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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ADAP1-MAD1L1 (FusionGDB2 ID:HG11033TG8379)

Fusion Gene Summary for ADAP1-MAD1L1

check button Fusion gene summary
Fusion gene informationFusion gene name: ADAP1-MAD1L1
Fusion gene ID: hg11033tg8379
HgeneTgene
Gene symbol

ADAP1

MAD1L1

Gene ID

11033

8379

Gene nameArfGAP with dual PH domains 1mitotic arrest deficient 1 like 1
SynonymsCENTA1|GCS1L|p42IP4MAD1|PIG9|TP53I9|TXBP181
Cytomap('ADAP1')('MAD1L1')

7p22.3

7p22.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with dual PH domain-containing protein 1centaurin-alphacentaurin-alpha-1cnt-a1putative MAPK-activating protein PM25mitotic spindle assembly checkpoint protein MAD1MAD1 mitotic arrest deficient like 1MAD1-like protein 1mitotic arrest deficient 1-like protein 1mitotic checkpoint MAD1 protein homologmitotic-arrest deficient 1, yeast, homolog-like 1tax-binding prote
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265846, ENST00000449296, 
ENST00000539900, ENST00000463358, 
Fusion gene scores* DoF score13 X 10 X 8=104023 X 16 X 12=4416
# samples 1837
** MAII scorelog2(18/1040*10)=-2.53051471669878
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(37/4416*10)=-3.57714299626186
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ADAP1 [Title/Abstract] AND MAD1L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointADAP1(966189)-MAD1L1(2108973), # samples:2
Anticipated loss of major functional domain due to fusion event.ADAP1-MAD1L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAP1-MAD1L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAP1-MAD1L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAP1-MAD1L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMAD1L1

GO:0007094

mitotic spindle assembly checkpoint

18981471

TgeneMAD1L1

GO:0090235

regulation of metaphase plate congression

20133940


check buttonFusion gene breakpoints across ADAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MAD1L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-DK-AA6P-01AADAP1chr7

966189

-MAD1L1chr7

2108973

-


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Fusion Gene ORF analysis for ADAP1-MAD1L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265846ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5CDS-intronENST00000449296ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5CDS-intronENST00000539900ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-3CDSENST00000463358ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
5UTR-intronENST00000463358ENST00000486340ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000265846ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000449296ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000265854ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000399654ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000402746ADAP1chr7

966189

-MAD1L1chr7

2108973

-
In-frameENST00000539900ENST00000406869ADAP1chr7

966189

-MAD1L1chr7

2108973

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265846ADAP1chr7966189-ENST00000402746MAD1L1chr72108973-18855252201608462
ENST00000265846ADAP1chr7966189-ENST00000399654MAD1L1chr72108973-18855252201608462
ENST00000265846ADAP1chr7966189-ENST00000406869MAD1L1chr72108973-18855252201608462
ENST00000265846ADAP1chr7966189-ENST00000265854MAD1L1chr72108973-18685252201608462
ENST00000449296ADAP1chr7966189-ENST00000402746MAD1L1chr72108973-1613253171336439
ENST00000449296ADAP1chr7966189-ENST00000399654MAD1L1chr72108973-1613253171336439
ENST00000449296ADAP1chr7966189-ENST00000406869MAD1L1chr72108973-1613253171336439
ENST00000449296ADAP1chr7966189-ENST00000265854MAD1L1chr72108973-1596253171336439
ENST00000539900ADAP1chr7966189-ENST00000402746MAD1L1chr72108973-169833801421473
ENST00000539900ADAP1chr7966189-ENST00000399654MAD1L1chr72108973-169833801421473
ENST00000539900ADAP1chr7966189-ENST00000406869MAD1L1chr72108973-169833801421473
ENST00000539900ADAP1chr7966189-ENST00000265854MAD1L1chr72108973-168133801421473

