Fusion Gene Studies
in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BIVM-ERCC5-RBM26 (FusionGDB2 ID:HG100533467TG64062)

Fusion Gene Summary for BIVM-ERCC5-RBM26

check button Fusion gene summary
Fusion gene informationFusion gene name: BIVM-ERCC5-RBM26
Fusion gene ID: hg100533467tg64062
HgeneTgene
Gene symbol

BIVM-ERCC5

RBM26

Gene ID

100533467

64062

Gene nameBIVM-ERCC5 readthroughRNA binding motif protein 26
SynonymsERCC5-202ARRS2|C13orf10|PPP1R132|PRO1777|SE70-2|ZC3H17
Cytomap('BIVM-ERCC5')('RBM26')

13q33.1

13q31.1

Type of geneprotein-codingprotein-coding
DescriptionBIVM-ERCC5 proteinRNA-binding protein 26CTCL tumor antigen se70-2acidic rich RS domain containing 2cutaneous T-cell lymphoma tumor antigen se70-2protein phosphatase 1, regulatory 132
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000602836, 
Fusion gene scores* DoF score3 X 3 X 1=98 X 8 X 2=128
# samples 38
** MAII scorelog2(3/9*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(8/128*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BIVM-ERCC5 [Title/Abstract] AND RBM26 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBIVM-ERCC5(103518629)-RBM26(79940278), # samples:1
Anticipated loss of major functional domain due to fusion event.BIVM-ERCC5-RBM26 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BIVM-ERCC5-RBM26 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRBM26

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across BIVM-ERCC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RBM26 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand


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Fusion Gene ORF analysis for BIVM-ERCC5-RBM26

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000602836ENST00000267229BIVM-ERCC5chr13103518629+RBM26chr1379940278-0.0017791960.99822074
ENST00000602836ENST00000438737BIVM-ERCC5chr13103518629+RBM26chr1379940278-0.0017823540.99821764
ENST00000602836ENST00000438724BIVM-ERCC5chr13103518629+RBM26chr1379940278-0.002004510.9979955

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Fusion Genomic Features for BIVM-ERCC5-RBM26


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for BIVM-ERCC5-RBM26


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:103518629/chr13:79940278)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021719_7950981.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021823_8470981.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021719_7950984.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021823_8470984.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022719_79501008.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022823_84701008.0Coiled coilOntology_term=ECO:0000255
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021134_2130981.0Compositional biasNote=Arg-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021326_4200981.0Compositional biasNote=Pro-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021134_2130984.0Compositional biasNote=Arg-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021326_4200984.0Compositional biasNote=Pro-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022134_21301008.0Compositional biasNote=Arg-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022326_42001008.0Compositional biasNote=Pro-rich
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021532_6060981.0DomainRRM 1
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021891_9600981.0DomainRRM 2
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021532_6060984.0DomainRRM 1
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021891_9600984.0DomainRRM 2
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022532_60601008.0DomainRRM 1
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022891_96001008.0DomainRRM 2
TgeneRBM26chr13:103518629chr13:79940278ENST00000267229021288_3160981.0Zinc fingerC3H1-type
TgeneRBM26chr13:103518629chr13:79940278ENST00000438724021288_3160984.0Zinc fingerC3H1-type
TgeneRBM26chr13:103518629chr13:79940278ENST00000438737022288_31601008.0Zinc fingerC3H1-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for BIVM-ERCC5-RBM26


