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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ALDH1L1-SLC41A3 (FusionGDB2 ID:HG10840TG54946)

Fusion Gene Summary for ALDH1L1-SLC41A3

check button Fusion gene summary
Fusion gene informationFusion gene name: ALDH1L1-SLC41A3
Fusion gene ID: hg10840tg54946
HgeneTgene
Gene symbol

ALDH1L1

SLC41A3

Gene ID

10840

54946

Gene namealdehyde dehydrogenase 1 family member L1solute carrier family 41 member 3
Synonyms10-FTHFDH|10-fTHF|FDH|FTHFDSLC41A1-L2
Cytomap('ALDH1L1')('SLC41A3')

3q21.3

3q21.2-q21.3

Type of geneprotein-codingprotein-coding
Descriptioncytosolic 10-formyltetrahydrofolate dehydrogenase10-formyltetrahydrofolate dehydrogenaseMER57B-ALDH1L1solute carrier family 41 member 3SLC41A1-like 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000273450, ENST00000393431, 
ENST00000393434, ENST00000452905, 
ENST00000472186, ENST00000413612, 
ENST00000455064, 		ENST00000393431, 
ENST00000393434, ENST00000452905, 
ENST00000455064, ENST00000472186, 
ENST00000413612, ENST00000273450, 
Fusion gene scores* DoF score3 X 3 X 2=189 X 7 X 7=441
# samples 39
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/441*10)=-2.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ALDH1L1 [Title/Abstract] AND SLC41A3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointALDH1L1(125872287)-SLC41A3(125769893), # samples:2
Anticipated loss of major functional domain due to fusion event.ALDH1L1-SLC41A3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ALDH1L1-SLC41A3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ALDH1L1-SLC41A3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ALDH1L1-SLC41A3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ALDH1L1-SLC41A3 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SLC41A3-ALDH1L1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ALDH1L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SLC41A3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-DD-AADM-01AALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
ChimerDB4LIHCTCGA-DD-AADMALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-


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Fusion Gene ORF analysis for ALDH1L1-SLC41A3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000273450ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-5UTRENST00000393431ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-5UTRENST00000393434ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-5UTRENST00000452905ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-5UTRENST00000472186ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000273450ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000273450ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000273450ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000273450ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393431ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393431ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393431ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393431ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393434ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393434ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393434ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000393434ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000452905ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000452905ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000452905ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000452905ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000472186ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000472186ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000472186ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5CDS-intronENST00000472186ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-3CDSENST00000413612ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-5UTRENST00000413612ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-intronENST00000413612ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-intronENST00000413612ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-intronENST00000413612ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
5UTR-intronENST00000413612ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
Frame-shiftENST00000472186ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
In-frameENST00000273450ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
In-frameENST00000393431ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
In-frameENST00000393434ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
In-frameENST00000452905ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-3CDSENST00000455064ENST00000360370ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-5UTRENST00000455064ENST00000508835ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-intronENST00000455064ENST00000315891ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-intronENST00000455064ENST00000346785ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-intronENST00000455064ENST00000383598ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-
intron-intronENST00000455064ENST00000514023ALDH1L1chr3

125872287

-SLC41A3chr3

125769893

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000273450ALDH1L1chr3125872287-ENST00000360370SLC41A3chr3125769893-295811062182296692
ENST00000452905ALDH1L1chr3125872287-ENST00000360370SLC41A3chr3125769893-2541689141879621
ENST00000393434ALDH1L1chr3125872287-ENST00000360370SLC41A3chr3125769893-306012081432398751
ENST00000393431ALDH1L1chr3125872287-ENST00000360370SLC41A3chr3125769893-283398132171722

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000273450ENST00000360370ALDH1L1chr3125872287-SLC41A3chr3125769893-0.0051104670.9948895
ENST00000452905ENST00000360370ALDH1L1chr3125872287-SLC41A3chr3125769893-0.0053007260.99469924
ENST00000393434ENST00000360370ALDH1L1chr3125872287-SLC41A3chr3125769893-0.0037008930.9962991
ENST00000393431ENST00000360370ALDH1L1chr3125872287-SLC41A3chr3125769893-0.0043958980.99560416

