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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CASC4-CTDSPL2 (FusionGDB2 ID:HG113201TG51496)

Fusion Gene Summary for CASC4-CTDSPL2

check button Fusion gene summary
Fusion gene informationFusion gene name: CASC4-CTDSPL2
Fusion gene ID: hg113201tg51496
HgeneTgene
Gene symbol

CASC4

CTDSPL2

Gene ID

113201

51496

Gene namegolgi membrane protein 2CTD small phosphatase like 2
SynonymsCASC4|H63HSPC058|HSPC129|SCP4
Cytomap('CASC4')('CTDSPL2')

15q15.3

15q15.3-q21.1

Type of geneprotein-codingprotein-coding
Descriptionprotein CASC4cancer susceptibility 4cancer susceptibility candidate 4cancer susceptibility candidate gene 4 proteingene associated with HER-2/neu overexpressionCTD small phosphatase-like protein 2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2CTDSP-like 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000360824, ENST00000429162, 
ENST00000299957, ENST00000345795, 
ENST00000345795, ENST00000360824, 
ENST00000429162, ENST00000299957, 
Fusion gene scores* DoF score12 X 9 X 6=6488 X 10 X 4=320
# samples 1411
** MAII scorelog2(14/648*10)=-2.21056698593966
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/320*10)=-1.5405683813627
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CASC4 [Title/Abstract] AND CTDSPL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCASC4(44581554)-CTDSPL2(44751189), # samples:1
CASC4(44630515)-CTDSPL2(44788578), # samples:1
Anticipated loss of major functional domain due to fusion event.CASC4-CTDSPL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CASC4-CTDSPL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTDSPL2-CASC4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CTDSPL2-CASC4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CTDSPL2-CASC4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CTDSPL2-CASC4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CASC4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CTDSPL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A3XT-01ACASC4chr15

44581554

+CTDSPL2chr15

44751189

+
ChimerDB4KIRCTCGA-B0-4698-01ACASC4chr15

44630515

+CTDSPL2chr15

44788578

+


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Fusion Gene ORF analysis for CASC4-CTDSPL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000360824ENST00000260327CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
3UTR-3CDSENST00000360824ENST00000396780CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
3UTR-3CDSENST00000360824ENST00000558373CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
3UTR-3CDSENST00000360824ENST00000558966CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
3UTR-3UTRENST00000360824ENST00000561189CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
3UTR-5UTRENST00000429162ENST00000260327CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
3UTR-5UTRENST00000429162ENST00000396780CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
3UTR-5UTRENST00000429162ENST00000558966CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
3UTR-intronENST00000429162ENST00000558373CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
3UTR-intronENST00000429162ENST00000561189CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-3UTRENST00000299957ENST00000561189CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
5CDS-3UTRENST00000345795ENST00000561189CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
5CDS-5UTRENST00000299957ENST00000260327CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000299957ENST00000396780CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000299957ENST00000558966CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000345795ENST00000260327CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000345795ENST00000396780CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000345795ENST00000558966CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000360824ENST00000260327CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000360824ENST00000396780CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-5UTRENST00000360824ENST00000558966CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000299957ENST00000558373CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000299957ENST00000561189CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000345795ENST00000558373CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000345795ENST00000561189CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000360824ENST00000558373CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
5CDS-intronENST00000360824ENST00000561189CASC4chr15

44581554

+CTDSPL2chr15

44751189

+
In-frameENST00000299957ENST00000260327CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000299957ENST00000396780CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000299957ENST00000558373CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000299957ENST00000558966CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000345795ENST00000260327CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000345795ENST00000396780CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000345795ENST00000558373CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
In-frameENST00000345795ENST00000558966CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
intron-3CDSENST00000429162ENST00000260327CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
intron-3CDSENST00000429162ENST00000396780CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
intron-3CDSENST00000429162ENST00000558373CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
intron-3CDSENST00000429162ENST00000558966CASC4chr15

44630515

+CTDSPL2chr15

44788578

+
intron-3UTRENST00000429162ENST00000561189CASC4chr15

44630515

+CTDSPL2chr15

44788578

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000299957CASC4chr1544630515+ENST00000260327CTDSPL2chr1544788578+667511012991810503
ENST00000299957CASC4chr1544630515+ENST00000396780CTDSPL2chr1544788578+486911012991810503
ENST00000299957CASC4chr1544630515+ENST00000558966CTDSPL2chr1544788578+218011012991810503
ENST00000299957CASC4chr1544630515+ENST00000558373CTDSPL2chr1544788578+486911012991810503
ENST00000345795CASC4chr1544630515+ENST00000260327CTDSPL2chr1544788578+664610722701781503
ENST00000345795CASC4chr1544630515+ENST00000396780CTDSPL2chr1544788578+484010722701781503
ENST00000345795CASC4chr1544630515+ENST00000558966CTDSPL2chr1544788578+215110722701781503
ENST00000345795CASC4chr1544630515+ENST00000558373CTDSPL2chr1544788578+484010722701781503

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000299957ENST00000260327CASC4chr1544630515+CTDSPL2chr1544788578+9.88E-050.9999012
ENST00000299957ENST00000396780CASC4chr1544630515+CTDSPL2chr1544788578+0.0001122380.9998877
ENST00000299957ENST00000558966CASC4chr1544630515+CTDSPL2chr1544788578+0.0009529560.999047
ENST00000299957ENST00000558373CASC4chr1544630515+CTDSPL2chr1544788578+0.0001122380.9998877
ENST00000345795ENST00000260327CASC4chr1544630515+CTDSPL2chr1544788578+9.90E-050.99990094
ENST00000345795ENST00000396780CASC4chr1544630515+CTDSPL2chr1544788578+0.000114420.99988556
ENST00000345795ENST00000558966CASC4chr1544630515+CTDSPL2chr1544788578+0.0009715750.99902844
ENST00000345795ENST00000558373CASC4chr1544630515+CTDSPL2chr1544788578+0.000114420.99988556

