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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CDKN2A-SRGAP2 (FusionGDB2 ID:HG1029TG23380)

Fusion Gene Summary for CDKN2A-SRGAP2

Fusion gene summary

Fusion gene information	Fusion gene name: CDKN2A-SRGAP2
	Fusion gene ID: hg1029tg23380
		Hgene	Tgene
	Gene symbol	CDKN2A	SRGAP2
	Gene ID	1029	23380
	Gene name	cyclin dependent kinase inhibitor 2A	SLIT-ROBO Rho GTPase activating protein 2
	Synonyms	ARF\|CDK4I\|CDKN2\|CMM2\|INK4\|INK4A\|MLM\|MTS-1\|MTS1\|P14\|P14ARF\|P16\|P16-INK4A\|P16INK4\|P16INK4A\|P19\|P19ARF\|TP16	ARHGAP34\|FNBP2\|SRGAP2A\|SRGAP3
	Cytomap	('CDKN2A')('SRGAP2') 9p21.3	1q32.1
	Type of gene	protein-coding	protein-coding
	Description	cyclin-dependent kinase inhibitor 2ACDK4 inhibitor p16-INK4alternative reading framecell cycle negative regulator betacyclin-dependent kinase 4 inhibitor Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)multiple tumor suppressor 1	SLIT-ROBO Rho GTPase-activating protein 2SLIT-ROBO GAP2formin-binding protein 2rho GTPase-activating protein 34
	Modification date	20200329	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000304494, ENST00000361570, ENST00000446177, ENST00000498124, ENST00000530628, ENST00000579122, ENST00000579755, ENST00000470819, ENST00000479692, ENST00000494262, ENST00000497750, ENST00000498628, ENST00000578845,
Fusion gene scores	* DoF score	14 X 9 X 11=1386	15 X 15 X 7=1575
	# samples	17	16
	** MAII score	log2(17/1386*10)=-3.02732060599951 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/1575*10)=-3.29920801838728 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CDKN2A [Title/Abstract] AND SRGAP2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CDKN2A(21994138)-SRGAP2(206634382), # samples:3
Anticipated loss of major functional domain due to fusion event.	CDKN2A-SRGAP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CDKN2A-SRGAP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CDKN2A-SRGAP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CDKN2A-SRGAP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CDKN2A	GO:0000082	G1/S transition of mitotic cell cycle	10208428
Hgene	CDKN2A	GO:0007050	cell cycle arrest	15149599
Hgene	CDKN2A	GO:0008285	negative regulation of cell proliferation	15149599
Hgene	CDKN2A	GO:0030308	negative regulation of cell growth	10208428
Hgene	CDKN2A	GO:0032088	negative regulation of NF-kappaB transcription factor activity	10353611
Hgene	CDKN2A	GO:0042326	negative regulation of phosphorylation	8259215\|10208428
Hgene	CDKN2A	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	7739547\|8259215
Tgene	SRGAP2	GO:0043547	positive regulation of GTPase activity	21148482
Tgene	SRGAP2	GO:0046847	filopodium assembly	22559944
Tgene	SRGAP2	GO:0051014	actin filament severing	21148482
Tgene	SRGAP2	GO:0060996	dendritic spine development	22559944
Tgene	SRGAP2	GO:2001223	negative regulation of neuron migration	22559944

Fusion gene breakpoints across CDKN2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SRGAP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUSC	TCGA-60-2715-01A	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
ChimerDB4	LUSC	TCGA-60-2715	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
ChimerDB4	LUSC	TCGA-60-2715	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
ChimerDB4	LUSC	TCGA-60-2715	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+

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Fusion Gene ORF analysis for CDKN2A-SRGAP2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000304494	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000304494	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000304494	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000304494	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000361570	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000361570	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000446177	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000446177	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000446177	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000446177	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000498124	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000498124	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000498124	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000498124	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000530628	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000530628	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000579122	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000579122	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000579122	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
5CDS-intron	ENST00000579122	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000579755	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
5CDS-intron	ENST00000579755	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000304494	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
In-frame	ENST00000304494	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000361570	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000446177	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
In-frame	ENST00000446177	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000498124	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
In-frame	ENST00000498124	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000530628	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000579122	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
In-frame	ENST00000579122	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
In-frame	ENST00000579755	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000304494	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000361570	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000361570	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000446177	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000470819	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000470819	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000470819	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000479692	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000479692	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000479692	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000494262	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000494262	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000494262	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000497750	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000497750	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000497750	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000498124	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000498628	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000498628	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000498628	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000530628	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000530628	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000578845	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000578845	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000578845	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000579122	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-3CDS	ENST00000579755	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-3CDS	ENST00000579755	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000304494	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000304494	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000361570	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000361570	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000361570	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000361570	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000446177	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000446177	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000470819	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000470819	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000470819	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000470819	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000470819	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000470819	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000479692	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000479692	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000479692	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000479692	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000479692	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000479692	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000494262	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000494262	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000494262	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000494262	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000494262	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000494262	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000497750	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000497750	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000497750	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000497750	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000497750	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000497750	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498124	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498124	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498628	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498628	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000498628	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498628	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000498628	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000498628	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000530628	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000530628	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000530628	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000530628	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000578845	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000578845	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000578845	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000578845	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000578845	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000578845	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000579122	ENST00000419187	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000579122	ENST00000471256	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000579755	ENST00000419187	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000579755	ENST00000419187	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+
intron-intron	ENST00000579755	ENST00000471256	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+
intron-intron	ENST00000579755	ENST00000471256	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000361570	CDKN2A	chr9	21994138	-	ENST00000414007	SRGAP2	chr1	206634382	+	3755	353	720	322	132
ENST00000579755	CDKN2A	chr9	21994138	-	ENST00000414007	SRGAP2	chr1	206634382	+	3888	486	853	455	132
ENST00000530628	CDKN2A	chr9	21994138	-	ENST00000414007	SRGAP2	chr1	206634382	+	3675	273	640	242	132
ENST00000304494	CDKN2A	chr9	21974676	-	ENST00000414007	SRGAP2	chr1	206634381	+	3823	421	124	804	226
ENST00000579122	CDKN2A	chr9	21974676	-	ENST00000414007	SRGAP2	chr1	206634381	+	3583	181	31	564	177
ENST00000498124	CDKN2A	chr9	21974676	-	ENST00000414007	SRGAP2	chr1	206634381	+	3591	189	39	572	177
ENST00000446177	CDKN2A	chr9	21974676	-	ENST00000414007	SRGAP2	chr1	206634381	+	3764	362	65	745	226
ENST00000304494	CDKN2A	chr9	21974677	-	ENST00000414007	SRGAP2	chr1	206634382	+	3823	421	124	804	226
ENST00000579122	CDKN2A	chr9	21974677	-	ENST00000414007	SRGAP2	chr1	206634382	+	3583	181	31	564	177
ENST00000498124	CDKN2A	chr9	21974677	-	ENST00000414007	SRGAP2	chr1	206634382	+	3591	189	39	572	177
ENST00000446177	CDKN2A	chr9	21974677	-	ENST00000414007	SRGAP2	chr1	206634382	+	3764	362	65	745	226

