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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CALCOCO2-WRAP53 (FusionGDB2 ID:HG10241TG55135)

Fusion Gene Summary for CALCOCO2-WRAP53

Fusion gene summary

Fusion gene information	Fusion gene name: CALCOCO2-WRAP53
	Fusion gene ID: hg10241tg55135
		Hgene	Tgene
	Gene symbol	CALCOCO2	WRAP53
	Gene ID	10241	55135
	Gene name	calcium binding and coiled-coil domain 2	WD repeat containing antisense to TP53
	Synonyms	NDP52	DKCB3\|TCAB1\|WDR79
	Cytomap	('CALCOCO2')('WRAP53') 17q21.32	17p13.1
	Type of gene	protein-coding	protein-coding
	Description	calcium-binding and coiled-coil domain-containing protein 2antigen nuclear dot 52 kDa proteinnuclear domain 10 protein 52nuclear domain 10 protein NDP52nuclear dot protein 52	telomerase Cajal body protein 1WD repeat-containing protein 79WD repeat-containing protein WRAP53WD40 protein Wrap53WD40 repeat-containing protein antisense to TP53WD40 repeat-containing protein encoding RNA antisense to p53WRAP53beta
	Modification date	20200327	20200315
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000258947, ENST00000416445, ENST00000448105, ENST00000508679, ENST00000509507, ENST00000510997,
Fusion gene scores	* DoF score	6 X 4 X 5=120	13 X 10 X 7=910
	# samples	7	16
	** MAII score	log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/910*10)=-2.5077946401987 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CALCOCO2 [Title/Abstract] AND WRAP53 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CALCOCO2(46933549)-WRAP53(7604059), # samples:2
Anticipated loss of major functional domain due to fusion event.	CALCOCO2-WRAP53 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CALCOCO2-WRAP53 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CALCOCO2-WRAP53 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CALCOCO2-WRAP53 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CALCOCO2	GO:0034341	response to interferon-gamma	9230084
Tgene	WRAP53	GO:0007004	telomere maintenance via telomerase	23685356\|29695869\|29804836
Tgene	WRAP53	GO:0034337	RNA folding	29804836
Tgene	WRAP53	GO:0045739	positive regulation of DNA repair	25512560
Tgene	WRAP53	GO:0051973	positive regulation of telomerase activity	19179534\|23685356\|29804836
Tgene	WRAP53	GO:0090666	scaRNA localization to Cajal body	19285445
Tgene	WRAP53	GO:1904867	protein localization to Cajal body	22547674
Tgene	WRAP53	GO:1905168	positive regulation of double-strand break repair via homologous recombination	25512560
Tgene	WRAP53	GO:2000781	positive regulation of double-strand break repair	27715493
Tgene	WRAP53	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	25512560

Fusion gene breakpoints across CALCOCO2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across WRAP53 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	SARC	TCGA-WK-A8XS-01A	CALCOCO2	chr17	46933549	-	WRAP53	chr17	7604059	+
ChimerDB4	SARC	TCGA-WK-A8XS-01A	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+

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Fusion Gene ORF analysis for CALCOCO2-WRAP53