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Fusion Genomic Features for CASC4-CTDSPL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CASC4chr1544581554+CTDSPL2chr1544751188+2.71E-121
CASC4chr1544630515+CTDSPL2chr1544788577+5.87E-081
CASC4chr1544581554+CTDSPL2chr1544751188+2.71E-121
CASC4chr1544630515+CTDSPL2chr1544788577+5.87E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CASC4-CTDSPL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:44581554/chr15:44751189)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCASC4chr15:44630515chr15:44788578ENST00000299957+61035_198267437.0Coiled coilOntology_term=ECO:0000255
HgeneCASC4chr15:44630515chr15:44788578ENST00000345795+6935_198267381.0Coiled coilOntology_term=ECO:0000255
HgeneCASC4chr15:44630515chr15:44788578ENST00000360824+5835_198237802.3333333333334Coiled coilOntology_term=ECO:0000255
HgeneCASC4chr15:44630515chr15:44788578ENST00000299957+6101_14267437.0Topological domainCytoplasmic
HgeneCASC4chr15:44630515chr15:44788578ENST00000345795+691_14267381.0Topological domainCytoplasmic
HgeneCASC4chr15:44630515chr15:44788578ENST00000360824+581_14237802.3333333333334Topological domainCytoplasmic
HgeneCASC4chr15:44630515chr15:44788578ENST00000299957+61015_35267437.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCASC4chr15:44630515chr15:44788578ENST00000345795+6915_35267381.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCASC4chr15:44630515chr15:44788578ENST00000360824+5815_35237802.3333333333334TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneCTDSPL2chr15:44630515chr15:44788578ENST00000260327413283_442230467.0DomainFCP1 homology
TgeneCTDSPL2chr15:44630515chr15:44788578ENST00000396780312283_442158395.0DomainFCP1 homology
TgeneCTDSPL2chr15:44630515chr15:44788578ENST00000558373211283_442158395.0DomainFCP1 homology
TgeneCTDSPL2chr15:44630515chr15:44788578ENST00000558966413283_442230467.0DomainFCP1 homology

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCASC4chr15:44630515chr15:44788578ENST00000299957+61036_436267437.0Topological domainLumenal
HgeneCASC4chr15:44630515chr15:44788578ENST00000345795+6936_436267381.0Topological domainLumenal
HgeneCASC4chr15:44630515chr15:44788578ENST00000360824+5836_436237802.3333333333334Topological domainLumenal


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Fusion Gene Sequence for CASC4-CTDSPL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13166_13166_1_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000260327_length(transcript)=6675nt_BP=1101nt
CCGTGAGGTGTTGGGTTTGGGGGACGCTGGCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAAC
GCGTTTTGGCCTGATTTGAGGAGGGGGGCGGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGC
CCGCCTCCTCCCTCGGCCGGCCCTGGGGCCGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAG
GCCCCTAGGGTACAGCCCGATTTGGCCCCATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGC
TGCTGGTGGTGATCGTCGTCCTCGCCTTCAACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGG
GCCAGGTCCAGCGCACCGAAGTGGCCCGCGGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGA
TCGACCAGAAGGAGGCCGACTACGGCCGCCTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTA
AACTACAGAACAACATATCGTATCAGATGGCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAG
AAGACCAGCTTCAGGACTATAGGAAGAACAATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGG
AATTGAGAGCACAGCATGAAGAAAATATTAAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAA
ATGATGGAAAGGAATTGGATATAAACAATCAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAAC
CCTCAAGCAATCATATTCCACATGGGAAAGAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAA
AAGTTGATGATCTTCCCCCTGCACCAGTAACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAG
TATTTGACCCCTATTATTTCATCAAACATGTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAA
GCACACCGGAATTCTCCCTAGTTTTAGACTTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTC
CAGTCCTTTTCCAAGATGTCATTTATCAGGTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATG
AGATCATTCTTTTTACTGCTTCTAAGAAGGTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGC
TTTTCCGTGAACATTGTGTTTGTGTACAAGGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTG
ACAACTCACCACAAGCCTTTGCATATCAGCTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAA
AATTGATTCCATTCCTGGAGAAGCTTGTAGAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGC
CCCCAGATTAAGTACAAAGACTTGTCAAATCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACT
GTTGAAATTTTGCATTTTTGTACCCCGTCTTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTA
TCTCAGATCGAATACATATAGTAGGTAGGCTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACA
TCTGCAGTTTATAAAGAATTCTGTTTCTGCCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGG
ACTTTTATTTTCTCTCTGTTTGGTGCTCTAAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAG
TAAAAGTTGTTTTATTTTTCCTGTTAAGGTTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTT
AGTTGAGGCGCTTCATAGTTTTCTGGAGATAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTG
CACATTGTATATTTGTTTAAAAATATTCTCTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAA
TATTCTACTGTAGGTGAAATCTTTTCAAAAATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCAT
TGTGATGGCGTATATTCTCAAATGGTAATATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCAC
AAATCTTTGAGGAGAAAGTTTGGTCACCTGTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACA
GTGACTCAGTATTTTTAGTTATTTTGCATGGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCT
TGGTACCTAACAGTAGCTATGCATAATCCTGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCT
ATGCTATATGAAAATAGTCTTCAAGCCTTGGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTT
TCGGGAGGCTTTTTATGGAAGGTAGAATTTGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTT
TTGTGTAAAGGATGTCAAAGAACGGCACTTTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTA
AAGGTGGACAACTGATAATTGAGGAGTATGTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACAT
GCAGCTTCATTTTCAAATGAATCCTTAAAATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGT
TATGTCAATTTTCAGTGTATTAATGAAGATTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAG
CATATTGTGTCACTGAACTGTTTAAAAATCTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGG
CAGATTTTCTGCAAAAAAAAAACAAAAGCATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAG
GAAAAAAATACTACAGATTCATTTTAATGAGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCT
GTCTTTCTTGAAATAAAATGTACATACGTTACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTT
CCTTTTTATGCTCAAACAGCGAAACCCAAAACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGT
GCATTCTCAAAAGGGCTTTCCCATAATCTAAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAAC
TTTTTAAACTAATCATCTTTTATCAATGATAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGA
TACTTCCGTAAAGAAATAAACTAAGAAAATTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTA
TTTGAGTCATTTTAAATTTGTTAATACAAAATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTT
GTCTTCCCATTATCCTCTCTTTTCTTTATCTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGA
AATGTGCCCAGCCCCTTCAGCTCACACAGGAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGAC
ACAGCGAAAGTGACCTGTATACACATTACAACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGAC
ATTCTTTTAAATATTTGTATCATTGTTAGGATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATA
TCACCATATTTCTCCTTGTGTCCTAAGAGAATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTT
ACCCAATGGCTTTATCTGTTTCCCAAAATTTGTTTGGGATTTGTTGAAAGCATTGTGTAACTTCTATAAACGGCTATTTTCTTGTAACTG
TCAGTGAAATGAATGTGTACATTGTTTTCTTGTATTTCTCTGGGTTGTTTTTTGTTTTTTTTTCCAAGGGTTAACATAGAATGTTTTTTT
TAAAAAATTATCTTTGGCCAATGACTTTTTCATCTAGATCTTACTTTCATTCAACCTTCTAAAGAAGTTCGTTTCTCATTGTTTTGTTCT
GTCAACTTGCCTGAAAAACAGAGACTTCATCTCATCAATGAAGAAAGCATTTCATTATTCCTACAGATCTTTCCTGCGAGCACAGAATTC
TTCATAAGGACCAGATCTCTTCCATGTCTGTGTCAATCACATAAAGCTAAAATGTAAAGGACATTGAAGCCTTTATTTAATTGTACTAAT
ATGATGGTGTTATATACTACATCATTAGCTAGTTAAGGTTTTCTGACCTGACTTCTCTTTGTCTTCCTAGGTATTTATTTGTTATCTTTT
AATCTTGTGTATCTAAATTAACTTAGTTAATAGTTACCCACCGAATAACTATGCCAAGCAACTAGTAAAGAATGTTTATTTTATTTCCCC
TTATAGGGGAAGAGTGGACTGGGAACAAAAATGTATGGGCCAAAAGGCCTTAGGGTTGTCATTCATTGACTTTCTTATTCCTCTCATGAG
CTATAATTGAGTATAGTATTTTTTTAGTGCTGATGTCATTACTTCTCATGTCTTCCCCTGAGTTGAAAGCCTACGACAAACATGTATAAA
ATACATTTAAGAATTTTCAGAATATGAACCACAAAACTCAGTATCTTATATTTAAATGCTACTTAAGTTATTATTGGAATCCAAGTCTCA
CTAACTAGGGTACATTTTTATAAAATGTTTCTCTGTATCTTGAATTGAAATTACTTGCCCAGAGGCAAGAGTTCTGGGGATATAACATGA
TTTGAGATCTTTTTTAAAAAAGGGTGGGGCGGCGGGGGAGAGAGCGACAAGTTTATACTAGTTTATGCTTTTGATATTAGTATTTTAAGA
TACATCAGTTGATCCCGAAACCTGACCATTAGAATTACTCTGAGGAGCTTTTAAAATAGATTCCTGGAGCCTACCCCTGGAAAATTGTCT
CGCTGGATCTCGAGAGGGGCCTGAGAGTTCTGGCTTTTTTTTTTTGTTTGGTTGGTTTTGTTTTGTTTTGTTTTGTTTTTTCTTTAAAGC
TCTCCTGGTGATTCTAATAGCCAGTATTGGGTAATCAATGTTTTAGCTAAATGTGACACTGGTTTGAGAGTAGGCAACAAAATTAAAGTT
CACCAGACATCTCTTTGTGGTAGAGTTTTTTTTTTTTTAAACTGGGACCAGATTTCACAGAGCTTATTCAAGATACATGGAGGAATAATA
AAGAAGATTAAGGCTACTGCTCATTATCATTTTTGTCTTTCATATTTTTTAAGGGTTTGCATTTCTAGGACTTGGAATAGTTGACCATAT
ACATAGCTAAAGGACATGTCCCTGAATGAGACCATTATATATATTATCTGTAAAATATTTCACTATTTTTTTATTTTATAAATCTTTGTA
GAAATAAGCAATGAAATACTACTTTCATCTTTTGAAATGGGATTTTTCAAGGCAGTGTCCTTTTGGCATTAAGGTAGGGGGGAGTTAATA
TTCTCTCTGCCTTGTTTCCACGTGAATCAATATTAAAGTCATGGACATTTTAAAATCTCAATTTAATTTCTTCTTATTTACTATGCAGTA
TAGCCGTGAACAAGTAATGTAGATTTAGTTTTCTCATCTTCAAATGCCCTGATCACCCTACCTCACAGGGTTGTTGTGGGGATAAATAAA

