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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:BCL2L11-CCDC170 (FusionGDB2 ID:HG10018TG80129)

Fusion Gene Summary for BCL2L11-CCDC170

check button Fusion gene summary
Fusion gene informationFusion gene name: BCL2L11-CCDC170
Fusion gene ID: hg10018tg80129
HgeneTgene
Gene symbol

BCL2L11

CCDC170

Gene ID

10018

80129

Gene nameBCL2 like 11coiled-coil domain containing 170
SynonymsBAM|BIM|BODC6orf97|bA282P11.1
Cytomap('BCL2L11')('CCDC170')

2q13

6q25.1

Type of geneprotein-codingprotein-coding
Descriptionbcl-2-like protein 11BCL2-like 11 (apoptosis facilitator)bcl-2 interacting mediator of cell deathbcl-2 interacting protein Bimbcl-2-related ovarian death agonistcoiled-coil domain-containing protein 170
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000308659, ENST00000357757, 
ENST00000393253, ENST00000393256, 
ENST00000337565, ENST00000405953, 
Fusion gene scores* DoF score7 X 4 X 6=1687 X 13 X 7=637
# samples 920
** MAII scorelog2(9/168*10)=-0.900464326449086
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/637*10)=-1.67129337248158
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BCL2L11 [Title/Abstract] AND CCDC170 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBCL2L11(111907724)-CCDC170(151894309), # samples:2
Anticipated loss of major functional domain due to fusion event.BCL2L11-CCDC170 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L11-CCDC170 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L11-CCDC170 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BCL2L11-CCDC170 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBCL2L11

GO:0008630

intrinsic apoptotic signaling pathway in response to DNA damage

11546872

HgeneBCL2L11

GO:0031334

positive regulation of protein complex assembly

21041309

HgeneBCL2L11

GO:0034976

response to endoplasmic reticulum stress

22761832

HgeneBCL2L11

GO:2000271

positive regulation of fibroblast apoptotic process

11997495


check buttonFusion gene breakpoints across BCL2L11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CCDC170 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1323-01ABCL2L11chr2

111907724

+CCDC170chr6

151894309

+


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Fusion Gene ORF analysis for BCL2L11-CCDC170

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000308659ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
5CDS-intronENST00000357757ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
5CDS-intronENST00000393253ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
5CDS-intronENST00000393256ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000308659ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000308659ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000357757ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000357757ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000393253ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000393253ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000393256ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
In-frameENST00000393256ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-3CDSENST00000337565ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-3CDSENST00000337565ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-3CDSENST00000405953ENST00000239374BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-3CDSENST00000405953ENST00000367290BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-intronENST00000337565ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+
intron-intronENST00000405953ENST00000544131BCL2L11chr2

111907724

+CCDC170chr6

151894309

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393253BCL2L11chr2111907724+ENST00000239374CCDC170chr6151894309+49365161261889587
ENST00000393253BCL2L11chr2111907724+ENST00000367290CCDC170chr6151894309+49575161261910594
ENST00000357757BCL2L11chr2111907724+ENST00000239374CCDC170chr6151894309+52067861262159677
ENST00000357757BCL2L11chr2111907724+ENST00000367290CCDC170chr6151894309+52277861262180684
ENST00000308659BCL2L11chr2111907724+ENST00000239374CCDC170chr6151894309+50266061261979617
ENST00000308659BCL2L11chr2111907724+ENST00000367290CCDC170chr6151894309+50476061262000624
ENST00000393256BCL2L11chr2111907724+ENST00000239374CCDC170chr6151894309+51917711112144677
ENST00000393256BCL2L11chr2111907724+ENST00000367290CCDC170chr6151894309+52127711112165684

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393253ENST00000239374BCL2L11chr2111907724+CCDC170chr6151894309+0.0007104210.9992895
ENST00000393253ENST00000367290BCL2L11chr2111907724+CCDC170chr6151894309+0.0007901480.9992099
ENST00000357757ENST00000239374BCL2L11chr2111907724+CCDC170chr6151894309+0.0010073660.9989926
ENST00000357757ENST00000367290BCL2L11chr2111907724+CCDC170chr6151894309+0.0011375140.9988625
ENST00000308659ENST00000239374BCL2L11chr2111907724+CCDC170chr6151894309+0.0010911450.9989089
ENST00000308659ENST00000367290BCL2L11chr2111907724+CCDC170chr6151894309+0.001120610.9988794
ENST00000393256ENST00000239374BCL2L11chr2111907724+CCDC170chr6151894309+0.0010036860.9989963
ENST00000393256ENST00000367290BCL2L11chr2111907724+CCDC170chr6151894309+0.0011360360.99886394

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Fusion Genomic Features for BCL2L11-CCDC170


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BCL2L11chr2111907724+CCDC170chr6151894308+0.0003004470.9996996
BCL2L11chr2111907724+CCDC170chr6151894308+0.0003004470.9996996

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BCL2L11-CCDC170


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:111907724/chr6:151894309)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000357757+34148_162166173.0MotifNote=BH3
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000393256+34148_162166199.0MotifNote=BH3
TgeneCCDC170chr2:111907724chr6:151894309ENST00000239374411360_418258716.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC170chr2:111907724chr6:151894309ENST00000239374411478_656258716.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC170chr2:111907724chr6:151894309ENST00000239374411355_591258716.0RegionRequired for binding to microtubules and Golgi apparatus location

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000308659+45148_162106139.0MotifNote=BH3
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000337565+14148_1620113.0MotifNote=BH3
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000393253+34148_1627686.0MotifNote=BH3
HgeneBCL2L11chr2:111907724chr6:151894309ENST00000405953+13148_1620113.0MotifNote=BH3
TgeneCCDC170chr2:111907724chr6:151894309ENST0000023937441130_286258716.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for BCL2L11-CCDC170


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9343_9343_1_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000308659_CCDC170_chr6_151894309_ENST00000239374_length(transcript)=5026nt_BP=606nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACA
CAAACCCCAAGTCCTCCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAA
GCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATA
GAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTG
GTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACAT
CAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGA
ACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTT
TGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCA
TTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGG
GAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATT
TTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCAT
TGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCAT
AGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCA
AGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCC
AGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGT
GCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGA
CAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGT
CCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTT
TAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACACCCACAG
CAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGG
GAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTG
TCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATAC
AACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCC
GGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGC
CGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAG
CAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTT
TGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATT
TTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATG
GGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGA
GAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAG
GCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACAC
CTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCA
CCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGG
TCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAG
AGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTT
TCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAG
GATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATAT
ATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATAT
GAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCAT

>9343_9343_1_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000308659_CCDC170_chr6_151894309_ENST00000239374_length(amino acids)=617AA_BP=160
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQ
ERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQ
LEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRL
DVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKE
LNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKK

--------------------------------------------------------------
>9343_9343_2_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000308659_CCDC170_chr6_151894309_ENST00000367290_length(transcript)=5047nt_BP=606nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACA
CAAACCCCAAGTCCTCCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGGCAAGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAA
CTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAA
GAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAG
CTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTT
GAAAGATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGC
CATTTACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCAT
GTCTTTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCA
GCCTTAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGT
TAGATTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACC
ATGTGGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTG
GGACCAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGAT
GCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAA
TCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTA
CTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAG
GCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAA
AAAGTTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATC
AAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCA
GCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCA
ATATATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTT
CTATTTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCAT
ATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATT
AGGAGAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGC
AAAAAATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGG
GAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACA
AAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCA
AAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGAT
TATATTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTA
CAGACAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAA
AAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACC
ACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTAT
TTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGG
GGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGT
GGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTAT
GGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTT
AGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTG
ATATCATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATT
ACATTCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGAT
CTTTAACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATT
CTGTACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAAAGCCATTTTCTTCTTTGTTAA

>9343_9343_2_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000308659_CCDC170_chr6_151894309_ENST00000367290_length(amino acids)=624AA_BP=160
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQ
ERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQ
LEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRL
DVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKE
LNTCRDLHTELKAKLADTNELKASAWLHFIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTS

--------------------------------------------------------------
>9343_9343_3_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000357757_CCDC170_chr6_151894309_ENST00000239374_length(transcript)=5206nt_BP=786nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGGTAATCCTGAAGGCAATCACGGAGGTGAAGGGGACAGC
TGCCCCCACGGCAGCCCTCAGGGCCCGCTGGCCCCACCTGCCAGCCCTGGCCCTTTTGCTACCAGATCCCCGCTTTTCATCTTTATGAGA
AGATCCTCCCTGCTGTCTCGATCCTCCAGTGGGTATTTCTCTTTTGACACAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACA
CAAACCCCAAGTCCTCCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAA
GCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATA
GAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTG
GTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACAT
CAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGA
ACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTT
TGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCA
TTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGG
GAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATT
TTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCAT
TGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCAT
AGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCA
AGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCC
AGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGT
GCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGA
CAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGT
CCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTT
TAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACACCCACAG
CAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGG
GAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTG
TCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATAC
AACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCC
GGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGC
CGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAG
CAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTT
TGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATT
TTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATG
GGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGA
GAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAG
GCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACAC
CTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCA
CCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGG
TCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAG
AGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTT
TCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAG
GATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATAT
ATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATAT
GAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCAT

>9343_9343_3_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000357757_CCDC170_chr6_151894309_ENST00000239374_length(amino acids)=677AA_BP=220
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNH
YLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTK
AIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSL

--------------------------------------------------------------
>9343_9343_4_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000357757_CCDC170_chr6_151894309_ENST00000367290_length(transcript)=5227nt_BP=786nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGGTAATCCTGAAGGCAATCACGGAGGTGAAGGGGACAGC
TGCCCCCACGGCAGCCCTCAGGGCCCGCTGGCCCCACCTGCCAGCCCTGGCCCTTTTGCTACCAGATCCCCGCTTTTCATCTTTATGAGA
AGATCCTCCCTGCTGTCTCGATCCTCCAGTGGGTATTTCTCTTTTGACACAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACA
CAAACCCCAAGTCCTCCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGGCAAGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAA
CTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAA
GAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAG
CTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTT
GAAAGATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGC
CATTTACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCAT
GTCTTTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCA
GCCTTAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGT
TAGATTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACC
ATGTGGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTG
GGACCAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGAT
GCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAA
TCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTA
CTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAG
GCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAA
AAAGTTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATC
AAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCA
GCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCA
ATATATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTT
CTATTTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCAT
ATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATT
AGGAGAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGC
AAAAAATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGG
GAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACA
AAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCA
AAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGAT
TATATTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTA
CAGACAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAA
AAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACC
ACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTAT
TTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGG
GGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGT
GGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTAT
GGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTT
AGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTG
ATATCATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATT
ACATTCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGAT
CTTTAACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATT
CTGTACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAAAGCCATTTTCTTCTTTGTTAA

>9343_9343_4_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000357757_CCDC170_chr6_151894309_ENST00000367290_length(amino acids)=684AA_BP=220
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNH
YLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKASAWLHFI
KTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQML

--------------------------------------------------------------
>9343_9343_5_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393253_CCDC170_chr6_151894309_ENST00000239374_length(transcript)=4936nt_BP=516nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAA
GCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATA
GAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTG
GTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACAT
CAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGA
ACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTT
TGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCA
TTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGG
GAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATT
TTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCAT
TGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCAT
AGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCA
AGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCC
AGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGT
GCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGA
CAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGT
CCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTT
TAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACACCCACAG
CAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGG
GAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTG
TCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATAC
AACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCC
GGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGC
CGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAG
CAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTT
TGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATT
TTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATG
GGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGA
GAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAG
GCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACAC
CTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCA
CCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGG
TCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAG
AGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTT
TCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAG
GATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATAT
ATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATAT
GAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCAT

>9343_9343_5_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393253_CCDC170_chr6_151894309_ENST00000239374_length(amino acids)=587AA_BP=130
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTK
AIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSL

--------------------------------------------------------------
>9343_9343_6_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393253_CCDC170_chr6_151894309_ENST00000367290_length(transcript)=4957nt_BP=516nt
ACTTCGCTCCGCGCAGCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCC
GCCGCCGCCGCCGCCGCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCG
GTTCGCTGCGTTCCCGCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAAC
GCAAGAAAAAAAGACCAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGG
CCTCCCCAGCTCAGACCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCA
GAGATATGGATCGCCCAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCA
AAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGC
CTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTT
AGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGAC
AGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTT
CACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTT
TCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGAC
CAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTC
ATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTC
CTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGG
AACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACC
AATGAACTGAAGGCAAGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAA
CTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAA
GAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAG
CTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTT
GAAAGATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGC
CATTTACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCAT
GTCTTTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCA
GCCTTAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGT
TAGATTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACC
ATGTGGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTG
GGACCAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGAT
GCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAA
TCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTA
CTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAG
GCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAA
AAAGTTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATC
AAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCA
GCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCA
ATATATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTT
CTATTTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCAT
ATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATT
AGGAGAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGC
AAAAAATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGG
GAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACA
AAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCA
AAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGAT
TATATTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTA
CAGACAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAA
AAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACC
ACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTAT
TTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGG
GGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGT
GGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTAT
GGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTT
AGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTG
ATATCATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATT
ACATTCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGAT
CTTTAACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATT
CTGTACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAAAGCCATTTTCTTCTTTGTTAA

>9343_9343_6_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393253_CCDC170_chr6_151894309_ENST00000367290_length(amino acids)=594AA_BP=130
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKASAWLHFI
KTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQML

--------------------------------------------------------------
>9343_9343_7_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393256_CCDC170_chr6_151894309_ENST00000239374_length(transcript)=5191nt_BP=771nt
GCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCC
GCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCGGTTCGCTGCGTTCCC
GCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAACGCAAGAAAAAAAGAC
CAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGGCCTCCCCAGCTCAGA
CCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGGTAATCCTGAAGGCAATCACGGAGGTGAAGGGGACAGCTGCCCCCACGGCAGC
CCTCAGGGCCCGCTGGCCCCACCTGCCAGCCCTGGCCCTTTTGCTACCAGATCCCCGCTTTTCATCTTTATGAGAAGATCCTCCCTGCTG
TCTCGATCCTCCAGTGGGTATTTCTCTTTTGACACAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACACAAACCCCAAGTCCT
CCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCAGAGATATGGATCGCC
CAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCAAAAGAAGCTCTTGAA
AGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGCCTCCTGAAGAAAAGC
TCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTTAGGGAGAAAATCGCA
GCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGACAGCCGGGAAGAAAGC
AGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTTCACCAGAAAGCTCTC
CAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTTTCTGGAGGTGTTTTG
CGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGACCAGATGGCTGCCGAA
CTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTCATTGAGAACAAGACC
ATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTCCTCCGGCAGAAAATA
GCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGGAACTTGCAGAAGAAG
GTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACCAATGAACTGAAGATT
AAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTC
ATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGT
GAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTA
GGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACATCAGCATCACTTTGTT
ACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGAACACTGTATCTCTTG
AGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTTTGTGAATATTTTATG
CTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCATTAAAAACGCCTATT
ATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGGGAGATAATATTGGGA
GGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATTTTTAATTTACAACCT
TTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCATTGGCCCTGCCTCAAA
AGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATA
ACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCAT
TTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCA
TGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAG
CCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGACAGATTTACAAGTGT
AAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTG
CCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTT
TATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACACCCACAGCAATGGTACCTTTTT
AAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGGGAATCATATTCTTAA
CTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCT
CTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATACAACCAACCGTTCGTG
AGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCCGGTATGTTGGCATAT
GCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACT
GCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTC
TTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGC
ATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATTTTTTAAGCTTGACAA
ATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATGGGAAAAAATAGTGAA
GATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAG
AAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAG
CGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGC
TGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCAC
ATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTC
GGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTT
TGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAA
GATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAGGATTCATGTAAGAGA
CTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATATATGTTTATATAATAT
TTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATATGAAAAATGTTTGAAT
ATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCATATACACATTAAGTGT

>9343_9343_7_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393256_CCDC170_chr6_151894309_ENST00000239374_length(amino acids)=677AA_BP=220
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNH
YLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTK
AIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSL

--------------------------------------------------------------
>9343_9343_8_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393256_CCDC170_chr6_151894309_ENST00000367290_length(transcript)=5212nt_BP=771nt
GCCGCCTGGTCTGCAGTTTGTTGGAGCTCTGCGTCCAGCGCCGCTGCCGCTGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCC
GCCACTACCACCACTTGATTCTTGCAGCCACCCTGCGAACCCTGCCACACTGCGATCGCATCATCGCGGTATTCGGTTCGCTGCGTTCCC
GCCGCCACCGCCTCGGCGCCCTTTCTTGGCCCTTGTTCCCCCAAATGTCTGACTCTGACTCTCGGACTGAGAAACGCAAGAAAAAAAGAC
CAAATGGCAAAGCAACCTTCTGATGTAAGTTCTGAGTGTGACCGAGAAGGTAGACAATTGCAGCCTGCGGAGAGGCCTCCCCAGCTCAGA
CCTGGGGCCCCTACCTCCCTACAGACAGAGCCACAAGGTAATCCTGAAGGCAATCACGGAGGTGAAGGGGACAGCTGCCCCCACGGCAGC
CCTCAGGGCCCGCTGGCCCCACCTGCCAGCCCTGGCCCTTTTGCTACCAGATCCCCGCTTTTCATCTTTATGAGAAGATCCTCCCTGCTG
TCTCGATCCTCCAGTGGGTATTTCTCTTTTGACACAGACAGGAGCCCAGCACCCATGAGTTGTGACAAATCAACACAAACCCCAAGTCCT
CCTTGCCAGGCCTTCAACCACTATCTCAGTGCAATGGCTTCCATGAGGCAGGCTGAACCTGCAGATATGCGCCCAGAGATATGGATCGCC
CAAGAGTTGCGGCGTATTGGAGACGAGTTTAACGCTTACTATGCAAGGAGGGACCTGCTCAGTGCTGTAGAAGCAAAAGAAGCTCTTGAA
AGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGCCTCCTGAAGAAAAGC
TCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTTAGGGAGAAAATCGCA
GCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGACAGCCGGGAAGAAAGC
AGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTTCACCAGAAAGCTCTC
CAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTTTCTGGAGGTGTTTTG
CGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGACCAGATGGCTGCCGAA
CTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTCATTGAGAACAAGACC
ATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTCCTCCGGCAGAAAATA
GCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGGAACTTGCAGAAGAAG
GTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACCAATGAACTGAAGGCA
AGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAG
GAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAAC
ATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGG
GAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCAT
TCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTT
CATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGA
TCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGT
TCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGG
GAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGT
GACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACA
ACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGT
TTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGG
AGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAA
TAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAA
GATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAA
AAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTC
TCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCA
GTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACAC
CCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTT
TTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTT
TTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAA
ATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAAT
GAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCA
ATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCAT
AATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATC
TTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTT
TTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGAT
AAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGA
AAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGT
GACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAA
ACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTT
TCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTC
ACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTG
TATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAAT
TTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTA
TATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCC
AAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAG
AAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACA

>9343_9343_8_BCL2L11-CCDC170_BCL2L11_chr2_111907724_ENST00000393256_CCDC170_chr6_151894309_ENST00000367290_length(amino acids)=684AA_BP=220
MQPPCEPCHTAIASSRYSVRCVPAATASAPFLGPCSPKCLTLTLGLRNARKKDQMAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSL
QTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNH
YLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKS
LKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAE
NMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQR
KLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKASAWLHFI
KTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQML

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BCL2L11-CCDC170


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BCL2L11-CCDC170


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BCL2L11-CCDC170


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBCL2L11C0008313Cholangitis, Sclerosing1CTD_human
HgeneBCL2L11C0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneBCL2L11C0566602Primary sclerosing cholangitis1CTD_human
HgeneBCL2L11C2931456Prostate cancer, familial1CTD_human
HgeneBCL2L11C4722327PROSTATE CANCER, HEREDITARY, 11CTD_human