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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:APPBP2-SEPT9 (FusionGDB2 ID:HG10513TG10801)

Fusion Gene Summary for APPBP2-SEPT9

check button Fusion gene summary
Fusion gene informationFusion gene name: APPBP2-SEPT9
Fusion gene ID: hg10513tg10801
HgeneTgene
Gene symbol

APPBP2

SEPT9

Gene ID

10513

10801

Gene nameamyloid beta precursor protein binding protein 2septin 9
SynonymsAPP-BP2|HS.84084|PAT1AF17q25|MSF|MSF1|NAPB|PNUTL4|SEPT9|SINT1|SeptD1
Cytomap('APPBP2')('SEPT9')

17q23.2

17q25.3

Type of geneprotein-codingprotein-coding
Descriptionamyloid protein-binding protein 2amyloid beta precursor protein (cytoplasmic tail) binding protein 2protein interacting with APP tail 1septin-9MLL septin-like fusion protein MSF-AOv/Br septinovarian/breast septinseptin D1
Modification date2020031320200328
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000083182, ENST00000592995, 
Fusion gene scores* DoF score13 X 9 X 8=93628 X 12 X 9=3024
# samples 1527
** MAII scorelog2(15/936*10)=-2.64154602908752
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/3024*10)=-3.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: APPBP2 [Title/Abstract] AND SEPT9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAPPBP2(58577760)-SEPT9(75486824), # samples:1
Anticipated loss of major functional domain due to fusion event.APPBP2-SEPT9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
APPBP2-SEPT9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
APPBP2-SEPT9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
APPBP2-SEPT9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAPPBP2

GO:0046907

intracellular transport

9843960


check buttonFusion gene breakpoints across APPBP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SEPT9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A2FS-01AAPPBP2chr17

58577760

-SEPT9chr17

75486824

+


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Fusion Gene ORF analysis for APPBP2-SEPT9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000083182ENST00000591088APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-3UTRENST00000083182ENST00000592481APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-3UTRENST00000083182ENST00000592951APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-intronENST00000083182ENST00000427180APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-intronENST00000083182ENST00000541152APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-intronENST00000083182ENST00000585930APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-intronENST00000083182ENST00000590917APPBP2chr17

58577760

-SEPT9chr17

75486824

+
5CDS-intronENST00000083182ENST00000592420APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000329047APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000423034APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000427177APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000427674APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000431235APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000449803APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000588690APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000590294APPBP2chr17

58577760

-SEPT9chr17

75486824

+
In-frameENST00000083182ENST00000591198APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000329047APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000423034APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000427177APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000427674APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000431235APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000449803APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000588690APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000590294APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3CDSENST00000592995ENST00000591198APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3UTRENST00000592995ENST00000591088APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3UTRENST00000592995ENST00000592481APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-3UTRENST00000592995ENST00000592951APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-intronENST00000592995ENST00000427180APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-intronENST00000592995ENST00000541152APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-intronENST00000592995ENST00000585930APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-intronENST00000592995ENST00000590917APPBP2chr17

58577760

-SEPT9chr17

75486824

+
intron-intronENST00000592995ENST00000592420APPBP2chr17

58577760

-SEPT9chr17

75486824

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000083182APPBP2chr1758577760-ENST00000427177SEPT9chr1775486824+2948515601013317
ENST00000083182APPBP2chr1758577760-ENST00000591198SEPT9chr1775486824+1385515601013317
ENST00000083182APPBP2chr1758577760-ENST00000449803SEPT9chr1775486824+2948515601013317
ENST00000083182APPBP2chr1758577760-ENST00000431235SEPT9chr1775486824+2952515601013317
ENST00000083182APPBP2chr1758577760-ENST00000329047SEPT9chr1775486824+2948515601013317
ENST00000083182APPBP2chr1758577760-ENST00000590294SEPT9chr1775486824+1311515601013317
ENST00000083182APPBP2chr1758577760-ENST00000588690SEPT9chr1775486824+2187515601013317
ENST00000083182APPBP2chr1758577760-ENST00000423034SEPT9chr1775486824+2950515601013317
ENST00000083182APPBP2chr1758577760-ENST00000427674SEPT9chr1775486824+2950515601013317

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000083182ENST00000427177APPBP2chr1758577760-SEPT9chr1775486824+0.0020515140.99794847
ENST00000083182ENST00000591198APPBP2chr1758577760-SEPT9chr1775486824+0.0020188240.99798125
ENST00000083182ENST00000449803APPBP2chr1758577760-SEPT9chr1775486824+0.0020515140.99794847
ENST00000083182ENST00000431235APPBP2chr1758577760-SEPT9chr1775486824+0.0020428360.9979571
ENST00000083182ENST00000329047APPBP2chr1758577760-SEPT9chr1775486824+0.0020515140.99794847
ENST00000083182ENST00000590294APPBP2chr1758577760-SEPT9chr1775486824+0.0015304240.99846953
ENST00000083182ENST00000588690APPBP2chr1758577760-SEPT9chr1775486824+0.0024448240.9975552
ENST00000083182ENST00000423034APPBP2chr1758577760-SEPT9chr1775486824+0.0020365070.99796355
ENST00000083182ENST00000427674APPBP2chr1758577760-SEPT9chr1775486824+0.0020365070.99796355

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Fusion Genomic Features for APPBP2-SEPT9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
APPBP2chr1758577759-SEPT9chr1775486823+4.11E-060.99999595
APPBP2chr1758577759-SEPT9chr1775486823+4.11E-060.99999595

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for APPBP2-SEPT9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:58577760/chr17:75486824)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427674511295_567256423.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000431235612295_567256423.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000449803612295_567256423.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000541152410295_567169336.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000585930410295_567196363.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000588690512295_567256512.6666666666666DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591088410295_567169336.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000592951410295_567169336.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000329047511445_453402569.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000423034511445_453413580.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427177612445_453420587.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427180410445_453308475.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427674511445_453256423.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000431235612445_453256423.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000449803612445_453256423.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000541152410445_453169336.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000585930410445_453196363.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000588690512445_453256512.6666666666666Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000590294512445_453402354.3333333333333Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591088410445_453169336.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591198511445_453401568.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000592951410445_453169336.0Nucleotide bindingGTP
TgeneSEPT9chr17:58577760chr17:75486824ENST00000329047511444_447402569.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000423034511444_447413580.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427177612444_447420587.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427180410362_365308475.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427180410444_447308475.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427674511305_312256423.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427674511362_365256423.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427674511444_447256423.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000431235612305_312256423.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000431235612362_365256423.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000431235612444_447256423.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000449803612305_312256423.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000449803612362_365256423.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000449803612444_447256423.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000541152410305_312169336.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000541152410362_365169336.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000541152410444_447169336.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000585930410305_312196363.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000585930410362_365196363.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000585930410444_447196363.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000588690512305_312256512.6666666666666RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000588690512362_365256512.6666666666666RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000588690512444_447256512.6666666666666RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000590294512444_447402354.3333333333333RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591088410305_312169336.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591088410362_365169336.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591088410444_447169336.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591198511444_447401568.0RegionG4 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000592951410305_312169336.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000592951410362_365169336.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000592951410444_447169336.0RegionG4 motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213120_15375586.0RepeatNote=TPR 2
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213206_23975586.0RepeatNote=TPR 3
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213288_32175586.0RepeatNote=TPR 4
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213333_36775586.0RepeatNote=TPR 5
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213429_46275586.0RepeatNote=TPR 6
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213471_50575586.0RepeatNote=TPR 7
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-21350_8375586.0RepeatNote=TPR 1
HgeneAPPBP2chr17:58577760chr17:75486824ENST00000083182-213514_54775586.0RepeatNote=TPR 8
TgeneSEPT9chr17:58577760chr17:75486824ENST00000329047511295_567402569.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000423034511295_567413580.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427177612295_567420587.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427180410295_567308475.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000590294512295_567402354.3333333333333DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591198511295_567401568.0DomainSeptin-type G
TgeneSEPT9chr17:58577760chr17:75486824ENST00000329047511305_312402569.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000329047511362_365402569.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000423034511305_312413580.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000423034511362_365413580.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427177612305_312420587.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427177612362_365420587.0RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000427180410305_312308475.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000590294512305_312402354.3333333333333RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000590294512362_365402354.3333333333333RegionG3 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591198511305_312401568.0RegionG1 motif
TgeneSEPT9chr17:58577760chr17:75486824ENST00000591198511362_365401568.0RegionG3 motif


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Fusion Gene Sequence for APPBP2-SEPT9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5661_5661_1_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000329047_length(transcript)=2948nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_1_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000329047_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_2_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000423034_length(transcript)=2950nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_2_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000423034_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_3_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000427177_length(transcript)=2948nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_3_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000427177_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_4_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000427674_length(transcript)=2950nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_4_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000427674_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_5_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000431235_length(transcript)=2952nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_5_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000431235_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_6_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000449803_length(transcript)=2948nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAGTGAGTCTGGTGGAGGAGCTGAGGGAGGGAGCC
ATGGAAGGTGCCAGAAGGAAGGTTGGCGGGGGCACGTGTGGGCCGTGGCTTGGGCTGGTCAGAGTGGCGTGAGCTGCCCGGCGCCTGCCC
TGCCCAAGTGACCAGGGAAGTGTGTGTGTGTCCATGTGTATGCGTGTCCGTCTGTCTGTCTAGTGTCTGGGTTTGGCCCAAGACTGGGCT
GTAGTTACATTAATGCCCAGCCAGCCACCCCTGCCACTCACCCTTCCTGGCCCAGGCCTTGCTGACTCTCTGAGCTGGGGAGGTGGGAGG
CCAGGCGAGCCTGACTCTGTTGATCTACCCGTGCCTGGGCCCCTCCCCTCAGAGCCCATGGTAACGAACCCCTAGAAAGGAGAGAACGGG
CGTCAGGGGTGCACAGTCCACAGCTGAAGAGCAAGGTTTCGTGGCAGCACGGCCCGGCCCCTCACCCTCTGTCCCCACGAGGGGACCCAT
GGGGGCTGTCTTTGCAGGGCACAGATGACCAAAGTCCCTTCCTGCTTCCTGTTACCTGTCTTGCTCCTGGGGAGAAAGAGGGGCCTGATG
AGACTCCACTCAGGTGCACACATCACCAGGTGCATCTGCAGGCACCGGGCTGGCTGCTTGCAGCCAGGAGAAGGTCAGCGAGAAGGAGTG
TATGAGTGTGAGTGTGTGTGCATGGAAGTTGGGGCACTGGGCGTCTGACTCCCTCCCCACCCAAGAGAGGAAGGACCCCTCACCACCCCC
ACTGGTGAGACAGTTTACTTTGCCAACTTGCCATGTTTTTGCCAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGG
CCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGTGGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTC
CTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGT

>5661_5661_6_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000449803_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_7_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000588690_length(transcript)=2187nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC
TCAGTGCCGGAGGCCTTGGGGTGGGGGCCAGGCCTCGCACTTGCAGAGGAGCCCAGTGGGCTGCACGCTCCCCTCCATCCCCATCGGCCC
TGTCCCCTGGAGTGTGTCAGAGCCCAGGGGAGAATGCAGCCCACCAGGAGCACCTGGACCCCCTGCCCGCCACATGGTGTGGCCATCACT
CAGCCCCTACCCCTGCCCTGCTCCTAAGGGTAGAAAACTCCAGGGTCCCCTGCCACCGACTGCCCAGCCACTCCAAGCCCCCTGGCAGCT
GCCCCTCCTGGAGCAGAAAGTGCCTTTATCTCAGCCATCCGCAGACTGCTTGGCCAGATGCGGGGACAGGCTGGAATGAGGGAGGCGTCT
TCATCTCCCTGCCATCCCCCTCTCACGCCACCCCCGCCCCCACCGGGCTGCAGGTGCTGCTGATGCGCTGGGATCTGATTGAGGATAAAA
AGGAAGGAGAGATGACCCCTACCCCCTCATCCCCCAGTTTTGAAAAGGTCTAAGCAAACAGTTTACTTTGCCAACTTGCCATGTTTTTGC
CAAAACCAAGATTTTGAAGGAAATGAGTGGCCAGCGCCAGGGCCCAGGCCATGTGGCCTGCCCAGCCTCAATGTCACTTGGTGGCGGGGT
GGGGTGGGGGTGGGCAGCAGCATCCCAGCCTTGAGATGCTTCACTTTCCTTCTCTGTAACCAGACTTTGAAAAATTGTTCGTTTCATCAG
GCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGTCTTTTTGTATAAATGACAAAGTGTTGAAAATGTATTTCCTGA

>5661_5661_7_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000588690_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_8_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000590294_length(transcript)=1311nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCCATCCCAGCCTTGAGATGCTTCACTTTCCTTCTCTGTAACCAGACTTTG
AAAAATTGTTCGTTTCATCAGGCTCTGTTCCTCAATGGCCTTTTGCTACGTGCCTCCCGAGAAATTTGTCTTTTTGTATAAATGACAAAG

>5661_5661_8_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000590294_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------
>5661_5661_9_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000591198_length(transcript)=1385nt_BP=515nt
GAGATCAGCGCTGGGACGGAACCCGGGTTCCTCTCGAACCGGGATTGTGACGCTTTTGGCCTGGCTGGCCGCTGTTTTCTGTCCCACTTT
TTACTCGGGCCTGCGTCCGCTGCCGCCGTCCCTCAGTTTGCCCCCGGAGGAGGCAGGGCGGCCGTGCCTTCTGCCGTGCGCCCGCGTGGC
TGCCACCGCCCCTCCGAATCCTCCGGGGCCGCAGAGGGGTTCGCTACGGAGGGAGGTGGGGGCCTTCGGGAGGAGGAGGCGGAGGAGGCG
GAGGAGGAGGGAAGGAAGATGGCGGCCGTGGAACTAGAGTGGATCCCAGAGACTCTCTATAACACCGCCATCTCCGCTGTCGTGGACAAC
TACATCCGCTCCCGCCGAGACATCCGCTCCTTGCCCGAGAACATCCAGTTTGATGTTTACTACAAGCTTTACCAACAGGGACGCTTATGT
CAACTGGGCAGTGAATTTTGTGAATTGGAAGTTTTTGCTAAAGTACTGAGAGCTTTGGATAAAAGCCTCAGGCCCCTGGACATCGAGTTT
ATGAAACGCCTGAGCAAGGTGGTCAACATCGTCCCTGTCATCGCCAAGGCGGACACACTCACCCTGGAGGAGAGGGTCCACTTCAAACAG
CGGATCACCGCAGACCTGCTGTCCAACGGCATCGACGTGTACCCCCAGAAGGAATTTGATGAGGACTCGGAGGACCGGCTGGTGAACGAG
AAGTTCCGGGAGATGATCCCATTTGCTGTGGTGGGCAGTGACCACGAGTACCAGGTCAACGGCAAGAGGATCCTTGGGAGGAAGACCAAG
TGGGGTACCATCGAAGTTGAAAACACCACACACTGTGAGTTTGCCTACCTGCGGGACCTTCTCATCAGGACGCACATGCAGAACATCAAG
GACATCACCAGCAGCATCCACTTCGAGGCGTACCGTGTGAAGCGCCTCAACGAGGGCAGCAGCGCCATGGCCAACGGCATGGAGGAGAAG
GAGCCAGAAGCCCCGGAGATGTAGACGCCACCCTGCCCACCCCCGGGATCCTGCCCCCAAGTCATTTCCGTCCCCCCCCAGGCCCTCCCA
CCACCCCATTTTATTTTATATGATTTTCTCCATTTGTCATCGTTCCCCACCCCTTCGACATGCTGCCAGGAAACAAGGGAAGGGGCCTCC
CTCCGAGTGAGTCAGTGATGAGGCCGCGGCCTCCCCGAGGTTGTGGGGAGGCTGCACTGGAGCCACAGGCAGGGGTGAGAGCACCCACTG
AATTGACATGACCCTCTGTCCCCAGGCCTGGCTCCCCGAGGGCTCAGAAGAGCAGCTTCGGTGTGCAGATCATCCGTCTGTGTGGGGTTC

>5661_5661_9_APPBP2-SEPT9_APPBP2_chr17_58577760_ENST00000083182_SEPT9_chr17_75486824_ENST00000591198_length(amino acids)=317AA_BP=151
MAGRCFLSHFLLGPASAAAVPQFAPGGGRAAVPSAVRPRGCHRPSESSGAAEGFATEGGGGLREEEAEEAEEEGRKMAAVELEWIPETLY
NTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEFCELEVFAKVLRALDKSLRPLDIEFMKRLSKVVNIVPVIAKADTL
TLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for APPBP2-SEPT9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for APPBP2-SEPT9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for APPBP2-SEPT9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource