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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene Breakpoints

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness

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Fusion Genomic Features

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Fusion Gene ORF Annotations

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Fusion Protein Retained/Non-Retained Functional Features

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Fusion Transcript Sequences

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Fusion Protein Sequences

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Personalized Fusion Protein Sequences

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Fusion Gene Expressed Samples

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Related Drugs

Fusion gene:FBXL20_WIPF2 (FusionGDB2 ID:HG84961TG147179)

Fusion Gene Summary for FBXL20_WIPF2

check button Fusion gene summary
Fusion gene informationFusion gene name: FBXL20_WIPF2
Fusion gene ID: hg84961tg147179
HgeneTgene
Gene symbol

FBXL20

WIPF2

Gene ID

84961

147179

Gene nameF-box and leucine rich repeat protein 20WAS/WASL interacting protein family member 2
SynonymsFbl2|Fbl20WICH|WIRE
Cytomap

17q12

17q21.2

Type of geneprotein-codingprotein-coding
DescriptionF-box/LRR-repeat protein 20F-box protein FBL2WAS/WASL-interacting protein family member 2WASP-binding proteinWASP-interacting protein-related proteinWIP- and CR16-homologous proteinWIP-related protein
Modification date2024040320240305
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000264658, ENST00000394294, 
ENST00000583610, ENST00000577399, 
Fusion gene scores* DoF score* DoF score (Degree of Frequency) = # partners X # break points X # disease types
76 X 42 X 29=92568		* DoF score (Degree of Frequency) = # partners X # break points X # disease types
13 X 37 X 10=4810
# samples 12245
** MAII score** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(122/92568*10)=-6.24556049889967
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)
log2(45/4810*10)=-3.41803998744037
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FBXL20 [Title/Abstract] AND WIPF2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFBXL20(37557613)-WIPF2(38434436), # samples:1


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Fusion Gene Breakpoints for FBXL20_WIPF2


check button RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbp
FBXL20chr1737557613WIPF2chr1737557613
FBXL20chr1737557614WIPF2chr1738434437
FBXL20chr1739401361WIPF2chr1740278185


check button DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.
HgeneHchrHbpTgeneTchrTbpSV type


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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for FBXL20_WIPF2


check button To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.
* We have 10 tumorigenic mechanism categories of fusion genes as shown below.
Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand FusionsAberrant Chimeric Transcription Factor / Fusion Transcription Factor ActivityEpigenetic Reprogramming / Histone Modifier DysregulationChromatin Remodeling DysregulationCondensate-Driven Transcriptional Rewiring / LLPPromoter / Enhancer HijackingDominant-Negative AntagonismCell Cycle / Checkpoint Bypass / RNA Processing DysregulationSubcellular Mislocalization / Spatial DysregulationNuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.
Fusion Gene NameMechanism CategoryMechanism PubMedTumorigenic ScenariosTumorigenic Scenario PubMedTargeting PointsTargeting PubMedMechanism BackgroundMechanism Background PubMed

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

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Fusion Genomic Features for FBXL20_WIPF2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FBXL20chr1737557613-WIPF2chr1738434436+3.10e-051.00e+00


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).
genomic feature

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Fusion Gene ORF Annotations for FBXL20_WIPF2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000264658ENST00000323571FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000264658ENST00000394103FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000264658ENST00000494757FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000264658ENST00000536600FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000264658ENST00000583130FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000264658ENST00000585043FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000323571FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000394103FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000494757FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000536600FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000583130FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000394294ENST00000585043FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000323571FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000394103FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000494757FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000536600FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000583130FBXL20chr17

37557613

-WIPF2chr17

38434436

+
5CDS-3UTRENST00000583610ENST00000585043FBXL20chr17

37557613

-WIPF2chr17

38434436

+

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.
HenstTenstHgeneHchrHbpTgeneTchrTbpSeq length
(transcript)		Seq length
(peptide)

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score

check buttonDeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).
HenstTenstHgeneHchrHbpTgeneTchrTbpNo-coding scoreCoding score
ENST00000394294ENST00000536600FBXL20chr1737557613WIPF2chr17384344360.00e+009.45e-01
ENST00000583610ENST00000585043FBXL20chr1737557613WIPF2chr17384344360.00e+009.22e-01
ENST00000583610ENST00000583130FBXL20chr1737557613WIPF2chr17384344360.00e+007.41e-01
ENST00000583610ENST00000536600FBXL20chr1737557613WIPF2chr17384344360.00e+009.51e-01
ENST00000583610ENST00000494757FBXL20chr1737557613WIPF2chr17384344360.00e+007.12e-01
ENST00000583610ENST00000394103FBXL20chr1737557613WIPF2chr17384344360.00e+009.51e-01
ENST00000583610ENST00000323571FBXL20chr1737557613WIPF2chr17384344360.00e+009.88e-01
ENST00000394294ENST00000585043FBXL20chr1737557613WIPF2chr17384344360.00e+009.28e-01
ENST00000394294ENST00000583130FBXL20chr1737557613WIPF2chr17384344360.00e+007.02e-01
ENST00000264658ENST00000323571FBXL20chr1737557613WIPF2chr17384344360.00e+009.88e-01
ENST00000394294ENST00000494757FBXL20chr1737557613WIPF2chr17384344360.00e+007.81e-01
ENST00000394294ENST00000394103FBXL20chr1737557613WIPF2chr17384344360.00e+009.45e-01
ENST00000394294ENST00000323571FBXL20chr1737557613WIPF2chr17384344360.00e+009.87e-01
ENST00000264658ENST00000585043FBXL20chr1737557613WIPF2chr17384344360.00e+009.05e-01
ENST00000264658ENST00000583130FBXL20chr1737557613WIPF2chr17384344360.00e+007.31e-01
ENST00000264658ENST00000536600FBXL20chr1737557613WIPF2chr17384344360.00e+009.38e-01
ENST00000264658ENST00000494757FBXL20chr1737557613WIPF2chr17384344360.00e+006.91e-01
ENST00000264658ENST00000394103FBXL20chr1737557613WIPF2chr17384344360.00e+009.38e-01