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9777_9777_1_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000267229_length(transcript)=6000nt_BP=3577nt
ACAAGGTGCTGTAAAATCTTTCTGCACAAGTGCCTCAGGAGCACCCTTGGGTCCCAAAGGAGATGGTCATTATCCATGGAGTTGTCCAGT
GACTCATACACGGGAAAAAATTTATGCCATCTGTTCGGACTATGCCTTTCTCAACCAGGCGACCTCAATCTATAAAACTCCAAATCCATC
CCGCTCTCCTTGCCTCCCTGATAGTACCTCTTTATCTGCTGGAAATAATTCATCAAGATACATTGGTATCCCGACTAGTACATCGGAAAT
TATCTACAATGAAGAAAATAGCTTGGAAAACTTATCCAACAGCCTGGGCAAGCTACCTCTCGCATGGGAAATTGATAAATCTGAATTTGA
TGGGGTGACCACAAATTCGAAACACAAATCAGGCAATGCAAAGAAACAAGTTTCCAAGAGAAAAACTTCAGATAAAAAGGGAAGATATCA
GAAGGAATGTCCTCAGCATTCTCCTCTTGAAGATATTAAACAGCGGAAAGTATTAGACCTCAGACGATGGTACTGCATAAGCCGACCACA
GTATAAGACTTCTTGTGGCATCTCTTCATTAATTTCTTGTTGGAATTTCTTATACAGCACAATGGGAGCTGGAAACCTTCCACCTATTAC
CCAAGAAGAAGCTTTACATATTCTGGGCTTTCAACCTCCATTTGAAGATATTAGGTTTGGTCCTTTCACGGGGAATACAACACTTATGAG
GTGGTTTAGACAAATTAATGACCACTTCCATGTAAAAGGATGCTCTTATGTTCTATATAAGCCTCATGGGAAGAATAAAACAGCAGGAGA
AACTGCTTCAGGGGCCCTGTCAAAGTTAACCCGTGGATTGAAAGATGAATCGCTGGCTTATATCTATCATTGCCAAAATCATTATTTTTG
TCCAATTGGCTTCGAAGCAACCCCTGTTAAAGCTAATAAAGCATTCAGCAGGGGACCTCTCTCACCACAGGAAGTTGAATATTGGATCTT
AATTGGAGAATCAAGTAGAAAACATCCTGCCATTCACTGTAAAAAATGGGCAGATATTGTTACTGATCTAAACACTCAAAATCCAGAATA
CCTGGATATCCGGCACTTAGAGAGGGGACTGCAGTATAGAAAAACAAAGAAGGTTGGGGGAAATTTGCATTGCATCATAGCATTCCAGAG
ACTTAACTGGCAAAGATTTGGCCTTTGGAACTTTCCATTTGGAACCATTAGACAAGAATCACAACCTCCAACACATGCCCAGGGAATTGC
CAAATCTGAGAGTGAAGACAATATTTCCAAGAAGCAGCATGGGCGTCTGGGCCGGTCTTTCAGTGCTAGTTTCCATCAGGACTCGGCATG
GAAAAAGATGTCTAATATTAGCATTTGGTTAAACCAAGCACTTAAAGGAGTCCGGGATCGCCATGGGAACTCAATAGAAAATCCTCATCT
TCTCACTTTGTTTCATCGGCTCTGCAAACTCTTATTTTTTCGAATTCGTCCTATTTTTGTGTTTGATGGGGATGCTCCACTATTGAAGAA
ACAGACTTTGGTGAAGAGAAGGCAGAGAAAGGACTTAGCGTCCAGTGACTCCAGGAAAACGACAGAGAAGCTTCTGAAAACATTTTTGAA
AAGACAAGCCATCAAAACTGCCTTCAGAAGCAAAAGAGATGAAGCACTACCCAGTCTTACCCAAGTTCGAAGAGAAAACGACCTCTATGT
TTTGCCTCCTTTACAAGAGGAAGAAAAACACAGTTCAGAAGAGGAAGATGAAAAAGAATGGCAAGAAAGAATGAATCAAAAACAAGCATT
ACAGGAAGAGTTCTTTCATAATCCTCAAGCGATAGATATTGAGTCTGAGGACTTCAGCAGCCTGCCCCCTGAAGTAAAGCATGAAATCTT
GACTGATATGAAAGAGTTCACCAAGCGCAGAAGAACATTATTTGAAGCAATGCCAGAGGAGTCTGATGACTTTTCACAGTACCAACTCAA
AGGCTTGCTTAAAAAGAACTATCTGAACCAGCATATAGAACATGTCCAAAAGGAAATGAATCAGCAACATTCAGGACACATCCGAAGGCA
GTATGAAGATGAAGGGGGCTTTCTGAAGGAGGTAGAGTCAAGGAGAGTGGTCTCTGAAGACACTTCACATTACATCTTGATAAAAGGTAT
TCAAGCTAAGACAGTTGCAGAAGTGGATTCAGAGTCTCTTCCTTCTTCCAGCAAAATGCACGGCATGTCTTTTGACGTGAAGTCATCTCC
ATGTGAAAAACTGAAGACAGAGAAAGAGCCTGATGCTACCCCTCCTTCTCCAAGAACTTTACTAGCTATGCAAGCTGCCCTGCTGGGAAG
TAGCTCAGAAGAGGAGCTGGAGAGTGAAAATCGAAGGCAGGCCCGTGGGAGGAACGCACCTGCTGCTGTAGACGAAGGCTCCATATCACC
CCGGACTCTTTCAGCCATTAAGAGAGCTCTTGACGATGACGAAGATGTAAAAGTGTGTGCTGGGGATGATGTGCAGACGGGAGGGCCAGG
AGCAGAAGAAATGCGTATAAACAGCTCCACCGAGAACAGTGATGAAGGACTTAAAGTGAGAGATGGAAAAGGAATACCGTTTACTGCAAC
ACTTGCGTCATCTAGTGTGAACTCTGCAGAGGAGCACGTAGCCAGCACTAATGAGGGGAGAGAGCCCACAGACTCAGTTCCAAAAGAACA
AATGTCACTTGTTCACGTGGGGACTGAAGCCTTTCCGATAAGTGATGAGTCTATGATTAAGGACAGAAAAGATCGGCTGCCTCTGGAGAG
TGCAGTGGTTAGACATAGTGACGCACCTGGGCTCCCGAATGGAAGGGAACTGACACCGGCATCTCCAACTTGTACAAATTCTGTGTCAAA
GAATGAAACACATGCTGAAGTGCTTGAGCAGCAGAACGAACTTTGCCCATATGAGAGTAAATTCGATTCTTCTCTTCTTTCAAGTGATGA
TGAAACAAAATGTAAACCGAATTCTGCTTCTGAAGTCATTGGCCCTGTCAGTTTGCAAGAAACAAGTAGCATAGTAAGTGTCCCTTCAGA
GGCAGTAGATAATGTGGAAAATGTGGTGTCATTTAATGCTAAAGAGCATGAGAATTTTCTGGAAACCATCCAAGAACAGCAGACCACTGA
ATCTGCAGGCCAGGATTTAATTTCCATTCCAAAGGCCGTGGAACCAATGGAAATTGACTCGGAAGAAAGTGAATCTGATGGAAGTTTCAT
TGAAGTGCAAAGTGTGATTAGTGATGAGGAACTTCAAGCAGAATTCCCTGAAACTTCCAAACCTCCCTCAGAACAAGGCGAAGAGGAACT
GGTAGGAACTAGGGAGGGAGAAGCCCCTGCTGAGTCCGAGAGCCTCCTGAGGGACAACTCTGAGAGGGACGACGTGGATGGTGAGCCACA
GGAAGCTGAGAAAGATGCGGAAGATTCGCTCCATGAATGGCAAGATATTAATTTGGAGAGCAACCTCTTAGCACAGCAGAATTCACTGAA
AGCTCAAAAACAGCAGCAAGAACGGATCGCTGCTACTGTCACCGGACAGATGTTCCTGGAAAGCCAGTTTCAGGAAGAGTCTTTGGTGGA
TGACTCATTACTTCAAGATGATGATGAAGAAGAAGAGGACAATGAATCTCGTTCTTGGAGAAGATGATTTGACTGATCATTGATCTGCAT
ATGCTAGAACTCTACCTGTGTTTCATTAGTATTATCTAATGTACTTTTACATATTTGTAAAAACAATTTTTGGTAAAATGTGATGAAGAT
GGATTTCACAAATAGACAAAAAAGAAGAAAACTACCTTCTGATCTTGTATTTTGAAAGATTGATGTTTGCATTTTACTTCAGTAAACAAT
TGCTAAAGACATCACACTAGAAACATATGCAATGTTTTTATTACATACTTCTACTGGACATCACAGAATTCTTTGGGTTCTTTGTAATTT
AATGAATAGGTCTGAAAACTTATGACCAATACTTGTTATAACTTAGAGGACTTTGTTTTATTCCAAATAAGGAATGAATTTGCATTTAAA
ATCTTAATGAATGTTTTCAAAACTGAATAGATAACATAGTACTCTAACTAAAGTCTCCAAGTTATGTATTATAATATTACATAGTAGTAT
GCTTAGGCTTTACTATGTATTAGCCTTTTGTTGGACTGTGTATGTATTTTACCATATGGGTTTTAATGATAATGGTGTATGACTGCTTTA
CATGAGTCCTTATGCATCCAGATGTTATAATAAAGTGGAATGGTCTCTTTAAAAAAAAAAAAGGAAAGAAAAGAGAAAAGCAATGACAAA
AAAAAAAAAAAAAAGCTGCAGTTCATGGAGCTCGTTTCAAAGGGCAAGATCTAAAACTGGCATGGAATAAACCAGTAACTAATATTTCAG
CTGTTGAAACAGAAGAAGTTGAGCCTGATGAAGAAGAACAATATGGTGAAATTGAAGATTGTCAGATTGATGATTCCTCACTTCATGCAG
TAATTACATTCAAGACAAGAGCAGAAGCTGAAGCAGCTGCCAAACGAGGGATTCTTTCATCTGGTCGGGGCAGAGGAATTCATTCAAGAG
GTCGAGGTGCAGTTCATGGCCGAGGCAGGGGGCGAGGGCGAGGGCGAGGTGTGCCTGGTCATGCTGTGGTGGATCACCGTCCCAGGGCAT
TGGAGATTTCTGCATTTACGGAGAGCGATAGAGAAGATCTTCTTCCTCATTTTGCGATGCAGAAGGAATTACTTGACACAGAACTGGATT
TATATAAGAAGATGCAGGCTGGAGAAGAAGTCACTGAACTTAGGAGAAAGTATACAGAATTACAGCTGGAAATGTTAATTTCAAAACTGG
AGAAAAACAAAACAATGAAGTCTGAAGATAAAGCAGAAATAATGAAAACTTTAGAGGTTTTGACAAAAAATATTACCAAGTTGAAAGATG
AGGTCAAAGCTGCTTCTCCTGGACGCTGTCTTCCAAAAAGTATAAAAACCAAGACTCAGGAGGCATTGAAACTTCAGCAGGATGTAAGGA
AAAGGAAACAAGAAATTTTAGAAAAGCACATTGAAACACAGAAGGTGTTGTCTACATCTACTGGCCTAACAAAAACAGTGTATAATCCAG
CTGCTTTGAAGGCTGCACAGAAAACCTTACTTGTTTCCACCTCTGCAGTTGATAATAATGAAGCACAGAAAAAAAAACAGCCTTTAGTCC
AGCAGCCCATTTTGCCTGTTGTGAAGCAGTCAGTCAAAGAGCGGCTGGGTCCAGTACCTTCAAGTACTATTGAACCTGCAGAAGCCCAGA
GTGCCTCTTCAGACCTTCCTCAGGTTGCTTATAATGGTGATCCTGAAGGTGCCCTAATCCAATTTGCAACATACGAAGAAGCAAAGAAAG
CAATATCAAGTACGGAAGCAGTATTAAACAATCGCTTTATTAAGGTTTATTGGCACAGAGAAGGAAGCACCCAACAGTTACAAACTACTT
CTCCAAAGACCAAATTTTAATAGAACAAACAGCCCAGGCTTTCAGAAGAAGGTTCAATTTGGAAATGAAAATACCAAGCTTGAACTTAGA
AAAGTTCCTCCAGAATTAAATAATATCAGCAAACTTAATGAACATTTTAGTCGATTTGGAACCTTGGTTAACTTACAGAAAAGCCTCCCA
ATAAAAGCAGTATGAGGATAGTAGTGGACTCAGAATCAAGGAAAAGAACCATTGGTTCTGGAGAGCCTGGAGTTCCTACAAAGAAGACTT
GGTTTGATAAATACATATGACACAGATGGCTACAATCCTGAAGCCCCAAGCATAACAAACACTTCCAGACCTATGTATAGACACAGAGTG
CATGCACAAAGGCCCAACTTGATAGGACTAACATCAGGGGATATGGATTTGCCACCCAGAGAAACTCTGCAACCAGTTCTGTTCCTACTG

