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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:DPM1_CYP4F12 (FusionGDB2 ID:HG8813TG66002)

Fusion Gene Summary for DPM1_CYP4F12

Fusion gene summary

Fusion gene information	Fusion gene name: DPM1_CYP4F12
	Fusion gene ID: hg8813tg66002
		Hgene	Tgene
	Gene symbol	DPM1	CYP4F12
	Gene ID	8813	66002
	Gene name	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	cytochrome P450 family 4 subfamily F member 12
	Synonyms	CDGIE\|MPDS	CYPIVF12\|F22329_1
	Cytomap	20q13.13	19p13.12
	Type of gene	protein-coding	protein-coding
	Description	dolichol-phosphate mannosyltransferase subunit 1DPM synthase complex, catalytic subunitDPM synthase subunit 1MPD synthase subunit 1dolichol monophosphate mannose synthasedolichol-phosphate mannose synthase subunit 1dolichyl-phosphate beta-D-mannosyl	cytochrome P450 4F12cytochrome P450, family 4, subfamily F, polypeptide 12cytochrome P450, subfamily IVF, polypeptide 12
	Modification date	20240407	20240305
	UniProtAcc	O60762	.
	Ensembl transtripts involved in fusion gene	ENST00000466152, ENST00000371582, ENST00000371583, ENST00000371588,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 12 X 10 X 10=1200	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 4 X 7 X 4=112
	# samples	40	320
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(40/120010)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(320/11210)=4.83650126771712 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: DPM1 [Title/Abstract] AND CYP4F12 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	DPM1(49571722)-CYP4F12(15807239), # samples:1

Fusion gene breakpoints across DPM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CYP4F12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for DPM1_CYP4F12

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
DPM1	chr20	49571722	CYP4F12	chr19	15807240
DPM1	chr20	49571722	CYP4F12	chr19	49571722
DPM1	chr20	49571723	CYP4F12	chr19	15807240

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for DPM1_CYP4F12

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
DPM1-CYP4F12	Promoter / Enhancer Hijacking M6		Promoter swap alters cytochrome P450 4F12 expression, modifying eicosanoid and lipid metabolic clearance.		CYP4 family inhibitors; standard chemotherapy		Carcinomas

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
DPM1-CYP4F12	Promoter / Enhancer Hijacking M6		Promoter swap alters cytochrome P450 4F12 expression, modifying eicosanoid and lipid metabolic clearance.	Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 30280198; Title: Profiling cytochrome P450 family 4 gene expression in human hepatocellular carcinoma.; PMID: 32293332; Title: Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression.	CYP4 family inhibitors; standard chemotherapy		Carcinomas	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 30280198; Title: Profiling cytochrome P450 family 4 gene expression in human hepatocellular carcinoma.; PMID: 32293332; Title: Right and left-sided colon cancers - specificity of molecular mechanisms in tumorigenesis and progression.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
DPM1 O60762	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	DPM1	GO:0006506	GPI anchor biosynthetic process	9535917\|9724629
Hgene	DPM1	GO:0006506	GPI anchor biosynthetic process	9535917\|10835346
Hgene	DPM1	GO:0019348	dolichol metabolic process	9535917\|9724629
Hgene	DPM1	GO:0019348	dolichol metabolic process	10835346
Hgene	DPM1	GO:0035268	protein mannosylation	9535917
Hgene	DPM1	GO:0035269	protein O-linked mannosylation	9535917

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Fusion Genomic Features for DPM1_CYP4F12

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+	9.15e-04	9.99e-01

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+	9.15e-04	9.99e-01

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for DPM1_CYP4F12

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5UTR-3CDS	ENST00000466152	ENST00000324632	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
5UTR-3CDS	ENST00000466152	ENST00000550308	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371582	ENST00000324632	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371582	ENST00000550308	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371583	ENST00000324632	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371583	ENST00000550308	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371588	ENST00000324632	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+
In-frame	ENST00000371588	ENST00000550308	DPM1	chr20	49571722	-	CYP4F12	chr19	15807239	+

