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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABHD2-ACAN (FusionGDB2 ID:HG11057TG176)

Fusion Gene Summary for ABHD2-ACAN

check button Fusion gene summary
Fusion gene informationFusion gene name: ABHD2-ACAN
Fusion gene ID: hg11057tg176
HgeneTgene
Gene symbol

ABHD2

ACAN

Gene ID

11057

176

Gene nameabhydrolase domain containing 2, acylglycerol lipaseaggrecan
SynonymsHS1-2|LABH2|PHPS1-2AGC1|AGCAN|CSPG1|CSPGCP|MSK16|SEDK|SSOAOD
Cytomap('ABHD2')('ACAN')

15q26.1

15q26.1

Type of geneprotein-codingprotein-coding
Descriptionmonoacylglycerol lipase ABHD22-arachidonoylglycerol hydrolaseabhydrolase domain containing 2abhydrolase domain-containing protein 2acetylesterasealpha/beta hydrolase domain containing protein 2lung alpha/beta hydrolase 2progesterone-sensitive lipasaggrecan core proteincartilage-specific proteoglycan core proteinchondroitin sulfate proteoglycan core protein 1large aggregating proteoglycan
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000352732, ENST00000355100, 
ENST00000565973, ENST00000562254, 
Fusion gene scores* DoF score10 X 10 X 5=5005 X 5 X 3=75
# samples 115
** MAII scorelog2(11/500*10)=-2.18442457113743
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABHD2 [Title/Abstract] AND ACAN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABHD2(89698765)-ACAN(89398083), # samples:3
Anticipated loss of major functional domain due to fusion event.ABHD2-ACAN seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABHD2-ACAN seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABHD2

GO:0032570

response to progesterone

26989199

HgeneABHD2

GO:0043401

steroid hormone mediated signaling pathway

26989199

HgeneABHD2

GO:0046464

acylglycerol catabolic process

26989199

HgeneABHD2

GO:0048240

sperm capacitation

26989199


check buttonFusion gene breakpoints across ABHD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ACAN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A8OQ-01AABHD2chr15

89698765

-ACANchr15

89398083

+
ChimerDB4BRCATCGA-AC-A8OQ-01AABHD2chr15

89698765

+ACANchr15

89398083

+


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Fusion Gene ORF analysis for ABHD2-ACAN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000352732ENST00000352105ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000352732ENST00000558207ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000352732ENST00000559004ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000352732ENST00000561243ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000355100ENST00000352105ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000355100ENST00000558207ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000355100ENST00000559004ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000355100ENST00000561243ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000565973ENST00000352105ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000565973ENST00000558207ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000565973ENST00000559004ABHD2chr15

89698765

+ACANchr15

89398083

+
5CDS-intronENST00000565973ENST00000561243ABHD2chr15

89698765

+ACANchr15

89398083

+
In-frameENST00000352732ENST00000439576ABHD2chr15

89698765

+ACANchr15

89398083

+
In-frameENST00000355100ENST00000439576ABHD2chr15

89698765

+ACANchr15

89398083

+
In-frameENST00000565973ENST00000439576ABHD2chr15

89698765

+ACANchr15

89398083

+
intron-3CDSENST00000562254ENST00000439576ABHD2chr15

89698765

+ACANchr15

89398083

+
intron-intronENST00000562254ENST00000352105ABHD2chr15

89698765

+ACANchr15

89398083

+
intron-intronENST00000562254ENST00000558207ABHD2chr15

89698765

+ACANchr15

89398083

+
intron-intronENST00000562254ENST00000559004ABHD2chr15

89698765

+ACANchr15

89398083

+
intron-intronENST00000562254ENST00000561243ABHD2chr15

89698765

+ACANchr15

89398083

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000352732ABHD2chr1589698765+ENST00000439576ACANchr1589398083+7258105851163841957
ENST00000565973ABHD2chr1589698765+ENST00000439576ACANchr1589398083+7479127973266051957
ENST00000355100ABHD2chr1589698765+ENST00000439576ACANchr1589398083+7211101146463371957

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000352732ENST00000439576ABHD2chr1589698765+ACANchr1589398083+0.0030834830.99691653
ENST00000565973ENST00000439576ABHD2chr1589698765+ACANchr1589398083+0.0035846980.99641526
ENST00000355100ENST00000439576ABHD2chr1589698765+ACANchr1589398083+0.0026780610.9973219

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Fusion Genomic Features for ABHD2-ACAN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABHD2chr1589698765+ACANchr1589398082+2.64E-060.9999974
ABHD2chr1589698765+ACANchr1589398082+2.64E-060.9999974

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABHD2-ACAN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:89698765/chr15:89398083)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABHD2chr15:89698765chr15:89398083ENST00000352732+5111_9179426.0Topological domainCytoplasmic
HgeneABHD2chr15:89698765chr15:89398083ENST00000355100+7131_9179426.0Topological domainCytoplasmic
HgeneABHD2chr15:89698765chr15:89398083ENST00000565973+9151_9179426.0Topological domainCytoplasmic
HgeneABHD2chr15:89698765chr15:89398083ENST00000352732+51110_30179426.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneABHD2chr15:89698765chr15:89398083ENST00000355100+71310_30179426.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneABHD2chr15:89698765chr15:89398083ENST00000565973+91510_30179426.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABHD2chr15:89698765chr15:89398083ENST00000352732+511128_382179426.0DomainAB hydrolase-1
HgeneABHD2chr15:89698765chr15:89398083ENST00000355100+713128_382179426.0DomainAB hydrolase-1
HgeneABHD2chr15:89698765chr15:89398083ENST00000565973+915128_382179426.0DomainAB hydrolase-1
HgeneABHD2chr15:89698765chr15:89398083ENST00000352732+51131_425179426.0Topological domainExtracellular
HgeneABHD2chr15:89698765chr15:89398083ENST00000355100+71331_425179426.0Topological domainExtracellular
HgeneABHD2chr15:89698765chr15:89398083ENST00000565973+91531_425179426.0Topological domainExtracellular


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Fusion Gene Sequence for ABHD2-ACAN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>417_417_1_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000352732_ACAN_chr15_89398083_ENST00000439576_length(transcript)=7258nt_BP=1058nt
AGCCCTCCTCCCCTTTCCCCGCCCACTCCGGGCTGGCCTTATCCAGTAGCGTCTGGGTCCCTGGACTAAAGCCGTCAAATGTAACCAATT
GCTGAGGAGCTCTCCCCTAAGAATCCCGCCTCCACTCTGAGGAACAGCTTCGCTGATCAATGGATCCCCTCCTAGACGCAATGAGCGCGC
GGGGCAAGTGGAGAAGCGGCTGAACTGCCCAATGAACAAGCGGTTTCCGTGGTTAGGGGCGTGGCAGAAGCGGTCGTCAGGGGCGTGGCG
GCAGTTACTTGGGCGGGGCCGGTAGCGGCGGGAGCTGCACTGGCCAGGGGTTCCGGCTGTATATCCATGAGCGCCGCTGGCAGCCGGGGA
GCTGCAGGAACCAGACTGGGGGCGAGCTGAGCACCTGTAGTCAATCACACGCAGCTTTTAGGTTTGTTTGAATAAGAGATCTGACCTGAC
CGGCCCAACTGTACAACTCTTCAAGGAAAATTCGTATTTGCAGTGGGAAGAATAAGTAACATTGATCAAGATGAATGCCATGCTGGAGAC
TCCCGAACTCCCAGCCGTGTTTGATGGAGTGAAGCTGGCTGCAGTGGCTGCTGTGCTGTACGTGATCGTCCGGTGTTTGAACCTGAAGAG
CCCCACAGCCCCACCTGACCTCTACTTCCAGGACTCGGGGCTCTCACGCTTTCTGCTCAAGTCCTGTCCTCTTCTGACCAAAGAATACAT
TCCACCGTTGATCTGGGGGAAAAGTGGACACATCCAGACAGCCTTGTATGGGAAGATGGGAAGGGTGAGGTCGCCACATCCTTATGGGCA
CCGGAAGTTCATCACTATGTCTGATGGAGCCACTTCTACATTCGACCTCTTCGAGCCCTTGGCTGAGCACTGTGTTGGAGATGATATCAC
CATGGTCATCTGCCCTGGAATTGCCAATCACAGCGAGAAGCAATACATCCGCACTTTCGTTGACTACGCCCAGAAAAATGGCTATCGGTG
CGCCGTGCTGAACCACCTGGGTGCCCTGCCCAACATTGAATTGACCTCGCCACGCATGTTCACCTATGGGATCCTTCCTACTTGGCCTCC
CACTGGCGCAGCAACAGAGGAAAGTACAGAAGGCCCTTCTGCAACTGAAGTGCCCTCTGCCTCAGAGGAACCATCCCCCTCAGAGGTGCC
ATTCCCCTCAGAGGAGCCATCCCCCTCAGAGGAACCATTCCCCTCAGTGAGGCCATTCCCCTCAGTGGAGCTGTTCCCCTCAGAGGAGCC
ATTCCCCTCCAAGGAGCCATCCCCCTCAGAGGAACCATCAGCCTCGGAAGAGCCGTATACACCTTCACCCCCCGTGCCCAGCTGGACTGA
GCTGCCCAGCTCTGGGGAGGAATCTGGGGCCCCTGATGTCAGTGGTGACTTCACAGGCAGTGGAGATGTTTCAGGACACCTTGACTTCAG
TGGGCAGCTGTCAGGGGACAGGGCAAGTGGACTGCCCTCTGGAGACCTGGACTCCAGTGGTCTTACTTCCACAGTGGGCTCAGGCCTGCC
TGTGGAAAGTGGACTACCCTCAGGGGATGAAGAGAGAATTGAGTGGCCCAGCACTCCTACGGTTGGTGAACTGCCCTCTGGAGCTGAGAT
CCTAGAGGGCTCTGCCTCTGGAGTTGGGGATCTCAGTGGACTTCCTTCTGGAGAAGTTCTAGAGACCTCTGCCTCTGGAGTAGGAGACCT
CAGTGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGAC
CACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCT
TCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCC
TGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGG
AGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGA
GGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCT
AGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAG
CGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGC
TGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCC
TTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGG
AGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGA
AGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGA
CATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGA
GACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGG
GCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGAGGAGATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGC
CCCTGGAGTAGATGAGATCAGTGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGAGGAGATCAGCGGGCTTCCTTC
TGGAGAAGTTCTAGAGACTTCTACCTCTGCGGTAGGGGACCTCAGTGGACTTCCTTCTGGAGGAGAAGTTCTAGAGATTTCTGTCTCTGG
AGTAGAGGACATCAGTGGGCTTCCTTCTGGAGAGGTTGTAGAGACTTCTGCCTCTGGAATAGAGGATGTCAGTGAACTTCCTTCAGGAGA
AGGTCTAGAGACCTCTGCTTCTGGAGTAGAGGACCTCAGCAGGCTCCCTTCTGGAGAAGAAGTTCTAGAGATTTCTGCCTCTGGATTTGG
GGACCTCAGTGGACTTCCTTCTGGAGGAGAAGGTCTAGAGACCTCTGCTTCTGAAGTAGGGACTGACCTCAGTGGGCTTCCTTCTGGAAG
GGAGGGTCTAGAGACTTCAGCTTCTGGAGCTGAGGACCTCAGTGGGTTGCCTTCTGGAAAAGAAGACTTGGTGGGGTCAGCTTCTGGAGA
CTTGGACTTGGGCAAACTGCCTTCTGGAACTCTAGGAAGTGGGCAAGCTCCAGAAACAAGTGGTCTTCCCTCTGGATTTAGTGGTGAGTA
TTCTGGGGTGGACCTTGGAAGTGGCCCACCCTCTGGCCTGCCTGACTTTAGTGGACTTCCATCTGGATTCCCAACTGTTTCCCTAGTGGA
TTCTACATTGGTGGAAGTGGTCACAGCCTCCACTGCAAGTGAACTGGAAGGGAGGGGAACCATTGGCATCAGTGGTGCAGGAGAAATATC
TGGACTGCCCTCCAGTGAGCTGGACATTAGTGGGAGAGCTAGTGGACTCCCTTCAGGAACTGAACTCAGTGGCCAAGCATCTGGGTCTCC
TGATGTCAGTGGGGAAATACCTGGACTCTTTGGTGTCAGTGGACAGCCATCAGGGTTTCCTGACACTAGTGGGGAAACATCTGGAGTGAC
TGAGCTTAGCGGGCTGTCCTCTGGACAACCAGGTATTAGTGGAGAAGCATCTGGAGTTCTTTATGGCACTAGTCAACCCTTTGGCATAAC
TGATCTGAGTGGAGAAACATCTGGGGTCCCTGATCTCAGTGGGCAGCCTTCAGGGTTACCAGGGTTCAGTGGGGCAACATCAGGAGTCCC
TGACCTGGTTTCTGGTACCACGAGTGGCAGCGGTGAATCTTCTGGGATTACATTTGTGGACACCAGTTTGGTTGAAGTGGCCCCTACTAC
ATTTAAAGAAGAAGAAGGCTTAGGGTCTGTGGAACTCAGTGGCCTCCCTTCCGGAGAGGCAGATCTGTCAGGCAAATCTGGGATGGTGGA
TGTCAGTGGACAGTTTTCTGGAACAGTCGATTCCAGTGGGTTTACATCCCAGACTCCGGAATTCAGTGGCCTACCAAGTGGCATAGCTGA
GGTCAGTGGAGAATCCTCCAGAGCTGAGATTGGGAGCAGCCTGCCCTCGGGAGCATATTATGGCAGTGGAACTCCATCTAGTTTCCCCAC
TGTCTCTCTTGTAGACAGAACTTTGGTGGAATCTGTAACCCAGGCTCCAACAGCCCAAGAGGCAGGAGAAGGGCCTTCTGGCATTTTAGA
ACTCAGTGGTGCTCATTCTGGAGCACCAGACATGTCTGGGGAGCATTCTGGATTTCTGGACCTAAGTGGGCTGCAGTCCGGGCTGATAGA
GCCCAGCGGAGAGCCACCAGGTACTCCATATTTTAGTGGGGATTTTGCCAGCACCACCAATGTAAGTGGAGAATCCTCTGTAGCCATGGG
CACCAGTGGAGAGGCCTCAGGACTTCCAGAAGTTACTTTAATCACTTCTGAGTTCGTGGAGGGTGTTACTGAACCAACTATTTCTCAGGA
ACTAGGCCAAAGGCCCCCTGTGACACACACACCCCAGCTTTTTGAGTCCAGTGGAAAAGTCTCCACAGCTGGGGACATTAGTGGAGCTAC
CCCAGTGCTCCCTGGGTCTGGAGTAGAAGTATCATCAGTCCCAGAATCTAGCAGTGAGACGTCCGCCTATCCTGAAGCTGGGTTCGGGGC
ATCTGCCGCCCCTGAGGCCAGCAGAGAAGATTCTGGGTCCCCTGATCTGAGTGAAACCACCTCTGCATTCCACGAAGCTAACCTTGAGAG
ATCCTCTGGCCTAGGAGTGAGCGGCAGCACTTTGACATTTCAAGAAGGCGAGGCGTCCGCTGCCCCAGAAGTGAGTGGAGAATCCACCAC
CACCAGTGATGTGGGGACAGAGGCACCAGGCTTGCCTTCAGCCACTCCCACGGCTTCTGGAGACAGGACTGAAATCAGCGGAGACCTGTC
TGGTCACACCTCGCAGCTGGGCGTTGTCATCAGCACCAGCATCCCAGAGTCTGAGTGGACCCAGCAGACCCAGCGCCCTGCAGAGACGCA
TCTAGAAATTGAGTCCTCAAGCCTCCTGTACTCAGGAGAAGAGACTCACACAGTCGAAACAGCCACCTCCCCAACAGATGCTTCCATCCC
AGCTTCTCCGGAATGGAAACGTGAATCAGAATCAACTGCTGCAGCCCCCGCCAGGTCCTGTGCAGAGGAGCCCTGTGGAGCTGGGACCTG
CAAGGAGACAGAGGGACACGTCATATGCCTGTGCCCCCCTGGCTACACTGGCGAGCACTGTAACATAGACCAGGAGGTATGTGAGGAGGG
CTGGAACAAGTACCAGGGCCACTGTTACCGCCACTTCCCGGACCGCGAGACCTGGGTGGATGCTGAGCGCCGGTGTCGGGAGCAGCAGTC
ACACCTGAGCAGCATCGTCACCCCCGAGGAGCAGGAGTTTGTCAACAACAATGCCCAAGACTACCAGTGGATCGGCCTGAACGACAGGAC
CATCGAAGGGGACTTCCGCTGGTCAGATGGACACCCCATGCAATTTGAGAACTGGCGCCCCAACCAGCCTGACAACTTTTTTGCCGCTGG
AGAGGACTGTGTGGTGATGATCTGGCACGAGAAGGGCGAGTGGAATGATGTTCCCTGCAATTACCACCTCCCCTTCACGTGTAAAAAGGG
CACAGTGGCCTGCGGAGAGCCCCCTGTGGTGGAGCATGCCAGGACCTTCGGGCAGAAGAAGGACCGGTATGAGATCAATTCCCTGGTGCG
GTACCAGTGCACAGAGGGGTTTGTCCAGCGCCACATGCCCACCATCCGGTGCCAGCCCAGCGGGCACTGGGAGGAGCCTCAGATCACCTG
CACAGACCCCACCACCTACAAACGCAGACTACAGAAGCGGAGCTCACGGCACCCTCGGAGGAGCCGCCCCAGCACAGCCCACTGAGAAGA
GCTTCCAGGACGCACCCAGGACGCTGAGCCCAGGAGCCTGCCAGGCTGACGTGCATCCCACCCAGACGGTGTCCTCTTCTTGTCGCTTTT
TGTCATATAAGGAATCCCATTAAAGAAGGAAAAAAATAAATCCCACATTTGTGTATGCACCCACTCACCCCTCCAAATCAGCAAAACCGC
ATCTAATTTGTCCGCCGAATGCCAAAGCAAAGCAAACTTATTATAACCCTTGGACTGAGTTTAGAGACATTTCTTCAATTTCCCATCGTG
CCTTTCCAGGGACCAGTGCAGGGACAGGGGGAGAAGGGGAGGGGTTAAGTTAAATAAAGAAGATTATTTTTGTTTCCTGACTTTATCCAA
GAGCAGTGCAATCGTTGGTTATTTCACCTCCAGGGAGAGCTAGGGAGGAGGGAGGAGGGCTCCAAAGGAGCTGGAAGGAGCAGAGGCCTG
AGAGCAGGAAGAACTCGGAACCGCAGCTGAATGTATTGGATGAGAAGGAGCCAGGAGGGCTACACCATCTGTATGAGGGAAAAGCCTTGG
GGGAGAGGGGTGGGTTCCTGCCTCCTGCCGAGGGTAAGCCGGCAGGAGAGAGCCATCAGAGGGACCTCCGCTGCCTGGGAGTTGGGTTCC
CTCCAAGGGTCCCTCTTTCAGTGTCCTCTCTCTCACCTGGGTCTGCCACCCTAACAGGTGGCAACTCGGCAGGGCTGCTGGGGGCACTTC
CTGCCCAGTGGGGGGTGCCGCCCAACCTTCTCCCCTCCCCACCCCCGCCCCCGGGACCGTGCAGGCACCAGGGTTCCGTGCACCTATTTA

>417_417_1_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000352732_ACAN_chr15_89398083_ENST00000439576_length(amino acids)=1957AA_BP=358
MIKMNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMG
RVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMF
TYGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYT
PSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT
VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE
VLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV
EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET
AAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSG
GEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG
TDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLP
SGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFP
DTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVD
TSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY
GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTN
VSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSET
SAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASG
DRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSC
AEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQD
YQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKK

--------------------------------------------------------------
>417_417_2_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000355100_ACAN_chr15_89398083_ENST00000439576_length(transcript)=7211nt_BP=1011nt
TGTCAGGAGGGCGTAGTTTGCAAAACATCCCTCCCAGTGGTACTGATGCCTTTTCGCAGGTTCTGTCCTCTTCATTTGCAAGCCACTGCT
TTATCCACGAGGGTGCTCCCTACTTATGCCAGTGAATTAATTTTTGGCACAGATGAATCCTTCATATTTATCTGGATTTAGCTGGTAGCA
TTTGTCTCCTAAGACTTGGTCACAGAGGAATCCATGTGACCTTCAGGCCTTCTGCTCTAAACTGGCAGGAGATCCTGTTTCTACTCACAG
CGTCCGAGGGTCTGGTGGCCGAGCCCTGAGGGGCGCTGTTGCTCCCAGGTGGCAGAATTCAGCATCAGAGAGCCACACAGCTGAAAGAGA
TGGATGGCTTTTAGGTTTGTTTGAATAAGAGATCTGACCTGACCGGCCCAACTGTACAACTCTTCAAGGAAAATTCGTATTTGCAGTGGG
AAGAATAAGTAACATTGATCAAGATGAATGCCATGCTGGAGACTCCCGAACTCCCAGCCGTGTTTGATGGAGTGAAGCTGGCTGCAGTGG
CTGCTGTGCTGTACGTGATCGTCCGGTGTTTGAACCTGAAGAGCCCCACAGCCCCACCTGACCTCTACTTCCAGGACTCGGGGCTCTCAC
GCTTTCTGCTCAAGTCCTGTCCTCTTCTGACCAAAGAATACATTCCACCGTTGATCTGGGGGAAAAGTGGACACATCCAGACAGCCTTGT
ATGGGAAGATGGGAAGGGTGAGGTCGCCACATCCTTATGGGCACCGGAAGTTCATCACTATGTCTGATGGAGCCACTTCTACATTCGACC
TCTTCGAGCCCTTGGCTGAGCACTGTGTTGGAGATGATATCACCATGGTCATCTGCCCTGGAATTGCCAATCACAGCGAGAAGCAATACA
TCCGCACTTTCGTTGACTACGCCCAGAAAAATGGCTATCGGTGCGCCGTGCTGAACCACCTGGGTGCCCTGCCCAACATTGAATTGACCT
CGCCACGCATGTTCACCTATGGGATCCTTCCTACTTGGCCTCCCACTGGCGCAGCAACAGAGGAAAGTACAGAAGGCCCTTCTGCAACTG
AAGTGCCCTCTGCCTCAGAGGAACCATCCCCCTCAGAGGTGCCATTCCCCTCAGAGGAGCCATCCCCCTCAGAGGAACCATTCCCCTCAG
TGAGGCCATTCCCCTCAGTGGAGCTGTTCCCCTCAGAGGAGCCATTCCCCTCCAAGGAGCCATCCCCCTCAGAGGAACCATCAGCCTCGG
AAGAGCCGTATACACCTTCACCCCCCGTGCCCAGCTGGACTGAGCTGCCCAGCTCTGGGGAGGAATCTGGGGCCCCTGATGTCAGTGGTG
ACTTCACAGGCAGTGGAGATGTTTCAGGACACCTTGACTTCAGTGGGCAGCTGTCAGGGGACAGGGCAAGTGGACTGCCCTCTGGAGACC
TGGACTCCAGTGGTCTTACTTCCACAGTGGGCTCAGGCCTGCCTGTGGAAAGTGGACTACCCTCAGGGGATGAAGAGAGAATTGAGTGGC
CCAGCACTCCTACGGTTGGTGAACTGCCCTCTGGAGCTGAGATCCTAGAGGGCTCTGCCTCTGGAGTTGGGGATCTCAGTGGACTTCCTT
CTGGAGAAGTTCTAGAGACCTCTGCCTCTGGAGTAGGAGACCTCAGTGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAG
TAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAG
TTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACA
TCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGA
CCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGC
TTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCC
CTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTG
GAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAG
AGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTC
TAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCA
GCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTG
CTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTC
CTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTG
GAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAG
AAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGAGG
AGATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGATGAGATCAGTGGGCTTCCTTCTGGAGAAGTTCTAG
AGACTACTGCCCCTGGAGTAGAGGAGATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTTCTACCTCTGCGGTAGGGGACCTCAGTG
GACTTCCTTCTGGAGGAGAAGTTCTAGAGATTTCTGTCTCTGGAGTAGAGGACATCAGTGGGCTTCCTTCTGGAGAGGTTGTAGAGACTT
CTGCCTCTGGAATAGAGGATGTCAGTGAACTTCCTTCAGGAGAAGGTCTAGAGACCTCTGCTTCTGGAGTAGAGGACCTCAGCAGGCTCC
CTTCTGGAGAAGAAGTTCTAGAGATTTCTGCCTCTGGATTTGGGGACCTCAGTGGACTTCCTTCTGGAGGAGAAGGTCTAGAGACCTCTG
CTTCTGAAGTAGGGACTGACCTCAGTGGGCTTCCTTCTGGAAGGGAGGGTCTAGAGACTTCAGCTTCTGGAGCTGAGGACCTCAGTGGGT
TGCCTTCTGGAAAAGAAGACTTGGTGGGGTCAGCTTCTGGAGACTTGGACTTGGGCAAACTGCCTTCTGGAACTCTAGGAAGTGGGCAAG
CTCCAGAAACAAGTGGTCTTCCCTCTGGATTTAGTGGTGAGTATTCTGGGGTGGACCTTGGAAGTGGCCCACCCTCTGGCCTGCCTGACT
TTAGTGGACTTCCATCTGGATTCCCAACTGTTTCCCTAGTGGATTCTACATTGGTGGAAGTGGTCACAGCCTCCACTGCAAGTGAACTGG
AAGGGAGGGGAACCATTGGCATCAGTGGTGCAGGAGAAATATCTGGACTGCCCTCCAGTGAGCTGGACATTAGTGGGAGAGCTAGTGGAC
TCCCTTCAGGAACTGAACTCAGTGGCCAAGCATCTGGGTCTCCTGATGTCAGTGGGGAAATACCTGGACTCTTTGGTGTCAGTGGACAGC
CATCAGGGTTTCCTGACACTAGTGGGGAAACATCTGGAGTGACTGAGCTTAGCGGGCTGTCCTCTGGACAACCAGGTATTAGTGGAGAAG
CATCTGGAGTTCTTTATGGCACTAGTCAACCCTTTGGCATAACTGATCTGAGTGGAGAAACATCTGGGGTCCCTGATCTCAGTGGGCAGC
CTTCAGGGTTACCAGGGTTCAGTGGGGCAACATCAGGAGTCCCTGACCTGGTTTCTGGTACCACGAGTGGCAGCGGTGAATCTTCTGGGA
TTACATTTGTGGACACCAGTTTGGTTGAAGTGGCCCCTACTACATTTAAAGAAGAAGAAGGCTTAGGGTCTGTGGAACTCAGTGGCCTCC
CTTCCGGAGAGGCAGATCTGTCAGGCAAATCTGGGATGGTGGATGTCAGTGGACAGTTTTCTGGAACAGTCGATTCCAGTGGGTTTACAT
CCCAGACTCCGGAATTCAGTGGCCTACCAAGTGGCATAGCTGAGGTCAGTGGAGAATCCTCCAGAGCTGAGATTGGGAGCAGCCTGCCCT
CGGGAGCATATTATGGCAGTGGAACTCCATCTAGTTTCCCCACTGTCTCTCTTGTAGACAGAACTTTGGTGGAATCTGTAACCCAGGCTC
CAACAGCCCAAGAGGCAGGAGAAGGGCCTTCTGGCATTTTAGAACTCAGTGGTGCTCATTCTGGAGCACCAGACATGTCTGGGGAGCATT
CTGGATTTCTGGACCTAAGTGGGCTGCAGTCCGGGCTGATAGAGCCCAGCGGAGAGCCACCAGGTACTCCATATTTTAGTGGGGATTTTG
CCAGCACCACCAATGTAAGTGGAGAATCCTCTGTAGCCATGGGCACCAGTGGAGAGGCCTCAGGACTTCCAGAAGTTACTTTAATCACTT
CTGAGTTCGTGGAGGGTGTTACTGAACCAACTATTTCTCAGGAACTAGGCCAAAGGCCCCCTGTGACACACACACCCCAGCTTTTTGAGT
CCAGTGGAAAAGTCTCCACAGCTGGGGACATTAGTGGAGCTACCCCAGTGCTCCCTGGGTCTGGAGTAGAAGTATCATCAGTCCCAGAAT
CTAGCAGTGAGACGTCCGCCTATCCTGAAGCTGGGTTCGGGGCATCTGCCGCCCCTGAGGCCAGCAGAGAAGATTCTGGGTCCCCTGATC
TGAGTGAAACCACCTCTGCATTCCACGAAGCTAACCTTGAGAGATCCTCTGGCCTAGGAGTGAGCGGCAGCACTTTGACATTTCAAGAAG
GCGAGGCGTCCGCTGCCCCAGAAGTGAGTGGAGAATCCACCACCACCAGTGATGTGGGGACAGAGGCACCAGGCTTGCCTTCAGCCACTC
CCACGGCTTCTGGAGACAGGACTGAAATCAGCGGAGACCTGTCTGGTCACACCTCGCAGCTGGGCGTTGTCATCAGCACCAGCATCCCAG
AGTCTGAGTGGACCCAGCAGACCCAGCGCCCTGCAGAGACGCATCTAGAAATTGAGTCCTCAAGCCTCCTGTACTCAGGAGAAGAGACTC
ACACAGTCGAAACAGCCACCTCCCCAACAGATGCTTCCATCCCAGCTTCTCCGGAATGGAAACGTGAATCAGAATCAACTGCTGCAGCCC
CCGCCAGGTCCTGTGCAGAGGAGCCCTGTGGAGCTGGGACCTGCAAGGAGACAGAGGGACACGTCATATGCCTGTGCCCCCCTGGCTACA
CTGGCGAGCACTGTAACATAGACCAGGAGGTATGTGAGGAGGGCTGGAACAAGTACCAGGGCCACTGTTACCGCCACTTCCCGGACCGCG
AGACCTGGGTGGATGCTGAGCGCCGGTGTCGGGAGCAGCAGTCACACCTGAGCAGCATCGTCACCCCCGAGGAGCAGGAGTTTGTCAACA
ACAATGCCCAAGACTACCAGTGGATCGGCCTGAACGACAGGACCATCGAAGGGGACTTCCGCTGGTCAGATGGACACCCCATGCAATTTG
AGAACTGGCGCCCCAACCAGCCTGACAACTTTTTTGCCGCTGGAGAGGACTGTGTGGTGATGATCTGGCACGAGAAGGGCGAGTGGAATG
ATGTTCCCTGCAATTACCACCTCCCCTTCACGTGTAAAAAGGGCACAGTGGCCTGCGGAGAGCCCCCTGTGGTGGAGCATGCCAGGACCT
TCGGGCAGAAGAAGGACCGGTATGAGATCAATTCCCTGGTGCGGTACCAGTGCACAGAGGGGTTTGTCCAGCGCCACATGCCCACCATCC
GGTGCCAGCCCAGCGGGCACTGGGAGGAGCCTCAGATCACCTGCACAGACCCCACCACCTACAAACGCAGACTACAGAAGCGGAGCTCAC
GGCACCCTCGGAGGAGCCGCCCCAGCACAGCCCACTGAGAAGAGCTTCCAGGACGCACCCAGGACGCTGAGCCCAGGAGCCTGCCAGGCT
GACGTGCATCCCACCCAGACGGTGTCCTCTTCTTGTCGCTTTTTGTCATATAAGGAATCCCATTAAAGAAGGAAAAAAATAAATCCCACA
TTTGTGTATGCACCCACTCACCCCTCCAAATCAGCAAAACCGCATCTAATTTGTCCGCCGAATGCCAAAGCAAAGCAAACTTATTATAAC
CCTTGGACTGAGTTTAGAGACATTTCTTCAATTTCCCATCGTGCCTTTCCAGGGACCAGTGCAGGGACAGGGGGAGAAGGGGAGGGGTTA
AGTTAAATAAAGAAGATTATTTTTGTTTCCTGACTTTATCCAAGAGCAGTGCAATCGTTGGTTATTTCACCTCCAGGGAGAGCTAGGGAG
GAGGGAGGAGGGCTCCAAAGGAGCTGGAAGGAGCAGAGGCCTGAGAGCAGGAAGAACTCGGAACCGCAGCTGAATGTATTGGATGAGAAG
GAGCCAGGAGGGCTACACCATCTGTATGAGGGAAAAGCCTTGGGGGAGAGGGGTGGGTTCCTGCCTCCTGCCGAGGGTAAGCCGGCAGGA
GAGAGCCATCAGAGGGACCTCCGCTGCCTGGGAGTTGGGTTCCCTCCAAGGGTCCCTCTTTCAGTGTCCTCTCTCTCACCTGGGTCTGCC
ACCCTAACAGGTGGCAACTCGGCAGGGCTGCTGGGGGCACTTCCTGCCCAGTGGGGGGTGCCGCCCAACCTTCTCCCCTCCCCACCCCCG
CCCCCGGGACCGTGCAGGCACCAGGGTTCCGTGCACCTATTTATATTTTTGAAAACTGAAGATTATAATATTATAATAATAATAAAGACA

>417_417_2_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000355100_ACAN_chr15_89398083_ENST00000439576_length(amino acids)=1957AA_BP=358
MIKMNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMG
RVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMF
TYGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYT
PSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT
VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE
VLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV
EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET
AAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSG
GEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG
TDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLP
SGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFP
DTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVD
TSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY
GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTN
VSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSET
SAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASG
DRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSC
AEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQD
YQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKK

--------------------------------------------------------------
>417_417_3_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000565973_ACAN_chr15_89398083_ENST00000439576_length(transcript)=7479nt_BP=1279nt
GGGCGGGGCCGGTAGCGGCGGGAGCTGCACTGGCCAGGGGTTCCGGCTGTATATCCATGAGCGCCGCTGGCAGCCGGGGAGCTGCAGGAA
CCAGACTGGGGGCGAGCTGAGCACCTGTAGTCAATCACACGCAGAAATAATAATGATACTTATGTTAGAAGATTGTTTTGAGAAGTGCAT
GGAGTTACTACATCTGAAGCATTTAGAACAGTACCTGGCACAGGAGGTTAGAGTGATGTCTTTCGTCCCTGTGGGGAGTGAGGTGGAATG
TCAGGAGGGCGTAGTTTGCAAAACATCCCTCCCAGTGGTACTGATGCCTTTTCGCAGGTTCTGTCCTCTTCATTTGCAAGCCACTGCTTT
ATCCACGAGGGTGCTCCCTACTTATGCCAGTGAATTAATTTTTGGCACAGATGAATCCTTCATATTTATCTGGATTTAGCTGGTAGCATT
TGTCTCCTAAGACTTGGTCACAGAGGAATCCATGTGACCTTCAGGCCTTCTGCTCTAAACTGGCAGGAGATCCTGTTTCTACTCACAGCG
TCCGAGGGTCTGGTGGCCGAGCCCTGAGGGGCGCTGTTGCTCCCAGGTGGCAGAATTCAGCATCAGAGAGCCACACAGCTGAAAGAGATG
GATGGCTTTTAGGTTTGTTTGAATAAGAGATCTGACCTGACCGGCCCAACTGTACAACTCTTCAAGGAAAATTCGTATTTGCAGTGGGAA
GAATAAGTAACATTGATCAAGATGAATGCCATGCTGGAGACTCCCGAACTCCCAGCCGTGTTTGATGGAGTGAAGCTGGCTGCAGTGGCT
GCTGTGCTGTACGTGATCGTCCGGTGTTTGAACCTGAAGAGCCCCACAGCCCCACCTGACCTCTACTTCCAGGACTCGGGGCTCTCACGC
TTTCTGCTCAAGTCCTGTCCTCTTCTGACCAAAGAATACATTCCACCGTTGATCTGGGGGAAAAGTGGACACATCCAGACAGCCTTGTAT
GGGAAGATGGGAAGGGTGAGGTCGCCACATCCTTATGGGCACCGGAAGTTCATCACTATGTCTGATGGAGCCACTTCTACATTCGACCTC
TTCGAGCCCTTGGCTGAGCACTGTGTTGGAGATGATATCACCATGGTCATCTGCCCTGGAATTGCCAATCACAGCGAGAAGCAATACATC
CGCACTTTCGTTGACTACGCCCAGAAAAATGGCTATCGGTGCGCCGTGCTGAACCACCTGGGTGCCCTGCCCAACATTGAATTGACCTCG
CCACGCATGTTCACCTATGGGATCCTTCCTACTTGGCCTCCCACTGGCGCAGCAACAGAGGAAAGTACAGAAGGCCCTTCTGCAACTGAA
GTGCCCTCTGCCTCAGAGGAACCATCCCCCTCAGAGGTGCCATTCCCCTCAGAGGAGCCATCCCCCTCAGAGGAACCATTCCCCTCAGTG
AGGCCATTCCCCTCAGTGGAGCTGTTCCCCTCAGAGGAGCCATTCCCCTCCAAGGAGCCATCCCCCTCAGAGGAACCATCAGCCTCGGAA
GAGCCGTATACACCTTCACCCCCCGTGCCCAGCTGGACTGAGCTGCCCAGCTCTGGGGAGGAATCTGGGGCCCCTGATGTCAGTGGTGAC
TTCACAGGCAGTGGAGATGTTTCAGGACACCTTGACTTCAGTGGGCAGCTGTCAGGGGACAGGGCAAGTGGACTGCCCTCTGGAGACCTG
GACTCCAGTGGTCTTACTTCCACAGTGGGCTCAGGCCTGCCTGTGGAAAGTGGACTACCCTCAGGGGATGAAGAGAGAATTGAGTGGCCC
AGCACTCCTACGGTTGGTGAACTGCCCTCTGGAGCTGAGATCCTAGAGGGCTCTGCCTCTGGAGTTGGGGATCTCAGTGGACTTCCTTCT
GGAGAAGTTCTAGAGACCTCTGCCTCTGGAGTAGGAGACCTCAGTGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTA
GAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTT
CTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATC
AGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACC
ACTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTT
CCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCT
GGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGA
GAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAG
GACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACCGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTA
GAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGC
GGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCT
GCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCT
TCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGA
GTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAA
GTTCTAGAGACTGCTGCCCCTGGAGTAGAGGACATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGAGGAG
ATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTACTGCCCCTGGAGTAGATGAGATCAGTGGGCTTCCTTCTGGAGAAGTTCTAGAG
ACTACTGCCCCTGGAGTAGAGGAGATCAGCGGGCTTCCTTCTGGAGAAGTTCTAGAGACTTCTACCTCTGCGGTAGGGGACCTCAGTGGA
CTTCCTTCTGGAGGAGAAGTTCTAGAGATTTCTGTCTCTGGAGTAGAGGACATCAGTGGGCTTCCTTCTGGAGAGGTTGTAGAGACTTCT
GCCTCTGGAATAGAGGATGTCAGTGAACTTCCTTCAGGAGAAGGTCTAGAGACCTCTGCTTCTGGAGTAGAGGACCTCAGCAGGCTCCCT
TCTGGAGAAGAAGTTCTAGAGATTTCTGCCTCTGGATTTGGGGACCTCAGTGGACTTCCTTCTGGAGGAGAAGGTCTAGAGACCTCTGCT
TCTGAAGTAGGGACTGACCTCAGTGGGCTTCCTTCTGGAAGGGAGGGTCTAGAGACTTCAGCTTCTGGAGCTGAGGACCTCAGTGGGTTG
CCTTCTGGAAAAGAAGACTTGGTGGGGTCAGCTTCTGGAGACTTGGACTTGGGCAAACTGCCTTCTGGAACTCTAGGAAGTGGGCAAGCT
CCAGAAACAAGTGGTCTTCCCTCTGGATTTAGTGGTGAGTATTCTGGGGTGGACCTTGGAAGTGGCCCACCCTCTGGCCTGCCTGACTTT
AGTGGACTTCCATCTGGATTCCCAACTGTTTCCCTAGTGGATTCTACATTGGTGGAAGTGGTCACAGCCTCCACTGCAAGTGAACTGGAA
GGGAGGGGAACCATTGGCATCAGTGGTGCAGGAGAAATATCTGGACTGCCCTCCAGTGAGCTGGACATTAGTGGGAGAGCTAGTGGACTC
CCTTCAGGAACTGAACTCAGTGGCCAAGCATCTGGGTCTCCTGATGTCAGTGGGGAAATACCTGGACTCTTTGGTGTCAGTGGACAGCCA
TCAGGGTTTCCTGACACTAGTGGGGAAACATCTGGAGTGACTGAGCTTAGCGGGCTGTCCTCTGGACAACCAGGTATTAGTGGAGAAGCA
TCTGGAGTTCTTTATGGCACTAGTCAACCCTTTGGCATAACTGATCTGAGTGGAGAAACATCTGGGGTCCCTGATCTCAGTGGGCAGCCT
TCAGGGTTACCAGGGTTCAGTGGGGCAACATCAGGAGTCCCTGACCTGGTTTCTGGTACCACGAGTGGCAGCGGTGAATCTTCTGGGATT
ACATTTGTGGACACCAGTTTGGTTGAAGTGGCCCCTACTACATTTAAAGAAGAAGAAGGCTTAGGGTCTGTGGAACTCAGTGGCCTCCCT
TCCGGAGAGGCAGATCTGTCAGGCAAATCTGGGATGGTGGATGTCAGTGGACAGTTTTCTGGAACAGTCGATTCCAGTGGGTTTACATCC
CAGACTCCGGAATTCAGTGGCCTACCAAGTGGCATAGCTGAGGTCAGTGGAGAATCCTCCAGAGCTGAGATTGGGAGCAGCCTGCCCTCG
GGAGCATATTATGGCAGTGGAACTCCATCTAGTTTCCCCACTGTCTCTCTTGTAGACAGAACTTTGGTGGAATCTGTAACCCAGGCTCCA
ACAGCCCAAGAGGCAGGAGAAGGGCCTTCTGGCATTTTAGAACTCAGTGGTGCTCATTCTGGAGCACCAGACATGTCTGGGGAGCATTCT
GGATTTCTGGACCTAAGTGGGCTGCAGTCCGGGCTGATAGAGCCCAGCGGAGAGCCACCAGGTACTCCATATTTTAGTGGGGATTTTGCC
AGCACCACCAATGTAAGTGGAGAATCCTCTGTAGCCATGGGCACCAGTGGAGAGGCCTCAGGACTTCCAGAAGTTACTTTAATCACTTCT
GAGTTCGTGGAGGGTGTTACTGAACCAACTATTTCTCAGGAACTAGGCCAAAGGCCCCCTGTGACACACACACCCCAGCTTTTTGAGTCC
AGTGGAAAAGTCTCCACAGCTGGGGACATTAGTGGAGCTACCCCAGTGCTCCCTGGGTCTGGAGTAGAAGTATCATCAGTCCCAGAATCT
AGCAGTGAGACGTCCGCCTATCCTGAAGCTGGGTTCGGGGCATCTGCCGCCCCTGAGGCCAGCAGAGAAGATTCTGGGTCCCCTGATCTG
AGTGAAACCACCTCTGCATTCCACGAAGCTAACCTTGAGAGATCCTCTGGCCTAGGAGTGAGCGGCAGCACTTTGACATTTCAAGAAGGC
GAGGCGTCCGCTGCCCCAGAAGTGAGTGGAGAATCCACCACCACCAGTGATGTGGGGACAGAGGCACCAGGCTTGCCTTCAGCCACTCCC
ACGGCTTCTGGAGACAGGACTGAAATCAGCGGAGACCTGTCTGGTCACACCTCGCAGCTGGGCGTTGTCATCAGCACCAGCATCCCAGAG
TCTGAGTGGACCCAGCAGACCCAGCGCCCTGCAGAGACGCATCTAGAAATTGAGTCCTCAAGCCTCCTGTACTCAGGAGAAGAGACTCAC
ACAGTCGAAACAGCCACCTCCCCAACAGATGCTTCCATCCCAGCTTCTCCGGAATGGAAACGTGAATCAGAATCAACTGCTGCAGCCCCC
GCCAGGTCCTGTGCAGAGGAGCCCTGTGGAGCTGGGACCTGCAAGGAGACAGAGGGACACGTCATATGCCTGTGCCCCCCTGGCTACACT
GGCGAGCACTGTAACATAGACCAGGAGGTATGTGAGGAGGGCTGGAACAAGTACCAGGGCCACTGTTACCGCCACTTCCCGGACCGCGAG
ACCTGGGTGGATGCTGAGCGCCGGTGTCGGGAGCAGCAGTCACACCTGAGCAGCATCGTCACCCCCGAGGAGCAGGAGTTTGTCAACAAC
AATGCCCAAGACTACCAGTGGATCGGCCTGAACGACAGGACCATCGAAGGGGACTTCCGCTGGTCAGATGGACACCCCATGCAATTTGAG
AACTGGCGCCCCAACCAGCCTGACAACTTTTTTGCCGCTGGAGAGGACTGTGTGGTGATGATCTGGCACGAGAAGGGCGAGTGGAATGAT
GTTCCCTGCAATTACCACCTCCCCTTCACGTGTAAAAAGGGCACAGTGGCCTGCGGAGAGCCCCCTGTGGTGGAGCATGCCAGGACCTTC
GGGCAGAAGAAGGACCGGTATGAGATCAATTCCCTGGTGCGGTACCAGTGCACAGAGGGGTTTGTCCAGCGCCACATGCCCACCATCCGG
TGCCAGCCCAGCGGGCACTGGGAGGAGCCTCAGATCACCTGCACAGACCCCACCACCTACAAACGCAGACTACAGAAGCGGAGCTCACGG
CACCCTCGGAGGAGCCGCCCCAGCACAGCCCACTGAGAAGAGCTTCCAGGACGCACCCAGGACGCTGAGCCCAGGAGCCTGCCAGGCTGA
CGTGCATCCCACCCAGACGGTGTCCTCTTCTTGTCGCTTTTTGTCATATAAGGAATCCCATTAAAGAAGGAAAAAAATAAATCCCACATT
TGTGTATGCACCCACTCACCCCTCCAAATCAGCAAAACCGCATCTAATTTGTCCGCCGAATGCCAAAGCAAAGCAAACTTATTATAACCC
TTGGACTGAGTTTAGAGACATTTCTTCAATTTCCCATCGTGCCTTTCCAGGGACCAGTGCAGGGACAGGGGGAGAAGGGGAGGGGTTAAG
TTAAATAAAGAAGATTATTTTTGTTTCCTGACTTTATCCAAGAGCAGTGCAATCGTTGGTTATTTCACCTCCAGGGAGAGCTAGGGAGGA
GGGAGGAGGGCTCCAAAGGAGCTGGAAGGAGCAGAGGCCTGAGAGCAGGAAGAACTCGGAACCGCAGCTGAATGTATTGGATGAGAAGGA
GCCAGGAGGGCTACACCATCTGTATGAGGGAAAAGCCTTGGGGGAGAGGGGTGGGTTCCTGCCTCCTGCCGAGGGTAAGCCGGCAGGAGA
GAGCCATCAGAGGGACCTCCGCTGCCTGGGAGTTGGGTTCCCTCCAAGGGTCCCTCTTTCAGTGTCCTCTCTCTCACCTGGGTCTGCCAC
CCTAACAGGTGGCAACTCGGCAGGGCTGCTGGGGGCACTTCCTGCCCAGTGGGGGGTGCCGCCCAACCTTCTCCCCTCCCCACCCCCGCC
CCCGGGACCGTGCAGGCACCAGGGTTCCGTGCACCTATTTATATTTTTGAAAACTGAAGATTATAATATTATAATAATAATAAAGACATT

>417_417_3_ABHD2-ACAN_ABHD2_chr15_89698765_ENST00000565973_ACAN_chr15_89398083_ENST00000439576_length(amino acids)=1957AA_BP=358
MIKMNAMLETPELPAVFDGVKLAAVAAVLYVIVRCLNLKSPTAPPDLYFQDSGLSRFLLKSCPLLTKEYIPPLIWGKSGHIQTALYGKMG
RVRSPHPYGHRKFITMSDGATSTFDLFEPLAEHCVGDDITMVICPGIANHSEKQYIRTFVDYAQKNGYRCAVLNHLGALPNIELTSPRMF
TYGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYT
PSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT
VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETT
APGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGE
VLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISG
LPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGV
EDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLET
AAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSG
GEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVG
TDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLP
SGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFP
DTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVD
TSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYY
GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTN
VSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSET
SAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTTTSDVGTEAPGLPSATPTASG
DRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESESTAAAPARSC
AEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQD
YQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKK

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Fusion Gene PPI Analysis for ABHD2-ACAN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABHD2-ACAN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABHD2-ACAN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC1842149Spondyloepiphyseal Dysplasia, Kimberley Type3CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC3665488Familial Osteochondritis Dissecans3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC2748544Spondyloepimetaphyseal Dysplasia, Aggrecan Type2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0003873Rheumatoid Arthritis1CTD_human
TgeneC0004681Bagassosis1CTD_human
TgeneC0032273Pneumoconiosis1CTD_human
TgeneC0238288Muscular Dystrophy, Facioscapulohumeral1CTD_human