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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACTR2-UGP2 (FusionGDB2 ID:HG10097TG7360)

Fusion Gene Summary for ACTR2-UGP2

check button Fusion gene summary
Fusion gene informationFusion gene name: ACTR2-UGP2
Fusion gene ID: hg10097tg7360
HgeneTgene
Gene symbol

ACTR2

UGP2

Gene ID

10097

7360

Gene nameactin related protein 2UDP-glucose pyrophosphorylase 2
SynonymsARP2EIEE83|SVUGP2|UDPG|UDPGP|UDPGP2|UGP1|UGPP1|UGPP2|pHC379
Cytomap('ACTR2')('UGP2')

2p14

2p15

Type of geneprotein-codingprotein-coding
Descriptionactin-related protein 2ARP2 actin related protein 2 homologactin-like protein 2UTP--glucose-1-phosphate uridylyltransferaseUDP-glucose diphosphorylaseUDP-glucose pyrophosphorylase 1UGPase 2UTP--glucose-1-phosphate uridylyltransferase 2UTP-glucose-1-phosphate uridyltransferaseUridyl diphosphate glucose pyrophosphorylase-1testi
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000260641, ENST00000377982, 
ENST00000542850, ENST00000476840, 
Fusion gene scores* DoF score8 X 8 X 5=32010 X 7 X 5=350
# samples 910
** MAII scorelog2(9/320*10)=-1.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/350*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACTR2 [Title/Abstract] AND UGP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACTR2(65492309)-UGP2(64109599), # samples:1
ACTR2(65492309)-UGP2(64109600), # samples:1
Anticipated loss of major functional domain due to fusion event.ACTR2-UGP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTR2-UGP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACTR2

GO:0034314

Arp2/3 complex-mediated actin nucleation

11741539|17220302|29925947

HgeneACTR2

GO:0045944

positive regulation of transcription by RNA polymerase II

17220302

HgeneACTR2

GO:1905168

positive regulation of double-strand break repair via homologous recombination

29925947

HgeneACTR2

GO:2001032

regulation of double-strand break repair via nonhomologous end joining

29925947


check buttonFusion gene breakpoints across ACTR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across UGP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BR-6802-11AACTR2chr2

65492309

+UGP2chr2

64109599

+
ChimerDB4Non-CancerTCGA-BR-6802-11AACTR2chr2

65492309

+UGP2chr2

64109600

+


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Fusion Gene ORF analysis for ACTR2-UGP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000260641ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000260641ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000260641ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000260641ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000260641ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000260641ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000377982ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000377982ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000377982ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000377982ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000377982ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000377982ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000542850ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000542850ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000542850ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000542850ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109600

+
5CDS-3UTRENST00000542850ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109599

+
5CDS-3UTRENST00000542850ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000260641ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000260641ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000260641ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000260641ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000377982ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000377982ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000377982ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000377982ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000542850ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000542850ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109600

+
In-frameENST00000542850ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109599

+
In-frameENST00000542850ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109600

+
intron-3CDSENST00000476840ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109599

+
intron-3CDSENST00000476840ENST00000394417ACTR2chr2

65492309

+UGP2chr2

64109600

+
intron-3CDSENST00000476840ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109599

+
intron-3CDSENST00000476840ENST00000467648ACTR2chr2

65492309

+UGP2chr2

64109600

+
intron-3UTRENST00000476840ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109599

+
intron-3UTRENST00000476840ENST00000337130ACTR2chr2

65492309

+UGP2chr2

64109600

+
intron-3UTRENST00000476840ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109599

+
intron-3UTRENST00000476840ENST00000445915ACTR2chr2

65492309

+UGP2chr2

64109600

+
intron-3UTRENST00000476840ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109599