>9777_9777_1_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000267229_length(amino acids)=1206AA_BP=
MGPKGDGHYPWSCPVTHTREKIYAICSDYAFLNQATSIYKTPNPSRSPCLPDSTSLSAGNNSSRYIGIPTSTSEIIYNEENSLENLSNSL
GKLPLAWEIDKSEFDGVTTNSKHKSGNAKKQVSKRKTSDKKGRYQKECPQHSPLEDIKQRKVLDLRRWYCISRPQYKTSCGISSLISCWN
FLYSTMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGETASGALSKLTRGLKD
ESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPLSPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKT
KKVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQHGRLGRSFSASFHQDSAWKKMSNISIWLNQALK
GVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEA
LPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFE
AMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPS
SSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDED
VKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISD
ESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGP
VSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEF
PETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLESNLLAQQNSLKAQKQQQERIAATVTG

--------------------------------------------------------------
>9777_9777_2_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000438724_length(transcript)=5955nt_BP=3577nt
ACAAGGTGCTGTAAAATCTTTCTGCACAAGTGCCTCAGGAGCACCCTTGGGTCCCAAAGGAGATGGTCATTATCCATGGAGTTGTCCAGT
GACTCATACACGGGAAAAAATTTATGCCATCTGTTCGGACTATGCCTTTCTCAACCAGGCGACCTCAATCTATAAAACTCCAAATCCATC
CCGCTCTCCTTGCCTCCCTGATAGTACCTCTTTATCTGCTGGAAATAATTCATCAAGATACATTGGTATCCCGACTAGTACATCGGAAAT
TATCTACAATGAAGAAAATAGCTTGGAAAACTTATCCAACAGCCTGGGCAAGCTACCTCTCGCATGGGAAATTGATAAATCTGAATTTGA
TGGGGTGACCACAAATTCGAAACACAAATCAGGCAATGCAAAGAAACAAGTTTCCAAGAGAAAAACTTCAGATAAAAAGGGAAGATATCA
GAAGGAATGTCCTCAGCATTCTCCTCTTGAAGATATTAAACAGCGGAAAGTATTAGACCTCAGACGATGGTACTGCATAAGCCGACCACA
GTATAAGACTTCTTGTGGCATCTCTTCATTAATTTCTTGTTGGAATTTCTTATACAGCACAATGGGAGCTGGAAACCTTCCACCTATTAC
CCAAGAAGAAGCTTTACATATTCTGGGCTTTCAACCTCCATTTGAAGATATTAGGTTTGGTCCTTTCACGGGGAATACAACACTTATGAG
GTGGTTTAGACAAATTAATGACCACTTCCATGTAAAAGGATGCTCTTATGTTCTATATAAGCCTCATGGGAAGAATAAAACAGCAGGAGA
AACTGCTTCAGGGGCCCTGTCAAAGTTAACCCGTGGATTGAAAGATGAATCGCTGGCTTATATCTATCATTGCCAAAATCATTATTTTTG
TCCAATTGGCTTCGAAGCAACCCCTGTTAAAGCTAATAAAGCATTCAGCAGGGGACCTCTCTCACCACAGGAAGTTGAATATTGGATCTT
AATTGGAGAATCAAGTAGAAAACATCCTGCCATTCACTGTAAAAAATGGGCAGATATTGTTACTGATCTAAACACTCAAAATCCAGAATA
CCTGGATATCCGGCACTTAGAGAGGGGACTGCAGTATAGAAAAACAAAGAAGGTTGGGGGAAATTTGCATTGCATCATAGCATTCCAGAG
ACTTAACTGGCAAAGATTTGGCCTTTGGAACTTTCCATTTGGAACCATTAGACAAGAATCACAACCTCCAACACATGCCCAGGGAATTGC
CAAATCTGAGAGTGAAGACAATATTTCCAAGAAGCAGCATGGGCGTCTGGGCCGGTCTTTCAGTGCTAGTTTCCATCAGGACTCGGCATG
GAAAAAGATGTCTAATATTAGCATTTGGTTAAACCAAGCACTTAAAGGAGTCCGGGATCGCCATGGGAACTCAATAGAAAATCCTCATCT
TCTCACTTTGTTTCATCGGCTCTGCAAACTCTTATTTTTTCGAATTCGTCCTATTTTTGTGTTTGATGGGGATGCTCCACTATTGAAGAA
ACAGACTTTGGTGAAGAGAAGGCAGAGAAAGGACTTAGCGTCCAGTGACTCCAGGAAAACGACAGAGAAGCTTCTGAAAACATTTTTGAA
AAGACAAGCCATCAAAACTGCCTTCAGAAGCAAAAGAGATGAAGCACTACCCAGTCTTACCCAAGTTCGAAGAGAAAACGACCTCTATGT
TTTGCCTCCTTTACAAGAGGAAGAAAAACACAGTTCAGAAGAGGAAGATGAAAAAGAATGGCAAGAAAGAATGAATCAAAAACAAGCATT
ACAGGAAGAGTTCTTTCATAATCCTCAAGCGATAGATATTGAGTCTGAGGACTTCAGCAGCCTGCCCCCTGAAGTAAAGCATGAAATCTT
GACTGATATGAAAGAGTTCACCAAGCGCAGAAGAACATTATTTGAAGCAATGCCAGAGGAGTCTGATGACTTTTCACAGTACCAACTCAA
AGGCTTGCTTAAAAAGAACTATCTGAACCAGCATATAGAACATGTCCAAAAGGAAATGAATCAGCAACATTCAGGACACATCCGAAGGCA
GTATGAAGATGAAGGGGGCTTTCTGAAGGAGGTAGAGTCAAGGAGAGTGGTCTCTGAAGACACTTCACATTACATCTTGATAAAAGGTAT
TCAAGCTAAGACAGTTGCAGAAGTGGATTCAGAGTCTCTTCCTTCTTCCAGCAAAATGCACGGCATGTCTTTTGACGTGAAGTCATCTCC
ATGTGAAAAACTGAAGACAGAGAAAGAGCCTGATGCTACCCCTCCTTCTCCAAGAACTTTACTAGCTATGCAAGCTGCCCTGCTGGGAAG
TAGCTCAGAAGAGGAGCTGGAGAGTGAAAATCGAAGGCAGGCCCGTGGGAGGAACGCACCTGCTGCTGTAGACGAAGGCTCCATATCACC
CCGGACTCTTTCAGCCATTAAGAGAGCTCTTGACGATGACGAAGATGTAAAAGTGTGTGCTGGGGATGATGTGCAGACGGGAGGGCCAGG
AGCAGAAGAAATGCGTATAAACAGCTCCACCGAGAACAGTGATGAAGGACTTAAAGTGAGAGATGGAAAAGGAATACCGTTTACTGCAAC
ACTTGCGTCATCTAGTGTGAACTCTGCAGAGGAGCACGTAGCCAGCACTAATGAGGGGAGAGAGCCCACAGACTCAGTTCCAAAAGAACA
AATGTCACTTGTTCACGTGGGGACTGAAGCCTTTCCGATAAGTGATGAGTCTATGATTAAGGACAGAAAAGATCGGCTGCCTCTGGAGAG
TGCAGTGGTTAGACATAGTGACGCACCTGGGCTCCCGAATGGAAGGGAACTGACACCGGCATCTCCAACTTGTACAAATTCTGTGTCAAA
GAATGAAACACATGCTGAAGTGCTTGAGCAGCAGAACGAACTTTGCCCATATGAGAGTAAATTCGATTCTTCTCTTCTTTCAAGTGATGA
TGAAACAAAATGTAAACCGAATTCTGCTTCTGAAGTCATTGGCCCTGTCAGTTTGCAAGAAACAAGTAGCATAGTAAGTGTCCCTTCAGA
GGCAGTAGATAATGTGGAAAATGTGGTGTCATTTAATGCTAAAGAGCATGAGAATTTTCTGGAAACCATCCAAGAACAGCAGACCACTGA
ATCTGCAGGCCAGGATTTAATTTCCATTCCAAAGGCCGTGGAACCAATGGAAATTGACTCGGAAGAAAGTGAATCTGATGGAAGTTTCAT
TGAAGTGCAAAGTGTGATTAGTGATGAGGAACTTCAAGCAGAATTCCCTGAAACTTCCAAACCTCCCTCAGAACAAGGCGAAGAGGAACT
GGTAGGAACTAGGGAGGGAGAAGCCCCTGCTGAGTCCGAGAGCCTCCTGAGGGACAACTCTGAGAGGGACGACGTGGATGGTGAGCCACA
GGAAGCTGAGAAAGATGCGGAAGATTCGCTCCATGAATGGCAAGATATTAATTTGGAGAGCAACCTCTTAGCACAGCAGAATTCACTGAA
AGCTCAAAAACAGCAGCAAGAACGGATCGCTGCTACTGTCACCGGACAGATGTTCCTGGAAAGCCAGTTTCAGGAAGAGTCTTTGGTGGA
TGACTCATTACTTCAAGATGATGATGAAGAAGAAGAGGACAATGAATCTCGTTCTTGGAGAAGATGATTTGACTGATCATTGATCTGCAT
ATGCTAGAACTCTACCTGTGTTTCATTAGTATTATCTAATGTACTTTTACATATTTGTAAAAACAATTTTTGGTAAAATGTGATGAAGAT
GGATTTCACAAATAGACAAAAAAGAAGAAAACTACCTTCTGATCTTGTATTTTGAAAGATTGATGTTTGCATTTTACTTCAGTAAACAAT
TGCTAAAGACATCACACTAGAAACATATGCAATGTTTTTATTACATACTTCTACTGGACATCACAGAATTCTTTGGGTTCTTTGTAATTT
AATGAATAGGTCTGAAAACTTATGACCAATACTTGTTATAACTTAGAGGACTTTGTTTTATTCCAAATAAGGAATGAATTTGCATTTAAA
ATCTTAATGAATGTTTTCAAAACTGAATAGATAACATAGTACTCTAACTAAAGTCTCCAAGTTATGTATTATAATATTACATAGTAGTAT
GCTTAGGCTTTACTATGTATTAGCCTTTTGTTGGACTGTGTATGTATTTTACCATATGGGTTTTAATGATAATGGTGTATGACTGCTTTA
CATGAGTCCTTATGCATCCAGATGTTATAATAAAGTGGAATGGTCTCTTTGCTGCAGTTCATGGAGCTCGTTTCAAAGGGCAAGATCTAA
AACTGGCATGGAATAAACCAGTAACTAATATTTCAGCTGTTGAAACAGAAGAAGTTGAGCCTGATGAAGAAGAACAATATGGTGAAATTG
AAGATTGTCAGATTGATGATTCCTCACTTCATGCAGTAATTACATTCAAGACAAGAGCAGAAGCTGAAGCAGCTGCCAAACGAGGGATTC
TTTCATCTGGTCGGGGCAGAGGAATTCATTCAAGAGGTCGAGGTGCAGTTCATGGCCGAGGCAGGGGGCGAGGGCGAGGGCGAGGTGTGC
CTGGTCATGCTGTGGTGGATCACCGTCCCAGGGCATTGGAGATTTCTGCATTTACGGAGAGCGATAGAGAAGATCTTCTTCCTCATTTTG
CGATGCAGAAGGAATTACTTGACACAGAACTGGATTTATATAAGAAGATGCAGGCTGGAGAAGAAGTCACTGAACTTAGGAGAAAGTATA
CAGAATTACAGCTGGAAATGTTAATTTCAAAACTGGAGAAAAACAAAACAATGAAGTCTGAAGATAAAGCAGAAATAATGAAAACTTTAG
AGGTTTTGACAAAAAATATTACCAAGTTGAAAGATGAGGTCAAAGCTGCTTCTCCTGGACGCTGTCTTCCAAAAAGTATAAAAACCAAGA
CTCAGGAGGCATTGAAACTTCAGCAGGATGTAAGGAAAAGGAAACAAGAAATTTTAGAAAAGCACATTGAAACACAGAAGGTGTTGTCTA
CATCTACTGGCCTAACAAAAACAGTGTATAATCCAGCTGCTTTGAAGGCTGCACAGAAAACCTTACTTGTTTCCACCTCTGCAGTTGATA
ATAATGAAGCACAGAAAAAAAAACAGGTAATGCAGCCTTTAGTCCAGCAGCCCATTTTGCCTGTTGTGAAGCAGTCAGTCAAAGAGCGGC
TGGGTCCAGTACCTTCAAGTACTATTGAACCTGCAGAAGCCCAGAGTGCCTCTTCAGACCTTCCTCAGGTTGCTTATAATGGTGATCCTG
AAGGTGCCCTAATCCAATTTGCAACATACGAAGAAGCAAAGAAAGCAATATCAAGTACGGAAGCAGTATTAAACAATCGCTTTATTAAGG
TTTATTGGCACAGAGAAGGAAGCACCCAACAGTTACAAACTACTTCTCCAAAGACCAAATTTTAATAGAACAAACAGCCCAGGCTTTCAG
AAGAAGGTTCAATTTGGAAATGAAAATACCAAGCTTGAACTTAGAAAAGTTCCTCCAGAATTAAATAATATCAGCAAACTTAATGAACAT
TTTAGTCGATTTGGAACCTTGGTTAACTTACAGAAAAGCCTCCCAATAAAAGCAGTATGAGGATAGTAGTGGACTCAGAATCAAGGAAAA
GAACCATTGGTTCTGGAGAGCCTGGAGTTCCTACAAAGAAGACTTGGTTTGATAAATACATATGACACAGATGGCTACAATCCTGAAGCC
CCAAGCATAACAAACACTTCCAGACCTATGTATAGACACAGAGTGCATGCACAAAGGCCCAACTTGATAGGACTAACATCAGGGGATATG
GATTTGCCACCCAGAGAAACTCTGCAACCAGTTCTGTTCCTACTGTAGTAACAACTGGCATTCATCACCAGCCTCCTCCTGCTCCACCCT

>9777_9777_2_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000438724_length(amino acids)=1206AA_BP=
MGPKGDGHYPWSCPVTHTREKIYAICSDYAFLNQATSIYKTPNPSRSPCLPDSTSLSAGNNSSRYIGIPTSTSEIIYNEENSLENLSNSL
GKLPLAWEIDKSEFDGVTTNSKHKSGNAKKQVSKRKTSDKKGRYQKECPQHSPLEDIKQRKVLDLRRWYCISRPQYKTSCGISSLISCWN
FLYSTMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGETASGALSKLTRGLKD
ESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPLSPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKT
KKVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQHGRLGRSFSASFHQDSAWKKMSNISIWLNQALK
GVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEA
LPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFE
AMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPS
SSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDED
VKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISD
ESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGP
VSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEF
PETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLESNLLAQQNSLKAQKQQQERIAATVTG

--------------------------------------------------------------
>9777_9777_3_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000438737_length(transcript)=6081nt_BP=3577nt
ACAAGGTGCTGTAAAATCTTTCTGCACAAGTGCCTCAGGAGCACCCTTGGGTCCCAAAGGAGATGGTCATTATCCATGGAGTTGTCCAGT
GACTCATACACGGGAAAAAATTTATGCCATCTGTTCGGACTATGCCTTTCTCAACCAGGCGACCTCAATCTATAAAACTCCAAATCCATC
CCGCTCTCCTTGCCTCCCTGATAGTACCTCTTTATCTGCTGGAAATAATTCATCAAGATACATTGGTATCCCGACTAGTACATCGGAAAT
TATCTACAATGAAGAAAATAGCTTGGAAAACTTATCCAACAGCCTGGGCAAGCTACCTCTCGCATGGGAAATTGATAAATCTGAATTTGA
TGGGGTGACCACAAATTCGAAACACAAATCAGGCAATGCAAAGAAACAAGTTTCCAAGAGAAAAACTTCAGATAAAAAGGGAAGATATCA
GAAGGAATGTCCTCAGCATTCTCCTCTTGAAGATATTAAACAGCGGAAAGTATTAGACCTCAGACGATGGTACTGCATAAGCCGACCACA
GTATAAGACTTCTTGTGGCATCTCTTCATTAATTTCTTGTTGGAATTTCTTATACAGCACAATGGGAGCTGGAAACCTTCCACCTATTAC
CCAAGAAGAAGCTTTACATATTCTGGGCTTTCAACCTCCATTTGAAGATATTAGGTTTGGTCCTTTCACGGGGAATACAACACTTATGAG
GTGGTTTAGACAAATTAATGACCACTTCCATGTAAAAGGATGCTCTTATGTTCTATATAAGCCTCATGGGAAGAATAAAACAGCAGGAGA
AACTGCTTCAGGGGCCCTGTCAAAGTTAACCCGTGGATTGAAAGATGAATCGCTGGCTTATATCTATCATTGCCAAAATCATTATTTTTG
TCCAATTGGCTTCGAAGCAACCCCTGTTAAAGCTAATAAAGCATTCAGCAGGGGACCTCTCTCACCACAGGAAGTTGAATATTGGATCTT
AATTGGAGAATCAAGTAGAAAACATCCTGCCATTCACTGTAAAAAATGGGCAGATATTGTTACTGATCTAAACACTCAAAATCCAGAATA
CCTGGATATCCGGCACTTAGAGAGGGGACTGCAGTATAGAAAAACAAAGAAGGTTGGGGGAAATTTGCATTGCATCATAGCATTCCAGAG
ACTTAACTGGCAAAGATTTGGCCTTTGGAACTTTCCATTTGGAACCATTAGACAAGAATCACAACCTCCAACACATGCCCAGGGAATTGC
CAAATCTGAGAGTGAAGACAATATTTCCAAGAAGCAGCATGGGCGTCTGGGCCGGTCTTTCAGTGCTAGTTTCCATCAGGACTCGGCATG
GAAAAAGATGTCTAATATTAGCATTTGGTTAAACCAAGCACTTAAAGGAGTCCGGGATCGCCATGGGAACTCAATAGAAAATCCTCATCT
TCTCACTTTGTTTCATCGGCTCTGCAAACTCTTATTTTTTCGAATTCGTCCTATTTTTGTGTTTGATGGGGATGCTCCACTATTGAAGAA
ACAGACTTTGGTGAAGAGAAGGCAGAGAAAGGACTTAGCGTCCAGTGACTCCAGGAAAACGACAGAGAAGCTTCTGAAAACATTTTTGAA
