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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARFGEF1-CPA6 (FusionGDB2 ID:HG10565TG57094)

Fusion Gene Summary for ARFGEF1-CPA6

check button Fusion gene summary
Fusion gene informationFusion gene name: ARFGEF1-CPA6
Fusion gene ID: hg10565tg57094
HgeneTgene
Gene symbol

ARFGEF1

CPA6

Gene ID

10565

57094

Gene nameADP ribosylation factor guanine nucleotide exchange factor 1carboxypeptidase A6
SynonymsARFGEP1|BIG1|P200CPAH|ETL5|FEB11
Cytomap('ARFGEF1')('CPA6')

8q13.2

8q13.2

Type of geneprotein-codingprotein-coding
Descriptionbrefeldin A-inhibited guanine nucleotide-exchange protein 1ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)p200 ARF guanine nucleotide exchange factorcarboxypeptidase A6carboxypeptidase B
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000262215, ENST00000520381, 
ENST00000517955, ENST00000518230, 
Fusion gene scores* DoF score14 X 14 X 6=11767 X 9 X 5=315
# samples 179
** MAII scorelog2(17/1176*10)=-2.79028140869866
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/315*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARFGEF1 [Title/Abstract] AND CPA6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARFGEF1(68255399)-CPA6(68334926), # samples:2
Anticipated loss of major functional domain due to fusion event.ARFGEF1-CPA6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARFGEF1-CPA6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARFGEF1-CPA6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARFGEF1-CPA6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARFGEF1-CPA6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARFGEF1-CPA6 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARFGEF1

GO:0034260

negative regulation of GTPase activity

15644318


check buttonFusion gene breakpoints across ARFGEF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CPA6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A09N-01AARFGEF1chr8

68150970

-CPA6chr8

68397024

-
ChimerDB4BRCATCGA-E2-A14Y-01AARFGEF1chr8

68255399

-CPA6chr8

68334926

-


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Fusion Gene ORF analysis for ARFGEF1-CPA6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000262215ENST00000518549ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
Frame-shiftENST00000262215ENST00000297769ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
Frame-shiftENST00000262215ENST00000297770ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
In-frameENST00000262215ENST00000297769ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
In-frameENST00000262215ENST00000297770ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
In-frameENST00000262215ENST00000518549ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
In-frameENST00000520381ENST00000297769ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
In-frameENST00000520381ENST00000297770ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
In-frameENST00000520381ENST00000518549ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000517955ENST00000297769ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000517955ENST00000297769ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-3CDSENST00000517955ENST00000297770ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000517955ENST00000297770ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-3CDSENST00000517955ENST00000518549ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000518230ENST00000297769ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000518230ENST00000297769ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-3CDSENST00000518230ENST00000297770ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000518230ENST00000297770ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-3CDSENST00000518230ENST00000518549ARFGEF1chr8

68150970

-CPA6chr8

68397024

-
intron-3CDSENST00000520381ENST00000297769ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-3CDSENST00000520381ENST00000297770ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-intronENST00000517955ENST00000518549ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-intronENST00000518230ENST00000518549ARFGEF1chr8

68255399

-CPA6chr8

68334926

-
intron-intronENST00000520381ENST00000518549ARFGEF1chr8

68255399

-CPA6chr8

68334926

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000520381ARFGEF1chr868150970-ENST00000297769CPA6chr868397024-22921568321957641
ENST00000520381ARFGEF1chr868150970-ENST00000297770CPA6chr868397024-25771568322245737
ENST00000520381ARFGEF1chr868150970-ENST00000518549CPA6chr868397024-22561568321879615
ENST00000262215ARFGEF1chr868150970-ENST00000297769CPA6chr868397024-4252352839039171175
ENST00000262215ARFGEF1chr868150970-ENST00000297770CPA6chr868397024-4537352839042051271
ENST00000262215ARFGEF1chr868150970-ENST00000518549CPA6chr868397024-4216352839038391149

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000520381ENST00000297769ARFGEF1chr868150970-CPA6chr868397024-0.0006411090.99935895
ENST00000520381ENST00000297770ARFGEF1chr868150970-CPA6chr868397024-0.0006389410.9993611
ENST00000520381ENST00000518549ARFGEF1chr868150970-CPA6chr868397024-0.0006918280.9993082
ENST00000262215ENST00000297769ARFGEF1chr868150970-CPA6chr868397024-0.0006633150.99933666
ENST00000262215ENST00000297770ARFGEF1chr868150970-CPA6chr868397024-0.0006560990.99934393
ENST00000262215ENST00000518549ARFGEF1chr868150970-CPA6chr868397024-0.0005145810.9994854

