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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:AGAP1-SOX7 (FusionGDB2 ID:HG116987TG83595)

Fusion Gene Summary for AGAP1-SOX7

check button Fusion gene summary
Fusion gene informationFusion gene name: AGAP1-SOX7
Fusion gene ID: hg116987tg83595
HgeneTgene
Gene symbol

AGAP1

SOX7

Gene ID

116987

83595

Gene nameArfGAP with GTPase domain, ankyrin repeat and PH domain 1SRY-box transcription factor 7
SynonymsAGAP-1|CENTG2|GGAP1|cnt-g2-
Cytomap('AGAP1')('SOX7')

2q37.2

8p23.1

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2transcription factor SOX-7SRY (sex determining region Y)-box 7SRY-box 7
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000304032, ENST00000336665, 
ENST00000409457, ENST00000409538, 
ENST00000428334, 
Fusion gene scores* DoF score49 X 18 X 17=149945 X 5 X 3=75
# samples 485
** MAII scorelog2(48/14994*10)=-4.96520709119934
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AGAP1 [Title/Abstract] AND SOX7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAGAP1(236403493)-SOX7(10683754), # samples:2
Anticipated loss of major functional domain due to fusion event.AGAP1-SOX7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-SOX7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-SOX7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
AGAP1-SOX7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSOX7

GO:0001706

endoderm formation

18682240

TgeneSOX7

GO:0008285

negative regulation of cell proliferation

19108950

TgeneSOX7

GO:0043280

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

19108950

TgeneSOX7

GO:0045892

negative regulation of transcription, DNA-templated

19108950

TgeneSOX7

GO:0060828

regulation of canonical Wnt signaling pathway

19108950


check buttonFusion gene breakpoints across AGAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SOX7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1544-01AAGAP1chr2

236403493

+SOX7chr8

10683754

-


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Fusion Gene ORF analysis for AGAP1-SOX7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000304032ENST00000304501AGAP1chr2

236403493

+SOX7chr8

10683754

-
5CDS-intronENST00000336665ENST00000304501AGAP1chr2

236403493

+SOX7chr8

10683754

-
5CDS-intronENST00000409457ENST00000304501AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000304032ENST00000553390AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000304032ENST00000554914AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000336665ENST00000553390AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000336665ENST00000554914AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000409457ENST00000553390AGAP1chr2

236403493

+SOX7chr8

10683754

-
In-frameENST00000409457ENST00000554914AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-3CDSENST00000409538ENST00000553390AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-3CDSENST00000409538ENST00000554914AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-3CDSENST00000428334ENST00000553390AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-3CDSENST00000428334ENST00000554914AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-intronENST00000409538ENST00000304501AGAP1chr2

236403493

+SOX7chr8

10683754

-
intron-intronENST00000428334ENST00000304501AGAP1chr2

236403493

+SOX7chr8

10683754

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336665AGAP1chr2236403493+ENST00000554914SOX7chr810683754-21047434211764447
ENST00000336665AGAP1chr2236403493+ENST00000553390SOX7chr810683754-21047434211764447
ENST00000304032AGAP1chr2236403493+ENST00000554914SOX7chr810683754-21047434211764447
ENST00000304032AGAP1chr2236403493+ENST00000553390SOX7chr810683754-21047434211764447
ENST00000409457AGAP1chr2236403493+ENST00000554914SOX7chr810683754-21227614391782447
ENST00000409457AGAP1chr2236403493+ENST00000553390SOX7chr810683754-21227614391782447

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336665ENST00000554914AGAP1chr2236403493+SOX7chr810683754-0.0113297660.98867023
ENST00000336665ENST00000553390AGAP1chr2236403493+SOX7chr810683754-0.0113297660.98867023
ENST00000304032ENST00000554914AGAP1chr2236403493+SOX7chr810683754-0.0113297660.98867023
ENST00000304032ENST00000553390AGAP1chr2236403493+SOX7chr810683754-0.0113297660.98867023
ENST00000409457ENST00000554914AGAP1chr2236403493+SOX7chr810683754-0.0117545670.9882455
ENST00000409457ENST00000553390AGAP1chr2236403493+SOX7chr810683754-0.0117545670.9882455

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Fusion Genomic Features for AGAP1-SOX7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for AGAP1-SOX7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:236403493/chr8:10683754)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSOX7chr2:236403493chr8:10683754ENST000003045010245_1130389.0DNA bindingHMG box
TgeneSOX7chr2:236403493chr8:10683754ENST0000030450102268_3880389.0DomainSox C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118346_58854858.0DomainPH
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118609_72954858.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117346_58854805.0DomainPH
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117609_72954805.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110346_58854406.0DomainPH
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110609_72954406.0DomainArf-GAP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118122_12654858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118178_18154858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+11878_8554858.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117122_12654805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117178_18154805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+11778_8554805.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110122_12654406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110178_18154406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+11078_8554406.0Nucleotide bindingGTP
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+11866_27654858.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+11766_27654805.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+11066_27654406.0RegionNote=Small GTPase-like
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118768_79754858.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118801_83054858.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117768_79754805.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117801_83054805.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110768_79754406.0RepeatNote=ANK 1
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110801_83054406.0RepeatNote=ANK 2
HgeneAGAP1chr2:236403493chr8:10683754ENST00000304032+118624_64754858.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr8:10683754ENST00000336665+117624_64754805.0Zinc fingerC4-type
HgeneAGAP1chr2:236403493chr8:10683754ENST00000409457+110624_64754406.0Zinc fingerC4-type


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Fusion Gene Sequence for AGAP1-SOX7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2784_2784_1_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000304032_SOX7_chr8_10683754_ENST00000553390_length(transcript)=2104nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCG
TGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCT
GCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCC
GGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGA
CAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCC
GAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTC
CTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCT
CCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCC
TGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGG
CTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCA
CCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCAT
CTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCC
CTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGG
CCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTT
TAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCC

>2784_2784_1_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000304032_SOX7_chr8_10683754_ENST00000553390_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------
>2784_2784_2_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000304032_SOX7_chr8_10683754_ENST00000554914_length(transcript)=2104nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCG
TGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCT
GCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCC
GGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGA
CAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCC
GAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTC
CTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCT
CCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCC
TGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGG
CTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCA
CCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCAT
CTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCC
CTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGG
CCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTT
TAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCC

>2784_2784_2_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000304032_SOX7_chr8_10683754_ENST00000554914_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------
>2784_2784_3_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000336665_SOX7_chr8_10683754_ENST00000553390_length(transcript)=2104nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCG
TGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCT
GCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCC
GGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGA
CAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCC
GAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTC
CTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCT
CCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCC
TGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGG
CTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCA
CCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCAT
CTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCC
CTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGG
CCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTT
TAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCC

>2784_2784_3_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000336665_SOX7_chr8_10683754_ENST00000553390_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------
>2784_2784_4_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000336665_SOX7_chr8_10683754_ENST00000554914_length(transcript)=2104nt_BP=743nt
CGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCCCGGCGCGCCGGGCGGCGC
AGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGCCCTCGGCCCCGGCGCTCG
GAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGCTCAGGAAGTCACCCGAGC
AAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGCTGACCCGGGACGCCGGGG
CCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCCGCGCCTTTCTTCTCGCGC
CTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCCCCGGGGCGCGGGGCGGCG
GCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGCTGCCATCCGGGCCGAGAT
CCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGTGCTGCAGAACCAGATCCG
GGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCG
TGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCT
GCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCC
GGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGA
CAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCC
GAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTC
CTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCT
CCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCC
TGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGG
CTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCA
CCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCAT
CTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCC
CTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGG
CCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTT
TAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCC

>2784_2784_4_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000336665_SOX7_chr8_10683754_ENST00000554914_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------
>2784_2784_5_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000409457_SOX7_chr8_10683754_ENST00000553390_length(transcript)=2122nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTC
CAAAATCTCCAAAAACCGTGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGT
GGACGAGGCGGAGCGGCTGCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCT
GTGCAAGCGCGTGGACCCGGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGC
GCTGGGGGAGAAGGAGGACAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGG
TGGCGGCGGCGGCACCCCGAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCC
GGAGCAGACCTTCTTCTCCTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGA
GTACGCCCCAAGCCCTCTCCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACC
CGGCTGTCCCCCATCTCCTGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCC
GCCTCCTGAGCACCCTGGCTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTA
TTTGAACACTCCTGGCCACCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCC
CACAGAGACCAGCCTCATCTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGT
CCGGTCAGCCCTCGCGCCCTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCA
GGGAGGTCTGAACTGCGGCCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAG
CCCCTGCAGCCCACATTTTAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGA

>2784_2784_5_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000409457_SOX7_chr8_10683754_ENST00000553390_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------
>2784_2784_6_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000409457_SOX7_chr8_10683754_ENST00000554914_length(transcript)=2122nt_BP=761nt
GGCGCTCGGAGCGGGCTCCGCGGCTTGCAAGGCGCCTGCGACTCGGTCCCAGGTCGGCGGGCGGCGCACGGCGGGCTCGCGCGGGGGCCC
CGGCGCGCCGGGCGGCGCAGTACGCAGCGCGCGGACCCACGCCACGGCCAGGAGCCCAGAGCAGCGCGGCCACACTGCCCAGGGGTCGGC
CCTCGGCCCCGGCGCTCGGAGCGCGGCGGCTGCCTGGGCTTTAATGGCTGCTCCGCGGAGCAGCGCCTAGGGCTGGAAGGCGGCTGCGGC
TCAGGAAGTCACCCGAGCAAGCCTCCTTCGGGGCCGGCCGCACCCGCCGCGGCGCGCTCCATGGGGGCGCGCTCCCCCCGGGCGGCCCGC
TGACCCGGGACGCCGGGGCCCGCTCGCTCGCCGGCCGCGCGTCCCGGCCATGAACTGAGCCCGCGGGCCAGCCCCGCGCCTGCTCCGCCC
GCGCCTTTCTTCTCGCGCCTCCTCCGCCCGCCGCCGGCGGGCCCGGCTCCCCGGGGGCTGCGGCGCCCCGGGCTCGGCGGCCCGCGGGCC
CCGGGGCGCGGGGCGGCGGCGGCGGGGGGCGCGCGGCTCCGGGCGCGGCGCCTGCACCATGAACTACCAGCAGCAGCTGGCCAACTCGGC
TGCCATCCGGGCCGAGATCCAGCGCTTCGAGTCGGTCCACCCCAACATCTACTCCATCTACGAGCTGCTGGAGCGCGTGGAGGAGCCGGT
GCTGCAGAACCAGATCCGGGAGCACGTCATCGCCATCGAAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTC
CAAAATCTCCAAAAACCGTGTTCACTATATGAAATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGT
GGACGAGGCGGAGCGGCTGCGCCTGCAGCACATGCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCT
GTGCAAGCGCGTGGACCCGGGCTTCCTTCTGAGCTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGC
GCTGGGGGAGAAGGAGGACAGGGGTGAGTACTCCCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGG
TGGCGGCGGCGGCACCCCGAGCAGTGTGGACACGTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCC
GGAGCAGACCTTCTTCTCCTCCCCCTGCCAGGAGGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGA
GTACGCCCCAAGCCCTCTCCACTGTAGCCACCCCCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACC
CGGCTGTCCCCCATCTCCTGCCTATTACTCCCCGGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCC
GCCTCCTGAGCACCCTGGCTTCGACGCCCTGGATCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTA
TTTGAACACTCCTGGCCACCCAGACTCCGCCACAGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCC
CACAGAGACCAGCCTCATCTCCGTCCTGGCTGATGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGT
CCGGTCAGCCCTCGCGCCCTCTCCTTCTTGTGCCTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCA
GGGAGGTCTGAACTGCGGCCCCAGAGCCTTTGGCCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAG
CCCCTGCAGCCCACATTTTAAGTATATTCCTTCAAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGA

>2784_2784_6_AGAP1-SOX7_AGAP1_chr2_236403493_ENST00000409457_SOX7_chr8_10683754_ENST00000554914_length(amino acids)=447AA_BP=107
MLRPRLSSRASSARRRRARLPGGCGAPGSAARGPRGAGRRRRGARGSGRGACTMNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERV
EEPVLQNQIREHVIAIEDSSDKKEKKSFSLEEKSKISKNRVHYMKFTKGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKKQ
AKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTPPEMSPLD
VLEPEQTFFSSPCQEEHGHPRRIPHLPGHPYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHLG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for AGAP1-SOX7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for AGAP1-SOX7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AGAP1-SOX7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAGAP1C0004352Autistic Disorder1CTD_human