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	Fusion Gene Summary
	Fusion Gene Breakpoints
	Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Geness
	Fusion Genomic Features
	Fusion Gene ORF Annotations
	Fusion Protein Retained/Non-Retained Functional Features
	Fusion Transcript Sequences
	Fusion Protein Sequences
	Personalized Fusion Protein Sequences
	Fusion Gene Expressed Samples
	Related Drugs

Fusion gene:ARHGAP44_ZSWIM7 (FusionGDB2 ID:HG9912TG125150)

Fusion Gene Summary for ARHGAP44_ZSWIM7

Fusion gene summary

Fusion gene information	Fusion gene name: ARHGAP44_ZSWIM7
	Fusion gene ID: hg9912tg125150
		Hgene	Tgene
	Gene symbol	ARHGAP44	ZSWIM7
	Gene ID	9912	125150
	Gene name	Rho GTPase activating protein 44	zinc finger SWIM-type containing 7
	Synonyms	NPC-A-10\|RICH2	ODG10\|SPGF71\|SWS1
	Cytomap	17p12	17p12
	Type of gene	protein-coding	protein-coding
	Description	rho GTPase-activating protein 44Rho-type GTPase-activating protein RICH2RhoGAP interacting with CIP4 homologs protein 2rho GTPase-activating protein RICH2	zinc finger SWIM domain-containing protein 7SWIM domain-containing and Srs2-interacting protein 1 homologSWIM-type zinc finger domain-containing protein 7
	Modification date	20240403	20240407
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000262444, ENST00000340825, ENST00000379672, ENST00000578087,
Fusion gene scores	* DoF score	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 13 X 11 X 8=1144	* DoF score (Degree of Frequency) = # partners X # break points X # disease types 1 X 3 X 5=15
	# samples	17	6
	** MAII score	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(17/114410)=-2.75048040064069 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score10) log2(6/1510)=2 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ARHGAP44 [Title/Abstract] AND ZSWIM7 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ARHGAP44(12832363)-ZSWIM7(15884458), # samples:1

Fusion gene breakpoints across ARHGAP44 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across ZSWIM7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Breakpoints for ARHGAP44_ZSWIM7

RNA-seq based exon junction arranged fusion gene breakpoints from 8 resources (TCGA, CCLE, cBioPortal, GenBank, ChimerDB, ChimerKB, ChildHoodFusions, and GTEx). For the expressed sample information, go to Fusion Gene Sample section.

Hgene	Hchr	Hbp	Tgene	Tchr	Tbp
ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458
ARHGAP44	chr17	12929046	ZSWIM7	chr17	15981144

DNA-seq based exon junction arranged fusion gene breakpoints from dbVar. For the expressed sample information, go to Fusion Gene Sample section.

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

SV type

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Tumorigenic MoA (Mechanism of Action) Scenarios of Fusion Genes for ARHGAP44_ZSWIM7

To generate these tumorigenic scenario annotations, we implemented a deduction-first, retrieval-later computational framework. The pipeline first applies rule-guided reasoning across ten core mechanistic categories (M1–M10) derived from fusion gene biology to infer candidate mechanisms, tumorigenic scenarios, targeting points, and targeting backgrounds. To ensure empirical accountability, a governed Python workflow retrieves literature candidates via NCBI E-utilities and Europe PMC using tiered searches. Using JSON Schema-constrained LLM evidence judges (GPT-5.6 Luna and Terra), retrieved articles are evaluated for specificity and confidence without de novo PMID generation. This produces two distinct versions: a strict version restricted to high- or medium-confidence fusion-specific evidence, and an extended version incorporating broader gene-, pathway-, and contextual evidence.

* We have 10 tumorigenic mechanism categories of fusion genes as shown below.

Constitutively Active Kinases, Catalytic Domain Dysregulation, & Transmembrane Ligand Fusions	Aberrant Chimeric Transcription Factor / Fusion Transcription Factor Activity	Epigenetic Reprogramming / Histone Modifier Dysregulation	Chromatin Remodeling Dysregulation	Condensate-Driven Transcriptional Rewiring / LLP	Promoter / Enhancer Hijacking	Dominant-Negative Antagonism	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation	Subcellular Mislocalization / Spatial Dysregulation	Nuclear Body / Sub-organellar Architecture Disruption & Differentiation Blockade

* Strict version: Restricted to high- or medium-confidence fusion-specific evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
ARHGAP44-ZSWIM7	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation M8		Disruption of ZSWIM7 (SWS1) impairs the Shu complex, disabling homologous recombination repair of damaged replication forks.		PARP inhibitors (olaparib, talazoparib); platinum chemotherapy		Homologous recombination-deficient solid tumors

* Extended version: Includes all strict-level fusion evidence plus broader gene-, pathway-, and low-confidence contextual evidence.

