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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CHAF1A-ANKRD24 (FusionGDB2 ID:HG10036TG170961)

Fusion Gene Summary for CHAF1A-ANKRD24

check button Fusion gene summary
Fusion gene informationFusion gene name: CHAF1A-ANKRD24
Fusion gene ID: hg10036tg170961
HgeneTgene
Gene symbol

CHAF1A

ANKRD24

Gene ID

10036

170961

Gene namechromatin assembly factor 1 subunit Aankyrin repeat domain 24
SynonymsCAF-1|CAF1|CAF1B|CAF1P150|P150-
Cytomap('CHAF1A')('ANKRD24')

19p13.3

19p13.3

Type of geneprotein-codingprotein-coding
Descriptionchromatin assembly factor 1 subunit ACAF-1 subunit ACAF-I 150 kDa subunitCAF-I p150CTB-50L17.7chromatin assembly factor I (150 kDa)chromatin assembly factor I p150 subunithp150ankyrin repeat domain-containing protein 24
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000301280, ENST00000587368, 
Fusion gene scores* DoF score5 X 6 X 3=907 X 7 X 7=343
# samples 59
** MAII scorelog2(5/90*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/343*10)=-1.93021166984314
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CHAF1A [Title/Abstract] AND ANKRD24 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCHAF1A(4409756)-ANKRD24(4210055), # samples:1
Anticipated loss of major functional domain due to fusion event.CHAF1A-ANKRD24 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CHAF1A-ANKRD24 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CHAF1A-ANKRD24 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CHAF1A-ANKRD24 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCHAF1A

GO:0006335

DNA replication-dependent nucleosome assembly

14718166

HgeneCHAF1A

GO:0031497

chromatin assembly

8858152


check buttonFusion gene breakpoints across CHAF1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ANKRD24 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-5813-01ACHAF1Achr19

4409756

+ANKRD24chr19

4210055

+


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Fusion Gene ORF analysis for CHAF1A-ANKRD24

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000301280ENST00000595096CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
In-frameENST00000301280ENST00000262970CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
In-frameENST00000301280ENST00000318934CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
In-frameENST00000301280ENST00000600132CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
intron-3CDSENST00000587368ENST00000262970CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
intron-3CDSENST00000587368ENST00000318934CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
intron-3CDSENST00000587368ENST00000600132CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+
intron-3UTRENST00000587368ENST00000595096CHAF1Achr19

4409756

+ANKRD24chr19

4210055

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000301280CHAF1Achr194409756+ENST00000600132ANKRD24chr194210055+394110617136311186
ENST00000301280CHAF1Achr194409756+ENST00000318934ANKRD24chr194210055+394110617136311186
ENST00000301280CHAF1Achr194409756+ENST00000262970ANKRD24chr194210055+363210617136311187

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000301280ENST00000600132CHAF1Achr194409756+ANKRD24chr194210055+0.0104842470.9895158
ENST00000301280ENST00000318934CHAF1Achr194409756+ANKRD24chr194210055+0.0104842470.9895158
ENST00000301280ENST00000262970CHAF1Achr194409756+ANKRD24chr194210055+0.0125321920.98746777

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Fusion Genomic Features for CHAF1A-ANKRD24


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CHAF1Achr194409756+ANKRD24chr194210054+2.69E-070.99999976
CHAF1Achr194409756+ANKRD24chr194210054+2.69E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CHAF1A-ANKRD24


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:4409756/chr19:4210055)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315233_246320957.0MotifNote=PxVxL motif
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+3151_314320957.0RegionNote=Binds to CBX1 chromo shadow domain
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+3151_49320957.0RegionNote=Binds to PCNA
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820714_11103801237.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921320_5172901147.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921714_11102901147.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022320_5172901147.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022714_11102901147.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921308_3112901147.0Compositional biasNote=Poly-Pro
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022308_3112901147.0Compositional biasNote=Poly-Pro

