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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABCC5-ATP11B (FusionGDB2 ID:HG10057TG23200)

Fusion Gene Summary for ABCC5-ATP11B

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCC5-ATP11B
Fusion gene ID: hg10057tg23200
HgeneTgene
Gene symbol

ABCC5

ATP11B

Gene ID

10057

23200

Gene nameATP binding cassette subfamily C member 5ATPase phospholipid transporting 11B (putative)
SynonymsABC33|EST277145|MOAT-C|MOATC|MRP5|SMRP|pABC11ATPIF|ATPIR
Cytomap('ABCC5')('ATP11B')

3q27.1

3q26.33

Type of geneprotein-codingprotein-coding
Descriptionmultidrug resistance-associated protein 5ATP-binding cassette, sub-family C (CFTR/MRP), member 5canalicular multispecific organic anion transporter Cmulti-specific organic anion transporter Cprobable phospholipid-transporting ATPase IFATPase IRATPase, class VI, type 11BP4-ATPase flippase complex alpha subunit ATP11Btruncated ATPase 11B protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265586, ENST00000334444, 
ENST00000382494, ENST00000392579, 
ENST00000427120, ENST00000446941, 
ENST00000492216, 
Fusion gene scores* DoF score16 X 12 X 9=172812 X 11 X 4=528
# samples 1514
** MAII scorelog2(15/1728*10)=-3.52606881166759
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/528*10)=-1.91511110241349
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCC5 [Title/Abstract] AND ATP11B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCC5(183705558)-ATP11B(182538048), # samples:2
Anticipated loss of major functional domain due to fusion event.ABCC5-ATP11B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCC5-ATP11B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCC5-ATP11B seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ABCC5-ATP11B seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ABCC5-ATP11B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
ABCC5-ATP11B seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABCC5

GO:0042908

xenobiotic transport

10840050

HgeneABCC5

GO:0140115

export across plasma membrane

10840050


check buttonFusion gene breakpoints across ABCC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ATP11B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-56-5898-01AABCC5chr3

183705558

-ATP11Bchr3

182538048

+
ChimerDB4LUSCTCGA-56-5898ABCC5chr3

183705558

-ATP11Bchr3

182538048

+


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Fusion Gene ORF analysis for ABCC5-ATP11B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265586ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
5CDS-intronENST00000334444ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
5CDS-intronENST00000382494ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
5CDS-intronENST00000392579ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000334444ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000334444ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000382494ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000382494ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000392579ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
Frame-shiftENST00000392579ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
In-frameENST00000265586ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
In-frameENST00000265586ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000427120ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000427120ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000446941ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000446941ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000492216ENST00000323116ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-3CDSENST00000492216ENST00000493826ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-intronENST00000427120ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-intronENST00000446941ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+
intron-intronENST00000492216ENST00000482794ABCC5chr3

183705558

-ATP11Bchr3

182538048

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265586ABCC5chr3183705558-ENST00000323116ATP11Bchr3182538048+76416031241091365
ENST00000265586ABCC5chr3183705558-ENST00000493826ATP11Bchr3182538048+1282603121163383

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265586ENST00000323116ABCC5chr3183705558-ATP11Bchr3182538048+5.95E-050.9999405
ENST00000265586ENST00000493826ABCC5chr3183705558-ATP11Bchr3182538048+0.0014118220.99858814

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Fusion Genomic Features for ABCC5-ATP11B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABCC5chr3183705557-ATP11Bchr3182538047+0.0004177210.99958223
ABCC5chr3183705557-ATP11Bchr3182538047+0.0004177210.99958223
ABCC5chr3183705557-ATP11Bchr3182538047+0.0004177210.99958223
ABCC5chr3183705557-ATP11Bchr3182538047+0.0004177210.99958223