Fusion Gene Name	Mechanism Category	Mechanism PubMed	Tumorigenic Scenarios	Tumorigenic Scenario PubMed	Targeting Points	Targeting PubMed	Mechanism Background	Mechanism Background PubMed
ARHGAP44-ZSWIM7	Cell Cycle / Checkpoint Bypass / RNA Processing Dysregulation M8		Disruption of ZSWIM7 (SWS1) impairs the Shu complex, disabling homologous recombination repair of damaged replication forks.	Evidence level: Indirect gene evidence; Confidence: Medium; PMID: 40991243; Title: SWS1-complex in premature ovarian insufficiency: SWSAP1 as a new POI gene.	PARP inhibitors (olaparib, talazoparib); platinum chemotherapy		Homologous recombination-deficient solid tumors	Evidence level: Limited indirect gene evidence; Confidence: Low; PMID: 33006389; Title: Prevalence of comprehensive DNA damage repair gene germline mutations in Chinese prostate cancer patients.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

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Fusion Genomic Features for ARHGAP44_ZSWIM7

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of In-frame fusion genes. FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ARHGAP44	chr17	12832363	+	ZSWIM7	chr17	15884458	-	5.71e-08	1.00e+00
ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-	5.62e-05	1.00e+00

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5UTR-3CSD fusion genes (N-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence) of 5CDS-3UTR fusion genes (C-truncated cases).

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of six genomic regulatory feature tracks across a ±5 kb window centered on the fusion breakpoints. We input the breakpoint sequences into AlphaGenome and obtained predicted genome tracks at single-base-pair resolution for each modality by running a single forward pass over the reference sequence. Specifically, for each breakpoint, AlphaGenome processed and returned predicted track data across diverse modalities, which were then averaged across all tracks within each output type and visualized across the ±5 kb window. The left panel shows the 5'-gene breakpoint ±5 kb area, and the right panel shows the 3'-gene breakpoint area, with tracks grouped by category: chromatin accessibility (DNase-seq, ATAC-seq), active transcription (RNA-seq, CAGE), and chromatin binding (ChIP-Histone, ChIP-TF).

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Fusion Gene ORF Annotations for ARHGAP44_ZSWIM7

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000262444	ENST00000399280	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
5CDS-5UTR	ENST00000340825	ENST00000399280	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
5CDS-5UTR	ENST00000379672	ENST00000399280	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
In-frame	ENST00000262444	ENST00000399277	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
In-frame	ENST00000340825	ENST00000399277	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
In-frame	ENST00000379672	ENST00000399277	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-

ORFfinder Result Based On The Fusion Transcript Sequences of the In-frame Fusion Genes.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	Seq length (transcript)	Seq length (peptide)
ENST00000262444	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	661	267
ENST00000340825	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	882	267
ENST00000379672	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	882	1545

ORFfinder Result Based On The Fusion Transcript Sequences of the 5UTR-3CDS Fusion Genes for N-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

ORFfinder Result Based On The Fusion Transcript Sequences of the 5CDS-3UTR Fusion Genes for C-Truncated Protein Search.

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

Seq length
(transcript)

Seq length
(peptide)

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of In-frame Fusion Genes. DeepORF is a Coding Potential Classifier Based on Convolutional Neural Network by Comparing the Real Ribo-seq Data. If the No-coding Score < 0.5 and Coding Score > 0.5, Then The In-frame Fusion Transcript is Predicted as Being Likely Translated.

Henst	Tenst	Hgene	Hchr	Hbp	Tgene	Tchr	Tbp	No-coding score	Coding score
ENST00000262444	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	9.13e-03	9.91e-01
ENST00000340825	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	6.80e-03	9.93e-01
ENST00000379672	ENST00000399277	ARHGAP44	chr17	12832363	ZSWIM7	chr17	15884458	6.80e-03	9.93e-01

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5UTR-3CDS Fusion Genes (Potential N-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

DeepORF Prediction of The Coding Potential Based on The Fusion Transcript Sequence of 5CDS-3UTR Fusion Genes (Potential C-Truncated Proteins).

Henst

Tenst

Hgene

Hchr

Hbp

Tgene

Tchr

Tbp

No-coding score

Coding score

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Fusion Protein Retained/Non-Retained Functional Features for ARHGAP44_ZSWIM7

Protein Level Annotation from FGviewer
* Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at download page. Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features (visualization across fusion protein length).

No matching images found for ${hg}_${tg}.