AAGACAAGCCATCAAAACTGCCTTCAGAAGCAAAAGAGATGAAGCACTACCCAGTCTTACCCAAGTTCGAAGAGAAAACGACCTCTATGT
TTTGCCTCCTTTACAAGAGGAAGAAAAACACAGTTCAGAAGAGGAAGATGAAAAAGAATGGCAAGAAAGAATGAATCAAAAACAAGCATT
ACAGGAAGAGTTCTTTCATAATCCTCAAGCGATAGATATTGAGTCTGAGGACTTCAGCAGCCTGCCCCCTGAAGTAAAGCATGAAATCTT
GACTGATATGAAAGAGTTCACCAAGCGCAGAAGAACATTATTTGAAGCAATGCCAGAGGAGTCTGATGACTTTTCACAGTACCAACTCAA
AGGCTTGCTTAAAAAGAACTATCTGAACCAGCATATAGAACATGTCCAAAAGGAAATGAATCAGCAACATTCAGGACACATCCGAAGGCA
GTATGAAGATGAAGGGGGCTTTCTGAAGGAGGTAGAGTCAAGGAGAGTGGTCTCTGAAGACACTTCACATTACATCTTGATAAAAGGTAT
TCAAGCTAAGACAGTTGCAGAAGTGGATTCAGAGTCTCTTCCTTCTTCCAGCAAAATGCACGGCATGTCTTTTGACGTGAAGTCATCTCC
ATGTGAAAAACTGAAGACAGAGAAAGAGCCTGATGCTACCCCTCCTTCTCCAAGAACTTTACTAGCTATGCAAGCTGCCCTGCTGGGAAG
TAGCTCAGAAGAGGAGCTGGAGAGTGAAAATCGAAGGCAGGCCCGTGGGAGGAACGCACCTGCTGCTGTAGACGAAGGCTCCATATCACC
CCGGACTCTTTCAGCCATTAAGAGAGCTCTTGACGATGACGAAGATGTAAAAGTGTGTGCTGGGGATGATGTGCAGACGGGAGGGCCAGG
AGCAGAAGAAATGCGTATAAACAGCTCCACCGAGAACAGTGATGAAGGACTTAAAGTGAGAGATGGAAAAGGAATACCGTTTACTGCAAC
ACTTGCGTCATCTAGTGTGAACTCTGCAGAGGAGCACGTAGCCAGCACTAATGAGGGGAGAGAGCCCACAGACTCAGTTCCAAAAGAACA
AATGTCACTTGTTCACGTGGGGACTGAAGCCTTTCCGATAAGTGATGAGTCTATGATTAAGGACAGAAAAGATCGGCTGCCTCTGGAGAG
TGCAGTGGTTAGACATAGTGACGCACCTGGGCTCCCGAATGGAAGGGAACTGACACCGGCATCTCCAACTTGTACAAATTCTGTGTCAAA
GAATGAAACACATGCTGAAGTGCTTGAGCAGCAGAACGAACTTTGCCCATATGAGAGTAAATTCGATTCTTCTCTTCTTTCAAGTGATGA
TGAAACAAAATGTAAACCGAATTCTGCTTCTGAAGTCATTGGCCCTGTCAGTTTGCAAGAAACAAGTAGCATAGTAAGTGTCCCTTCAGA
GGCAGTAGATAATGTGGAAAATGTGGTGTCATTTAATGCTAAAGAGCATGAGAATTTTCTGGAAACCATCCAAGAACAGCAGACCACTGA
ATCTGCAGGCCAGGATTTAATTTCCATTCCAAAGGCCGTGGAACCAATGGAAATTGACTCGGAAGAAAGTGAATCTGATGGAAGTTTCAT
TGAAGTGCAAAGTGTGATTAGTGATGAGGAACTTCAAGCAGAATTCCCTGAAACTTCCAAACCTCCCTCAGAACAAGGCGAAGAGGAACT
GGTAGGAACTAGGGAGGGAGAAGCCCCTGCTGAGTCCGAGAGCCTCCTGAGGGACAACTCTGAGAGGGACGACGTGGATGGTGAGCCACA
GGAAGCTGAGAAAGATGCGGAAGATTCGCTCCATGAATGGCAAGATATTAATTTGGAGAGCAACCTCTTAGCACAGCAGAATTCACTGAA
AGCTCAAAAACAGCAGCAAGAACGGATCGCTGCTACTGTCACCGGACAGATGTTCCTGGAAAGCCAGTTTCAGGAAGAGTCTTTGGTGGA
TGACTCATTACTTCAAGATGATGATGAAGAAGAAGAGGACAATGAATCTCGTTCTTGGAGAAGATGATTTGACTGATCATTGATCTGCAT
ATGCTAGAACTCTACCTGTGTTTCATTAGTATTATCTAATGTACTTTTACATATTTGTAAAAACAATTTTTGGTAAAATGTGATGAAGAT
GGATTTCACAAATAGACAAAAAAGAAGAAAACTACCTTCTGATCTTGTATTTTGAAAGATTGATGTTTGCATTTTACTTCAGTAAACAAT
TGCTAAAGACATCACACTAGAAACATATGCAATGTTTTTATTACATACTTCTACTGGACATCACAGAATTCTTTGGGTTCTTTGTAATTT
AATGAATAGGTCTGAAAACTTATGACCAATACTTGTTATAACTTAGAGGACTTTGTTTTATTCCAAATAAGGAATGAATTTGCATTTAAA
ATCTTAATGAATGTTTTCAAAACTGAATAGATAACATAGTACTCTAACTAAAGTCTCCAAGTTATGTATTATAATATTACATAGTAGTAT
GCTTAGGCTTTACTATGTATTAGCCTTTTGTTGGACTGTGTATGTATTTTACCATATGGGTTTTAATGATAATGGTGTATGACTGCTTTA
CATGAGTCCTTATGCATCCAGATGTTATAATAAAGTGGAATGGTCTCTTTAAAAAAAAAAAAGGAAAGAAAAGAGAAAAGCAATGACAAA
AAAAAAAAAAAAAAGCTGCAGTTCATGGAGCTCGTTTCAAAGGGCAAGATCTAAAACTGGCATGGAATAAACCAGTAACTAATATTTCAG
CTGTTGAAACAGAAGAAGTTGAGCCTGATGAAGAAGAACAATATGGTGAAATTGAAGATTGTCAGATTGATGATTCCTCACTTCATGCAG