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABCC5-ATP11B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:183705558/chr3:182538048)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530179_1991971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57179_199197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56179_199197226.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301021_102591178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301048_106591178.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030105_28991178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301091_117791178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030312_34191178.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030360_87691178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST0000032311603078_8291178.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030899_91091178.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030931_96091178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030983_99791178.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061021_10259196.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061048_10659196.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606105_2899196.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061091_11779196.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606312_3419196.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606360_8769196.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST000004938260678_829196.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606899_9109196.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606931_9609196.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606983_9979196.0Topological domainExtracellular
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301026_104791178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301066_109091178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030290_31191178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030342_35991178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000032311603056_7791178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000032311603083_10491178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030877_89891178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030911_93091178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030961_98291178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000323116030998_102091178.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061026_10479196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061066_10909196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606290_3119196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606342_3599196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST000004938260656_779196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST000004938260683_1049196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606877_8989196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606911_9309196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606961_9829196.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST0000049382606998_10209196.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-5301193_14271971438.0DomainABC transporter 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530179_4591971438.0DomainABC transmembrane type-1 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530562_7831971438.0DomainABC transporter 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530859_11551971438.0DomainABC transmembrane type-1 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-571193_1427197533.3333333333334DomainABC transporter 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57179_459197533.3333333333334DomainABC transmembrane type-1 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57562_783197533.3333333333334DomainABC transporter 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57859_1155197533.3333333333334DomainABC transmembrane type-1 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-561193_1427197226.0DomainABC transporter 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56179_459197226.0DomainABC transmembrane type-1 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56562_783197226.0DomainABC transporter 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56859_1155197226.0DomainABC transmembrane type-1 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-5301227_12341971438.0Nucleotide bindingATP 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530595_6021971438.0Nucleotide bindingATP 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-571227_1234197533.3333333333334Nucleotide bindingATP 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57595_602197533.3333333333334Nucleotide bindingATP 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-561227_1234197226.0Nucleotide bindingATP 2
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56595_602197226.0Nucleotide bindingATP 1
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-5301018_10381971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-5301104_11241971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-5301127_11471971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530219_2391971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530296_3161971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530317_3371971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530400_4201971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530434_4541971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530608_6281971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530848_8681971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530917_9371971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000334444-530997_10171971438.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-571018_1038197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-571104_1124197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-571127_1147197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57219_239197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57296_316197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57317_337197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57400_420197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57434_454197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57608_628197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57848_868197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57917_937197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000382494-57997_1017197533.3333333333334TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-561018_1038197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-561104_1124197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-561127_1147197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56219_239197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56296_316197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56317_337197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56400_420197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56434_454197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56608_628197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56848_868197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56917_937197226.0TransmembraneHelical
HgeneABCC5chr3:183705558chr3:182538048ENST00000392579-56997_1017197226.0TransmembraneHelical
TgeneATP11Bchr3:183705558chr3:182538048ENST000003231160301_5591178.0Topological domainCytoplasmic
TgeneATP11Bchr3:183705558chr3:182538048ENST00000493826061_559196.0Topological domainCytoplasmic