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Fusion Genomic Features for ALDH1L1-SLC41A3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ALDH1L1-SLC41A3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:125872287/chr3:125769893)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-7231_203296913.0RegionNote=GART
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-72388_90296913.0RegionNote=Substrate binding
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-7231_203286903.0RegionNote=GART
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-72388_90286903.0RegionNote=Substrate binding
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-52188_90185802.0RegionNote=Substrate binding
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-7231_203286903.0RegionNote=GART
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-72388_90286903.0RegionNote=Substrate binding
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112378_38191508.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011378_3810472.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010378_38165462.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010378_3810371.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112152_17291508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112189_20991508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112220_24091508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112252_27291508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112284_30491508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112314_33491508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112377_39791508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112406_42691508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000315891112482_50291508.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011152_1720472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011189_2090472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011220_2400472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011252_2720472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011284_3040472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011314_3340472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011377_3970472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011406_4260472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000346785011482_5020472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST0000034678501167_870472.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010152_17265462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010189_20965462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010220_24065462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010252_27265462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010284_30465462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010314_33465462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010377_39765462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010406_42665462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000383598010482_50265462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST0000038359801067_8765462.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010152_1720371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010189_2090371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010220_2400371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010252_2720371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010284_3040371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010314_3340371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010377_3970371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010406_4260371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST00000508835010482_5020371.0TransmembraneHelical
TgeneSLC41A3chr3:125872287chr3:125769893ENST0000050883501067_870371.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723318_395296913.0DomainCarrier
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723318_395286903.0DomainCarrier
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521318_395185802.0DomainCarrier
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723318_395286903.0DomainCarrier
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723571_573296913.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723597_600296913.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723630_635296913.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723650_651296913.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723804_806296913.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723571_573286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723597_600286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723630_635286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723650_651286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723804_806286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521571_573185802.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521597_600185802.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521630_635185802.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521650_651185802.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521804_806185802.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723571_573286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723597_600286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723630_635286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723650_651286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723804_806286903.0Nucleotide bindingNADP
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000273450-723417_902296913.0RegionNote=Aldehyde dehydrogenase
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000393434-723417_902286903.0RegionNote=Aldehyde dehydrogenase
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-5211_203185802.0RegionNote=GART
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000452905-521417_902185802.0RegionNote=Aldehyde dehydrogenase
HgeneALDH1L1chr3:125872287chr3:125769893ENST00000472186-723417_902286903.0RegionNote=Aldehyde dehydrogenase
TgeneSLC41A3chr3:125872287chr3:125769893ENST0000031589111267_8791508.0TransmembraneHelical


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Fusion Gene Sequence for ALDH1L1-SLC41A3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3857_3857_1_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000273450_SLC41A3_chr3_125769893_ENST00000360370_length(transcript)=2958nt_BP=1106nt
TCTGCGGCACCAGGACTGAGTAGAAGGGAGAGAGTGGAGAAGGGGAATTGCAGAGAGAAAACCAGGGGCTGTTTTTCTCTCGGAGAGGCG
GGTAGGCACTGGGCGGGCAGAAGCGCCGCTATCCACCCGGATGCGCAGCTGCTAAGGGGCCGCCTCTGCAAGCGGCTGCAAATTCCCGGA
GGGCAGCGTCTCCTTTCGCTCTGCTGTGTCCGTAGCACATGGCAGGTCCTTCCAACCCTCCTGCTACCATGAAGATTGCAGTGATTGGAC
AGAGCCTGTTTGGCCAGGAAGTTTACTGCCACCTGAGGAAGGAGGGCCACGAAGTGGTGGGTGTGTTCACTGTTCCAGACAAGGATGGAA
AGGCCGACCCCCTGGGTCTGGAAGCTGAGAAGGATGGAGTGCCGGTATTCAAGTACTCCCGGTGGCGTGCAAAAGGACAGGCTTTGCCTG
ATGTGGTGGCAAAATACCAGGCTTTGGGGGCCGAGCTCAACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAGATAATCAGTGCCC
CCCGGCATGGCTCCATCATCTATCACCCGTCACTGCTCCCTAGGCACCGAGGGGCCTCGGCCATCAACTGGACCCTCATTCACGGAGATA
AGAAAGGGGGGTTTTCCATCTTCTGGGCGGATGATGGTCTGGACACCGGAGACCTGCTGCTGCAGAAGGAGTGTGAGGTGCTCCCGGACG
ACACCGTGAGCACGCTGTACAACCGCTTCCTCTTCCCTGAAGGCATCAAAGGGATGGTGCAGGCCGTGAGGCTGATCGCTGAGGGCAAAG
CCCCCAGACTCCCTCAGCCTGAGGAAGGAGCCACCTATGAGGGGATTCAGAAGAAGGAGACAGCCAAGATCAACTGGGACCAGCCGGCAG
AGGCCATTCACAACTGGATCCGCGGGAACGACAAGGTGCCGGGAGCCTGGACAGAGGCCTGTGAACAGAAACTGACATTTTTCAACTCAA
CGCTGAACACTTCAGGCCTGGTGCCCGAGGGAGACGCTTTGCCCATCCCAGGAGCCCATCGGCCAGGGGTGGTCACCAAAGCAGGACTCA
TCCTCTTTGGGAATGATGACAAAATGCACTGGCCTGTGTTTGTGGAGGTGAAAGACCTTTTGACATTGGTGCCGCCCCTGGTGGGCCTGA
AGGGGAACCTGGAGATGACACTGGCATCCAGACTCTCCACAGCTGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGCACAGAGTCA
TCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCGTGGTGTCTC
GAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGGGGGTGCTGA
TGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAGACCTCATCA
CACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCAGCTTTGCGG
CTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCATCCTGGCCA
TGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCCCCGTCATAT
GTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCCTGCCCCTCC
AGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCTTGCTGGTGG
TCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGCTCTACCTGC
TGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATCCTGACAACC
ACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGCTACTGAAGAGCA
AGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAGAATTTCCTCTCA
CATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTTTGTGAGTCTGCT
AAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGATACCTGAGCCTGCAATAGAGCCCTGAAATCAAGAGCATGGCTTGAGTGTGTGAAT
ATGATGTGTGCACATGCTTAATGAGCGTGCAAGTGTGCACACGTTTGTGGAGAGGAGGGTGTTCTGGCCTGAGAAGGTAAAGAAGAGGCA
TGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTTTCCATGCCCATGCAACCCAGATTGGGGTGGAGCAGGAAGGAGCTCTTTTCTGTTC
CCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTGCTGTCTTCACCAGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGCCAAGAAGGT
GTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATTTTCCTTTTT
GTTTGTTAGCAAAAACCTCTATTTAGATTTCAATAATCAGAGAAGTGTAAAATAAAACAGATTATATTGTACTTGACC

>3857_3857_1_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000273450_SLC41A3_chr3_125769893_ENST00000360370_length(amino acids)=692AA_BP=2
MAGPSNPPATMKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAEL
NVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFP
EGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDA
LPIPGAHRPGVVTKAGLILFGNDDKMHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQEQHRVISSNLALIQVQAT
VVGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKLGVNPDNIATPIAASLGDLITLSILALVSSFFY
RHKDSRYLTPLVCLSFAALTPVWVLIAKQSPPIVKILKFGWFPIILAMVISSFGGLILSKTVSKQQYKGMAIFTPVICGVGGNLVAIQTS
RISTYLHMWSAPGVLPLQMKKFWPNPCSTFCTSEINSMSARVLLLLVVPGHLIFFYIIYLVEGQSVINSQTFVVLYLLAGLIQVTILLYL
AEVMVRLTWHQALDPDNHCIPYLTGLGDLLGTGLLALCFFTDWLLKSKAELGGISELASGPP

--------------------------------------------------------------
>3857_3857_2_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000393431_SLC41A3_chr3_125769893_ENST00000360370_length(transcript)=2833nt_BP=981nt
CTCCTGGCTCCCAGGACGGGTCTGCACCAACCTCAGTTTCGGGGCTGCGGCTCACAGAAGTCTAACCTGCCCGGGACGCCCGCACCAACT
CCTGCGCGCGGTCCTTCCAACCCTCCTGCTACCATGAAGATTGCAGTGATTGGACAGAGCCTGTTTGGCCAGGAAGTTTACTGCCACCTG
AGGAAGGAGGGCCACGAAGTGGTGGGTGTGTTCACTGTTCCAGACAAGGATGGAAAGGCCGACCCCCTGGGTCTGGAAGCTGAGAAGGAT
GGAGTGCCGGTATTCAAGTACTCCCGGTGGCGTGCAAAAGGACAGGCTTTGCCTGATGTGGTGGCAAAATACCAGGCTTTGGGGGCCGAG
CTCAACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAGATAATCAGTGCCCCCCGGCATGGCTCCATCATCTATCACCCGTCACTG
CTCCCTAGGCACCGAGGGGCCTCGGCCATCAACTGGACCCTCATTCACGGAGATAAGAAAGGGGGGTTTTCCATCTTCTGGGCGGATGAT
GGTCTGGACACCGGAGACCTGCTGCTGCAGAAGGAGTGTGAGGTGCTCCCGGACGACACCGTGAGCACGCTGTACAACCGCTTCCTCTTC
CCTGAAGGCATCAAAGGGATGGTGCAGGCCGTGAGGCTGATCGCTGAGGGCAAAGCCCCCAGACTCCCTCAGCCTGAGGAAGGAGCCACC
TATGAGGGGATTCAGAAGAAGGAGACAGCCAAGATCAACTGGGACCAGCCGGCAGAGGCCATTCACAACTGGATCCGCGGGAACGACAAG
GTGCCGGGAGCCTGGACAGAGGCCTGTGAACAGAAACTGACATTTTTCAACTCAACGCTGAACACTTCAGGCCTGGTGCCCGAGGGAGAC
GCTTTGCCCATCCCAGGAGCCCATCGGCCAGGGGTGGTCACCAAAGCAGGACTCATCCTCTTTGGGAATGATGACAAAATGCACTGGCCT
GTGTTTGTGGAGGTGAAAGACCTTTTGACATTGGTGCCGCCCCTGGTGGGCCTGAAGGGGAACCTGGAGATGACACTGGCATCCAGACTC
TCCACAGCTGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGCACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCC
ACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCGTGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTG
TGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGGGGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGG
GTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAGACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTC
TACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCAGCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAG
AGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCATCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGC
AAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCCCCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACC
AGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCCTGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACT
TTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCTTGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTAC
CTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGCTCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTAC
CTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATCCTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTG
CTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGCTACTGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCT
GGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAGAATTTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGC
CAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTTTGTGAGTCTGCTAAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGA
TACCTGAGCCTGCAATAGAGCCCTGAAATCAAGAGCATGGCTTGAGTGTGTGAATATGATGTGTGCACATGCTTAATGAGCGTGCAAGTG
TGCACACGTTTGTGGAGAGGAGGGTGTTCTGGCCTGAGAAGGTAAAGAAGAGGCATGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTT
TCCATGCCCATGCAACCCAGATTGGGGTGGAGCAGGAAGGAGCTCTTTTCTGTTCCCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTG
CTGTCTTCACCAGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGCCAAGAAGGTGTACAGCCTCCCCAGGATGGGGCCTCATACAACCC
TTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATTTTCCTTTTTGTTTGTTAGCAAAAACCTCTATTTAGATTTCAATA
ATCAGAGAAGTGTAAAATAAAACAGATTATATTGTACTTGACC

>3857_3857_2_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000393431_SLC41A3_chr3_125769893_ENST00000360370_length(amino acids)=722AA_BP=1
MAPRTGLHQPQFRGCGSQKSNLPGTPAPTPARGPSNPPATMKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDG
VPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDG
LDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKV
PGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLS
TAANTGQIDDPQEQHRVISSNLALIQVQATVVGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKLGV
NPDNIATPIAASLGDLITLSILALVSSFFYRHKDSRYLTPLVCLSFAALTPVWVLIAKQSPPIVKILKFGWFPIILAMVISSFGGLILSK
TVSKQQYKGMAIFTPVICGVGGNLVAIQTSRISTYLHMWSAPGVLPLQMKKFWPNPCSTFCTSEINSMSARVLLLLVVPGHLIFFYIIYL
VEGQSVINSQTFVVLYLLAGLIQVTILLYLAEVMVRLTWHQALDPDNHCIPYLTGLGDLLGTGLLALCFFTDWLLKSKAELGGISELASG
PP

--------------------------------------------------------------
>3857_3857_3_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000393434_SLC41A3_chr3_125769893_ENST00000360370_length(transcript)=3060nt_BP=1208nt
ACAGTAAGTCTTCTTGACCTAAGCGGGAAAGAGCGCAGGCCCCTGCGGGGTTGGCTTTTACATGGCATTTATAGACCCGCCCGGAGAGGG
TGCGCTGCGCTCCCGCCATAGTCCCACCACCGGTGAGCGCCGCCCCCACTCGGCTGACTCTCCGCCCGCCCCGCGCCCCTCCCCTCACGG
GCTCTGGCCTTAACCAGAGCTCGCGGACTGGCGGGGACAGGTCCCACCTCCTGGCTCCCAGGACGGGTCTGCACCAACCTCAGTTTCGGG
GCTGCGGCTCACAGAAGTCTAACCTGCCCGGGACGCCCGCACCAACTCCTGCGCGCGGTCCTTCCAACCCTCCTGCTACCATGAAGATTG
CAGTGATTGGACAGAGCCTGTTTGGCCAGGAAGTTTACTGCCACCTGAGGAAGGAGGGCCACGAAGTGGTGGGTGTGTTCACTGTTCCAG
ACAAGGATGGAAAGGCCGACCCCCTGGGTCTGGAAGCTGAGAAGGATGGAGTGCCGGTATTCAAGTACTCCCGGTGGCGTGCAAAAGGAC
AGGCTTTGCCTGATGTGGTGGCAAAATACCAGGCTTTGGGGGCCGAGCTCAACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAGA
TAATCAGTGCCCCCCGGCATGGCTCCATCATCTATCACCCGTCACTGCTCCCTAGGCACCGAGGGGCCTCGGCCATCAACTGGACCCTCA
TTCACGGAGATAAGAAAGGGGGGTTTTCCATCTTCTGGGCGGATGATGGTCTGGACACCGGAGACCTGCTGCTGCAGAAGGAGTGTGAGG
TGCTCCCGGACGACACCGTGAGCACGCTGTACAACCGCTTCCTCTTCCCTGAAGGCATCAAAGGGATGGTGCAGGCCGTGAGGCTGATCG
CTGAGGGCAAAGCCCCCAGACTCCCTCAGCCTGAGGAAGGAGCCACCTATGAGGGGATTCAGAAGAAGGAGACAGCCAAGATCAACTGGG
ACCAGCCGGCAGAGGCCATTCACAACTGGATCCGCGGGAACGACAAGGTGCCGGGAGCCTGGACAGAGGCCTGTGAACAGAAACTGACAT
TTTTCAACTCAACGCTGAACACTTCAGGCCTGGTGCCCGAGGGAGACGCTTTGCCCATCCCAGGAGCCCATCGGCCAGGGGTGGTCACCA
AAGCAGGACTCATCCTCTTTGGGAATGATGACAAAATGCACTGGCCTGTGTTTGTGGAGGTGAAAGACCTTTTGACATTGGTGCCGCCCC
TGGTGGGCCTGAAGGGGAACCTGGAGATGACACTGGCATCCAGACTCTCCACAGCTGCCAACACTGGACAAATTGATGACCCCCAGGAGC
AGCACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGG
GCGTGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCC
TGGGGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGG
GAGACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCC
TCAGCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAA
TCATCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTA
CCCCCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCG
TCCTGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGC
TCTTGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGG
TGCTCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGG
ATCCTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGC
TACTGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAG
AATTTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTT
TGTGAGTCTGCTAAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGATACCTGAGCCTGCAATAGAGCCCTGAAATCAAGAGCATGGCTT
GAGTGTGTGAATATGATGTGTGCACATGCTTAATGAGCGTGCAAGTGTGCACACGTTTGTGGAGAGGAGGGTGTTCTGGCCTGAGAAGGT
AAAGAAGAGGCATGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTTTCCATGCCCATGCAACCCAGATTGGGGTGGAGCAGGAAGGAGC
TCTTTTCTGTTCCCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTGCTGTCTTCACCAGGTTCAAGCTCCGTGGGCCACACTGCTGCTG
TGCCAAGAAGGTGTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTT
ATTTTCCTTTTTGTTTGTTAGCAAAAACCTCTATTTAGATTTCAATAATCAGAGAAGTGTAAAATAAAACAGATTATATTGTACTTGACC


>3857_3857_3_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000393434_SLC41A3_chr3_125769893_ENST00000360370_length(amino acids)=751AA_BP=1
MTLRPPRAPPLTGSGLNQSSRTGGDRSHLLAPRTGLHQPQFRGCGSQKSNLPGTPAPTPARGPSNPPATMKIAVIGQSLFGQEVYCHLRK
EGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLP
RHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYE
GIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMHWPVF
VEVKDLLTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDPQEQHRVISSNLALIQVQATVVGLLAAVAALLLGVVSREEVDVAKVELLCA
SSVLTAFLAAFALGVLMVCIVIGARKLGVNPDNIATPIAASLGDLITLSILALVSSFFYRHKDSRYLTPLVCLSFAALTPVWVLIAKQSP
PIVKILKFGWFPIILAMVISSFGGLILSKTVSKQQYKGMAIFTPVICGVGGNLVAIQTSRISTYLHMWSAPGVLPLQMKKFWPNPCSTFC
TSEINSMSARVLLLLVVPGHLIFFYIIYLVEGQSVINSQTFVVLYLLAGLIQVTILLYLAEVMVRLTWHQALDPDNHCIPYLTGLGDLLG
TGLLALCFFTDWLLKSKAELGGISELASGPP

--------------------------------------------------------------
>3857_3857_4_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000452905_SLC41A3_chr3_125769893_ENST00000360370_length(transcript)=2541nt_BP=689nt
ACAGGTCCCACCTCCTGGCTCCCAGGACGGGTCTGCACCAACCTCAGTTTCGGGGCTGCGGCTCACAGAAGTCTAACCTGCCCGGGACGC
CCGCACCAACTCCTGCGCGCGGTCCTTCCAACCCTCCTGCTACCATGAAGATTGCAGTGATTGGACAGAGCCTGTTTGGCCAGGAAGTTT
ACTGCCACCTGAGGAAGGAGGGCCACGAAGTGGTGGGTGTGTTCACTGTTCCAGACAAGGATGGAAAGGCCGACCCCCTGGGTCTGGAAG
CTGAGAAGGATGGAGTGCCGGTATTCAAGTACTCCCGGTGGCGTGCAAAAGGACAGGCTTTGCCTGATGTGGTGGCAAAATACCAGGCTT
TGGGGGCCGAGCTCAACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAGATAATCAGTGCCCCCCGGCATGGCTCCATCATCTATC
ACCCGTCACTGCTCCCTAGGCACCGAGGGGCCTCGGCCATTCACAACTGGATCCGCGGGAACGACAAGGTGCCGGGAGCCTGGACAGAGG
CCTGTGAACAGAAACTGACATTTTTCAACTCAACGCTGAACACTTCAGGCCTGGTGCCCGAGGGAGACGCTTTGCCCATCCCAGGAGCCC
ATCGGCCAGGGGTGGTCACCAAAGCAGGACTCATCCTCTTTGGGAATGATGACAAAATGCACTGGCCTGTGTTTGTGGAGGTGAAAGACC
TTTTGACATTGGTGCCGCCCCTGGTGGGCCTGAAGGGGAACCTGGAGATGACACTGGCATCCAGACTCTCCACAGCTGCCAACACTGGAC
AAATTGATGACCCCCAGGAGCAGCACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTG
CTGTGGCTGCGCTGCTGTTGGGCGTGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTG
CCTTCCTTGCAGCCTTTGCCCTGGGGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCA
CGCCCATTGCAGCCAGCCTGGGAGACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGT
ATCTGACGCCGCTGGTCTGCCTCAGCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCC
TGAAGTTTGGCTGGTTCCCAATCATCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGT
ACAAAGGCATGGCGATATTTACCCCCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGC
ACATGTGGAGTGCACCTGGCGTCCTGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATT
CCATGTCAGCTCGAGTCCTGCTCTTGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCA
TAAACAGCCAGACCTTTGTGGTGCTCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGC
TGACTTGGCACCAGGCCCTGGATCCTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCAC
TCTGCTTTTTCACTGACTGGCTACTGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCG
CTGGTCCCATTTGCTCATTAGAATTTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACC
CCTGCCTCTGCAGTAGCCTTTTGTGAGTCTGCTAAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGATACCTGAGCCTGCAATAGAGCC
CTGAAATCAAGAGCATGGCTTGAGTGTGTGAATATGATGTGTGCACATGCTTAATGAGCGTGCAAGTGTGCACACGTTTGTGGAGAGGAG
GGTGTTCTGGCCTGAGAAGGTAAAGAAGAGGCATGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTTTCCATGCCCATGCAACCCAGAT
TGGGGTGGAGCAGGAAGGAGCTCTTTTCTGTTCCCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTGCTGTCTTCACCAGGTTCAAGCT
CCGTGGGCCACACTGCTGCTGTGCCAAGAAGGTGTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAA
TCGTGTCCTTGCTGTCTTTTTATTTTCCTTTTTGTTTGTTAGCAAAAACCTCTATTTAGATTTCAATAATCAGAGAAGTGTAAAATAAAA
CAGATTATATTGTACTTGACC

>3857_3857_4_ALDH1L1-SLC41A3_ALDH1L1_chr3_125872287_ENST00000452905_SLC41A3_chr3_125769893_ENST00000360370_length(amino acids)=621AA_BP=1
MAPRTGLHQPQFRGCGSQKSNLPGTPAPTPARGPSNPPATMKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDG
VPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAIHNWIRGNDKVPGAWTEACEQK
LTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMHWPVFVEVKDLLTLVPPLVGLKGNLEMTLASRLSTAANTGQIDDP
QEQHRVISSNLALIQVQATVVGLLAAVAALLLGVVSREEVDVAKVELLCASSVLTAFLAAFALGVLMVCIVIGARKLGVNPDNIATPIAA
SLGDLITLSILALVSSFFYRHKDSRYLTPLVCLSFAALTPVWVLIAKQSPPIVKILKFGWFPIILAMVISSFGGLILSKTVSKQQYKGMA
IFTPVICGVGGNLVAIQTSRISTYLHMWSAPGVLPLQMKKFWPNPCSTFCTSEINSMSARVLLLLVVPGHLIFFYIIYLVEGQSVINSQT
FVVLYLLAGLIQVTILLYLAEVMVRLTWHQALDPDNHCIPYLTGLGDLLGTGLLALCFFTDWLLKSKAELGGISELASGPP

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Fusion Gene PPI Analysis for ALDH1L1-SLC41A3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ALDH1L1-SLC41A3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ALDH1L1-SLC41A3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneALDH1L1C0003129Anoxemia1CTD_human
HgeneALDH1L1C0003130Anoxia1CTD_human
HgeneALDH1L1C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneALDH1L1C0028754Obesity1CTD_human
HgeneALDH1L1C0242184Hypoxia1CTD_human
HgeneALDH1L1C0700292Hypoxemia1CTD_human