- In-frame and retained protein feature among the 13 regional features (texts).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

ZSWIM7

chr17:12832363

chr17:15884458

ENST00000399277

Q19AV6

66_114

67.0

141.0

Zinc finger

SWIM-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- Retained PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Hgene

Hbp

Tgene

Tbp

ENST

UniProt

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Fusion Transcript Sequence for ARHGAP44_ZSWIM7

In-frame Fusion Transcript Sequences.

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458 length=2370nt 
 Breakpoint=661nt
GAGCCATGTAACCCTGCGGCGGGCTCCGGGCTGCTCCGTCCTTCCCCAGCTCCCGGGCTAGCGCGGCAGCGGGGCCACGATGAAGAAGCAGTTCAATCGCATGCGCCAGCTGGCCAACCAGACGGTGGGCAGGGCTGAAAAGACAGAAGT
TTTGAGTGAAGACCTTCTTCAGGTGGAGAAGCGTCTGGAGCTGGTGAAACAGGTGTCCCACAGCACGCACAAGAAGCTCACCGCATGTCTGCAGGGCCAGCAAGGGGCAGAGGCTGACAAGCGCTCCAAAAAGTTGCCTTTGACAACACT
GGCTCAGTGTCTGATGGAGGGGTCAGCTATCCTGGGAGATGACACACTTCTTGGGAAGATGCTGAAACTCTGTGGAGAGACGGAGGACAAGCTGGCTCAGGAGCTGATACATTTTGAGTTGCAAGTAGAGAGAGACGTGATTGAGCCCCT
GTTTTTGCTGGCGGAGGTGGAAATCCCAAATATTCAAAAGCAGAGGAAACACTTAGCCAAGTTGGTGCTGGACATGGATTCCTCACGAACCAGGTGGCAGCAGACTTCCAAGTCTTCAGGTTTGTCCAGCAGCTTACAGCCTGCGGGTGC
CAAGGCTGATGCCCTCAGGGAAGAAATGGAAGAGGCTGCCAACAGAGTGGAGATTTGCAGGGTCCTTGGAAGTTCCAGTAAAACATACACATGTTTGGCTTCTTGTCATTACTGTTCATGTCCTGCATTTGCATTCTCAGTGCTACGGAA
GAGTGACAGCATCCTGTGCAAGCATCTCTTGGCAGTTTACCTGAGTCAGGTTATGAGGACCTGTCAGCAGCTAAGTGTCTCTGACAAGCAGTTGACTGACATATTATTGATGGAGAAGAAACAAGAAGCATAAAAGGTACAGATTGAGCA
TCATTCTTTCAAAATAGAATCCTGTCAAGAAATGCATTGAAAGCGTCATGATTCACATGGAAAAGAGGTGAAATGGATCTTCAGACACTTCATGTTACTGTCCCTTTTCCCTCCAGGACTGCAGGAGGTGCTGTGGGTTGGAGCCGTGGG
CTGTGGAGGGTTTGTGTATGATGAGAAGCCCTGTACAGTCTTGTCAAGAAATACCCTGAGCCAGTCTCTGAGACGCTTCGGTAAAAAATGTCCCTGGATGGAATCAAGATTTTAAATTCAAATAAAGCCTAATATCATGTTGTGTCCACA
TTATTTAGTCTTTTTTTTTTTCTTTTGAGATGGAGTCTCACTTTGTCGCCCAGGCTGGGGTGCAGTGGCGTGATCTCAGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACA
GGTACCCGCCACCATGCCCGGCTAAATTTTTGTATTTTTTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCCATCTCCTGACCTAGTGGTCTGCCCGCCTCGACCTCCCAAAGTGCTGGAATTACATGCATGAGCCA
CTGCGCCTGACCCTATTTAGTCTTAAGTAACTAACTGAATTACTAGTAATTTTTAAAAGGTTGGAATGGTGGGCCAAACAGTAAGATGAAGTTTCGACGAGTAGGTCAGTTCTTTTCCTTGGGTCCAGGAAACTATTGAGCAGCAACAGA
AGATCAGAGCAGAGATGTGGCTAAACAGTAGCAGGTATGAAAAGACTTAGAGGTTCTGGTTTCTGTAAGCTTCAAATATCTGTGATGCTTGTGCCAAAACAGCTTAAGTAGACTGTATTGTTTGAGAGTTAGTATCGAGAACAAGGGAAG
AACTGGTTTCACTCTGCACTTCTGATCTTTACAACAGGGCAATTGAAGGAACAGACTAAAAATCGTGTCCTGGAAGGAAACTACAGGTACTACCAGGGATTTTCAGTCTGAAGAAGAAAAGACAAAATAGATGACAGAAGGAGTATTAGA
AGGGAGAGCGATGAGACTCAGTTGGACACCGAGAGAGCAAAGAAGCAATAATACGTGAAGATGAAAATGAAATCAATTTCAGCATAAGAAGACAAGAACTTATGGTAAAGCTGCCCACAGCCAGAAGAGGATCCTAGAAGGACAGGAATT
CCCTGTCTGCAGCATTTCATAAGCATGTAATATTGTTGCAGGGATACTGCAGAAGGAGTTGAAGCAGTGGACAGACAGATGATATAGGTGATTTTACAGCCTAAGAAAGCCCTGTGCTTGTGCCCCCAAAACATGAGGTGCTAGTGAATG
AATGCTGGGGGAAAGCCCAGGGCCTAGGTGTTGCAATGTTCTGTGGTTGGCAGATGCTTTTTGTTTTGTTAAAAAGTGCAACAGATAAAATTTATCAATACTTTTCTGCTACTCAGGAAA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458 length=2591nt 
 Breakpoint=882nt
GACTGGGAGCAGGCAGCCCGGGCGGAGCGGGCCGGTGCCGAGGACGGCCCCAGGCATTGCTCTGCCCCGGGCATTGCGCGGCGCGCGTGAGGGGGATGCGGCAGGAGGCGGCGCGGCGGGAGGAGTAGGCGGCGGCGCCCTCGGGAGGGA
GCTGCGCGCGGGCCAGACGGCGCCCGGAGGCTCCGCAGTGCCGCCGCCGTCGCCCGGGAGGCTCCGCGCGGGAGCCATGTAACCCTGCGGCGGGCTCCGGGCTGCTCCGTCCTTCCCCAGCTCCCGGGCTAGCGCGGCAGCGGGGCCACG
ATGAAGAAGCAGTTCAATCGCATGCGCCAGCTGGCCAACCAGACGGTGGGCAGGGCTGAAAAGACAGAAGTTTTGAGTGAAGACCTTCTTCAGGTGGAGAAGCGTCTGGAGCTGGTGAAACAGGTGTCCCACAGCACGCACAAGAAGCTC
ACCGCATGTCTGCAGGGCCAGCAAGGGGCAGAGGCTGACAAGCGCTCCAAAAAGTTGCCTTTGACAACACTGGCTCAGTGTCTGATGGAGGGGTCAGCTATCCTGGGAGATGACACACTTCTTGGGAAGATGCTGAAACTCTGTGGAGAG
ACGGAGGACAAGCTGGCTCAGGAGCTGATACATTTTGAGTTGCAAGTAGAGAGAGACGTGATTGAGCCCCTGTTTTTGCTGGCGGAGGTGGAAATCCCAAATATTCAAAAGCAGAGGAAACACTTAGCCAAGTTGGTGCTGGACATGGAT
TCCTCACGAACCAGGTGGCAGCAGACTTCCAAGTCTTCAGGTTTGTCCAGCAGCTTACAGCCTGCGGGTGCCAAGGCTGATGCCCTCAGGGAAGAAATGGAAGAGGCTGCCAACAGAGTGGAGATTTGCAGGGTCCTTGGAAGTTCCAGT
AAAACATACACATGTTTGGCTTCTTGTCATTACTGTTCATGTCCTGCATTTGCATTCTCAGTGCTACGGAAGAGTGACAGCATCCTGTGCAAGCATCTCTTGGCAGTTTACCTGAGTCAGGTTATGAGGACCTGTCAGCAGCTAAGTGTC
TCTGACAAGCAGTTGACTGACATATTATTGATGGAGAAGAAACAAGAAGCATAAAAGGTACAGATTGAGCATCATTCTTTCAAAATAGAATCCTGTCAAGAAATGCATTGAAAGCGTCATGATTCACATGGAAAAGAGGTGAAATGGATC
TTCAGACACTTCATGTTACTGTCCCTTTTCCCTCCAGGACTGCAGGAGGTGCTGTGGGTTGGAGCCGTGGGCTGTGGAGGGTTTGTGTATGATGAGAAGCCCTGTACAGTCTTGTCAAGAAATACCCTGAGCCAGTCTCTGAGACGCTTC
GGTAAAAAATGTCCCTGGATGGAATCAAGATTTTAAATTCAAATAAAGCCTAATATCATGTTGTGTCCACATTATTTAGTCTTTTTTTTTTTCTTTTGAGATGGAGTCTCACTTTGTCGCCCAGGCTGGGGTGCAGTGGCGTGATCTCAG
CTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTACCCGCCACCATGCCCGGCTAAATTTTTGTATTTTTTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATG
GTCTCCATCTCCTGACCTAGTGGTCTGCCCGCCTCGACCTCCCAAAGTGCTGGAATTACATGCATGAGCCACTGCGCCTGACCCTATTTAGTCTTAAGTAACTAACTGAATTACTAGTAATTTTTAAAAGGTTGGAATGGTGGGCCAAAC
AGTAAGATGAAGTTTCGACGAGTAGGTCAGTTCTTTTCCTTGGGTCCAGGAAACTATTGAGCAGCAACAGAAGATCAGAGCAGAGATGTGGCTAAACAGTAGCAGGTATGAAAAGACTTAGAGGTTCTGGTTTCTGTAAGCTTCAAATAT
CTGTGATGCTTGTGCCAAAACAGCTTAAGTAGACTGTATTGTTTGAGAGTTAGTATCGAGAACAAGGGAAGAACTGGTTTCACTCTGCACTTCTGATCTTTACAACAGGGCAATTGAAGGAACAGACTAAAAATCGTGTCCTGGAAGGAA
ACTACAGGTACTACCAGGGATTTTCAGTCTGAAGAAGAAAAGACAAAATAGATGACAGAAGGAGTATTAGAAGGGAGAGCGATGAGACTCAGTTGGACACCGAGAGAGCAAAGAAGCAATAATACGTGAAGATGAAAATGAAATCAATTT
CAGCATAAGAAGACAAGAACTTATGGTAAAGCTGCCCACAGCCAGAAGAGGATCCTAGAAGGACAGGAATTCCCTGTCTGCAGCATTTCATAAGCATGTAATATTGTTGCAGGGATACTGCAGAAGGAGTTGAAGCAGTGGACAGACAGA
TGATATAGGTGATTTTACAGCCTAAGAAAGCCCTGTGCTTGTGCCCCCAAAACATGAGGTGCTAGTGAATGAATGCTGGGGGAAAGCCCAGGGCCTAGGTGTTGCAATGTTCTGTGGTTGGCAGATGCTTTTTGTTTTGTTAAAAAGTGC
AACAGATAAAATTTATCAATACTTTTCTGCTACTCAGGAAA

>ARHGAP44_ZSWIM7_ENST00000379672_ENST00000399277_12832363_15884458 length=2591nt 
 Breakpoint=882nt
GACTGGGAGCAGGCAGCCCGGGCGGAGCGGGCCGGTGCCGAGGACGGCCCCAGGCATTGCTCTGCCCCGGGCATTGCGCGGCGCGCGTGAGGGGGATGCGGCAGGAGGCGGCGCGGCGGGAGGAGTAGGCGGCGGCGCCCTCGGGAGGGA
GCTGCGCGCGGGCCAGACGGCGCCCGGAGGCTCCGCAGTGCCGCCGCCGTCGCCCGGGAGGCTCCGCGCGGGAGCCATGTAACCCTGCGGCGGGCTCCGGGCTGCTCCGTCCTTCCCCAGCTCCCGGGCTAGCGCGGCAGCGGGGCCACG
ATGAAGAAGCAGTTCAATCGCATGCGCCAGCTGGCCAACCAGACGGTGGGCAGGGCTGAAAAGACAGAAGTTTTGAGTGAAGACCTTCTTCAGGTGGAGAAGCGTCTGGAGCTGGTGAAACAGGTGTCCCACAGCACGCACAAGAAGCTC
ACCGCATGTCTGCAGGGCCAGCAAGGGGCAGAGGCTGACAAGCGCTCCAAAAAGTTGCCTTTGACAACACTGGCTCAGTGTCTGATGGAGGGGTCAGCTATCCTGGGAGATGACACACTTCTTGGGAAGATGCTGAAACTCTGTGGAGAG
ACGGAGGACAAGCTGGCTCAGGAGCTGATACATTTTGAGTTGCAAGTAGAGAGAGACGTGATTGAGCCCCTGTTTTTGCTGGCGGAGGTGGAAATCCCAAATATTCAAAAGCAGAGGAAACACTTAGCCAAGTTGGTGCTGGACATGGAT
TCCTCACGAACCAGGTGGCAGCAGACTTCCAAGTCTTCAGGTTTGTCCAGCAGCTTACAGCCTGCGGGTGCCAAGGCTGATGCCCTCAGGGAAGAAATGGAAGAGGCTGCCAACAGAGTGGAGATTTGCAGGGTCCTTGGAAGTTCCAGT
AAAACATACACATGTTTGGCTTCTTGTCATTACTGTTCATGTCCTGCATTTGCATTCTCAGTGCTACGGAAGAGTGACAGCATCCTGTGCAAGCATCTCTTGGCAGTTTACCTGAGTCAGGTTATGAGGACCTGTCAGCAGCTAAGTGTC
TCTGACAAGCAGTTGACTGACATATTATTGATGGAGAAGAAACAAGAAGCATAAAAGGTACAGATTGAGCATCATTCTTTCAAAATAGAATCCTGTCAAGAAATGCATTGAAAGCGTCATGATTCACATGGAAAAGAGGTGAAATGGATC
TTCAGACACTTCATGTTACTGTCCCTTTTCCCTCCAGGACTGCAGGAGGTGCTGTGGGTTGGAGCCGTGGGCTGTGGAGGGTTTGTGTATGATGAGAAGCCCTGTACAGTCTTGTCAAGAAATACCCTGAGCCAGTCTCTGAGACGCTTC
GGTAAAAAATGTCCCTGGATGGAATCAAGATTTTAAATTCAAATAAAGCCTAATATCATGTTGTGTCCACATTATTTAGTCTTTTTTTTTTTCTTTTGAGATGGAGTCTCACTTTGTCGCCCAGGCTGGGGTGCAGTGGCGTGATCTCAG
CTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTACCCGCCACCATGCCCGGCTAAATTTTTGTATTTTTTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATG
GTCTCCATCTCCTGACCTAGTGGTCTGCCCGCCTCGACCTCCCAAAGTGCTGGAATTACATGCATGAGCCACTGCGCCTGACCCTATTTAGTCTTAAGTAACTAACTGAATTACTAGTAATTTTTAAAAGGTTGGAATGGTGGGCCAAAC
AGTAAGATGAAGTTTCGACGAGTAGGTCAGTTCTTTTCCTTGGGTCCAGGAAACTATTGAGCAGCAACAGAAGATCAGAGCAGAGATGTGGCTAAACAGTAGCAGGTATGAAAAGACTTAGAGGTTCTGGTTTCTGTAAGCTTCAAATAT
CTGTGATGCTTGTGCCAAAACAGCTTAAGTAGACTGTATTGTTTGAGAGTTAGTATCGAGAACAAGGGAAGAACTGGTTTCACTCTGCACTTCTGATCTTTACAACAGGGCAATTGAAGGAACAGACTAAAAATCGTGTCCTGGAAGGAA
ACTACAGGTACTACCAGGGATTTTCAGTCTGAAGAAGAAAAGACAAAATAGATGACAGAAGGAGTATTAGAAGGGAGAGCGATGAGACTCAGTTGGACACCGAGAGAGCAAAGAAGCAATAATACGTGAAGATGAAAATGAAATCAATTT
CAGCATAAGAAGACAAGAACTTATGGTAAAGCTGCCCACAGCCAGAAGAGGATCCTAGAAGGACAGGAATTCCCTGTCTGCAGCATTTCATAAGCATGTAATATTGTTGCAGGGATACTGCAGAAGGAGTTGAAGCAGTGGACAGACAGA
TGATATAGGTGATTTTACAGCCTAAGAAAGCCCTGTGCTTGTGCCCCCAAAACATGAGGTGCTAGTGAATGAATGCTGGGGGAAAGCCCAGGGCCTAGGTGTTGCAATGTTCTGTGGTTGGCAGATGCTTTTTGTTTTGTTAAAAAGTGC
AACAGATAAAATTTATCAATACTTTTCTGCTACTCAGGAAA

N-Truncated Transcript (5UTR-3CDS) Sequences

C-Truncated Transcript (5CDS-3UTR) Sequences

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Fusion Protein Sequence for ARHGAP44_ZSWIM7

In-frame Fusion Protein Sequences.

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458 length=267nt
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458 length=267nt
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000379672_ENST00000399277_12832363_15884458 length=1545nt
MKKQFNRMRQLANQTVGRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAK
KKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQ
PDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEI
VNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFR
FYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQ
FSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENA
CNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHP
DFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALE
TYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIF
DAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCP
CYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS

N-Truncated Protein (5UTR-3CDS) Sequences

C-Truncated Protein (5CDS-3UTR) Sequences

Top

Personalized Fusion Protein Sequence for ARHGAP44_ZSWIM7

TCGA Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

CCLE Kinase/DNA-binding Domain Mutated Fusion Protein Sequences

Num

Gene Group

Domain Loci

Fusion Protein ID

Fusion Gene Name

Partner

Mutated Residue in WT Protein

Seq. Length

Mutated Residue in Fusion Protein

TCGA All Mutated Fusion Protein Sequences

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.Q138E_267_Q138E length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKERKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.A186T_267_A186T length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEETANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.D28Y_267_D28Y length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEYLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.A178T_267_A178T length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADTLREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.R118I_267_R118I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVEIDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.E108D_267_E108D length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQDLIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.L54M_267_L54M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACMQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.R65C_267_R65C length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKCSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.V120M_267_V120M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDMIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.Q136E_267_Q136E length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIEKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.A52V_267_A52V length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTVCLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.G86R_267_G86R length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILRDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.T46M_267_T46M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSMHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.F125I_267_F125I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLILLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.F125I_267_F125I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLILLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.L179F_267_L179F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADAFREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.R153Q_267_R153Q length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSQTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.K104R_267_K104R length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDRLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.A52P_267_A52P length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTPCLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.R153Q_267_R153Q length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSQTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.Q107H_267_Q107H length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAHELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.M149I_267_M149I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDID
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.D103G_267_D103G length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEGKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.E181K_267_E181K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALRKEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.G99V_267_G99V length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCVETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.E100D;p.E129K_267_E100D;E129K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGDTEDKLAQELIHFELQVERDVIEPLFLLAKVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.I84F_267_I84F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAFLGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.L126M_267_L126M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFMLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.S43F_267_S43F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVFHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000262444_ENST00000399277_12832363_15884458_5-gene_p.E131K_267_E131K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVKIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.Q138E_267_Q138E length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKERKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.A186T_267_A186T length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEETANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.D28Y_267_D28Y length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEYLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.A178T_267_A178T length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADTLREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.R118I_267_R118I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVEIDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.E108D_267_E108D length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQDLIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.L54M_267_L54M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACMQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.R65C_267_R65C length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKCSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.V120M_267_V120M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDMIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.Q136E_267_Q136E length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIEKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.A52V_267_A52V length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTVCLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.G86R_267_G86R length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILRDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.T46M_267_T46M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSMHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.F125I_267_F125I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLILLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.F125I_267_F125I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLILLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.L179F_267_L179F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADAFREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.R153Q_267_R153Q length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSQTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.K104R_267_K104R length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDRLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.A52P_267_A52P length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTPCLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.R153Q_267_R153Q length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSQTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.Q107H_267_Q107H length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAHELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.M149I_267_M149I length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDID
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.D103G_267_D103G length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEGKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.E181K_267_E181K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALRKEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.G99V_267_G99V length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCVETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.E100D;p.E129K_267_E100D;E129K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGDTEDKLAQELIHFELQVERDVIEPLFLLAKVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.I84F_267_I84F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAFLGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.L126M_267_L126M length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFMLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.S43F_267_S43F length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVFHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

>ARHGAP44_ZSWIM7_ENST00000340825_ENST00000399277_12832363_15884458_5-gene_p.E131K_267_E131K length=267AA
MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKRSKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVKIPNIQKQRKHLAKLVLDMD
SSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA

Fusion Protein ID	Sample ID	Mutated Partner	AAchange in WT	Seq. Length	AAchange in Fusion
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-17-Z011-01A	5-gene	p.Q138E	267	Q138E
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-A5-A0G2-01A	5-gene	p.A186T	267	A186T
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AA-3864-01A	5-gene	p.D28Y	267	D28Y
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AA-3947-01A	5-gene	p.A178T	267	A178T
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AG-A002-01A	5-gene	p.R118I	267	R118I
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AG-A008-01A	5-gene	p.E108D	267	E108D
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AP-A051-01A	5-gene	p.L54M	267	L54M
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AP-A1DP-01A	5-gene	p.R65C	267	R65C
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-AX-A2HD-01A	5-gene	p.V120M	267	V120M
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-BT-A20J-01A	5-gene	p.Q136E	267	Q136E
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-C5-A8XH-01A	5-gene	p.A52V	267	A52V
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-D3-A3MV-06A	5-gene	p.G86R	267	G86R
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-D5-6540-01A	5-gene	p.T46M	267	T46M
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-DD-A1EE-01A	5-gene	p.F125I	267	F125I
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-DD-A1EF-01A	5-gene	p.F125I	267	F125I
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-EE-A20C-06A	5-gene	p.L179F	267	L179F
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-EE-A2MJ-06A	5-gene	p.R153Q	267	R153Q
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-EE-A3AH-06A	5-gene	p.K104R	267	K104R
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-EO-A1Y5-01A	5-gene	p.A52P	267	A52P
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-ER-A195-06A	5-gene	p.R153Q	267	R153Q
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-ER-A19F-06A	5-gene	p.Q107H	267	Q107H
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-F4-6570-01A	5-gene	p.M149I	267	M149I
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-FI-A2D5-01A	5-gene	p.D103G	267	D103G
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-FW-A3R5-06A	5-gene	p.E181K	267	E181K
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-G3-A25U-01A	5-gene	p.G99V	267	G99V
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-GC-A3WC-01A	5-gene	p.E100D;p.E129K	267	E100D;E129K
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-GN-A266-06A	5-gene	p.I84F	267	I84F
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-MF-A522-01A	5-gene	p.L126M	267	L126M
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-QK-AA3J-01A	5-gene	p.S43F	267	S43F
ENST00000262444_ENST00000399277_12832363_15884458	TCGA-RP-A695-06A	5-gene	p.E131K	267	E131K
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-17-Z011-01A	5-gene	p.Q138E	267	Q138E
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-A5-A0G2-01A	5-gene	p.A186T	267	A186T
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AA-3864-01A	5-gene	p.D28Y	267	D28Y
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AA-3947-01A	5-gene	p.A178T	267	A178T
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AG-A002-01A	5-gene	p.R118I	267	R118I
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AG-A008-01A	5-gene	p.E108D	267	E108D
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AP-A051-01A	5-gene	p.L54M	267	L54M
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AP-A1DP-01A	5-gene	p.R65C	267	R65C
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-AX-A2HD-01A	5-gene	p.V120M	267	V120M
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-BT-A20J-01A	5-gene	p.Q136E	267	Q136E
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-C5-A8XH-01A	5-gene	p.A52V	267	A52V
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-D3-A3MV-06A	5-gene	p.G86R	267	G86R
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-D5-6540-01A	5-gene	p.T46M	267	T46M
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-DD-A1EE-01A	5-gene	p.F125I	267	F125I
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-DD-A1EF-01A	5-gene	p.F125I	267	F125I
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-EE-A20C-06A	5-gene	p.L179F	267	L179F
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-EE-A2MJ-06A	5-gene	p.R153Q	267	R153Q
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-EE-A3AH-06A	5-gene	p.K104R	267	K104R
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-EO-A1Y5-01A	5-gene	p.A52P	267	A52P
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-ER-A195-06A	5-gene	p.R153Q	267	R153Q
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-ER-A19F-06A	5-gene	p.Q107H	267	Q107H
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-F4-6570-01A	5-gene	p.M149I	267	M149I
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-FI-A2D5-01A	5-gene	p.D103G	267	D103G
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-FW-A3R5-06A	5-gene	p.E181K	267	E181K
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-G3-A25U-01A	5-gene	p.G99V	267	G99V
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-GC-A3WC-01A	5-gene	p.E100D;p.E129K	267	E100D;E129K
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-GN-A266-06A	5-gene	p.I84F	267	I84F
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-MF-A522-01A	5-gene	p.L126M	267	L126M
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-QK-AA3J-01A	5-gene	p.S43F	267	S43F
ENST00000340825_ENST00000399277_12832363_15884458	TCGA-RP-A695-06A	5-gene	p.E131K	267	E131K

CCLE All Mutated Fusion Protein Sequences

Fusion Protein ID

Sample ID

Mutated Partner

AAchange in WT

Seq. Length

AAchange in Fusion

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Fusion Gene Exprssed Samples for ARHGAP44_ZSWIM7

RNA-seq based fusion gene expressed samples.

Source	Study	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB		SARC	TCGA-KD-A5QT-01A	ARHGAP44	chr17	12832363	-	ZSWIM7	chr17	15884458	-
ChimerDB		SARC	TCGA-KD-A5QT-01A	ARHGAP44	chr17	12832363	+	ZSWIM7	chr17	15884458	-
WashU		SARC	TCGA-KD-A5QT-01A	ARHGAP44	chr17	12832363	+	ZSWIM7	chr17	15884458	-
cBioPortal	SARC_TCGA_PAN_CAN_ATLAS_2018	SOFT_TISSUE	TCGA-KD-A5QT-01	ARHGAP44	chr17	12929046		ZSWIM7	chr17	15981144

DNA-seq based fusion gene expressed samples.

Source

Study

Disease

Sample

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

SV type

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Related Drugs for ARHGAP44_ZSWIM7

PubMed Abstract Search With ['A-B' AND 'drug'], ['A::B' AND 'drug']
* For more details on the Studied, Reported, Approved Drugs targeting this fusion gene, Go to FusionPub.

PMID

Fusion Gene Name

Drug

Study Title

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status