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000258947	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000258947	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000258947	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000258947	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000258947	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000416445	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000416445	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000416445	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000416445	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000416445	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000448105	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000448105	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000448105	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000448105	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000448105	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000508679	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000508679	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000508679	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000508679	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000508679	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000509507	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000509507	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000509507	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000509507	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
In-frame	ENST00000509507	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
intron-3CDS	ENST00000510997	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
intron-3CDS	ENST00000510997	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
intron-3CDS	ENST00000510997	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
intron-3CDS	ENST00000510997	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+
intron-3CDS	ENST00000510997	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000258947	CALCOCO2	chr17	46933549	+	ENST00000431639	WRAP53	chr17	7604059	+	2130	1109	50	2113	687
ENST00000258947	CALCOCO2	chr17	46933549	+	ENST00000316024	WRAP53	chr17	7604059	+	2130	1109	50	2113	687
ENST00000258947	CALCOCO2	chr17	46933549	+	ENST00000457584	WRAP53	chr17	7604059	+	2130	1109	50	2113	687
ENST00000258947	CALCOCO2	chr17	46933549	+	ENST00000396463	WRAP53	chr17	7604059	+	2130	1109	50	2113	687
ENST00000258947	CALCOCO2	chr17	46933549	+	ENST00000534050	WRAP53	chr17	7604059	+	2130	1109	50	2113	687
ENST00000509507	CALCOCO2	chr17	46933549	+	ENST00000431639	WRAP53	chr17	7604059	+	2155	1134	12	2138	708
ENST00000509507	CALCOCO2	chr17	46933549	+	ENST00000316024	WRAP53	chr17	7604059	+	2155	1134	12	2138	708
ENST00000509507	CALCOCO2	chr17	46933549	+	ENST00000457584	WRAP53	chr17	7604059	+	2155	1134	12	2138	708
ENST00000509507	CALCOCO2	chr17	46933549	+	ENST00000396463	WRAP53	chr17	7604059	+	2155	1134	12	2138	708
ENST00000509507	CALCOCO2	chr17	46933549	+	ENST00000534050	WRAP53	chr17	7604059	+	2155	1134	12	2138	708
ENST00000448105	CALCOCO2	chr17	46933549	+	ENST00000431639	WRAP53	chr17	7604059	+	2156	1135	4	2139	711
ENST00000448105	CALCOCO2	chr17	46933549	+	ENST00000316024	WRAP53	chr17	7604059	+	2156	1135	4	2139	711
ENST00000448105	CALCOCO2	chr17	46933549	+	ENST00000457584	WRAP53	chr17	7604059	+	2156	1135	4	2139	711
ENST00000448105	CALCOCO2	chr17	46933549	+	ENST00000396463	WRAP53	chr17	7604059	+	2156	1135	4	2139	711
ENST00000448105	CALCOCO2	chr17	46933549	+	ENST00000534050	WRAP53	chr17	7604059	+	2156	1135	4	2139	711
ENST00000416445	CALCOCO2	chr17	46933549	+	ENST00000431639	WRAP53	chr17	7604059	+	1957	936	3	1940	645
ENST00000416445	CALCOCO2	chr17	46933549	+	ENST00000316024	WRAP53	chr17	7604059	+	1957	936	3	1940	645
ENST00000416445	CALCOCO2	chr17	46933549	+	ENST00000457584	WRAP53	chr17	7604059	+	1957	936	3	1940	645
ENST00000416445	CALCOCO2	chr17	46933549	+	ENST00000396463	WRAP53	chr17	7604059	+	1957	936	3	1940	645
ENST00000416445	CALCOCO2	chr17	46933549	+	ENST00000534050	WRAP53	chr17	7604059	+	1957	936	3	1940	645
ENST00000508679	CALCOCO2	chr17	46933549	+	ENST00000431639	WRAP53	chr17	7604059	+	1893	872	8	1876	622
ENST00000508679	CALCOCO2	chr17	46933549	+	ENST00000316024	WRAP53	chr17	7604059	+	1893	872	8	1876	622
ENST00000508679	CALCOCO2	chr17	46933549	+	ENST00000457584	WRAP53	chr17	7604059	+	1893	872	8	1876	622
ENST00000508679	CALCOCO2	chr17	46933549	+	ENST00000396463	WRAP53	chr17	7604059	+	1893	872	8	1876	622
ENST00000508679	CALCOCO2	chr17	46933549	+	ENST00000534050	WRAP53	chr17	7604059	+	1893	872	8	1876	622

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000258947	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00483215	0.99516785
ENST00000258947	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00483215	0.99516785
ENST00000258947	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00483215	0.99516785
ENST00000258947	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00483215	0.99516785
ENST00000258947	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00483215	0.99516785
ENST00000509507	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.004287577	0.9957124
ENST00000509507	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.004287577	0.9957124
ENST00000509507	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.004287577	0.9957124
ENST00000509507	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.004287577	0.9957124
ENST00000509507	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.004287577	0.9957124
ENST00000448105	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00810599	0.99189395
ENST00000448105	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00810599	0.99189395
ENST00000448105	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00810599	0.99189395
ENST00000448105	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00810599	0.99189395
ENST00000448105	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.00810599	0.99189395
ENST00000416445	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.002860856	0.9971392
ENST00000416445	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.002860856	0.9971392
ENST00000416445	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.002860856	0.9971392
ENST00000416445	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.002860856	0.9971392
ENST00000416445	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.002860856	0.9971392
ENST00000508679	ENST00000431639	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.005687274	0.99431276
ENST00000508679	ENST00000316024	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.005687274	0.99431276
ENST00000508679	ENST00000457584	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.005687274	0.99431276
ENST00000508679	ENST00000396463	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.005687274	0.99431276
ENST00000508679	ENST00000534050	CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604059	+	0.005687274	0.99431276

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Fusion Genomic Features for CALCOCO2-WRAP53

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604058	+	2.94E-07	0.99999976
CALCOCO2	chr17	46933549	+	WRAP53	chr17	7604058	+	2.94E-07	0.99999976

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CALCOCO2-WRAP53

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:46933549/chr17:7604059)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000448105

