Fusion Gene Studies
in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FKBP9-LANCL2 (FusionGDB2 ID:HG11328TG55915)

Fusion Gene Summary for FKBP9-LANCL2

check button Fusion gene summary
Fusion gene informationFusion gene name: FKBP9-LANCL2
Fusion gene ID: hg11328tg55915
HgeneTgene
Gene symbol

FKBP9

LANCL2

Gene ID

11328

55915

Gene nameFKBP prolyl isomerase 9LanC like 2
SynonymsFKBP60|FKBP63|PPIaseGPR69B|TASP
Cytomap('FKBP9')('LANCL2')

7p14.3

7p11.2

Type of geneprotein-codingprotein-coding
Descriptionpeptidyl-prolyl cis-trans isomerase FKBP963 kDa FK506-binding protein63 kDa FKBPFK506 binding protein 9, 63 kDaFK506-binding protein 9FKBP-63FKBP-9PPIase FKBP9rotamaselanC-like protein 2G protein-coupled receptor 69BLanC (bacterial lantibiotic synthetase component C)-like 2LanC lantibiotic synthetase component C-like 2testis-specific adriamycin sensitivity protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000242209, ENST00000490776, 
ENST00000538336, ENST00000538443, 
ENST00000489038, 
Fusion gene scores* DoF score7 X 7 X 4=19612 X 7 X 6=504
# samples 711
** MAII scorelog2(7/196*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/504*10)=-2.19592020997526
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FKBP9 [Title/Abstract] AND LANCL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFKBP9(33039872)-LANCL2(55466116), # samples:1
Anticipated loss of major functional domain due to fusion event.FKBP9-LANCL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FKBP9-LANCL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FKBP9-LANCL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FKBP9-LANCL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLANCL2

GO:0009789

positive regulation of abscisic acid-activated signaling pathway

19667068

TgeneLANCL2

GO:0045892

negative regulation of transcription, DNA-templated

12566319


check buttonFusion gene breakpoints across FKBP9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LANCL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-19-2624-01AFKBP9chr7

33039872

+LANCL2chr7

55466116

+


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Fusion Gene ORF analysis for FKBP9-LANCL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000242209ENST00000486376FKBP9chr7

33039872

+LANCL2chr7

55466116

+
5CDS-3UTRENST00000490776ENST00000486376FKBP9chr7

33039872

+LANCL2chr7

55466116

+
5CDS-3UTRENST00000538336ENST00000486376FKBP9chr7

33039872

+LANCL2chr7

55466116

+
5CDS-3UTRENST00000538443ENST00000486376FKBP9chr7

33039872

+LANCL2chr7

55466116

+
In-frameENST00000242209ENST00000254770FKBP9chr7

33039872

+LANCL2chr7

55466116

+
In-frameENST00000490776ENST00000254770FKBP9chr7

33039872

+LANCL2chr7

55466116

+
In-frameENST00000538336ENST00000254770FKBP9chr7

33039872

+LANCL2chr7

55466116

+
In-frameENST00000538443ENST00000254770FKBP9chr7

33039872

+LANCL2chr7

55466116

+
intron-3CDSENST00000489038ENST00000254770FKBP9chr7

33039872

+LANCL2chr7

55466116

+
intron-3UTRENST00000489038ENST00000486376FKBP9chr7

33039872

+LANCL2chr7

55466116

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000242209FKBP9chr733039872+ENST00000254770LANCL2chr755466116+499415411692571800
ENST00000538336FKBP9chr733039872+ENST00000254770LANCL2chr755466116+511716641332694853
ENST00000538443FKBP9chr733039872+ENST00000254770LANCL2chr755466116+477913263652356663
ENST00000490776FKBP9chr733039872+ENST00000254770LANCL2chr755466116+4207754781784568

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000242209ENST00000254770FKBP9chr733039872+LANCL2chr755466116+0.0001790520.999821
ENST00000538336ENST00000254770FKBP9chr733039872+LANCL2chr755466116+0.0001217260.9998783
ENST00000538443ENST00000254770FKBP9chr733039872+LANCL2chr755466116+0.0002814140.9997186
ENST00000490776ENST00000254770FKBP9chr733039872+LANCL2chr755466116+0.0001970840.9998029

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Fusion Genomic Features for FKBP9-LANCL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FKBP9chr733039872+LANCL2chr755466115+2.67E-091
FKBP9chr733039872+LANCL2chr755466115+2.67E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FKBP9-LANCL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:33039872/chr7:55466116)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810166_254457571.0DomainPPIase FKBP-type 2
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810278_365457571.0DomainPPIase FKBP-type 3
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+81054_142457571.0DomainPPIase FKBP-type 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810501_513457571.0Calcium binding1
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810546_557457571.0Calcium binding2
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810389_477457571.0DomainPPIase FKBP-type 4
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810488_523457571.0DomainEF-hand 1
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810533_568457571.0DomainEF-hand 2
HgeneFKBP9chr7:33039872chr7:55466116ENST00000242209+810567_570457571.0MotifPrevents secretion from ER


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Fusion Gene Sequence for FKBP9-LANCL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>30541_30541_1_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000242209_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4994nt_BP=1541nt
CCCTGGAGCTGCGGCCGGGAGGGCGGGCGGCCGGGGAGACGGGGTGGCGGCTGCAGCCCGGGTAGGGCCAGGAGACCCGGTCCACGTTTG
CAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGCCCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCTCGCCGCCCCGATGGCGTTCCG
GGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCTGCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGTGGCGGGCCTGGGCTCCGACGC
GGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGAGTGCCCGCGCACCGTGCGCAGCGGCGACTTCGTGCGCTACCACTACGTGGGGAC
GTTCCCCGACGGCCAGAAGTTCGACTCCAGCTATGACAGAGACTCCACTTTCAATGTGTTTGTGGGAAAAGGACAGCTGATCACAGGGAT
GGACCAGGCTCTTGTTGGGATGTGCGTAAACGAGAGACGTTTCGTGAAGATTCCCCCAAAGCTTGCCTACGGAAATGAAGGAGTTTCTGG
TGTGATCCCCCCCAATTCAGTGCTTCATTTTGATGTACTTCTGATGGATATTTGGAATTCTGAAGACCAGGTTCAGATTCACACCTATTT
CAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGTCTGATTTTGTGAGGTACCACTACAACGGGACGTTCCTGGACGGAACTCTGTTTGA
TTCGAGTCACAATCGCATGAAAACATATGACACGTATGTGGGAATTGGCTGGCTGATTCCTGGAATGGATAAAGGGCTGCTGGGGATGTG
TGTGGGTGAGAAGCGCATCATCACCATTCCTCCTTTTCTGGCCTATGGAGAGGATGGAGATGGGAAAGACATTCCCGGTCAGGCATCTCT
GGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGAGAACAAGGTAGTACCTGAAAACTGTGAGCGGAT
AAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCACCCTCTTTGATTCCAGCTACTCTCGGAACCGCAC
GTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACTTGGTGTTTGCATTGGAGAAAAGCGAAGGATTGT
GGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGCTGTGCTGGTGTTTGACATCCATGTGATCGACTT
CCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTCAGTGCTGAGTAAGAAGGGAGATTACCTCAAATA
TCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGGCAAAACTTACAATATTGTTCTGGGATCTGGGCA
AGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGACAGTGATCATTCCGCCTCACCTGGGCTATGGGGA
AGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCAAACCTACCTGCTCCGATCCCTGGATTACGTAAA
AAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGGCCCCCTGGCTGTTGGAGCTGTGATTTATCACAA
ACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAGATCGGTTGTCTGCCAAGAATCAGACCTTCCTGA
TGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGAGATAGGTCCAGGCACCGTGTGTGAGTCAGCTAT
TAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAGAAAAACGGAGCGCTGCCCGCTGTTGTACCAGTG
GCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTTAATGCAGCCGGCAGCAAAAGTGGACCAAGAAAC
CTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATCTGGGAATTACCCATCATCATTAAGCAATGAAAC
AGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCAGGCGTACAAGGTCTTTAAGGAGGAGAAGTACTT
GAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGGCTACGGGATATGCCATGGGACTGCTGGCAACGG
CTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGCTTGCAAGTTTGCAGAGTGGTGTCTAGATTACGG
AGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGGCGCTATTCACTTTCTCTCTGATGTCCTGGGACC
AGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGTGCAAAAAGACAACTAAAATACCCATTTGGACCA
AAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGAAGCAGACACCGTCACAGGCCCCTCTGGTTAGAC
TAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATATAAAATATGACTTCTTCACATACAGATTCTCTGT
AGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGAAGGCCCTTCTATTCCTGAGGGCTCAGAGCTGAC
CATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTTTCTTCCATATTGACAAATGAGGGAACAGGTGGT
GTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGTCAGCCTTTTCTGTGGCACCTTCCAGATGAGAAT
GAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGGGAGTGCACAGCTGAACGCTTCCC
GTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCTCTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAG
GTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCAAAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCA
CACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATATGTTACTAAAACAGGCTCCACCTCAGTTTATCAA
CATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGATTAACAGAAAGACACTCAACTGGACTCATGTCC
CTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATGAATGCATTTCCTATTTTTTGTCTACTTTTGGGT
GATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACAACATTATGGTATTTGTGTGACTTTTATTTGAAA
AAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTCAGTTTTTAGAAGGGTTTCTGTCATCATGGAAGA
GGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGACAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTC
TGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAGAAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCC
TTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTTCTAAACGATGCCTGGAGAGTCTGTTTGCTGCAG
ACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAATAGAAATCATCCTGATCCTATTTTACCTGGCCT
CCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGATGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTT
GCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCCCACCCACCACATCAAAACATAACACATCACAGC
ACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCCAGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGA
CGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGGATGCGGGTGTCTCCCCAGGTGAGTCCATCCACA
CACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTGTGGAATAAAGGAGGAGATTTTATTTACAGATTT
TTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGGTGCTGTTCCGTGGTTCTGCATTAACCCCTGCCT
CATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAACGGGACTTACTTCACAGGACAGAGGATTGACAGA
AGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAGATTTGTATTCACAATTGTGTTCTCTAAAATGTG
TCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAATTTGAAGTCCACAAAAAGTGTTTGAGGTTCTTT

>30541_30541_1_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000242209_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=800AA_BP=457
MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQL
ITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDG
TLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPEN
CERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIH
VIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHL
GYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQES
DLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKV
DQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGT

--------------------------------------------------------------
>30541_30541_2_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000490776_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4207nt_BP=754nt
AAAGGCCAGTGGAAGGAGCTCAGGCTTGGCGGCATCTGGTTTGCTTGTCTGGGCCTACTCCTTTGCATGATATAACAAATGGCAGGGAAA
GACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGAGAACAAGGTA
GTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCACCCTCTTTGAT
TCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACTTGGTGTTTGC
ATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGCTGTGCTGGTG
TTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTCAGTGCTGAGT
AAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGGCAAAACTTAC
AATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGACAGTGATCATT
CCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCAAACCTACCTG
CTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGGCCCCCTGGCT
GTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAGATCGGTTGTC
TGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGAGATAGGTCCA
GGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAGAAAAACGGAG
CGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTTAATGCAGCCG
GCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATCTGGGAATTAC
CCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCAGGCGTACAAG
GTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGGCTACGGGATA
TGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGCTTGCAAGTTT
GCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGGCGCTATTCAC
TTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGTGCAAAAAGAC
AACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGAAGCAGACACC
GTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATATAAAATATGAC
TTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGAAGGCCCTTCT
ATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTTTCTTCCATAT
TGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGTCAGCCTTTTC
TGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGG
GAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCTCTGTCAGGGC
CCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCAAAGGGAGCTT
TCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATATGTTACTAAAA
CAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGATTAACAGAAA
GACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATGAATGCATTTC
CTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACAACATTATGGT
ATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTCAGTTTTTAGA
AGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGACAAGAGGCCT
CTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAGAAAAAAGAAT
GTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTTCTAAACGATG
CCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAATAGAAATCAT
CCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGATGCTGTCGTC
AATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCCCACCCACCAC
ATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCCAGCACGGTGC
TCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGGATGCGGGTGT
CTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTGTGGAATAAAG
GAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGGTGCTGTTCCG
TGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAACGGGACTTACT
TCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAGATTTGTATTC
ACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAATTTGAAGTCC

>30541_30541_2_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000490776_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=568AA_BP=225
MAGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGL
LGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNL
GKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDA
GPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREE
RKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGVIHMLM
QAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMA

--------------------------------------------------------------
>30541_30541_3_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538336_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=5117nt_BP=1664nt
AGACGGGGTGGCGGCTGCAGCCCGGGTAGGGCCAGGAGACCCGGTCCACGTTTGCAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGC
CCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCTCGCCGCCCCGATGGCGTTCCGGGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCT
GCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGTGGCGGGCCTGGGCTCCGACGCGGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGA
GTGCCCGCGCACCGTGCGCAGCGGCGACTTCGTGCGCTACCACTACGTGGGGACGTTCCCCGACGGCCAGAAGTTCGACTCCAGGTACTG
GGATACAGCGGAGGATAAAGCTGACAAAAGTCCCTGCCCTCAAGTCAGGGTTGGGGTGAACACAAGCCCGTCCTGCAGACTTAAGCAGAA
AGGAGTGGGAATTTATTGGAAGGATCTCCAATTCCTTGTGAGGGTCCAGAATCATGGACTGAGCTATGACAGAGACTCCACTTTCAATGT
GTTTGTGGGAAAAGGACAGCTGATCACAGGGATGGACCAGGCTCTTGTTGGGATGTGCGTAAACGAGAGACGTTTCGTGAAGATTCCCCC
AAAGCTTGCCTACGGAAATGAAGGAGTTTCTGGTGTGATCCCCCCCAATTCAGTGCTTCATTTTGATGTACTTCTGATGGATATTTGGAA
TTCTGAAGACCAGGTTCAGATTCACACCTATTTCAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGTCTGATTTTGTGAGGTACCACTA
CAACGGGACGTTCCTGGACGGAACTCTGTTTGATTCGAGTCACAATCGCATGAAAACATATGACACGTATGTGGGAATTGGCTGGCTGAT
TCCTGGAATGGATAAAGGGCTGCTGGGGATGTGTGTGGGTGAGAAGCGCATCATCACCATTCCTCCTTTTCTGGCCTATGGAGAGGATGG
AGATGGGAAAGACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACCCCAAGGACAGCATTTCCATTGA
GAACAAGGTAGTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACAATGGCACGCTTCTGGATGGCAC
CCTCTTTGATTCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTCCTGGGATGGATGAAGGTCTACT
TGGTGTTTGCATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAAGAGGGAATATCCCCGGCTCGGC
TGTGCTGGTGTTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCCACTACAAACCCCCTGACTGCTC
AGTGCTGAGTAAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGCTGGACTCCACGTGGAATTTAGG
CAAAACTTACAATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGATGTGCGTTGGCGAGAAACGGAC
AGTGATCATTCCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGTTGTACCGGGTCACATGTGACCA
AACCTACCTGCTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCACCTTCCTCTGTGGGGATGCTGG
CCCCCTGGCTGTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCACAAAACTTTTGCAGCTCCAGAG
ATCGGTTGTCTGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATGCCTTACTGTACCTGAACACAGA
GATAGGTCCAGGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTAAGACTTTGTCAAGGGAAGAAAG
AAAAACGGAGCGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCATGGCTGGAATTTACTATATGTT
AATGCAGCCGGCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATGTGCGCCACAAAAAATTCCGATC
TGGGAATTACCCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGGGGGTCATCCACATGCTCATGCA
GGCGTACAAGGTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGCAGCGAGGTTTGCTGCGGAAGGG
CTACGGGATATGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGGATAAGAAGTACCTCTACCGAGC
TTGCAAGTTTGCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATTCGCTCTTTGAAGGCATGGCTGG
CGCTATTCACTTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACTCTTCGAAGAGGGATTAAAAGGT
GCAAAAAGACAACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAACAACTGGGAATCCTGAAAGAGA
AGCAGACACCGTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTTCTAACAGCACCCTCATCAATAT
AAAATATGACTTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCAGGTGTAAGCTGTTTTAAATGGA
AGGCCCTTCTATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGTATAAAATGTATAAAGTGGGGTT
TCTTCCATATTGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTCTATCCTAGTGATAATACATTGT
CAGCCTTTTCTGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAGCAGTTCTGCAGGGGCGTGCTGG
GGTGGTTTGGGAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGAAGCCTCAGAGTGCATTGCAGCT
CTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTTGTTGGGGAGACTTCTGGACCCA
AAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTCCAGAACATTTACCCAGGTATAT
GTTACTAAAACAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACAGTTCCAGATGGGTTATTGCAGA
TTAACAGAAAGACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTTATCAAAATCTAAATTTGGAATG
AATGCATTTCCTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAGAAACATAATGTTCTAACCAACA
ACATTATGGTATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCATTAATTCTATCACATAGATTTC
AGTTTTTAGAAGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAGCTAAGGCTTGTGTCATGAAAGA
CAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGTGTCCACACCTCTCAGAAAAGAG
AAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACCCGAAATGTGTGACATTCAGCTT
CTAAACGATGCCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATGTTAGATTGATGACTTCTGTGAA
TAGAAATCATCCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAGCAGCCCACACCTGCAGGCAGGA
TGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAAATAACATTGTTCCCATCCTCCC
CACCCACCACATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGGGAAGCCAGTAGGCAACACAGCC
AGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGAGCAGCCACAAAGGTGGCCTAGG
ATGCGGGTGTCTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACACTGAGGGAAAGATTAAAATCTG
TGGAATAAAGGAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTTATCCACTAGATGTCATCAGAGG
TGCTGTTCCGTGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGGTCCCTCCAGGCAAAGGAGAAAC
GGGACTTACTTCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCAGTACATCTCATTCATTTCTTAG
ATTTGTATTCACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCATTTTAAAATCTGAAGGAAAGAA

>30541_30541_3_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538336_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=853AA_BP=510
MAFRGWRPPPPPLLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFDSRYWDTAEDKADKSPCPQ
VRVGVNTSPSCRLKQKGVGIYWKDLQFLVRVQNHGLSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIP
PNSVLHFDVLLMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGE
KRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDT
YIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYN
ASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTL
RNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEV
VNAIIESGKTLSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRL
VHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHG

--------------------------------------------------------------
>30541_30541_4_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538443_LANCL2_chr7_55466116_ENST00000254770_length(transcript)=4779nt_BP=1326nt
AGGAGACCCGGTCCACGTTTGCAAACGCAGCCGAACGCCCAGGCCGACCCGTGCCGCCCGAGCGCCGCGCTGCGTCCGCGCCACTCTTCT
CGCCGCCCCGATGGCGTTCCGGGGCTGGAGGCCCCCGCCGCCACCGCTGCTCCTGCTGCTGCTCTGGGTGACCGGGCAGGCAGCGCCCGT
GGCGGGCCTGGGCTCCGACGCGGAGCTGCAGATCGAGCGGCGCTTCGTGCCCGACGAGTGCCCGCGCACCGTGCGCAGCGGCGACTTCGT
GCGCTACCACTACGTGGGGACGTTCCCCGACGGCCAGAAGTTCGACTCCAGCTGGTGTGATCCCCCCCAATTCAGTGCTTCATTTTGATG
TACTTCTGATGGATATTTGGAATTCTGAAGACCAGGTTCAGATTCACACCTATTTCAAGCCCCCGAGTTGCCCTCGGACCATCCAGGTGT
CTGATTTTGTGAGGTACCACTACAACGGGACGTTCCTGGACGGAACTCTGTTTGATTCGAGTCACAATCGCATGAAAACATATGACACGT
ATGTGGGAATTGGCTGGCTGATTCCTGGAATGGATAAAGGGCTGCTGGGGATGTGTGTGGGTGAGAAGCGCATCATCACCATTCCTCCTT
TTCTGGCCTATGGAGAGGATGGAGATGGGAAAGACATTCCCGGTCAGGCATCTCTGGTGTTTGATGTTGCATTATTGGACCTCCATAACC
CCAAGGACAGCATTTCCATTGAGAACAAGGTAGTACCTGAAAACTGTGAGCGGATAAGTCAAAGTGGGGACTTTCTCAGGTATCATTACA
ATGGCACGCTTCTGGATGGCACCCTCTTTGATTCCAGCTACTCTCGGAACCGCACGTTTGACACGTACATTGGGCAGGGCTACGTGATTC
CTGGGATGGATGAAGGTCTACTTGGTGTTTGCATTGGAGAAAAGCGAAGGATTGTGGTCCCGCCTCACCTGGGGTATGGAGAGGAAGGAA
GAGGGAATATCCCCGGCTCGGCTGTGCTGGTGTTTGACATCCATGTGATCGACTTCCACAACCCTTCGGACTCCATCAGCATCACCTCCC
ACTACAAACCCCCTGACTGCTCAGTGCTGAGTAAGAAGGGAGATTACCTCAAATATCACTACAATGCCTCACTTCTGGATGGGACCCTGC
TGGACTCCACGTGGAATTTAGGCAAAACTTACAATATTGTTCTGGGATCTGGGCAAGTTGTGTTGGGGATGGACATGGGTCTCAGAGAGA
TGTGCGTTGGCGAGAAACGGACAGTGATCATTCCGCCTCACCTGGGCTATGGGGAAGCTGGCGTGGGCATAGCCCTTTTGTACCTGCAGT
TGTACCGGGTCACATGTGACCAAACCTACCTGCTCCGATCCCTGGATTACGTAAAAAGAACACTTCGGAATCTGAATGGCCGCAGGGTCA
CCTTCCTCTGTGGGGATGCTGGCCCCCTGGCTGTTGGAGCTGTGATTTATCACAAACTCAGAAGTGACTGTGAGTCCCAGGAATGTGTCA
CAAAACTTTTGCAGCTCCAGAGATCGGTTGTCTGCCAAGAATCAGACCTTCCTGATGAGCTGCTTTATGGACGGGCAGGTTATCTGTATG
CCTTACTGTACCTGAACACAGAGATAGGTCCAGGCACCGTGTGTGAGTCAGCTATTAAAGAGGTAGTCAATGCTATTATTGAATCGGGTA
AGACTTTGTCAAGGGAAGAAAGAAAAACGGAGCGCTGCCCGCTGTTGTACCAGTGGCACCGGAAGCAGTACGTTGGAGCAGCCCATGGCA
TGGCTGGAATTTACTATATGTTAATGCAGCCGGCAGCAAAAGTGGACCAAGAAACCTTGACAGAAATGGTGAAACCCAGTATTGATTATG
TGCGCCACAAAAAATTCCGATCTGGGAATTACCCATCATCATTAAGCAATGAAACAGACCGGCTGGTGCACTGGTGCCACGGCGCCCCGG
GGGTCATCCACATGCTCATGCAGGCGTACAAGGTCTTTAAGGAGGAGAAGTACTTGAAAGAGGCCATGGAGTGTAGCGATGTGATTTGGC
AGCGAGGTTTGCTGCGGAAGGGCTACGGGATATGCCATGGGACTGCTGGCAACGGCTATTCCTTCCTGTCCCTTTACCGTCTCACGCAGG
ATAAGAAGTACCTCTACCGAGCTTGCAAGTTTGCAGAGTGGTGTCTAGATTACGGAGCACACGGGTGCCGCATTCCTGACAGACCCTATT
CGCTCTTTGAAGGCATGGCTGGCGCTATTCACTTTCTCTCTGATGTCCTGGGACCAGAGACATCACGGTTTCCAGCATTTGAACTTGACT
CTTCGAAGAGGGATTAAAAGGTGCAAAAAGACAACTAAAATACCCATTTGGACCAAAAGCCACCAGATTGCTTAGTGCCTGACACAGAAA
CAACTGGGAATCCTGAAAGAGAAGCAGACACCGTCACAGGCCCCTCTGGTTAGACTAGCATGAGTGACCGAAGCCATCCATCAACATTTT
CTAACAGCACCCTCATCAATATAAAATATGACTTCTTCACATACAGATTCTCTGTAGTGTTTGCATGTTTCTTGGTGTTTGTTGTCTCCA
GGTGTAAGCTGTTTTAAATGGAAGGCCCTTCTATTCCTGAGGGCTCAGAGCTGACCATGCATGAATGTATGGCAGTGTCCACTTTTCTGT
ATAAAATGTATAAAGTGGGGTTTCTTCCATATTGACAAATGAGGGAACAGGTGGTGTCTATCTTGTATATCAGAAAGATTATCTAGGGTC
TATCCTAGTGATAATACATTGTCAGCCTTTTCTGTGGCACCTTCCAGATGAGAATGAGGGAGCGACCACTCCAAGGACGGACAGGACCAG
CAGTTCTGCAGGGGCGTGCTGGGGTGGTTTGGGAGTGCACAGCTGAACGCTTCCCGTTTGGATTTTACACTCACCTTCGTGTTTTAAAGA
AGCCTCAGAGTGCATTGCAGCTCTGTCAGGGCCCCATTCCCAGCAGAGGCTTCAGGTGCTTTGTGTAGAGTCCAGGGCAGCTGGAGCTTT
GTTGGGGAGACTTCTGGACCCAAAGGGAGCTTTCCCAAGAAGCCTTTGATGGCCACACTGTAGGCAGCAGTGACTAAGCACTGGCAGTTC
CAGAACATTTACCCAGGTATATGTTACTAAAACAGGCTCCACCTCAGTTTATCAACATTATAAGTTACTGTTCTAAGAAAAGTAAATACA
GTTCCAGATGGGTTATTGCAGATTAACAGAAAGACACTCAACTGGACTCATGTCCCTGCAATTAAACTTACTTCAACCTTTTGGAAAGTT
ATCAAAATCTAAATTTGGAATGAATGCATTTCCTATTTTTTGTCTACTTTTGGGTGATAAAAAGTACTAGCCCTTATTTATAGATATGAG
AAACATAATGTTCTAACCAACAACATTATGGTATTTGTGTGACTTTTATTTGAAAAAATGTGAGCAGTAATTTGGGTTAGCCTACCTTCA
TTAATTCTATCACATAGATTTCAGTTTTTAGAAGGGTTTCTGTCATCATGGAAGAGGTGGTCTGGGACTAGGTACTTCTCGTCTTGTGAG
CTAAGGCTTGTGTCATGAAAGACAAGAGGCCTCTCTTAACAGCCCAGTCCTTGTCTGCAGGGGGAGGCCTGAGCATTTCCCAGCCCCAGT
GTCCACACCTCTCAGAAAAGAGAAAAAAGAATGTCAGTTTAGGAGAAAAGCTTCCTTTTTACTTGTGTGGTTATGTGTGGGGCTGGCACC
CGAAATGTGTGACATTCAGCTTCTAAACGATGCCTGGAGAGTCTGTTTGCTGCAGACACCCTTGCTCCTGAGTCATTATTTTCTTTCATG
TTAGATTGATGACTTCTGTGAATAGAAATCATCCTGATCCTATTTTACCTGGCCTCCAGGGCCTGTTGATGGGCTTTGCAGGCAGTCCAG
CAGCCCACACCTGCAGGCAGGATGCTGTCGTCAATGAGCTGAGGGTAGCTGCTTTGCTGAAGACCTCACACGATGTCCAATCTCATCCAA
ATAACATTGTTCCCATCCTCCCCACCCACCACATCAAAACATAACACATCACAGCACTCAGTAGAGGTCCTGCCTCCCCATTTCTCAAGG
GAAGCCAGTAGGCAACACAGCCAGCACGGTGCTCTCCAGGGCAGCCCCTCTCAGACGAGGAGGCAGCGGGTGCAGCCAGGTGTCTGCAGA
GCAGCCACAAAGGTGGCCTAGGATGCGGGTGTCTCCCCAGGTGAGTCCATCCACACACGTTTGAAAAACACTATTAGTCTTTCTAACACA
CTGAGGGAAAGATTAAAATCTGTGGAATAAAGGAGGAGATTTTATTTACAGATTTTTTTAAAAGCCACCTGGGTTGACACCTTCCTACTT
ATCCACTAGATGTCATCAGAGGTGCTGTTCCGTGGTTCTGCATTAACCCCTGCCTCATGTCTGTAACATGTGACAGTAATTCCAGCTCGG
TCCCTCCAGGCAAAGGAGAAACGGGACTTACTTCACAGGACAGAGGATTGACAGAAGTCAGTTTAAGATAAGTGTTTGAATCAGATTTCA
GTACATCTCATTCATTTCTTAGATTTGTATTCACAATTGTGTTCTCTAAAATGTGTCTAAATTTTAAAAATATGTACATGCATAATGTCA
TTTTAAAATCTGAAGGAAAGAATTTGAAGTCCACAAAAAGTGTTTGAGGTTCTTTGGTTTTGTTAGTAAAAGCCAGTTCTGTGGTGATGA

>30541_30541_4_FKBP9-LANCL2_FKBP9_chr7_33039872_ENST00000538443_LANCL2_chr7_55466116_ENST00000254770_length(amino acids)=663AA_BP=320
MMDIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIPPFL
AYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPG
MDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLD
STWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVGIALLYLQLYRVTCDQTYLLRSLDYVKRTLRNLNGRRVTF
LCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKT
LSREERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLVHWCHGAPGV
IHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FKBP9-LANCL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneLANCL2chr7:33039872chr7:55466116ENST00000254770192_15107.33333333333333451.0inositol phospholipids


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FKBP9-LANCL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FKBP9-LANCL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource