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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:CDKN2A-MTAP (FusionGDB2 ID:HG1029TG4507)

Fusion Gene Summary for CDKN2A-MTAP

check button Fusion gene summary
Fusion gene informationFusion gene name: CDKN2A-MTAP
Fusion gene ID: hg1029tg4507
HgeneTgene
Gene symbol

CDKN2A

MTAP

Gene ID

1029

4507

Gene namecyclin dependent kinase inhibitor 2Amethylthioadenosine phosphorylase
SynonymsARF|CDK4I|CDKN2|CMM2|INK4|INK4A|MLM|MTS-1|MTS1|P14|P14ARF|P16|P16-INK4A|P16INK4|P16INK4A|P19|P19ARF|TP16BDMF|DMSFH|DMSMFH|HEL-249|LGMBF|MSAP|c86fus
Cytomap('CDKN2A')('MTAP')

9p21.3

9p21.3

Type of geneprotein-codingprotein-coding
Descriptioncyclin-dependent kinase inhibitor 2ACDK4 inhibitor p16-INK4alternative reading framecell cycle negative regulator betacyclin-dependent kinase 4 inhibitor Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)multiple tumor suppressor 1S-methyl-5'-thioadenosine phosphorylase5'-methylthioadenosine phosphorylaseMTA phosphorylaseMTAPaseMeSAdo phosphorylaseepididymis luminal protein 249epididymis secretory sperm binding protein
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304494, ENST00000446177, 
ENST00000498124, ENST00000579122, 
ENST00000470819, ENST00000494262, 
ENST00000498628, ENST00000361570, 
ENST00000479692, ENST00000497750, 
ENST00000530628, ENST00000578845, 
ENST00000579755, 		ENST00000304494, 
ENST00000361570, ENST00000579122, 
ENST00000579755, ENST00000494262, 
ENST00000498124, ENST00000498628, 
ENST00000530628, ENST00000578845, 
ENST00000446177, ENST00000479692, 
ENST00000497750, ENST00000470819, 
Fusion gene scores* DoF score14 X 9 X 11=13865 X 5 X 4=100
# samples 176
** MAII scorelog2(17/1386*10)=-3.02732060599951
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CDKN2A [Title/Abstract] AND MTAP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCDKN2A(21974677)-MTAP(21815432), # samples:3
Anticipated loss of major functional domain due to fusion event.CDKN2A-MTAP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-MTAP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-MTAP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CDKN2A-MTAP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MTAP-CDKN2A seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
MTAP-CDKN2A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MTAP-CDKN2A seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
MTAP-CDKN2A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
MTAP-CDKN2A seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCDKN2A

GO:0000082

G1/S transition of mitotic cell cycle

10208428

HgeneCDKN2A

GO:0007050

cell cycle arrest

15149599

HgeneCDKN2A

GO:0008285

negative regulation of cell proliferation

15149599

HgeneCDKN2A

GO:0030308

negative regulation of cell growth

10208428

HgeneCDKN2A

GO:0032088

negative regulation of NF-kappaB transcription factor activity

10353611

HgeneCDKN2A

GO:0042326

negative regulation of phosphorylation

8259215|10208428

HgeneCDKN2A

GO:0045736

negative regulation of cyclin-dependent protein serine/threonine kinase activity

7739547|8259215

TgeneMTAP

GO:0006738

nicotinamide riboside catabolic process

19001417


check buttonFusion gene breakpoints across CDKN2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MTAP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CQ-7063-01ACDKN2Achr9

21974677

-MTAPchr9

21815432

+
ChimerDB4HNSCTCGA-CQ-7063CDKN2Achr9

21974676

-MTAPchr9

21815431

+
ChimerDB4HNSCTCGA-CQ-7063CDKN2Achr9

21974677

-MTAPchr9

21815432

+
ChimerDB4HNSCTCGA-CQ-7063CDKN2Achr9

21994820

-MTAPchr9

21815432

+


Top

Fusion Gene ORF analysis for CDKN2A-MTAP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000304494ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
5CDS-3UTRENST00000304494ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
5CDS-3UTRENST00000446177ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
5CDS-3UTRENST00000446177ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
5CDS-3UTRENST00000498124ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
5CDS-3UTRENST00000498124ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
5CDS-3UTRENST00000579122ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
5CDS-3UTRENST00000579122ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
5UTR-3CDSENST00000470819ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000470819ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000470819ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000494262ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000494262ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000494262ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000498628ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000498628ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3CDSENST00000498628ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3UTRENST00000470819ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3UTRENST00000494262ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
5UTR-3UTRENST00000498628ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
In-frameENST00000304494ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000304494ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000304494ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000304494ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000304494ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000304494ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000446177ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000446177ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000446177ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000446177ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000446177ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000446177ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000498124ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000498124ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000498124ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000498124ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000498124ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000498124ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000579122ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000579122ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000579122ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000579122ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
In-frameENST00000579122ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
In-frameENST00000579122ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000304494ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000304494ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000304494ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000361570ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000361570ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000361570ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000361570ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000446177ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000446177ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000446177ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000470819ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000470819ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000470819ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000470819ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000470819ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000470819ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000479692ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000479692ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000479692ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000479692ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000479692ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000479692ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000479692ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000479692ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000479692ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000494262ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000494262ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000494262ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000494262ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000494262ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000494262ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000497750ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000497750ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000497750ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000497750ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000497750ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000497750ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000497750ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000497750ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000497750ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000498124ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000498124ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000498124ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000498628ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000498628ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000498628ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000498628ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000498628ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000498628ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000530628ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000530628ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000530628ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000530628ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000530628ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000530628ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000530628ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000530628ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000530628ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000578845ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000578845ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000578845ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000578845ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579122ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579122ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579122ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000380172CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000380172CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000579755ENST00000380172CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000460874CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000460874CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000579755ENST00000460874CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000580900CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3CDSENST00000579755ENST00000580900CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3CDSENST00000579755ENST00000580900CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000304494ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000361570ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000361570ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000361570ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000446177ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000470819ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000470819ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000479692ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000479692ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000479692ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000494262ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000494262ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000497750ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000497750ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000497750ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000498124ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000498628ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000498628ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000530628ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000530628ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000530628ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000578845ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000578845ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000578845ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000579122ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+
intron-3UTRENST00000579755ENST00000427788CDKN2Achr9

21974677

-MTAPchr9

21815432

+
intron-3UTRENST00000579755ENST00000427788CDKN2Achr9

21974676

-MTAPchr9

21815431

+
intron-3UTRENST00000579755ENST00000427788CDKN2Achr9

21994820

-MTAPchr9

21815432

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000304494CDKN2Achr921974677-ENST00000580900MTAPchr921815432+18414211241392422
ENST00000304494CDKN2Achr921974677-ENST00000380172MTAPchr921815432+63044211241239371
ENST00000304494CDKN2Achr921974677-ENST00000460874MTAPchr921815432+15464211241239371
ENST00000579122CDKN2Achr921974677-ENST00000580900MTAPchr921815432+1601181311152373
ENST00000579122CDKN2Achr921974677-ENST00000380172MTAPchr921815432+606418131999322
ENST00000579122CDKN2Achr921974677-ENST00000460874MTAPchr921815432+130618131999322
ENST00000498124CDKN2Achr921974677-ENST00000580900MTAPchr921815432+1609189391160373
ENST00000498124CDKN2Achr921974677-ENST00000380172MTAPchr921815432+6072189391007322
ENST00000498124CDKN2Achr921974677-ENST00000460874MTAPchr921815432+1314189391007322
ENST00000446177CDKN2Achr921974677-ENST00000580900MTAPchr921815432+1782362651333422
ENST00000446177CDKN2Achr921974677-ENST00000380172MTAPchr921815432+6245362651180371
ENST00000446177CDKN2Achr921974677-ENST00000460874MTAPchr921815432+1487362651180371
ENST00000304494CDKN2Achr921974676-ENST00000580900MTAPchr921815431+18414211241392422
ENST00000304494CDKN2Achr921974676-ENST00000380172MTAPchr921815431+63044211241239371
ENST00000304494CDKN2Achr921974676-ENST00000460874MTAPchr921815431+15464211241239371
ENST00000579122CDKN2Achr921974676-ENST00000580900MTAPchr921815431+1601181311152373
ENST00000579122CDKN2Achr921974676-ENST00000380172MTAPchr921815431+606418131999322
ENST00000579122CDKN2Achr921974676-ENST00000460874MTAPchr921815431+130618131999322
ENST00000498124CDKN2Achr921974676-ENST00000580900MTAPchr921815431+1609189391160373
ENST00000498124CDKN2Achr921974676-ENST00000380172MTAPchr921815431+6072189391007322
ENST00000498124CDKN2Achr921974676-ENST00000460874MTAPchr921815431+1314189391007322
ENST00000446177CDKN2Achr921974676-ENST00000580900MTAPchr921815431+1782362651333422
ENST00000446177CDKN2Achr921974676-ENST00000380172MTAPchr921815431+6245362651180371
ENST00000446177CDKN2Achr921974676-ENST00000460874MTAPchr921815431+1487362651180371

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000304494ENST00000580900CDKN2Achr921974677-MTAPchr921815432+0.0029823340.99701774
ENST00000304494ENST00000380172CDKN2Achr921974677-MTAPchr921815432+0.0001771090.9998229
ENST00000304494ENST00000460874CDKN2Achr921974677-MTAPchr921815432+0.0008766530.9991234
ENST00000579122ENST00000580900CDKN2Achr921974677-MTAPchr921815432+0.0025095230.9974905
ENST00000579122ENST00000380172CDKN2Achr921974677-MTAPchr921815432+0.0001653710.99983466
ENST00000579122ENST00000460874CDKN2Achr921974677-MTAPchr921815432+0.0007102120.99928975
ENST00000498124ENST00000580900CDKN2Achr921974677-MTAPchr921815432+0.0024647650.9975352
ENST00000498124ENST00000380172CDKN2Achr921974677-MTAPchr921815432+0.0001652450.9998348
ENST00000498124ENST00000460874CDKN2Achr921974677-MTAPchr921815432+0.0007031080.9992969
ENST00000446177ENST00000580900CDKN2Achr921974677-MTAPchr921815432+0.003030630.9969694
ENST00000446177ENST00000380172CDKN2Achr921974677-MTAPchr921815432+0.0001764550.99982363
ENST00000446177ENST00000460874CDKN2Achr921974677-MTAPchr921815432+0.0008318240.99916816
ENST00000304494ENST00000580900CDKN2Achr921974676-MTAPchr921815431+0.0029823340.99701774
ENST00000304494ENST00000380172CDKN2Achr921974676-MTAPchr921815431+0.0001771090.9998229
ENST00000304494ENST00000460874CDKN2Achr921974676-MTAPchr921815431+0.0008766530.9991234
ENST00000579122ENST00000580900CDKN2Achr921974676-MTAPchr921815431+0.0025095230.9974905
ENST00000579122ENST00000380172CDKN2Achr921974676-MTAPchr921815431+0.0001653710.99983466
ENST00000579122ENST00000460874CDKN2Achr921974676-MTAPchr921815431+0.0007102120.99928975
ENST00000498124ENST00000580900CDKN2Achr921974676-MTAPchr921815431+0.0024647650.9975352
ENST00000498124ENST00000380172CDKN2Achr921974676-MTAPchr921815431+0.0001652450.9998348
ENST00000498124ENST00000460874CDKN2Achr921974676-MTAPchr921815431+0.0007031080.9992969
ENST00000446177ENST00000580900CDKN2Achr921974676-MTAPchr921815431+0.003030630.9969694
ENST00000446177ENST00000380172CDKN2Achr921974676-MTAPchr921815431+0.0001764550.99982363
ENST00000446177ENST00000460874CDKN2Achr921974676-MTAPchr921815431+0.0008318240.99916816

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Fusion Genomic Features for CDKN2A-MTAP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CDKN2Achr921994819-MTAPchr921815431+0.106195740.8938043
CDKN2Achr921974676-MTAPchr921815431+5.46E-070.9999994
CDKN2Achr921974676-MTAPchr921815431+5.46E-070.9999994
CDKN2Achr921994819-MTAPchr921815431+0.106195740.8938043
CDKN2Achr921974676-MTAPchr921815431+5.46E-070.9999994
CDKN2Achr921974676-MTAPchr921815431+5.46E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CDKN2A-MTAP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:21974677/chr9:21815432)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000304494-1311_4050157.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000446177-1311_4050168.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498124-1411_4050130.66666666666666RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000304494-1311_4050157.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000446177-1311_4050168.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498124-1411_4050130.66666666666666RepeatNote=ANK 1
TgeneMTAPchr9:21974676chr9:21815431ENST0000038017208220_22211284.0RegionNote=Substrate binding
TgeneMTAPchr9:21974676chr9:21815431ENST000003801720860_6111284.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974676chr9:21815431ENST000003801720893_9411284.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974676chr9:21815431ENST0000058090008220_22211335.0RegionNote=Substrate binding
TgeneMTAPchr9:21974676chr9:21815431ENST000005809000860_6111335.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974676chr9:21815431ENST000005809000893_9411335.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974677chr9:21815432ENST0000038017208220_22211284.0RegionNote=Substrate binding
TgeneMTAPchr9:21974677chr9:21815432ENST000003801720860_6111284.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974677chr9:21815432ENST000003801720893_9411284.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974677chr9:21815432ENST0000058090008220_22211335.0RegionNote=Substrate binding
TgeneMTAPchr9:21974677chr9:21815432ENST000005809000860_6111335.0RegionNote=Phosphate binding
TgeneMTAPchr9:21974677chr9:21815432ENST000005809000893_9411335.0RegionNote=Phosphate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000304494-13110_13950157.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000304494-1344_7250157.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000304494-1377_10650157.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000446177-13110_13950168.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000446177-1344_7250168.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000446177-1377_10650168.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000494262-14110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000494262-1411_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000494262-1444_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000494262-1477_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498124-14110_13950130.66666666666666RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498124-1444_7250130.66666666666666RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498124-1477_10650130.66666666666666RepeatNote=ANK 3
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498628-13110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498628-1311_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498628-1344_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000498628-1377_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000578845-12110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000578845-1211_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000578845-1244_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000578845-1277_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000304494-13110_13950157.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000304494-1344_7250157.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000304494-1377_10650157.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000446177-13110_13950168.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000446177-1344_7250168.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000446177-1377_10650168.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000494262-14110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000494262-1411_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000494262-1444_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000494262-1477_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498124-14110_13950130.66666666666666RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498124-1444_7250130.66666666666666RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498124-1477_10650130.66666666666666RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498628-13110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498628-1311_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498628-1344_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000498628-1377_1060106.0RepeatNote=ANK 3
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000578845-12110_1390106.0RepeatNote=ANK 4
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000578845-1211_400106.0RepeatNote=ANK 1
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000578845-1244_720106.0RepeatNote=ANK 2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000578845-1277_1060106.0RepeatNote=ANK 3


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Fusion Gene Sequence for CDKN2A-MTAP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>15410_15410_1_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000380172_length(transcript)=6304nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGA
GAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTG
CCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAA
AGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTG
CAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGC
GACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACT
CTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATATAAAGAAGGGTGTTTAATAATGATAGTTATAA
TAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAA
TCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGT
TTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGAT
AATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTG
GATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGG
AGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAG
CTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTT
GATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTT
TTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGG
ATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGG
TGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCA
GTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGT
TTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGA
TACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTA
AACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGT
AGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGT
GATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGG
GCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCAT
TTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCTTATGCAAAGCCAATATAATTTTCCTCATAC
CTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAG
TATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTG
ACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAATCTGCTGTTATATTTGGCATGGATTTTCAT
GGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACG
AGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGT
GAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCAT
CCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCCACCAACACCTATTTTCCAAATAATTATTCA
TTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCA
AGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCC
ACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTT
ACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTT
CCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGA
GTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCATGAGAATGGACTAATACACTCCTCAAATGT
TTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTC
CAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGA
AAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCC
TTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACT
CATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATGCCTATCTTACAATTTGATTATCTATTCACC
TGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATA
TTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCC
ATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCC
ATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGT
TTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCT
TTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGC
CTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTAATTACCTTGCCTACTCATTTAATTACCTGT
GTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCC
ACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTC
CTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGA
AGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTT
GTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAAT
TTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTTTATATTCTGTAATCTTATTAAATTCACTTAG

>15410_15410_1_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000380172_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_2_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000460874_length(transcript)=1546nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGA
GAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTG
CCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAA
AGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTG

>15410_15410_2_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000460874_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_3_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000580900_length(transcript)=1841nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTC
ACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATA
CTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCACAGAACAATCACCATCACACCTCTGTCAGC
AGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAAT
TAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTC
TCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTT
CCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAATCGTGGAGTTTAACTGGTATACAGACTTCCT

>15410_15410_3_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000304494_MTAP_chr9_21815431_ENST00000580900_length(amino acids)=422AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKM

--------------------------------------------------------------
>15410_15410_4_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000380172_length(transcript)=6245nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTAC
CAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAAT
ATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAA
TGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAAC
CCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAA
GAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTT
AAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATAT
AAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTT
ATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAA
AAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTT
GTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATC
AAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGT
TGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGT
ACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTT
ATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAAT
AAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAA
TCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACT
AAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGG
GAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCA
AAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTG
TAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGA
TTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAA
GTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTG
AACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATA
GGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTC
TTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCC
TTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCT
GTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATG
GTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATA
ATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTG
GCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGG
TACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCC
CTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCC
CACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCAC
TTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAG
TCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCC
AGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAG
GGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTC
CTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGC
ATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATAT
ATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAG
AAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGA
AGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGC
ATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATAT
GCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAA
GCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAG
CTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGA
TGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTG
TTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTT
AGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTG
GTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTT
AATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTT
ATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCA
ATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGG
AATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTG
GGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTT
GTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTT

>15410_15410_4_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000380172_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_5_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000460874_length(transcript)=1487nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTAC
CAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAAT
ATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAA
TGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAAC

>15410_15410_5_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000460874_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_6_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000580900_length(transcript)=1782nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTG
AGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCC
TGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCC
ACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGAT
TTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCAT
CAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATA
GAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAA

>15410_15410_6_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000446177_MTAP_chr9_21815431_ENST00000580900_length(amino acids)=422AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKM

--------------------------------------------------------------
>15410_15410_7_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000380172_length(transcript)=6072nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTT
TTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGA
AAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGAC
TCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAA
AAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATG
TGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAA
AAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAAT
TATATATAAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGT
CTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGA
AGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATA
TAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAA
TTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAA
TTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCA
GAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGC
ACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCT
TTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATC
CATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGT
CTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTG
AACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC
AGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTT
TTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTC
TCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTT
GGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAAT
GAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATT
CTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGT
ACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCAT
TCACTCCTTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTG
TGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGG
ATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGG
CCTTATAATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTG
TGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAA
ACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCC
AGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTT
GTGGCCCCACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAG
CCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATT
TGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGA
GGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTT
TTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGT
AAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTA
CAGCAGCATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAA
TGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGAT
AGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTC
CAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAA
TCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCT
GTCATATGCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCT
GCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTT
GACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGA
TTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAAT
TAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTT
AGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTT
ATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTA
CTCACTTAATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTAT
GTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAG
CTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAAT
CTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCAT
TTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAA
ATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATA

>15410_15410_7_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000380172_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_8_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000460874_length(transcript)=1314nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTT
TTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGA
AAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGAC
TCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAA

>15410_15410_8_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000460874_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_9_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000580900_length(transcript)=1609nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATC
CTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGT
GAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCC
AAGACCCACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGT
CATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGG
TGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCA
ATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGA

>15410_15410_9_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000498124_MTAP_chr9_21815431_ENST00000580900_length(amino acids)=373AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV
SVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKMIKFQMILSEGYHPFNIQESPFYRGLLDFPSVGHGRGEILPLSPLDLAGY

--------------------------------------------------------------
>15410_15410_10_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000380172_length(transcript)=6064nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACC
AAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATA
TGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAAT
GATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACC
CACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAG
AAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTA
AAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATATA
AAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTA
TAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAA
AAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTG
TTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCA
AATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTT
GGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTA
CTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTA
TGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATA
AAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAAT
CCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTA
AAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGG
AGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAA
AAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGT
AGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGAT
TGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAG
TATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGA
ACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAG
GTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCT
TGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCT
TATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTG
TACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGG
TGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAA
TCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGG
CCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGT
ACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCC
TGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCC
ACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACT
TATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGT
CCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCA
GTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGG
GGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCC
TGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCA
TGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATA
TTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGA
AGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAA
GCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCA
TGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATG
CCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAG
CATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGC
TTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGAT
GTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGT
TTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTA
GCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGG
TGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTA
ATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTA
TCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAA
TCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGA
ATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGG
GCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTG
TGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTTT

>15410_15410_10_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000380172_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_11_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000460874_length(transcript)=1306nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACC
AAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATA
TGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAAT
GATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACC

>15410_15410_11_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000460874_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_12_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000580900_length(transcript)=1601nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGA
GGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCT
GCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCA
CAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATT
TTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATC
AGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAG
AAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAAT

>15410_15410_12_CDKN2A-MTAP_CDKN2A_chr9_21974676_ENST00000579122_MTAP_chr9_21815431_ENST00000580900_length(amino acids)=373AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV
SVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKMIKFQMILSEGYHPFNIQESPFYRGLLDFPSVGHGRGEILPLSPLDLAGY

--------------------------------------------------------------
>15410_15410_13_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6304nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGA
GAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTG
CCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAA
AGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTG
CAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGC
GACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACT
CTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATATAAAGAAGGGTGTTTAATAATGATAGTTATAA
TAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAA
TCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGT
TTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGAT
AATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTG
GATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGG
AGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAG
CTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTT
GATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTT
TTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGG
ATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGG
TGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCA
GTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGT
TTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGA
TACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTA
AACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGT
AGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGT
GATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGG
GCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCAT
TTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCTTATGCAAAGCCAATATAATTTTCCTCATAC
CTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAG
TATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTG
ACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAATCTGCTGTTATATTTGGCATGGATTTTCAT
GGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACG
AGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGT
GAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCAT
CCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCCACCAACACCTATTTTCCAAATAATTATTCA
TTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCA
AGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCC
ACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTT
ACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTT
CCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGA
GTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCATGAGAATGGACTAATACACTCCTCAAATGT
TTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTC
CAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGA
AAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCC
TTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACT
CATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATGCCTATCTTACAATTTGATTATCTATTCACC
TGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATA
TTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCC
ATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCC
ATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGT
TTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCT
TTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGC
CTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTAATTACCTTGCCTACTCATTTAATTACCTGT
GTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCC
ACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTC
CTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGA
AGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTT
GTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAAT
TTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTTTATATTCTGTAATCTTATTAAATTCACTTAG

>15410_15410_13_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_14_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1546nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGA
GAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTG
CCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAA
AGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTG

>15410_15410_14_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_15_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1841nt_BP=421nt
CCCAACCTGGGGCGACTTCAGGGGTGCCACATTCGCTAAGTGCTCGGAGTTAATAGCACCTCCTCCGAGCACTCGCTCACGGCGTCCCCT
TGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCTCTTCCGCCAGCACCGGAGGAAGAAAGAGGAG
GGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAG
CATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGC
GCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGA
TGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAA
AAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTT
GAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGA
TCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGC
TGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCAC
AATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGA
GGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGT
TTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCCAC
AGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTC
ACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATA
CTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCACAGAACAATCACCATCACACCTCTGTCAGC
AGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAAT
TAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTC
TCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTT
CCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAATCGTGGAGTTTAACTGGTATACAGACTTCCT

>15410_15410_15_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000304494_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=422AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKM

--------------------------------------------------------------
>15410_15410_16_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6245nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTAC
CAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAAT
ATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAA
TGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAAC
CCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAA
GAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTT
AAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATAT
AAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTT
ATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAA
AAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTT
GTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATC
AAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGT
TGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGT
ACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTT
ATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAAT
AAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAA
TCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACT
AAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGG
GAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCA
AAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTG
TAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGA
TTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAA
GTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTG
AACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATA
GGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTC
TTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCC
TTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCT
GTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATG
GTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATA
ATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTG
GCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGG
TACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCC
CTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCC
CACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCAC
TTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAG
TCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCC
AGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAG
GGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTC
CTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGC
ATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATAT
ATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAG
AAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGA
AGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGC
ATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATAT
GCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAA
GCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAG
CTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGA
TGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTG
TTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTT
AGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTG
GTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTT
AATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTT
ATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCA
ATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGG
AATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTG
GGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTT
GTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTT

>15410_15410_16_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_17_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1487nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTAC
CAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAAT
ATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAA
TGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAAC

>15410_15410_17_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=371AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKN

--------------------------------------------------------------
>15410_15410_18_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1782nt_BP=362nt
CTCCTCCGAGCACTCGCTCACGGCGTCCCCTTGCCTGGAAAGATACCGCGGTCCCTCCAGAGGATTTGAGGGACAGGGTCGGAGGGGGCT
CTTCCGCCAGCACCGGAGGAAGAAAGAGGAGGGGCTGGCTGGTCACCAGAGGGTGGGGCGGACCGCGTGCGCTCGGCGGCTGCGGAGAGG
GGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCG
CGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCC
AGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC
CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAA
AGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG
AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTT
GTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC
TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGG
CGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATT
ATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTAC
TGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTG
AGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCC
TGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCC
ACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGAT
TTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCAT
CAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATA
GAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAA

>15410_15410_18_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000446177_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=422AA_BP=99
MRDRVGGGSSASTGGRKRRGWLVTRGWGGPRALGGCGEGESRQRAAGSSMEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAP
NSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVT
TACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAE
SFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKM

--------------------------------------------------------------
>15410_15410_19_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6072nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTT
TTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGA
AAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGAC
TCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAA
AAAAAACCCACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATG
TGAGGAAGAAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAA
AAGACTTAAAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAAT
TATATATAAAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGT
CTTAGTTATAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGA
AGTGAAAAAAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATA
TAACCTTGTTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAA
TTTAATCAAATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAA
TTTAAGTTGGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCA
GAACAGTACTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGC
ACATTTTATGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCT
TTTTAATAAAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATC
CATGTAATCCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGT
CTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTG
AACCTGGGAGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTC
AGTCTCAAAAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTT
TTCACTGTAGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTC
TCTGAGATTGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTT
GGGTCAAGTATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAAT
GAACCTGAACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATT
CTTAATAGGTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGT
ACTTTTCTTGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCAT
TCACTCCTTATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTG
TGATGCTGTACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGG
ATGGATGGTGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGG
CCTTATAATCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTG
TGACCTGGCCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAA
ACTCTGGTACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCC
AGCTGCCCTGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTT
GTGGCCCCACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAG
CCAGCACTTATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATT
TGCAGAGTCCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGA
GGGACCCAGTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTT
TTATAAGGGGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGT
AAGTTTCCTGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTA
CAGCAGCATGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAA
TGTATATATTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGAT
AGGCAAGAAGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTC
CAGAAGAAGCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAA
TCTCGGCATGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCT
GTCATATGCCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCT
GCTATAAGCATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTT
GACAAAGCTTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGA
TTAAAGATGTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAAT
TAGATTGTTTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTT
AGTCTTTAGCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTT
ATGGTTGGTGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTA
CTCACTTAATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTAT
GTCATTTATCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAG
CTTTGCAATCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAAT
CTGCTGGAATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCAT
TTATTTGGGCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAA
ATATTTTGTGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATA

>15410_15410_19_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_20_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1314nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTT
TTATTACCAAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGA
AAAAAATATGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGAC
TCCTGAATGATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAA

>15410_15410_20_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_21_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1609nt_BP=189nt
GGAGAGGGGGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCC
ACGGCCGCGGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGG
CCGATCCAGATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTT
GGCAAGCCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATG
CCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTG
AGGGAGGAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGT
CATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAG
CTAGGACTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACC
TGGGGGGCGGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCG
ACAGATTATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAA
AGCTTACTGCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATC
CTCAGTGAGGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGT
GAAATCCTGCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCC
AAGACCCACAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGT
CATGGATTTTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGG
TGAGCATCAGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCA
ATAGATAGAAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGA

>15410_15410_21_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000498124_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=373AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV
SVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKMIKFQMILSEGYHPFNIQESPFYRGLLDFPSVGHGRGEILPLSPLDLAGY

--------------------------------------------------------------
>15410_15410_22_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000380172_length(transcript)=6064nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACC
AAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATA
TGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAAT
GATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACC
CACCATTCTCTTCTCCCCCTATTAAATTTGCAACAATAAAGGGTGGAGGGTAATCTCTACTTTCCTATACTGCCAAAGAATGTGAGGAAG
AAATGGGACTCTTTGGTTATTTATTGATGCGACTGTAAATTGGTACAGTATTTCTGGAGGGCAATTTGGTAAAATGCATCAAAAGACTTA
AAAATACGGACGTACTTTGTGCTGGGAACTCTACATCTAGCAATTTCTCTTTAAAACCATATCAGAGATGCATACAAAGAATTATATATA
AAGAAGGGTGTTTAATAATGATAGTTATAATAATAAATAATTGAAACAATCTGAATCCCTTGCAATTGGAGGTAAATTATGTCTTAGTTA
TAATTAGATTGTGAATCAGCCAACTGAAAATCCTTTTTGCATATTTCAATGTCCTAAAAAGACACGGTTGCTCTATATATGAAGTGAAAA
AAGGATATGGTAGCATTTTATAGTACTAGTTTTGCTTTAAAATGCTATGTAAATATACAAAAAAACTAGAAAGAAATATATATAACCTTG
TTATTGTATTTGGGGGAGGGATACTGGGATAATTTTTATTTTCTTTGAATCTTTCTGTGTCTTCACATTTTTCTACAGTGAATTTAATCA
AATAGTAAAGTTGTTGTAAAAATAAAAGTGGATTTAGAAAGATCCAGTTCTTGAAAACACTGTTTCTGGTAATGAAGCAGAATTTAAGTT
GGTAATATTAAGGTGAATGTCATTTAAGGGAGTTACATCTTTATTCTGCTAAAGAAGAGGATCATTGATTTCTGTACAGTCAGAACAGTA
CTTGGGTTTGCAACAGCTTTCTGAGAAAAGCTAGGTGTTTAATAGTTTAACTGAAAGTTTAACTATTTAAAAGACTAAATGCACATTTTA
TGGTATCTGATATTTTAAAAAGTAATGTTTGATTCTCCTTTTTATGAGTTAAATTATTTTATACGAGTTGGTAATTTTTGCTTTTTAATA
AAGTGGAAGCTTGCTTTTTTAACTCTTTTTTTATTGTTATTTTATAGAAATGCTTTTTGTTGGCCGGGCACAGTTGCTCATCCATGTAAT
CCCAGCACTGTGGGAGGCCGAGACGGGTGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCTAATGCGTTGAAACTCCGTCTCTACTA
AAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGTGTGAACCTGGG
AGGTGGAGCTTGCAGTGAGCAGAGCTTGCAGTGAGACGAGCTTGTGCCACTGCACTCCAGCCTGGGCAACAGAGTAAGACTCAGTCTCAA
AAAAAAAAAAAAGAGTGAAATGCTTTTTGTTTGCTTCAGTTTTTTATCATGGGGAGATCTTTTTCCTCAGAATTGTTTTCTTTTCACTGT
AGGCTATTACAGGATACTTCAGGATCAAGATACAGAACCTTTTATTTAAAGAGTTTGTAAAGTCAATGTGTTTGTTTGTGTCTCTGAGAT
TGACTTCAAGATAATAAGCTGCTAATTGTAAACAAAACAGTTACCCTCCAGTATTAATATGACTCATTAGTGTGAGCCATTTGGGTCAAG
TATGATTATGACCCTTGGACTTCCTGATGTAGTATTAAATTTCAACTCTGGTTATCCATTAGCAATCTGTAGAGAACTTAATGAACCTGA
ACCCAGGCTTCTCTAGCTCTGGTAACGTGTGATTGTTTTCACTACAATATGATACATAGATGGTACCTTACTTTTCCTCATTCTTAATAG
GTGTCTAAGAATGTCAGGGCAAAAGTATGGGCATTTTTCTTGCTATGTTCAGAAAGTACAGTTCTCTCCAACTTGCAGAGGTACTTTTCT
TGATTAAATAGCCTTCTCTAGCAACATCATTTTCAGACTAACTAAATGAATGCAGTATACTCTTTTCTTTGTTCTCAATCATTCACTCCT
TATGCAAAGCCAATATAATTTTCCTCATACCTTATGCTTGAGGATATTGTTGAAGAACACTTCCTGGAACACTTCTCACTTGTGATGCTG
TACTAATTTTTTTTTTTTAATTTAAGCTAGTATACTAAGTGAACACCATGGTCAGTTGTGAGCATTTTGGTTTCCGCAAAGGATGGATGG
TGAGCATCATGGGAAAGCTGTAGTTTAGTGACTTAGCCCTTAGTGATTAATAGATTTGCATGTACATAGAAGTCTTTGTTGGCCTTATAA
TCTGCTGTTATATTTGGCATGGATTTTCATGGTTTTGAGAATGACATCCTGGCCCTGTGGTCCCCGAGGGTCATGGTCCTTGTGACCTGG
CCCCTGTTCACTGCCCCCTTCGCTAGCACGAGTTGCTGTGCAGGGCTGGAGGTAGCTACCATGGCTTGTTTCAAGGAAGGAAACTCTGGT
ACGGTGGCACCCTCAGGAGTGGAGGACAGTGAACTTCCTTGAAGAGGGAGTGACTAAGGTGACCTCCAACCTGCCCTGAGCCAGCTGCCC
TGCAGGTGCCACGTGAGCCTGCTCTGGCATCCACAGGATGCTCCTGGAGCCTCTTCTCTGGCTGCTACCTCAGGGCATGGTTGTGGCCCC
ACCAACACCTATTTTCCAAATAATTATTCATTCTTGTGACAGTGGCCTGAACATGTTTTTAATTTTCTCAACAAGCATTTAGCCAGCACT
TATCCAGTGAAACAATTTGATAAGGTTTCAAGGAGTATCTGATGGGTTAGGAAGTCACGAAATGAGGAGTTCTTGCCACATTTGCAGAGT
CCCTCCTTGATAAGGTTTGGCGGTGTCCCCACCCAAATCTCATGTTGAATTGTAGTTCCCATAATCCCCACATGTTGTGGGAGGGACCCA
GTGGGAGGTAATTAAATCATGGGGGTGGTTACCCCCACACTGCTGTTCTCATGATACTGAGTTCTCACAAGTCCTGTTTGTTTTATAAGG
GGCTTTTCCCCCTTTTGCTCAACACTTCTTCCTGCCATCATGTGAAGAAGGACGTGTTTGTTTCCCCTTCTGCCACGATTGTAAGTTTCC
TGAGGCCTTCCCAGCTATGTGGAACTGTGAGTTAATTAAACCTCTTTCCTTTATAAATTACCCAGTCATGGGCAGTCCTTTACAGCAGCA
TGAGAATGGACTAATACACTCCTCAAATGTTTTGAAGATTGTTGCACCTTGGAACTACCAGTGTGCACACAATCTGGCTCAATGTATATA
TTGGCCCAGCAAGGCAAAGAACTGAAGTTCCAGGATGGAAGAACCTGTGTTCTCCTCATAATAGTATAGAATAATTCAAGATAGGCAAGA
AGGACAGCAGTAAATGAAGACCATGGAAGAAAAGAAGGAATGCCAAAGATCGAGGAAATCTACCAAGACTAGTAGGGTAGTCCAGAAGAA
GCTGTTTCAGGGCCTGTTGCCAGCTATGCCTTTGAGAACCTCGGGATCCCAAAGAATGAGGGGAATTTCTTCAGAAAGACAATCTCGGCA
TGCATTATTTCTTTGTTTTGAAGATTCACTCATGTTGCATGCATCTGTAGCTTGTGCCTTTTTTATTGCCTAGTAGTATTCTGTCATATG
CCTATCTTACAATTTGATTATCTATTCACCTGTTGATGAATGTTTGAATTTTTTCCATTTGAGGAATTTTATGAATAAAGCTGCTATAAG
CATGAAATTACAAGTCTTTTTGTGAACATATTTTCACTTGTGCAAATGCCTATACTCCCACCAGTAATTTGTAAGAATTCTTGACAAAGC
TTGGTATTGTCAGCGTTTTTAATTTTAGCCATTCTATTGGGTATATTTTGATATCTCGTGGTTTTGATTTGCATTTTTCTGATTAAAGAT
GTTGAACTTCTTTTCATGTGCTTATTGGCCATTCACATATTTCGTGAACTATCTGTACAAATATTTTTGTTTATTAAAAAATTAGATTGT
TTTGTTTTATTATTGAATAGTAAGAATTGTTTATATATTCTGGATACACTCTTTTTCAGATATGTGTGTTGTGACTATTCTTAGTCTTTA
GCTTGCCTTTTCATTTTCTTAATTATGTCTTTCAAAGAACAAGTTTTTCATTTTGACGAAGCCTAGTTTATCAATTTTTTTTATGGTTGG
TGCTTTTTGTGTGTTCCAAGAAATCTTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATCATTTAATTTTGACTACTCACTTA
ATTACCTTGCCTACTCATTTAATTACCTGTGTGCCCTTGTCAAAATTTACTGTTTATCTGTGAATCTGGATGATCTATTTATGTCATTTA
TCTATGTGTCTCTTCTTATGCCAGTACCCCACTGTCTTGATTATTGTGGCTTTATGGTGTCTTGAAATTAAGTATTGTTAAGCTTTGCAA
TCTTTTCCAAGATTGTTTTGGCTATAGGTCCTTTCTTTATAAAGTTTATATTAAGCTTCTCCATTTTTCTTTAAGAAAAAATCTGCTGGA
ATGGCACTGAATTTTTAGGTCGATTTGGGAAGAATTGACAATATTGAACCTTTCAATCGATGGACATGGTATGTTTCTGCATTTATTTGG
GCCTTTTAAAATTTATCTCAGCAATATTTTGTAGTTTTAGTGAAGAAGTCTTGTATATATCTTTTGTTAAATGTATTCCTAAATATTTTG
TGGAAATGTTACTGTAAATAGTACTTTAATTTCATTTTTAAGTTTATTGCTGGTATACAGAAATATGTTTTATTTTTGTATATTGACTTT

>15410_15410_22_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000380172_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

--------------------------------------------------------------
>15410_15410_23_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000460874_length(transcript)=1306nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTACC
AAGACATTAAAGTAGCATGGCTGCCCAGGAGAAAAGAAGACATTCTAATTCCAGTCATTTTGGGAATTCCTGCTTAACTTGAAAAAAATA
TGGGAAAGACATGCAGCTTTCATGCCCTTGCCTATCAAAGAGTATGTTGTAAGAAAGACAAGACATTGTGTGTATTAGAGACTCCTGAAT
GATTTAGACAACTTCAAAATACAGAAGAAAAGCAAATGACTAGTAAACATGTGGGAAAAAATATTACATTTTAAGGGGGAAAAAAAAACC

>15410_15410_23_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000460874_length(amino acids)=322AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV

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>15410_15410_24_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000580900_length(transcript)=1601nt_BP=181nt
GGAGAGCAGGCAGCGGGCGGCGGGGAGCAGCATGGAGCCGGCGGCGGGGAGCAGCATGGAGCCTTCGGCTGACTGGCTGGCCACGGCCGC
GGCCCGGGGTCGGGTAGAGGAGGTGCGGGCGCTGCTGGAGGCGGGGGCGCTGCCCAACGCACCGAATAGTTACGGTCGGAGGCCGATCCA
GATTGGAATAATTGGTGGAACAGGCCTGGATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGCC
ATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCGTCCTCCTTGCAAGGCATGGAAGGCAGCACACCATCATGCCTTCAAA
GGTCAACTACCAGGCGAACATCTGGGCTTTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGGA
GATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGACCTCAGTCCTTCTATGATGGAAGTCATTCTTG
TGCCAGAGGAGTGTGCCATATTCCAATGGCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGACT
CCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGGCAGAAAGCTTCATGTTCCGCACCTGGGGGGC
GGATGTTATCAACATGACCACAGTTCCAGAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGATTA
TGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTGAAAGAAAACGCTAATAAAGCCAAAAGCTTACT
GCTCACTACCATACCTCAGATAGGGTCCACAGAATGGTCAGAAACCCTCCATAACCTGAAGATGATCAAGTTCCAGATGATCCTCAGTGA
GGGATACCATCCTTTCAATATTCAAGAGTCACCCTTCTACAGAGGACTCCTAGACTTCCCATCAGTGGGACATGGCAGAGGTGAAATCCT
GCCCCTGTCTCCCTTAGACCTGGCTGGATACTGCTTCCAACAACCCATGCAGCCACCCTGCCCTGACAGCTAGCAAGAGGCCAAGACCCA
CAGAACAATCACCATCACACCTCTGTCAGCAGGAAGCAGTTACAGAAGACTGACCTTCATCCAGTTTCCCAAAGAATTGGGTCATGGATT
TTTGCGGGGGAAAATGTTAGAGTAGGTAATTAGGCAGACATGAGTAAGGGAGGAGAGACCCCCTCCAACTAGGAATGTCAGGTGAGCATC
AGATGATCATCAGGTGGTTGTTAAACTCTCTCTCTAAAATAATAATAGGTTGCAACTGGCAGCAGGGAAAGACAATCTCCCAATAGATAG
AAAAGTCCTGAAGCTGGTGATCAGCAGCTTCCTAGTAAGATCTCAGGATTTGGGCAAGCAGGCTCAAACATGGGCACTAAGAGGCAAAAT

>15410_15410_24_CDKN2A-MTAP_CDKN2A_chr9_21974677_ENST00000579122_MTAP_chr9_21815432_ENST00000580900_length(amino acids)=373AA_BP=50
MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIK
NVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMA
EPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAV
SVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKMIKFQMILSEGYHPFNIQESPFYRGLLDFPSVGHGRGEILPLSPLDLAGY

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Fusion Gene PPI Analysis for CDKN2A-MTAP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000361570-131_640220.0CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000530628-131_640122.66666666666667CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974676chr9:21815431ENST00000579755-131_640134.33333333333334CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000361570-131_640220.0CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000530628-131_640122.66666666666667CDK5RAP3 and MDM2
HgeneCDKN2Achr9:21974677chr9:21815432ENST00000579755-131_640134.33333333333334CDK5RAP3 and MDM2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CDKN2A-MTAP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CDKN2A-MTAP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCDKN2AC1835044MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 213CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCDKN2AC1838547MELANOMA-PANCREATIC CANCER SYNDROME10CLINGEN;CTD_human
HgeneCDKN2AC0024121Lung Neoplasms4CTD_human;UNIPROT
HgeneCDKN2AC0242379Malignant neoplasm of lung4CTD_human
HgeneCDKN2AC0011570Mental Depression3PSYGENET
HgeneCDKN2AC0011581Depressive disorder3PSYGENET
HgeneCDKN2AC0023903Liver neoplasms3CTD_human
HgeneCDKN2AC0345904Malignant neoplasm of liver3CTD_human
HgeneCDKN2AC0345967Malignant mesothelioma3CTD_human
HgeneCDKN2AC1168401Squamous cell carcinoma of the head and neck3CTD_human
HgeneCDKN2AC0005684Malignant neoplasm of urinary bladder2CTD_human
HgeneCDKN2AC0005695Bladder Neoplasm2CTD_human;UNIPROT
HgeneCDKN2AC0006118Brain Neoplasms2CTD_human
HgeneCDKN2AC0006826Malignant Neoplasms2CGI;CTD_human
HgeneCDKN2AC0007131Non-Small Cell Lung Carcinoma2CTD_human;UNIPROT
HgeneCDKN2AC0017638Glioma2CGI;CTD_human
HgeneCDKN2AC0023452Childhood Acute Lymphoblastic Leukemia2CTD_human;GENOMICS_ENGLAND
HgeneCDKN2AC0025202melanoma2CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneCDKN2AC0027651Neoplasms2CTD_human
HgeneCDKN2AC0030297Pancreatic Neoplasm2CGI;CTD_human;UNIPROT
HgeneCDKN2AC0040715Chromosomal translocation2CTD_human
HgeneCDKN2AC0041696Unipolar Depression2PSYGENET
HgeneCDKN2AC0085390Li-Fraumeni Syndrome2ORPHANET
HgeneCDKN2AC0086692Benign Neoplasm2CTD_human
HgeneCDKN2AC0153633Malignant neoplasm of brain2CTD_human
HgeneCDKN2AC0259783mixed gliomas2CTD_human
HgeneCDKN2AC0346647Malignant neoplasm of pancreas2CGI;CTD_human
HgeneCDKN2AC0496899Benign neoplasm of brain, unspecified2CTD_human
HgeneCDKN2AC0555198Malignant Glioma2CTD_human
HgeneCDKN2AC0750974Brain Tumor, Primary2CTD_human
HgeneCDKN2AC0750977Recurrent Brain Neoplasm2CTD_human
HgeneCDKN2AC0750979Primary malignant neoplasm of brain2CTD_human
HgeneCDKN2AC1269683Major Depressive Disorder2PSYGENET
HgeneCDKN2AC1527390Neoplasms, Intracranial2CTD_human
HgeneCDKN2AC2239176Liver carcinoma2CTD_human
HgeneCDKN2AC0001418Adenocarcinoma1CTD_human
HgeneCDKN2AC0001624Adrenal Gland Neoplasms1CTD_human
HgeneCDKN2AC0005940Bone Diseases1CTD_human
HgeneCDKN2AC0006142Malignant neoplasm of breast1CTD_human
HgeneCDKN2AC0006413Burkitt Lymphoma1ORPHANET
HgeneCDKN2AC0007137Squamous cell carcinoma1CTD_human;UNIPROT
HgeneCDKN2AC0008628Chromosome Deletion1CTD_human
HgeneCDKN2AC0014859Esophageal Neoplasms1CTD_human;UNIPROT
HgeneCDKN2AC0016325Fluoride Poisoning1CTD_human
HgeneCDKN2AC0017601Glaucoma1CTD_human
HgeneCDKN2AC0022783Vulvar Lichen Sclerosus1CTD_human
HgeneCDKN2AC0023449Acute lymphocytic leukemia1GENOMICS_ENGLAND
HgeneCDKN2AC0023453L2 Acute Lymphoblastic Leukemia1CTD_human
HgeneCDKN2AC0024232Lymphatic Metastasis1CTD_human
HgeneCDKN2AC0024299Lymphoma1CTD_human
HgeneCDKN2AC0024623Malignant neoplasm of stomach1CTD_human
HgeneCDKN2AC0025500Mesothelioma1CTD_human
HgeneCDKN2AC0026640Mouth Neoplasms1CTD_human
HgeneCDKN2AC0026764Multiple Myeloma1CTD_human
HgeneCDKN2AC0027626Neoplasm Invasiveness1CTD_human
HgeneCDKN2AC0027819Neuroblastoma1CTD_human
HgeneCDKN2AC0032927Precancerous Conditions1CTD_human
HgeneCDKN2AC0036920Sezary Syndrome1CTD_human
HgeneCDKN2AC0038356Stomach Neoplasms1CTD_human
HgeneCDKN2AC0040100Thymoma1CTD_human
HgeneCDKN2AC0041107Trisomy1CTD_human
HgeneCDKN2AC0042065Genitourinary Neoplasms1CTD_human
HgeneCDKN2AC0079744Diffuse Large B-Cell Lymphoma1CTD_human
HgeneCDKN2AC0079773Lymphoma, T-Cell, Cutaneous1CTD_human
HgeneCDKN2AC0151779Cutaneous Melanoma1CGI;CTD_human
HgeneCDKN2AC0153381Malignant neoplasm of mouth1CTD_human
HgeneCDKN2AC0205641Adenocarcinoma, Basal Cell1CTD_human
HgeneCDKN2AC0205642Adenocarcinoma, Oxyphilic1CTD_human
HgeneCDKN2AC0205643Carcinoma, Cribriform1CTD_human
HgeneCDKN2AC0205644Carcinoma, Granular Cell1CTD_human
HgeneCDKN2AC0205645Adenocarcinoma, Tubular1CTD_human
HgeneCDKN2AC0205969Thymic Carcinoma1CTD_human
HgeneCDKN2AC0206686Adrenocortical carcinoma1CTD_human
HgeneCDKN2AC0206727Nerve Sheath Tumors1CTD_human
HgeneCDKN2AC0279626Squamous cell carcinoma of esophagus1CTD_human
HgeneCDKN2AC0279628Adenocarcinoma Of Esophagus1CTD_human
HgeneCDKN2AC0282313Condition, Preneoplastic1CTD_human
HgeneCDKN2AC0376407Granulomatous Slack Skin1CTD_human
HgeneCDKN2AC0546837Malignant neoplasm of esophagus1CTD_human
HgeneCDKN2AC0596263Carcinogenesis1CTD_human
HgeneCDKN2AC0677866Brain Stem Neoplasms1CTD_human
HgeneCDKN2AC0678222Breast Carcinoma1CTD_human
HgeneCDKN2AC0750887Adrenal Cancer1CTD_human
HgeneCDKN2AC0751569Genitourinary Cancer1CTD_human
HgeneCDKN2AC0751606Adult Acute Lymphocytic Leukemia1GENOMICS_ENGLAND
HgeneCDKN2AC0751689Peripheral Nerve Sheath Neoplasm1CTD_human
HgeneCDKN2AC0751691Perineurioma1CTD_human
HgeneCDKN2AC0751886Brain Stem Neoplasms, Primary1CTD_human
HgeneCDKN2AC0751887Medullary Neoplasms1CTD_human
HgeneCDKN2AC0751888Mesencephalic Neoplasms1CTD_human
HgeneCDKN2AC0751889Pontine Tumors1CTD_human
HgeneCDKN2AC0887833Carcinoma, Pancreatic Ductal1CTD_human
HgeneCDKN2AC1257931Mammary Neoplasms, Human1CTD_human
HgeneCDKN2AC1292769Precursor B-cell lymphoblastic leukemia1ORPHANET
HgeneCDKN2AC1297882Partial Trisomy1CTD_human
HgeneCDKN2AC1449861Micronuclei, Chromosome-Defective1CTD_human
HgeneCDKN2AC1449862Micronuclei, Genotoxicant-Induced1CTD_human
HgeneCDKN2AC1458155Mammary Neoplasms1CTD_human
HgeneCDKN2AC1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneCDKN2AC1835042Melanoma astrocytoma syndrome1CTD_human;ORPHANET
HgeneCDKN2AC1961099Precursor T-Cell Lymphoblastic Leukemia-Lymphoma1ORPHANET
HgeneCDKN2AC1961102Precursor Cell Lymphoblastic Leukemia Lymphoma1CTD_human
HgeneCDKN2AC2314896Familial Atypical Mole Melanoma Syndrome1ORPHANET
HgeneCDKN2AC2930745Partial Monosomy1CTD_human
HgeneCDKN2AC2931038Pancreatic carcinoma, familial1ORPHANET
HgeneCDKN2AC2931822Nasopharyngeal carcinoma1CTD_human
HgeneCDKN2AC4283859Cutaneous Malignant Melanoma 21GENOMICS_ENGLAND
HgeneCDKN2AC4704874Mammary Carcinoma, Human1CTD_human
HgeneCDKN2AC4721453Peripheral Nervous System Diseases1CTD_human
TgeneC0025202melanoma1CTD_human
TgeneC0027960Nevus1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC1862177Diaphyseal medullary stenosis with malignant fibrous histiocytoma1CTD_human;GENOMICS_ENGLAND;ORPHANET