137_349

360

471.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000509507

137_349

357

468.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000258947

133_136

336

447.0

Motif

CLIR

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000416445

133_136

294

405.0

Motif

CLIR

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000448105

133_136

360

471.0

Motif

CLIR

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000508679

133_136

264

375.0

Motif

CLIR

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000509507

133_136

357

468.0

Motif

CLIR

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

222_267

214

549.0

Repeat

WD 2

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

272_313

214

549.0

Repeat

WD 3

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

323_364

214

549.0

Repeat

WD 4

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

365_405

214

549.0

Repeat

WD 5

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

411_450

214

549.0

Repeat

WD 6

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

222_267

214

549.0

Repeat

WD 2

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

272_313

214

549.0

Repeat

WD 3

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

323_364

214

549.0

Repeat

WD 4

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

365_405

214

549.0

Repeat

WD 5

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

411_450

214

549.0

Repeat

WD 6

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

222_267

214

549.0

Repeat

WD 2

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

272_313

214

549.0

Repeat

WD 3

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

323_364

214

549.0

Repeat

WD 4

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

365_405

214

549.0

Repeat

WD 5

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

411_450

214

549.0

Repeat

WD 6

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

222_267

214

549.0

Repeat

WD 2

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

272_313

214

549.0

Repeat

WD 3

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

323_364

214

549.0

Repeat

WD 4

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

365_405

214

549.0

Repeat

WD 5

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

411_450

214

549.0

Repeat

WD 6

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000258947

137_349

336

447.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000416445

137_349

294

405.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000508679

137_349

264

375.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000258947

419_444

336

447.0

Zinc finger

UBZ1-type

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000416445

419_444

294

405.0

Zinc finger

UBZ1-type

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000448105

419_444

360

471.0

Zinc finger

UBZ1-type

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000508679

419_444

264

375.0

Zinc finger

UBZ1-type

Hgene

CALCOCO2

chr17:46933549

chr17:7604059

ENST00000509507

419_444

357

468.0

Zinc finger

UBZ1-type

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

8_57

214

549.0

Compositional bias

Note=Pro-rich

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

8_57

214

549.0

Compositional bias

Note=Pro-rich

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

8_57

214

549.0

Compositional bias

Note=Pro-rich

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

8_57

214

549.0

Compositional bias

Note=Pro-rich

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000316024

167_206

214

549.0

Repeat

WD 1

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000396463

167_206

214

549.0

Repeat

WD 1

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000431639

167_206

214

549.0

Repeat

WD 1

Tgene

WRAP53

chr17:46933549

chr17:7604059

ENST00000457584

167_206

214

549.0

Repeat

WD 1

Top

Fusion Gene Sequence for CALCOCO2-WRAP53

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>12503_12503_1_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000316024_length(transcript)=2130nt_BP=1109nt
CAGGCGGGACGGGCTCTCCCTTGGGTGCTTAGCCCCGCCCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCT
GGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACA
GTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTG
GCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTA
AACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCC
GGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACTCAGGGAGAGGTGGAAGAGATTGAGC
AGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAGCAGAACTCAGACATGCAGGCTGAGC
TCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTATTGGGAGA
CAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAGGCCCAGC
TGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAAAATGACC
ACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACTACTGCAA
TGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTGCAGAGAC
AGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGA
TGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGAGAGCTCC
GGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTG
GCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAGGGCCAGA
GCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGG
ATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTCTTCTCAG
GAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATC
AGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACGGACGGGC
CTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTC
TCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCA
CGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGA

>12503_12503_1_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000316024_length(amino acids)=687AA_BP=353
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSC
ISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQD
KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMV
EGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRD
CEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSG
YPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTES

--------------------------------------------------------------
>12503_12503_2_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000396463_length(transcript)=2130nt_BP=1109nt
CAGGCGGGACGGGCTCTCCCTTGGGTGCTTAGCCCCGCCCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCT
GGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACA
GTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTG
GCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTA
AACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCC
GGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACTCAGGGAGAGGTGGAAGAGATTGAGC
AGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAGCAGAACTCAGACATGCAGGCTGAGC
TCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTATTGGGAGA
CAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAGGCCCAGC
TGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAAAATGACC
ACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACTACTGCAA
TGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTGCAGAGAC
AGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGA
TGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGAGAGCTCC
GGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTG
GCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAGGGCCAGA
GCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGG
ATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTCTTCTCAG
GAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATC
AGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACGGACGGGC
CTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTC
TCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCA
CGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGA

>12503_12503_2_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000396463_length(amino acids)=687AA_BP=353
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSC
ISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQD
KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMV
EGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRD
CEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSG
YPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTES

--------------------------------------------------------------
>12503_12503_3_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000431639_length(transcript)=2130nt_BP=1109nt
CAGGCGGGACGGGCTCTCCCTTGGGTGCTTAGCCCCGCCCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCT
GGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACA
GTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTG
GCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTA
AACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCC
GGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACTCAGGGAGAGGTGGAAGAGATTGAGC
AGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAGCAGAACTCAGACATGCAGGCTGAGC
TCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTATTGGGAGA
CAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAGGCCCAGC
TGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAAAATGACC
ACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACTACTGCAA
TGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTGCAGAGAC
AGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGA
TGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGAGAGCTCC
GGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTG
GCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAGGGCCAGA
GCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGG
ATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTCTTCTCAG
GAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATC
AGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACGGACGGGC
CTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTC
TCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCA
CGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGA

>12503_12503_3_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000431639_length(amino acids)=687AA_BP=353
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSC
ISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQD
KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMV
EGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRD
CEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSG
YPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTES

--------------------------------------------------------------
>12503_12503_4_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000457584_length(transcript)=2130nt_BP=1109nt
CAGGCGGGACGGGCTCTCCCTTGGGTGCTTAGCCCCGCCCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCT
GGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACA
GTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTG
GCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTA
AACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCC
GGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACTCAGGGAGAGGTGGAAGAGATTGAGC
AGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAGCAGAACTCAGACATGCAGGCTGAGC
TCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTATTGGGAGA
CAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAGGCCCAGC
TGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAAAATGACC
ACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACTACTGCAA
TGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTGCAGAGAC
AGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGA
TGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGAGAGCTCC
GGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTG
GCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAGGGCCAGA
GCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGG
ATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTCTTCTCAG
GAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATC
AGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACGGACGGGC
CTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTC
TCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCA
CGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGA

>12503_12503_4_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000457584_length(amino acids)=687AA_BP=353
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSC
ISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQD
KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMV
EGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRD
CEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSG
YPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTES

--------------------------------------------------------------
>12503_12503_5_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000534050_length(transcript)=2130nt_BP=1109nt
CAGGCGGGACGGGCTCTCCCTTGGGTGCTTAGCCCCGCCCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCT
GGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACA
GTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTG
GCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTA
AACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCC
GGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACTCAGGGAGAGGTGGAAGAGATTGAGC
AGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAGCAGAACTCAGACATGCAGGCTGAGC
TCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTATTGGGAGA
CAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAGGCCCAGC
TGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAAAATGACC
ACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACTACTGCAA
TGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTGCAGAGAC
AGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTATTCTCTGA
TGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGAGAGCTCC
GGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTG
GCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAGGGCCAGA
GCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTATGCCTGGG
ATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTCTTCTCAG
GAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACCACCAATC
AGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACGGACGGGC
CTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGCCTGCCTC
TCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCA
CGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAGGGCGAGA

>12503_12503_5_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000258947_WRAP53_chr17_7604059_ENST00000534050_length(amino acids)=687AA_BP=353
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEVEEIEQHNKELCKENQELKDSC
ISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQD
KTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMV
EGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRD
CEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSG
YPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTES

--------------------------------------------------------------
>12503_12503_6_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000316024_length(transcript)=1957nt_BP=936nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCT
GTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTAT
ACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTC
ATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGAT
GAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGAC
ATCCTGGTTGTTACCACTCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTAT
TGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAG
GCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAA
AATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACT
ACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTG
CAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTAT
TCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGA
GAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTC
TTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAG
GGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTAT
GCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACC
ACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACG
GACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGC
CTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTG
CTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAG

>12503_12503_6_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000316024_length(amino acids)=645AA_BP=311
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQEELETLQSINKKLELKVKEQKDYW
ETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETT
AMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGE
LRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYA
WDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTD
GPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQG

--------------------------------------------------------------
>12503_12503_7_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000396463_length(transcript)=1957nt_BP=936nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCT
GTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTAT
ACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTC
ATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGAT
GAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGAC
ATCCTGGTTGTTACCACTCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTAT
TGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAG
GCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAA
AATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACT
ACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTG
CAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTAT
TCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGA
GAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTC
TTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAG
GGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTAT
GCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACC
ACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACG
GACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGC
CTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTG
CTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAG

>12503_12503_7_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000396463_length(amino acids)=645AA_BP=311
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQEELETLQSINKKLELKVKEQKDYW
ETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETT
AMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGE
LRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYA
WDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTD
GPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQG

--------------------------------------------------------------
>12503_12503_8_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000431639_length(transcript)=1957nt_BP=936nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCT
GTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTAT
ACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTC
ATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGAT
GAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGAC
ATCCTGGTTGTTACCACTCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTAT
TGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAG
GCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAA
AATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACT
ACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTG
CAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTAT
TCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGA
GAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTC
TTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAG
GGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTAT
GCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACC
ACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACG
GACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGC
CTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTG
CTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAG

>12503_12503_8_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000431639_length(amino acids)=645AA_BP=311
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQEELETLQSINKKLELKVKEQKDYW
ETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETT
AMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGE
LRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYA
WDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTD
GPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQG

--------------------------------------------------------------
>12503_12503_9_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000457584_length(transcript)=1957nt_BP=936nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCT
GTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTAT
ACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTC
ATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGAT
GAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGAC
ATCCTGGTTGTTACCACTCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTAT
TGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAG
GCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAA
AATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACT
ACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTG
CAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTAT
TCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGA
GAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTC
TTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAG
GGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTAT
GCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACC
ACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACG
GACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGC
CTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTG
CTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAG

>12503_12503_9_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000457584_length(amino acids)=645AA_BP=311
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQEELETLQSINKKLELKVKEQKDYW
ETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETT
AMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGE
LRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYA
WDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTD
GPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQG

--------------------------------------------------------------
>12503_12503_10_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000534050_length(transcript)=1957nt_BP=936nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGCT
GTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTAT
ACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTC
ATGTGGGTTACTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGAT
GAGTATTACCAGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGAC
ATCCTGGTTGTTACCACTCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTGAAAGAACAGAAGGACTAT
TGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATCAGAGTGGATCAGCTTCAG
GCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTAGAGCAGCTGAAAAAGGAA
AATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAAATGAAGCAGAATGAAACT
ACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAAATTATATGTAATGCTCTG
CAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATCTATGATTACTGCTGGTAT
TCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATCTGGGACGCATTCACTGGA
GAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCCCCGGATGGCTCCCAGCTC
TTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCCACATTTGCAAAAAAGCAG
GGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGCCGCTCCCTGGGTCTGTAT
GCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCATCCCGATGGCAACCGCTTC
TTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCCCTGGGTCGAGAGGTGACC
ACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCTGTCTCTGTGTGGGACACG
GACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGCGTGAGCCTGCACCCTAGC
CTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAGGAGCTGGGCCTTCCCTTG
CTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGCATCCCTGATGATCACCAG

>12503_12503_10_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000416445_WRAP53_chr17_7604059_ENST00000534050_length(amino acids)=645AA_BP=311
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRVGWKTTREYYTFM
WVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQEELETLQSINKKLELKVKEQKDYW
ETELLQLKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETT
AMKKQQELMDENFDLSKRLSENEIICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGE
LRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYA
WDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTD
GPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQG

--------------------------------------------------------------
>12503_12503_11_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000316024_length(transcript)=2156nt_BP=1135nt
CACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGC
TGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTA
TACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGCATTTAAATGTTTCCAAGACAAATTGGAACAAGA
ACTACTCAAATGGAGGAGCCAAGGACAGAAATTGCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCC
CATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTG
CTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCAC
TCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAA
GCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGT
GAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAAT
CAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTT
AGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCA
AATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGA
AATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCAT
CTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATAT
CTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTC
CCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGC
CACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGG
CCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCA
TCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTC
CCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGC
TGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGG
CGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGA
GGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAG

>12503_12503_11_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000316024_length(amino acids)=711AA_BP=377
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRAFKCFQDKLEQEL
LKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQ
GEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIR
VDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEI
ICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSP
DGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHP
DGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGV

--------------------------------------------------------------
>12503_12503_12_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000396463_length(transcript)=2156nt_BP=1135nt
CACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGC
TGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTA
TACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGCATTTAAATGTTTCCAAGACAAATTGGAACAAGA
ACTACTCAAATGGAGGAGCCAAGGACAGAAATTGCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCC
CATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTG
CTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCAC
TCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAA
GCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGT
GAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAAT
CAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTT
AGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCA
AATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGA
AATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCAT
CTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATAT
CTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTC
CCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGC
CACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGG
CCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCA
TCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTC
CCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGC
TGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGG
CGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGA
GGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAG

>12503_12503_12_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000396463_length(amino acids)=711AA_BP=377
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRAFKCFQDKLEQEL
LKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQ
GEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIR
VDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEI
ICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSP
DGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHP
DGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGV

--------------------------------------------------------------
>12503_12503_13_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000431639_length(transcript)=2156nt_BP=1135nt
CACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGC
TGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTA
TACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGCATTTAAATGTTTCCAAGACAAATTGGAACAAGA
ACTACTCAAATGGAGGAGCCAAGGACAGAAATTGCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCC
CATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTG
CTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCAC
TCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAA
GCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGT
GAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAAT
CAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTT
AGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCA
AATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGA
AATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCAT
CTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATAT
CTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTC
CCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGC
CACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGG
CCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCA
TCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTC
CCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGC
TGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGG
CGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGA
GGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAG

>12503_12503_13_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000431639_length(amino acids)=711AA_BP=377
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRAFKCFQDKLEQEL
LKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQ
GEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIR
VDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEI
ICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSP
DGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHP
DGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGV

--------------------------------------------------------------
>12503_12503_14_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000457584_length(transcript)=2156nt_BP=1135nt
CACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGC
TGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTA
TACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGCATTTAAATGTTTCCAAGACAAATTGGAACAAGA
ACTACTCAAATGGAGGAGCCAAGGACAGAAATTGCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCC
CATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTG
CTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCAC
TCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAA
GCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGT
GAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAAT
CAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTT
AGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCA
AATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGA
AATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCAT
CTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATAT
CTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTC
CCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGC
CACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGG
CCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCA
TCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTC
CCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGC
TGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGG
CGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGA
GGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAG

>12503_12503_14_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000457584_length(amino acids)=711AA_BP=377
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRAFKCFQDKLEQEL
LKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQ
GEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIR
VDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEI
ICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSP
DGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHP
DGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGV

--------------------------------------------------------------
>12503_12503_15_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000534050_length(transcript)=2156nt_BP=1135nt
CACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCCACATCAGC
TGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACATGTCATTA
TACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGAGCATTTAAATGTTTCCAAGACAAATTGGAACAAGA
ACTACTCAAATGGAGGAGCCAAGGACAGAAATTGCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCC
CATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTG
CTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCAC
TCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAA
GCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGT
GAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAAT
CAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTT
AGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCA
AATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGA
AATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCAT
CTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATAT
CTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTC
CCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGC
CACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGG
CCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCA
TCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTC
CCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGC
TGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGG
CGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGA
GGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAG

>12503_12503_15_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000448105_WRAP53_chr17_7604059_ENST00000534050_length(amino acids)=711AA_BP=377
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRAFKCFQDKLEQEL
LKWRSQGQKLQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQ
GEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIR
VDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEI
ICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSP
DGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHP
DGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGV

--------------------------------------------------------------
>12503_12503_16_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000316024_length(transcript)=1893nt_BP=872nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTA
CTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACC
AGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTG
TTACCACTCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCC
TCCAGAAGCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAAC
TGAAAGTGAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGA
TGGGAATCAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAG
AGCAGTTAGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAG
TGGAGCAAATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTG
AGAACGAAATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTG
ATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGA
TTCATATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCT
GCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGG
TCCGAGCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCT
CCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCT
GCTTTCATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCAC
TGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGA
GCGGGGCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCA
CCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACG
AAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAG
ACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATG

>12503_12503_16_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000316024_length(amino acids)=622AA_BP=288
MLLSRRCWLLSLVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTT
QGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGI
RVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENE
IICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFS
PDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFH
PDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNG

--------------------------------------------------------------
>12503_12503_17_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000396463_length(transcript)=1893nt_BP=872nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTA
CTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACC
AGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTG
TTACCACTCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCC
TCCAGAAGCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAAC
TGAAAGTGAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGA
TGGGAATCAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAG
AGCAGTTAGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAG
TGGAGCAAATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTG
AGAACGAAATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTG
ATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGA
TTCATATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCT
GCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGG
TCCGAGCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCT
CCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCT
GCTTTCATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCAC
TGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGA
GCGGGGCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCA
CCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACG
AAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAG
ACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATG

>12503_12503_17_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000396463_length(amino acids)=622AA_BP=288
MLLSRRCWLLSLVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTT
QGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGI
RVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENE
IICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFS
PDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFH
PDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNG

--------------------------------------------------------------
>12503_12503_18_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000431639_length(transcript)=1893nt_BP=872nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTA
CTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACC
AGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTG
TTACCACTCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCC
TCCAGAAGCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAAC
TGAAAGTGAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGA
TGGGAATCAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAG
AGCAGTTAGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAG
TGGAGCAAATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTG
AGAACGAAATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTG
ATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGA
TTCATATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCT
GCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGG
TCCGAGCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCT
CCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCT
GCTTTCATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCAC
TGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGA
GCGGGGCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCA
CCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACG
AAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAG
ACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATG

>12503_12503_18_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000431639_length(amino acids)=622AA_BP=288
MLLSRRCWLLSLVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTT
QGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGI
RVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENE
IICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFS
PDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFH
PDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNG

--------------------------------------------------------------
>12503_12503_19_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000457584_length(transcript)=1893nt_BP=872nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTA
CTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACC
AGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTG
TTACCACTCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCC
TCCAGAAGCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAAC
TGAAAGTGAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGA
TGGGAATCAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAG
AGCAGTTAGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAG
TGGAGCAAATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTG
AGAACGAAATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTG
ATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGA
TTCATATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCT
GCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGG
TCCGAGCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCT
CCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCT
GCTTTCATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCAC
TGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGA
GCGGGGCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCA
CCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACG
AAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAG
ACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATG

>12503_12503_19_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000457584_length(amino acids)=622AA_BP=288
MLLSRRCWLLSLVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTT
QGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGI
RVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENE
IICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFS
PDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFH
PDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNG

--------------------------------------------------------------
>12503_12503_20_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000534050_length(transcript)=1893nt_BP=872nt
ACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTA
CTTTGCCCATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACC
AGTTCTGCTATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTG
TTACCACTCAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCC
TCCAGAAGCAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAAC
TGAAAGTGAAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGA
TGGGAATCAGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAG
AGCAGTTAGAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAG
TGGAGCAAATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTG
AGAACGAAATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTG
ATACCATCTATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGA
TTCATATCTGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCT
GCTTCTCCCCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGG
TCCGAGCCACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCT
CCTACGGCCGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCT
GCTTTCATCCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCAC
TGTGGTCCCTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGA
GCGGGGCTGTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCA
CCAATGGCGTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACG
AAGGAGAGGAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAG
ACTCCAGCATCCCTGATGATCACCAGGGCGAGAAAGGGCAGGGAGGAACGGAGGGAGGTGTGGGTGAGCTGATATAAAAAGGTTTTTATG

>12503_12503_20_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000508679_WRAP53_chr17_7604059_ENST00000534050_length(amino acids)=622AA_BP=288
MLLSRRCWLLSLVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTT
QGEVEEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGI
RVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENE
IICNALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFS
PDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFH
PDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNG

--------------------------------------------------------------
>12503_12503_21_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000316024_length(transcript)=2155nt_BP=1134nt
CCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCC
ACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACA
TGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGATGTAGTCTTAATCAGACTATTCAACTC
CTCATCACCCCAGACACTGGTAGTATCTGGCACCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCC
ATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGC
TATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACT
CAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAG
CAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTG
AAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATC
AGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTA
GAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAA
ATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAA
ATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATC
TGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCC
CCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCC
ACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGC
CGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCAT
CCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCC
CTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCT
GTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGC
GTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAG
GAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGC

>12503_12503_21_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000316024_length(amino acids)=708AA_BP=374
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRCSLNQTIQLLITP
DTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEV
EEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQ
LQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICN
ALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGS
QLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGN
RFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLH

--------------------------------------------------------------
>12503_12503_22_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000396463_length(transcript)=2155nt_BP=1134nt
CCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCC
ACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACA
TGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGATGTAGTCTTAATCAGACTATTCAACTC
CTCATCACCCCAGACACTGGTAGTATCTGGCACCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCC
ATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGC
TATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACT
CAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAG
CAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTG
AAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATC
AGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTA
GAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAA
ATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAA
ATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATC
TGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCC
CCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCC
ACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGC
CGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCAT
CCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCC
CTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCT
GTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGC
GTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAG
GAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGC

>12503_12503_22_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000396463_length(amino acids)=708AA_BP=374
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRCSLNQTIQLLITP
DTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEV
EEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQ
LQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICN
ALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGS
QLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGN
RFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLH

--------------------------------------------------------------
>12503_12503_23_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000431639_length(transcript)=2155nt_BP=1134nt
CCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCC
ACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACA
TGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGATGTAGTCTTAATCAGACTATTCAACTC
CTCATCACCCCAGACACTGGTAGTATCTGGCACCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCC
ATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGC
TATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACT
CAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAG
CAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTG
AAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATC
AGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTA
GAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAA
ATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAA
ATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATC
TGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCC
CCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCC
ACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGC
CGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCAT
CCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCC
CTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCT
GTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGC
GTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAG
GAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGC

>12503_12503_23_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000431639_length(amino acids)=708AA_BP=374
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRCSLNQTIQLLITP
DTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEV
EEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQ
LQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICN
ALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGS
QLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGN
RFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLH

--------------------------------------------------------------
>12503_12503_24_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000457584_length(transcript)=2155nt_BP=1134nt
CCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCC
ACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACA
TGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGATGTAGTCTTAATCAGACTATTCAACTC
CTCATCACCCCAGACACTGGTAGTATCTGGCACCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCC
ATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGC
TATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACT
CAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAG
CAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTG
AAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATC
AGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTA
GAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAA
ATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAA
ATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATC
TGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCC
CCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCC
ACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGC
CGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCAT
CCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCC
CTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCT
GTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGC
GTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAG
GAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGC

>12503_12503_24_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000457584_length(amino acids)=708AA_BP=374
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRCSLNQTIQLLITP
DTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEV
EEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQ
LQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICN
ALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGS
QLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGN
RFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLH

--------------------------------------------------------------
>12503_12503_25_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000534050_length(transcript)=2155nt_BP=1134nt
CCCCGTCCCACTCTGCCCTGTTGCTGTCGCGCCGCTGCTGGTTGCTGTCCCTGGACCCCTACCATGGAGGAGACCATCAAAGATCCCCCC
ACATCAGCTGTCTTGCTGGATCACTGTCATTTCTCTCAGGTCATCTTTAACAGTGTGGAGAAGTTCTACATCCCTGGAGGGGACGTCACA
TGTCATTATACCTTCACCCAGCATTTCATCCCTCGTCGAAAGGATTGGATTGGCATCTTTAGATGTAGTCTTAATCAGACTATTCAACTC
CTCATCACCCCAGACACTGGTAGTATCTGGCACCAGGTGGGGTGGAAGACAACCCGTGAGTATTACACCTTCATGTGGGTTACTTTGCCC
ATTGACCTAAACAACAAATCAGCTAAACAGCAGGAAGTCCAATTCAAAGCTTACTACCTGCCCAAGGATGATGAGTATTACCAGTTCTGC
TATGTGGATGAGGATGGTGTGGTCCGGGGAGCAAGTATTCCTTTCCAATTCCGTCCAGAAAATGAGGAAGACATCCTGGTTGTTACCACT
CAGGGAGAGGTGGAAGAGATTGAGCAGCACAACAAGGAGCTTTGCAAAGAAAACCAGGAGCTGAAGGACAGCTGTATCAGCCTCCAGAAG
CAGAACTCAGACATGCAGGCTGAGCTCCAAAAGAAGCAGGAGGAGCTAGAAACCCTACAGAGCATCAATAAGAAGTTGGAACTGAAAGTG
AAAGAACAGAAGGACTATTGGGAGACAGAGCTGCTTCAACTGAAAGAACAAAACCAGAAGATGTCCTCAGAAAATGAGAAGATGGGAATC
AGAGTGGATCAGCTTCAGGCCCAGCTGTCAACTCAAGAGAAAGAAATGGAGAAGCTTGTTCAGGGAGATCAAGATAAGACAGAGCAGTTA
GAGCAGCTGAAAAAGGAAAATGACCACCTCTTTCTCAGTTTAACTGAACAGAGGAAGGACCAGAAGAAGCTCGAGCAGACAGTGGAGCAA
ATGAAGCAGAATGAAACTACTGCAATGAAGAAACAACAGGAATTAATGGATGAAAACTTTGACCTGTCAAAAAGACTGAGTGAGAACGAA
ATTATATGTAATGCTCTGCAGAGACAGAAAGAGAGATTGGAAGGAGAAAATGATGTCCCTGTCCTTCGAATGGTGGAAGGTGATACCATC
TATGATTACTGCTGGTATTCTCTGATGTCCTCAGCCCAGCCAGACACCTCCTACGTGGCCAGCAGCAGCCGGGAGAACCCGATTCATATC
TGGGACGCATTCACTGGAGAGCTCCGGGCTTCCTTTCGCGCCTACAACCACCTGGATGAGCTGACGGCAGCCCATTCGCTCTGCTTCTCC
CCGGATGGCTCCCAGCTCTTCTGTGGCTTCAACCGGACTGTGCGTGTTTTTTCCACGGCCCGGCCTGGCCGAGACTGCGAGGTCCGAGCC
ACATTTGCAAAAAAGCAGGGCCAGAGCGGCATCATCTCCTGCATAGCCTTCAGCCCAGCCCAGCCCCTCTATGCCTGTGGCTCCTACGGC
CGCTCCCTGGGTCTGTATGCCTGGGATGATGGCTCCCCTCTCGCCTTGCTGGGAGGGCACCAAGGGGGCATCACCCACCTCTGCTTTCAT
CCCGATGGCAACCGCTTCTTCTCAGGAGCCCGCAAGGATGCTGAGCTCCTGTGCTGGGATCTCCGGCAGTCTGGTTACCCACTGTGGTCC
CTGGGTCGAGAGGTGACCACCAATCAGCGCATCTACTTCGATCTGGACCCGACCGGGCAGTTCCTAGTGAGTGGCAGCACGAGCGGGGCT
GTCTCTGTGTGGGACACGGACGGGCCTGGCAATGATGGGAAGCCGGAGCCCGTGTTGAGTTTTCTGCCCCAGAAGGACTGCACCAATGGC
GTGAGCCTGCACCCTAGCCTGCCTCTCCTGGCCACTGCCTCCGGTCAGCGTGTGTTTCCTGAGCCCACAGAGAGTGGGGACGAAGGAGAG
GAGCTGGGCCTTCCCTTGCTCTCCACGCGCCACGTCCACCTTGAATGTCGGCTTCAGCTCTGGTGGTGTGGGGGGGCGCCAGACTCCAGC