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315323_453320957.0Compositional biasNote=Arg/Glu/Lys-rich
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315602_608320957.0Compositional biasNote=Poly-Glu
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315619_623320957.0Compositional biasNote=Poly-Asp
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315905_911320957.0Compositional biasNote=Poly-Glu
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315642_678320957.0RegionNote=Necessary for homodimerization and competence for chromatin assembly
HgeneCHAF1Achr19:4409756chr19:4210055ENST00000301280+315660_956320957.0RegionNote=Binds to p60
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820320_5173801237.0Coiled coilOntology_term=ECO:0000255
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820308_3113801237.0Compositional biasNote=Poly-Pro
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820114_1433801237.0RepeatNote=ANK 2
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820147_1763801237.0RepeatNote=ANK 3
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820180_2093801237.0RepeatNote=ANK 4
TgeneANKRD24chr19:4409756chr19:4210055ENST00000262970820213_2423801237.0RepeatNote=ANK 5
TgeneANKRD24chr19:4409756chr19:4210055ENST0000026297082081_1103801237.0RepeatNote=ANK 1
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921114_1432901147.0RepeatNote=ANK 2
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921147_1762901147.0RepeatNote=ANK 3
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921180_2092901147.0RepeatNote=ANK 4
TgeneANKRD24chr19:4409756chr19:4210055ENST00000318934921213_2422901147.0RepeatNote=ANK 5
TgeneANKRD24chr19:4409756chr19:4210055ENST0000031893492181_1102901147.0RepeatNote=ANK 1
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022114_1432901147.0RepeatNote=ANK 2
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022147_1762901147.0RepeatNote=ANK 3
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022180_2092901147.0RepeatNote=ANK 4
TgeneANKRD24chr19:4409756chr19:4210055ENST000006001321022213_2422901147.0RepeatNote=ANK 5
TgeneANKRD24chr19:4409756chr19:4210055ENST00000600132102281_1102901147.0RepeatNote=ANK 1


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Fusion Gene Sequence for CHAF1A-ANKRD24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16202_16202_1_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000262970_length(transcript)=3632nt_BP=1061nt
GGCGGCAGCAGCGGCGCGGGCGGGAGGGCGAAGAGCAGCGGCCGCCTGAGGGGAGCCCGCGCCTCCGCCGCCTGAGAGGAGGTCGAGCTG
CCGCCGGGGCGATGCTGGAGGAGCTGGAGTGCGGGGCGCCCGGCGCCAGGGGAGCCGCCACAGCCATGGATTGCAAAGATAGACCAGCTT
TTCCAGTTAAGAAGTTAATACAAGCCCGTCTGCCGTTTAAGCGCCTGAATCTTGTCCCAAAGGGGAAAGCCGATGACATGTCAGACGATC
AGGGTACTTCTGTGCAAAGTAAAAGCCCCGATTTAGAGGCCTCTTTGGACACCTTGGAAAACAACTGTCATGTGGGTTCTGACATAGACT
TTAGACCGAAACTTGTCAACGGGAAGGGTCCCTTAGATAACTTTTTAAGAAATAGAATCGAAACCAGTATTGGCCAGAGCACAGTCATCA
TTGATTTGACAGAGGACTCGAATGAGCAGCCAGACAGTCTTGTGGACCACAATAAACTAAATTCTGAAGCCTCTCCCTCCAGGGAGGCAA
TAAATGGCCAGCGAGAAGACACTGGGGATCAGCAGGGGTTGTTGAAGGCCATTCAGAACGACAAGTTGGCATTTCCTGGAGAGACCCTTT
CAGACATTCCTTGCAAAACAGAGGAGGAGGGTGTTGGCTGTGGAGGTGCAGGGAGGAGAGGCGACTCCCAGGAATGTTCGCCACGGAGCT
GCCCGGAGCTGACGAGTGGCCCGAGAATGTGCCCCAGAAAGGAGCAGGACAGTTGGAGTGAAGCTGGGGGCATCCTGTTCAAAGGGAAGG
TGCCTATGGTGGTCTTGCAGGACATCTTGGCTGTGAGACCACCGCAAATCAAGTCCCTTCCAGCCACACCCCAAGGCAAGAACATGACCC
CTGAGAGTGAGGTGCTGGAATCTTTCCCCGAAGAAGACTCTGTACTCAGCCATTCGTCCCTGAGCTCTCCCTCTTCCACCAGCTCGCCCG
AGGGGCCGCCTGCTCCCCCAAAGCAGCACAGCAGTACCAGTCCCTTCCCCACCTCCACGCCCCTCCGCAGAAACTCTATGTCCAGCCATG
GAAAGCAGGGGGCCCCCAAGAAGCGGAAGGCGCCTCCACCTCCCGCCAGCATTCCCATGCCGGATGATCGAGATGCCTATGAGGAGATCG
TGAGGCTGCGGCAGGAGAGGGGCCGCCTCCTGCAGAAGATCCGGGGCCTGGAACAGCACAAGGAACGGAGGCAGCAGGAGTCCCCGGAGG
CCAGCTCCCTGCACATCCTGGAGAGACAGGTGCAAGAGCTACAGCAGTTGCTGGTGGAGAGACAAGAGGAGAAGGAGAGCCTGGGACGGG
AGGTGGAGAGTTTGCAGAGCCGGCTGTCCCTGCTGGAGAACGAGCGGGAGAATACTAGCTATGACGTAACCACCCTGCAGGATGAGGAGG
GTGAGCTGCCTGACCTTCCAGGGGCCGAGGTGCTGCTGTCCAGACAACTCAGTCCGTCGGCCCAGGAACACCTGGCCTCGCTGCAGGAAC
AGGTGGCTGTGCTCACCAGACAGAACCAGGAACTGATGGAGAAGGTCCAGATCCTGGAGAACTTTGAGAAGGACGAGACACAGATGGAAG
TGGAAGCTTTGGCAGAGGTCATCCCTCTTGCCCTCTATGACTCTCTCCGGGCCGAGTTTGACCAGCTACGCAGGCAGCACGCTGAGGCCC
TGCAGGCCCTGAGGCAGCAGGAGACACGAGAGGTCCCCAGAGAAGAGGGGGCAGCCTGTGGGGAGAGTGAGGTTGCTGGAGCCACGGCCA
CCAAAAACGGGCCAACCCACATGGAGCTAAATGGCTCAGTGGCTCCAGAAACCAAAGTTAACGGAGCCGAGACCATAGATGAGGAGGCTG
CAGGAGATGAAACCATGGAAGCCAGGACTATGGAAGCTGAGGCCACGGGAGCCGAGGCCACGGGAGCTGAGGCCACAGGAGCCAAGGTCA
CAGAAACAAAACCCACAGGGGCTGAGGTCAGAGAAATGGAGACCACAGAAGAAGAAGCAAACATGGAAACTAAGCCCACAGGAGCTCAGG
CCACAGACACAGAGACCACGGGAGTGGAGGCCATGGGGGTGGAGGCCACAAAAACAAAAGCAGAGGAAGCAGAAATGCAGGCCTACGGAG
TGGGTGCTGGGCAAGCAGAGCCCCCAGTCACAGGGACCACAAACATGGAGGCCACGGGCTCTAGGGCCACAGGGATGGAATCCACAGGAG
TCAGTGCCACAGGTGTGGAGAACCCAGGGGTAGAGGCCACGGTCCCGGGGATCTCTGCTGGCCCCATCCTACATCCTGGTGCCGCAGAGG
CCTCGGAAAAGCTTCAAGTAGAGCTGGAGACCAGGATCCGTGGCTTGGAGGAGGCTCTCCGGCAGCGGGAGCGGGAGGCAGCTGCGGAGC
TGGAGGCGGCCCTGGGGAAGTGCGAGGCCGCGGAGGCCGAGGCAGGCCGGCTGCGAGAGCGTGTCCGCGAGGCCGAGGGCAGCGGGGCCA
GCGGGGGCGGTGGCGGTGACACCACACAGCTGCGGGCGGCCCTGGAGCAGGCCCGGGAGGACCTCCGAGACCGGGACTCCCGCCTGCGGG
AGCTGGAGGCGGCCTCGGCCTGCCTGGATGAGGCTCGGGCCAGCCGGCTGCTGGCGGAGGAGGAGGCGCGGGGCCTGCGGGCCGAGCTGG
CCCAGCGGGAGGAGGCGCGGCTGGAGCAGAGCCGGGAGCTGGAGGTTCTGCGGGAGCAGCTGGCCACGGCCAGGGCCACGGGGGAGCAGC
AGCGCACGGCGGCCGCGGAACTGGGCCGGGCACGGGACGCCGCTGAGGCCCGAGTGGCTGAGCTGCCTGCGGCCTGCGAGGAGGCGCGGC
AGGGCCTGGCCGAGCTGCGGGAGGCCTCCGAGGCCCTCCGCCAGTCCGTGGTGCCGGCCTCTGAGCACCGCCGGCTGCAGGAGGAGGCCC
TGGAGCTGCGGGGCCGGGCAGCCAGTCTGGAGCAGGAGGTGGTGGCCACGGGCAAGGAGGCCGCCCGGCTGCGCGCGGAGCTGGAGCGGG
AGCGTGTGTGCAGCGTGGCGCTCTCGGAGCACGAACGCATCGTGGGCACCCTGCAGGCCAACGTGGCCCAGCTGGAGGGGCAGCTGGAGG
AGCTGGGACGGCGGCATGAGAAGACCAGCGCAGAGGTCTTCCAGGTGCAGCGTGAGGCCCTGTTCATGAAGAGTGAGCGACACGCAGCCG
AGGCACAGCTGGCCACAGCAGAGCAGCAGCTACGGGGGCTACGGACCGAGGCGGAAAGGGCTCGCCAGGCCCAGAGCCGGGCCCAGGAGG
CTCTGGACAAGGCCAAGGAGAAGGACAAGAAGATCACAGAACTCTCCAAAGAAGTCTTCAATCTTAAGGAAGCCTTGAAGGAGCAGCCGG
CCGCCCTCGCCACCCCTGAGGTGGAGGCTCTCCGTGACCAGGTGAAGGATTTACAGCAGCAGCTGCAGGAAGCTGCCAGGGACCACTCCA
GCGTGGTGGCTTTGTACAGAAGCCACCTCCTATATGCCATTCAGGGCCAGATGGATGAAGATGTGCAGCGGATTCTCAGCCAGATTCTGC

>16202_16202_1_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000262970_length(amino acids)=1187AA_BP=330
MRGGRAAAGAMLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCH
VGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLA
FPGETLSDIPCKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATP
QGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRNSMSSHGKQGAPKKRKAPPPPASIPMPDDR
DAYEEIVRLRQERGRLLQKIRGLEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVT
TLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLR
RQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAE
ATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRAT
GMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVRE
AEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATA
RATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARL
RAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQA
QSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQR

--------------------------------------------------------------
>16202_16202_2_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000318934_length(transcript)=3941nt_BP=1061nt
GGCGGCAGCAGCGGCGCGGGCGGGAGGGCGAAGAGCAGCGGCCGCCTGAGGGGAGCCCGCGCCTCCGCCGCCTGAGAGGAGGTCGAGCTG
CCGCCGGGGCGATGCTGGAGGAGCTGGAGTGCGGGGCGCCCGGCGCCAGGGGAGCCGCCACAGCCATGGATTGCAAAGATAGACCAGCTT
TTCCAGTTAAGAAGTTAATACAAGCCCGTCTGCCGTTTAAGCGCCTGAATCTTGTCCCAAAGGGGAAAGCCGATGACATGTCAGACGATC
AGGGTACTTCTGTGCAAAGTAAAAGCCCCGATTTAGAGGCCTCTTTGGACACCTTGGAAAACAACTGTCATGTGGGTTCTGACATAGACT
TTAGACCGAAACTTGTCAACGGGAAGGGTCCCTTAGATAACTTTTTAAGAAATAGAATCGAAACCAGTATTGGCCAGAGCACAGTCATCA
TTGATTTGACAGAGGACTCGAATGAGCAGCCAGACAGTCTTGTGGACCACAATAAACTAAATTCTGAAGCCTCTCCCTCCAGGGAGGCAA
TAAATGGCCAGCGAGAAGACACTGGGGATCAGCAGGGGTTGTTGAAGGCCATTCAGAACGACAAGTTGGCATTTCCTGGAGAGACCCTTT
CAGACATTCCTTGCAAAACAGAGGAGGAGGGTGTTGGCTGTGGAGGTGCAGGGAGGAGAGGCGACTCCCAGGAATGTTCGCCACGGAGCT
GCCCGGAGCTGACGAGTGGCCCGAGAATGTGCCCCAGAAAGGAGCAGGACAGTTGGAGTGAAGCTGGGGGCATCCTGTTCAAAGGGAAGG
TGCCTATGGTGGTCTTGCAGGACATCTTGGCTGTGAGACCACCGCAAATCAAGTCCCTTCCAGCCACACCCCAAGGCAAGAACATGACCC
CTGAGAGTGAGGTGCTGGAATCTTTCCCCGAAGAAGACTCTGTACTCAGCCATTCGTCCCTGAGCTCTCCCTCTTCCACCAGCTCGCCCG
AGGGGCCGCCTGCTCCCCCAAAGCAGCACAGCAGTACCAGTCCCTTCCCCACCTCCACGCCCCTCCGCAGAAACTCTATGTCCAGCCATG
GAAAGCAGGGGGCCCCCAAGAAGCGGAAGGCGCCTCCACCTCCCGCCAGCATTCCCATGCCGGATGATCGAGATGCCTATGAGGAGATCG
TGAGGCTGCGGCAGGAGAGGGGCCGCCTCCTGCAGAAGATCCGGGGCCTGGAACAGCACAAGGAACGGAGGCAGCAGGAGTCCCCGGAGG
CCAGCTCCCTGCACATCCTGGAGAGACAGGTGCAAGAGCTACAGCAGTTGCTGGTGGAGAGACAAGAGGAGAAGGAGAGCCTGGGACGGG
AGGTGGAGAGTTTGCAGAGCCGGCTGTCCCTGCTGGAGAACGAGCGGGAGAATACTAGCTATGACGTAACCACCCTGCAGGATGAGGAGG
GTGAGCTGCCTGACCTTCCAGGGGCCGAGGTGCTGCTGTCCAGACAACTCAGTCCGTCGGCCCAGGAACACCTGGCCTCGCTGCAGGAAC
AGGTGGCTGTGCTCACCAGACAGAACCAGGAACTGATGGAGAAGGTCCAGATCCTGGAGAACTTTGAGAAGGACGAGACACAGATGGAAG
TGGAAGCTTTGGCAGAGGTCATCCCTCTTGCCCTCTATGACTCTCTCCGGGCCGAGTTTGACCAGCTACGCAGGCAGCACGCTGAGGCCC
TGCAGGCCCTGAGGCAGCAGGAGACACGAGAGGTCCCCAGAGAAGAGGGGGCAGCCTGTGGGGAGAGTGAGGTTGCTGGAGCCACGGCCA
CCAAAAACGGGCCAACCCACATGGAGCTAAATGGCTCAGTGGCTCCAGAAACCAAAGTTAACGGAGCCGAGACCATAGATGAGGAGGCTG
CAGGAGATGAAACCATGGAAGCCAGGACTATGGAAGCTGAGGCCACGGGAGCCGAGGCCACGGGAGCTGAGGCCACAGGAGCCAAGGTCA
CAGAAACAAAACCCACAGGGGCTGAGGTCAGAGAAATGGAGACCACAGAAGAAGAAGCAAACATGGAAACTAAGCCCACAGGAGCTCAGG
CCACAGACACAGAGACCACGGGAGTGGAGGCCATGGGGGTGGAGGCCACAAAAACAAAAGCAGAGGAAGCAGAAATGCAGGCCTACGGAG
TGGGTGCTGGGCAAGCAGAGCCCCCAGTCACAGGGACCACAAACATGGAGGCCACGGGCTCTAGGGCCACAGGGATGGAATCCACAGGAG
TCAGTGCCACAGGTGTGGAGAACCCAGGGGTAGAGGCCACGGTCCCGGGGATCTCTGCTGGCCCCATCCTACATCCTGGTGCCGCAGAGG
CCTCGGAAAAGCTTCAAGTAGAGCTGGAGACCAGGATCCGTGGCTTGGAGGAGGCTCTCCGGCAGCGGGAGCGGGAGGCAGCTGCGGAGC
TGGAGGCGGCCCTGGGGAAGTGCGAGGCCGCGGAGGCCGAGGCAGGCCGGCTGCGAGAGCGTGTCCGCGAGGCCGAGGGCAGCGGGGCCA
GCGGGGGCGGTGGCGGTGACACCACACAGCTGCGGGCGGCCCTGGAGCAGGCCCGGGAGGACCTCCGAGACCGGGACTCCCGCCTGCGGG
AGCTGGAGGCGGCCTCGGCCTGCCTGGATGAGGCTCGGGCCAGCCGGCTGCTGGCGGAGGAGGAGGCGCGGGGCCTGCGGGCCGAGCTGG
CCCAGCGGGAGGAGGCGCGGCTGGAGCAGAGCCGGGAGCTGGAGGTTCTGCGGGAGCAGCTGGCCACGGCCAGGGCCACGGGGGAGCAGC
AGCGCACGGCGGCCGCGGAACTGGGCCGGGCACGGGACGCCGCTGAGGCCCGAGTGGCTGAGCTGCCTGCGGCCTGCGAGGAGGCGCGGC
AGGGCCTGGCCGAGCTGCGGGAGGCCTCCGAGGCCCTCCGCCAGTCCGTGGTGCCGGCCTCTGAGCACCGCCGGCTGCAGGAGGAGGCCC
TGGAGCTGCGGGGCCGGGCAGCCAGTCTGGAGCAGGAGGTGGTGGCCACGGGCAAGGAGGCCGCCCGGCTGCGCGCGGAGCTGGAGCGGG
AGCGTGTGTGCAGCGTGGCGCTCTCGGAGCACGAACGCATCGTGGGCACCCTGCAGGCCAACGTGGCCCAGCTGGAGGGGCAGCTGGAGG
AGCTGGGACGGCGGCATGAGAAGACCAGCGCAGAGGTCTTCCAGGTGCAGCGTGAGGCCCTGTTCATGAAGAGTGAGCGACACGCAGCCG
AGGCACAGCTGGCCACAGCAGAGCAGCAGCTACGGGGGCTACGGACCGAGGCGGAAAGGGCTCGCCAGGCCCAGAGCCGGGCCCAGGAGG
CTCTGGACAAGGCCAAGGAGAAGGACAAGAAGATCACAGAACTCTCCAAAGAAGTCTTCAATCTTAAGGAAGCCTTGAAGGAGCAGCCGG
CCGCCCTCGCCACCCCTGAGGTGGAGGCTCTCCGTGACCAGGTGAAGGATTTACAGCAGCAGCTGCAGGAAGCTGCCAGGGACCACTCCA
GCGTGGTGGCTTTGTACAGAAGCCACCTCCTATATGCCATTCAGGGCCAGATGGATGAAGATGTGCAGCGGATTCTCAGCCAGATTCTGC
AGATGCAGAGACTCCAGGCTCAGGGCCGCTGAGAAAGGCCAGGCCCAGTGGCTACACTGACCACACCCACGCAGGGACCTCACCCCCCTG
CAGGCCCCTTGCAGACCGGCTTCACTTGGCTTCACTTGGCCCTATCCAGGCCCATGCACTTGGAGACCAGCCTGGTTCCCTGCCCGACCA
CCCCCAGCTGGCTCCATCACCCCACCTGGTCTCTGCACGCACACACTGGTCAGTCTGGACCCGGGCCGTGACTGCCCCTCCCCCACCACC

>16202_16202_2_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000318934_length(amino acids)=1186AA_BP=330
MRGGRAAAGAMLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCH
VGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLA
FPGETLSDIPCKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATP
QGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRNSMSSHGKQGAPKKRKAPPPPASIPMPDDR
DAYEEIVRLRQERGRLLQKIRGLEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVT
TLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLR
RQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAE
ATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRAT
GMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVRE
AEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATA
RATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARL
RAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQA
QSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQR

--------------------------------------------------------------
>16202_16202_3_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000600132_length(transcript)=3941nt_BP=1061nt
GGCGGCAGCAGCGGCGCGGGCGGGAGGGCGAAGAGCAGCGGCCGCCTGAGGGGAGCCCGCGCCTCCGCCGCCTGAGAGGAGGTCGAGCTG
CCGCCGGGGCGATGCTGGAGGAGCTGGAGTGCGGGGCGCCCGGCGCCAGGGGAGCCGCCACAGCCATGGATTGCAAAGATAGACCAGCTT
TTCCAGTTAAGAAGTTAATACAAGCCCGTCTGCCGTTTAAGCGCCTGAATCTTGTCCCAAAGGGGAAAGCCGATGACATGTCAGACGATC
AGGGTACTTCTGTGCAAAGTAAAAGCCCCGATTTAGAGGCCTCTTTGGACACCTTGGAAAACAACTGTCATGTGGGTTCTGACATAGACT
TTAGACCGAAACTTGTCAACGGGAAGGGTCCCTTAGATAACTTTTTAAGAAATAGAATCGAAACCAGTATTGGCCAGAGCACAGTCATCA
TTGATTTGACAGAGGACTCGAATGAGCAGCCAGACAGTCTTGTGGACCACAATAAACTAAATTCTGAAGCCTCTCCCTCCAGGGAGGCAA
TAAATGGCCAGCGAGAAGACACTGGGGATCAGCAGGGGTTGTTGAAGGCCATTCAGAACGACAAGTTGGCATTTCCTGGAGAGACCCTTT
CAGACATTCCTTGCAAAACAGAGGAGGAGGGTGTTGGCTGTGGAGGTGCAGGGAGGAGAGGCGACTCCCAGGAATGTTCGCCACGGAGCT
GCCCGGAGCTGACGAGTGGCCCGAGAATGTGCCCCAGAAAGGAGCAGGACAGTTGGAGTGAAGCTGGGGGCATCCTGTTCAAAGGGAAGG
TGCCTATGGTGGTCTTGCAGGACATCTTGGCTGTGAGACCACCGCAAATCAAGTCCCTTCCAGCCACACCCCAAGGCAAGAACATGACCC
CTGAGAGTGAGGTGCTGGAATCTTTCCCCGAAGAAGACTCTGTACTCAGCCATTCGTCCCTGAGCTCTCCCTCTTCCACCAGCTCGCCCG
AGGGGCCGCCTGCTCCCCCAAAGCAGCACAGCAGTACCAGTCCCTTCCCCACCTCCACGCCCCTCCGCAGAAACTCTATGTCCAGCCATG
GAAAGCAGGGGGCCCCCAAGAAGCGGAAGGCGCCTCCACCTCCCGCCAGCATTCCCATGCCGGATGATCGAGATGCCTATGAGGAGATCG
TGAGGCTGCGGCAGGAGAGGGGCCGCCTCCTGCAGAAGATCCGGGGCCTGGAACAGCACAAGGAACGGAGGCAGCAGGAGTCCCCGGAGG
CCAGCTCCCTGCACATCCTGGAGAGACAGGTGCAAGAGCTACAGCAGTTGCTGGTGGAGAGACAAGAGGAGAAGGAGAGCCTGGGACGGG
AGGTGGAGAGTTTGCAGAGCCGGCTGTCCCTGCTGGAGAACGAGCGGGAGAATACTAGCTATGACGTAACCACCCTGCAGGATGAGGAGG
GTGAGCTGCCTGACCTTCCAGGGGCCGAGGTGCTGCTGTCCAGACAACTCAGTCCGTCGGCCCAGGAACACCTGGCCTCGCTGCAGGAAC
AGGTGGCTGTGCTCACCAGACAGAACCAGGAACTGATGGAGAAGGTCCAGATCCTGGAGAACTTTGAGAAGGACGAGACACAGATGGAAG
TGGAAGCTTTGGCAGAGGTCATCCCTCTTGCCCTCTATGACTCTCTCCGGGCCGAGTTTGACCAGCTACGCAGGCAGCACGCTGAGGCCC
TGCAGGCCCTGAGGCAGCAGGAGACACGAGAGGTCCCCAGAGAAGAGGGGGCAGCCTGTGGGGAGAGTGAGGTTGCTGGAGCCACGGCCA
CCAAAAACGGGCCAACCCACATGGAGCTAAATGGCTCAGTGGCTCCAGAAACCAAAGTTAACGGAGCCGAGACCATAGATGAGGAGGCTG
CAGGAGATGAAACCATGGAAGCCAGGACTATGGAAGCTGAGGCCACGGGAGCCGAGGCCACGGGAGCTGAGGCCACAGGAGCCAAGGTCA
CAGAAACAAAACCCACAGGGGCTGAGGTCAGAGAAATGGAGACCACAGAAGAAGAAGCAAACATGGAAACTAAGCCCACAGGAGCTCAGG
CCACAGACACAGAGACCACGGGAGTGGAGGCCATGGGGGTGGAGGCCACAAAAACAAAAGCAGAGGAAGCAGAAATGCAGGCCTACGGAG
TGGGTGCTGGGCAAGCAGAGCCCCCAGTCACAGGGACCACAAACATGGAGGCCACGGGCTCTAGGGCCACAGGGATGGAATCCACAGGAG
TCAGTGCCACAGGTGTGGAGAACCCAGGGGTAGAGGCCACGGTCCCGGGGATCTCTGCTGGCCCCATCCTACATCCTGGTGCCGCAGAGG
CCTCGGAAAAGCTTCAAGTAGAGCTGGAGACCAGGATCCGTGGCTTGGAGGAGGCTCTCCGGCAGCGGGAGCGGGAGGCAGCTGCGGAGC
TGGAGGCGGCCCTGGGGAAGTGCGAGGCCGCGGAGGCCGAGGCAGGCCGGCTGCGAGAGCGTGTCCGCGAGGCCGAGGGCAGCGGGGCCA
GCGGGGGCGGTGGCGGTGACACCACACAGCTGCGGGCGGCCCTGGAGCAGGCCCGGGAGGACCTCCGAGACCGGGACTCCCGCCTGCGGG
AGCTGGAGGCGGCCTCGGCCTGCCTGGATGAGGCTCGGGCCAGCCGGCTGCTGGCGGAGGAGGAGGCGCGGGGCCTGCGGGCCGAGCTGG
CCCAGCGGGAGGAGGCGCGGCTGGAGCAGAGCCGGGAGCTGGAGGTTCTGCGGGAGCAGCTGGCCACGGCCAGGGCCACGGGGGAGCAGC
AGCGCACGGCGGCCGCGGAACTGGGCCGGGCACGGGACGCCGCTGAGGCCCGAGTGGCTGAGCTGCCTGCGGCCTGCGAGGAGGCGCGGC
AGGGCCTGGCCGAGCTGCGGGAGGCCTCCGAGGCCCTCCGCCAGTCCGTGGTGCCGGCCTCTGAGCACCGCCGGCTGCAGGAGGAGGCCC
TGGAGCTGCGGGGCCGGGCAGCCAGTCTGGAGCAGGAGGTGGTGGCCACGGGCAAGGAGGCCGCCCGGCTGCGCGCGGAGCTGGAGCGGG
AGCGTGTGTGCAGCGTGGCGCTCTCGGAGCACGAACGCATCGTGGGCACCCTGCAGGCCAACGTGGCCCAGCTGGAGGGGCAGCTGGAGG
AGCTGGGACGGCGGCATGAGAAGACCAGCGCAGAGGTCTTCCAGGTGCAGCGTGAGGCCCTGTTCATGAAGAGTGAGCGACACGCAGCCG
AGGCACAGCTGGCCACAGCAGAGCAGCAGCTACGGGGGCTACGGACCGAGGCGGAAAGGGCTCGCCAGGCCCAGAGCCGGGCCCAGGAGG
CTCTGGACAAGGCCAAGGAGAAGGACAAGAAGATCACAGAACTCTCCAAAGAAGTCTTCAATCTTAAGGAAGCCTTGAAGGAGCAGCCGG
CCGCCCTCGCCACCCCTGAGGTGGAGGCTCTCCGTGACCAGGTGAAGGATTTACAGCAGCAGCTGCAGGAAGCTGCCAGGGACCACTCCA
GCGTGGTGGCTTTGTACAGAAGCCACCTCCTATATGCCATTCAGGGCCAGATGGATGAAGATGTGCAGCGGATTCTCAGCCAGATTCTGC
AGATGCAGAGACTCCAGGCTCAGGGCCGCTGAGAAAGGCCAGGCCCAGTGGCTACACTGACCACACCCACGCAGGGACCTCACCCCCCTG
CAGGCCCCTTGCAGACCGGCTTCACTTGGCTTCACTTGGCCCTATCCAGGCCCATGCACTTGGAGACCAGCCTGGTTCCCTGCCCGACCA
CCCCCAGCTGGCTCCATCACCCCACCTGGTCTCTGCACGCACACACTGGTCAGTCTGGACCCGGGCCGTGACTGCCCCTCCCCCACCACC

>16202_16202_3_CHAF1A-ANKRD24_CHAF1A_chr19_4409756_ENST00000301280_ANKRD24_chr19_4210055_ENST00000600132_length(amino acids)=1186AA_BP=330
MRGGRAAAGAMLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTSVQSKSPDLEASLDTLENNCH
VGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLA
FPGETLSDIPCKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATP
QGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRNSMSSHGKQGAPKKRKAPPPPASIPMPDDR
DAYEEIVRLRQERGRLLQKIRGLEQHKERRQQESPEASSLHILERQVQELQQLLVERQEEKESLGREVESLQSRLSLLENERENTSYDVT
TLQDEEGELPDLPGAEVLLSRQLSPSAQEHLASLQEQVAVLTRQNQELMEKVQILENFEKDETQMEVEALAEVIPLALYDSLRAEFDQLR
RQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSVAPETKVNGAETIDEEAAGDETMEARTMEAEATGAEATGAE
ATGAKVTETKPTGAEVREMETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAGQAEPPVTGTTNMEATGSRAT
GMESTGVSATGVENPGVEATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEALRQREREAAAELEAALGKCEAAEAEAGRLRERVRE
AEGSGASGGGGGDTTQLRAALEQAREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVLREQLATA
RATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREASEALRQSVVPASEHRRLQEEALELRGRAASLEQEVVATGKEAARL
RAELERERVCSVALSEHERIVGTLQANVAQLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQA
QSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYRSHLLYAIQGQMDEDVQR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CHAF1A-ANKRD24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CHAF1A-ANKRD24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CHAF1A-ANKRD24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCHAF1AC0026636Mouth Diseases1CTD_human