TAATTACATTCAAGACAAGAGCAGAAGCTGAAGCAGCTGCCAAACGAGGGATTCTTTCATCTGGTCGGGGCAGAGGAATTCATTCAAGAG
GTCGAGGTGCAGTTCATGGCCGAGGCAGGGGGCGAGGGCGAGGGCGAGGTGTGCCTGGTCATGCTGTGGTGGATCACCGTCCCAGGGCAT
TGGAGATTTCTGCATTTACGGAGAGCGATAGAGAAGATCTTCTTCCTCATTTTGCGATGCAGAAGGAATTACTTGACACAGAACTGGATT
TATATAAGAAGATGCAGGCTGGAGAAGAAGTCACTGAACTTAGGAGAAAGTATACAGAATTACAGCTGGAAATGTTAATTTCAAAACTGG
AGAAAAACAAAACAATGAAGTCTGAAGATAAAGCAGAAATAATGAAAACTTTAGAGGTTTTGACAAAAAATATTACCAAGTTGAAAGATG
AGGTCAAAGCTGCTTCTCCTGGACGCTGTCTTCCAAAAAGTATAAAAACCAAGACTCAGGAGGCATTGAAACTTCAGCAGGATGTAAGGA
AAAGGAAACAAGAAATTTTAGAAAAGCACATTGAAACACAGAAGGTGTTGTCTACATCTACTGGCCTAACAAAAACAGTGTATAATCCAG
CTGCTTTGAAGGCTGCACAGAAAACCTTACTTGTTTCCACCTCTGCAGTTGATAATAATGAAGCACAGAAAAAAAAACAGAATGTAACTA
AGTTATCTGTGAAGGACAGGTTGGGTTTTGTATCAAAGCCATCTGTTTCAGCAACTGAAAAGGTAATGCAGCCTTTAGTCCAGCAGCCCA
TTTTGCCTGTTGTGAAGCAGTCAGTCAAAGAGCGGCTGGGTCCAGTACCTTCAAGTACTATTGAACCTGCAGAAGCCCAGAGTGCCTCTT
CAGACCTTCCTCAGGTTGCTTATAATGGTGATCCTGAAGGTGCCCTAATCCAATTTGCAACATACGAAGAAGCAAAGAAAGCAATATCAA
GTACGGAAGCAGTATTAAACAATCGCTTTATTAAGGTTTATTGGCACAGAGAAGGAAGCACCCAACAGTTACAAACTACTTCTCCAAAGA
CCAAATTTTAATAGAACAAACAGCCCAGGCTTTCAGAAGAAGGTTCAATTTGGAAATGAAAATACCAAGCTTGAACTTAGAAAAGTTCCT
CCAGAATTAAATAATATCAGCAAACTTAATGAACATTTTAGTCGATTTGGAACCTTGGTTAACTTACAGAAAAGCCTCCCAATAAAAGCA
GTATGAGGATAGTAGTGGACTCAGAATCAAGGAAAAGAACCATTGGTTCTGGAGAGCCTGGAGTTCCTACAAAGAAGACTTGGTTTGATA
AATACATATGACACAGATGGCTACAATCCTGAAGCCCCAAGCATAACAAACACTTCCAGACCTATGTATAGACACAGAGTGCATGCACAA
AGGCCCAACTTGATAGGACTAACATCAGGGGATATGGATTTGCCACCCAGAGAAACTCTGCAACCAGTTCTGTTCCTACTGTAGTAACAA

>9777_9777_3_BIVM-ERCC5-RBM26_BIVM-ERCC5_chr13_103518629_ENST00000602836_RBM26_chr13_79940278_ENST00000438737_length(amino acids)=1206AA_BP=
MGPKGDGHYPWSCPVTHTREKIYAICSDYAFLNQATSIYKTPNPSRSPCLPDSTSLSAGNNSSRYIGIPTSTSEIIYNEENSLENLSNSL
GKLPLAWEIDKSEFDGVTTNSKHKSGNAKKQVSKRKTSDKKGRYQKECPQHSPLEDIKQRKVLDLRRWYCISRPQYKTSCGISSLISCWN
FLYSTMGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGETASGALSKLTRGLKD
ESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPLSPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKT
KKVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQHGRLGRSFSASFHQDSAWKKMSNISIWLNQALK
GVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEA
LPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFE
AMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPS
SSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDED
VKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISD
ESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGP
VSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEF
PETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLESNLLAQQNSLKAQKQQQERIAATVTG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BIVM-ERCC5-RBM26


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BIVM-ERCC5-RBM26


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BIVM-ERCC5-RBM26


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0003165Anthracosis1CTD_human