>12503_12503_25_CALCOCO2-WRAP53_CALCOCO2_chr17_46933549_ENST00000509507_WRAP53_chr17_7604059_ENST00000534050_length(amino acids)=708AA_BP=374
MPCCCRAAAGCCPWTPTMEETIKDPPTSAVLLDHCHFSQVIFNSVEKFYIPGGDVTCHYTFTQHFIPRRKDWIGIFRCSLNQTIQLLITP
DTGSIWHQVGWKTTREYYTFMWVTLPIDLNNKSAKQQEVQFKAYYLPKDDEYYQFCYVDEDGVVRGASIPFQFRPENEEDILVVTTQGEV
EEIEQHNKELCKENQELKDSCISLQKQNSDMQAELQKKQEELETLQSINKKLELKVKEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQ
LQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICN
ALQRQKERLEGENDVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGS
QLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGN
RFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CALCOCO2-WRAP53

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000258947	+	10	13	371_381	336.0	447.0	LGALS8
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000416445	+	9	12	371_381	294.0	405.0	LGALS8
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000448105	+	11	14	371_381	360.0	471.0	LGALS8
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000508679	+	9	12	371_381	264.0	375.0	LGALS8
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000509507	+	11	14	371_381	357.0	468.0	LGALS8
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000258947	+	10	13	395_446	336.0	447.0	MYO6
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000416445	+	9	12	395_446	294.0	405.0	MYO6
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000448105	+	11	14	395_446	360.0	471.0	MYO6
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000508679	+	9	12	395_446	264.0	375.0	MYO6
Hgene	CALCOCO2	chr17:46933549	chr17:7604059	ENST00000509507	+	11	14	395_446	357.0	468.0	MYO6

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for CALCOCO2-WRAP53

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CALCOCO2-WRAP53

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CALCOCO2	C0009402	Colorectal Carcinoma	1	CTD_human
Hgene	CALCOCO2	C0009404	Colorectal Neoplasms	1	CTD_human
Tgene		C0265965	Dyskeratosis Congenita	5	CLINGEN;GENOMICS_ENGLAND
Tgene		C3151442	DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3	3	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene		C0005910	Body Weight	1	CTD_human
Tgene		C1845987	Neutropenia, Severe Congenital, X-Linked	1	GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:CALCOCO2-WRAP53 (FusionGDB2 ID:HG10241TG55135)

Fusion Gene Summary for CALCOCO2-WRAP53

Fusion Gene ORF analysis for CALCOCO2-WRAP53

Fusion Genomic Features for CALCOCO2-WRAP53

Fusion Protein Features for CALCOCO2-WRAP53

Fusion Gene Sequence for CALCOCO2-WRAP53

Fusion Gene PPI Analysis for CALCOCO2-WRAP53

Related Drugs for CALCOCO2-WRAP53

Related Diseases for CALCOCO2-WRAP53

Fusion Gene Studies
in Kim Lab