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Fusion Protein Retained/Non-Retained Functional Features for FBXL20_WIPF2

check buttonProtein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.
fgviewer annotation
- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).
No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


check button - Retained PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerHgeneHbpTgeneTbpENSTUniProtStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Fusion Transcript Sequence for FBXL20_WIPF2

check button In-frame Fusion Transcript Sequences.

check button N-Truncated Transcript (5UTR-3CDS) Sequences

check button C-Truncated Transcript (5CDS-3UTR) Sequences
>FBXL20_WIPF2_ENST00000264658_ENST00000323571_37557613_38434436 length=6255nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCT
CCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACA
TGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTC
ATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGT
ATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTC
TCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTC
CTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGT
GCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCT
TGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGG
CAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCT
TTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGAC
AGAGCCAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAATTTAATCACACACATCACAGGCTTAAACTGTCTTAGAGACCTTTCCAGTTGATTGGATCACAGGCTAGGGATCTGTGCATGGTGCCAGGTGAAACCCAAGTCTCCCCAGT
GCTAGGTGAGGGAGGGCTCAACGGGGGTAATGTGTATGGGGTCTGCTGTCCTTTGCCATCCCCTGGACCATATTAACTCTGGGACAGACCATGATTAGGTCTGTCACCAAACTTTTCCTAATCATTTTTTATGTATCATTCTTCTTTCTA
ATCTGTTAGCAGTTATCTCCCAGAAGTATCCCTAGCATCCTGAAGCAAACAGAACTGCCGGGCGCTGTGGCTTATGCCTGTAATCTCAGCAATTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGAAGTTCGAGACCAGCCTGTCC
AACATGGTGAAACCCCGTCTCCACTAAAAACACAAAAATTATCTGGGCGTGGTGGCATGTGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAATCCAGGAGGTGGAGGTTGCAGTGAGTGGAGATGGCGCCACT
GCGCTCCAGCCCGGGTGACAGAGTGAAACTCCATCTCAGAAAACAAACAAACCAAACAACTGAGAGAGGGCATGCTAGTGGAGGGAAAAGGAGAGAGTACAAGAGTTGATACTGCATCAGAGTTCCAGGGCAGATACTGACAAGTGACTG
AACTTTGACTGTGAAGTCTTCCCATTTATTTTTGAAATGGGAGTCGATGCCTTTTGTACGTTATCAAAGTGTTTTTTTTTTTTTCCTCCTTTACTCAGACATAGAGCATCAAAATATCACGAGTAAAGCCAAACCCCAGCTTTTCACTGG
GGCTGATATCTTCCTCCCCATGGCCCACTGCCCCCTCATATTCCCCAGCACTTGGACTGTGTCACATGGGTATTGATTGTATACTTGTTGTCTTGGCCTCATGCAAAAAGGCCTGGGTCTAGATCTAGTCAGATGAGTTTTTTTTAGAGC
ATGTTGATGATACAACACCTGTTTAAATGTCTGCCTTATATGTTATTTGGTCCCACTGTTAATAATAGATTTATTACTATGTATATTTACTATTGAAGATGGGAATGTGATCTGCATAGTTATCAGTCTATTTTGTATGTTGTAAAAAGC
TTCTAATTTAGGTTTAAGGTGGGCTGGCTACAAGAGCACTAAAACTCCTCACCTTTTAAACTGCTCTTTTTATCTGCTTGTGGGAATGTCGTCTCTTTCGTGGAAGATTGGGTGGTCTCATGTTGAGGCTGTTGCCCAGTCCCATTAACT
CCCTTGTCCCCCCACAGAAGGAAGAGACATTGCCCAGCTAAGCATCAGGAAGCTGTGTTAAAAGCCCTTCTATGGGTTTGGTTTTGTGATGTTTTTCCCTAATGGGAAAAACGTTATAGTTGTTTCTTACTGCCCTGTCTGGGAAGCAGG
GCAAACCTCCAGGTTTTTAAATGAGCTAGATGCCCCTCTTCCTCTTCTCTGGTCACTGAACCTGGACCAAAGCACTTTGATATTCCAGGTGTGATTTTCTCTGTCATGGGGATTTGCTCCACTGCAGAGCCCCATCATTTTCACAGCGTA
GGCCAACAGAGTGAGAACCTAGGGCTACCCTAGCTGATGGATGTGAGGCTGCTGTCTACAGGAGCTCATCCCAGCCCTGTTAACTGGCAGTGGCAAGGATACTCGTCATCGGCCATTGCACTGGGGAACTCCCTCACCCCATGGCTTCCC
AACTTGAAACCCAGATTTACCTCCAGGGAGAGGTGAGAAAAAAATTGTAAATAGACTTGCTAAAGAGCAACTCAGGGTTGGGGTGTGTTTTAATTCTCCTGATCACTTGAAATAATCTGTAGGCTGAGTGCTTATGGGGGTGGGGGAGAA
GGGTGACTCCAGGGTCCTTCCATTTTGTGAAGCTCTGGGGGTGGAGTGTGGGCATCTGAGGCCCTATGATGGCACTACATTGAGCTGTCTGCCCTTCCGGAAACCCAACCTGCAATCAACTGCAAATCAAATTCTTCACATTCCAGCTAC
AGTCTTTCTTTCCCCATTGAATCTCAGTCCCTGGCCATGTGGTCAAGGTGGCTTTCTGTTAAGCTACCCTAATTTCGGGAATGGGAGGGGAGAGAGGAGGGCCATTACAACTCTGCCTTCAAGACTCATCTCTTAAAAACAAAACGAAAC
AAAACTACAACCACCATCAAAACCACACGCAAAAAAAAAAAAAAAAAAAAAAAGGATAACTTTAACCGAAGGAAGGGTTTGGTTCCATTCAACTCCACATTCATTGTGCCTTTACTTGCATTAGATTTCTGTGCTTTCTTCCTTTCCCTC
TTTGAAGCAATTAAAATCTTCCTTGATAACTGCTGTTTCTTTCTACTCTTGTTTCTGGCAATTTAGTGGGTTCCTTCTCTAGTGGTCTTAAATCTCATTCCACTGGTGGCAAGATGGGGCCTAGCCTTCTTTTCACATGTCTAATCTTTT
CCTTTCTCATGGTGCCCTCCATGGAAGTCACAGTCAACACTGAATAAATGACTAGAATGACACGTGTGCGTGCGCACGCGTGTGCGTGTGTGTGTTCATCTGTCTGCATGTGGATCAATTTCTTTTAGAAAATAATTTATTGTATGATTT
ATTTTGGAGTTATATTCTGATTACAGTGCTCCCTCTCCCAAATAGCATTGATTTTTTCCCCCCTCTAAAATGTATAATCTGGTCTCAGGTTGGATTCTTTGGTACATTTCTCTCTTCTGGATGCCATGCAGCTTAATTAAAACCTTGCTT
AAAAACAAAAAGTGAAAATTGTGTACTCTTGTCTGGAATACCGCCTCAGGTGGTGGCACAGAGAGGGGAGAAAACCTTTGCCTCATAATTTGGGTAAGTGTAGTGGTTTGATTCCAGGTCCCTTGAAAAAGTAGATCTACTGAATTGGGC
AGACTCATCTATAGCTTTCTGAGGGTCTTCTCTCCTCCTCTCCAGCTGTATTTTGAAAATTACAGTTCTAGTTGGCTGGGCGCGATGGCTCATGTCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCATTTGAGGTCAGGAG
TTCAAGACCAGCTTGGCCAACATGGTGAAACCCCGTCTCTACTGAAAATACAAAAATTAACCGGTGTCATGGCGCATGCCTGTAGTCCCAGCTACTCGGGAGGCCGAGGCAGGAAAATCACTTGAACCCAGGAGGCGGAGGTTGCACTGA
GCTGAGATCATGCCACTGCACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTCTAGAGTTCTAGTTACCCTTCCTGGGAGATTCTGATGGTCCTTATTTTATTATTATTATTATTTTTTTTTGAGACAGGATGTTGCTG
TCATCCAGGCTGGAGTGCAGTGGTGTGATCATAGCTCACCGCAGCCTCCAACTCTCAAGCTCAAGTGATCCTCCCACCTCAGCCTCCCGTGTAGCTGGGACCACAGGTGTGTACCACTATGCCTGGCTAATTTTGAAAATTTTTTTGTAA
AGACAGGGTCTCCCTATGTTGCCCAGACTGGTCTCAAATTCCTGGGCTTAAGTGATTGTCCCACCTCAGCTTCTCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCAGCCAGTCCTTATTTTATATTTCCACCTAACTCCCCTTT
GCCCACGATTTCAGGGAACCTAGGAGGCTTCCTGGCCTTGTGACCTTTTCCTTGAATCTCTTATAATTCTTTCTACCTGTGTTGCATGGCAGATTCTCAGATTGAGGCTAAAGAAAAGAAGGGTGGGGACAAAGCATACAGAATGTGTGT
ATCTGTTTTTATGTGGGTGTTGGCTGTTTTTCGTCACTGCTTTTTAAGCTGAATCTTAGCTGGTTTTCTTGAACTTTGACTTTAGGTGTAAAAATTCAACCAGACATTCTCTCCTTACTGTGGTCAGCTGACATCATAACCACTAAGGCT
TAATGAGCTTAACTTGCACTTTCATCACTAGCAAAGGTCTTGAAGTTATTTCTCTTACTGATTCATAATGGGTGTGTGTATGAATCACTCTCACATAATTTAGATATAAAAACCTATGAGGATGAGGGAGGGAGGGGAAGAAAAAAAAGG
ACTCCTTTCATTTTCATCCGTACTTCCCAGATGGGCTGAATCTCCGATTATTTGACCCATCATTGTTATTAATATGGTTAATAAACTACCTATTTATTGATTGAA

>FBXL20_WIPF2_ENST00000264658_ENST00000394103_37557613_38434436 length=1968nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCT
CCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACA
TGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTC
ATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGT
ATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTC
TCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTC
CTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGT
GCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCT
TGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGG
CAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCT
TTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGAC
AGAGCCAGACTCCGTCTC

>FBXL20_WIPF2_ENST00000264658_ENST00000494757_37557613_38434436 length=303nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAG

>FBXL20_WIPF2_ENST00000264658_ENST00000536600_37557613_38434436 length=1968nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCT
CCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACA
TGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTC
ATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGT
ATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTC
TCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTC
CTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGT
GCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCT
TGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGG
CAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCT
TTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGAC
AGAGCCAGACTCCGTCTC

