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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACTR2-TSGA10 (FusionGDB2 ID:HG10097TG80705)

Fusion Gene Summary for ACTR2-TSGA10

check button Fusion gene summary
Fusion gene informationFusion gene name: ACTR2-TSGA10
Fusion gene ID: hg10097tg80705
HgeneTgene
Gene symbol

ACTR2

TSGA10

Gene ID

10097

80705

Gene nameactin related protein 2testis specific 10
SynonymsARP2CEP4L|CT79|SPGF26
Cytomap('ACTR2')('TSGA10')

2p14

2q11.2

Type of geneprotein-codingprotein-coding
Descriptionactin-related protein 2ARP2 actin related protein 2 homologactin-like protein 2testis-specific gene 10 proteincancer/testis antigen 79testis development protein NYD-SP7testis-specific 10 protein
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000476840, ENST00000260641, 
ENST00000377982, ENST00000542850, 
Fusion gene scores* DoF score8 X 8 X 5=3206 X 6 X 4=144
# samples 97
** MAII scorelog2(9/320*10)=-1.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/144*10)=-1.04064198449735
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACTR2 [Title/Abstract] AND TSGA10 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACTR2(65455091)-TSGA10(99722160), # samples:3
Anticipated loss of major functional domain due to fusion event.ACTR2-TSGA10 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTR2-TSGA10 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTR2-TSGA10 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ACTR2-TSGA10 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACTR2

GO:0034314

Arp2/3 complex-mediated actin nucleation

11741539|17220302|29925947

HgeneACTR2

GO:0045944

positive regulation of transcription by RNA polymerase II

17220302

HgeneACTR2

GO:1905168

positive regulation of double-strand break repair via homologous recombination

29925947

HgeneACTR2

GO:2001032

regulation of double-strand break repair via nonhomologous end joining

29925947


check buttonFusion gene breakpoints across ACTR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TSGA10 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-22-5492-01AACTR2chr2

65455091

-TSGA10chr2

99722160

-
ChimerDB4LUSCTCGA-22-5492-01AACTR2chr2

65455091

+TSGA10chr2

99722160

-
ChimerDB4LUSCTCGA-22-5492ACTR2chr2

65455091

+TSGA10chr2

99688337

-
ChimerDB4LUSCTCGA-22-5492ACTR2chr2

65455091

+TSGA10chr2

99722160

-


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Fusion Gene ORF analysis for ACTR2-TSGA10

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000476840ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-3CDSENST00000476840ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99688337

-
3UTR-3CDSENST00000476840ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-3CDSENST00000476840ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99688337

-
3UTR-3CDSENST00000476840ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-3CDSENST00000476840ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99688337

-
3UTR-3CDSENST00000476840ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-3CDSENST00000476840ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99688337

-
3UTR-3CDSENST00000476840ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-3CDSENST00000476840ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99688337

-
3UTR-5UTRENST00000476840ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99722160

-
3UTR-5UTRENST00000476840ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5CDS-5UTRENST00000260641ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5CDS-5UTRENST00000260641ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5CDS-5UTRENST00000377982ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5CDS-5UTRENST00000377982ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-3CDSENST00000542850ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-3CDSENST00000542850ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-3CDSENST00000542850ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-3CDSENST00000542850ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-3CDSENST00000542850ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-3CDSENST00000542850ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-3CDSENST00000542850ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-3CDSENST00000542850ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-3CDSENST00000542850ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-3CDSENST00000542850ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99688337

-
5UTR-5UTRENST00000542850ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99722160

-
5UTR-5UTRENST00000542850ENST00000478090ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000260641ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000260641ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000260641ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000260641ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000260641ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000377982ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000377982ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000377982ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000377982ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99688337

-
Frame-shiftENST00000377982ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99688337

-
In-frameENST00000260641ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000260641ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000260641ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000260641ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000260641ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000377982ENST00000355053ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000377982ENST00000393483ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000377982ENST00000410001ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000377982ENST00000539964ACTR2chr2

65455091

+TSGA10chr2

99722160

-
In-frameENST00000377982ENST00000542655ACTR2chr2

65455091

+TSGA10chr2

99722160

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000260641ACTR2chr265455091+ENST00000393483TSGA10chr299722160-30282051302091653
ENST00000260641ACTR2chr265455091+ENST00000410001TSGA10chr299722160-24032051302091653
ENST00000260641ACTR2chr265455091+ENST00000355053TSGA10chr299722160-24032051302091653
ENST00000260641ACTR2chr265455091+ENST00000539964TSGA10chr299722160-20922051302091654
ENST00000260641ACTR2chr265455091+ENST00000542655TSGA10chr299722160-946205130888252
ENST00000377982ACTR2chr265455091+ENST00000393483TSGA10chr299722160-2944121462007653
ENST00000377982ACTR2chr265455091+ENST00000410001TSGA10chr299722160-2319121462007653
ENST00000377982ACTR2chr265455091+ENST00000355053TSGA10chr299722160-2319121462007653
ENST00000377982ACTR2chr265455091+ENST00000539964TSGA10chr299722160-2008121462007654
ENST00000377982ACTR2chr265455091+ENST00000542655TSGA10chr299722160-86212146804252

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260641ENST00000393483ACTR2chr265455091+TSGA10chr299722160-0.0003068020.9996933
ENST00000260641ENST00000410001ACTR2chr265455091+TSGA10chr299722160-0.0011520280.99884796
ENST00000260641ENST00000355053ACTR2chr265455091+TSGA10chr299722160-0.0011520280.99884796
ENST00000260641ENST00000539964ACTR2chr265455091+TSGA10chr299722160-0.0020247520.9979753
ENST00000260641ENST00000542655ACTR2chr265455091+TSGA10chr299722160-0.0080809960.991919
ENST00000377982ENST00000393483ACTR2chr265455091+TSGA10chr299722160-0.0003169840.999683
ENST00000377982ENST00000410001ACTR2chr265455091+TSGA10chr299722160-0.0012587190.9987413
ENST00000377982ENST00000355053ACTR2chr265455091+TSGA10chr299722160-0.0012587190.9987413
ENST00000377982ENST00000539964ACTR2chr265455091+TSGA10chr299722160-0.0022709590.997729
ENST00000377982ENST00000542655ACTR2chr265455091+TSGA10chr299722160-0.0089545530.9910454

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Fusion Genomic Features for ACTR2-TSGA10


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACTR2-TSGA10


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:65455091/chr2:99722160)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTR2chr2:65455091chr2:99722160ENST00000260641+19160_16216395.0Nucleotide bindingATP
HgeneACTR2chr2:65455091chr2:99722160ENST00000260641+19214_21816395.0Nucleotide bindingATP
HgeneACTR2chr2:65455091chr2:99722160ENST00000260641+19305_31016395.0Nucleotide bindingATP
HgeneACTR2chr2:65455091chr2:99722160ENST00000377982+110160_16216400.0Nucleotide bindingATP
HgeneACTR2chr2:65455091chr2:99722160ENST00000377982+110214_21816400.0Nucleotide bindingATP
HgeneACTR2chr2:65455091chr2:99722160ENST00000377982+110305_31016400.0Nucleotide bindingATP


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Fusion Gene Sequence for ACTR2-TSGA10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1837_1837_1_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000355053_length(transcript)=2403nt_BP=205nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAAATCAAC
AACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGATAGTCT
AAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTACAGTTCA
TAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAAATCACT
AGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACACAGAAAA
AGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGAAAAAAT
TGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAAGGAATG
CCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGGCATGAA
GAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCGTCGGCA
ATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACAGTTTGC
TAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCAAGATAC
TAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGCCAATGA
AGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGCAGAGGG
TAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGATTTCTAC
CTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTCTACTAG
GGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGAGAATGA
GTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTTGCTGGT
GGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTGTTTGGC
AGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTACCAAAAG
ACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATATGAGTTC
TACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGAAGAGAA
TCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTTTTGCTA
CATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGCCATGTT
GCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTTACTTCA

>1837_1837_1_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000355053_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_2_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000393483_length(transcript)=3028nt_BP=205nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAAATCAAC
AACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGATAGTCT
AAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTACAGTTCA
TAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAAATCACT
AGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACACAGAAAA
AGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGAAAAAAT
TGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAAGGAATG
CCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGGCATGAA
GAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCGTCGGCA
ATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACAGTTTGC
TAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCAAGATAC
TAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGCCAATGA
AGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGCAGAGGG
TAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGATTTCTAC
CTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTCTACTAG
GGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGAGAATGA
GTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTTGCTGGT
GGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTGTTTGGC
AGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTACCAAAAG
ACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATATGAGTTC
TACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGAAGAGAA
TCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTTTTGCTA
CATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGCCATGTT
GCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTTACTTCA
CTATTGAACACTATTCTGTTCACTATCTGGAGTAAATAAAGAAGCTTATTAAAACAGGGAAAAGTGTTTTTACAAAACTGCTTTCCTTTC
CTTTCTTGGTATCTCAAATAATTGGTTGGTTAATTTTTTTTCTTTGTGATTTGTGTTTTCATGGCTGGAAAATCTGTGCCAAAATGGGTA
CAACTTACTGATACTGGTCTGGGATCTGATATTCCATTTTGGAACCAACCTTACATGAATTCCATGCCATAATCTGATATTGAAGCAGCA
GAAAGTAGGAGTGTTGTCAGGGTTTTAAAACCTATAGTATTGTACCACTCAAAGACTAAGTAACATACATATTCTACAATTGTGTTTACT
ACTACTGCTTTTAGAAAGGTAGGTGATGGTATATCTGTCAAGAATGTAAGATTTTATTAAAAATCTTTATTTTTAATAAGTTTTCTTTCA
AGTACTGCAATCAACTTAATTGCGATTTTATTTTATTGTCTGTGGCAGCTGTCTGTAATCTGGAGTAATAAGATAAGTGATGTTTCCTTC
CTCCCCCAATTTCCTAAATCTCTTACCTTATCTATCCATAGGCTTTGATGTAATGTTCATATTAGAGCCTGAATGCTACTGTATTTTACT

>1837_1837_2_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000393483_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_3_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000410001_length(transcript)=2403nt_BP=205nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAAATCAAC
AACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGATAGTCT
AAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTACAGTTCA
TAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAAATCACT
AGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACACAGAAAA
AGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGAAAAAAT
TGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAAGGAATG
CCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGGCATGAA
GAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCGTCGGCA
ATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACAGTTTGC
TAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCAAGATAC
TAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGCCAATGA
AGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGCAGAGGG
TAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGATTTCTAC
CTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTCTACTAG
GGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGAGAATGA
GTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTTGCTGGT
GGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTGTTTGGC
AGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTACCAAAAG
ACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATATGAGTTC
TACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGAAGAGAA
TCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTTTTGCTA
CATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGCCATGTT
GCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTTACTTCA

>1837_1837_3_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000410001_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_4_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000539964_length(transcript)=2092nt_BP=205nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAAATCAAC
AACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGATAGTCT
AAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTACAGTTCA
TAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAAATCACT
AGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACACAGAAAA
AGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGAAAAAAT
TGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAAGGAATG
CCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGGCATGAA
GAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCGTCGGCA
ATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACAGTTTGC
TAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCAAGATAC
TAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGCCAATGA
AGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGCAGAGGG
TAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGATTTCTAC
CTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTCTACTAG
GGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGAGAATGA
GTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTTGCTGGT
GGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTGTTTGGC
AGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTACCAAAAG
ACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATATGAGTTC
TACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGAAGAGAA

>1837_1837_4_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000539964_length(amino acids)=654AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_5_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000542655_length(transcript)=946nt_BP=205nt
AGCTAAATGACGGGCGGAGCCCGGCGGCGGCTTCCGGTCGGGGGAAAAAAGTTGGGCCGAAGGAGGGGCCGGGAAGACGCAAGAGGAAGA
AGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAGGAAGGT
GGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAAATCAAC
AACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGATAGTCT
AAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTACAGTTCA
TAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAAATCACT
AGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACACAGAAAA
AGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGAAAAAAT
TGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAAGGAATG
CCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAACAGTGTACTGAGGCCCTAATTG

>1837_1837_5_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000260641_TSGA10_chr2_99722160_ENST00000542655_length(amino acids)=252AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK

--------------------------------------------------------------
>1837_1837_6_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000355053_length(transcript)=2319nt_BP=121nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAA
ATCAACAACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGA
TAGTCTAAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTAC
AGTTCATAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAA
ATCACTAGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACAC
AGAAAAAGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGA
AAAAATTGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAA
GGAATGCCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGG
CATGAAGAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCG
TCGGCAATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACA
GTTTGCTAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCA
AGATACTAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGC
CAATGAAGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGC
AGAGGGTAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGAT
TTCTACCTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTC
TACTAGGGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGA
GAATGAGTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTT
GCTGGTGGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTG
TTTGGCAGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTAC
CAAAAGACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATAT
GAGTTCTACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGA
AGAGAATCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTT
TTGCTACATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGC
CATGTTGCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTT

>1837_1837_6_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000355053_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_7_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000393483_length(transcript)=2944nt_BP=121nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAA
ATCAACAACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGA
TAGTCTAAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTAC
AGTTCATAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAA
ATCACTAGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACAC
AGAAAAAGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGA
AAAAATTGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAA
GGAATGCCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGG
CATGAAGAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCG
TCGGCAATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACA
GTTTGCTAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCA
AGATACTAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGC
CAATGAAGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGC
AGAGGGTAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGAT
TTCTACCTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTC
TACTAGGGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGA
GAATGAGTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTT
GCTGGTGGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTG
TTTGGCAGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTAC
CAAAAGACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATAT
GAGTTCTACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGA
AGAGAATCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTT
TTGCTACATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGC
CATGTTGCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTT
ACTTCACTATTGAACACTATTCTGTTCACTATCTGGAGTAAATAAAGAAGCTTATTAAAACAGGGAAAAGTGTTTTTACAAAACTGCTTT
CCTTTCCTTTCTTGGTATCTCAAATAATTGGTTGGTTAATTTTTTTTCTTTGTGATTTGTGTTTTCATGGCTGGAAAATCTGTGCCAAAA
TGGGTACAACTTACTGATACTGGTCTGGGATCTGATATTCCATTTTGGAACCAACCTTACATGAATTCCATGCCATAATCTGATATTGAA
GCAGCAGAAAGTAGGAGTGTTGTCAGGGTTTTAAAACCTATAGTATTGTACCACTCAAAGACTAAGTAACATACATATTCTACAATTGTG
TTTACTACTACTGCTTTTAGAAAGGTAGGTGATGGTATATCTGTCAAGAATGTAAGATTTTATTAAAAATCTTTATTTTTAATAAGTTTT
CTTTCAAGTACTGCAATCAACTTAATTGCGATTTTATTTTATTGTCTGTGGCAGCTGTCTGTAATCTGGAGTAATAAGATAAGTGATGTT
TCCTTCCTCCCCCAATTTCCTAAATCTCTTACCTTATCTATCCATAGGCTTTGATGTAATGTTCATATTAGAGCCTGAATGCTACTGTAT

>1837_1837_7_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000393483_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_8_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000410001_length(transcript)=2319nt_BP=121nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAA
ATCAACAACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGA
TAGTCTAAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTAC
AGTTCATAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAA
ATCACTAGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACAC
AGAAAAAGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGA
AAAAATTGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAA
GGAATGCCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGG
CATGAAGAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCG
TCGGCAATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACA
GTTTGCTAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCA
AGATACTAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGC
CAATGAAGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGC
AGAGGGTAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGAT
TTCTACCTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTC
TACTAGGGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGA
GAATGAGTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTT
GCTGGTGGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTG
TTTGGCAGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTAC
CAAAAGACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATAT
GAGTTCTACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGA
AGAGAATCTTTGCTACAGAGATTTCTGACACCTGAAATGATTCTTCACATCCCTGAGAAAGGTCAAAGTTACAAACTGATTTTTTTTTTT
TTGCTACATGAGTGCATTTATCTTTTAAATGCTTGGCAATGTTAAATGTATTTATTAACTTTGTGTCTCTGAATCTCTGTTCTAATGTGC
CATGTTGCAGTGATCTGAGATGACTTATAAAAACAAAAATGTATATGGCTCTTTCTATCCATGCAGTGATAGTGAGTGTAAAATCTGCTT

>1837_1837_8_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000410001_length(amino acids)=653AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_9_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000539964_length(transcript)=2008nt_BP=121nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAA
ATCAACAACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGA
TAGTCTAAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTAC
AGTTCATAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAA
ATCACTAGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACAC
AGAAAAAGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGA
AAAAATTGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAA
GGAATGCCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAGAAAAGACCATTTCAGG
CATGAAGAATATCATTGCTGAGATGGAACAGGCATCAAGACAGTGTACTGAGGCCCTAATTGTGTGTGAACAAGACGTTTCCAGAATGCG
TCGGCAATTGGATGAGACAAATGATGAGCTGGCCCAGATCGCCAGGGAAAGAGATATCTTGGCTCATGACAATGACAATCTCCAGGAACA
GTTTGCTAAAGCTAAACAAGAAAACCAGGCACTGTCCAAAAAATTGAATGACACTCATAATGAACTTAATGACATAAAACAGAAGGTTCA
AGATACTAATTTGGAGGTTAACAAGCTGAAGAATATATTAAAGTCTGAAGAATCTGAGAACCGGCAAATGATGGAACAACTTCGAAAAGC
CAATGAAGATGCTGAAAACTGGGAAAATAAAGCCCGTCAATCAGAGGCAGATAACAATACCCTCAAACTGGAACTTATCACTGCTGAGGC
AGAGGGTAACAGATTAAAAGAAAAAGTAGATTCCCTCAACAGAGAGGTTGAGCAACACTTAAATGCAGAAAGGTCTTACAAGTCCCAGAT
TTCTACCTTACATAAATCTGTTGTAAAAATGGAAGAGGAGCTTCAGAAGGTTCAGTTTGAAAAAGTGTCCGCTCTTGCAGATTTGTCTTC
TACTAGGGAACTCTGTATTAAACTTGACTCAAGCAAAGAACTTCTTAATCGACAGCTGGTTGCTAAAGATCAAGAAATAGAAATGAGGGA
GAATGAGTTAGATTCTGCTCATTCTGAAATTGAACTCCTGAGGAGTCAGATGGCAAATGAGAGAATCTCCATGCAGAATCTAGAAGCTTT
GCTGGTGGCCAATCGAGACAAAGAATATCAGTCTCAGATAGCACTTCAAGAAAAAGAATCTGAAATTCAGCTTCTTAAAGAACACCTTTG
TTTGGCAGAAAATAAAATGGCCATCCAGAGTAGAGATGTGGCCCAGTTCAGAAATGTTGTCACACAATTGGAAGCTGATTTAGACATTAC
CAAAAGACAACTAGGAACAGAGCGCTTTGAAAGGGAGAGGGCCGTACAAGAACTTCGCCGCCAAAATTATTCAAGTAATGCTTATCATAT
GAGTTCTACAATGAAGCCAAATACAAAATGTCATTCACCAGAACGTGCTCACCATCGATCTCCTGACCGAGGCCTAGATCGATCATTAGA

>1837_1837_9_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000539964_length(amino acids)=654AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK
YELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQC
TEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKS
EESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQ
KVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIAL
QEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQLEADLDITKRQLGTERFERERAVQELRRQNYSSNAYHMSSTMKPNTKCHSPER

--------------------------------------------------------------
>1837_1837_10_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000542655_length(transcript)=862nt_BP=121nt
GGAAGAAGAGAAAACGGCCGGGCGGCGGTGGCTGTAGGTTGTGCGGCTGCAGCGGCTCTTCCCTGGGCGGACGATGGACAGCCAGGGCAG
GAAGGTGGTGGTGTGCGACAACGGCACCGGGGCACAGGAAGAAATTACCCGACTTCGACGAGAAATGATGAAAAGCTGTAAGAGTCCTAA
ATCAACAACGGCACATGCTATTCTCCGGCGAGTGGAGACTGAAAGAGATGTAGCCTTTACTGATTTACGAAGAATGACCACAGAACGAGA
TAGTCTAAGGGAGAGGCTAAAGATTGCTCAAGAGACAGCATTTAATGAGAAGGCTCACCTGGAACAAAGGATAGAGGAGCTGGAGTGTAC
AGTTCATAATCTTGATGATGAACGTATGGAGCAAATGTCAAATATGACTTTGATGAAGGAAACCATAAGCACTGTGGAAAAAGAAATGAA
ATCACTAGCAAGAAAGGCAATGGATACCGAAAGTGAACTTGGCAGACAAAAAGCAGAGAATAATTCTTTGAGACTTTTGTATGAAAACAC
AGAAAAAGATCTTTCTGATACTCAGCGACACCTTGCTAAGAAAAAATATGAGCTACAGCTTACTCAGGAGAAAATTATGTGCTTGGATGA
AAAAATTGATAACTTTACAAGGCAAAATATTGCACAGCGAGAAGAAATCAGCATTCTTGGTGGAACCCTCAATGATCTGGCTAAAGAAAA
GGAATGCCTGCAAGCATGTTTGGATAAAAAATCTGAGAATATTGCATCCCTTGGAGAGAGTTTGGCAATGAAAACAGTGTACTGAGGCCC

>1837_1837_10_ACTR2-TSGA10_ACTR2_chr2_65455091_ENST00000377982_TSGA10_chr2_99722160_ENST00000542655_length(amino acids)=252AA_BP=25
MQRLFPGRTMDSQGRKVVVCDNGTGAQEEITRLRREMMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFN
EKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACTR2-TSGA10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneTSGA10chr2:65455091chr2:99722160ENST00000355053520556_68970.0699.0HIF1A
TgeneTSGA10chr2:65455091chr2:99722160ENST00000393483621556_68970.0699.0HIF1A
TgeneTSGA10chr2:65455091chr2:99722160ENST00000410001419556_68970.0699.0HIF1A
TgeneTSGA10chr2:65455091chr2:99722160ENST00000539964419556_68970.0699.0HIF1A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACTR2-TSGA10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACTR2-TSGA10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACTR2C0036341Schizophrenia1PSYGENET