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Fusion Gene Sequence for ABCC5-ATP11B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>294_294_1_ABCC5-ATP11B_ABCC5_chr3_183705558_ENST00000265586_ATP11B_chr3_182538048_ENST00000323116_length(transcript)=7641nt_BP=603nt
CACTCAGAGAAGATGAAGGATATCGACATAGGAAAAGAGTATATCATCCCCAGTCCTGGGTATAGAAGTGTGAGGGAGAGAACCAGCACT
TCTGGGACGCACAGAGACCGTGAAGATTCCAAGTTCAGGAGAACTCGACCGTTGGAATGCCAAGATGCCTTGGAAACAGCAGCCCGAGCC
GAGGGCCTCTCTCTTGATGCCTCCATGCATTCTCAGCTCAGAATCCTGGATGAGGAGCATCCCAAGGGAAAGTACCATCATGGCTTGAGT
GCTCTGAAGCCCATCCGGACTACTTCCAAACACCAGCACCCAGTGGACAATGCTGGGCTTTTTTCCTGTATGACTTTTTCGTGGCTTTCT
TCTCTGGCCCGTGTGGCCCACAAGAAGGGGGAGCTCTCAATGGAAGACGTGTGGTCTCTGTCCAAGCACGAGTCTTCTGACGTGAACTGC
AGAAGACTAGAGAGACTGTGGCAAGAAGAGCTGAATGAAGTTGGGCCAGACGCTGCTTCCCTGCGAAGGGTTGTGTGGATCTTCTGCCGC
ACCAGGCTCATCCTGTCCATCGTGTGCCTGATGATCACGCAGCTGGCTGGCTTCAGTGGACCAGGTTTTGACCCACCACATCAGAGTGAC
ACAAGAACCATCTACGTAGCCAACAGGTTTCCTCAGAATGGCCTTTACACACCTCAGAAATTTATAGATAACAGGATCATTTCATCTAAG
TACACTGTGTGGAATTTTGTTCCAAAAAATTTATTTGAACAGTTCAGAAGAGTGGCAAACTTTTATTTTCTTATTATATTTTTGGTTCAG
CTTATGATTGATACACCTACCAGTCCAGTTACCAGTGGACTTCCATTATTCTTTGTGATAACAGTAACTGCCATAAAGCAGGGATATGAA
GATTGGTTACGGCATAACTCAGATAATGAAGTAAATGGAGCTCCTGTTTATGTTGTTCGAAGTGGTGGCCTTGTAAAAACTAGATCAAAA
AACATTCGGGTGGGTGATATTGTTCGAATAGCCAAAGATGAAATTTTTCCTGCAGACTTGGTGCTTCTGTCCTCAGATCGACTGGATGGT
TCCTGTCACGTTACAACTGCTAGTTTGGACGGAGAAACTAACCTGAAGACACATGTGGCAGTTCCAGAAACAGCATTATTACAAACAGTT
GCCAATTTGGACACTCTAGTAGCTGTAATAGAATGCCAGCAACCAGAAGCAGACTTATACAGATTCATGGGACGAATGATCATAACCCAA
CAAATGGAAGAAATTGTAAGACCTCTGGGGCCGGAGAGTCTCCTGCTTCGTGGAGCCAGATTAAAAAACACAAAAGAAATTTTTGGTGTT
GCGGTATACACTGGAATGGAAACTAAGATGGCATTAAATTACAAGAGCAAATCACAGAAACGATCTGCAGTAGAAAAGTCAATGAATACA
TTTTTGATAATTTATCTAGTAATTCTTATATCTGAAGCTGTCATCAGCACTATCTTGAAGTATACATGGCAAGCTGAAGAAAAATGGGAT
GAACCTTGGTATAACCAAAAAACAGAACATCAAAGAAATAGCAGTAAGATTCTGAGATTTATTTCAGACTTCCTTGCTTTTTTGGTTCTC
TACAATTTCATCATTCCAATTTCATTATATGTGACAGTCGAAATGCAGAAATTTCTTGGATCATTTTTTATTGGCTGGGATCTTGATCTG