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Fusion Genomic Features for ARFGEF1-CPA6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARFGEF1-CPA6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:68255399/chr8:68334926)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARFGEF1chr8:68150970chr8:68397024ENST00000262215-2139709_84010461850.0DomainSEC7
HgeneARFGEF1chr8:68150970chr8:68397024ENST00000262215-2139711_71510461850.0MotifNote=Nuclear localization signal (NLS)
TgeneCPA6chr8:68150970chr8:68397024ENST0000029776959196_19964194.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST0000029776959271_27264194.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST0000029776959325_32664194.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST00000297770511271_272212438.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST00000297770511325_326212438.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST0000051854958271_272212316.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST0000051854958325_326212316.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCPA6chr8:68150970chr8:68397024ENST00000297770511196_199212438.0RegionSubstrate binding
TgeneCPA6chr8:68150970chr8:68397024ENST0000051854958196_199212316.0RegionSubstrate binding


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Fusion Gene Sequence for ARFGEF1-CPA6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5850_5850_1_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000297769_length(transcript)=4252nt_BP=3528nt
GCGGTGCCTCTGAGAGCCGCCGCCACCTCGTCCCTCAGTTCCCGGCAGACAGCCGCCCGGGCCGGGCTCCCTCACCGCCACCAGGGCCGG
AGGGACGAGTGAGAGGGGCGGCCGGGACGCGACCCCCGGGCCGGGAGAAGCGGAGGCCCGACGGGCGCGGCCCTCGAGGTACGGCTTCTT
GGGGGCGGCGAGGACCTCGACGCCCTTCGCCGACACCGCGGCTGGTCCCGCTCGCCCGCCCCTTCCTGATCCTGCCGCTGCCCTCCACGC
CTCCAATCCCCCACCTCCACCCCCTCTCCTTTCTCTCTTCTCTTCCTTCCTCTCCTCCTCCTCCCCTCCAGCCGCTGGGAGCCGCGGGTC
GGACGAGCCGCCGCCTCCTTCTCTGCGTCCATGTATGAGGGGAAGAAGACGAAGAACATGTTCCTGACCCGGGCTCTGGAGAAGATATTG
GCCGACAAGGAAGTGAAGAAGGCGCATCACTCCCAGCTGCGCAAAGCTTGCGAGGTGGCGTTAGAGGAAATAAAAGCGGAAACTGAAAAA
CAGAGTCCTCCTCATGGAGAAGCAAAAGCTGGATCAAGCACCCTTCCACCAGTGAAATCAAAGACAAATTTTATTGAAGCAGACAAGTAC
TTCTTGCCTTTTGAGTTGGCATGCCAGTCCAAATGTCCTCGCATAGTTAGTACATCTCTAGATTGCTTACAGAAACTTATTGCTTATGGG
CACTTGACTGGCAATGCTCCAGATAGTACAACACCAGGCAAAAAATTAATTGATAGAATTATTGAAACAATATGTGGCTGCTTTCAGGGC
CCTCAGACAGATGAAGGAGTTCAGCTGCAGATAATAAAGGCTTTACTTACTGCAGTAACATCACAACACATAGAAATTCATGAAGGGACT
GTACTGCAAGCTGTGAGAACATGTTACAATATCTACTTAGCAAGCAAAAATCTCATCAATCAGACAACAGCCAAAGCTACTCTCACTCAG
ATGCTAAATGTTATCTTTGCACGCATGGAAAACCAAGCATTACAGGAAGCAAAACAAATGGAAAAAGAAAGGCATCGGCAGCATCATCAT
CTGTTACAGTCTCCAGTAAGCCATCACGAGCCTGAATCACCTCAACTTAGATATTTGCCACCTCAGACTGTTGATCATATATCCCAAGAA
CACGAAGGGGACCTTGACCTCCATACAAATGATGTAGATAAAAGTCTTCAGGATGACACAGAGCCTGAAAATGGATCTGATATTTCCAGT
GCAGAAAATGAACAGACTGAAGCTGATCAGGCAACTGCAGCTGAAACATTATCTAAAAATGAAGTGTTATATGACGGAGAAAACCATGAT
TGTGAGGAAAAGCCACAAGACATTGTACAGAACATTGTAGAAGAAATGGTGAACATTGTTGTTGGAGATATGGGAGAAGGGACTACTATA
AATGCAAGTGCAGATGGCAACATTGGAACTATAGAGGATGGTAGTGACAGTGAAAATATTCAAGCAAATGGAATTCCAGGAACACCAATT
TCTGTTGCATATACACCATCCTTACCTGATGATAGATTGTCAGTCTCTTCCAATGATACTCAGGAATCTGGAAATTCTTCAGGACCTTCA
CCTGGTGCTAAGTTTTCCCACATTTTACAAAAGGATGCCTTTCTAGTATTCAGGTCATTGTGTAAACTGTCAATGAAACCACTGTCAGAT
GGACCACCAGATCCAAAGTCTCATGAACTACGATCCAAGATTCTTTCATTGCAGTTACTTCTATCCATTCTGCAGAATGCAGGACCTATT
TTCAGGACAAATGAGATGTTTATTAATGCTATTAAGCAGTATCTTTGTGTTGCACTCTCAAAAAATGGAGTCTCATCTGTTCCAGAGGTT
TTTGAGCTTTCTCTTTCTATATTTCTTACTTTGTTGTCAAATTTCAAGACACATCTGAAGATGCAAATTGAGGTGTTCTTTAAAGAAATT
TTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGAGGATTTGTGCAGATGCTCAG
AGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAAATGATCTATCAAAAATTGCT
CAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAGAATGCTTAGTGTCGATTTTG
AAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAAAACCCTCAGAGCAAGAGATG
AGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCATCAGGAATAGGCAGCTACAGT
ACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAACAAGGGATAGATTTATTTAAT
AAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTGCCCAATTCTTACATCAAGAG
GAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGTATGCATATGTGGACCAACAT
GACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAGCTCAGAAAATCGATCGATTA
ATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAGCTTATGTTTTGGCTTATTCA
ATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTAAGATGAATAGAGGTATCAAT
GACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAATGAAAGAAACAAAAGAACTA
ACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAGAAATGGAGCAGATGGCCAAG
ACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGCATGTGAGGCCCATGTTTAAG
TTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCTCTCTTTGCCTGGAAGGTATA
AGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAGCAAGATTTACCTTACTCACA
GTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTCATACAGATGGAAATTATTTA
GGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATCTATATTTCTATATCATGCCT
GTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGAACTCAAGGTTTCGCTGCCGT
GGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGATGTGAGCTCTGGTAGCTCAATGGATTGGGCCTACAAAAATGGAATACCT
TATGCATTTGCTTTCGAACTACGTGACACTGGATATTTTGGATTTTTACTCCCAGAGATGCTCATCAAACCCACCTGTACAGAAACTATG
CTGGCTGTGAAAAATATCACAATGCACCTGCTAAAGAAATGTCCCTGAGACAGCCCAAGGCTCAGGTCAACTGCCATAGGATTCTGAGCA
AGGCCTACTTGGCCCTGGATAGAAATTGTTTTCAAAGAGAAGGGCAGCTGCTTAGAGTGAACATGTCTATGGACTTTAAAAAGACCCCAC
GCAATTTGACTTTGTGGCAATAGAAAACAGTAAAAAACAGGGCATAGCCTAGTTTGTTATAAGAAAAAGCATCCATTTTCTATCCTTTTA
GAGTCTTATTTGATTATGGTGGGAGGGAATGTTTTCAAATTTCCCATTTCTCAAGAAATGTTCATATTAATTGAGGATTTCCCTTCAATA
AATCTCATGTCCTCAATTAGGA