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000361570	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+	0.0794019	0.92059815
ENST00000579755	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+	0.08829938	0.91170055
ENST00000530628	ENST00000414007	CDKN2A	chr9	21994138	-	SRGAP2	chr1	206634382	+	0.079666264	0.9203337
ENST00000304494	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	0.011213584	0.98878646
ENST00000579122	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	0.009223487	0.9907766
ENST00000498124	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	0.009401987	0.990598
ENST00000446177	ENST00000414007	CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	0.01064239	0.98935765
ENST00000304494	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+	0.011213584	0.98878646
ENST00000579122	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+	0.009223487	0.9907766
ENST00000498124	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+	0.009401987	0.990598
ENST00000446177	ENST00000414007	CDKN2A	chr9	21974677	-	SRGAP2	chr1	206634382	+	0.01064239	0.98935765

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Fusion Genomic Features for CDKN2A-SRGAP2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
CDKN2A	chr9	21994137	-	SRGAP2	chr1	206634381	+	1.34E-09	1
CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	1.71E-10	1
CDKN2A	chr9	21994137	-	SRGAP2	chr1	206634381	+	1.34E-09	1
CDKN2A	chr9	21994137	-	SRGAP2	chr1	206634381	+	1.34E-09	1
CDKN2A	chr9	21974676	-	SRGAP2	chr1	206634381	+	1.71E-10	1
CDKN2A	chr9	21994137	-	SRGAP2	chr1	206634381	+	1.34E-09	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CDKN2A-SRGAP2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:21994138/chr1:206634382)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000304494

11_40

157.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000446177

11_40

168.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498124

11_40

130.66666666666666

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000304494

11_40

157.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000446177

11_40

168.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498124

11_40

130.66666666666666

Repeat

Note=ANK 1

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000304494

110_139

157.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000304494

44_72

157.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000304494

77_106

157.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000446177

110_139

168.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000446177

44_72

168.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000446177

77_106

168.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000494262

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000494262

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000494262

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000494262

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498124

110_139

130.66666666666666

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498124

44_72

130.66666666666666

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498124

77_106

130.66666666666666

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498628

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498628

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498628

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000498628

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000578845

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000578845

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000578845

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974676

chr1:206634381

ENST00000578845

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000304494

110_139

157.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000304494

44_72

157.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000304494

77_106

157.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000446177

110_139

168.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000446177

44_72

168.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000446177

77_106

168.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000494262

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000494262

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000494262

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000494262

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498124

110_139

130.66666666666666

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498124

44_72

130.66666666666666

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498124

77_106

130.66666666666666

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498628

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498628

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498628

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000498628

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000578845

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000578845

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000578845

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21974677

chr1:206634382

ENST00000578845

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000304494

110_139

157.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000304494

11_40

157.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000304494

44_72

157.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000304494

77_106

157.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000446177

110_139

168.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000446177

11_40

168.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000446177

44_72

168.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000446177

77_106

168.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000494262

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000494262

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000494262

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000494262

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498124

110_139

130.66666666666666

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498124

11_40

130.66666666666666

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498124

44_72

130.66666666666666

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498124

77_106

130.66666666666666

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498628

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498628

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498628

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000498628

77_106

106.0

Repeat

Note=ANK 3

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000578845

110_139

106.0

Repeat

Note=ANK 4

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000578845

11_40

106.0

Repeat

Note=ANK 1

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000578845

44_72

106.0

Repeat

Note=ANK 2

Hgene

CDKN2A

chr9:21994138

chr1:206634382

ENST00000578845

77_106

106.0

Repeat

Note=ANK 3

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Fusion Gene Sequence for CDKN2A-SRGAP2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>15413_15413_1_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000304494_SRGAP2_chr1_206634381_ENST00000414007_length(transcript)=3823nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGGATATTGAGGCAACAATGAACTCGGCCCT
GAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTCTGGACACCTTGGAGCCCCTCAAAACCTCCCC
AGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCCCGAGCCCGCCTTCCAGCGCAGCGCCAGTAC
TGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGTCAAACCACCAGCCACACGGCCCAAGCCCAC
TGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGTCTACTGACAAGTCTTGTACTGTCTGAGGGAT
AATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCCTATTTAACTAGCTTGGGGACTTCAGTTGAAA
ATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAATGAAGCCCTTGGTATCGCCTCTCCCTTCCCA
CTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAGGTTAGCCAGAGACAGGTTTTCATTATCAGG
TCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAGACCACGGTGATGCCTTGACCAGATGGTTGG
CTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATATATAGTCCAGTCTTCATTTTACATACACACA
CATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTTCTAGTCTCTGGCATGTGTAGCCTCTCCTGGT
CATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTCTGTTTCCATTACAAACTTTGTTCTGTCTGG
GCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAATCCCGTAACCTGTTTGGGGTTGGGGGCTTTC
TCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCCATCCCCTAGAAGTACACCCCCGTCTTATTA
AGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTCTGATGGACCATTTTCCATTTAAGACATTTTC
CTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTATTGTGTCTATGGCAGGTTTGGGAAAGGTAA
GAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCCTATTAAAAAATTAAATTCAGCTTTGCTAATC
CAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTACAAGGTCTCTCTTCAGGGACCAACAGGGGCT
TAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTATGCAAACAAGGACAATTAAGGGAACCCTGACC
CCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCTGAATATTCTGGCTCTACTCTGGCCTTTTTTC
TGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAACCTGGTGCCTGTGCTCCTGGCCCCCCTAGCAT
CATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAGACAGCAACTTGAGTTAAAGCTGAAACTCATC
CTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTCTGTAGTTCCGGAGAGATGGTGGGTTGCCATT
CTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAACCTGCGAAATTGGTAGTTAGGTCTATGGAAA
GTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATCACTAATGAGAAGGCTAACCTGCAGCACCAG
AGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAGCCTAGAAGAGGCAACCCACAGTCTTGATTT
TTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCAACGGGGCTTTCATACCCAAGGATCTGTTTC
CTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAAACTGGTACCCACACTTGCCCTTTCTCCCTCT
CTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGGGCCTGTTCTGTTGCTCCTGCCTTATTTCTC
TTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTAATTTGCATCATGAACTGAACAGTGTGTGAGT
GGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTAACACCTGTGAGATGGTCCTGTCGAGAGGAC
TAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTGAGGTTGCACACTGTGATTTTTACACCGAAAA
GCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCCGAAACCAGCATGATGCTTCAAAGAGCCCTG
CTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGGGGAAGAGAGGTGGGGTGGGGCTACTAGCAT
CCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCTCAGCCAACCTCCTCAGGGCGCCCTGGCTTC
TCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGCTGGTGCAGATCTACTTCCCATGCAGAAGAG
AAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGTGTAAAATGGTATATTCTTTAAAATAGTGTTG
ATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACTCAACAGATGTTGGATTGGGGAAAATCCAAAG
CACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_1_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000304494_SRGAP2_chr1_206634381_ENST00000414007_length(amino acids)=226AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPV
KSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_2_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000446177_SRGAP2_chr1_206634381_ENST00000414007_length(transcript)=3764nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTC
TGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACC
CCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGG
TCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGT
CTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCC
TATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAA
TGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTA
GGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCA
GACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATA
TATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTT
CTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCT
CTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAA
TCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTC
CATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTC
TGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTT
ATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCC
TATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTA
CAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTAT
GCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCT
GAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAAC
CTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAG
ACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTC
TGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAA
CCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAAT
CACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCA
GCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCC
AACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAA
ACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTG
GGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTA
ATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCT
AACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTG
AGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGC
CGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCG
GGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTC
TCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGG
CTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGT
GTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACT
CAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_2_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000446177_SRGAP2_chr1_206634381_ENST00000414007_length(amino acids)=226AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPV
KSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_3_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000498124_SRGAP2_chr1_206634381_ENST00000414007_length(transcript)=3591nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGAC
GTGGTTCTGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTC
AAGGACCCCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCT
GCCCCGGTCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCC
CCACAGTCTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAA
ATCTTCCTATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACC
TTGAGAATGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACC
GTTCTTAGGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGT
CCCCTCAGACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAG
AATCATATATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATA
TGTTTTTCTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCA
GGGGTCTCTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGAT
GGGACAATCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCC
TCTCCTCCATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCT
TTGTCTCTGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGA
GAGTTTTATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTC
ATTATCCTATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCT
TATTTTACAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTT
CATTTATGCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTT
GAATGCTGAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTC
TCCAAACCTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGG
GTCTCAGACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTAT
TATTTTCTGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTT
GGACCAACCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGT
GGGAAATCACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAG
TGAGTCAGCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTC
CCGAGCCAACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACT
GATCAAAACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAA
CACTTTGGGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATC
CGCGCTAATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGG
TGCTCCTAACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACT
GGAATTGAGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTA
TGCTTGCCGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCA
GTCTTCGGGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAAC
ACTGGTCTCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACT
GGAAGGGCTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCA
CATTTGTGTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGAC
TGTCACTCAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_3_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000498124_SRGAP2_chr1_206634381_ENST00000414007_length(amino acids)=177AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSP
VVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_4_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000579122_SRGAP2_chr1_206634381_ENST00000414007_length(transcript)=3583nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTCT
GGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCC
CGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGT
CAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGTC
TACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCCT
ATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAAT
GAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAG
GTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAG
ACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATAT
ATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTTC
TAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTC
TGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAAT
CCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCC
ATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTCT
GATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTA
TTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCCT
ATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTAC
AAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTATG
CAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCTG
AATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAACC
TGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAGA
CAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTCT
GTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAAC
CTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATC
ACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAG
CCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCA
ACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAAA
CTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGG
GCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTAA
TTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTA
ACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTGA
GGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCC
GAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGG
GGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCT
CAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGC
TGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGTG
TAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACTC
AACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_4_CDKN2A-SRGAP2_CDKN2A_chr9_21974676_ENST00000579122_SRGAP2_chr1_206634381_ENST00000414007_length(amino acids)=177AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSP
VVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_5_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000304494_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3823nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGGATATTGAGGCAACAATGAACTCGGCCCT
GAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTCTGGACACCTTGGAGCCCCTCAAAACCTCCCC
AGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCCCGAGCCCGCCTTCCAGCGCAGCGCCAGTAC
TGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGTCAAACCACCAGCCACACGGCCCAAGCCCAC
TGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGTCTACTGACAAGTCTTGTACTGTCTGAGGGAT
AATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCCTATTTAACTAGCTTGGGGACTTCAGTTGAAA
ATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAATGAAGCCCTTGGTATCGCCTCTCCCTTCCCA
CTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAGGTTAGCCAGAGACAGGTTTTCATTATCAGG
TCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAGACCACGGTGATGCCTTGACCAGATGGTTGG
CTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATATATAGTCCAGTCTTCATTTTACATACACACA
CATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTTCTAGTCTCTGGCATGTGTAGCCTCTCCTGGT
CATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTCTGTTTCCATTACAAACTTTGTTCTGTCTGG
GCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAATCCCGTAACCTGTTTGGGGTTGGGGGCTTTC
TCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCCATCCCCTAGAAGTACACCCCCGTCTTATTA
AGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTCTGATGGACCATTTTCCATTTAAGACATTTTC
CTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTATTGTGTCTATGGCAGGTTTGGGAAAGGTAA
GAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCCTATTAAAAAATTAAATTCAGCTTTGCTAATC
CAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTACAAGGTCTCTCTTCAGGGACCAACAGGGGCT
TAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTATGCAAACAAGGACAATTAAGGGAACCCTGACC
CCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCTGAATATTCTGGCTCTACTCTGGCCTTTTTTC
TGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAACCTGGTGCCTGTGCTCCTGGCCCCCCTAGCAT
CATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAGACAGCAACTTGAGTTAAAGCTGAAACTCATC
CTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTCTGTAGTTCCGGAGAGATGGTGGGTTGCCATT
CTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAACCTGCGAAATTGGTAGTTAGGTCTATGGAAA
GTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATCACTAATGAGAAGGCTAACCTGCAGCACCAG
AGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAGCCTAGAAGAGGCAACCCACAGTCTTGATTT
TTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCAACGGGGCTTTCATACCCAAGGATCTGTTTC
CTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAAACTGGTACCCACACTTGCCCTTTCTCCCTCT
CTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGGGCCTGTTCTGTTGCTCCTGCCTTATTTCTC
TTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTAATTTGCATCATGAACTGAACAGTGTGTGAGT
GGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTAACACCTGTGAGATGGTCCTGTCGAGAGGAC
TAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTGAGGTTGCACACTGTGATTTTTACACCGAAAA
GCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCCGAAACCAGCATGATGCTTCAAAGAGCCCTG
CTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGGGGAAGAGAGGTGGGGTGGGGCTACTAGCAT
CCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCTCAGCCAACCTCCTCAGGGCGCCCTGGCTTC
TCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGCTGGTGCAGATCTACTTCCCATGCAGAAGAG
AAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGTGTAAAATGGTATATTCTTTAAAATAGTGTTG
ATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACTCAACAGATGTTGGATTGGGGAAAATCCAAAG
CACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_5_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000304494_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=226AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPV
KSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_6_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000446177_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3764nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTC
TGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACC
CCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGG
TCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGT
CTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCC
TATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAA
TGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTA
GGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCA
GACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATA
TATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTT
CTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCT
CTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAA
TCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTC
CATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTC
TGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTT
ATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCC
TATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTA
CAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTAT
GCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCT
GAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAAC
CTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAG
ACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTC
TGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAA
CCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAAT
CACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCA
GCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCC
AACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAA
ACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTG
GGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTA
ATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCT
AACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTG
AGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGC
CGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCG
GGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTC
TCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGG
CTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGT
GTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACT
CAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_6_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000446177_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=226AA_BP=98
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPV
KSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_7_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000498124_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3591nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGAC
GTGGTTCTGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTC
AAGGACCCCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCT
GCCCCGGTCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCC
CCACAGTCTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAA
ATCTTCCTATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACC
TTGAGAATGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACC
GTTCTTAGGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGT
CCCCTCAGACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAG
AATCATATATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATA
TGTTTTTCTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCA
GGGGTCTCTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGAT
GGGACAATCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCC
TCTCCTCCATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCT
TTGTCTCTGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGA
GAGTTTTATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTC
ATTATCCTATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCT
TATTTTACAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTT
CATTTATGCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTT
GAATGCTGAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTC
TCCAAACCTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGG
GTCTCAGACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTAT
TATTTTCTGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTT
GGACCAACCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGT
GGGAAATCACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAG
TGAGTCAGCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTC
CCGAGCCAACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACT
GATCAAAACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAA
CACTTTGGGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATC
CGCGCTAATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGG
TGCTCCTAACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACT
GGAATTGAGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTA
TGCTTGCCGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCA
GTCTTCGGGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAAC
ACTGGTCTCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACT
GGAAGGGCTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCA
CATTTGTGTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGAC
TGTCACTCAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_7_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000498124_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=177AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSP
VVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_8_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000579122_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3583nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTCT
GGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCC
CGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGT
CAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGTC
TACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCCT
ATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAAT
GAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAG
GTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAG
ACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATAT
ATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTTC
TAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTC
TGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAAT
CCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCC
ATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTCT
GATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTA
TTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCCT
ATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTAC
AAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTATG
CAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCTG
AATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAACC
TGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAGA
CAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTCT
GTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAAC
CTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATC
ACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAG
CCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCA
ACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAAA
CTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGG
GCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTAA
TTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTA
ACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTGA
GGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCC
GAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGG
GGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCT
CAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGC
TGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGTG
TAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACTC
AACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_8_CDKN2A-SRGAP2_CDKN2A_chr9_21974677_ENST00000579122_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=177AA_BP=49
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQDIEATMNSALNELRELERQSSVKHTPDVVLDTLEPLKTSP
VVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

--------------------------------------------------------------
>15413_15413_9_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000361570_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3755nt_BP=353nt
CGCTCAGGGAAGGCGGGTGCGCGCCTGCGGGGCGGAGATGGGCAGGGGGCGGTGCGTGGGTCCCAGTCTGCAGTTAAGGGGGCAGGAGTG
GCGCTGCTCACCTCTGGTGCCAAAGGGCGGCGCAGCGGCTGCCGAGCTCGGCCCTGGAGGCGGCGAGAACATGGTGCGCAGGTTCTTGGT
GACCCTCCGGATTCGGCGCGCGTGCGGCCCGCCGCGAGTGAGGGTTTTCGTGGTTCACATCCCGCGGCTCACGGGGGAGTGGGCAGCGCC
AGGGGCGCCCGCCGCTGTGGCCCTCGTGCTGATGCTACTGAGGAGCCAGCGTCTAGGGCAGCAGCCGCTTCCTAGAAGACCAGGATATTG
AGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTTCTGGACACCT
TGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCCCGAGCCCG
CCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGTCAAACCAC
CAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAGTCTACTGACA
AGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTCCTATTTAACT
AGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAATGAAGCCCT
TGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAGGTTAGCCA
GAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAGACCACGGT
GATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCATATATAGTCCA
GTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTTTCTAGTCTCT
GGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTCTGTTTCCA
TTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACAATCCCGTAAC
CTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCCATCCCCTA
GAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCTCTGATGGACC
ATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTATTGTGTCT
ATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATCCTATTAAAAA
ATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTACAAGGTCTC
TCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTATGCAAACAAG
GACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGCTGAATATTCT
GGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAACCTGGTGCCT
GTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCAGACAGCAACT
TGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTTCTGTAGTTCC
GGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCAACCTGCGAAA
TTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATCACTAATGA
GAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAGCCTAGAAG
AGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCAACGGGGCT
TTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAAAACTGGTACC
CACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGGGCCTGTTC
TGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCTAATTTGCATC
ATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTAACACCTGT
GAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATTGAGGTTGCAC
ACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCCGAAACCAG
CATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGGGGAAGAGA
GGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCTCAGCCAAC
CTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGCTGGTGCAG
ATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTGTGTAAAATGG
TATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCACTCAACAGATG
TTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_9_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000361570_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=132AA_BP=1
MSVDCGEVDELTPGLVAFVLGKTVGLGRVAGGLTGAAILTDLTGRKAQAMSPAVLALRWKAGSGSLRSWVCRGLEGSDVGATTGEVLRGS
KVSRTTSGVCLTLLCRSSSRSSFRAEFIVASISWSSRKRLLP

--------------------------------------------------------------
>15413_15413_10_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000530628_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3675nt_BP=273nt
GGCAGGAGTGGCGCTGCTCACCTCTGGTGCCAAAGGGCGGCGCAGCGGCTGCCGAGCTCGGCCCTGGAGGCGGCGAGAACATGGTGCGCA
GGTTCTTGGTGACCCTCCGGATTCGGCGCGCGTGCGGCCCGCCGCGAGTGAGGGTTTTCGTGGTTCACATCCCGCGGCTCACGGGGGAGT
GGGCAGCGCCAGGGGCGCCCGCCGCTGTGGCCCTCGTGCTGATGCTACTGAGGAGCCAGCGTCTAGGGCAGCAGCCGCTTCCTAGAAGAC
CAGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGGCAGAGCAGTGTCAAACACACCCCTGACGTGGTT
CTGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCCTCCAGCCCTCTGCACACCCAGCTCCTCAAGGAC
CCCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTCCGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCG
GTCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACTAGCCCTGGTGTCAACTCATCAACTTCCCCACAG
TCTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGGGGACTATAGGGACTGACTGTTATTAAAATCTTC
CTATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAGGAATTAGCCTCCCCGTCTCCCAAAACCTTGAGA
ATGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTCGTAATTCAGCCAGCTGCAGTCCGTACCGTTCTT
AGGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGTCCTGAGGACATGGGCTCAAGTCTCAGTCCCCTC
AGACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGCATCTTGTTTTGGGAACTGATTATAGAGAATCAT
ATATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTTACACACACACACACACACACACACATATGTTTT
TCTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTATTGTGGCAGTTCACACAGTAGCCACCAGGGGTC
TCTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATCTCTCCATCATATGAAACATAACGGGATGGGACA
ATCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTGAATTGGTCATTGGTGTTTGCTCTTGCCTCTCCT
CCATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAATGTATAGACATTTCTCGGGTTCCTACCTTTGTCT
CTGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGGTTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTT
TATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAATGTTTTTGGCACTTAAAACATAAAATTCATTATC
CTATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACTTGTTTTAAGTCCACCCCTTAGTTTCCTTATTTT
ACAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGGGAGACCCTACCTCTTAAAACCAGTTTTCATTTA
TGCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAGGCCAGAATCGAAAGAAAATTAAAATTTGAATGC
TGAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAATCATACCCTTGTCTGCTCCAATTCAGTCTCCAAA
CCTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGACCAGACACATCCACAGCCAGGCTCATGGGTCTCA
GACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTAAAAGCTGCACTTATATTTTAGCCTTATTATTTT
CTGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTTATCTTTGACCTAGAAGAGATTCTTTTTGGACCA
ACCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATCCTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAA
TCACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAGGAGAACTGAAGAACTCTTTCAGTGAAGTGAGTC
AGCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCTTGCCTGTCACCTGGGCCTACACAGGTCCCGAGC
CAACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTTTCACTTTACATTCCTTTCAATCCAACTGATCAA
AACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAAGTAAAAGCAAAGCTTTCTTAATGGCAACACTTT
GGGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGTTCACCATCCCCTTGATCAGTGTCCATCCGCGCT
AATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGGGGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCC
TAACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCTTCTCGGCAGAGCTCACTGCAAACAACTGGAATT
GAGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGGCCTAGGGAGACCAGCCTTCCTCAGCTATGCTTG
CCGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCTTTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTC
GGGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTTGTAGCCAGCAGCCTGTAAACTGGAAACACTGGT
CTCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGATGCCAGCACCGGGATGCGCAGAGCACTGGAAGG
GCTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCAATGTTGTGGCGTCTGACTTGTATGTCACATTTG
TGTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCTTGGAGATGCTTTGTGTGAACCTAAGACTGTCAC
TCAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTTTTAGGTTTCGATGCTGCA

>15413_15413_10_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000530628_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=132AA_BP=1
MSVDCGEVDELTPGLVAFVLGKTVGLGRVAGGLTGAAILTDLTGRKAQAMSPAVLALRWKAGSGSLRSWVCRGLEGSDVGATTGEVLRGS
KVSRTTSGVCLTLLCRSSSRSSFRAEFIVASISWSSRKRLLP

--------------------------------------------------------------
>15413_15413_11_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000579755_SRGAP2_chr1_206634382_ENST00000414007_length(transcript)=3888nt_BP=486nt
CGCGCGCGCCTCCCTACGGGCGCCTCCGGCAGCCCTTCCCGCGTGCGCAGGGCTCAGAGCCGTTCCGAGATCTTGGAGGTCCGGGTGGGA
GTGGGGGTGGGGTGGGGGTGGGGGTGAAGGTGGGGGGCGGGCGCGCTCAGGGAAGGCGGGTGCGCGCCTGCGGGGCGGAGATGGGCAGGG
GGCGGTGCGTGGGTCCCAGTCTGCAGTTAAGGGGGCAGGAGTGGCGCTGCTCACCTCTGGTGCCAAAGGGCGGCGCAGCGGCTGCCGAGC
TCGGCCCTGGAGGCGGCGAGAACATGGTGCGCAGGTTCTTGGTGACCCTCCGGATTCGGCGCGCGTGCGGCCCGCCGCGAGTGAGGGTTT
TCGTGGTTCACATCCCGCGGCTCACGGGGGAGTGGGCAGCGCCAGGGGCGCCCGCCGCTGTGGCCCTCGTGCTGATGCTACTGAGGAGCC
AGCGTCTAGGGCAGCAGCCGCTTCCTAGAAGACCAGGATATTGAGGCAACAATGAACTCGGCCCTGAATGAGCTACGGGAACTAGAACGG
CAGAGCAGTGTCAAACACACCCCTGACGTGGTTCTGGACACCTTGGAGCCCCTCAAAACCTCCCCAGTGGTGGCCCCCACGTCAGAGCCC
TCCAGCCCTCTGCACACCCAGCTCCTCAAGGACCCCGAGCCCGCCTTCCAGCGCAGCGCCAGTACTGCTGGGGACATCGCCTGCGCCTTC
CGGCCTGTCAAGTCTGTCAAGATGGCTGCCCCGGTCAAACCACCAGCCACACGGCCCAAGCCCACTGTCTTCCCCAAAACAAATGCCACT
AGCCCTGGTGTCAACTCATCAACTTCCCCACAGTCTACTGACAAGTCTTGTACTGTCTGAGGGATAATAATTTAATTGTTCTAGACAAGG
GGACTATAGGGACTGACTGTTATTAAAATCTTCCTATTTAACTAGCTTGGGGACTTCAGTTGAAAATTAGGTTCTAAGTTGTTCTTGCAG
GAATTAGCCTCCCCGTCTCCCAAAACCTTGAGAATGAAGCCCTTGGTATCGCCTCTCCCTTCCCACTGCCCTCTGCTTCCCCCAGTCGTC
GTAATTCAGCCAGCTGCAGTCCGTACCGTTCTTAGGTTAGCCAGAGACAGGTTTTCATTATCAGGTCACTGTGAAATCTGGTAAGGCAGT
CCTGAGGACATGGGCTCAAGTCTCAGTCCCCTCAGACCACGGTGATGCCTTGACCAGATGGTTGGCTACTGCCATCCAGCTTTCAGTGGC
ATCTTGTTTTGGGAACTGATTATAGAGAATCATATATAGTCCAGTCTTCATTTTACATACACACACATATTTTACACACACACACATTTT
ACACACACACACACACACACACACATATGTTTTTCTAGTCTCTGGCATGTGTAGCCTCTCCTGGTCATAGACCAGTCTCTTTGTAAGTTA
TTGTGGCAGTTCACACAGTAGCCACCAGGGGTCTCTGTTTCCATTACAAACTTTGTTCTGTCTGGGCCAGAGAACCTAGCCTTTGAAATC
TCTCCATCATATGAAACATAACGGGATGGGACAATCCCGTAACCTGTTTGGGGTTGGGGGCTTTCTCTCTGTGTTCTTTCCATTGATGTG
AATTGGTCATTGGTGTTTGCTCTTGCCTCTCCTCCATCCCCTAGAAGTACACCCCCGTCTTATTAAGGAGCTTTTAAAGTTTTTCTGAAT
GTATAGACATTTCTCGGGTTCCTACCTTTGTCTCTGATGGACCATTTTCCATTTAAGACATTTTCCTGTATAAGACAGTTTTATAGCTGG
TTCCTTTTAGGGTAAAGAGTCTTAAGAGAGTTTTATTGTGTCTATGGCAGGTTTGGGAAAGGTAAGAAATGGGTCCTTTTTCCTCCTAAT
GTTTTTGGCACTTAAAACATAAAATTCATTATCCTATTAAAAAATTAAATTCAGCTTTGCTAATCCAGAAATTGTTCCCAAATGAAAACT
TGTTTTAAGTCCACCCCTTAGTTTCCTTATTTTACAAGGTCTCTCTTCAGGGACCAACAGGGGCTTAGAGAGCCTTAGTTAGATTAAAGG
GAGACCCTACCTCTTAAAACCAGTTTTCATTTATGCAAACAAGGACAATTAAGGGAACCCTGACCCCACAGGCTCTCAAGTCTTCCCAAG
GCCAGAATCGAAAGAAAATTAAAATTTGAATGCTGAATATTCTGGCTCTACTCTGGCCTTTTTTCTGGTTCCCTTCCAAAATGCACAAAT
CATACCCTTGTCTGCTCCAATTCAGTCTCCAAACCTGGTGCCTGTGCTCCTGGCCCCCCTAGCATCATGCTATCCCAGGAGTATCAGGAC
CAGACACATCCACAGCCAGGCTCATGGGTCTCAGACAGCAACTTGAGTTAAAGCTGAAACTCATCCTTCTTCTCTGTGTTTTCTGGTTTA
AAAGCTGCACTTATATTTTAGCCTTATTATTTTCTGTAGTTCCGGAGAGATGGTGGGTTGCCATTCTGGTAGGAAAATCTGAGTTTTCTT
ATCTTTGACCTAGAAGAGATTCTTTTTGGACCAACCTGCGAAATTGGTAGTTAGGTCTATGGAAAGTGGTAGGATTTTTTTTTTTTAATC
CTGTGCAAAGGAAAAGAGGTGCTTTGTGGGAAATCACTAATGAGAAGGCTAACCTGCAGCACCAGAGAAACCTTTCCAAGTGCTAGGCAG
GAGAACTGAAGAACTCTTTCAGTGAAGTGAGTCAGCCTAGAAGAGGCAACCCACAGTCTTGATTTTTGTTGCTGTTTCCTGACCTGTTCT
TGCCTGTCACCTGGGCCTACACAGGTCCCGAGCCAACGGGGCTTTCATACCCAAGGATCTGTTTCCTTGCTGAAAATGAAACCCTATCTT
TCACTTTACATTCCTTTCAATCCAACTGATCAAAACTGGTACCCACACTTGCCCTTTCTCCCTCTCTCCAGCACACTCCCCTCTAAGAAA
GTAAAAGCAAAGCTTTCTTAATGGCAACACTTTGGGCCTGTTCTGTTGCTCCTGCCTTATTTCTCTTTCAACCCTGTACATGACTCGTGT
TCACCATCCCCTTGATCAGTGTCCATCCGCGCTAATTTGCATCATGAACTGAACAGTGTGTGAGTGGTCACCTACTAAACCCAGCTCTGG
GGGCAGAGCTGTCTTCCCCATCTCTGGTGCTCCTAACACCTGTGAGATGGTCCTGTCGAGAGGACTAGGAACCGATAGGAGGAGAGTCCT
TCTCGGCAGAGCTCACTGCAAACAACTGGAATTGAGGTTGCACACTGTGATTTTTACACCGAAAAGCCAAAAGGAGCTGGCCATCCAGGG
CCTAGGGAGACCAGCCTTCCTCAGCTATGCTTGCCGAAACCAGCATGATGCTTCAAAGAGCCCTGCTCCACCCCTCATGGCATGGATCCT
TTTCCTGGTGTGGACTCTGAAGGGTCAGTCTTCGGGGAAGAGAGGTGGGGTGGGGCTACTAGCATCCCAATTTAGAAAACAGAGGAGTTT
GTAGCCAGCAGCCTGTAAACTGGAAACACTGGTCTCAGCCAACCTCCTCAGGGCGCCCTGGCTTCTCCCCAAGGAGATGAGGAGCGGTGA
TGCCAGCACCGGGATGCGCAGAGCACTGGAAGGGCTGGTGCAGATCTACTTCCCATGCAGAAGAGAAGTCACATCTTCCAGGGAATCGCA
ATGTTGTGGCGTCTGACTTGTATGTCACATTTGTGTAAAATGGTATATTCTTTAAAATAGTGTTGATAACTGGAATATTGTATGTATGCT
TGGAGATGCTTTGTGTGAACCTAAGACTGTCACTCAACAGATGTTGGATTGGGGAAAATCCAAAGCACAACTTCAAAATAAAATACATTT
TTAGGTTTCGATGCTGCA

>15413_15413_11_CDKN2A-SRGAP2_CDKN2A_chr9_21994138_ENST00000579755_SRGAP2_chr1_206634382_ENST00000414007_length(amino acids)=132AA_BP=1
MSVDCGEVDELTPGLVAFVLGKTVGLGRVAGGLTGAAILTDLTGRKAQAMSPAVLALRWKAGSGSLRSWVCRGLEGSDVGATTGEVLRGS
KVSRTTSGVCLTLLCRSSSRSSFRAEFIVASISWSSRKRLLP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CDKN2A-SRGAP2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	CDKN2A	chr9:21994138	chr1:206634382	ENST00000361570	-	1	3	1_64	105.33333333333333	220.0	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21994138	chr1:206634382	ENST00000530628	-	1	3	1_64	64.33333333333333	122.66666666666667	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21994138	chr1:206634382	ENST00000579755	-	1	3	1_64	64.33333333333333	134.33333333333334	CDK5RAP3 and MDM2

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	CDKN2A	chr9:21974676	chr1:206634381	ENST00000361570	-	1	3	1_64	0	220.0	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21974676	chr1:206634381	ENST00000530628	-	1	3	1_64	0	122.66666666666667	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21974676	chr1:206634381	ENST00000579755	-	1	3	1_64	0	134.33333333333334	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21974677	chr1:206634382	ENST00000361570	-	1	3	1_64	0	220.0	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21974677	chr1:206634382	ENST00000530628	-	1	3	1_64	0	122.66666666666667	CDK5RAP3 and MDM2
Hgene	CDKN2A	chr9:21974677	chr1:206634382	ENST00000579755	-	1	3	1_64	0	134.33333333333334	CDK5RAP3 and MDM2

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CDKN2A-SRGAP2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CDKN2A-SRGAP2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	CDKN2A	C1835044	MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2	13	CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	CDKN2A	C1838547	MELANOMA-PANCREATIC CANCER SYNDROME	10	CLINGEN;CTD_human
Hgene	CDKN2A	C0024121	Lung Neoplasms	4	CTD_human;UNIPROT
Hgene	CDKN2A	C0242379	Malignant neoplasm of lung	4	CTD_human
Hgene	CDKN2A	C0011570	Mental Depression	3	PSYGENET
Hgene	CDKN2A	C0011581	Depressive disorder	3	PSYGENET
Hgene	CDKN2A	C0023903	Liver neoplasms	3	CTD_human
Hgene	CDKN2A	C0345904	Malignant neoplasm of liver	3	CTD_human
Hgene	CDKN2A	C0345967	Malignant mesothelioma	3	CTD_human
Hgene	CDKN2A	C1168401	Squamous cell carcinoma of the head and neck	3	CTD_human
Hgene	CDKN2A	C0005684	Malignant neoplasm of urinary bladder	2	CTD_human
Hgene	CDKN2A	C0005695	Bladder Neoplasm	2	CTD_human;UNIPROT
Hgene	CDKN2A	C0006118	Brain Neoplasms	2	CTD_human
Hgene	CDKN2A	C0006826	Malignant Neoplasms	2	CGI;CTD_human
Hgene	CDKN2A	C0007131	Non-Small Cell Lung Carcinoma	2	CTD_human;UNIPROT
Hgene	CDKN2A	C0017638	Glioma	2	CGI;CTD_human
Hgene	CDKN2A	C0023452	Childhood Acute Lymphoblastic Leukemia	2	CTD_human;GENOMICS_ENGLAND
Hgene	CDKN2A	C0025202	melanoma	2	CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	CDKN2A	C0027651	Neoplasms	2	CTD_human
Hgene	CDKN2A	C0030297	Pancreatic Neoplasm	2	CGI;CTD_human;UNIPROT
Hgene	CDKN2A	C0040715	Chromosomal translocation	2	CTD_human
Hgene	CDKN2A	C0041696	Unipolar Depression	2	PSYGENET
Hgene	CDKN2A	C0085390	Li-Fraumeni Syndrome	2	ORPHANET
Hgene	CDKN2A	C0086692	Benign Neoplasm	2	CTD_human
Hgene	CDKN2A	C0153633	Malignant neoplasm of brain	2	CTD_human
Hgene	CDKN2A	C0259783	mixed gliomas	2	CTD_human
Hgene	CDKN2A	C0346647	Malignant neoplasm of pancreas	2	CGI;CTD_human
Hgene	CDKN2A	C0496899	Benign neoplasm of brain, unspecified	2	CTD_human
Hgene	CDKN2A	C0555198	Malignant Glioma	2	CTD_human
Hgene	CDKN2A	C0750974	Brain Tumor, Primary	2	CTD_human
Hgene	CDKN2A	C0750977	Recurrent Brain Neoplasm	2	CTD_human
Hgene	CDKN2A	C0750979	Primary malignant neoplasm of brain	2	CTD_human
Hgene	CDKN2A	C1269683	Major Depressive Disorder	2	PSYGENET
Hgene	CDKN2A	C1527390	Neoplasms, Intracranial	2	CTD_human
Hgene	CDKN2A	C2239176	Liver carcinoma	2	CTD_human
Hgene	CDKN2A	C0001418	Adenocarcinoma	1	CTD_human
Hgene	CDKN2A	C0001624	Adrenal Gland Neoplasms	1	CTD_human
Hgene	CDKN2A	C0005940	Bone Diseases	1	CTD_human
Hgene	CDKN2A	C0006142	Malignant neoplasm of breast	1	CTD_human
Hgene	CDKN2A	C0006413	Burkitt Lymphoma	1	ORPHANET
Hgene	CDKN2A	C0007137	Squamous cell carcinoma	1	CTD_human;UNIPROT
Hgene	CDKN2A	C0008628	Chromosome Deletion	1	CTD_human
Hgene	CDKN2A	C0014859	Esophageal Neoplasms	1	CTD_human;UNIPROT
Hgene	CDKN2A	C0016325	Fluoride Poisoning	1	CTD_human
Hgene	CDKN2A	C0017601	Glaucoma	1	CTD_human
Hgene	CDKN2A	C0022783	Vulvar Lichen Sclerosus	1	CTD_human
Hgene	CDKN2A	C0023449	Acute lymphocytic leukemia	1	GENOMICS_ENGLAND
Hgene	CDKN2A	C0023453	L2 Acute Lymphoblastic Leukemia	1	CTD_human
Hgene	CDKN2A	C0024232	Lymphatic Metastasis	1	CTD_human
Hgene	CDKN2A	C0024299	Lymphoma	1	CTD_human
Hgene	CDKN2A	C0024623	Malignant neoplasm of stomach	1	CTD_human
Hgene	CDKN2A	C0025500	Mesothelioma	1	CTD_human
Hgene	CDKN2A	C0026640	Mouth Neoplasms	1	CTD_human
Hgene	CDKN2A	C0026764	Multiple Myeloma	1	CTD_human
Hgene	CDKN2A	C0027626	Neoplasm Invasiveness	1	CTD_human
Hgene	CDKN2A	C0027819	Neuroblastoma	1	CTD_human
Hgene	CDKN2A	C0032927	Precancerous Conditions	1	CTD_human
Hgene	CDKN2A	C0036920	Sezary Syndrome	1	CTD_human
Hgene	CDKN2A	C0038356	Stomach Neoplasms	1	CTD_human
Hgene	CDKN2A	C0040100	Thymoma	1	CTD_human
Hgene	CDKN2A	C0041107	Trisomy	1	CTD_human
Hgene	CDKN2A	C0042065	Genitourinary Neoplasms	1	CTD_human
Hgene	CDKN2A	C0079744	Diffuse Large B-Cell Lymphoma	1	CTD_human
Hgene	CDKN2A	C0079773	Lymphoma, T-Cell, Cutaneous	1	CTD_human
Hgene	CDKN2A	C0151779	Cutaneous Melanoma	1	CGI;CTD_human
Hgene	CDKN2A	C0153381	Malignant neoplasm of mouth	1	CTD_human
Hgene	CDKN2A	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Hgene	CDKN2A	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Hgene	CDKN2A	C0205643	Carcinoma, Cribriform	1	CTD_human
Hgene	CDKN2A	C0205644	Carcinoma, Granular Cell	1	CTD_human
Hgene	CDKN2A	C0205645	Adenocarcinoma, Tubular	1	CTD_human
Hgene	CDKN2A	C0205969	Thymic Carcinoma	1	CTD_human
Hgene	CDKN2A	C0206686	Adrenocortical carcinoma	1	CTD_human
Hgene	CDKN2A	C0206727	Nerve Sheath Tumors	1	CTD_human
Hgene	CDKN2A	C0279626	Squamous cell carcinoma of esophagus	1	CTD_human
Hgene	CDKN2A	C0279628	Adenocarcinoma Of Esophagus	1	CTD_human
Hgene	CDKN2A	C0282313	Condition, Preneoplastic	1	CTD_human
Hgene	CDKN2A	C0376407	Granulomatous Slack Skin	1	CTD_human
Hgene	CDKN2A	C0546837	Malignant neoplasm of esophagus	1	CTD_human
Hgene	CDKN2A	C0596263	Carcinogenesis	1	CTD_human
Hgene	CDKN2A	C0677866	Brain Stem Neoplasms	1	CTD_human
Hgene	CDKN2A	C0678222	Breast Carcinoma	1	CTD_human
Hgene	CDKN2A	C0750887	Adrenal Cancer	1	CTD_human
Hgene	CDKN2A	C0751569	Genitourinary Cancer	1	CTD_human
Hgene	CDKN2A	C0751606	Adult Acute Lymphocytic Leukemia	1	GENOMICS_ENGLAND
Hgene	CDKN2A	C0751689	Peripheral Nerve Sheath Neoplasm	1	CTD_human
Hgene	CDKN2A	C0751691	Perineurioma	1	CTD_human
Hgene	CDKN2A	C0751886	Brain Stem Neoplasms, Primary	1	CTD_human
Hgene	CDKN2A	C0751887	Medullary Neoplasms	1	CTD_human
Hgene	CDKN2A	C0751888	Mesencephalic Neoplasms	1	CTD_human
Hgene	CDKN2A	C0751889	Pontine Tumors	1	CTD_human
Hgene	CDKN2A	C0887833	Carcinoma, Pancreatic Ductal	1	CTD_human
Hgene	CDKN2A	C1257931	Mammary Neoplasms, Human	1	CTD_human
Hgene	CDKN2A	C1292769	Precursor B-cell lymphoblastic leukemia	1	ORPHANET
Hgene	CDKN2A	C1297882	Partial Trisomy	1	CTD_human
Hgene	CDKN2A	C1449861	Micronuclei, Chromosome-Defective	1	CTD_human
Hgene	CDKN2A	C1449862	Micronuclei, Genotoxicant-Induced	1	CTD_human
Hgene	CDKN2A	C1458155	Mammary Neoplasms	1	CTD_human
Hgene	CDKN2A	C1708349	Hereditary Diffuse Gastric Cancer	1	CTD_human
Hgene	CDKN2A	C1835042	Melanoma astrocytoma syndrome	1	CTD_human;ORPHANET
Hgene	CDKN2A	C1961099	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1	ORPHANET
Hgene	CDKN2A	C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	1	CTD_human
Hgene	CDKN2A	C2314896	Familial Atypical Mole Melanoma Syndrome	1	ORPHANET
Hgene	CDKN2A	C2930745	Partial Monosomy	1	CTD_human
Hgene	CDKN2A	C2931038	Pancreatic carcinoma, familial	1	ORPHANET
Hgene	CDKN2A	C2931822	Nasopharyngeal carcinoma	1	CTD_human
Hgene	CDKN2A	C4283859	Cutaneous Malignant Melanoma 2	1	GENOMICS_ENGLAND
Hgene	CDKN2A	C4704874	Mammary Carcinoma, Human	1	CTD_human
Hgene	CDKN2A	C4721453	Peripheral Nervous System Diseases	1	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:CDKN2A-SRGAP2 (FusionGDB2 ID:HG1029TG23380)

Fusion Gene Summary for CDKN2A-SRGAP2

Fusion Gene ORF analysis for CDKN2A-SRGAP2

Fusion Genomic Features for CDKN2A-SRGAP2

Fusion Protein Features for CDKN2A-SRGAP2

Fusion Gene Sequence for CDKN2A-SRGAP2

Fusion Gene PPI Analysis for CDKN2A-SRGAP2

Related Drugs for CDKN2A-SRGAP2

Related Diseases for CDKN2A-SRGAP2

Fusion Gene Studies
in Kim Lab