAAATTACGGTCTGACTAGTGAGCAAAGTCTTGAATTTATTCAAAAGTCCTAAATACCTTCTCTAGGTAAGACACTTGGTAGATGAGAGACGGAAGGCAT
TGTCAAGAACCATTTTCATGAGAGGTGGTGTGCAAAAAGGTAGAATAAAAGAGTTCTTTCAACAAAGATTTACTGTCTATTCTGTACTAGACCCTGTAGGTTTTGGGGTACAGTGTTAAACATGATAGAGGCTCTGCCGTCTTGGACTTT
AATAGCTTAGAGAAGAGAGCAAATGAGCTGACAGGTGGTTATAATGTGAATTAGTGCTGTGGTTTAGGAATTGGAGAGAACTCAAAGGAGAGGTATTTGGTGTAATGGTAGGCTTTCTGGAGAAAATGATATTTAAGCCAAGAACTCTTA
GAAGTTAGCTAAGAGAGAGATGGGAAAATGAGACGACATTGCTGGAGTAGATAAAACTGCATGTTAAAGGCAGGAAGATGGGGAAAAAAAGTTCAGTAAAGCTGGAATGGGGAAATGTAGTCAGGGACTGAATTTTAAAGGGCTTTATCA
ACCTCAGTAAAGAGTTTGGACCTTATGTTGAGGGTGGCTGAAAACATATTCATAGTGTCATGAACAAATTTTATCTTCAGTCACTTGGGCTGATATATAGAGAATGGATTTAGAGAGATGAGACCAGGTGCAGTCCATATGAGATGTGAA
ATAGAGAAGTGGAATCGTAGGGACGGGGAGAAATTGACAGGTGAGGGCTACTTAGCAATTAGAATTTTTTTTTTTCAATTTTAATTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAATGGTGCGATCTCCGCT
CACTGCAGGCTCCGCCTCCCGGGTTCACGCCATTCTCCCGCCTCAGCCTCCCTAGTAGCTGGGACTACAGGCACCCACCACCACGCCTGGCTAATTTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCAGGATGGTCTC
GATCTCCTGACCTCGTGATCCACCTGCCGCGGCCTCCCAAAGTTCTAGGATTACTGGCATGAGCCACCGTGCCTGGCCAGCAATTAGAATTTTAACACTGGCAGTTATGAATAATATGAAGGAGAGGTAGATTTCTGAGTGATTCTGGTT
TAACCAGCTGGGTGGATGGTGGTTCCACGTATTCAGGTGGCAAACAGGAAAAACATGTGTTCGAAGAAGAATGGAGGTAGGTGGTCTCTTAAGAATGGTTAAGAGGCTTGGGAGTCAGACTGCTTGGGTTTGCATCCCAGCTTTGCCGTT
TTCTGGCTATCAAACTTGTCAGCTATTATTTGTTGAGTACGTACTATTTGATTTATGACCACAGGCAGCTGAGCCTCAGTGTTGGTGCCTAGTGTACAAGATTGTTAAAGAATAAAGTTATTTTGCAAAGTGTAACCCATTTTTAGCACT
GACATAGCACTGACAGTAGCTGCTGATCTCATTATGGGCTAAAATAAGACAATATTCAAAGGTCAGAGATATCTAGCCAGAATCTGATGGAGGCTGGATTTCAGATTTTGTTACAGAATTAGACAGAGGAACACAGAGGGGACAGGCTCA
GTTAGGGTGGAGGTGTGGGGTAGGGAAGCAGGACTTGATATAAATTATTGGAATCATTGTCTTTTAAACCAGTGGTTTATGTCAGGGTATAGCGTTTCAAGGGATTTGAGGGTCAGATGGGGAAATGTAGCCCCTTATTTTGCCAGTGTG
AAGCAGATACCCTGCTTTTCTTTACAGTAGCGGAGTCAGCTTAAGAGCTTTAAAGGTCCTAAACTTCAAAAACATTACAGTGCCCCATCCTCCGCCTTAATGTAATTCAAAATACAAACAATACTAAACTGTAAAATAAATGTAACAAAG
TCCAATAAAGTTTTTATTTTTTTCTCATGATGATAACTGA

>ZCCHC7_SERINC3_ENST00000336755_ENST00000541235_37126939_43135637 length=1649nt 
 Breakpoint=716nt
CTCCTTACCTCATTTGTCCTCGCCCCTCCCCGTCCCTCTACGCGTTTTGGTTCCCGGTTGGTGCTTCCTGTTCGCAGCTGCGGCACTTCAAGGTTACTGACTTTTTATGATGTTTGGTGGCTATGAGACTATAGAAGCATACGAAGATGA
TCTTTATCGAGATGAGTCATCTAGTGAACTGAGTGTTGATAGTGAGGTGGAATTTCAACTCTATAGCCAAATTCATTATGCCCAAGATCTTGATGATGTCATCAGGGAGGAAGAGCATGAAGAAAAGAACTCTGGGAATTCGGAATCTTC
GAGTAGTAAACCAAATCAGAAGAAGCTAATCGTCCTTTCAGATAGTGAGGTCATCCAGCTGTCAGATGGGTCAGAGGTCATCACTTTGTCTGATGAAGACAGTATTTATAGATGTAAAGGAAAGAATGTTAGAGTTCAAGCACAAGAAAA
TGCCCATGGTCTTTCTTCTTCTCTTCAATCTAATGAGCTGGTTGATAAGAAATGCAAGAGTGATATTGAGAAGCCTAAATCTGAAGAGAGATCAGGTGTAATCCGAGAGGTCATGATTATAGAGGTCAGTTCAAGTGAAGAGGAAGAGAG
CACCATTTCAGAAGGTGATAATGTGGAAAGCTGGATGCTACTGGGATGTGAAGTAGATGATAAAGATGATGATATCCTTCTCAACCTTGTGGGATGTGAAAACTCTGTTACTGAAGCTTTACTGTCTTTCACAAGCGCCTTTTATATCCT
GTCAATCATCTGTGTCGGGCTGCTCTATACATATTACACCAAACCAGATGGCTGCACAGAAAACAAGTTCTTCATCAGTATTAACCTGATCCTTTGCGTTGTGGCTTCTATTATATCGATCCACCCAAAAATTCAGGAACACCAGCCTCG
CTCCGGCCTCTTGCAGTCCTCCCTCATCACCCTCTACACTATGTACCTCACCTGGTCAGCCATGTCCAATGAACCTGATCGTTCCTGCAATCCCAACCTGATGAGCTTTATTACACGCATAACTGCACCAACCCTGGCTCCTGGAAATTC
AACTGCTGTGGTCCCTACCCCTACTCCACCATCAAAGAGTGGGTCTTTACTGGATTCAGATAATTTTATTGGACTGTTTGTCTTTGTTCTCTGCCTCTTGTATTCTAGCATCCGCACTTCCACTAATAGCCAAGTAGACAAGCTGACCCT
GTCAGGGAGTGACAGCGTCATCCTTGGTGATACAACTACCAGTGGTGCCAGTGATGAAGAAGATGGACAGCCTCGGCGGGCTGTGGACAACGAGAAAGAGGGAGTGCAGTATAGCTACTCCTTATTCCACCTCATGCTCTGCTTGGCTTC
CTTGTACATCATGATGACCCTGACCAGCTGGTACAGCCCTGATGCAAAGTTTCAGAGCATGACCAGCAAGTGGCCAGCTGTGTGGGTCAAGATCAGCTCCAGCTGGGTCTGCCTCCTGCTTTACGTCTGGACCCTTGTGGCTCCACTTGT
CCTCACCAGTCGGGACTTCAGCTGAACCTCTGAGTGCCAAGGACACCACTGGAACTCACAAAGGTCTCCTTCACCGAAAACCCATATACCTTTTAAGTTTGTTTCAACTAAAATATTAAGTGAATGCTTTGCAAGTTTGACTGTATGCA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

Top

Fusion Protein Sequence for ZCCHC7_SERINC3

In-frame Fusion Protein Sequences.

>ZCCHC7_SERINC3_ENST00000322831_ENST00000255175_37126939_43135637 length=472nt
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIR
EVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMS
FITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSW
VCLLLYVWTLVAPLVLTSRDFS

>ZCCHC7_SERINC3_ENST00000322831_ENST00000342374_37126939_43135637 length=472nt
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIR
EVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMS
FITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSW
VCLLLYVWTLVAPLVLTSRDFS

>ZCCHC7_SERINC3_ENST00000322831_ENST00000541235_37126939_43135637 length=472nt
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIR
EVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMS
FITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSW
VCLLLYVWTLVAPLVLTSRDFS

>ZCCHC7_SERINC3_ENST00000336755_ENST00000255175_37126939_43135637 length=195nt
MPPFLLLEAVCVFLFSRVPPSLPLQEVHVSKETIGKISAASKMMWCSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSP
GTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSR

>ZCCHC7_SERINC3_ENST00000336755_ENST00000342374_37126939_43135637 length=472nt
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIR
EVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMS
FITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSW
VCLLLYVWTLVAPLVLTSRDFS

>ZCCHC7_SERINC3_ENST00000336755_ENST00000541235_37126939_43135637 length=472nt
MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIR
EVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDDDILLNLVGCENSVTEALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNEPDRSCNPNLMS
FITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSW
VCLLLYVWTLVAPLVLTSRDFS

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

Top

Personalized Fusion Protein Sequence for ZCCHC7_SERINC3

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

Top

Fusion Gene Exprssed Samples for ZCCHC7_SERINC3

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerKB3		Literature_Curation	Literature_Curation	ZCCHC7	chr9	37126939	+	SERINC3	chr20	43135637	-

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

Top

Related Drugs for ZCCHC7_SERINC3

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status