>5850_5850_1_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000297769_length(amino acids)=1175AA_BP=1046
MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKSKTNFIEADKYFLPFELACQS
KCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYN
IYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTN
DVDKSLQDDTEPENGSDISSAENEQTEADQATAAETLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT
IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHEL
RSKILSLQLLLSILQNAGPIFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTS
SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQ
YVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYL
QEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLE
CNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQN
VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIF
SIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFS
WTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHL
LKKCP

--------------------------------------------------------------
>5850_5850_2_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000297770_length(transcript)=4537nt_BP=3528nt
GCGGTGCCTCTGAGAGCCGCCGCCACCTCGTCCCTCAGTTCCCGGCAGACAGCCGCCCGGGCCGGGCTCCCTCACCGCCACCAGGGCCGG
AGGGACGAGTGAGAGGGGCGGCCGGGACGCGACCCCCGGGCCGGGAGAAGCGGAGGCCCGACGGGCGCGGCCCTCGAGGTACGGCTTCTT
GGGGGCGGCGAGGACCTCGACGCCCTTCGCCGACACCGCGGCTGGTCCCGCTCGCCCGCCCCTTCCTGATCCTGCCGCTGCCCTCCACGC
CTCCAATCCCCCACCTCCACCCCCTCTCCTTTCTCTCTTCTCTTCCTTCCTCTCCTCCTCCTCCCCTCCAGCCGCTGGGAGCCGCGGGTC
GGACGAGCCGCCGCCTCCTTCTCTGCGTCCATGTATGAGGGGAAGAAGACGAAGAACATGTTCCTGACCCGGGCTCTGGAGAAGATATTG
GCCGACAAGGAAGTGAAGAAGGCGCATCACTCCCAGCTGCGCAAAGCTTGCGAGGTGGCGTTAGAGGAAATAAAAGCGGAAACTGAAAAA
CAGAGTCCTCCTCATGGAGAAGCAAAAGCTGGATCAAGCACCCTTCCACCAGTGAAATCAAAGACAAATTTTATTGAAGCAGACAAGTAC
TTCTTGCCTTTTGAGTTGGCATGCCAGTCCAAATGTCCTCGCATAGTTAGTACATCTCTAGATTGCTTACAGAAACTTATTGCTTATGGG
CACTTGACTGGCAATGCTCCAGATAGTACAACACCAGGCAAAAAATTAATTGATAGAATTATTGAAACAATATGTGGCTGCTTTCAGGGC
CCTCAGACAGATGAAGGAGTTCAGCTGCAGATAATAAAGGCTTTACTTACTGCAGTAACATCACAACACATAGAAATTCATGAAGGGACT
GTACTGCAAGCTGTGAGAACATGTTACAATATCTACTTAGCAAGCAAAAATCTCATCAATCAGACAACAGCCAAAGCTACTCTCACTCAG
ATGCTAAATGTTATCTTTGCACGCATGGAAAACCAAGCATTACAGGAAGCAAAACAAATGGAAAAAGAAAGGCATCGGCAGCATCATCAT
CTGTTACAGTCTCCAGTAAGCCATCACGAGCCTGAATCACCTCAACTTAGATATTTGCCACCTCAGACTGTTGATCATATATCCCAAGAA
CACGAAGGGGACCTTGACCTCCATACAAATGATGTAGATAAAAGTCTTCAGGATGACACAGAGCCTGAAAATGGATCTGATATTTCCAGT
GCAGAAAATGAACAGACTGAAGCTGATCAGGCAACTGCAGCTGAAACATTATCTAAAAATGAAGTGTTATATGACGGAGAAAACCATGAT
TGTGAGGAAAAGCCACAAGACATTGTACAGAACATTGTAGAAGAAATGGTGAACATTGTTGTTGGAGATATGGGAGAAGGGACTACTATA
AATGCAAGTGCAGATGGCAACATTGGAACTATAGAGGATGGTAGTGACAGTGAAAATATTCAAGCAAATGGAATTCCAGGAACACCAATT
TCTGTTGCATATACACCATCCTTACCTGATGATAGATTGTCAGTCTCTTCCAATGATACTCAGGAATCTGGAAATTCTTCAGGACCTTCA
CCTGGTGCTAAGTTTTCCCACATTTTACAAAAGGATGCCTTTCTAGTATTCAGGTCATTGTGTAAACTGTCAATGAAACCACTGTCAGAT
GGACCACCAGATCCAAAGTCTCATGAACTACGATCCAAGATTCTTTCATTGCAGTTACTTCTATCCATTCTGCAGAATGCAGGACCTATT
TTCAGGACAAATGAGATGTTTATTAATGCTATTAAGCAGTATCTTTGTGTTGCACTCTCAAAAAATGGAGTCTCATCTGTTCCAGAGGTT
TTTGAGCTTTCTCTTTCTATATTTCTTACTTTGTTGTCAAATTTCAAGACACATCTGAAGATGCAAATTGAGGTGTTCTTTAAAGAAATT
TTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGAGGATTTGTGCAGATGCTCAG
AGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAAATGATCTATCAAAAATTGCT
CAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAGAATGCTTAGTGTCGATTTTG
AAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAAAACCCTCAGAGCAAGAGATG
AGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCATCAGGAATAGGCAGCTACAGT
ACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAACAAGGGATAGATTTATTTAAT
AAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTGCCCAATTCTTACATCAAGAG
GAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGTATGCATATGTGGACCAACAT
GACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAGCTCAGAAAATCGATCGATTA
ATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAGCTTATGTTTTGGCTTATTCA
ATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTAAGATGAATAGAGGTATCAAT
GACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAATGAAAGAAACAAAAGAACTA
ACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAGAAATGGAGCAGATGGCCAAG
ACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGCATGTGAGGCCCATGTTTAAG
TTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCTCTCTTTGCCTGGAAGGTATA
AGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAGCAAGATTTACCTTACTCACA
GTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTCATACAGATGGAAATTATTTA
GGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATCTATATTTCTATATCATGCCT
GTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGAACTCAAGGTTTCGCTGCCGT
GGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGATGAAGGAGCTTCTATGCACCCTTGTGATGACACATACTGTGGCCCTTTT
CCAGAATCTGAGCCGGAAGTGAAGGCTGTAGCTAACTTCCTTCGAAAACACAGAAAGCACATTAGGGCTTATCTCTCCTTTCATGCATAT
GCTCAGATGTTACTGTATCCCTATTCTTACAAATATGCAACAATTCCCAATTTTAGATGTGTGGAATCTGCAGCTTATAAAGCTGTGAAT
GCACTTCAGTCAGTATACGGGGTACGATACAGATATGGACCAGCCTCCACAACGTTGTATGTGAGCTCTGGTAGCTCAATGGATTGGGCC
TACAAAAATGGAATACCTTATGCATTTGCTTTCGAACTACGTGACACTGGATATTTTGGATTTTTACTCCCAGAGATGCTCATCAAACCC
ACCTGTACAGAAACTATGCTGGCTGTGAAAAATATCACAATGCACCTGCTAAAGAAATGTCCCTGAGACAGCCCAAGGCTCAGGTCAACT
GCCATAGGATTCTGAGCAAGGCCTACTTGGCCCTGGATAGAAATTGTTTTCAAAGAGAAGGGCAGCTGCTTAGAGTGAACATGTCTATGG
ACTTTAAAAAGACCCCACGCAATTTGACTTTGTGGCAATAGAAAACAGTAAAAAACAGGGCATAGCCTAGTTTGTTATAAGAAAAAGCAT
CCATTTTCTATCCTTTTAGAGTCTTATTTGATTATGGTGGGAGGGAATGTTTTCAAATTTCCCATTTCTCAAGAAATGTTCATATTAATT
GAGGATTTCCCTTCAATAAATCTCATGTCCTCAATTA