+
intron-3UTRENST00000476840ENST00000487469ACTR2chr2

65492309

+UGP2chr2

64109600

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000260641ACTR2chr265492309+ENST00000394417UGP2chr264109599+277811711302442770
ENST00000260641ACTR2chr265492309+ENST00000467648UGP2chr264109599+266711711302442770
ENST00000542850ACTR2chr265492309+ENST00000394417UGP2chr264109599+2880127313062544412
ENST00000542850ACTR2chr265492309+ENST00000467648UGP2chr264109599+2769127313062544412
ENST00000377982ACTR2chr265492309+ENST00000394417UGP2chr264109599+27091102462373775
ENST00000377982ACTR2chr265492309+ENST00000467648UGP2chr264109599+25981102462373775
ENST00000260641ACTR2chr265492309+ENST00000394417UGP2chr264109600+277811711302442770
ENST00000260641ACTR2chr265492309+ENST00000467648UGP2chr264109600+266711711302442770
ENST00000542850ACTR2chr265492309+ENST00000394417UGP2chr264109600+2880127313062544412
ENST00000542850ACTR2chr265492309+ENST00000467648UGP2chr264109600+2769127313062544412
ENST00000377982ACTR2chr265492309+ENST00000394417UGP2chr264109600+27091102462373775
ENST00000377982ACTR2chr265492309+ENST00000467648UGP2chr264109600+25981102462373775

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260641ENST00000394417ACTR2chr265492309+UGP2chr264109599+0.000140750.9998592
ENST00000260641ENST00000467648ACTR2chr265492309+UGP2chr264109599+0.0001469280.999853
ENST00000542850ENST00000394417ACTR2chr265492309+UGP2chr264109599+0.0002174050.9997826
ENST00000542850ENST00000467648ACTR2chr265492309+UGP2chr264109599+0.0002277040.99977225
ENST00000377982ENST00000394417ACTR2chr265492309+UGP2chr264109599+0.0004187780.9995813
ENST00000377982ENST00000467648ACTR2chr265492309+UGP2chr264109599+0.0004383290.9995616
ENST00000260641ENST00000394417ACTR2chr265492309+UGP2chr264109600+0.000140750.9998592
ENST00000260641ENST00000467648ACTR2chr265492309+UGP2chr264109600+0.0001469280.999853
ENST00000542850ENST00000394417ACTR2chr265492309+UGP2chr264109600+0.0002174050.9997826
ENST00000542850ENST00000467648ACTR2chr265492309+UGP2chr264109600+0.0002277040.99977225
ENST00000377982ENST00000394417ACTR2chr265492309+UGP2chr264109600+0.0004187780.9995813
ENST00000377982ENST00000467648ACTR2chr265492309+UGP2chr264109600+0.0004383290.9995616

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Fusion Genomic Features for ACTR2-UGP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ACTR2chr265492309+UGP2chr264109599+0.0001500770.9998499
ACTR2chr265492309+UGP2chr264109599+0.0001500770.9998499

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ACTR2-UGP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:65492309/chr2:64109599)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTR2chr2:65492309chr2:64109599ENST00000260641+89160_162338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109599ENST00000260641+89214_218338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109599ENST00000260641+89305_310338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109599ENST00000377982+910160_162343400.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109599ENST00000377982+910214_218343400.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109599ENST00000377982+910305_310343400.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000260641+89160_162338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000260641+89214_218338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000260641+89305_310338395.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000377982+910160_162343400.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000377982+910214_218343400.0Nucleotide bindingATP
HgeneACTR2chr2:65492309chr2:64109600ENST00000377982+910305_310343400.0Nucleotide bindingATP
TgeneUGP2chr2:65492309chr2:64109599ENST00000337130210113_11685509.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000337130210115_11685509.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000337130210251_25385509.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000337130210457_50885509.0RegionNote=Oligomerization
TgeneUGP2chr2:65492309chr2:64109599ENST00000394417210113_11674498.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000394417210115_11674498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000394417210251_25374498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000394417210457_50874498.0RegionNote=Oligomerization
TgeneUGP2chr2:65492309chr2:64109599ENST00000467648311113_11674498.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000467648311115_11674498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000467648311251_25374498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109599ENST00000467648311457_50874498.0RegionNote=Oligomerization
TgeneUGP2chr2:65492309chr2:64109600ENST00000337130210113_11685509.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000337130210115_11685509.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000337130210251_25385509.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000337130210457_50885509.0RegionNote=Oligomerization
TgeneUGP2chr2:65492309chr2:64109600ENST00000394417210113_11674498.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000394417210115_11674498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000394417210251_25374498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000394417210457_50874498.0RegionNote=Oligomerization
TgeneUGP2chr2:65492309chr2:64109600ENST00000467648311113_11674498.0RegionUTP binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000467648311115_11674498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000467648311251_25374498.0RegionSubstrate binding
TgeneUGP2chr2:65492309chr2:64109600ENST00000467648311457_50874498.0RegionNote=Oligomerization

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for ACTR2-UGP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1839_1839_1_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109599_ENST00000394417_length(transcript)=2778nt_BP=1171nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGTTGGAAG
ACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTT
AGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACT
TAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTT
TGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGA
CTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGA
TATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGA
AAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGA
TGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGT
TGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACATTGTGCTTTCTGGAGGGTCTAC
TATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAAGGGTGATGTGGAAAAACTTTC
TATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGTGAAACTCAATGG
TGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCTGACTGTTCAGCA
AATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATACCAAAAAAATACT
ACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTTACTTCCTGTAGC
AAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTACAACTCTGGATT
GCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCTGTATATTCTTAA
TCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAAGGGCGGGACACT
CACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGTATCAAAGTTCAA
AATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGAAATCATTGTGAA
TGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAATTCTCTAGGTAT
TAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCTTAATGCAGGATC
TCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGATTATCTAAGAAG
ATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTCATTAAAGGGAAC
GGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGGAAACCTTCGCAT
CTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGATTCTAAAATAGGC
AGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAGAAAAGCACAGAT
GGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAATCTTAAAACTGGGCAACTTTG

>1839_1839_1_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109599_ENST00000394417_length(amino acids)=770AA_BP=347
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRN
WDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYE
GFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEA
PEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIKARGLP
DNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTF
NQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEF
VMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQL
ETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHL

--------------------------------------------------------------
>1839_1839_2_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109599_ENST00000467648_length(transcript)=2667nt_BP=1171nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGTTGGAAG
ACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTT
AGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACT
TAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTT
TGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGA
CTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGA
TATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGA
AAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGA
TGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGT
TGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACATTGTGCTTTCTGGAGGGTCTAC
TATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAAGGGTGATGTGGAAAAACTTTC
TATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGTGAAACTCAATGG
TGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCTGACTGTTCAGCA
AATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATACCAAAAAAATACT
ACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTTACTTCCTGTAGC
AAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTACAACTCTGGATT
GCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCTGTATATTCTTAA
TCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAAGGGCGGGACACT
CACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGTATCAAAGTTCAA
AATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGAAATCATTGTGAA
TGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAATTCTCTAGGTAT
TAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCTTAATGCAGGATC
TCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGATTATCTAAGAAG
ATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTCATTAAAGGGAAC
GGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGGAAACCTTCGCAT
CTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGATTCTAAAATAGGC
AGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAGAAAAGCACAGAT

>1839_1839_2_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109599_ENST00000467648_length(amino acids)=770AA_BP=347
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRN
WDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYE
GFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEA
PEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIKARGLP
DNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTF
NQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEF
VMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQL
ETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHL

--------------------------------------------------------------
>1839_1839_3_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109600_ENST00000394417_length(transcript)=2778nt_BP=1171nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGTTGGAAG
ACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTT
AGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACT
TAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTT
TGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGA
CTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGA
TATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGA
AAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGA
TGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGT
TGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACATTGTGCTTTCTGGAGGGTCTAC
TATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAAGGGTGATGTGGAAAAACTTTC
TATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGTGAAACTCAATGG
TGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCTGACTGTTCAGCA
AATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATACCAAAAAAATACT
ACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTTACTTCCTGTAGC
AAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTACAACTCTGGATT
GCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCTGTATATTCTTAA
TCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAAGGGCGGGACACT
CACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGTATCAAAGTTCAA
AATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGAAATCATTGTGAA
TGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAATTCTCTAGGTAT
TAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCTTAATGCAGGATC
TCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGATTATCTAAGAAG
ATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTCATTAAAGGGAAC
GGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGGAAACCTTCGCAT
CTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGATTCTAAAATAGGC
AGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAGAAAAGCACAGAT
GGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAATCTTAAAACTGGGCAACTTTG

>1839_1839_3_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109600_ENST00000394417_length(amino acids)=770AA_BP=347
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRN
WDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYE
GFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEA
PEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIKARGLP
DNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTF
NQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEF
VMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQL
ETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHL

--------------------------------------------------------------
>1839_1839_4_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109600_ENST00000467648_length(transcript)=2667nt_BP=1171nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGTTGGAAG
ACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTT
AGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACT
TAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTT
TGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGA
CTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGA
TATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGA
AAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGA
TGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGT
TGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACATTGTGCTTTCTGGAGGGTCTAC
TATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAAGGGTGATGTGGAAAAACTTTC
TATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGTGAAACTCAATGG
TGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCTGACTGTTCAGCA
AATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATACCAAAAAAATACT
ACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTTACTTCCTGTAGC
AAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTACAACTCTGGATT
GCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCTGTATATTCTTAA
TCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAAGGGCGGGACACT
CACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGTATCAAAGTTCAA
AATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGAAATCATTGTGAA
TGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAATTCTCTAGGTAT
TAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCTTAATGCAGGATC
TCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGATTATCTAAGAAG
ATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTCATTAAAGGGAAC
GGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGGAAACCTTCGCAT
CTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGATTCTAAAATAGGC
AGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAGAAAAGCACAGAT

>1839_1839_4_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000260641_UGP2_chr2_64109600_ENST00000467648_length(amino acids)=770AA_BP=347
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRN
WDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYE
GFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEA
PEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIKARGLP
DNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTF
NQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEF
VMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQL
ETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHL

--------------------------------------------------------------
>1839_1839_5_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109599_ENST00000394417_length(transcript)=2709nt_BP=1102nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGT
TGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGAATAACAAAAAGATGGATCTTATGGTTGGTGATGAGGC
AAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTA
CACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGA
GAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTT
ATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAG
ACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGA
AACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGT
TGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGAT
CAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACAT
TGTGCTTTCTGGAGGGTCTACTATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAA
GGGTGATGTGGAAAAACTTTCTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACT
AGTGGTGGTGAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTT
TCTGGATCTGACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGA
TGAAGATACCAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAA
AGAATCTTTACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGC
CAGTTTCTACAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCAC
AGTGGATCTGTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGC
AGATGTAAAGGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTT
CAAGTCTGTATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCAT
TGACATGGAAATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAG
TTTTGAGAATTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCT
CTATAGTCTTAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAA
GGTTCAAGATTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAA
AAATGTTTCATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGAT
TGTGTCTGGAAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTT
CTCTAGGATTCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTT
TAGTCTAAGAAAAGCACAGATGGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAA
TCTTAAAACTGGGCAACTTTGGAAGAACTTTTAACAGAAGCCTCAATGATGATCACTTTGAATTGCTTGTGATTTCAAAAATAAAGCAGT

>1839_1839_5_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109599_ENST00000394417_length(amino acids)=775AA_BP=352
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSMLEVNYPMEN
GIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHI
CPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGG
ERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIK
ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRV
KIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNG
KRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGL
NVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDML

--------------------------------------------------------------
>1839_1839_6_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109599_ENST00000467648_length(transcript)=2598nt_BP=1102nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGT
TGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGAATAACAAAAAGATGGATCTTATGGTTGGTGATGAGGC
AAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTA
CACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGA
GAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTT
ATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAG
ACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGA
AACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGT
TGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGAT
CAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACAT
TGTGCTTTCTGGAGGGTCTACTATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAA
GGGTGATGTGGAAAAACTTTCTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACT
AGTGGTGGTGAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTT
TCTGGATCTGACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGA
TGAAGATACCAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAA
AGAATCTTTACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGC
CAGTTTCTACAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCAC
AGTGGATCTGTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGC
AGATGTAAAGGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTT
CAAGTCTGTATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCAT
TGACATGGAAATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAG
TTTTGAGAATTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCT
CTATAGTCTTAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAA
GGTTCAAGATTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAA
AAATGTTTCATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGAT
TGTGTCTGGAAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTT
CTCTAGGATTCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTT

>1839_1839_6_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109599_ENST00000467648_length(amino acids)=775AA_BP=352
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSMLEVNYPMEN
GIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHI
CPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGG
ERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIK
ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRV
KIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNG
KRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGL
NVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDML

--------------------------------------------------------------
>1839_1839_7_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109600_ENST00000394417_length(transcript)=2709nt_BP=1102nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGT
TGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGAATAACAAAAAGATGGATCTTATGGTTGGTGATGAGGC
AAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTA
CACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGA
GAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTT
ATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAG
ACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGA
AACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGT
TGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGAT
CAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACAT
TGTGCTTTCTGGAGGGTCTACTATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAA
GGGTGATGTGGAAAAACTTTCTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACT
AGTGGTGGTGAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTT
TCTGGATCTGACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGA
TGAAGATACCAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAA
AGAATCTTTACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGC
CAGTTTCTACAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCAC
AGTGGATCTGTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGC
AGATGTAAAGGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTT
CAAGTCTGTATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCAT
TGACATGGAAATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAG
TTTTGAGAATTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCT
CTATAGTCTTAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAA
GGTTCAAGATTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAA
AAATGTTTCATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGAT
TGTGTCTGGAAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTT
CTCTAGGATTCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTT
TAGTCTAAGAAAAGCACAGATGGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAA
TCTTAAAACTGGGCAACTTTGGAAGAACTTTTAACAGAAGCCTCAATGATGATCACTTTGAATTGCTTGTGATTTCAAAAATAAAGCAGT

>1839_1839_7_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109600_ENST00000394417_length(amino acids)=775AA_BP=352
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSMLEVNYPMEN
GIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHI
CPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGG
ERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIK
ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRV
KIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNG
KRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGL
NVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDML

--------------------------------------------------------------
>1839_1839_8_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109600_ENST00000467648_length(transcript)=2598nt_BP=1102nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTTTGGT
TGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGAATAACAAAAAGATGGATCTTATGGTTGGTGATGAGGC
AAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATGACATGAAACACCTGTGGGACTA
CACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTATGAACCCAACCAAAAACAGAGA
GAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTCTGACTTTGTACGCTCAAGGTTT
ATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTTCTCTCCCTCATCTTACCAGGAG
ACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCTTCAACCACTCTGCTGATTTTGA
AACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGGCCTTAGAAACCACAGTATTAGT
TGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAGCTTTATTTCAGCCTCACTTGAT
CAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCAGATCTGAATTCTACAAACACAT
TGTGCTTTCTGGAGGGTCTACTATGTATCCTGGCCTGCCATCACGGTTGGAACGAGAACTTAAACAGCTTTACTTAGAACGAGTTTTGAA
GGGTGATGTGGAAAAACTTTCTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACT
AGTGGTGGTGAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTT
TCTGGATCTGACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGA
TGAAGATACCAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAA
AGAATCTTTACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGC
CAGTTTCTACAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCAC
AGTGGATCTGTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGC
AGATGTAAAGGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTT
CAAGTCTGTATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCAT
TGACATGGAAATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAG
TTTTGAGAATTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCT
CTATAGTCTTAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAA
GGTTCAAGATTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAA
AAATGTTTCATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGAT
TGTGTCTGGAAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTT
CTCTAGGATTCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTT

>1839_1839_8_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000377982_UGP2_chr2_64109600_ENST00000467648_length(amino acids)=775AA_BP=352
MQRLFPGRTMDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTTKVGNIEIKNNKKMDLMVGDEASELRSMLEVNYPMEN
GIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPMNPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVTHI
CPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGG
ERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVEKLSIQPYEKIK
ARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRV
KIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNG
KRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGL
NVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDML

--------------------------------------------------------------
>1839_1839_9_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109599_ENST00000394417_length(transcript)=2880nt_BP=1273nt
AAGAGGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGG
GCAGGAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTT
TGGTTGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGCCTTATTTTTTGAACAATTGAGCAAAAGAAACA
GATGAAACCTCATACAAAACCCTCCAAAATATGAAAATGTGGGGTTTATTTGTGCTAATGCTCTTCTTTTGGAAACATTTGTGTTAAAGG
ATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATG
ACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTA
TGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTC
TGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTT
CTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCT
TCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGG
CCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAG
CTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCA
GGTAAGTATTAGTAAATCAACTATTACTAACATTCTTTTAAAAGGCTATACAGTAGTTTGTGAATCTTGACAACCACCAGAGGGAGCAAG
ACGTCTTCCAAAACAAATTCCTACTGCAGTCAAGTGCATCCTGGAAATGATAGCAAGAAGGAAATAGTTCAAGATAAGCTCTGGTCACCT
CTATAGAGTTGGTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGT
GAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCT
GACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATAC
CAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTT
ACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTA
CAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCT
GTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAA
GGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGT
ATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGA
AATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAA
TTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCT
TAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGA
TTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTC
ATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGG
AAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGAT
TCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAG
AAAAGCACAGATGGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAATCTTAAAAC
TGGGCAACTTTGGAAGAACTTTTAACAGAAGCCTCAATGATGATCACTTTGAATTGCTTGTGATTTCAAAAATAAAGCAGTGAAGCAATA

>1839_1839_9_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109599_ENST00000394417_length(amino acids)=412AA_BP=
MPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIY
TFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRC
EFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVI
QLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELD

--------------------------------------------------------------
>1839_1839_10_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109599_ENST00000467648_length(transcript)=2769nt_BP=1273nt
AAGAGGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGG
GCAGGAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTT
TGGTTGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGCCTTATTTTTTGAACAATTGAGCAAAAGAAACA
GATGAAACCTCATACAAAACCCTCCAAAATATGAAAATGTGGGGTTTATTTGTGCTAATGCTCTTCTTTTGGAAACATTTGTGTTAAAGG
ATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATG
ACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTA
TGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTC
TGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTT
CTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCT
TCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGG
CCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAG
CTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCA
GGTAAGTATTAGTAAATCAACTATTACTAACATTCTTTTAAAAGGCTATACAGTAGTTTGTGAATCTTGACAACCACCAGAGGGAGCAAG
ACGTCTTCCAAAACAAATTCCTACTGCAGTCAAGTGCATCCTGGAAATGATAGCAAGAAGGAAATAGTTCAAGATAAGCTCTGGTCACCT
CTATAGAGTTGGTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGT
GAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCT
GACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATAC
CAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTT
ACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTA
CAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCT
GTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAA
GGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGT
ATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGA
AATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAA
TTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCT
TAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGA
TTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTC
ATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGG
AAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGAT
TCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAG

>1839_1839_10_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109599_ENST00000467648_length(amino acids)=412AA_BP=
MPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIY
TFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRC
EFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVI
QLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELD

--------------------------------------------------------------
>1839_1839_11_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109600_ENST00000394417_length(transcript)=2880nt_BP=1273nt
AAGAGGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGG
GCAGGAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTT
TGGTTGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGCCTTATTTTTTGAACAATTGAGCAAAAGAAACA
GATGAAACCTCATACAAAACCCTCCAAAATATGAAAATGTGGGGTTTATTTGTGCTAATGCTCTTCTTTTGGAAACATTTGTGTTAAAGG
ATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATG
ACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTA
TGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTC
TGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTT
CTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCT
TCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGG
CCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAG
CTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCA
GGTAAGTATTAGTAAATCAACTATTACTAACATTCTTTTAAAAGGCTATACAGTAGTTTGTGAATCTTGACAACCACCAGAGGGAGCAAG
ACGTCTTCCAAAACAAATTCCTACTGCAGTCAAGTGCATCCTGGAAATGATAGCAAGAAGGAAATAGTTCAAGATAAGCTCTGGTCACCT
CTATAGAGTTGGTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGT
GAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCT
GACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATAC
CAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTT
ACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTA
CAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCT
GTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAA
GGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGT
ATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGA
AATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAA
TTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCT
TAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGA
TTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTC
ATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGG
AAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGAT
TCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAG
AAAAGCACAGATGGAGCAATACTTTCCTTCTTTGAAGAGAATCCCAAAAGTTAGTTCATCTTAAAGTGCAATATTGTTTAATCTTAAAAC
TGGGCAACTTTGGAAGAACTTTTAACAGAAGCCTCAATGATGATCACTTTGAATTGCTTGTGATTTCAAAAATAAAGCAGTGAAGCAATA

>1839_1839_11_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109600_ENST00000394417_length(amino acids)=412AA_BP=
MPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIY
TFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRC
EFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVI
QLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELD

--------------------------------------------------------------
>1839_1839_12_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109600_ENST00000467648_length(transcript)=2769nt_BP=1273nt
AAGAGGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGG
GCAGGAAGGTGGTGGTGTGCGACAACGGCACCGGGTTTGTGAAGTGTGGATATGCAGGCTCTAACTTTCCAGAACACATCTTCCCAGCTT
TGGTTGGAAGACCTATTATCAGATCAACCACCAAAGTGGGAAACATTGAAATCAAGGCCTTATTTTTTGAACAATTGAGCAAAAGAAACA
GATGAAACCTCATACAAAACCCTCCAAAATATGAAAATGTGGGGTTTATTTGTGCTAATGCTCTTCTTTTGGAAACATTTGTGTTAAAGG
ATCTTATGGTTGGTGATGAGGCAAGTGAATTACGATCAATGTTAGAAGTTAACTACCCTATGGAAAATGGCATAGTACGAAATTGGGATG
ACATGAAACACCTGTGGGACTACACATTTGGACCAGAGAAACTTAATATAGATACCAGAAATTGTAAAATCTTACTCACAGAACCTCCTA
TGAACCCAACCAAAAACAGAGAGAAGATTGTAGAGGTAATGTTTGAAACTTACCAGTTTTCCGGTGTATATGTAGCCATCCAGGCAGTTC
TGACTTTGTACGCTCAAGGTTTATTGACTGGTGTAGTGGTAGACTCTGGAGATGGTGTGACTCACATTTGCCCAGTATATGAAGGCTTTT
CTCTCCCTCATCTTACCAGGAGACTGGATATTGCTGGGAGGGATATAACTAGATATCTTATCAAGCTACTTCTGTTGCGAGGATACGCCT
TCAACCACTCTGCTGATTTTGAAACGGTTCGCATGATTAAAGAAAAACTGTGTTACGTGGGATATAATATTGAGCAAGAGCAGAAACTGG
CCTTAGAAACCACAGTATTAGTTGAATCTTATACACTCCCAGATGGACGTATCATCAAAGTTGGGGGAGAGAGATTTGAAGCACCAGAAG
CTTTATTTCAGCCTCACTTGATCAATGTTGAAGGAGTTGGTGTTGCTGAATTGCTTTTTAACACAATTCAGGCAGCTGACATTGATACCA
GGTAAGTATTAGTAAATCAACTATTACTAACATTCTTTTAAAAGGCTATACAGTAGTTTGTGAATCTTGACAACCACCAGAGGGAGCAAG
ACGTCTTCCAAAACAAATTCCTACTGCAGTCAAGTGCATCCTGGAAATGATAGCAAGAAGGAAATAGTTCAAGATAAGCTCTGGTCACCT
CTATAGAGTTGGTATTCAACCCTATGAAAAGATAAAGGCCAGGGGCTTGCCTGATAATATATCTTCCGTGTTGAACAAACTAGTGGTGGT
GAAACTCAATGGTGGTTTGGGAACCAGCATGGGCTGCAAAGGCCCTAAAAGTCTGATTGGTGTGAGGAATGAGAATACCTTTCTGGATCT
GACTGTTCAGCAAATTGAACATTTGAATAAAACCTACAATACAGATGTTCCTCTTGTTTTAATGAACTCTTTTAACACGGATGAAGATAC
CAAAAAAATACTACAGAAGTACAATCATTGTCGTGTGAAAATCTACACTTTCAATCAAAGCAGGTACCCGAGGATTAATAAAGAATCTTT
ACTTCCTGTAGCAAAGGACGTGTCTTACTCAGGGGAAAATACAGAAGCTTGGTACCCTCCAGGTCATGGTGATATTTACGCCAGTTTCTA
CAACTCTGGATTGCTTGATACCTTTATAGGAGAAGGCAAAGAGTATATTTTTGTGTCTAACATAGATAATCTGGGTGCCACAGTGGATCT
GTATATTCTTAATCATCTAATGAACCCACCCAATGGAAAACGCTGTGAATTTGTCATGGAAGTCACAAATAAAACACGTGCAGATGTAAA
GGGCGGGACACTCACTCAATATGAAGGCAAACTGAGACTGGTGGAAATTGCTCAAGTGCCAAAAGCACATGTAGACGAGTTCAAGTCTGT
ATCAAAGTTCAAAATATTTAATACAAACAACCTATGGATTTCTCTTGCAGCAGTTAAAAGACTGCAGGAGCAAAATGCCATTGACATGGA
AATCATTGTGAATGCAAAGACTTTGGATGGAGGCCTGAATGTCATTCAATTAGAAACTGCAGTAGGGGCTGCCATCAAAAGTTTTGAGAA
TTCTCTAGGTATTAATGTGCCAAGGAGCCGTTTTCTGCCTGTCAAAACCACATCAGATCTCTTGCTGGTGATGTCAAACCTCTATAGTCT
TAATGCAGGATCTCTGACAATGAGTGAAAAGCGGGAATTTCCTACAGTGCCCTTGGTTAAATTAGGCAGTTCTTTTACGAAGGTTCAAGA
TTATCTAAGAAGATTTGAAAGTATACCAGATATGCTTGAATTGGATCACCTCACAGTTTCAGGAGATGTGACATTTGGAAAAAATGTTTC
ATTAAAGGGAACGGTTATCATCATTGCAAATCATGGTGACAGAATTGATATCCCACCTGGAGCAGTATTAGAGAACAAGATTGTGTCTGG
AAACCTTCGCATCTTGGACCACTGAAATGAAAAATACTGTGGACACTTAAATAATGGGCTAGTTTCTTACAATGAAATGTTCTCTAGGAT
TCTAAAATAGGCAGGTACTTTACTATGTTACTGTACCCTGCAGTGTTGATTTTTAAAATAGAGTTTTCTGCAGTATGCTTTTAGTCTAAG

>1839_1839_12_ACTR2-UGP2_ACTR2_chr2_65492309_ENST00000542850_UGP2_chr2_64109600_ENST00000467648_length(amino acids)=412AA_BP=
MPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIY
TFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRC
EFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVI
QLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACTR2-UGP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACTR2-UGP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACTR2-UGP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACTR2C0036341Schizophrenia1PSYGENET
TgeneC0036572Seizures1GENOMICS_ENGLAND
TgeneC0232466Feeding difficulties1GENOMICS_ENGLAND
TgeneC0557874Global developmental delay1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC4025846Abnormality of vision1GENOMICS_ENGLAND
TgeneC4025871Abnormality of the face1GENOMICS_ENGLAND