TATCATGAAGAATCAGATCAGAAAGCTCAAGTCAATACTTCCGATCTGAATGAAGAGCTTGGACAGGTAGAGTACGTGTTTACAGATAAA
ACTGGTACACTGACAGAAAATGAGATGCAGTTTCGGGAATGTTCAATTAATGGCATGAAATACCAAGAAATTAATGGTAGACTTGTACCC
GAAGGACCAACACCAGACTCTTCAGAAGGAAACTTATCTTATCTTAGTAGTTTATCCCATCTTAACAACTTATCCCATCTTACAACCAGT
TCCTCTTTCAGAACCAGTCCTGAAAATGAAACTGAACTAATTAAAGAACATGATCTCTTCTTTAAAGCAGTCAGTCTCTGTCACACTGTA
CAGATTAGCAATGTTCAAACTGACTGCACTGGTGATGGTCCCTGGCAATCCAACCTGGCACCATCGCAGTTGGAGTACTATGCATCTTCA
CCAGATGAAAAGGCTCTAGTAGAAGCTGCTGCAAGGATTGGTATTGTGTTTATTGGCAATTCTGAAGAAACTATGGAGGTTAAAACTCTT
GGAAAACTGGAACGGTACAAACTGCTTCATATTCTGGAATTTGATTCAGATCGTAGGAGAATGAGTGTAATTGTTCAGGCACCTTCAGGT
GAGAAGTTATTATTTGCTAAAGGAGCTGAGTCATCAATTCTCCCTAAATGTATAGGTGGAGAAATAGAAAAAACCAGAATTCATGTAGAT
GAATTTGCTTTGAAAGGGCTAAGAACTCTGTGTATAGCATATAGAAAATTTACATCAAAAGAGTATGAGGAAATAGATAAACGCATATTT
GAAGCCAGGACTGCCTTGCAGCAGCGGGAAGAGAAATTGGCAGCTGTTTTCCAGTTCATAGAGAAAGACCTGATATTACTTGGAGCCACA
GCAGTAGAAGACAGACTACAAGATAAAGTTCGAGAAACTATTGAAGCATTGAGAATGGCTGGTATCAAAGTATGGGTACTTACTGGGGAT
AAACATGAAACAGCTGTTAGTGTGAGTTTATCATGTGGCCATTTTCATAGAACCATGAACATCCTTGAACTTATAAACCAGAAATCAGAC
AGCGAGTGTGCTGAACAATTGAGGCAGCTTGCCAGAAGAATTACAGAGGATCATGTGATTCAGCATGGGCTGGTAGTGGATGGGACCAGC
CTATCTCTTGCACTCAGGGAGCATGAAAAACTATTTATGGAAGTTTGCAGAAATTGTTCAGCTGTATTATGCTGTCGTATGGCTCCACTG
CAGAAAGCAAAAGTAATAAGACTAATAAAAATATCACCTGAGAAACCTATAACATTGGCTGTTGGTGATGGTGCTAATGACGTAAGCATG
ATACAAGAAGCCCATGTTGGCATAGGAATCATGGGTAAAGAAGGAAGACAGGCTGCAAGAAACAGTGACTATGCAATAGCCAGATTTAAG
TTCCTCTCCAAATTGCTTTTTGTTCATGGTCATTTTTATTATATTAGAATAGCTACCCTTGTACAGTATTTTTTTTATAAGAATGTGTGC
TTTATCACACCCCAGTTTTTATATCAGTTCTACTGTTTGTTTTCTCAGCAAACATTGTATGACAGCGTGTACCTGACTTTATACAATATT
TGTTTTACTTCCCTACCTATTCTGATATATAGTCTTTTGGAACAGCATGTAGACCCTCATGTGTTACAAAATAAGCCCACCCTTTATCGA
GACATTAGTAAAAACCGCCTCTTAAGTATTAAAACATTTCTTTATTGGACCATCCTGGGCTTCAGTCATGCCTTTATTTTCTTTTTTGGA
TCCTATTTACTAATAGGGAAAGATACATCTCTGCTTGGAAATGGCCAGATGTTTGGAAACTGGACATTTGGCACTTTGGTCTTCACAGTC