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265846ENST00000402746ADAP1chr7966189-MAD1L1chr72108973-0.0083633480.9916366
ENST00000265846ENST00000399654ADAP1chr7966189-MAD1L1chr72108973-0.0083633480.9916366
ENST00000265846ENST00000406869ADAP1chr7966189-MAD1L1chr72108973-0.0083633480.9916366
ENST00000265846ENST00000265854ADAP1chr7966189-MAD1L1chr72108973-0.0079452340.9920548
ENST00000449296ENST00000402746ADAP1chr7966189-MAD1L1chr72108973-0.0075805630.9924194
ENST00000449296ENST00000399654ADAP1chr7966189-MAD1L1chr72108973-0.0075805630.9924194
ENST00000449296ENST00000406869ADAP1chr7966189-MAD1L1chr72108973-0.0075805630.9924194
ENST00000449296ENST00000265854ADAP1chr7966189-MAD1L1chr72108973-0.0071577140.9928423
ENST00000539900ENST00000402746ADAP1chr7966189-MAD1L1chr72108973-0.0110068470.9889931
ENST00000539900ENST00000399654ADAP1chr7966189-MAD1L1chr72108973-0.0110068470.9889931
ENST00000539900ENST00000406869ADAP1chr7966189-MAD1L1chr72108973-0.0110068470.9889931
ENST00000539900ENST00000265854ADAP1chr7966189-MAD1L1chr72108973-0.0106176760.9893824

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Fusion Genomic Features for ADAP1-MAD1L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ADAP1-MAD1L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:966189/chr7:2108973)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-31121_44101375.0Zinc fingerC4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-311129_230101375.0DomainPH 1
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-311252_356101375.0DomainPH 2
HgeneADAP1chr7:966189chr7:2108973ENST00000265846-3117_126101375.0DomainArf-GAP
TgeneMAD1L1chr7:966189chr7:2108973ENST0000026585491846_632357719.0Coiled coilOntology_term=ECO:0000255
TgeneMAD1L1chr7:966189chr7:2108973ENST00000399654101946_632357719.0Coiled coilOntology_term=ECO:0000255
TgeneMAD1L1chr7:966189chr7:2108973ENST00000406869101946_632357719.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for ADAP1-MAD1L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2152_2152_1_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000265854_length(transcript)=1868nt_BP=525nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC
CCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAA

>2152_2152_1_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000265854_length(amino acids)=462AA_BP=100
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS
LTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_2_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000399654_length(transcript)=1885nt_BP=525nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC
CCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_2_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000399654_length(amino acids)=462AA_BP=100
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS
LTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_3_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000402746_length(transcript)=1885nt_BP=525nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC
CCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_3_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000402746_length(amino acids)=462AA_BP=100
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS
LTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_4_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000406869_length(transcript)=1885nt_BP=525nt
CCGGGCCCCGCGCCGGCACTCGCTCAGCGACCGCGGCGGAGACACGAGCGGCGGCGGCGGAGCCCAGAGGGCGGCGGGAATGCGGAACCG
GCGCGCGGGCTGAGGCCGCCCGGGATGGCGCAGGGGCGGCGGCGGCGGGCGGCCTGCGCGGGGCCCTAGCGAGCCGGGCTGACGCTCCCG
GCCCCGGCCCCGGCATCGGCATCGCGGGCGCATCGCGGCCATGGCCAAGGAGCGGCGCAGGGCGGTCCTGGAGCTGCTGCAGCGGCCGGG
GAACGCGCGCTGCGCGGACTGCGGCGCCCCGGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAAT
CCACCGGAATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGG
GAACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGA
GAAGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCT
GGCCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGAC
CCCGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGA
GGCTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCA
GTCCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAG
TCGGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCT
GCACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGG
GCTCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGA
GCTGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTG
CTACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCT
CATCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCA
CCTGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTC
GGGGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAG
CCCCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGAC
CCCATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_4_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000265846_MAD1L1_chr7_2108973_ENST00000406869_length(amino acids)=462AA_BP=100
MAKERRRAVLELLQRPGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGNDAARARFESKVP
SFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMR
EAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQL
ERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQ
RLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSS
LTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_5_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000265854_length(transcript)=1596nt_BP=253nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC
CATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAA

>2152_2152_5_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000265854_length(amino acids)=439AA_BP=77
MFRKHVLGPCSVSLQSPLRDSVLATSGSLAHQPISRPPCLAPVGSLLNFMASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQL
QEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQA
LEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNP
TSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGY
QIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_6_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000399654_length(transcript)=1613nt_BP=253nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC
CATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_6_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000399654_length(amino acids)=439AA_BP=77
MFRKHVLGPCSVSLQSPLRDSVLATSGSLAHQPISRPPCLAPVGSLLNFMASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQL
QEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQA
LEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNP
TSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGY
QIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_7_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000402746_length(transcript)=1613nt_BP=253nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC
CATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_7_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000402746_length(amino acids)=439AA_BP=77
MFRKHVLGPCSVSLQSPLRDSVLATSGSLAHQPISRPPCLAPVGSLLNFMASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQL
QEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQA
LEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNP
TSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGY
QIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_8_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000406869_length(transcript)=1613nt_BP=253nt
TTTCCTTCTCCCTCAGCCTGTTTCGTAAACATGTTCTGGGTCCCTGCAGTGTGTCCCTGCAGAGTCCCCTCAGAGACTCTGTCCTAGCCA
CATCTGGGTCTCTCGCTCACCAGCCCATCTCCAGGCCCCCGTGTCTGGCGCCTGTTGGCTCTTTGCTAAATTTCATGGCCTCCCACGGGA
ACGACGCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGA
AGGCCAGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGG
CCCGGAGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCC
CGGCCGAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGG
CTCAGCTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGT
CCAGCTCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTC
GGCTGGAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGC
ACATGAGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGC
TCCTGCGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGC
TGAAGAAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCT
ACACGCTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCA
TCTTCAAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACC
TGCGGCGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGG
GGGCATAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCC
CCACAGGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCC
CATGCGTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_8_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000449296_MAD1L1_chr7_2108973_ENST00000406869_length(amino acids)=439AA_BP=77
MFRKHVLGPCSVSLQSPLRDSVLATSGSLAHQPISRPPCLAPVGSLLNFMASHGNDAARARFESKVPSFYYRPTPSDCHARGLEKARQQL
QEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQA
LEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNP
TSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGY
QIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_9_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000265854_length(transcript)=1681nt_BP=338nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC
GTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAA

>2152_2152_9_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000265854_length(amino acids)=473AA_BP=111
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR
RQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_10_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000399654_length(transcript)=1698nt_BP=338nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC
GTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_10_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000399654_length(amino acids)=473AA_BP=111
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR
RQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_11_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000402746_length(transcript)=1698nt_BP=338nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC
GTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_11_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000402746_length(amino acids)=473AA_BP=111
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR
RQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------
>2152_2152_12_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000406869_length(transcript)=1698nt_BP=338nt
ATGTTCCAGTTTGTTTTCAGCCGGGTGTACTGCATTAACCCTGCAAGAAGAAAATGGAAAGAATTTGAAAAGATGCTGGGGTGTGCAGAG
GAAGGGCACGCGAGTCTGGGAAGAGATCCCGACTGGGCCTCCTACACTCTGGGCGTCTTCATCTGCCTGAGCTGCTCGGGAATCCACCGG
AATATCCCCCAGGTCAGCAAGGTGAAGTCCGTCCGCCTGGACGCCTGGGAGGAGGCCCAAGTGGAGTTCATGGCCTCCCACGGGAACGAC
GCCGCGAGAGCCAGGTTTGAGTCCAAAGTACCCTCCTTCTACTACCGGCCCACGCCCTCCGACTGCCACGCCCGGGGGCTGGAGAAGGCC
AGGCAGCAGCTGCAGGAGGAGCTCCGGCAGGTCAGCGGCCAGCTGTTGGAGGAGAGGAAGAAGCGCGAGACCCACGAGGCGCTGGCCCGG
AGGCTCCAGAAACGGGTCCTGCTGCTCACCAAGGAGCGGGACGGTATGCGGGCCATCCTGGGGTCCTACGACAGCGAGCTGACCCCGGCC
GAGTACTCACCCCAGCTGACGCGGCGCATGCGGGAGGCTGAGGATATGGTGCAGAAGGTGCACAGCCACAGCGCCGAGATGGAGGCTCAG
CTGTCGCAGGCCCTGGAGGAGCTGGGAGGCCAGAAACAAAGAGCAGACATGCTGGAGATGGAGCTGAAGATGCTGAAGTCTCAGTCCAGC
TCTGCCGAACAGAGCTTCCTGTTCTCCAGGGAGGAGGCGGACACGCTCAGGTTGAAGGTCGAGGAGCTGGAAGGCGAGCGGAGTCGGCTG
GAGGAGGAAAAGAGGATGCTGGAGGCACAGCTGGAGCGGCGAGCTCTGCAGGGTGACTATGACCAGAGCAGGACCAAAGTGCTGCACATG
AGCCTGAACCCCACCAGTGTGGCCAGGCAGCGCCTGCGCGAGGACCACAGCCAGCTGCAGGCGGAGTGCGAGCGACTGCGCGGGCTCCTG
CGCGCCATGGAGAGAGGAGGCACCGTCCCAGCCGACCTTGAGGCTGCCGCCGCGAGTCTGCCATCGTCCAAGGAGGTGGCAGAGCTGAAG
AAGCAGGTGGAGAGTGCCGAGCTGAAGAACCAGCGGCTCAAGGAGGTTTTCCAGACCAAGATCCAGGAGTTCCGCAAGGCCTGCTACACG
CTCACCGGCTACCAGATCGACATCACCACGGAGAACCAGTACCGGCTGACCTCGCTGTACGCCGAGCACCCAGGCGACTGCCTCATCTTC
AAGGCCACCAGCCCCTCGGGTTCCAAGATGCAGCTACTGGAGACAGAGTTCTCACACACCGTGGGCGAGCTCATCGAGGTGCACCTGCGG
CGCCAGGACAGCATCCCTGCCTTCCTCAGCTCGCTCACCCTCGAGCTCTTCAGCCGCCAGACCGTGGCGTAGCCTGCAGGCTCGGGGGCA
TAGCCGGAGCCACTCTGCTTGGCCTGACCTGCAGGTCCCCTGCCCCGCCAGCCACAGGCTGGGTGCACGTCCTGCCTCTCCAGCCCCACA
GGGCAGCAGCATGACTGACAGACACGCTGGGACCTACGTCGGGCTTCCTGCTGGGGCGGCCAGCACCCTCTCCACGTGCAGACCCCATGC
GTCCCGGAGCCTGGTGTGTGGGCGTCGGCCACCAGCCTGGGTTCCTCACCTTGTGAAATAAAATCTTCTCCCCTAGAC

>2152_2152_12_ADAP1-MAD1L1_ADAP1_chr7_966189_ENST00000539900_MAD1L1_chr7_2108973_ENST00000406869_length(amino acids)=473AA_BP=111
MFQFVFSRVYCINPARRKWKEFEKMLGCAEEGHASLGRDPDWASYTLGVFICLSCSGIHRNIPQVSKVKSVRLDAWEEAQVEFMASHGND
AARARFESKVPSFYYRPTPSDCHARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPA
EYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRL
EEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELK
KQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLR
RQDSIPAFLSSLTLELFSRQTVA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ADAP1-MAD1L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ADAP1-MAD1L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ADAP1-MAD1L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0087031Juvenile-Onset Still Disease1CTD_human
TgeneC1336708Testicular Germ Cell Tumor1CTD_human
TgeneC2931456Prostate cancer, familial1CTD_human
TgeneC3495559Juvenile arthritis1CTD_human
TgeneC3714758Juvenile psoriatic arthritis1CTD_human
TgeneC4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
TgeneC4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human
TgeneC4722327PROSTATE CANCER, HEREDITARY, 11CTD_human