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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:OSBPL2-HM13 (FusionGDB2 ID:HG9885TG81502)

Fusion Gene Summary for OSBPL2-HM13

Fusion gene summary

Fusion gene information	Fusion gene name: OSBPL2-HM13
	Fusion gene ID: hg9885tg81502
		Hgene	Tgene
	Gene symbol	OSBPL2	HM13
	Gene ID	9885	81502
	Gene name	oxysterol binding protein like 2	histocompatibility minor 13
	Synonyms	DFNA67\|DNFA67\|ORP-2\|ORP2	H13\|IMP1\|IMPAS\|IMPAS-1\|MSTP086\|PSENL3\|PSL3\|SPP\|SPPL1
	Cytomap	('OSBPL2')('HM13') 20q13.33	20q11.21
	Type of gene	protein-coding	protein-coding
	Description	oxysterol-binding protein-related protein 2OSBP-related protein 2	minor histocompatibility antigen H13intramembrane protease 1minor histocompatibility antigen 13presenilin-like protein 3signal peptide peptidase betasignal peptide peptidase like 1
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000313733, ENST00000358053, ENST00000439951, ENST00000471817,
Fusion gene scores	* DoF score	16 X 11 X 9=1584	16 X 19 X 12=3648
	# samples	19	25
	** MAII score	log2(19/1584*10)=-3.05950101174866 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(25/3648*10)=-3.86710572950266 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: OSBPL2 [Title/Abstract] AND HM13 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	OSBPL2(60848462)-HM13(30102284), # samples:2
Anticipated loss of major functional domain due to fusion event.	OSBPL2-HM13 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. OSBPL2-HM13 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. OSBPL2-HM13 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. OSBPL2-HM13 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	OSBPL2	GO:0051289	protein homotetramerization	30581148
Tgene	HM13	GO:0033619	membrane protein proteolysis	14741365

Fusion gene breakpoints across OSBPL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HM13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-38-4630-01A	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
ChimerDB4	LUAD	TCGA-38-4630-01A	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+

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Fusion Gene ORF analysis for OSBPL2-HM13

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000313733	ENST00000335574	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000313733	ENST00000340852	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000313733	ENST00000376127	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000313733	ENST00000398174	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000358053	ENST00000335574	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000358053	ENST00000340852	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000358053	ENST00000376127	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000358053	ENST00000398174	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000439951	ENST00000335574	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000439951	ENST00000340852	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000439951	ENST00000376127	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-5UTR	ENST00000439951	ENST00000398174	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-intron	ENST00000313733	ENST00000492709	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
5CDS-intron	ENST00000313733	ENST00000492709	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-intron	ENST00000358053	ENST00000492709	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
5CDS-intron	ENST00000358053	ENST00000492709	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
5CDS-intron	ENST00000439951	ENST00000492709	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
5CDS-intron	ENST00000439951	ENST00000492709	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
In-frame	ENST00000313733	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000313733	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000313733	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000313733	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000358053	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000358053	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000358053	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000358053	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000439951	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000439951	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000439951	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
In-frame	ENST00000439951	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-3CDS	ENST00000471817	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-3CDS	ENST00000471817	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-3CDS	ENST00000471817	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-3CDS	ENST00000471817	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-5UTR	ENST00000471817	ENST00000335574	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
intron-5UTR	ENST00000471817	ENST00000340852	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
intron-5UTR	ENST00000471817	ENST00000376127	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
intron-5UTR	ENST00000471817	ENST00000398174	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+
intron-intron	ENST00000471817	ENST00000492709	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+
intron-intron	ENST00000471817	ENST00000492709	OSBPL2	chr20	60848462	+	HM13	chr20	30102284	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000439951	OSBPL2	chr20	60847315	+	ENST00000398174	HM13	chr20	30115287	+	1986	540	408	1637	409
ENST00000439951	OSBPL2	chr20	60847315	+	ENST00000340852	HM13	chr20	30115287	+	1839	540	408	1490	360
ENST00000439951	OSBPL2	chr20	60847315	+	ENST00000335574	HM13	chr20	30115287	+	2042	540	408	1541	377
ENST00000439951	OSBPL2	chr20	60847315	+	ENST00000376127	HM13	chr20	30115287	+	1688	540	408	1364	318
ENST00000313733	OSBPL2	chr20	60847315	+	ENST00000398174	HM13	chr20	30115287	+	2041	595	202	1692	496
ENST00000313733	OSBPL2	chr20	60847315	+	ENST00000340852	HM13	chr20	30115287	+	1894	595	202	1545	447
ENST00000313733	OSBPL2	chr20	60847315	+	ENST00000335574	HM13	chr20	30115287	+	2097	595	202	1596	464
ENST00000313733	OSBPL2	chr20	60847315	+	ENST00000376127	HM13	chr20	30115287	+	1743	595	202	1419	405
ENST00000358053	OSBPL2	chr20	60847315	+	ENST00000398174	HM13	chr20	30115287	+	2005	559	202	1656	484
ENST00000358053	OSBPL2	chr20	60847315	+	ENST00000340852	HM13	chr20	30115287	+	1858	559	202	1509	435
ENST00000358053	OSBPL2	chr20	60847315	+	ENST00000335574	HM13	chr20	30115287	+	2061	559	202	1560	452
ENST00000358053	OSBPL2	chr20	60847315	+	ENST00000376127	HM13	chr20	30115287	+	1707	559	202	1383	393

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000439951	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.011742459	0.9882576
ENST00000439951	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.0072573	0.99274266
ENST00000439951	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.016928423	0.9830716
ENST00000439951	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.008045426	0.9919546
ENST00000313733	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.011670576	0.9883294
ENST00000313733	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.007852771	0.99214727
ENST00000313733	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.01435722	0.98564285
ENST00000313733	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.00580599	0.994194
ENST00000358053	ENST00000398174	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.00608196	0.99391806
ENST00000358053	ENST00000340852	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.004163268	0.99583673
ENST00000358053	ENST00000335574	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.007249753	0.9927503
ENST00000358053	ENST00000376127	OSBPL2	chr20	60847315	+	HM13	chr20	30115287	+	0.003353941	0.996646

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Fusion Genomic Features for OSBPL2-HM13

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
OSBPL2	chr20	60847315	+	HM13	chr20	30115286	+	8.71E-12	1
OSBPL2	chr20	60847315	+	HM13	chr20	30115286	+	8.71E-12	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for OSBPL2-HM13

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:60848462/chr20:30102284)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

317_319

442.0

Motif

Note=PAL

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

317_319

378.0

Motif

Note=PAL

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

317_319

336.0

Motif

Note=PAL

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

317_319

427.0

Motif

Note=PAL

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

122_157

442.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

179_181

442.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

203_209

442.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

231_256

442.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

278_290

442.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

312_314

442.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

336_377

442.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

99_100

442.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

122_157

378.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

179_181

378.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

203_209

378.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

231_256

378.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

278_290

378.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

312_314

378.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

336_377

378.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

99_100

378.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

122_157

336.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

179_181

336.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

203_209

336.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

231_256

336.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

278_290

336.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

312_314

336.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

336_377

336.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

99_100

336.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

122_157

427.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

179_181

427.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

203_209

427.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

231_256

427.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

278_290

427.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

312_314

427.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

336_377

427.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

99_100

427.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

101_121

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

158_178

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

182_202

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

210_230

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

257_277

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

291_311

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

315_335

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

78_98

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

101_121

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

158_178

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

182_202

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

210_230

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

257_277

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

291_311

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

315_335

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

78_98

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

101_121

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

158_178

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

182_202

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

210_230

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

257_277

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

291_311

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

315_335

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

78_98

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

101_121

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

158_178

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

182_202

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

210_230

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

257_277

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

291_311

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

315_335

427.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

78_98

427.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

OSBPL2

chr20:60847315

chr20:30115287

ENST00000313733

427_431

131

481.0

Region

Phosphatidylinositol-4%2C5-bisphosphate binding

Hgene

OSBPL2

chr20:60847315

chr20:30115287

ENST00000358053

427_431

119

469.0

Region

Phosphatidylinositol-4%2C5-bisphosphate binding

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

1_31

442.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

53_77

442.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

1_31

378.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

53_77

378.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

1_31

336.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

53_77

336.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

1_31

427.0

Topological domain

Lumenal

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

53_77

427.0

Topological domain

Cytoplasmic

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000335574

32_52

442.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000340852

32_52

378.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000376127

32_52

336.0

Transmembrane

Helical

Tgene

HM13

chr20:60847315

chr20:30115287

ENST00000398174

32_52

427.0

Transmembrane

Helical

Top

Fusion Gene Sequence for OSBPL2-HM13

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>61806_61806_1_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000335574_length(transcript)=2097nt_BP=595nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGCTTTGATTCTGATAACTCTTCTGGGGAATT
TTCAGAGGCAAATCAGAAAGTCACGGGAATGATTGACTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCA
AGAGAACGGAATTCAGAAACACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTG
TGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCA
CGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCG
GGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCT
CCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTT
TCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCT
GGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTC
CCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGT
ATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCT
CGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTT
GAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAA
GCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGAT
GTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCATACCCCGAGGCTCACCCACTTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGC
CGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCGCCGGCGCCCGCAGAATCCCAGCGCCATGTAATGCCCAGCGGGTGCCCACCTGCC
CGCTTCCCCCTACTGCCCCGGGGCCCAAGTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAG
GCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGG
GCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGC
CTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCC
TCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGATTTTGCCTCACATTAAAAACTCATCCCATGG

>61806_61806_1_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000335574_length(amino acids)=464AA_BP=131
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSK
ITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFF
VLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELL
HLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTY
FYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKL

--------------------------------------------------------------
>61806_61806_2_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000340852_length(transcript)=1894nt_BP=595nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGCTTTGATTCTGATAACTCTTCTGGGGAATT
TTCAGAGGCAAATCAGAAAGTCACGGGAATGATTGACTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCA
AGAGAACGGAATTCAGAAACACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTG
TGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCA
CGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCG
GGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCT
CCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTT
TCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCT
GGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTC
CCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGT
ATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCT
CGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTT
GAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAA
GCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGAT
GTTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGA
GAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTA
GAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCT
CCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAA
GTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGATTTTGCCTCACATTAAAAACTCATCCCATGGCCAGGGCGGGCCACTGTGCTCCT

>61806_61806_2_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000340852_length(amino acids)=447AA_BP=131
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSK
ITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFF
VLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELL
HLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTY

--------------------------------------------------------------
>61806_61806_3_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000376127_length(transcript)=1743nt_BP=595nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGCTTTGATTCTGATAACTCTTCTGGGGAATT
TTCAGAGGCAAATCAGAAAGTCACGGGAATGATTGACTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCA
AGAGAACGGAATTCAGAAACACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTG
TGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCA
CGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCG
GGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCT
CCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTT
TCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCT
GGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTC
CTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGA
TGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTT
TGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGC
CTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGC
GGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCT
CTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGG
GCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCC
TGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGA

>61806_61806_3_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000376127_length(amino acids)=405AA_BP=131
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSK
ITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFF
VLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKVFGTNVMVTVAKSFEAPIKL
VFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVL

--------------------------------------------------------------
>61806_61806_4_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000398174_length(transcript)=2041nt_BP=595nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGCTTTGATTCTGATAACTCTTCTGGGGAATT
TTCAGAGGCAAATCAGAAAGTCACGGGAATGATTGACTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCA
AGAGAACGGAATTCAGAAACACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTG
TGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCA
CGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCG
GGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCT
CCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTT
TCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCT
GGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTC
CCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGT
ATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCT
CGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTT
GAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAA
GCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGAT
GTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCATACCCCGAGGCTCACCCACTTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGC
CGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCGCCGGCGCCCGCAGAATCCCAGCGCCATTTATGAGGAGTCAAATCCTAAGGATCC
AGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAG
CCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGAC
AGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACA
CCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGAC

>61806_61806_4_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000313733_HM13_chr20_30115287_ENST00000398174_length(amino acids)=496AA_BP=131
MNGEEEFFDAVTGFDSDNSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSK
ITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFF
VLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELL
HLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTY
FYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKL

--------------------------------------------------------------
>61806_61806_5_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000335574_length(transcript)=2061nt_BP=559nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGAGGCAAATCAGAAAGTCACGGGAATGATTGA
CTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCAAGAGAACGGAATTCAGAAACACAGGACATCGCTGCC
GGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAAT
CGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCA
GCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCAC
ACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCT
GGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGG
TTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTG
GTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGT
CAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTC
CTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGA
TGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTT
TGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGC
CTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCA
TACCCCGAGGCTCACCCACTTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGCCGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCG
CCGGCGCCCGCAGAATCCCAGCGCCATGTAATGCCCAGCGGGTGCCCACCTGCCCGCTTCCCCCTACTGCCCCGGGGCCCAAGTTATGAG
GAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAA
TGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAG
GCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCC
CTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTT

>61806_61806_5_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000335574_length(amino acids)=452AA_BP=119
MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLS
FLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTIS
PFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILL
GGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGL
GLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPS

--------------------------------------------------------------
>61806_61806_6_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000340852_length(transcript)=1858nt_BP=559nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGAGGCAAATCAGAAAGTCACGGGAATGATTGA
CTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCAAGAGAACGGAATTCAGAAACACAGGACATCGCTGCC
GGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAAT
CGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCA
GCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCAC
ACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCT
GGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGG
TTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTG
GTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGT
CAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTC
CTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGA
TGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTT
TGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGC
CTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGC
GGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCT
CTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGG
GCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCC
TGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGA

>61806_61806_6_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000340852_length(amino acids)=435AA_BP=119
MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLS
FLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTIS
PFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILL
GGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGL

--------------------------------------------------------------
>61806_61806_7_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000376127_length(transcript)=1707nt_BP=559nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGAGGCAAATCAGAAAGTCACGGGAATGATTGA
CTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCAAGAGAACGGAATTCAGAAACACAGGACATCGCTGCC
GGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAAT
CGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCA
GCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCAC
ACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCT
GGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGG
TTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTG
GTACCTGCTGAGGAAGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGA
TCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCT
GCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTT
CATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAA
GGGAGAAGTGACAGAGATGTTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATC
AGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCA
CACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTG
TGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCC

>61806_61806_7_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000376127_length(amino acids)=393AA_BP=119
MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLS
FLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTIS
PFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLE
ANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMF

--------------------------------------------------------------
>61806_61806_8_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000398174_length(transcript)=2005nt_BP=559nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGAGGCAAATCAGAAAGTCACGGGAATGATTGA
CTTAGACACCAGCAAAAATAATAGGATTGGGAAAACTGGGGAGAGGCCCTCTCAAGAGAACGGAATTCAGAAACACAGGACATCGCTGCC
GGCTCCCATGTTCAGCAGAAGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGGAGCTGTCCAAGATCACGATGCCAAT
CGCCTTCAACGAGCCTCTGAGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCA
GCCCCTGGAGAGGATGCAGAATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCAC
ACTCTTGGGGCTCTACCTCTTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCT
GGCCCTGTCCCACACCATCAGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGG
TTCTGGGGAAAACAAGGAAGAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTG
GTACCTGCTGAGGAAGCACTGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGT
CAGCACTGGCTGCATCCTGCTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTC
CTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGA
TGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTT
TGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGC
CTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCA
TACCCCGAGGCTCACCCACTTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGCCGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCG
CCGGCGCCCGCAGAATCCCAGCGCCATTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGC
ATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGC
CCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCT
CTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTC
CCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGATTTTGCCTCACATTAAAAACTCATCCCATGGCC

>61806_61806_8_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000358053_HM13_chr20_30115287_ENST00000398174_length(amino acids)=484AA_BP=119
MNGEEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQKHRTSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLS
FLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTIS
PFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILL
GGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGL
GLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPS

--------------------------------------------------------------
>61806_61806_9_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000335574_length(transcript)=2042nt_BP=540nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGA
AGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGACTTACGGAAAATCACAAAATAGCACAGAGCATTCCTGTAGACCC
ACCACCCAGCTCCCCTGATGCCGGCATCTCTCGGAATAACCATAGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTG
AGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAG
AATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTC
TTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATC
AGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAA
GAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCAC
TGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTG
CTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAA
TTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATC
TTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGC
CTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTC
CTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCATACCCCGAGGCTCACCCAC
TTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGCCGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCGCCGGCGCCCGCAGAATCCC
AGCGCCATGTAATGCCCAGCGGGTGCCCACCTGCCCGCTTCCCCCTACTGCCCCGGGGCCCAAGTTATGAGGAGTCAAATCCTAAGGATC
CAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGA
GCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGA
CAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCAC
ACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGA

>61806_61806_9_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000335574_length(amino acids)=377AA_BP=44
MSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSM
YFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGV
ELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNT
HTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQ

--------------------------------------------------------------
>61806_61806_10_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000340852_length(transcript)=1839nt_BP=540nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGA
AGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGACTTACGGAAAATCACAAAATAGCACAGAGCATTCCTGTAGACCC
ACCACCCAGCTCCCCTGATGCCGGCATCTCTCGGAATAACCATAGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTG
AGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAG
AATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTC
TTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATC
AGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAA
GAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCAC
TGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTG
CTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAA
TTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATC
TTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGC
CTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTC
CTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAA
GAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACA
GATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATAC
CTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCC
CAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGATTTTGCCTCACATTAAAAA

>61806_61806_10_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000340852_length(amino acids)=360AA_BP=44
MSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSM
YFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGV
ELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNT
HTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTESKEGTEASASKGLEKKEK

--------------------------------------------------------------
>61806_61806_11_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000376127_length(transcript)=1688nt_BP=540nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGA
AGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGACTTACGGAAAATCACAAAATAGCACAGAGCATTCCTGTAGACCC
ACCACCCAGCTCCCCTGATGCCGGCATCTCTCGGAATAACCATAGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTG
AGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAG
AATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTC
TTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATC
AGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAA
GAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGGTA
TTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAATTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTC
GAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATCTTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTG
AAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGCCTGGGCCTTACCATCTTCATCATGCACATCTTCAAG
CATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTCCTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATG
TTCAGTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTGGAG
AAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGGTAG
AGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTTCTC
CCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAAAAG

>61806_61806_11_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000376127_length(amino acids)=318AA_BP=44
MSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSM
YFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKVFGTNVMVTVAKSFEAP
IKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGF

--------------------------------------------------------------
>61806_61806_12_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000398174_length(transcript)=1986nt_BP=540nt
AGTGGGTCGCGGGCCTACGGGGCGGGGGCGGGGCGGCAGTGAGCTCGGCCGGCAACCGAGGGACCCGCGTCCAGATCTTCAGTGTCTATT
GGATTTTTCCAAGAGAAAGTTTGTAAAATTCCTTACACTGTAGATGTGGATCAGATACGATGATTCAGTAGAAGAGCACATGTCAGGGGC
AGTGGAGGCTGGCTGCTGAAGGATGAACGGAGAGGAAGAATTCTTTGATGCCGTCACAGGACATCGCTGCCGGCTCCCATGTTCAGCAGA
AGCGACTTCAGCGTGTGGACCATCCTGAAGAAGTGTGTTGGCCTGACTTACGGAAAATCACAAAATAGCACAGAGCATTCCTGTAGACCC
ACCACCCAGCTCCCCTGATGCCGGCATCTCTCGGAATAACCATAGGAGCTGTCCAAGATCACGATGCCAATCGCCTTCAACGAGCCTCTG
AGCTTCTTGCAGCGGATCACGGAGTACATGGAGCACGTGTACCTCATCCACAGGGCCTCCTGCCAGCCCCAGCCCCTGGAGAGGATGCAG
AATGCTTCAGACATGCCTGAAACAATCACCAGCCGGGATGCCGCCCGCTTCCCCATCATCGCCAGCTGCACACTCTTGGGGCTCTACCTC
TTTTTCAAAATATTCTCCCAGGAGTACATCAACCTCCTGCTGTCCATGTATTTCTTCGTGCTGGGAATCCTGGCCCTGTCCCACACCATC
AGCCCCTTCATGAATAAGTTTTTTCCAGCCAGCTTTCCAAATCGACAGTACCAGCTGCTCTTCACACAGGGTTCTGGGGAAAACAAGGAA
GAGATCATCAATTATGAATTTGACACCAAGGACCTGGTGTGCCTGGGCCTGAGCAGCATCGTTGGCGTCTGGTACCTGCTGAGGAAGCAC
TGGATTGCCAACAACCTTTTTGGCCTGGCCTTCTCCCTTAATGGAGTAGAGCTCCTGCACCTCAACAATGTCAGCACTGGCTGCATCCTG
CTGGGCGGACTCTTCATCTACGATGTCTTCTGGGTATTTGGCACCAATGTGATGGTGACAGTGGCCAAGTCCTTCGAGGCACCAATAAAA
TTGGTGTTTCCCCAGGATCTGCTGGAGAAAGGCCTCGAAGCAAACAACTTTGCCATGCTGGGACTTGGAGATGTCGTCATTCCAGGGATC
TTCATTGCCTTGCTGCTGCGCTTTGACATCAGCTTGAAGAAGAATACCCACACCTACTTCTACACCAGCTTTGCAGCCTACATCTTCGGC
CTGGGCCTTACCATCTTCATCATGCACATCTTCAAGCATGCTCAGCCTGCCCTCCTATACCTGGTCCCCGCCTGCATCGGTTTTCCTGTC
CTGGTGGCGCTGGCCAAGGGAGAAGTGACAGAGATGTTCAGCTACGAGTCCTCGGCGGAAATCCTGCCTCATACCCCGAGGCTCACCCAC
TTCCCCACAGTCTCGGGCTCCCCAGCCAGCCTGGCCGACTCCATGCAGCAGAAGCTAGCTGGCCCTCGCCGCCGGCGCCCGCAGAATCCC
AGCGCCATTTATGAGGAGTCAAATCCTAAGGATCCAGCGGCAGTGACAGAATCCAAAGAGGGAACAGAGGCATCAGCATCGAAGGGGCTG
GAGAAGAAAGAGAAATGATGCAGCTGGTGCCCGAGCCTCTCAGGGCCAGACCAGACAGATGGGGGCTGGGCCCACACAGGCGTGCACCGG
TAGAGGGCACAGGAGGCCAAGGGCAGCTCCAGGACAGGGCAGGGGGCAGCAGGATACCTCCAGCCAGGCCTCTGTGGCCTCTGTTTCCTT
CTCCCTTTCTTGGCCCTCCTCTGCTCCTCCCCACACCCTGCAGGCAAAAGAAACCCCCAGCTTCCCCCCTCCCCGGGAGCCAGGTGGGAA
AAGTGGGTGTGATTTTTAGATTTTGTATTGTGGACTGATTTTGCCTCACATTAAAAACTCATCCCATGGCCAGGGCGGGCCACTGTGCTC

>61806_61806_12_OSBPL2-HM13_OSBPL2_chr20_60847315_ENST00000439951_HM13_chr20_30115287_ENST00000398174_length(amino acids)=409AA_BP=44
MSKITMPIAFNEPLSFLQRITEYMEHVYLIHRASCQPQPLERMQNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSM
YFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGV
ELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNT
HTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQ

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Fusion Gene PPI Analysis for OSBPL2-HM13

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for OSBPL2-HM13

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for OSBPL2-HM13

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	OSBPL2	C3711374	Nonsyndromic Deafness	2	CLINGEN
Hgene	OSBPL2	C4084712	DEAFNESS, AUTOSOMAL DOMINANT 67	1	CTD_human;GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:OSBPL2-HM13 (FusionGDB2 ID:HG9885TG81502)

Fusion Gene Summary for OSBPL2-HM13

Fusion Gene ORF analysis for OSBPL2-HM13

Fusion Genomic Features for OSBPL2-HM13

Fusion Protein Features for OSBPL2-HM13

Fusion Gene Sequence for OSBPL2-HM13

Fusion Gene PPI Analysis for OSBPL2-HM13

Related Drugs for OSBPL2-HM13

Related Diseases for OSBPL2-HM13

Fusion Gene Studies
in Kim Lab