>FBXL20_WIPF2_ENST00000264658_ENST00000583130_37557613_38434436 length=350nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTG

>FBXL20_WIPF2_ENST00000264658_ENST00000585043_37557613_38434436 length=1476nt
Breakpoint=303nt
GGGGAGTGTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGT
CACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTT
GAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCT
CCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACA
TGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTC
ATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGT
ATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTC
TCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTC
CTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGT
GCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCT

>FBXL20_WIPF2_ENST00000394294_ENST00000323571_37557613_38434436 length=6215nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAG
GTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGC
TCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGG
AAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGG
AGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACC
ACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGG
ACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGA
AGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCAT
GGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACA
GAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAA
AGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCA
GAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAA
TTTAATCACACACATCACAGGCTTAAACTGTCTTAGAGACCTTTCCAGTTGATTGGATCACAGGCTAGGGATCTGTGCATGGTGCCAGGTGAAACCCAAGTCTCCCCAGTGCTAGGTGAGGGAGGGCTCAACGGGGGTAATGTGTATGGG
GTCTGCTGTCCTTTGCCATCCCCTGGACCATATTAACTCTGGGACAGACCATGATTAGGTCTGTCACCAAACTTTTCCTAATCATTTTTTATGTATCATTCTTCTTTCTAATCTGTTAGCAGTTATCTCCCAGAAGTATCCCTAGCATCC
TGAAGCAAACAGAACTGCCGGGCGCTGTGGCTTATGCCTGTAATCTCAGCAATTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGAAGTTCGAGACCAGCCTGTCCAACATGGTGAAACCCCGTCTCCACTAAAAACACAAAAATT
ATCTGGGCGTGGTGGCATGTGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAATCCAGGAGGTGGAGGTTGCAGTGAGTGGAGATGGCGCCACTGCGCTCCAGCCCGGGTGACAGAGTGAAACTCCATCTCAGA
AAACAAACAAACCAAACAACTGAGAGAGGGCATGCTAGTGGAGGGAAAAGGAGAGAGTACAAGAGTTGATACTGCATCAGAGTTCCAGGGCAGATACTGACAAGTGACTGAACTTTGACTGTGAAGTCTTCCCATTTATTTTTGAAATGG
GAGTCGATGCCTTTTGTACGTTATCAAAGTGTTTTTTTTTTTTTCCTCCTTTACTCAGACATAGAGCATCAAAATATCACGAGTAAAGCCAAACCCCAGCTTTTCACTGGGGCTGATATCTTCCTCCCCATGGCCCACTGCCCCCTCATA
TTCCCCAGCACTTGGACTGTGTCACATGGGTATTGATTGTATACTTGTTGTCTTGGCCTCATGCAAAAAGGCCTGGGTCTAGATCTAGTCAGATGAGTTTTTTTTAGAGCATGTTGATGATACAACACCTGTTTAAATGTCTGCCTTATA
TGTTATTTGGTCCCACTGTTAATAATAGATTTATTACTATGTATATTTACTATTGAAGATGGGAATGTGATCTGCATAGTTATCAGTCTATTTTGTATGTTGTAAAAAGCTTCTAATTTAGGTTTAAGGTGGGCTGGCTACAAGAGCACT
AAAACTCCTCACCTTTTAAACTGCTCTTTTTATCTGCTTGTGGGAATGTCGTCTCTTTCGTGGAAGATTGGGTGGTCTCATGTTGAGGCTGTTGCCCAGTCCCATTAACTCCCTTGTCCCCCCACAGAAGGAAGAGACATTGCCCAGCTA
AGCATCAGGAAGCTGTGTTAAAAGCCCTTCTATGGGTTTGGTTTTGTGATGTTTTTCCCTAATGGGAAAAACGTTATAGTTGTTTCTTACTGCCCTGTCTGGGAAGCAGGGCAAACCTCCAGGTTTTTAAATGAGCTAGATGCCCCTCTT
CCTCTTCTCTGGTCACTGAACCTGGACCAAAGCACTTTGATATTCCAGGTGTGATTTTCTCTGTCATGGGGATTTGCTCCACTGCAGAGCCCCATCATTTTCACAGCGTAGGCCAACAGAGTGAGAACCTAGGGCTACCCTAGCTGATGG
ATGTGAGGCTGCTGTCTACAGGAGCTCATCCCAGCCCTGTTAACTGGCAGTGGCAAGGATACTCGTCATCGGCCATTGCACTGGGGAACTCCCTCACCCCATGGCTTCCCAACTTGAAACCCAGATTTACCTCCAGGGAGAGGTGAGAAA
AAAATTGTAAATAGACTTGCTAAAGAGCAACTCAGGGTTGGGGTGTGTTTTAATTCTCCTGATCACTTGAAATAATCTGTAGGCTGAGTGCTTATGGGGGTGGGGGAGAAGGGTGACTCCAGGGTCCTTCCATTTTGTGAAGCTCTGGGG
GTGGAGTGTGGGCATCTGAGGCCCTATGATGGCACTACATTGAGCTGTCTGCCCTTCCGGAAACCCAACCTGCAATCAACTGCAAATCAAATTCTTCACATTCCAGCTACAGTCTTTCTTTCCCCATTGAATCTCAGTCCCTGGCCATGT
GGTCAAGGTGGCTTTCTGTTAAGCTACCCTAATTTCGGGAATGGGAGGGGAGAGAGGAGGGCCATTACAACTCTGCCTTCAAGACTCATCTCTTAAAAACAAAACGAAACAAAACTACAACCACCATCAAAACCACACGCAAAAAAAAAA
AAAAAAAAAAAAAGGATAACTTTAACCGAAGGAAGGGTTTGGTTCCATTCAACTCCACATTCATTGTGCCTTTACTTGCATTAGATTTCTGTGCTTTCTTCCTTTCCCTCTTTGAAGCAATTAAAATCTTCCTTGATAACTGCTGTTTCT
TTCTACTCTTGTTTCTGGCAATTTAGTGGGTTCCTTCTCTAGTGGTCTTAAATCTCATTCCACTGGTGGCAAGATGGGGCCTAGCCTTCTTTTCACATGTCTAATCTTTTCCTTTCTCATGGTGCCCTCCATGGAAGTCACAGTCAACAC
TGAATAAATGACTAGAATGACACGTGTGCGTGCGCACGCGTGTGCGTGTGTGTGTTCATCTGTCTGCATGTGGATCAATTTCTTTTAGAAAATAATTTATTGTATGATTTATTTTGGAGTTATATTCTGATTACAGTGCTCCCTCTCCCA
AATAGCATTGATTTTTTCCCCCCTCTAAAATGTATAATCTGGTCTCAGGTTGGATTCTTTGGTACATTTCTCTCTTCTGGATGCCATGCAGCTTAATTAAAACCTTGCTTAAAAACAAAAAGTGAAAATTGTGTACTCTTGTCTGGAATA
CCGCCTCAGGTGGTGGCACAGAGAGGGGAGAAAACCTTTGCCTCATAATTTGGGTAAGTGTAGTGGTTTGATTCCAGGTCCCTTGAAAAAGTAGATCTACTGAATTGGGCAGACTCATCTATAGCTTTCTGAGGGTCTTCTCTCCTCCTC
TCCAGCTGTATTTTGAAAATTACAGTTCTAGTTGGCTGGGCGCGATGGCTCATGTCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCATTTGAGGTCAGGAGTTCAAGACCAGCTTGGCCAACATGGTGAAACCCCGTCTCT
ACTGAAAATACAAAAATTAACCGGTGTCATGGCGCATGCCTGTAGTCCCAGCTACTCGGGAGGCCGAGGCAGGAAAATCACTTGAACCCAGGAGGCGGAGGTTGCACTGAGCTGAGATCATGCCACTGCACTAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAATTCTAGAGTTCTAGTTACCCTTCCTGGGAGATTCTGATGGTCCTTATTTTATTATTATTATTATTTTTTTTTGAGACAGGATGTTGCTGTCATCCAGGCTGGAGTGCAGTGGTGTGATCATAGCTCACC
GCAGCCTCCAACTCTCAAGCTCAAGTGATCCTCCCACCTCAGCCTCCCGTGTAGCTGGGACCACAGGTGTGTACCACTATGCCTGGCTAATTTTGAAAATTTTTTTGTAAAGACAGGGTCTCCCTATGTTGCCCAGACTGGTCTCAAATT
CCTGGGCTTAAGTGATTGTCCCACCTCAGCTTCTCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCAGCCAGTCCTTATTTTATATTTCCACCTAACTCCCCTTTGCCCACGATTTCAGGGAACCTAGGAGGCTTCCTGGCCTTG
TGACCTTTTCCTTGAATCTCTTATAATTCTTTCTACCTGTGTTGCATGGCAGATTCTCAGATTGAGGCTAAAGAAAAGAAGGGTGGGGACAAAGCATACAGAATGTGTGTATCTGTTTTTATGTGGGTGTTGGCTGTTTTTCGTCACTGC
TTTTTAAGCTGAATCTTAGCTGGTTTTCTTGAACTTTGACTTTAGGTGTAAAAATTCAACCAGACATTCTCTCCTTACTGTGGTCAGCTGACATCATAACCACTAAGGCTTAATGAGCTTAACTTGCACTTTCATCACTAGCAAAGGTCT
TGAAGTTATTTCTCTTACTGATTCATAATGGGTGTGTGTATGAATCACTCTCACATAATTTAGATATAAAAACCTATGAGGATGAGGGAGGGAGGGGAAGAAAAAAAAGGACTCCTTTCATTTTCATCCGTACTTCCCAGATGGGCTGAA
TCTCCGATTATTTGACCCATCATTGTTATTAATATGGTTAATAAACTACCTATTTATTGATTGAA