ATGGTTATTACAGTCACAGTAAAGATGGCTCTGGAAACTCATTTTTGGACTTGGATCAACCATCTCGTTACCTGGGGATCTATTATATTT
TATTTTGTATTTTCCTTGTTTTATGGAGGGATTCTCTGGCCATTTTTGGGCTCCCAGAATATGTATTTTGTGTTTATTCAGCTCCTGTCA
AGTGGTTCTGCTTGGTTTGCCATAATCCTCATGGTTGTTACATGTCTATTTCTTGATATCATAAAGAAGGTCTTTGACCGACACCTCCAC
CCTACAAGTACTGAAAAGGCACAGCTTACTGAAACAAATGCAGGTATCAAGTGCTTGGACTCCATGTGCTGTTTCCCGGAAGGAGAAGCA
GCGTGTGCATCTGTTGGAAGAATGCTGGAACGAGTTATAGGAAGATGTAGTCCAACCCACATCAGCAGATCATGGAGTGCATCGGATCCT
TTCTATACCAACGACAGGAGCATCTTGACTCTCTCCACAATGGACTCATCTACTTGTTAAAGGGGCAGTAGTACTTTGTGGGAGCCAGTT
CACCTCCTTTCCTAAAATTCAGTGTGATCACCCTGTTAATGGCCACACTAGCTCTGAAATTAATTTCCAAAATCTTTGTAGTAGTTCATA
CCCACTCAGAGTTATAATGGCAAACAAACAGAAAGCATTAGTACAAGCCCCTCCCAACACCCTTAATTTGAATCTGAACATGTTAAAATT
TGAGAATAAAGAGACATTTTTCATCTCTTTGTCTGGTTTGTCCCTTGTGCTTATGGGACTCCTAATGGCATTTCAGTCTGTTGCTGAGGC
CATTATATTTTAATATAAATGTAGAAAAAAGAGAGAAATCTTAGTAAAGAGTATTTTTTAGTATTAGCTTGATTATTGACTCTTCTATTT
AAATCTGCTTCTGTAAATTATGCTGAAAGTTTGCCTTGAGAACTCTATTTTTTTATTAGAGTTATATTTAAAGCTTTTCATGGGAAAAGT
TAATGTGAATACTGAGGAATTTTGGTCCCTCAGTGACCTGTGTTGTTAATTCATTAATGCATTCTGAGTTCACAGAGCAAATTAGGAGAA
TCATTTCCAACCATTATTTACTGCAGTATGGGGAGTAAATTTATACCAATTCCTCTAACTGTACTGTAACACAGCCTGTAAAGTTAGCCA
TATAAATGCAAGGGTATATCATATATACAAATCAGGAATCAGGTCCGTTCACCGAACTTCAAATTGATGTTTACTAATATTTTTGTGACA
GAGTATAAAGACCCTATAGTGGGTAAATTAGATACTATTAGCATATTATTAATTTAATGTCTTTATCATTGGATCTTTTGCATGCTTTAA
TCTGGTTAACATATTTAAATTTGCTTTTTTTCTCTTTACCTGAAGGCTCTGTGTATAGTATTTCATGACATCGTTGTACAGTTTAACTAT
ATCAATAAAAAGTTTGGACAGTATTTAAATATTGCAAATATGTTTAATTATACAAATCAGAATAGTATGGGTAATTAAATGAATACAAAA
AGAAGAGCCTCTTTCTGCAGCCGACTTAGACATGCTCTTCCCTTTCTATAAGCTAGATTTTAGAATAAAGGGTTTCAGTTAATAATCTTA
TTTTCAGGTTATGTCATCTAACTTATAGCAAACTACCACAATACAGTGAGTTCTGCCAGTGTCCCAGTACAAGGCATATTTCAGGTGTGG
CTGTGGAATGTAAAAATGCTCAACTTGTATCAGGTAATGTTAGCAATAAATTAAATGCTAAGAATGATTAATCGGGTACATGTTACTGTA
ATTAACTCATTGCACTTCAAAACCTAACTTCCATCCTGAATTTATCAAGTAGTTCAGTATTGTCATTTGTTTTTGTTTTATTGAAAAGTA
ATGTTGTCTTAAGATTTAGAAGTGATTATTAGCTTGAGAACTATTACCCAGCTCTAAGCAAATAATGATTGTATACATATTAAGATAATG
GTTAAATGCGGTTTTACCAAGTTTTCCCTTGAAAATGTAATTCCTTTATGGAGATTTATTGTGCAGCCCTAAGCTTCCTTCCCATTTCAT
GAATATAAGGCTTCTAGAATTGGACTGGCAGGGGAAAGAATGGTAGAGACAGAAATTAAGACTTTATCCTTGTTTGCTTGTAAACTATTA
TTTTCTTGCTAATGTAACATTTGTCTGTTCCAGTGATGTAAGGATATTAAGTTATTAAGCTAAATATTAATTTTCAAAAATAGTCCTTCT
TTAACTTAGATATTTCATAGCTGGATTTAGGAAGATCTGTTATTCTGGAAGTACTAAAAAGAATAATACAACGTACAATGTCTGCATTCA
CTAATTCATGTTCCAGAAGAGGAAATAATGAAGATATACTCAGTAGAGTACTAGGTGGGAGGATATGGAAATTTGCTCATAAAATCTCTT
ATAAAACGTGCATATAACAAAATGACACCCAGTAGGCCTGCATTACATTTACATGACCGTGTTTATTTGCCATCAAATAAACTGAGTACT
GACACCAGACAAAGACTCCAAAGTCATAAAATAGCCTATGACCAACTGCAGCAAGACAGGAGGTCAGCTCGCCTATAATGGTGCTTAAAG
TGTGATTGATGTAATTTTCTGTACTCACCATTTGAAGTTAGTTAAGGAGAACTTTATTTTTTTAAAAAAAGTAAATGGCAACCACTAGTG
TGCTCATCCTGAACTGTTACTCCAAATCCACTCCGTTTTTAAAGCAAAATTATCTTGTGATTTTAAGAAAAGAGTTTTCTATTTATTTAA
GAAAGTAACAATGCAGTCTGCAAGCTTTCAGTAGTTTTCTAGTGCTATATTCATCCTGTAAAACTCTTACTACGTAACCAGTAATCACAA
GGAAAGTGTCCCCTTTGCATATTTCTTTAAAATTCTTTCTTTGGAAAGTATGATGTTGATAATTAACTTACCCTTATCTGCCAAAACCAG
AGCAAAATGCTAAATACGTTATTGCTAATCAGTGGTCTCAAATCGATTTGCCTCCCTTTGCCTCGTCTGAGGGCTGTAAGCCTGAAGATA
GTGGCAAGCACCAAGTCAGTTTCCAAAATTGCCCCTCAGCTGCTTTAAGTGACTCAGCACCCTGCCTCAGCTTCAGCAGGCGTAGGCTCA
CCCTGGGCGGAGCAAAGTATGGGCCAGGGAGAACTACAGCTACGAAGACCTGCTGTCGAGTTGAGAAAAGGGGAGAATTTATGGTCTGAA
TTTTCTAACTGTCCTCTTTCTTGGGTCTAAAGCTCATAATACACAAAGGCTTCCAGACCTGAGCCACACCCAGGCCCTATCCTGAACAGG
AGACTAAACAGAGGCAAATCAACCCTAGGAAATACTTGCATTCTGCCCTACGGTTAGTACCAGGACTGAGGTCATTTCTACTGGAAAAGA
TTGTGAGATTGAACTTATCTGATCGCTTGAGACTCCTAATAGGCAGGAGTCAAGGCCACTAGAAAATTGACAGTTAAGAGCCAAAAGTTT
TTAAAATATGCTACTCTGAAAAATCTCGTGAAGGCTGTAGGAAAAGGGAGAATCTTCCATGTTGGTGTTTTTCCTGTAAAGATCAGTTTG
GGGTATGATATAAGCAGGTATTAATAAAAATAACACACCAAAGAGTTACGTAAAACATGTTTTATTAATTTTGGTCCCCACGTACAGACA
TTTTATTTCTATTTTGAAATGAGTTATCTATTTTCATAAAAGTAAAACACTATTAAAGTGCTGTTTTATGTGAAATAACTTGAATGTTGT
TCCTATAAAAAATAGATCATAACTCATGATATGTTTGTAATCATGGTAATTTAGATTTTTATGAGGAATGAGTATCTGGAAATATTGTAG
CAATACTTGGTTTAAAATTTTGGACCTGAGACACTGTGGCTGTCTAATGTAATCCTTTAAAAATTCTCTGCATTGTCAGTAAATGTAGTA

>294_294_1_ABCC5-ATP11B_ABCC5_chr3_183705558_ENST00000265586_ATP11B_chr3_182538048_ENST00000323116_length(amino acids)=1365AA_BP=192
MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDALETAARAEGLSLDASMHSQLRILDEEHPKGKYHHGLSALKP
IRTTSKHQHPVDNAGLFSCMTFSWLSSLARVAHKKGELSMEDVWSLSKHESSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLI
LSIVCLMITQLAGFSGPGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMID
TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHV
TTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYT
GMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFI
IPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPT
PDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEK
ALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIEKTRIHVDEFAL
KGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHET
AVSVSLSCGHFHRTMNILELINQKSDSECAEQLRQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAK
VIRLIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITP
QFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLL
IGKDTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSA
WFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQLTETNAGIKCLDSMCCFPEGEAACASVGRMLERVIGRCSPTHISRSWSASDPFYTN

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>294_294_2_ABCC5-ATP11B_ABCC5_chr3_183705558_ENST00000265586_ATP11B_chr3_182538048_ENST00000493826_length(transcript)=1282nt_BP=603nt
CACTCAGAGAAGATGAAGGATATCGACATAGGAAAAGAGTATATCATCCCCAGTCCTGGGTATAGAAGTGTGAGGGAGAGAACCAGCACT
TCTGGGACGCACAGAGACCGTGAAGATTCCAAGTTCAGGAGAACTCGACCGTTGGAATGCCAAGATGCCTTGGAAACAGCAGCCCGAGCC
GAGGGCCTCTCTCTTGATGCCTCCATGCATTCTCAGCTCAGAATCCTGGATGAGGAGCATCCCAAGGGAAAGTACCATCATGGCTTGAGT
GCTCTGAAGCCCATCCGGACTACTTCCAAACACCAGCACCCAGTGGACAATGCTGGGCTTTTTTCCTGTATGACTTTTTCGTGGCTTTCT
TCTCTGGCCCGTGTGGCCCACAAGAAGGGGGAGCTCTCAATGGAAGACGTGTGGTCTCTGTCCAAGCACGAGTCTTCTGACGTGAACTGC
AGAAGACTAGAGAGACTGTGGCAAGAAGAGCTGAATGAAGTTGGGCCAGACGCTGCTTCCCTGCGAAGGGTTGTGTGGATCTTCTGCCGC
ACCAGGCTCATCCTGTCCATCGTGTGCCTGATGATCACGCAGCTGGCTGGCTTCAGTGGACCAGGTTTTGACCCACCACATCAGAGTGAC
ACAAGAACCATCTACGTAGCCAACAGGTTTCCTCAGAATGGCCTTTACACACCTCAGAAATTTATAGATAACAGGATCATTTCATCTAAG
TACACTGTGTGGAATTTTGTTCCAAAAAATTTATTTGAACAGTTCAGAAGAGTGGCAAACTTTTATTTTCTTATTATATTTTTGGTTCAG
CTTATGATTGATACACCTACCAGTCCAGTTACCAGTGGACTTCCATTATTCTTTGTGATAACAGTAACTGCCATAAAGCAGGGATATGAA
GATTGGTTACGGCATAACTCAGATAATGAAGTAAATGGAGCTCCTGTTTATGTTGTTCGAAGTGGTGGCCTTGTAAAAACTAGATCAAAA
AACATTCGGGTGGGTGATATTGTTCGAATAGCCAAAGATGAAATTTTTCCTGCAGACTTGGTGCTTCTGTCCTCAGATCGACTGGATGGT
TCCTGTCACGTTACAACTGCTAGTTTGGACGGAGAAACTAACCTGAAGGTTTGCTTGCATATGTTTGAGTATTGCTCTTGGTGAACAAAG
TGTCTTTGGATTATAATTATACTTAACTTTGGTTAAAGTAGTAAAGTTTGACCAGATTAAGGGGAAGTTTTTAAAATTACTATTTCAAAA

>294_294_2_ABCC5-ATP11B_ABCC5_chr3_183705558_ENST00000265586_ATP11B_chr3_182538048_ENST00000493826_length(amino acids)=383AA_BP=192
MKDIDIGKEYIIPSPGYRSVRERTSTSGTHRDREDSKFRRTRPLECQDALETAARAEGLSLDASMHSQLRILDEEHPKGKYHHGLSALKP
IRTTSKHQHPVDNAGLFSCMTFSWLSSLARVAHKKGELSMEDVWSLSKHESSDVNCRRLERLWQEELNEVGPDAASLRRVVWIFCRTRLI
LSIVCLMITQLAGFSGPGFDPPHQSDTRTIYVANRFPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMID
TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHV

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Fusion Gene PPI Analysis for ABCC5-ATP11B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCC5-ATP11B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCC5-ATP11B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCC5C0003873Rheumatoid Arthritis1CTD_human
HgeneABCC5C0009402Colorectal Carcinoma1CTD_human
HgeneABCC5C0009404Colorectal Neoplasms1CTD_human
HgeneABCC5C0023893Liver Cirrhosis, Experimental1CTD_human