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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP1-COPS7B (FusionGDB2 ID:HG116987TG64708)

Fusion Gene Summary for AGAP1-COPS7B

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1-COPS7B
Fusion gene ID: hg116987tg64708
HgeneTgene
Gene symbol

AGAP1

COPS7B

Gene ID

116987

64708

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1COP9 signalosome subunit 7B
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2CSN7B|SGN7b
Cytomap('AGAP1')('COPS7B')

2q37.2

2q37.1

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2COP9 signalosome complex subunit 7bCOP9 constitutive photomorphogenic homolog subunit 7BJAB1-containing signalosome subunit 7bsignalosome subunit 7b
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304032, ENST00000336665, 
ENST00000409457, ENST00000409538, 
ENST00000428334, 
Fusion gene scores* DoF score49 X 18 X 17=149944 X 5 X 3=60
# samples 485
** MAII scorelog2(48/14994*10)=-4.96520709119934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGAP1 [Title/Abstract] AND COPS7B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236659132)-COPS7B(232672196), # samples:1
Anticipated loss of major functional domain due to fusion event.AGAP1-COPS7B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-COPS7B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-COPS7B seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCOPS7B

GO:0000338

protein deneddylation

19141280


check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across COPS7B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-A8EQAGAP1chr2

236659132

+COPS7Bchr2

232672196

+


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Fusion Gene ORF analysis for AGAP1-COPS7B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000304032ENST00000350033AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000304032ENST00000410017AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000304032ENST00000410024AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000336665ENST00000350033AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000336665ENST00000410017AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000336665ENST00000410024AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409457ENST00000350033AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409457ENST00000410017AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409457ENST00000410024AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409538ENST00000350033AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409538ENST00000410017AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000409538ENST00000410024AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000428334ENST00000350033AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000428334ENST00000410017AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
Frame-shiftENST00000428334ENST00000410024AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000304032ENST00000373608AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000304032ENST00000409091AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000304032ENST00000409295AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000336665ENST00000373608AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000336665ENST00000409091AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000336665ENST00000409295AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409457ENST00000373608AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409457ENST00000409091AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409457ENST00000409295AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409538ENST00000373608AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409538ENST00000409091AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000409538ENST00000409295AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000428334ENST00000373608AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000428334ENST00000409091AGAP1chr2

236659132

+COPS7Bchr2

232672196

+
In-frameENST00000428334ENST00000409295AGAP1chr2

236659132

+COPS7Bchr2

232672196

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336665AGAP1chr2236659132+ENST00000409295COPS7Bchr2232672196+158212531278202358
ENST00000336665AGAP1chr2236659132+ENST00000409091COPS7Bchr2232672196+146212531278202358
ENST00000336665AGAP1chr2236659132+ENST00000373608COPS7Bchr2232672196+302012531278202358
ENST00000304032AGAP1chr2236659132+ENST00000409295COPS7Bchr2232672196+158212531278202358
ENST00000304032AGAP1chr2236659132+ENST00000409091COPS7Bchr2232672196+146212531278202358
ENST00000304032AGAP1chr2236659132+ENST00000373608COPS7Bchr2232672196+302012531278202358
ENST00000409538AGAP1chr2236659132+ENST00000409295COPS7Bchr2232672196+22931964198913658
ENST00000409538AGAP1chr2236659132+ENST00000409091COPS7Bchr2232672196+21731964198913658
ENST00000409538AGAP1chr2236659132+ENST00000373608COPS7Bchr2232672196+37311964198913658
ENST00000428334AGAP1chr2236659132+ENST00000409295COPS7Bchr2232672196+5402112128487
ENST00000428334AGAP1chr2236659132+ENST00000409091COPS7Bchr2232672196+4202112128487
ENST00000428334AGAP1chr2236659132+ENST00000373608COPS7Bchr2232672196+1978211843448131
ENST00000409457AGAP1chr2236659132+ENST00000409295COPS7Bchr2232672196+160012711296220358
ENST00000409457AGAP1chr2236659132+ENST00000409091COPS7Bchr2232672196+148012711296220358
ENST00000409457AGAP1chr2236659132+ENST00000373608COPS7Bchr2232672196+303812711296220358

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336665ENST00000409295AGAP1chr2236659132+COPS7Bchr2232672196+0.0030428620.9969572
ENST00000336665ENST00000409091AGAP1chr2236659132+COPS7Bchr2232672196+0.0021117480.99788827
ENST00000336665ENST00000373608AGAP1chr2236659132+COPS7Bchr2232672196+0.0010184270.99898154
ENST00000304032ENST00000409295AGAP1chr2236659132+COPS7Bchr2232672196+0.0030428620.9969572
ENST00000304032ENST00000409091AGAP1chr2236659132+COPS7Bchr2232672196+0.0021117480.99788827
ENST00000304032ENST00000373608AGAP1chr2236659132+COPS7Bchr2232672196+0.0010184270.99898154
ENST00000409538ENST00000409295AGAP1chr2236659132+COPS7Bchr2232672196+0.0195259270.9804741
ENST00000409538ENST00000409091AGAP1chr2236659132+COPS7Bchr2232672196+0.0215188470.9784812
ENST00000409538ENST00000373608AGAP1chr2236659132+COPS7Bchr2232672196+0.0050419130.9949581
ENST00000428334ENST00000409295AGAP1chr2236659132+COPS7Bchr2232672196+0.064866480.9351336
ENST00000428334ENST00000409091AGAP1chr2236659132+COPS7Bchr2232672196+0.0460477470.95395225
ENST00000428334ENST00000373608AGAP1chr2236659132+COPS7Bchr2232672196+0.493740320.5062597
ENST00000409457ENST00000409295AGAP1chr2236659132+COPS7Bchr2232672196+0.0031165860.99688333
ENST00000409457ENST00000409091AGAP1chr2236659132+COPS7Bchr2232672196+0.0021028210.99789715
ENST00000409457ENST00000373608AGAP1chr2236659132+COPS7Bchr2232672196+0.0010754790.99892455

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Fusion Genomic Features for AGAP1-COPS7B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
AGAP1chr2236659132+COPS7Bchr2232672196+2.70E-091
AGAP1chr2236659132+COPS7Bchr2232672196+2.70E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for AGAP1-COPS7B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:236659132/chr2:232672196)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618122_126224858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618178_181224858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+61878_85224858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617122_126224805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617178_181224805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+61778_85224805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610122_126224406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610178_181224406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+61078_85224406.0Nucleotide bindingGTP
TgeneCOPS7Bchr2:236659132chr2:232672196ENST0000040909135188_237105158.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618346_588224858.0DomainPH
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618609_729224858.0DomainArf-GAP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617346_588224805.0DomainPH
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617609_729224805.0DomainArf-GAP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610346_588224406.0DomainPH
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610609_729224406.0DomainArf-GAP
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+61866_276224858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+61766_276224805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+61066_276224406.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618768_797224858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618801_830224858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617768_797224805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617801_830224805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610768_797224406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610801_830224406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236659132chr2:232672196ENST00000304032+618624_647224858.0Zinc fingerC4-type
HgeneAGAP1chr2:236659132chr2:232672196ENST00000336665+617624_647224805.0Zinc fingerC4-type
HgeneAGAP1chr2:236659132chr2:232672196ENST00000409457+610624_647224406.0Zinc fingerC4-type
TgeneCOPS7Bchr2:236659132chr2:232672196ENST0000035003357188_237212265.0Coiled coilOntology_term=ECO:0000255
TgeneCOPS7Bchr2:236659132chr2:232672196ENST0000037360868188_237229274.0Coiled coilOntology_term=ECO:0000255
TgeneCOPS7Bchr2:236659132chr2:232672196ENST0000041002457188_237212265.0Coiled coilOntology_term=ECO:0000255
TgeneCOPS7Bchr2:236659132chr2:232672196ENST00000350033572_159212265.0DomainPCI
TgeneCOPS7Bchr2:236659132chr2:232672196ENST00000373608682_159229274.0DomainPCI
TgeneCOPS7Bchr2:236659132chr2:232672196ENST00000409091352_159105158.0DomainPCI
TgeneCOPS7Bchr2:236659132chr2:232672196ENST00000410024572_159212265.0DomainPCI


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Fusion Gene Sequence for AGAP1-COPS7B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2764_2764_1_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000373608_length(transcript)=3020nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCA
GCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCACCCACTCCCTCCTTCCCCAGTTGTTCCCTTCAGACTCA
GGGGCTCCACCAATGCCATCCCAAAACAGGGTCAGACACTGCCCAGCTTCCCTCCAGGAGGTTCTTGTCTCTGTGTAAGGGCTTGTCTCC
CTCCCAGTTTTTCTTTTGCTCCACGTCATTTTGTCAGGCTGGTTATAAGCCGGAGGCAGCTTTAACCAGCCCCCAGGGATGATTGTGAAG
GAGGCCCCTCCCCTTGTGAGGAGGGGGCACTCCTCTCCAGCCCCTGGTACCACAGTCCTCACGATGGTGCAGTGATTTCTAGCCAGGCGT
CAAGATGCGCTGCTTTCCCTCTCCTGCCTCATCCCTTGTTGGCAGCTCCAGTTCAGGCCGTGGAGGGACGTGATGCTGGGCTGTGTTTAC
TAAACCCACGGGTTTTCAGCCTCTTAAGCCCAGCTCCGATCTCCAATTAGTTGAGAGCGCTGGGTTGACTAACCTCTGGTATCTGAGCAC
AGACAGAGGGTGCTGTGGGTCTGCTGGGTGGCAGAAATGGTTCCTTCCGGCTTGGCGTTCTCTCCTGGCCACTCTTCCTGCTGCCTCTGA
CTACTCAGCCTTGTTTTCGGTGTGTAGGCCCCAGCTGCCCACTGGAACTGCCGGCTAATGCTTGCTCTCCCAAGATCTTTAACTCCTCCT
GGCTGCACCTGGGTAGGGATGGTGGCATCGATGCCCCTCTGTCTGCTGAAGGACCTGTTGCTGCTTCTGTCTTTTCACCCCTCCTTGGCT
GATGACCCAGAGCCCTCTGATGATGGCATTCTCCTGGCAAGAGAAAAAGACTTAACTAGACTTCTGAACTTGAACAGTTTCAGGTTATAT
TTTAATTTTTTTTTTTTTGTACAGGTTCTGATTCTAATACATTTCAACATGCTTTTGTCCCCCCTCGTGTCAATATTTGTTATAGACTAA
TCGCCGGGGATTTTTCACCTGGTTGGAGGGTGGGGGTGGGGTGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTT
TGTAGGTCCTGGACTGATTAAAGTTCATTGAGGAAAAAGCACATTTTACAACAAAAAAATAAAAGTGTAGATTTAATGTATGTGACTGGG
GTTTGGGGTTGCATACCTGGTGGATCTTGAGGGGCTGGGATTAGGGTGGTTCAGGAAAATGTGATGCTGTTTCCCCATGTTTAGCCATGG
TCAAAAAATGGATTTCTCCTTTTTCTAAAATGTCCAGCAACTGCCTACTGTTGATCAAATGTTGAAGTATTCTTGTTTCCCTTTTAAGCC
AATCCATGTGCCCACATAACATTATGCCCAAGTGGAGAGTTCACTTTAATTTCCAAAGTATGTTTCATGCAGCCCCCTGTCAGCTGCTCT
GTGGAAAAGGGGTTCTGTTATGAAATAAATGTTGCACTCCCTGCATCCCA

>2764_2764_1_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000373608_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_2_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000409091_length(transcript)=1462nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGG

>2764_2764_2_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000409091_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_3_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000409295_length(transcript)=1582nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCA
GCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA

>2764_2764_3_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000304032_COPS7B_chr2_232672196_ENST00000409295_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_4_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000373608_length(transcript)=3020nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCA
GCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCACCCACTCCCTCCTTCCCCAGTTGTTCCCTTCAGACTCA
GGGGCTCCACCAATGCCATCCCAAAACAGGGTCAGACACTGCCCAGCTTCCCTCCAGGAGGTTCTTGTCTCTGTGTAAGGGCTTGTCTCC
CTCCCAGTTTTTCTTTTGCTCCACGTCATTTTGTCAGGCTGGTTATAAGCCGGAGGCAGCTTTAACCAGCCCCCAGGGATGATTGTGAAG
GAGGCCCCTCCCCTTGTGAGGAGGGGGCACTCCTCTCCAGCCCCTGGTACCACAGTCCTCACGATGGTGCAGTGATTTCTAGCCAGGCGT
CAAGATGCGCTGCTTTCCCTCTCCTGCCTCATCCCTTGTTGGCAGCTCCAGTTCAGGCCGTGGAGGGACGTGATGCTGGGCTGTGTTTAC
TAAACCCACGGGTTTTCAGCCTCTTAAGCCCAGCTCCGATCTCCAATTAGTTGAGAGCGCTGGGTTGACTAACCTCTGGTATCTGAGCAC
AGACAGAGGGTGCTGTGGGTCTGCTGGGTGGCAGAAATGGTTCCTTCCGGCTTGGCGTTCTCTCCTGGCCACTCTTCCTGCTGCCTCTGA
CTACTCAGCCTTGTTTTCGGTGTGTAGGCCCCAGCTGCCCACTGGAACTGCCGGCTAATGCTTGCTCTCCCAAGATCTTTAACTCCTCCT
GGCTGCACCTGGGTAGGGATGGTGGCATCGATGCCCCTCTGTCTGCTGAAGGACCTGTTGCTGCTTCTGTCTTTTCACCCCTCCTTGGCT
GATGACCCAGAGCCCTCTGATGATGGCATTCTCCTGGCAAGAGAAAAAGACTTAACTAGACTTCTGAACTTGAACAGTTTCAGGTTATAT
TTTAATTTTTTTTTTTTTGTACAGGTTCTGATTCTAATACATTTCAACATGCTTTTGTCCCCCCTCGTGTCAATATTTGTTATAGACTAA
TCGCCGGGGATTTTTCACCTGGTTGGAGGGTGGGGGTGGGGTGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTT
TGTAGGTCCTGGACTGATTAAAGTTCATTGAGGAAAAAGCACATTTTACAACAAAAAAATAAAAGTGTAGATTTAATGTATGTGACTGGG
GTTTGGGGTTGCATACCTGGTGGATCTTGAGGGGCTGGGATTAGGGTGGTTCAGGAAAATGTGATGCTGTTTCCCCATGTTTAGCCATGG
TCAAAAAATGGATTTCTCCTTTTTCTAAAATGTCCAGCAACTGCCTACTGTTGATCAAATGTTGAAGTATTCTTGTTTCCCTTTTAAGCC
AATCCATGTGCCCACATAACATTATGCCCAAGTGGAGAGTTCACTTTAATTTCCAAAGTATGTTTCATGCAGCCCCCTGTCAGCTGCTCT
GTGGAAAAGGGGTTCTGTTATGAAATAAATGTTGCACTCCCTGCATCCCA

>2764_2764_4_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000373608_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_5_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000409091_length(transcript)=1462nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGG

>2764_2764_5_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000409091_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_6_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000409295_length(transcript)=1582nt_BP=1253nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGT
GGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTT
CAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGT
GGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAA
CACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAA
GCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCA
ACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTG
AGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCA
GGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCA
GCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA

>2764_2764_6_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000336665_COPS7B_chr2_232672196_ENST00000409295_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_7_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000373608_length(transcript)=3038nt_BP=1271nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGA
GCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGC
GCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCG
AATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGA
TGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGT
CTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGG
AGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGG
GGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGAC
CTGCCCGTCCCCTCACCAGCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCACCCACTCCCTCCTTCCCCAG
TTGTTCCCTTCAGACTCAGGGGCTCCACCAATGCCATCCCAAAACAGGGTCAGACACTGCCCAGCTTCCCTCCAGGAGGTTCTTGTCTCT
GTGTAAGGGCTTGTCTCCCTCCCAGTTTTTCTTTTGCTCCACGTCATTTTGTCAGGCTGGTTATAAGCCGGAGGCAGCTTTAACCAGCCC
CCAGGGATGATTGTGAAGGAGGCCCCTCCCCTTGTGAGGAGGGGGCACTCCTCTCCAGCCCCTGGTACCACAGTCCTCACGATGGTGCAG
TGATTTCTAGCCAGGCGTCAAGATGCGCTGCTTTCCCTCTCCTGCCTCATCCCTTGTTGGCAGCTCCAGTTCAGGCCGTGGAGGGACGTG
ATGCTGGGCTGTGTTTACTAAACCCACGGGTTTTCAGCCTCTTAAGCCCAGCTCCGATCTCCAATTAGTTGAGAGCGCTGGGTTGACTAA
CCTCTGGTATCTGAGCACAGACAGAGGGTGCTGTGGGTCTGCTGGGTGGCAGAAATGGTTCCTTCCGGCTTGGCGTTCTCTCCTGGCCAC
TCTTCCTGCTGCCTCTGACTACTCAGCCTTGTTTTCGGTGTGTAGGCCCCAGCTGCCCACTGGAACTGCCGGCTAATGCTTGCTCTCCCA
AGATCTTTAACTCCTCCTGGCTGCACCTGGGTAGGGATGGTGGCATCGATGCCCCTCTGTCTGCTGAAGGACCTGTTGCTGCTTCTGTCT
TTTCACCCCTCCTTGGCTGATGACCCAGAGCCCTCTGATGATGGCATTCTCCTGGCAAGAGAAAAAGACTTAACTAGACTTCTGAACTTG
AACAGTTTCAGGTTATATTTTAATTTTTTTTTTTTTGTACAGGTTCTGATTCTAATACATTTCAACATGCTTTTGTCCCCCCTCGTGTCA
ATATTTGTTATAGACTAATCGCCGGGGATTTTTCACCTGGTTGGAGGGTGGGGGTGGGGTGGGGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTGTGTGTGTGTGTGTTTGTAGGTCCTGGACTGATTAAAGTTCATTGAGGAAAAAGCACATTTTACAACAAAAAAATAAAAGTGTAGAT
TTAATGTATGTGACTGGGGTTTGGGGTTGCATACCTGGTGGATCTTGAGGGGCTGGGATTAGGGTGGTTCAGGAAAATGTGATGCTGTTT
CCCCATGTTTAGCCATGGTCAAAAAATGGATTTCTCCTTTTTCTAAAATGTCCAGCAACTGCCTACTGTTGATCAAATGTTGAAGTATTC
TTGTTTCCCTTTTAAGCCAATCCATGTGCCCACATAACATTATGCCCAAGTGGAGAGTTCACTTTAATTTCCAAAGTATGTTTCATGCAG
CCCCCTGTCAGCTGCTCTGTGGAAAAGGGGTTCTGTTATGAAATAAATGTTGCACTCCCTGCATCCCA

>2764_2764_7_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000373608_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_8_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000409091_length(transcript)=1480nt_BP=1271nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGA
GCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGC
GCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCG
AATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGA
TGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGT
CTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGG
AGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGG
GGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGG

>2764_2764_8_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000409091_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_9_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000409295_length(transcript)=1600nt_BP=1271nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGA
GCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTC
TCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGC
GCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCG
AATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGA
TGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGT
CTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGG
AGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGG
GGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGAC
CTGCCCGTCCCCTCACCAGCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA

>2764_2764_9_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409457_COPS7B_chr2_232672196_ENST00000409295_length(amino acids)=358AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIF
DGDDVLPDLVLQHRLLHALQQLVDGVDVGVDRLEALDLGPDGSRVGQLLLVVHGAGAAPGAARPPPPPPRAPGPAGRRARGAAAPGEPGP
PAAGGGGARRKARAEQARGWPAGSVHGRDARPASERAPASRVSGPPGGSAPPWSAPRRVRPAPKEACSGDFLSRSRLPALGAAPRSSH

--------------------------------------------------------------
>2764_2764_10_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000373608_length(transcript)=3731nt_BP=1964nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC
AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG
GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC
CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC
GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC
GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG
CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA
GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT
GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA
AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT
GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA
CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG
GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG
CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT
GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA
GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT
TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA
CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGA
AGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGC
AGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGT
CAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCAGCGCCTCCC
CACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCACCCACTCCCTCCTTCCCCAGTTGTTCCCTTCAGACTCAGGGGCTCCA
CCAATGCCATCCCAAAACAGGGTCAGACACTGCCCAGCTTCCCTCCAGGAGGTTCTTGTCTCTGTGTAAGGGCTTGTCTCCCTCCCAGTT
TTTCTTTTGCTCCACGTCATTTTGTCAGGCTGGTTATAAGCCGGAGGCAGCTTTAACCAGCCCCCAGGGATGATTGTGAAGGAGGCCCCT
CCCCTTGTGAGGAGGGGGCACTCCTCTCCAGCCCCTGGTACCACAGTCCTCACGATGGTGCAGTGATTTCTAGCCAGGCGTCAAGATGCG
CTGCTTTCCCTCTCCTGCCTCATCCCTTGTTGGCAGCTCCAGTTCAGGCCGTGGAGGGACGTGATGCTGGGCTGTGTTTACTAAACCCAC
GGGTTTTCAGCCTCTTAAGCCCAGCTCCGATCTCCAATTAGTTGAGAGCGCTGGGTTGACTAACCTCTGGTATCTGAGCACAGACAGAGG
GTGCTGTGGGTCTGCTGGGTGGCAGAAATGGTTCCTTCCGGCTTGGCGTTCTCTCCTGGCCACTCTTCCTGCTGCCTCTGACTACTCAGC
CTTGTTTTCGGTGTGTAGGCCCCAGCTGCCCACTGGAACTGCCGGCTAATGCTTGCTCTCCCAAGATCTTTAACTCCTCCTGGCTGCACC
TGGGTAGGGATGGTGGCATCGATGCCCCTCTGTCTGCTGAAGGACCTGTTGCTGCTTCTGTCTTTTCACCCCTCCTTGGCTGATGACCCA
GAGCCCTCTGATGATGGCATTCTCCTGGCAAGAGAAAAAGACTTAACTAGACTTCTGAACTTGAACAGTTTCAGGTTATATTTTAATTTT
TTTTTTTTTGTACAGGTTCTGATTCTAATACATTTCAACATGCTTTTGTCCCCCCTCGTGTCAATATTTGTTATAGACTAATCGCCGGGG
ATTTTTCACCTGGTTGGAGGGTGGGGGTGGGGTGGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTAGGTCC
TGGACTGATTAAAGTTCATTGAGGAAAAAGCACATTTTACAACAAAAAAATAAAAGTGTAGATTTAATGTATGTGACTGGGGTTTGGGGT
TGCATACCTGGTGGATCTTGAGGGGCTGGGATTAGGGTGGTTCAGGAAAATGTGATGCTGTTTCCCCATGTTTAGCCATGGTCAAAAAAT
GGATTTCTCCTTTTTCTAAAATGTCCAGCAACTGCCTACTGTTGATCAAATGTTGAAGTATTCTTGTTTCCCTTTTAAGCCAATCCATGT
GCCCACATAACATTATGCCCAAGTGGAGAGTTCACTTTAATTTCCAAAGTATGTTTCATGCAGCCCCCTGTCAGCTGCTCTGTGGAAAAG
GGGTTCTGTTATGAAATAAATGTTGCACTCCCTGCATCCCA

>2764_2764_10_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000373608_length(amino acids)=658AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIS
ARGAVDALGAGRVRFGRGPPQAEVAAWPRGSAPWRGPAARAPVPAREDAAEEAQQPVLRGRAGPGRRPRALQPLQVAVVQRAVLALTAFP
TLQVRERVVLAEHLAHVQGVALLRGGLRGGRGLQGGPGRGLVARRPGQAPGAAVAPSAAQCPALRRLRPAPVPEAQAPPQGRGPGPLHVG
AAGRGRAASLLLGRGAAGQVRGFQAACARPEPPQFQLPGAAGAEGAEIPSARPGTLRFLGALRLLGLLLKPPGRVRGARGPGPPNRAWVR
AAGARRGQLLLPDHGHGDAVDSLSGGRPARHRVRGWRRGLATAVQQVHVARALGPRRIQRARGPGGRRAKRGGQAGRECGPRPPLTARAA
LRLRGRRPWHPPARAPRRPSAGVRARGAEPWAGGAKRGGRSGARALSPAGAAAVRRAQGRRRRPRLHCLRRGARAHPPAPAAQLGGSAAS
ATPWAPGRADSCTGCGRRVAGGGRRAAV

--------------------------------------------------------------
>2764_2764_11_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000409091_length(transcript)=2173nt_BP=1964nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC
AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG
GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC
CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC
GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC
GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG
CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA
GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT
GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA
AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT
GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA
CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG
GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG
CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT
GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA
GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT
TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA
CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGA
AGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGC
AGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGT
CAGGTGGGGAGGG

>2764_2764_11_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000409091_length(amino acids)=658AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIS
ARGAVDALGAGRVRFGRGPPQAEVAAWPRGSAPWRGPAARAPVPAREDAAEEAQQPVLRGRAGPGRRPRALQPLQVAVVQRAVLALTAFP
TLQVRERVVLAEHLAHVQGVALLRGGLRGGRGLQGGPGRGLVARRPGQAPGAAVAPSAAQCPALRRLRPAPVPEAQAPPQGRGPGPLHVG
AAGRGRAASLLLGRGAAGQVRGFQAACARPEPPQFQLPGAAGAEGAEIPSARPGTLRFLGALRLLGLLLKPPGRVRGARGPGPPNRAWVR
AAGARRGQLLLPDHGHGDAVDSLSGGRPARHRVRGWRRGLATAVQQVHVARALGPRRIQRARGPGGRRAKRGGQAGRECGPRPPLTARAA
LRLRGRRPWHPPARAPRRPSAGVRARGAEPWAGGAKRGGRSGARALSPAGAAAVRRAQGRRRRPRLHCLRRGARAHPPAPAAQLGGSAAS
ATPWAPGRADSCTGCGRRVAGGGRRAAV

--------------------------------------------------------------
>2764_2764_12_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000409295_length(transcript)=2293nt_BP=1964nt
GCGCGTTTCCATTTTAAACCGCCGCCCGCCGCCCGCCACCCGCCACCCTTCGGCCGCAGCCGGTGCAGCTGTCCGCGCGTCCCGGAGCCC
AGGGAGTGGCGGAGGCTGCGGAACCGCCGAGCTGTGCAGCCGGAGCGGGAGGATGCGCACGGGCCCCGCGTCGTAGACAATGAAGCCGCG
GGCGCCGCCGCCTGCCCTGGGCCCTGCGCACCGCGGCCGCACCTGCCGGCGAGAGCGCTCTAGCGCCTGACCGGCCGCCTCGCTTGGCCC
CGCCGGCCCATGGCTCGGCGCCCCGGGCCCGGACCCCGGCACTCGGGCGGCGCGGCGCACGGGCCGGCGGGTGCCAGGGGCGCCGTCCCC
GCAGCCTGAGTGCGGCCCTCGCGGTCAGCGGGGGGCGTGGGCCACACTCCCGGCCCGCCTGCCCTCCCCGCTTGGCCCGGCGCCCTCCCG
GCCCGCGGGCTCGCTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGC
GGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTGGCCGCGCCGGG
CTCCGGCGGCCCGGACCCACGCCCGGTTCGGCGGCCCCGGCCCGCGCGCTCCCCGGACGCGCCCGGGAGGCTTGAGGAGGAGGCCGAGGA
GGCGGAGGGCGCCGAGGAACCGGAGGGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACT
GGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGC
GTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCA
AGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCT
GGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGA
CCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGG
GGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCC
ACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGG
CTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTT
GGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGA
GATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGT
TATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGA
GATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAA
CGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGA
AGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGAGCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGC
AGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAGCCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGT
CAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCTACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCAGCGCCTCCC
CACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA

>2764_2764_12_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000409538_COPS7B_chr2_232672196_ENST00000409295_length(amino acids)=658AA_BP=
MSVFLMLVTVLEDPLHIQPVCSTRLVVRAPFQVVGELPRPGVIDDPRVSRTYGILGSHQNQRNLARVPIVGHSTVVVVNGLETYFILQAE
DKYNSVHPHGKLRLRGAPFISDQQQIALSINDNLFLEPATFRRLLLDICARQVPVHQGRLAAGQVTHNSHFELRDRSTQRPFLAVHEGIS
ARGAVDALGAGRVRFGRGPPQAEVAAWPRGSAPWRGPAARAPVPAREDAAEEAQQPVLRGRAGPGRRPRALQPLQVAVVQRAVLALTAFP
TLQVRERVVLAEHLAHVQGVALLRGGLRGGRGLQGGPGRGLVARRPGQAPGAAVAPSAAQCPALRRLRPAPVPEAQAPPQGRGPGPLHVG
AAGRGRAASLLLGRGAAGQVRGFQAACARPEPPQFQLPGAAGAEGAEIPSARPGTLRFLGALRLLGLLLKPPGRVRGARGPGPPNRAWVR
AAGARRGQLLLPDHGHGDAVDSLSGGRPARHRVRGWRRGLATAVQQVHVARALGPRRIQRARGPGGRRAKRGGQAGRECGPRPPLTARAA
LRLRGRRPWHPPARAPRRPSAGVRARGAEPWAGGAKRGGRSGARALSPAGAAAVRRAQGRRRRPRLHCLRRGARAHPPAPAAQLGGSAAS
ATPWAPGRADSCTGCGRRVAGGGRRAAV

--------------------------------------------------------------
>2764_2764_13_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000373608_length(transcript)=1978nt_BP=211nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT
GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC
GGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGA
GCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAG
CCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCT
ACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCAGCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA
CCCACTCCCTCCTTCCCCAGTTGTTCCCTTCAGACTCAGGGGCTCCACCAATGCCATCCCAAAACAGGGTCAGACACTGCCCAGCTTCCC
TCCAGGAGGTTCTTGTCTCTGTGTAAGGGCTTGTCTCCCTCCCAGTTTTTCTTTTGCTCCACGTCATTTTGTCAGGCTGGTTATAAGCCG
GAGGCAGCTTTAACCAGCCCCCAGGGATGATTGTGAAGGAGGCCCCTCCCCTTGTGAGGAGGGGGCACTCCTCTCCAGCCCCTGGTACCA
CAGTCCTCACGATGGTGCAGTGATTTCTAGCCAGGCGTCAAGATGCGCTGCTTTCCCTCTCCTGCCTCATCCCTTGTTGGCAGCTCCAGT
TCAGGCCGTGGAGGGACGTGATGCTGGGCTGTGTTTACTAAACCCACGGGTTTTCAGCCTCTTAAGCCCAGCTCCGATCTCCAATTAGTT
GAGAGCGCTGGGTTGACTAACCTCTGGTATCTGAGCACAGACAGAGGGTGCTGTGGGTCTGCTGGGTGGCAGAAATGGTTCCTTCCGGCT
TGGCGTTCTCTCCTGGCCACTCTTCCTGCTGCCTCTGACTACTCAGCCTTGTTTTCGGTGTGTAGGCCCCAGCTGCCCACTGGAACTGCC
GGCTAATGCTTGCTCTCCCAAGATCTTTAACTCCTCCTGGCTGCACCTGGGTAGGGATGGTGGCATCGATGCCCCTCTGTCTGCTGAAGG
ACCTGTTGCTGCTTCTGTCTTTTCACCCCTCCTTGGCTGATGACCCAGAGCCCTCTGATGATGGCATTCTCCTGGCAAGAGAAAAAGACT
TAACTAGACTTCTGAACTTGAACAGTTTCAGGTTATATTTTAATTTTTTTTTTTTTGTACAGGTTCTGATTCTAATACATTTCAACATGC
TTTTGTCCCCCCTCGTGTCAATATTTGTTATAGACTAATCGCCGGGGATTTTTCACCTGGTTGGAGGGTGGGGGTGGGGTGGGGTGTGTG
TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTAGGTCCTGGACTGATTAAAGTTCATTGAGGAAAAAGCACATTTTACAAC
AAAAAAATAAAAGTGTAGATTTAATGTATGTGACTGGGGTTTGGGGTTGCATACCTGGTGGATCTTGAGGGGCTGGGATTAGGGTGGTTC
AGGAAAATGTGATGCTGTTTCCCCATGTTTAGCCATGGTCAAAAAATGGATTTCTCCTTTTTCTAAAATGTCCAGCAACTGCCTACTGTT
GATCAAATGTTGAAGTATTCTTGTTTCCCTTTTAAGCCAATCCATGTGCCCACATAACATTATGCCCAAGTGGAGAGTTCACTTTAATTT
CCAAAGTATGTTTCATGCAGCCCCCTGTCAGCTGCTCTGTGGAAAAGGGGTTCTGTTATGAAATAAATGTTGCACTCCCTGCATCCCA

>2764_2764_13_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000373608_length(amino acids)=131AA_BP=
MARNHCTIVRTVVPGAGEECPLLTRGGASFTIIPGGWLKLPPAYNQPDKMTWSKRKTGRETSPYTETRTSWREAGQCLTLFWDGIGGAPE
SEGNNWGRREWVRGSNSFSGTVPTGWGGAGEGTGRSGTHCR

--------------------------------------------------------------
>2764_2764_14_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000409091_length(transcript)=420nt_BP=211nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT
GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC
GGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGA
GCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAG
CCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGG

>2764_2764_14_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000409091_length(amino acids)=87AA_BP=63
MANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDGYQHQEDTQSHRILLGSGDGAAAG

--------------------------------------------------------------
>2764_2764_15_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000409295_length(transcript)=540nt_BP=211nt
GTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCT
GCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATAC
GGGCTGAATGTGGAGAGGGTCTTCCAGGACGGTTACCAACATCAAGAAGACACTCAAAGCCACCGCATCCTCCTCGGCTCAGGAGATGGA
GCAGCAGCTGGCTGAACGGGAGTGTCCCCCTCACGCTGAGCAGAGGCAGCCCACCAAGAAGATGTCCAAAGTGAAAGGTCTGGTCTCCAG
CCGCCACTAGGGCCGGCTGGGGCAGCTGGCACTCACCAGGCCTGGGTCAGGTGGGGAGGGGACACCAAGGGCCCATTTCCTCCCCTCTCT
ACCTGCAGTGAGTTCCAGACCTGCCCGTCCCCTCACCAGCGCCTCCCCACCCTGTTGGTACTGTTCCAGAAAAACTGTTACTCCCCCTCA


>2764_2764_15_AGAP1-COPS7B_AGAP1_chr2_236659132_ENST00000428334_COPS7B_chr2_232672196_ENST00000409295_length(amino acids)=87AA_BP=63
MANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDGYQHQEDTQSHRILLGSGDGAAAG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGAP1-COPS7B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP1-COPS7B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP1-COPS7B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGAP1C0004352Autistic Disorder1CTD_human