>FBXL20_WIPF2_ENST00000394294_ENST00000394103_37557613_38434436 length=1928nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAG
GTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGC
TCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGG
AAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGG
AGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACC
ACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGG
ACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGA
AGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCAT
GGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACA
GAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAA
AGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCA
GAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCAGACTCCGTCTC

>FBXL20_WIPF2_ENST00000394294_ENST00000494757_37557613_38434436 length=263nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAG

>FBXL20_WIPF2_ENST00000394294_ENST00000536600_37557613_38434436 length=1928nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAG
GTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGC
TCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGG
AAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGG
AGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACC
ACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGG
ACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGA
AGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCAT
GGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTCCCAGGACTGCACGGTTTAACACAGCAGAGTACA
GAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAGCCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAA
AGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTTTCTACAACTGTTGCTATGTGTAGAGGGTGCTCA
GAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCAGACTCCGTCTC

>FBXL20_WIPF2_ENST00000394294_ENST00000583130_37557613_38434436 length=310nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAG
GTGAAGCCTG

>FBXL20_WIPF2_ENST00000394294_ENST00000585043_37557613_38434436 length=1436nt
Breakpoint=263nt
GAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCTCCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGG
CCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGCCCGTGGAGCCCCACCTCTGCCACCCATTCTCAG
GTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGCAATCAAGCCCTAGACTCCAAATGTCCTCCCAGC
TCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAACAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGG
AAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTTAGGAGGCTGGCATGACCAGGACTTATGGGTGGG
AGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGTTTTTGTTCTCACCTGCTGCCCCCCCACCCCACC
ACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAGCAAAGGGAACAGGAGCCATTTGAACCCTCTGGG
ACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTCACAAACCCCAAAAACCTCTGGTGGGAGATAGGA
AGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAGGATAACAAAGAAGGGCAGGTTGAAGCCCCTCAT
GGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCT

>FBXL20_WIPF2_ENST00000583610_ENST00000323571_37557613_38434436 length=6248nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGC
CCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGC
AATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAA
CAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTT
AGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGT
TTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAG
CAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTC
ACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAG
GATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTC
CCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAG
CCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTT
TCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCA
GACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAATTTAATCACACACATCACAGGCTTAAACTGTCTTAGAGACCTTTCCAGTTGATTGGATCACAGGCTAGGGATCTGTGCATGGTGCCAGGTGAAACCCAAGTCTCCCCAGTGCTAGGT
GAGGGAGGGCTCAACGGGGGTAATGTGTATGGGGTCTGCTGTCCTTTGCCATCCCCTGGACCATATTAACTCTGGGACAGACCATGATTAGGTCTGTCACCAAACTTTTCCTAATCATTTTTTATGTATCATTCTTCTTTCTAATCTGTT
AGCAGTTATCTCCCAGAAGTATCCCTAGCATCCTGAAGCAAACAGAACTGCCGGGCGCTGTGGCTTATGCCTGTAATCTCAGCAATTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGAAGTTCGAGACCAGCCTGTCCAACATGG
TGAAACCCCGTCTCCACTAAAAACACAAAAATTATCTGGGCGTGGTGGCATGTGCCTGTAGTCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATCGCTTGAATCCAGGAGGTGGAGGTTGCAGTGAGTGGAGATGGCGCCACTGCGCTCC
AGCCCGGGTGACAGAGTGAAACTCCATCTCAGAAAACAAACAAACCAAACAACTGAGAGAGGGCATGCTAGTGGAGGGAAAAGGAGAGAGTACAAGAGTTGATACTGCATCAGAGTTCCAGGGCAGATACTGACAAGTGACTGAACTTTG
ACTGTGAAGTCTTCCCATTTATTTTTGAAATGGGAGTCGATGCCTTTTGTACGTTATCAAAGTGTTTTTTTTTTTTTCCTCCTTTACTCAGACATAGAGCATCAAAATATCACGAGTAAAGCCAAACCCCAGCTTTTCACTGGGGCTGAT
ATCTTCCTCCCCATGGCCCACTGCCCCCTCATATTCCCCAGCACTTGGACTGTGTCACATGGGTATTGATTGTATACTTGTTGTCTTGGCCTCATGCAAAAAGGCCTGGGTCTAGATCTAGTCAGATGAGTTTTTTTTAGAGCATGTTGA
TGATACAACACCTGTTTAAATGTCTGCCTTATATGTTATTTGGTCCCACTGTTAATAATAGATTTATTACTATGTATATTTACTATTGAAGATGGGAATGTGATCTGCATAGTTATCAGTCTATTTTGTATGTTGTAAAAAGCTTCTAAT
TTAGGTTTAAGGTGGGCTGGCTACAAGAGCACTAAAACTCCTCACCTTTTAAACTGCTCTTTTTATCTGCTTGTGGGAATGTCGTCTCTTTCGTGGAAGATTGGGTGGTCTCATGTTGAGGCTGTTGCCCAGTCCCATTAACTCCCTTGT
CCCCCCACAGAAGGAAGAGACATTGCCCAGCTAAGCATCAGGAAGCTGTGTTAAAAGCCCTTCTATGGGTTTGGTTTTGTGATGTTTTTCCCTAATGGGAAAAACGTTATAGTTGTTTCTTACTGCCCTGTCTGGGAAGCAGGGCAAACC
TCCAGGTTTTTAAATGAGCTAGATGCCCCTCTTCCTCTTCTCTGGTCACTGAACCTGGACCAAAGCACTTTGATATTCCAGGTGTGATTTTCTCTGTCATGGGGATTTGCTCCACTGCAGAGCCCCATCATTTTCACAGCGTAGGCCAAC
AGAGTGAGAACCTAGGGCTACCCTAGCTGATGGATGTGAGGCTGCTGTCTACAGGAGCTCATCCCAGCCCTGTTAACTGGCAGTGGCAAGGATACTCGTCATCGGCCATTGCACTGGGGAACTCCCTCACCCCATGGCTTCCCAACTTGA
AACCCAGATTTACCTCCAGGGAGAGGTGAGAAAAAAATTGTAAATAGACTTGCTAAAGAGCAACTCAGGGTTGGGGTGTGTTTTAATTCTCCTGATCACTTGAAATAATCTGTAGGCTGAGTGCTTATGGGGGTGGGGGAGAAGGGTGAC
TCCAGGGTCCTTCCATTTTGTGAAGCTCTGGGGGTGGAGTGTGGGCATCTGAGGCCCTATGATGGCACTACATTGAGCTGTCTGCCCTTCCGGAAACCCAACCTGCAATCAACTGCAAATCAAATTCTTCACATTCCAGCTACAGTCTTT
CTTTCCCCATTGAATCTCAGTCCCTGGCCATGTGGTCAAGGTGGCTTTCTGTTAAGCTACCCTAATTTCGGGAATGGGAGGGGAGAGAGGAGGGCCATTACAACTCTGCCTTCAAGACTCATCTCTTAAAAACAAAACGAAACAAAACTA
CAACCACCATCAAAACCACACGCAAAAAAAAAAAAAAAAAAAAAAAGGATAACTTTAACCGAAGGAAGGGTTTGGTTCCATTCAACTCCACATTCATTGTGCCTTTACTTGCATTAGATTTCTGTGCTTTCTTCCTTTCCCTCTTTGAAG
CAATTAAAATCTTCCTTGATAACTGCTGTTTCTTTCTACTCTTGTTTCTGGCAATTTAGTGGGTTCCTTCTCTAGTGGTCTTAAATCTCATTCCACTGGTGGCAAGATGGGGCCTAGCCTTCTTTTCACATGTCTAATCTTTTCCTTTCT
CATGGTGCCCTCCATGGAAGTCACAGTCAACACTGAATAAATGACTAGAATGACACGTGTGCGTGCGCACGCGTGTGCGTGTGTGTGTTCATCTGTCTGCATGTGGATCAATTTCTTTTAGAAAATAATTTATTGTATGATTTATTTTGG
AGTTATATTCTGATTACAGTGCTCCCTCTCCCAAATAGCATTGATTTTTTCCCCCCTCTAAAATGTATAATCTGGTCTCAGGTTGGATTCTTTGGTACATTTCTCTCTTCTGGATGCCATGCAGCTTAATTAAAACCTTGCTTAAAAACA
AAAAGTGAAAATTGTGTACTCTTGTCTGGAATACCGCCTCAGGTGGTGGCACAGAGAGGGGAGAAAACCTTTGCCTCATAATTTGGGTAAGTGTAGTGGTTTGATTCCAGGTCCCTTGAAAAAGTAGATCTACTGAATTGGGCAGACTCA
TCTATAGCTTTCTGAGGGTCTTCTCTCCTCCTCTCCAGCTGTATTTTGAAAATTACAGTTCTAGTTGGCTGGGCGCGATGGCTCATGTCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCATTTGAGGTCAGGAGTTCAAGA
CCAGCTTGGCCAACATGGTGAAACCCCGTCTCTACTGAAAATACAAAAATTAACCGGTGTCATGGCGCATGCCTGTAGTCCCAGCTACTCGGGAGGCCGAGGCAGGAAAATCACTTGAACCCAGGAGGCGGAGGTTGCACTGAGCTGAGA
TCATGCCACTGCACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTCTAGAGTTCTAGTTACCCTTCCTGGGAGATTCTGATGGTCCTTATTTTATTATTATTATTATTTTTTTTTGAGACAGGATGTTGCTGTCATCCA
GGCTGGAGTGCAGTGGTGTGATCATAGCTCACCGCAGCCTCCAACTCTCAAGCTCAAGTGATCCTCCCACCTCAGCCTCCCGTGTAGCTGGGACCACAGGTGTGTACCACTATGCCTGGCTAATTTTGAAAATTTTTTTGTAAAGACAGG
GTCTCCCTATGTTGCCCAGACTGGTCTCAAATTCCTGGGCTTAAGTGATTGTCCCACCTCAGCTTCTCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCAGCCAGTCCTTATTTTATATTTCCACCTAACTCCCCTTTGCCCACG
ATTTCAGGGAACCTAGGAGGCTTCCTGGCCTTGTGACCTTTTCCTTGAATCTCTTATAATTCTTTCTACCTGTGTTGCATGGCAGATTCTCAGATTGAGGCTAAAGAAAAGAAGGGTGGGGACAAAGCATACAGAATGTGTGTATCTGTT
TTTATGTGGGTGTTGGCTGTTTTTCGTCACTGCTTTTTAAGCTGAATCTTAGCTGGTTTTCTTGAACTTTGACTTTAGGTGTAAAAATTCAACCAGACATTCTCTCCTTACTGTGGTCAGCTGACATCATAACCACTAAGGCTTAATGAG
CTTAACTTGCACTTTCATCACTAGCAAAGGTCTTGAAGTTATTTCTCTTACTGATTCATAATGGGTGTGTGTATGAATCACTCTCACATAATTTAGATATAAAAACCTATGAGGATGAGGGAGGGAGGGGAAGAAAAAAAAGGACTCCTT
TCATTTTCATCCGTACTTCCCAGATGGGCTGAATCTCCGATTATTTGACCCATCATTGTTATTAATATGGTTAATAAACTACCTATTTATTGATTGAA

>FBXL20_WIPF2_ENST00000583610_ENST00000394103_37557613_38434436 length=1961nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGC
CCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGC
AATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAA
CAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTT
AGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGT
TTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAG
CAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTC
ACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAG
GATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTC
CCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAG
CCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTT
TCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCA
GACTCCGTCTC

>FBXL20_WIPF2_ENST00000583610_ENST00000494757_37557613_38434436 length=296nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAG

>FBXL20_WIPF2_ENST00000583610_ENST00000536600_37557613_38434436 length=1961nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGC
CCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGC
AATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAA
CAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTT
AGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGT
TTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAG
CAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTC
ACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAG
GATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCTTCCTGTTCCTTTCTCTACCACCCTTGCCTTC
CCAGGACTGCACGGTTTAACACAGCAGAGTACAGAAGGGTGAAGAAGTGAGCAGAGGCTTATGAAGATATTCAGATACTCTTCTATGCCAGGAAGCACAAAGACTTTGTTGAGATTTGCCTCAGTTCAGTAGATCTTCCTTGGCAGCCAG
CCATAGGTTGTTTCTTTGTCTTCCGGGTCCTAAAGAGCACAGAGAAAATGGAGGTCCCCAGTCTAGGTAGGAAGCTGATTGGATGAGGACTTCTTTTTTTCCGACAGCAGGATGGGGCTCTTGGGCTCCACACACCAGATGCTTTGGTTT
TCTACAACTGTTGCTATGTGTAGAGGGTGCTCAGAGCGTGGCATGAGAGCAAGGAGACCATGGCTACTCTTTGAAATGGATGGGGAAAATTAGCTTAAAAATTTAATCACGAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCCA
GACTCCGTCTC

>FBXL20_WIPF2_ENST00000583610_ENST00000583130_37557613_38434436 length=343nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGC
CCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTG

>FBXL20_WIPF2_ENST00000583610_ENST00000585043_37557613_38434436 length=1469nt
Breakpoint=296nt
GTTTTTGTTTTGGGTTGAAGTTGAGGCTGAGGAGAGAGCCGAGCTAGCGACGAGCAGTCGTTGCGGCCGCCGGCGCCGCGGGAGGTGGTGGAGGCCTAGCCGGAGCCGAGAGGTCTCTTGTTCCCGTCCCACGGTCCCGGCGTCACCCCT
CCGGCGCCCAGTCCCCGTCCCGGAACTCCCGGGCCTGTCCTGGGCCCCCGGTCTGTGCACTCCGCTCGCCGCAGCGCCCGGCCCGGGCCGCACCCGCCGGCCCCATGAGGAGGGACGTGAACGGAGTGACCAAGAGCAGGTTTGAGCTGC
CCGTGGAGCCCCACCTCTGCCACCCATTCTCAGGTGAAGCCTGGCTTGGTCCCGTTCCTCAGGAAAAGGATGGACCTTCTCTTCTTCTCAGATGGTCCCTTCCATTCCCCTGAAACCTGCATGAGAGCTCCTAACATGTTTCTCCAATGC
AATCAAGCCCTAGACTCCAAATGTCCTCCCAGCTCACCTCCATCTATGCATCTCATCTCTGGATTTGGTGATCAGACTCTATATTGACAGTAGGATCTCAAACCCTGCATCCATCCTTCCTCCAGCAAGCCCTGCTAGCCACATGAGGAA
CAAGTTTCCGTGTCTTCTGCCTTCCTCTTGGGGAAAGGTGCCTTGTTGTGATGAATTAACTCACTGTTAGGGCAGGGTGGAGAATGGTACTCCTTCCTTCTCCTGTCCACTGTGGGGGAAGCTTGGCAGGTATATTATATTTCATCATTT
AGGAGGCTGGCATGACCAGGACTTATGGGTGGGAGGGGAGCATTTTTAGTGAAGCAAGAAAGGAGTTTGCCAAGAAGTGATCTGTTTTAAAGGTCATATTTGGAGAAAGGGCAAGGAATTGGGTCTGCTTTATTTTTGGGGGTATTTTGT
TTTTGTTCTCACCTGCTGCCCCCCCACCCCACCACCCCAGGGATAAATTGGATATAAACACTAAATACTAATCAGTTGAACTTAACATTTAATAAAAAGAAAGGGTGAAATAAACTGAAGACCATTTTAGAACTAGTCAGTTCTCTGCAG
CAAAGGGAACAGGAGCCATTTGAACCCTCTGGGACCCCTCACCCCACTGCTTCAGGGTGCTAGGCTGAGGGATGTTTTTCCTCCCCCTTACCGCCCATGCCCTTGAAAGAAAAGTCACTTTTTGTGGAGGGCATCATTCATTCCTGATTC
ACAAACCCCAAAAACCTCTGGTGGGAGATAGGAAGATAGGGCGTGGGCCTGGGCCTTAACCTCAATCTTGTGTCTGCCTCAGTCTTTTCTGACTGGCCCTGAAGTTGTCAGTGGCTCTTTCTGTCCTTCAGCCCCTGGAAGGTGCTCCAG
GATAACAAAGAAGGGCAGGTTGAAGCCCCTCATGGAAGGAGCTGGCTTTGTGGGGCTGCAAAGGACTTTTAAGTCCTGCCTGTACTGAAGTTCACAGCCCACCTGACTGAGCAGACTCT


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Fusion Protein Sequence for FBXL20_WIPF2

check button In-frame Fusion Protein Sequences.

check button N-Truncated Protein (5UTR-3CDS) Sequences

check button C-Truncated Protein (5CDS-3UTR) Sequences

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Personalized Fusion Protein Sequence for FBXL20_WIPF2


check button TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences
NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

NumGene GroupDomain LociFusion Protein IDFusion Gene NamePartnerMutated Residue in WT ProteinSeq. LengthMutated Residue in Fusion Protein

check button TCGA All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

check button CCLE All Mutated Fusion Protein Sequences


Fusion Protein IDSample IDMutated PartnerAAchange in WTSeq. LengthAAchange in Fusion

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Fusion Gene Exprssed Samples for FBXL20_WIPF2


check buttonRNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDBBRCATCGA-C8-A278-01AFBXL20

chr17

37557613-WIPF2

chr17

37557613

+
WashUBRCATCGA-C8-A278-01AFBXL20

chr17

37557614-WIPF2

chr17

38434437

+
cBioPortalBRCA_TCGA_PAN_CAN_ATLAS_2018BRCATCGA-C8-A278-01FBXL20

chr17

39401361WIPF2

chr17

40278185


check buttonDNA-seq based fusion gene expressed samples.
SourceStudyDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrandSV type


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Related Drugs for FBXL20_WIPF2


check button PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.
PMIDFusion Gene NameDrugStudy Title

check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status