>5850_5850_2_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000297770_length(amino acids)=1271AA_BP=1046
MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKSKTNFIEADKYFLPFELACQS
KCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYN
IYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTN
DVDKSLQDDTEPENGSDISSAENEQTEADQATAAETLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT
IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHEL
RSKILSLQLLLSILQNAGPIFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTS
SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQ
YVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYL
QEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLE
CNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQN
VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIF
SIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFS
WTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSY
KYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVK
NITMHLLKKCP

--------------------------------------------------------------
>5850_5850_3_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000518549_length(transcript)=4216nt_BP=3528nt
GCGGTGCCTCTGAGAGCCGCCGCCACCTCGTCCCTCAGTTCCCGGCAGACAGCCGCCCGGGCCGGGCTCCCTCACCGCCACCAGGGCCGG
AGGGACGAGTGAGAGGGGCGGCCGGGACGCGACCCCCGGGCCGGGAGAAGCGGAGGCCCGACGGGCGCGGCCCTCGAGGTACGGCTTCTT
GGGGGCGGCGAGGACCTCGACGCCCTTCGCCGACACCGCGGCTGGTCCCGCTCGCCCGCCCCTTCCTGATCCTGCCGCTGCCCTCCACGC
CTCCAATCCCCCACCTCCACCCCCTCTCCTTTCTCTCTTCTCTTCCTTCCTCTCCTCCTCCTCCCCTCCAGCCGCTGGGAGCCGCGGGTC
GGACGAGCCGCCGCCTCCTTCTCTGCGTCCATGTATGAGGGGAAGAAGACGAAGAACATGTTCCTGACCCGGGCTCTGGAGAAGATATTG
GCCGACAAGGAAGTGAAGAAGGCGCATCACTCCCAGCTGCGCAAAGCTTGCGAGGTGGCGTTAGAGGAAATAAAAGCGGAAACTGAAAAA
CAGAGTCCTCCTCATGGAGAAGCAAAAGCTGGATCAAGCACCCTTCCACCAGTGAAATCAAAGACAAATTTTATTGAAGCAGACAAGTAC
TTCTTGCCTTTTGAGTTGGCATGCCAGTCCAAATGTCCTCGCATAGTTAGTACATCTCTAGATTGCTTACAGAAACTTATTGCTTATGGG
CACTTGACTGGCAATGCTCCAGATAGTACAACACCAGGCAAAAAATTAATTGATAGAATTATTGAAACAATATGTGGCTGCTTTCAGGGC
CCTCAGACAGATGAAGGAGTTCAGCTGCAGATAATAAAGGCTTTACTTACTGCAGTAACATCACAACACATAGAAATTCATGAAGGGACT
GTACTGCAAGCTGTGAGAACATGTTACAATATCTACTTAGCAAGCAAAAATCTCATCAATCAGACAACAGCCAAAGCTACTCTCACTCAG
ATGCTAAATGTTATCTTTGCACGCATGGAAAACCAAGCATTACAGGAAGCAAAACAAATGGAAAAAGAAAGGCATCGGCAGCATCATCAT
CTGTTACAGTCTCCAGTAAGCCATCACGAGCCTGAATCACCTCAACTTAGATATTTGCCACCTCAGACTGTTGATCATATATCCCAAGAA
CACGAAGGGGACCTTGACCTCCATACAAATGATGTAGATAAAAGTCTTCAGGATGACACAGAGCCTGAAAATGGATCTGATATTTCCAGT
GCAGAAAATGAACAGACTGAAGCTGATCAGGCAACTGCAGCTGAAACATTATCTAAAAATGAAGTGTTATATGACGGAGAAAACCATGAT
TGTGAGGAAAAGCCACAAGACATTGTACAGAACATTGTAGAAGAAATGGTGAACATTGTTGTTGGAGATATGGGAGAAGGGACTACTATA
AATGCAAGTGCAGATGGCAACATTGGAACTATAGAGGATGGTAGTGACAGTGAAAATATTCAAGCAAATGGAATTCCAGGAACACCAATT
TCTGTTGCATATACACCATCCTTACCTGATGATAGATTGTCAGTCTCTTCCAATGATACTCAGGAATCTGGAAATTCTTCAGGACCTTCA
CCTGGTGCTAAGTTTTCCCACATTTTACAAAAGGATGCCTTTCTAGTATTCAGGTCATTGTGTAAACTGTCAATGAAACCACTGTCAGAT
GGACCACCAGATCCAAAGTCTCATGAACTACGATCCAAGATTCTTTCATTGCAGTTACTTCTATCCATTCTGCAGAATGCAGGACCTATT
TTCAGGACAAATGAGATGTTTATTAATGCTATTAAGCAGTATCTTTGTGTTGCACTCTCAAAAAATGGAGTCTCATCTGTTCCAGAGGTT
TTTGAGCTTTCTCTTTCTATATTTCTTACTTTGTTGTCAAATTTCAAGACACATCTGAAGATGCAAATTGAGGTGTTCTTTAAAGAAATT
TTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGAGGATTTGTGCAGATGCTCAG
AGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAAATGATCTATCAAAAATTGCT
CAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAGAATGCTTAGTGTCGATTTTG
AAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAAAACCCTCAGAGCAAGAGATG
AGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCATCAGGAATAGGCAGCTACAGT
ACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAACAAGGGATAGATTTATTTAAT
AAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTGCCCAATTCTTACATCAAGAG
GAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGTATGCATATGTGGACCAACAT
GACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAGCTCAGAAAATCGATCGATTA
ATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAGCTTATGTTTTGGCTTATTCA
ATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTAAGATGAATAGAGGTATCAAT
GACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAATGAAAGAAACAAAAGAACTA
ACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAGAAATGGAGCAGATGGCCAAG
ACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGCATGTGAGGCCCATGTTTAAG
TTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCTCTCTTTGCCTGGAAGGTATA
AGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAGCAAGATTTACCTTACTCACA
GTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTCATACAGATGGAAATTATTTA
GGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATCTATATTTCTATATCATGCCT
GTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGAACTCAAGGTTTCGCTGCCGT
GGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGGTAAGTTTGGGACCAACTGGGATCCAGATCCAAAGGTTTCTGCAGGTTTT
ACTCTGCAAAATATGAGTCCAGAGGACTCTCATGGGAGACTCATGTTTTTCTGTATGTGAAAACCTGGTAGAGAAAGGTACAGATACGTA
CATGATAGCTGTAATTGGCAAAAGAAAATGAAAGGATTCTTTTTTAATATATAAAAATCAAGGATTTTAAATATGTCAATTCGGTCCTGA
AAACTGAAAATTTAAATACATATGTAAAAGCAGCAAACTGAGGAATATTTGTCATTCCCCAAATTAAAACATGAACCGTGGTGTAGTATA
ATTCTGGTTAAATCTTTTTATCCTTTTCATACAAGCACCACTGATGCTGCATTCGGCTGTCTGTCGTGGTCAGAGCTGTCATGACCTTGT
CTATATTCTACCACTCTGCTGGTCATACGTGGATTGACCATGCACATTGGGAATGTATTTCTGCTGCATTCCATGT

>5850_5850_3_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000262215_CPA6_chr8_68397024_ENST00000518549_length(amino acids)=1149AA_BP=1046
MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKSKTNFIEADKYFLPFELACQS
KCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYN
IYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTN
DVDKSLQDDTEPENGSDISSAENEQTEADQATAAETLSKNEVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGT
IEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHEL
RSKILSLQLLLSILQNAGPIFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTS
SFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQ
YVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYL
QEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLE
CNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQN
VASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIF
SIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFS
WTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCGKFGTNWDPDPKVSAGFTLQNMSPEDSHGRLMFFCM

--------------------------------------------------------------
>5850_5850_4_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000297769_length(transcript)=2292nt_BP=1568nt
AGGTGTTCTTTAAAGAAATTTTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGA
GGATTTGTGCAGATGCTCAGAGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAA
ATGATCTATCAAAAATTGCTCAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAG
AATGCTTAGTGTCGATTTTGAAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAA
AACCCTCAGAGCAAGAGATGAGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCAT
CAGGAATAGGCAGCTACAGTACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAAC
AAGGGATAGATTTATTTAATAAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTG
CCCAATTCTTACATCAAGAGGAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGT
ATGCATATGTGGACCAACATGACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAG
CTCAGAAAATCGATCGATTAATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAG
CTTATGTTTTGGCTTATTCAATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTA
AGATGAATAGAGGTATCAATGACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAA
TGAAAGAAACAAAAGAACTAACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAG
AAATGGAGCAGATGGCCAAGACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGC
ATGTGAGGCCCATGTTTAAGTTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCT
CTCTTTGCCTGGAAGGTATAAGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAG
CAAGATTTACCTTACTCACAGTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTC
ATACAGATGGAAATTATTTAGGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATC
TATATTTCTATATCATGCCTGTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGA
ACTCAAGGTTTCGCTGCCGTGGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGATGTGAGCTCTGGTAGCTCAATGGATTGGG
CCTACAAAAATGGAATACCTTATGCATTTGCTTTCGAACTACGTGACACTGGATATTTTGGATTTTTACTCCCAGAGATGCTCATCAAAC
CCACCTGTACAGAAACTATGCTGGCTGTGAAAAATATCACAATGCACCTGCTAAAGAAATGTCCCTGAGACAGCCCAAGGCTCAGGTCAA
CTGCCATAGGATTCTGAGCAAGGCCTACTTGGCCCTGGATAGAAATTGTTTTCAAAGAGAAGGGCAGCTGCTTAGAGTGAACATGTCTAT
GGACTTTAAAAAGACCCCACGCAATTTGACTTTGTGGCAATAGAAAACAGTAAAAAACAGGGCATAGCCTAGTTTGTTATAAGAAAAAGC
ATCCATTTTCTATCCTTTTAGAGTCTTATTTGATTATGGTGGGAGGGAATGTTTTCAAATTTCCCATTTCTCAAGAAATGTTCATATTAA
TTGAGGATTTCCCTTCAATAAATCTCATGTCCTCAATTAGGA

>5850_5850_4_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000297769_length(amino acids)=641AA_BP=512
METSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMV
EWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPK
RGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKF
AARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPT
KSSKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAI
RIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNV
DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVK
NITMHLLKKCP

--------------------------------------------------------------
>5850_5850_5_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000297770_length(transcript)=2577nt_BP=1568nt
AGGTGTTCTTTAAAGAAATTTTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGA
GGATTTGTGCAGATGCTCAGAGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAA
ATGATCTATCAAAAATTGCTCAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAG
AATGCTTAGTGTCGATTTTGAAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAA
AACCCTCAGAGCAAGAGATGAGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCAT
CAGGAATAGGCAGCTACAGTACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAAC
AAGGGATAGATTTATTTAATAAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTG
CCCAATTCTTACATCAAGAGGAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGT
ATGCATATGTGGACCAACATGACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAG
CTCAGAAAATCGATCGATTAATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAG
CTTATGTTTTGGCTTATTCAATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTA
AGATGAATAGAGGTATCAATGACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAA
TGAAAGAAACAAAAGAACTAACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAG
AAATGGAGCAGATGGCCAAGACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGC
ATGTGAGGCCCATGTTTAAGTTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCT
CTCTTTGCCTGGAAGGTATAAGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAG
CAAGATTTACCTTACTCACAGTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTC
ATACAGATGGAAATTATTTAGGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATC
TATATTTCTATATCATGCCTGTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGA
ACTCAAGGTTTCGCTGCCGTGGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGATGAAGGAGCTTCTATGCACCCTTGTGATG
ACACATACTGTGGCCCTTTTCCAGAATCTGAGCCGGAAGTGAAGGCTGTAGCTAACTTCCTTCGAAAACACAGAAAGCACATTAGGGCTT
ATCTCTCCTTTCATGCATATGCTCAGATGTTACTGTATCCCTATTCTTACAAATATGCAACAATTCCCAATTTTAGATGTGTGGAATCTG
CAGCTTATAAAGCTGTGAATGCACTTCAGTCAGTATACGGGGTACGATACAGATATGGACCAGCCTCCACAACGTTGTATGTGAGCTCTG
GTAGCTCAATGGATTGGGCCTACAAAAATGGAATACCTTATGCATTTGCTTTCGAACTACGTGACACTGGATATTTTGGATTTTTACTCC
CAGAGATGCTCATCAAACCCACCTGTACAGAAACTATGCTGGCTGTGAAAAATATCACAATGCACCTGCTAAAGAAATGTCCCTGAGACA
GCCCAAGGCTCAGGTCAACTGCCATAGGATTCTGAGCAAGGCCTACTTGGCCCTGGATAGAAATTGTTTTCAAAGAGAAGGGCAGCTGCT
TAGAGTGAACATGTCTATGGACTTTAAAAAGACCCCACGCAATTTGACTTTGTGGCAATAGAAAACAGTAAAAAACAGGGCATAGCCTAG
TTTGTTATAAGAAAAAGCATCCATTTTCTATCCTTTTAGAGTCTTATTTGATTATGGTGGGAGGGAATGTTTTCAAATTTCCCATTTCTC
AAGAAATGTTCATATTAATTGAGGATTTCCCTTCAATAAATCTCATGTCCTCAATTA

>5850_5850_5_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000297770_length(amino acids)=737AA_BP=512
METSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMV
EWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPK
RGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKF
AARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPT
KSSKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAI
RIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNV
DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQML
LYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTE
TMLAVKNITMHLLKKCP

--------------------------------------------------------------
>5850_5850_6_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000518549_length(transcript)=2256nt_BP=1568nt
AGGTGTTCTTTAAAGAAATTTTCTTATACATTTTGGAAACTTCTACCAGCTCATTTGATCACAAATGGATGGTTATTCAGACACTGACGA
GGATTTGTGCAGATGCTCAGAGTGTAGTGGATATTTATGTAAACTATGACTGTGACTTAAATGCAGCCAATATATTTGAAAGACTAGTAA
ATGATCTATCAAAAATTGCTCAAGGAAGGGGCAGTCAAGAACTTGGTATGAGTAATGTTCAGGAATTGAGCCTGAGGAAAAAAGGTTTAG
AATGCTTAGTGTCGATTTTGAAGTGTATGGTTGAATGGAGTAAGGATCAGTATGTGAATCCCAACTCCCAGACAACTCTTGGTCAGGAAA
AACCCTCAGAGCAAGAGATGAGTGAAATCAAACACCCTGAGACAATAAACAGATACGGAAGTTTAAATTCCCTGGAGTCAACATCATCAT
CAGGAATAGGCAGCTACAGTACACAGATGTCTGGCACTGATAATCCAGAACAATTTGAGGTCCTAAAGCAACAAAAAGAAATAATAGAAC
AAGGGATAGATTTATTTAATAAGAAACCAAAGAGAGGAATACAGTACCTCCAAGAACAAGGGATGCTTGGCACCACACCTGAAGATATTG
CCCAATTCTTACATCAAGAGGAAAGATTAGACTCTACTCAAGTGGGTGAGTTCCTGGGAGATAATGATAAATTTAACAAAGAAGTCATGT
ATGCATATGTGGACCAACATGACTTTTCAGGAAAAGACTTCGTTTCAGCCCTTCGTATGTTTCTAGAAGGATTTCGTCTTCCAGGGGAAG
CTCAGAAAATCGATCGATTAATGGAAAAATTTGCTGCAAGATACCTAGAATGCAACCAAGGACAAACTCTCTTTGCTAGTGCGGATACAG
CTTATGTTTTGGCTTATTCAATTATCATGTTGACCACAGACCTTCACAGTCCACAGGTGAAAAATAAAATGACAAAGGAACAATACATTA
AGATGAATAGAGGTATCAATGACAGTAAAGACCTTCCTGAAGAGTATCTATCAGCCATCTATAATGAAATAGCTGGGAAAAAGATATCAA
TGAAAGAAACAAAAGAACTAACAATCCCTACAAAATCAAGTAAACAGAATGTAGCCAGTGAAAAACAAAGAAGACTTCTGTATAACTTAG
AAATGGAGCAGATGGCCAAGACAGCTAAAGCACTCATGGAGGCCGTGAGCCATGTTCAGGCACCCTTTACAAGTGCAACACATTTGGAGC
ATGTGAGGCCCATGTTTAAGTTGGCTTGGACGCCTTTTCTGGCTGCATTCAGTGTGGGTCTACAAGATTGTGATGATACTGAAGTAGCCT
CTCTTTGCCTGGAAGGTATAAGATGTGCAATCAGAATTGCATGCATTTTCAGCATTCAGCTGGAGAGAGATGCATATGTCCAGGCACTAG
CAAGATTTACCTTACTCACAGTGAGTTCCGGTATTACTGAAATGAAACAGAAGAACATTGACACAATAAAAACACTTATCACAGTGGCTC
ATACAGATGGAAATTATTTAGGAAATTCATGGCATGAGGCTCTTCTAACATATAAGAGTGACCCAGCCATGAGAAAAATGTTGAATCATC
TATATTTCTATATCATGCCTGTGTTTAACGTCGATGGATACCATTTTAGTTGGACCAATGATCGATTTTGGAGAAAAACAAGGTCAAGGA
ACTCAAGGTTTCGCTGCCGTGGAGTGGATGCCAATAGAAACTGGAAAGTGAAGTGGTGTGGTAAGTTTGGGACCAACTGGGATCCAGATC
CAAAGGTTTCTGCAGGTTTTACTCTGCAAAATATGAGTCCAGAGGACTCTCATGGGAGACTCATGTTTTTCTGTATGTGAAAACCTGGTA
GAGAAAGGTACAGATACGTACATGATAGCTGTAATTGGCAAAAGAAAATGAAAGGATTCTTTTTTAATATATAAAAATCAAGGATTTTAA
ATATGTCAATTCGGTCCTGAAAACTGAAAATTTAAATACATATGTAAAAGCAGCAAACTGAGGAATATTTGTCATTCCCCAAATTAAAAC
ATGAACCGTGGTGTAGTATAATTCTGGTTAAATCTTTTTATCCTTTTCATACAAGCACCACTGATGCTGCATTCGGCTGTCTGTCGTGGT
CAGAGCTGTCATGACCTTGTCTATATTCTACCACTCTGCTGGTCATACGTGGATTGACCATGCACATTGGGAATGTATTTCTGCTGCATT
CCATGT

>5850_5850_6_ARFGEF1-CPA6_ARFGEF1_chr8_68150970_ENST00000520381_CPA6_chr8_68397024_ENST00000518549_length(amino acids)=615AA_BP=512
METSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMV
EWSKDQYVNPNSQTTLGQEKPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPK
RGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKF
AARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPT
KSSKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAI
RIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEALLTYKSDPAMRKMLNHLYFYIMPVFNV
DGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKVKWCGKFGTNWDPDPKVSAGFTLQNMSPEDSHGRLMFFCM

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARFGEF1-CPA6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARFGEF1-CPA6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARFGEF1-CPA6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC3280730EPILEPSY, FAMILIAL TEMPORAL LOBE, 52CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC3280734FEBRILE SEIZURES, FAMILIAL, 112CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC4749273Benign familial mesial temporal lobe epilepsy1ORPHANET