>13166_13166_1_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000260327_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_2_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000396780_length(transcript)=4869nt_BP=1101nt
CCGTGAGGTGTTGGGTTTGGGGGACGCTGGCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAAC
GCGTTTTGGCCTGATTTGAGGAGGGGGGCGGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGC
CCGCCTCCTCCCTCGGCCGGCCCTGGGGCCGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAG
GCCCCTAGGGTACAGCCCGATTTGGCCCCATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGC
TGCTGGTGGTGATCGTCGTCCTCGCCTTCAACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGG
GCCAGGTCCAGCGCACCGAAGTGGCCCGCGGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGA
TCGACCAGAAGGAGGCCGACTACGGCCGCCTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTA
AACTACAGAACAACATATCGTATCAGATGGCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAG
AAGACCAGCTTCAGGACTATAGGAAGAACAATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGG
AATTGAGAGCACAGCATGAAGAAAATATTAAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAA
ATGATGGAAAGGAATTGGATATAAACAATCAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAAC
CCTCAAGCAATCATATTCCACATGGGAAAGAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAA
AAGTTGATGATCTTCCCCCTGCACCAGTAACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAG
TATTTGACCCCTATTATTTCATCAAACATGTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAA
GCACACCGGAATTCTCCCTAGTTTTAGACTTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTC
CAGTCCTTTTCCAAGATGTCATTTATCAGGTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATG
AGATCATTCTTTTTACTGCTTCTAAGAAGGTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGC
TTTTCCGTGAACATTGTGTTTGTGTACAAGGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTG
ACAACTCACCACAAGCCTTTGCATATCAGCTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAA
AATTGATTCCATTCCTGGAGAAGCTTGTAGAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGC
CCCCAGATTAAGTACAAAGACTTGTCAAATCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACT
GTTGAAATTTTGCATTTTTGTACCCCGTCTTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTA
TCTCAGATCGAATACATATAGTAGGTAGGCTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACA
TCTGCAGTTTATAAAGAATTCTGTTTCTGCCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGG
ACTTTTATTTTCTCTCTGTTTGGTGCTCTAAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAG
TAAAAGTTGTTTTATTTTTCCTGTTAAGGTTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTT
AGTTGAGGCGCTTCATAGTTTTCTGGAGATAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTG
CACATTGTATATTTGTTTAAAAATATTCTCTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAA
TATTCTACTGTAGGTGAAATCTTTTCAAAAATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCAT
TGTGATGGCGTATATTCTCAAATGGTAATATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCAC
AAATCTTTGAGGAGAAAGTTTGGTCACCTGTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACA
GTGACTCAGTATTTTTAGTTATTTTGCATGGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCT
TGGTACCTAACAGTAGCTATGCATAATCCTGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCT
ATGCTATATGAAAATAGTCTTCAAGCCTTGGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTT
TCGGGAGGCTTTTTATGGAAGGTAGAATTTGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTT
TTGTGTAAAGGATGTCAAAGAACGGCACTTTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTA
AAGGTGGACAACTGATAATTGAGGAGTATGTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACAT
GCAGCTTCATTTTCAAATGAATCCTTAAAATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGT
TATGTCAATTTTCAGTGTATTAATGAAGATTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAG
CATATTGTGTCACTGAACTGTTTAAAAATCTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGG
CAGATTTTCTGCAAAAAAAAAACAAAAGCATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAG
GAAAAAAATACTACAGATTCATTTTAATGAGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCT
GTCTTTCTTGAAATAAAATGTACATACGTTACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTT
CCTTTTTATGCTCAAACAGCGAAACCCAAAACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGT
GCATTCTCAAAAGGGCTTTCCCATAATCTAAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAAC
TTTTTAAACTAATCATCTTTTATCAATGATAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGA
TACTTCCGTAAAGAAATAAACTAAGAAAATTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTA
TTTGAGTCATTTTAAATTTGTTAATACAAAATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTT
GTCTTCCCATTATCCTCTCTTTTCTTTATCTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGA
AATGTGCCCAGCCCCTTCAGCTCACACAGGAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGAC
ACAGCGAAAGTGACCTGTATACACATTACAACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGAC
ATTCTTTTAAATATTTGTATCATTGTTAGGATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATA
TCACCATATTTCTCCTTGTGTCCTAAGAGAATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTT
ACCCAATGGCTTTATCTGTTTCCCAAAATTTGTTTGGGATTTGTTGAAAGCATTGTGTAACTTCTATAAACGGCTATTTTCTTGTAACTG

>13166_13166_2_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000396780_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_3_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000558373_length(transcript)=4869nt_BP=1101nt
CCGTGAGGTGTTGGGTTTGGGGGACGCTGGCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAAC
GCGTTTTGGCCTGATTTGAGGAGGGGGGCGGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGC
CCGCCTCCTCCCTCGGCCGGCCCTGGGGCCGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAG
GCCCCTAGGGTACAGCCCGATTTGGCCCCATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGC
TGCTGGTGGTGATCGTCGTCCTCGCCTTCAACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGG
GCCAGGTCCAGCGCACCGAAGTGGCCCGCGGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGA
TCGACCAGAAGGAGGCCGACTACGGCCGCCTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTA
AACTACAGAACAACATATCGTATCAGATGGCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAG
AAGACCAGCTTCAGGACTATAGGAAGAACAATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGG
AATTGAGAGCACAGCATGAAGAAAATATTAAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAA
ATGATGGAAAGGAATTGGATATAAACAATCAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAAC
CCTCAAGCAATCATATTCCACATGGGAAAGAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAA
AAGTTGATGATCTTCCCCCTGCACCAGTAACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAG
TATTTGACCCCTATTATTTCATCAAACATGTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAA
GCACACCGGAATTCTCCCTAGTTTTAGACTTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTC
CAGTCCTTTTCCAAGATGTCATTTATCAGGTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATG
AGATCATTCTTTTTACTGCTTCTAAGAAGGTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGC
TTTTCCGTGAACATTGTGTTTGTGTACAAGGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTG
ACAACTCACCACAAGCCTTTGCATATCAGCTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAA
AATTGATTCCATTCCTGGAGAAGCTTGTAGAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGC
CCCCAGATTAAGTACAAAGACTTGTCAAATCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACT
GTTGAAATTTTGCATTTTTGTACCCCGTCTTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTA
TCTCAGATCGAATACATATAGTAGGTAGGCTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACA
TCTGCAGTTTATAAAGAATTCTGTTTCTGCCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGG
ACTTTTATTTTCTCTCTGTTTGGTGCTCTAAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAG
TAAAAGTTGTTTTATTTTTCCTGTTAAGGTTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTT
AGTTGAGGCGCTTCATAGTTTTCTGGAGATAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTG
CACATTGTATATTTGTTTAAAAATATTCTCTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAA
TATTCTACTGTAGGTGAAATCTTTTCAAAAATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCAT
TGTGATGGCGTATATTCTCAAATGGTAATATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCAC
AAATCTTTGAGGAGAAAGTTTGGTCACCTGTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACA
GTGACTCAGTATTTTTAGTTATTTTGCATGGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCT
TGGTACCTAACAGTAGCTATGCATAATCCTGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCT
ATGCTATATGAAAATAGTCTTCAAGCCTTGGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTT
TCGGGAGGCTTTTTATGGAAGGTAGAATTTGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTT
TTGTGTAAAGGATGTCAAAGAACGGCACTTTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTA
AAGGTGGACAACTGATAATTGAGGAGTATGTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACAT
GCAGCTTCATTTTCAAATGAATCCTTAAAATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGT
TATGTCAATTTTCAGTGTATTAATGAAGATTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAG
CATATTGTGTCACTGAACTGTTTAAAAATCTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGG
CAGATTTTCTGCAAAAAAAAAACAAAAGCATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAG
GAAAAAAATACTACAGATTCATTTTAATGAGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCT
GTCTTTCTTGAAATAAAATGTACATACGTTACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTT
CCTTTTTATGCTCAAACAGCGAAACCCAAAACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGT
GCATTCTCAAAAGGGCTTTCCCATAATCTAAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAAC
TTTTTAAACTAATCATCTTTTATCAATGATAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGA
TACTTCCGTAAAGAAATAAACTAAGAAAATTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTA
TTTGAGTCATTTTAAATTTGTTAATACAAAATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTT
GTCTTCCCATTATCCTCTCTTTTCTTTATCTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGA
AATGTGCCCAGCCCCTTCAGCTCACACAGGAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGAC
ACAGCGAAAGTGACCTGTATACACATTACAACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGAC
ATTCTTTTAAATATTTGTATCATTGTTAGGATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATA
TCACCATATTTCTCCTTGTGTCCTAAGAGAATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTT
ACCCAATGGCTTTATCTGTTTCCCAAAATTTGTTTGGGATTTGTTGAAAGCATTGTGTAACTTCTATAAACGGCTATTTTCTTGTAACTG

>13166_13166_3_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000558373_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_4_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000558966_length(transcript)=2180nt_BP=1101nt
CCGTGAGGTGTTGGGTTTGGGGGACGCTGGCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAAC
GCGTTTTGGCCTGATTTGAGGAGGGGGGCGGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGC
CCGCCTCCTCCCTCGGCCGGCCCTGGGGCCGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAG
GCCCCTAGGGTACAGCCCGATTTGGCCCCATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGC
TGCTGGTGGTGATCGTCGTCCTCGCCTTCAACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGG
GCCAGGTCCAGCGCACCGAAGTGGCCCGCGGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGA
TCGACCAGAAGGAGGCCGACTACGGCCGCCTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTA
AACTACAGAACAACATATCGTATCAGATGGCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAG
AAGACCAGCTTCAGGACTATAGGAAGAACAATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGG
AATTGAGAGCACAGCATGAAGAAAATATTAAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAA
ATGATGGAAAGGAATTGGATATAAACAATCAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAAC
CCTCAAGCAATCATATTCCACATGGGAAAGAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAA
AAGTTGATGATCTTCCCCCTGCACCAGTAACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAG
TATTTGACCCCTATTATTTCATCAAACATGTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAA
GCACACCGGAATTCTCCCTAGTTTTAGACTTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTC
CAGTCCTTTTCCAAGATGTCATTTATCAGGTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATG
AGATCATTCTTTTTACTGCTTCTAAGAAGGTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGC
TTTTCCGTGAACATTGTGTTTGTGTACAAGGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTG
ACAACTCACCACAAGCCTTTGCATATCAGCTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAA
AATTGATTCCATTCCTGGAGAAGCTTGTAGAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGC
CCCCAGATTAAGTACAAAGACTTGTCAAATCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACT
GTTGAAATTTTGCATTTTTGTACCCCGTCTTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTA
TCTCAGATCGAATACATATAGTAGGTAGGCTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACA
TCTGCAGTTTATAAAGAATTCTGTTTCTGCCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGG

>13166_13166_4_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000299957_CTDSPL2_chr15_44788578_ENST00000558966_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_5_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000260327_length(transcript)=6646nt_BP=1072nt
GCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAACGCGTTTTGGCCTGATTTGAGGAGGGGGGC
GGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGCCCGCCTCCTCCCTCGGCCGGCCCTGGGGC
CGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAGGCCCCTAGGGTACAGCCCGATTTGGCCCC
ATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGCTGCTGGTGGTGATCGTCGTCCTCGCCTTC
AACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGGGCCAGGTCCAGCGCACCGAAGTGGCCCGC
GGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGATCGACCAGAAGGAGGCCGACTACGGCCGC
CTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTAAACTACAGAACAACATATCGTATCAGATG
GCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAGAAGACCAGCTTCAGGACTATAGGAAGAAC
AATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGGAATTGAGAGCACAGCATGAAGAAAATATT
AAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAAATGATGGAAAGGAATTGGATATAAACAAT
CAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAACCCTCAAGCAATCATATTCCACATGGGAAA
GAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAAAAGTTGATGATCTTCCCCCTGCACCAGTA
ACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAGTATTTGACCCCTATTATTTCATCAAACAT
GTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAAGCACACCGGAATTCTCCCTAGTTTTAGAC
TTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTCCAGTCCTTTTCCAAGATGTCATTTATCAG
GTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATGAGATCATTCTTTTTACTGCTTCTAAGAAG
GTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGCTTTTCCGTGAACATTGTGTTTGTGTACAA
GGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTGACAACTCACCACAAGCCTTTGCATATCAG
CTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAAAATTGATTCCATTCCTGGAGAAGCTTGTA
GAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGCCCCCAGATTAAGTACAAAGACTTGTCAAA
TCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACTGTTGAAATTTTGCATTTTTGTACCCCGTC
TTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTATCTCAGATCGAATACATATAGTAGGTAGG
CTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACATCTGCAGTTTATAAAGAATTCTGTTTCTG
CCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGGACTTTTATTTTCTCTCTGTTTGGTGCTCT
AAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAGTAAAAGTTGTTTTATTTTTCCTGTTAAGG
TTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTTAGTTGAGGCGCTTCATAGTTTTCTGGAGA
TAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTGCACATTGTATATTTGTTTAAAAATATTCT
CTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAATATTCTACTGTAGGTGAAATCTTTTCAAA
AATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCATTGTGATGGCGTATATTCTCAAATGGTAAT
ATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCACAAATCTTTGAGGAGAAAGTTTGGTCACCT
GTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACAGTGACTCAGTATTTTTAGTTATTTTGCAT
GGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCTTGGTACCTAACAGTAGCTATGCATAATCC
TGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCTATGCTATATGAAAATAGTCTTCAAGCCTT
GGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTTTCGGGAGGCTTTTTATGGAAGGTAGAATT
TGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTTTTGTGTAAAGGATGTCAAAGAACGGCACT
TTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTAAAGGTGGACAACTGATAATTGAGGAGTAT
GTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACATGCAGCTTCATTTTCAAATGAATCCTTAAA
ATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGTTATGTCAATTTTCAGTGTATTAATGAAGA
TTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAGCATATTGTGTCACTGAACTGTTTAAAAAT
CTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGGCAGATTTTCTGCAAAAAAAAAACAAAAGC
ATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAGGAAAAAAATACTACAGATTCATTTTAATG
AGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCTGTCTTTCTTGAAATAAAATGTACATACGT
TACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTTCCTTTTTATGCTCAAACAGCGAAACCCAA
AACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGTGCATTCTCAAAAGGGCTTTCCCATAATCT
AAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAACTTTTTAAACTAATCATCTTTTATCAATGA
TAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGATACTTCCGTAAAGAAATAAACTAAGAAAA
TTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTATTTGAGTCATTTTAAATTTGTTAATACAA
AATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTTGTCTTCCCATTATCCTCTCTTTTCTTTAT
CTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGAAATGTGCCCAGCCCCTTCAGCTCACACAG
GAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGACACAGCGAAAGTGACCTGTATACACATTAC
AACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGACATTCTTTTAAATATTTGTATCATTGTTAG
GATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATATCACCATATTTCTCCTTGTGTCCTAAGAG
AATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTTACCCAATGGCTTTATCTGTTTCCCAAAAT
TTGTTTGGGATTTGTTGAAAGCATTGTGTAACTTCTATAAACGGCTATTTTCTTGTAACTGTCAGTGAAATGAATGTGTACATTGTTTTC
TTGTATTTCTCTGGGTTGTTTTTTGTTTTTTTTTCCAAGGGTTAACATAGAATGTTTTTTTTAAAAAATTATCTTTGGCCAATGACTTTT
TCATCTAGATCTTACTTTCATTCAACCTTCTAAAGAAGTTCGTTTCTCATTGTTTTGTTCTGTCAACTTGCCTGAAAAACAGAGACTTCA
TCTCATCAATGAAGAAAGCATTTCATTATTCCTACAGATCTTTCCTGCGAGCACAGAATTCTTCATAAGGACCAGATCTCTTCCATGTCT
GTGTCAATCACATAAAGCTAAAATGTAAAGGACATTGAAGCCTTTATTTAATTGTACTAATATGATGGTGTTATATACTACATCATTAGC
TAGTTAAGGTTTTCTGACCTGACTTCTCTTTGTCTTCCTAGGTATTTATTTGTTATCTTTTAATCTTGTGTATCTAAATTAACTTAGTTA
ATAGTTACCCACCGAATAACTATGCCAAGCAACTAGTAAAGAATGTTTATTTTATTTCCCCTTATAGGGGAAGAGTGGACTGGGAACAAA
AATGTATGGGCCAAAAGGCCTTAGGGTTGTCATTCATTGACTTTCTTATTCCTCTCATGAGCTATAATTGAGTATAGTATTTTTTTAGTG
CTGATGTCATTACTTCTCATGTCTTCCCCTGAGTTGAAAGCCTACGACAAACATGTATAAAATACATTTAAGAATTTTCAGAATATGAAC
CACAAAACTCAGTATCTTATATTTAAATGCTACTTAAGTTATTATTGGAATCCAAGTCTCACTAACTAGGGTACATTTTTATAAAATGTT
TCTCTGTATCTTGAATTGAAATTACTTGCCCAGAGGCAAGAGTTCTGGGGATATAACATGATTTGAGATCTTTTTTAAAAAAGGGTGGGG
CGGCGGGGGAGAGAGCGACAAGTTTATACTAGTTTATGCTTTTGATATTAGTATTTTAAGATACATCAGTTGATCCCGAAACCTGACCAT
TAGAATTACTCTGAGGAGCTTTTAAAATAGATTCCTGGAGCCTACCCCTGGAAAATTGTCTCGCTGGATCTCGAGAGGGGCCTGAGAGTT
CTGGCTTTTTTTTTTTGTTTGGTTGGTTTTGTTTTGTTTTGTTTTGTTTTTTCTTTAAAGCTCTCCTGGTGATTCTAATAGCCAGTATTG
GGTAATCAATGTTTTAGCTAAATGTGACACTGGTTTGAGAGTAGGCAACAAAATTAAAGTTCACCAGACATCTCTTTGTGGTAGAGTTTT
TTTTTTTTTAAACTGGGACCAGATTTCACAGAGCTTATTCAAGATACATGGAGGAATAATAAAGAAGATTAAGGCTACTGCTCATTATCA
TTTTTGTCTTTCATATTTTTTAAGGGTTTGCATTTCTAGGACTTGGAATAGTTGACCATATACATAGCTAAAGGACATGTCCCTGAATGA
GACCATTATATATATTATCTGTAAAATATTTCACTATTTTTTTATTTTATAAATCTTTGTAGAAATAAGCAATGAAATACTACTTTCATC
TTTTGAAATGGGATTTTTCAAGGCAGTGTCCTTTTGGCATTAAGGTAGGGGGGAGTTAATATTCTCTCTGCCTTGTTTCCACGTGAATCA
ATATTAAAGTCATGGACATTTTAAAATCTCAATTTAATTTCTTCTTATTTACTATGCAGTATAGCCGTGAACAAGTAATGTAGATTTAGT

>13166_13166_5_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000260327_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_6_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000396780_length(transcript)=4840nt_BP=1072nt
GCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAACGCGTTTTGGCCTGATTTGAGGAGGGGGGC
GGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGCCCGCCTCCTCCCTCGGCCGGCCCTGGGGC
CGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAGGCCCCTAGGGTACAGCCCGATTTGGCCCC
ATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGCTGCTGGTGGTGATCGTCGTCCTCGCCTTC
AACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGGGCCAGGTCCAGCGCACCGAAGTGGCCCGC
GGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGATCGACCAGAAGGAGGCCGACTACGGCCGC
CTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTAAACTACAGAACAACATATCGTATCAGATG
GCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAGAAGACCAGCTTCAGGACTATAGGAAGAAC
AATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGGAATTGAGAGCACAGCATGAAGAAAATATT
AAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAAATGATGGAAAGGAATTGGATATAAACAAT
CAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAACCCTCAAGCAATCATATTCCACATGGGAAA
GAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAAAAGTTGATGATCTTCCCCCTGCACCAGTA
ACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAGTATTTGACCCCTATTATTTCATCAAACAT
GTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAAGCACACCGGAATTCTCCCTAGTTTTAGAC
TTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTCCAGTCCTTTTCCAAGATGTCATTTATCAG
GTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATGAGATCATTCTTTTTACTGCTTCTAAGAAG
GTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGCTTTTCCGTGAACATTGTGTTTGTGTACAA
GGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTGACAACTCACCACAAGCCTTTGCATATCAG
CTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAAAATTGATTCCATTCCTGGAGAAGCTTGTA
GAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGCCCCCAGATTAAGTACAAAGACTTGTCAAA
TCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACTGTTGAAATTTTGCATTTTTGTACCCCGTC
TTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTATCTCAGATCGAATACATATAGTAGGTAGG
CTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACATCTGCAGTTTATAAAGAATTCTGTTTCTG
CCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGGACTTTTATTTTCTCTCTGTTTGGTGCTCT
AAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAGTAAAAGTTGTTTTATTTTTCCTGTTAAGG
TTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTTAGTTGAGGCGCTTCATAGTTTTCTGGAGA
TAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTGCACATTGTATATTTGTTTAAAAATATTCT
CTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAATATTCTACTGTAGGTGAAATCTTTTCAAA
AATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCATTGTGATGGCGTATATTCTCAAATGGTAAT
ATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCACAAATCTTTGAGGAGAAAGTTTGGTCACCT
GTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACAGTGACTCAGTATTTTTAGTTATTTTGCAT
GGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCTTGGTACCTAACAGTAGCTATGCATAATCC
TGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCTATGCTATATGAAAATAGTCTTCAAGCCTT
GGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTTTCGGGAGGCTTTTTATGGAAGGTAGAATT
TGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTTTTGTGTAAAGGATGTCAAAGAACGGCACT
TTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTAAAGGTGGACAACTGATAATTGAGGAGTAT
GTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACATGCAGCTTCATTTTCAAATGAATCCTTAAA
ATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGTTATGTCAATTTTCAGTGTATTAATGAAGA
TTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAGCATATTGTGTCACTGAACTGTTTAAAAAT
CTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGGCAGATTTTCTGCAAAAAAAAAACAAAAGC
ATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAGGAAAAAAATACTACAGATTCATTTTAATG
AGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCTGTCTTTCTTGAAATAAAATGTACATACGT
TACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTTCCTTTTTATGCTCAAACAGCGAAACCCAA
AACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGTGCATTCTCAAAAGGGCTTTCCCATAATCT
AAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAACTTTTTAAACTAATCATCTTTTATCAATGA
TAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGATACTTCCGTAAAGAAATAAACTAAGAAAA
TTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTATTTGAGTCATTTTAAATTTGTTAATACAA
AATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTTGTCTTCCCATTATCCTCTCTTTTCTTTAT
CTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGAAATGTGCCCAGCCCCTTCAGCTCACACAG
GAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGACACAGCGAAAGTGACCTGTATACACATTAC
AACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGACATTCTTTTAAATATTTGTATCATTGTTAG
GATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATATCACCATATTTCTCCTTGTGTCCTAAGAG
AATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTTACCCAATGGCTTTATCTGTTTCCCAAAAT

>13166_13166_6_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000396780_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_7_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000558373_length(transcript)=4840nt_BP=1072nt
GCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAACGCGTTTTGGCCTGATTTGAGGAGGGGGGC
GGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGCCCGCCTCCTCCCTCGGCCGGCCCTGGGGC
CGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAGGCCCCTAGGGTACAGCCCGATTTGGCCCC
ATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGCTGCTGGTGGTGATCGTCGTCCTCGCCTTC
AACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGGGCCAGGTCCAGCGCACCGAAGTGGCCCGC
GGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGATCGACCAGAAGGAGGCCGACTACGGCCGC
CTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTAAACTACAGAACAACATATCGTATCAGATG
GCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAGAAGACCAGCTTCAGGACTATAGGAAGAAC
AATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGGAATTGAGAGCACAGCATGAAGAAAATATT
AAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAAATGATGGAAAGGAATTGGATATAAACAAT
CAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAACCCTCAAGCAATCATATTCCACATGGGAAA
GAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAAAAGTTGATGATCTTCCCCCTGCACCAGTA
ACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAGTATTTGACCCCTATTATTTCATCAAACAT
GTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAAGCACACCGGAATTCTCCCTAGTTTTAGAC
TTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTCCAGTCCTTTTCCAAGATGTCATTTATCAG
GTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATGAGATCATTCTTTTTACTGCTTCTAAGAAG
GTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGCTTTTCCGTGAACATTGTGTTTGTGTACAA
GGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTGACAACTCACCACAAGCCTTTGCATATCAG
CTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAAAATTGATTCCATTCCTGGAGAAGCTTGTA
GAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGCCCCCAGATTAAGTACAAAGACTTGTCAAA
TCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACTGTTGAAATTTTGCATTTTTGTACCCCGTC
TTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTATCTCAGATCGAATACATATAGTAGGTAGG
CTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACATCTGCAGTTTATAAAGAATTCTGTTTCTG
CCACCAGCAGTTTGACCTGTAGTCACACAGGATTTTATGATAATAACAGAGATGAAAATGGACTTTTATTTTCTCTCTGTTTGGTGCTCT
AAGTGGGTTTGTAGCCACTTTTCTGTTACTTTATGATTCTCATTTCAACAGGAATGGCCAGTAAAAGTTGTTTTATTTTTCCTGTTAAGG
TTTATAACCTTTTTACATTTTTGACCTGTATTAGATTAGAATTTCATTATGCATTCCTTTTAGTTGAGGCGCTTCATAGTTTTCTGGAGA
TAGTCAATTTTTAGTTTTTTATTATACATTTGAATGGCCGTTTTCCTGCTTTGTCTGCCTGCACATTGTATATTTGTTTAAAAATATTCT
CTACTTTTAGTCTATGTAAGTTTCATTTAGAAAGACATGCATTTATATTTTGTTTCTGTAATATTCTACTGTAGGTGAAATCTTTTCAAA
AATCAAGAGACTGGGTAGATAAGAATATATGAATGACTAATATACAAAAGATTTAAACCATTGTGATGGCGTATATTCTCAAATGGTAAT
ATCTTGCAATGGCACACAGATTTAATGGATAAAGGTATACCTCAGACTTCACTGTGCTCACAAATCTTTGAGGAGAAAGTTTGGTCACCT
GTTTGGCTTGATTTAGTTACTGCTGCCTTTGGTTTTCTCCAGGAATGAAGTATTCAGCACAGTGACTCAGTATTTTTAGTTATTTTGCAT
GGGCTGGTAGTACCTCTGTTATGCTCTCAGTTACAATCAATTTAAAACTGTATAACAGTCTTGGTACCTAACAGTAGCTATGCATAATCC
TGTGGCACAGTACACTCCCAAGCCACCAATGCAGTTAATATGCTCTCATAGTGGTTTTTCTATGCTATATGAAAATAGTCTTCAAGCCTT
GGTTCTCTAATGCAGCTACCACAAGAGGTTGATATTTTTATAGTGGCGTGTAATCTCCTTTTCGGGAGGCTTTTTATGGAAGGTAGAATT
TGTAAAAGTTCGTATGCTTTGCCTCTCAACTGCATTAACATGCCACAGGCTCAGACTGTTTTTGTGTAAAGGATGTCAAAGAACGGCACT
TTTTCTAAAGAGAAGTTTGATATTTTGTATGCTTGTTAAGAAAGTACAGTATTGGAAATTAAAGGTGGACAACTGATAATTGAGGAGTAT
GTCAATTAATTTTTTATGTATATTACCTGTTTACTTGTACAACTTACTGTACAAATTACATGCAGCTTCATTTTCAAATGAATCCTTAAA
ATAAGGAAATCTTTTTAGGAAAACATTTAATTTTTGTATTTTTGATTTTAAAGGCATGAGTTATGTCAATTTTCAGTGTATTAATGAAGA
TTTTAACTTTTCATCAGGTTGAGTGTTTTCTTACTATATTATCTGTTGTGTATGTAGTTAGCATATTGTGTCACTGAACTGTTTAAAAAT
CTAGCATGTAGAGCAAGCCTGTTTTGTGGAAAATCCTTATTCATTAAAAAAATAATCATGGCAGATTTTCTGCAAAAAAAAAACAAAAGC
ATTTGCAATTCAGAATACTGATTTTTTTAATTTTATTTAAAGAAAGGTATTTTGCTTGCAGGAAAAAAATACTACAGATTCATTTTAATG
AGAATCTTTGAAATGTATTTATCTTTAGGGCATCTGGGCATCTTTATGCTGTTTGTCTTCTGTCTTTCTTGAAATAAAATGTACATACGT
TACCTTTACATATGCTCTTGCTCAAAATTGTGAACCTAGTTACATTTCTCCCTGCTCCCTTCCTTTTTATGCTCAAACAGCGAAACCCAA
AACTTAAAAGATCTGAACTTTCAGCATGCATTCTGATTGCTGAAAGATTTCCTGATTTAGTGCATTCTCAAAAGGGCTTTCCCATAATCT
AAAGGGAAATGTAAGCACCTATACTCTTGTGCCTGTGGGCACTTCAATAATAAAAACCAACTTTTTAAACTAATCATCTTTTATCAATGA
TAAAGTTGTTTTCAGTCCCACACTAGGAGAGTTCCTTTAAGTCAGCTGATCAAGCATAAGATACTTCCGTAAAGAAATAAACTAAGAAAA
TTTTTTATGGCTTGAGAAAATTCCTTGAGGCCAAATTAATATATTTTTCTTTGTTATTTTATTTGAGTCATTTTAAATTTGTTAATACAA
AATTTAAGATAATTTACAGAGACAATTTATCCAGCTTCCTTCTACCTTAATACAATGTTTTGTCTTCCCATTATCCTCTCTTTTCTTTAT
CTGTTGGTAGATGTAAAAAACTTCCATTTAGTTAATCGGAGGTGTGTATTTTTTAAATTGAAATGTGCCCAGCCCCTTCAGCTCACACAG
GAAACATGAACTCTTAAAAAACTGACTAGTAAATGCAGGAGAGGTGGATACCTGATGAGACACAGCGAAAGTGACCTGTATACACATTAC
AACTCTGGAGTACATATTAAAGTCGTGCTATTTCCAGTGGTAAATGTCTGACTTTTAAGACATTCTTTTAAATATTTGTATCATTGTTAG
GATGTTTTAATCAGTTGTTTTTTAATTCCATGTAATATATGTAGCCCTCATCAGATTTATATCACCATATTTCTCCTTGTGTCCTAAGAG
AATTGATGACAATTCGTAACCATAAATTGTTTTATATTAGCTAGTATGTATATTTATTTTTACCCAATGGCTTTATCTGTTTCCCAAAAT

>13166_13166_7_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000558373_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------
>13166_13166_8_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000558966_length(transcript)=2151nt_BP=1072nt
GCAGCTGGGTTCTCCCGGTTCCCTTGGGCAGGTGCAGGGTCGGGTTCAAAGCCTCCGGAACGCGTTTTGGCCTGATTTGAGGAGGGGGGC
GGGGAGGGACCTGCGGCTTGCGGCCCCGCCCCCTTCTCCGGCTCGCAGCCGACCGGTAAGCCCGCCTCCTCCCTCGGCCGGCCCTGGGGC
CGTGTCCGCCGGGCAACTCCAGCCGAGGCCTGGGCTTCTGCCTGCAGGTGTCTGCGGCGAGGCCCCTAGGGTACAGCCCGATTTGGCCCC
ATGGTGGGTTTCGGGGCCAACCGGCGGGCTGGCCGCCTGCCCTCTCTCGTGCTGGTGGTGCTGCTGGTGGTGATCGTCGTCCTCGCCTTC
AACTACTGGAGCATCTCCTCCCGCCACGTCCTGCTTCAGGAGGAGGTGGCCGAGCTGCAGGGCCAGGTCCAGCGCACCGAAGTGGCCCGC
GGGCGGCTGGAAAAGCGCAATTCGGACCTCTTGCTGTTGGTGGACACGCACAAGAAACAGATCGACCAGAAGGAGGCCGACTACGGCCGC
CTCAGCAGCCGGCTGCAGGCCAGAGAGGGCCTCGGGAAGAGATGCGAGGATGACAAGGTTAAACTACAGAACAACATATCGTATCAGATG
GCAGACATACATCATTTAAAGGAGCAACTTGCTGAGCTTCGTCAGGAATTTCTTCGACAAGAAGACCAGCTTCAGGACTATAGGAAGAAC
AATACTTACCTTGTGAAGAGGTTAGAATATGAAAGTTTTCAGTGTGGACAGCAGATGAAGGAATTGAGAGCACAGCATGAAGAAAATATT
AAAAAGTTAGCAGACCAGTTTTTAGAGGAACAAAAGCAAGAGACCCAAAAGATTCAATCAAATGATGGAAAGGAATTGGATATAAACAAT
CAAGTAGTACCTAAAAATATTCCAAAAGTAGCTGAGAATGTTGCAGATAAGAATGAAGAACCCTCAAGCAATCATATTCCACATGGGAAA
GAACAAATCAAAAGAGGTGGTGATGCAGGGATGCCTGGAATAGAAGAGAATGACCTAGCAAAAGTTGATGATCTTCCCCCTGCACCAGTA
ACTCCAGATAGTGGTTATTCATCAGCCCACGCGGAGGCCACCTATGAAGAAGACTGGGAAGTATTTGACCCCTATTATTTCATCAAACAT
GTCCCGCCACTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCGTTGAAAACAAGAAGCACACCGGAATTCTCCCTAGTTTTAGAC
TTGGATGAAACACTAGTGCATTGTAGTCTAAATGAGCTAGAAGATGCAGCACTTACTTTTCCAGTCCTTTTCCAAGATGTCATTTATCAG
GTTTATGTGAGATTAAGACCATTTTTCAGGGAATTCCTGGAACGAATGTCTCAGATGTATGAGATCATTCTTTTTACTGCTTCTAAGAAG
GTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCGGCTTTTCCGTGAACATTGTGTTTGTGTACAA
GGAAACTATATAAAGGACTTAAATATTCTTGGAAGAGATCTTTCAAAAACTATAATAATTGACAACTCACCACAAGCCTTTGCATATCAG
CTTTCTAATGGAATCCCTATAGAAAGTTGGTTTATGGATAAAAATGACAATGAACTCCTAAAATTGATTCCATTCCTGGAGAAGCTTGTA
GAACTGAATGAAGATGTTCGACCACACATCAGAGACAGATTTCGCTTGCATGATTTGCTGCCCCCAGATTAAGTACAAAGACTTGTCAAA
TCACTGAAGGGGGAGAGAATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACTGTTGAAATTTTGCATTTTTGTACCCCGTC
TTGCTTTTCTTATCTTTGGTGCCCAATAATAATTAAGGGTTACAGAAAGAGACTTTATCTATCTCAGATCGAATACATATAGTAGGTAGG
CTAAAACAGAAGAGTCTTTAGAACTAGTGCAACTCCAGTGAAATTTTTTATGTACAGGACATCTGCAGTTTATAAAGAATTCTGTTTCTG

>13166_13166_8_CASC4-CTDSPL2_CASC4_chr15_44630515_ENST00000345795_CTDSPL2_chr15_44788578_ENST00000558966_length(amino acids)=503AA_BP=0
MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGR
LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPAPV
TPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQ
VYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CASC4-CTDSPL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CASC4-CTDSPL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CASC4-CTDSPL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCASC4C0001973Alcoholic Intoxication, Chronic1PSYGENET