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000371582	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	293	173
ENST00000371582	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	293	173
ENST00000371583	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	270	173
ENST00000371583	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	270	173
ENST00000371588	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	288	173
ENST00000371588	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	288	111

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000466152	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	0	631
ENST00000466152	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	0	260

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000371582	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	7.15e-04	9.99e-01
ENST00000371582	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	1.25e-03	9.99e-01
ENST00000371583	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	7.15e-04	9.99e-01
ENST00000371583	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	1.29e-03	9.99e-01
ENST00000371588	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	8.06e-04	9.99e-01
ENST00000371588	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	1.45e-03	9.99e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000466152	ENST00000324632	DPM1	chr20	49571722	CYP4F12	chr19	15807239	0.00e+00	2.04e-01
ENST00000466152	ENST00000550308	DPM1	chr20	49571722	CYP4F12	chr19	15807239	0.00e+00	3.05e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for DPM1_CYP4F12

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

CYP4F12

chr20:49571722

chr19:15807239

ENST00000324632

Q9HCS2

19_39

438.0

525.0

Transmembrane

Helical

Tgene

CYP4F12

chr20:49571722

chr19:15807239

ENST00000324632

Q9HCS2

87_107

438.0

525.0

Transmembrane

Helical

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for DPM1_CYP4F12

In-frame Fusion Transcript Sequences.

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239 length=614nt 
 Breakpoint=293nt
ATTCCGCTTCCGGCATCTGGCTCAGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACC
TGCCGCTCATCGTGTGGCTGCTGGTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACG
ACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGT
TCCTGCCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAA
ACGGTGCTGTCACC

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239 length=643nt 
 Breakpoint=293nt
ATTCCGCTTCCGGCATCTGGCTCAGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACC
TGCCGCTCATCGTGTGGCTGCTGGTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACG
ACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGT
TCCTGCCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAA
ACGGTGCTGTCACCTCTGCCTGGGCCTCACTGACAGCCTGCAG

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239 length=591nt 
 Breakpoint=270nt
AGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACCTGCCGCTCATCGTGTGGCTGCTG
GTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACGACCCCTTCCGCTTTGACCCAGAG
AACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGTTCCTGCCAGACCACACTGAGCCC
CGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGTGCTGTCACC

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239 length=620nt 
 Breakpoint=270nt
AGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACCTGCCGCTCATCGTGTGGCTGCTG
GTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACGACCCCTTCCGCTTTGACCCAGAG
AACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGTTCCTGCCAGACCACACTGAGCCC
CGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGTGCTGTCACCTCTGCCTGG
GCCTCACTGACAGCCTGCAG

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239 length=609nt 
 Breakpoint=288nt
GCTTCCGGCATCTGGCTCAGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACCTGCCG
CTCATCGTGTGGCTGCTGGTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACGACCCC
TTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGTTCCTG
CCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGT
GCTGTCACC

>DPM1_CYP4F12_ENST00000371588_ENST00000550308_49571722_15807239 length=638nt 
 Breakpoint=288nt
GCTTCCGGCATCTGGCTCAGTTCCGCCATGGCCTCCTTGGAAGTCAGTCGTAGTCCTCGCAGGTCTCGGCGGGAGCTGGAAGTGCGCAGTCCACGACAGAACAAATATTCGGTGCTTTTACCTACCTACAACGAGCGCGAGAACCTGCCG
CTCATCGTGTGGCTGCTGGTGAAAAGCTTCTCCGAGAGTGGAATCAACTATGAAATTATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGATGTTGCTGAACAGTTGGAGAAGATCTATGGGTCAGACAGAATTGTCTACGACCCC
TTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCACTTCCGGTTCCTG
CCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGT
GCTGTCACCTCTGCCTGGGCCTCACTGACAGCCTGCAG

N-Truncated Transcript (5UTR-3CDS) Sequences

>DPM1_CYP4F12_ENST00000466152_ENST00000324632_49571722_15807239 length=321nt 
 Breakpoint=0nt
GTCTACGACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCAC
TTCCGGTTCCTGCCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCAT
GAATAAAACGGTGCTGTCACC

>DPM1_CYP4F12_ENST00000466152_ENST00000550308_49571722_15807239 length=350nt 
 Breakpoint=0nt
GTCTACGACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGCAGGGCCCAGGAACTGCATCGGGCAGGCGTTCGCCATGGCGGAGATGAAAGTGGTCCTGGCGTTGATGCTGCTGCAC
TTCCGGTTCCTGCCAGACCACACTGAGCCCCGCAGGAAGCTGGAATTGATCATGCGCGCCGAGGGCGGGCTTTGGCTGCGGGTGGAGCCCCTGAATGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCAT
GAATAAAACGGTGCTGTCACCTCTGCCTGGGCCTCACTGACAGCCTGCAG

C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for DPM1_CYP4F12

In-frame Fusion Protein Sequences.

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239 length=173nt
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239 length=173nt
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239 length=173nt
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239 length=173nt
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239 length=173nt
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000550308_49571722_15807239 length=111nt
MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMANFHLNDLEAPHEDDAEGEGEWD

N-Truncated Protein (5UTR-3CDS) Sequences

>DPM1_CYP4F12_ENST00000466152_ENST00000324632_49571722_15807239 length=631nt
MVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLI
KLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIR
PPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGITELHPDVVSYVSH
ATQQRLQNLVEKISETAQQKNFSYKDDDRYEQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALAAIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQR
ITRVNLRDLIFCLENERETSHSLLLYKAFLK

>DPM1_CYP4F12_ENST00000466152_ENST00000550308_49571722_15807239 length=260nt
MHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYELCRDLLCVLMPEPDAAACANHPLLQQDLVQLSLDWKTEIPDLVLPNGVQVSSKFQTTLVDMIYFLHGNMEVNVPSLAEVQLLLYTTVKVMGDSGHDQCQSLVLLNTHIALVKEDCV
FYPRIRSRNIPPPGAQFDVIKCHALSEFRCVVVPEKKNVSTVELVFLQKLKPSVGSRNSPPEHLQEAPNVQLFTTPLYLQGSQNVAPEVWKLTFNSQDEALWLISHLTRL

C-Truncated Protein (5CDS-3UTR) Sequences

Top

Personalized Fusion Protein Sequence for DPM1_CYP4F12

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.F443I_173_F92I length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPIRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.K479T_173_K128T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMTVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.G452V_173_G101V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKVRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.Q524K_173_Q173K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLK

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.A483V_173_A132V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLVLMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.S454P_173_S103P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRPPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.A508T_173_A157T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRTEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.F461L;p.I505M_173_F110L;I154M length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPLSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELMMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.L512F_173_L161F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGFWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R507C_173_R156C length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMCAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R507H_173_R156H length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMHAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.L514P_173_L163P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWPRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.L456V_173_L105V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPVAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.P455L_173_P104L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSLLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R500K_173_R149K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRKK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.P498L_173_P147L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTELRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.P437L_173_R86L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDLIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.R515Q_173_R164Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLQVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.E448Q_173_E97Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPQNSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.T496A_173_T145A length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHAEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.F443I_173_F92I length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPIRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.K479T_173_K128T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMTVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.G452V_173_G101V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKVRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.Q524K_173_Q173K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLK

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.A483V_173_A132V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLVLMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.S454P_173_S103P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRPPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.A508T_173_A157T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRTEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.F461L;p.I505M_173_F110L;I154M length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPLSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELMMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.L512F_173_L161F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGFWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R507C_173_R156C length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMCAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R507H_173_R156H length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMHAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.L514P_173_L163P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWPRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.L456V_173_L105V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPVAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.P455L_173_P104L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSLLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R500K_173_R149K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRKK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.P498L_173_P147L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTELRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.P437L_173_R86L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDLIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.R515Q_173_R164Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLQVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.E448Q_173_E97Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPQNSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.T496A_173_T145A length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHAEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371582_ENST00000550308_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.F443I_173_F92I length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPIRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.K479T_173_K128T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMTVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.G452V_173_G101V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKVRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.Q524K_173_Q173K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLK

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.A483V_173_A132V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLVLMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.S454P_173_S103P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRPPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.A508T_173_A157T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRTEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.F461L;p.I505M_173_F110L;I154M length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPLSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELMMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.L512F_173_L161F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGFWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R507C_173_R156C length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMCAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R507H_173_R156H length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMHAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.L514P_173_L163P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWPRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.L456V_173_L105V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPVAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.P455L_173_P104L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSLLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R500K_173_R149K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRKK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.P498L_173_P147L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTELRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.P437L_173_R86L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDLIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.R515Q_173_R164Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLQVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.E448Q_173_E97Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPQNSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.T496A_173_T145A length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHAEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.F443I_173_F92I length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPIRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.K479T_173_K128T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMTVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.G452V_173_G101V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKVRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.Q524K_173_Q173K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLK

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.A483V_173_A132V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLVLMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.S454P_173_S103P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRPPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.A508T_173_A157T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRTEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.F461L;p.I505M_173_F110L;I154M length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPLSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELMMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.L512F_173_L161F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGFWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R507C_173_R156C length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMCAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R507H_173_R156H length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMHAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.L514P_173_L163P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWPRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.L456V_173_L105V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPVAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.P455L_173_P104L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSLLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R500K_173_R149K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRKK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.P498L_173_P147L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTELRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.P437L_173_R86L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDLIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.R515Q_173_R164Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLQVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.E448Q_173_E97Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPQNSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.T496A_173_T145A length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHAEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371583_ENST00000550308_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.F443I_173_F92I length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPIRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.K479T_173_K128T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMTVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.G452V_173_G101V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKVRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.Q524K_173_Q173K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLK

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.A483V_173_A132V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLVLMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.S454P_173_S103P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRPPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.A508T_173_A157T length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRTEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.F461L;p.I505M_173_F110L;I154M length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPLSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELMMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.L512F_173_L161F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGFWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R507C_173_R156C length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMCAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R507H_173_R156H length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMHAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.L514P_173_L163P length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWPRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R515W_173_R164W length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLWVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.L456V_173_L105V length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPVAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.P460S_173_P109S length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFISFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.P455L_173_P104L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSLLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R500K_173_R149K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRKK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.D441N_173_D90N length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYNPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.P498L_173_P147L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTELRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.P437L_173_R86L length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDLIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.S462F_173_S111F length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFFAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.R515Q_173_R164Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLQVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.E448Q_173_E97Q length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPQNSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.T496A_173_T145A length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHAEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.E509K_173_E158K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAKGGLWLRVEPLNVSLQ

>DPM1_CYP4F12_ENST00000371588_ENST00000324632_49571722_15807239_3-gene_p.E477K_173_E126K length=173AA
MASLEVSRSPRRSRRELEVRSPRQNKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRIVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAKMKVVLALMLLHFRFLPDHTEPRRK
LELIMRAEGGLWLRVEPLNVSLQ

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-19-2629-01A	3-gene	p.R515W	173	R164W
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-24-2288-01A	3-gene	p.F443I	173	F92I
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-39-5036-01A	3-gene	p.K479T	173	K128T
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-50-5049-01A	3-gene	p.G452V	173	G101V
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-66-2767-01A	3-gene	p.Q524K	173	Q173K
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-A5-A0G2-01A	3-gene	p.D441N	173	D90N
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-A6-5660-01A	3-gene	p.A483V	173	A132V
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-AA-3672-01A	3-gene	p.S454P	173	S103P
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-AA-A01P-01A	3-gene	p.A508T	173	A157T
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-AN-A0AM-01A	3-gene	p.F461L;p.I505M	173	F110L;I154M
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-B5-A11E-01A	3-gene	p.L512F	173	L161F
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-BR-4184-01A	3-gene	p.R507C	173	R156C
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-CR-6482-01A	3-gene	p.R507H	173	R156H
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-D3-A8GC-06A	3-gene	p.S462F	173	S111F
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-D3-A8GM-06A	3-gene	p.P460S	173	P109S
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-D5-6533-01A	3-gene	p.L514P	173	L163P
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-DH-A66B-01A	3-gene	p.R515W	173	R164W
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-DK-A3IS-01A	3-gene	p.L456V	173	L105V
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EB-A44P-01A	3-gene	p.P460S	173	P109S
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EE-A182-06A	3-gene	p.P455L	173	P104L
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EE-A183-06A	3-gene	p.R500K	173	R149K
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EE-A2GC-06A	3-gene	p.D441N	173	D90N
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EE-A2GP-06A	3-gene	p.P498L	173	P147L
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EE-A3AC-06A	3-gene	p.P437L	173	R86L
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-ER-A193-06A	3-gene	p.S462F	173	S111F
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EY-A1GK-01A	3-gene	p.R515Q	173	R164Q
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-EY-A1GS-01A	3-gene	p.E509K	173	E158K
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-IH-A3EA-01A	3-gene	p.E477K	173	E126K
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-IR-A3LA-01A	3-gene	p.E448Q	173	E97Q
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-W3-A824-06A	3-gene	p.T496A	173	T145A
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-W3-AA1R-06A	3-gene	p.E509K	173	E158K
ENST00000371582_ENST00000324632_49571722_15807239	TCGA-YG-AA3O-06A	3-gene	p.E477K	173	E126K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-19-2629-01A	3-gene	p.R515W	173	R164W
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-24-2288-01A	3-gene	p.F443I	173	F92I
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-39-5036-01A	3-gene	p.K479T	173	K128T
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-50-5049-01A	3-gene	p.G452V	173	G101V
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-66-2767-01A	3-gene	p.Q524K	173	Q173K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-A5-A0G2-01A	3-gene	p.D441N	173	D90N
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-A6-5660-01A	3-gene	p.A483V	173	A132V
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-AA-3672-01A	3-gene	p.S454P	173	S103P
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-AA-A01P-01A	3-gene	p.A508T	173	A157T
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-AN-A0AM-01A	3-gene	p.F461L;p.I505M	173	F110L;I154M
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-B5-A11E-01A	3-gene	p.L512F	173	L161F
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-BR-4184-01A	3-gene	p.R507C	173	R156C
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-CR-6482-01A	3-gene	p.R507H	173	R156H
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-D3-A8GC-06A	3-gene	p.S462F	173	S111F
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-D3-A8GM-06A	3-gene	p.P460S	173	P109S
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-D5-6533-01A	3-gene	p.L514P	173	L163P
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-DH-A66B-01A	3-gene	p.R515W	173	R164W
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-DK-A3IS-01A	3-gene	p.L456V	173	L105V
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EB-A44P-01A	3-gene	p.P460S	173	P109S
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EE-A182-06A	3-gene	p.P455L	173	P104L
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EE-A183-06A	3-gene	p.R500K	173	R149K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EE-A2GC-06A	3-gene	p.D441N	173	D90N
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EE-A2GP-06A	3-gene	p.P498L	173	P147L
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EE-A3AC-06A	3-gene	p.P437L	173	R86L
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-ER-A193-06A	3-gene	p.S462F	173	S111F
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EY-A1GK-01A	3-gene	p.R515Q	173	R164Q
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-EY-A1GS-01A	3-gene	p.E509K	173	E158K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-IH-A3EA-01A	3-gene	p.E477K	173	E126K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-IR-A3LA-01A	3-gene	p.E448Q	173	E97Q
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-W3-A824-06A	3-gene	p.T496A	173	T145A
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-W3-AA1R-06A	3-gene	p.E509K	173	E158K
ENST00000371582_ENST00000550308_49571722_15807239	TCGA-YG-AA3O-06A	3-gene	p.E477K	173	E126K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-19-2629-01A	3-gene	p.R515W	173	R164W
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-24-2288-01A	3-gene	p.F443I	173	F92I
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-39-5036-01A	3-gene	p.K479T	173	K128T
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-50-5049-01A	3-gene	p.G452V	173	G101V
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-66-2767-01A	3-gene	p.Q524K	173	Q173K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-A5-A0G2-01A	3-gene	p.D441N	173	D90N
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-A6-5660-01A	3-gene	p.A483V	173	A132V
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-AA-3672-01A	3-gene	p.S454P	173	S103P
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-AA-A01P-01A	3-gene	p.A508T	173	A157T
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-AN-A0AM-01A	3-gene	p.F461L;p.I505M	173	F110L;I154M
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-B5-A11E-01A	3-gene	p.L512F	173	L161F
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-BR-4184-01A	3-gene	p.R507C	173	R156C
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-CR-6482-01A	3-gene	p.R507H	173	R156H
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-D3-A8GC-06A	3-gene	p.S462F	173	S111F
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-D3-A8GM-06A	3-gene	p.P460S	173	P109S
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-D5-6533-01A	3-gene	p.L514P	173	L163P
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-DH-A66B-01A	3-gene	p.R515W	173	R164W
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-DK-A3IS-01A	3-gene	p.L456V	173	L105V
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EB-A44P-01A	3-gene	p.P460S	173	P109S
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EE-A182-06A	3-gene	p.P455L	173	P104L
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EE-A183-06A	3-gene	p.R500K	173	R149K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EE-A2GC-06A	3-gene	p.D441N	173	D90N
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EE-A2GP-06A	3-gene	p.P498L	173	P147L
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EE-A3AC-06A	3-gene	p.P437L	173	R86L
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-ER-A193-06A	3-gene	p.S462F	173	S111F
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EY-A1GK-01A	3-gene	p.R515Q	173	R164Q
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-EY-A1GS-01A	3-gene	p.E509K	173	E158K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-IH-A3EA-01A	3-gene	p.E477K	173	E126K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-IR-A3LA-01A	3-gene	p.E448Q	173	E97Q
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-W3-A824-06A	3-gene	p.T496A	173	T145A
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-W3-AA1R-06A	3-gene	p.E509K	173	E158K
ENST00000371583_ENST00000324632_49571722_15807239	TCGA-YG-AA3O-06A	3-gene	p.E477K	173	E126K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-19-2629-01A	3-gene	p.R515W	173	R164W
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-24-2288-01A	3-gene	p.F443I	173	F92I
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-39-5036-01A	3-gene	p.K479T	173	K128T
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-50-5049-01A	3-gene	p.G452V	173	G101V
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-66-2767-01A	3-gene	p.Q524K	173	Q173K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-A5-A0G2-01A	3-gene	p.D441N	173	D90N
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-A6-5660-01A	3-gene	p.A483V	173	A132V
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-AA-3672-01A	3-gene	p.S454P	173	S103P
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-AA-A01P-01A	3-gene	p.A508T	173	A157T
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-AN-A0AM-01A	3-gene	p.F461L;p.I505M	173	F110L;I154M
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-B5-A11E-01A	3-gene	p.L512F	173	L161F
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-BR-4184-01A	3-gene	p.R507C	173	R156C
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-CR-6482-01A	3-gene	p.R507H	173	R156H
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-D3-A8GC-06A	3-gene	p.S462F	173	S111F
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-D3-A8GM-06A	3-gene	p.P460S	173	P109S
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-D5-6533-01A	3-gene	p.L514P	173	L163P
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-DH-A66B-01A	3-gene	p.R515W	173	R164W
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-DK-A3IS-01A	3-gene	p.L456V	173	L105V
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EB-A44P-01A	3-gene	p.P460S	173	P109S
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EE-A182-06A	3-gene	p.P455L	173	P104L
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EE-A183-06A	3-gene	p.R500K	173	R149K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EE-A2GC-06A	3-gene	p.D441N	173	D90N
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EE-A2GP-06A	3-gene	p.P498L	173	P147L
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EE-A3AC-06A	3-gene	p.P437L	173	R86L
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-ER-A193-06A	3-gene	p.S462F	173	S111F
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EY-A1GK-01A	3-gene	p.R515Q	173	R164Q
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-EY-A1GS-01A	3-gene	p.E509K	173	E158K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-IH-A3EA-01A	3-gene	p.E477K	173	E126K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-IR-A3LA-01A	3-gene	p.E448Q	173	E97Q
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-W3-A824-06A	3-gene	p.T496A	173	T145A
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-W3-AA1R-06A	3-gene	p.E509K	173	E158K
ENST00000371583_ENST00000550308_49571722_15807239	TCGA-YG-AA3O-06A	3-gene	p.E477K	173	E126K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-19-2629-01A	3-gene	p.R515W	173	R164W
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-24-2288-01A	3-gene	p.F443I	173	F92I
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-39-5036-01A	3-gene	p.K479T	173	K128T
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-50-5049-01A	3-gene	p.G452V	173	G101V
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-66-2767-01A	3-gene	p.Q524K	173	Q173K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-A5-A0G2-01A	3-gene	p.D441N	173	D90N
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-A6-5660-01A	3-gene	p.A483V	173	A132V
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-AA-3672-01A	3-gene	p.S454P	173	S103P
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-AA-A01P-01A	3-gene	p.A508T	173	A157T
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-AN-A0AM-01A	3-gene	p.F461L;p.I505M	173	F110L;I154M
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-B5-A11E-01A	3-gene	p.L512F	173	L161F
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-BR-4184-01A	3-gene	p.R507C	173	R156C
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-CR-6482-01A	3-gene	p.R507H	173	R156H
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-D3-A8GC-06A	3-gene	p.S462F	173	S111F
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-D3-A8GM-06A	3-gene	p.P460S	173	P109S
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-D5-6533-01A	3-gene	p.L514P	173	L163P
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-DH-A66B-01A	3-gene	p.R515W	173	R164W
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-DK-A3IS-01A	3-gene	p.L456V	173	L105V
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EB-A44P-01A	3-gene	p.P460S	173	P109S
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EE-A182-06A	3-gene	p.P455L	173	P104L
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EE-A183-06A	3-gene	p.R500K	173	R149K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EE-A2GC-06A	3-gene	p.D441N	173	D90N
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EE-A2GP-06A	3-gene	p.P498L	173	P147L
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EE-A3AC-06A	3-gene	p.P437L	173	R86L
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-ER-A193-06A	3-gene	p.S462F	173	S111F
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EY-A1GK-01A	3-gene	p.R515Q	173	R164Q
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-EY-A1GS-01A	3-gene	p.E509K	173	E158K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-IH-A3EA-01A	3-gene	p.E477K	173	E126K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-IR-A3LA-01A	3-gene	p.E448Q	173	E97Q
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-W3-A824-06A	3-gene	p.T496A	173	T145A
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-W3-AA1R-06A	3-gene	p.E509K	173	E158K
ENST00000371588_ENST00000324632_49571722_15807239	TCGA-YG-AA3O-06A	3-gene	p.E477K	173	E126K

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for DPM1_CYP4F12

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		OV	TCGA-13-0923-01A	DPM1	chr20	49571722	-	CYP4F12	chr19	15807240	+
ChimerDB		OV	TCGA-13-0923-01A	DPM1	chr20	49571722	-	CYP4F12	chr19	49571722	+
TCGAfusionPortal		OV	TCGA-13-0923-01A	DPM1	chr20	49571722	-	CYP4F12	chr19	15807240	+
WashU		OV	TCGA-13-0923-01A	DPM1	chr20	49571723	-	CYP4F12	chr19	15807240	+

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for DPM1_CYP4F12

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status